CN101954024A - Traditional Chinese medicament for treating diabetic foot - Google Patents

Traditional Chinese medicament for treating diabetic foot Download PDF

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CN101954024A
CN101954024A CN2010102981988A CN201010298198A CN101954024A CN 101954024 A CN101954024 A CN 101954024A CN 2010102981988 A CN2010102981988 A CN 2010102981988A CN 201010298198 A CN201010298198 A CN 201010298198A CN 101954024 A CN101954024 A CN 101954024A
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traditional chinese
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diabetic foot
chinese medicine
medicament
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刘新壮
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Lvyuan Qiuzheng Technology Development Co Ltd
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Lvyuan Qiuzheng Technology Development Co Ltd
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Abstract

The invention discloses a traditional Chinese medicament for treating diabetic foot, which belongs to the field of traditional Chinese medicaments for treating diabetes. The invention aims to traditional Chinese medicament for treating diabetic foot with good effect and quick response. The traditional Chinese medicament is prepared from the raw materials including ash bark, Chinese angelica, salvia miltiorrhiza bunge, lucid ganoderma, pseudo-ginseng root, chinaroot greenbrier and the like. The traditional Chinese medicament has the effects of strengthening the body resistance and archaeus, tonifying qi, nourishing blood, activating blood, eliminating stasis and clearing dampness and heat, and has the advantages of obvious effect, accurate medicament efficacy and quick response.

Description

一种治疗糖尿病足的中药 A kind of traditional Chinese medicine for treating diabetic foot

技术领域technical field

本发明属于治疗糖尿病的中药领域。The invention belongs to the field of traditional Chinese medicine for treating diabetes.

背景技术Background technique

糖尿病足是糖尿病常见的多发的并发症,系糖尿病大血管病变和神经病变所致。治疗难度很大,是目前国内尚未攻克的一个治疗“难题”。目前用于治疗糖尿病足的西药和中药,存在一些明显的不足:一是效果不够明显,二是见效比较迟缓,大量患者面对糖尿病足束手无策,患肢久治不愈,不断恶化,最后不得不做“截肢”手术,导致残废。患者花自己的钱,锯自己的腿,痛苦而又无奈!Diabetic foot is a common and multiple complication of diabetes, which is caused by diabetic macroangiopathy and neuropathy. Treatment is very difficult, and it is a treatment "difficulty" that has not yet been overcome in China. There are some obvious deficiencies in the western medicine and traditional Chinese medicine currently used to treat diabetic foot: one is that the effect is not obvious enough, and the other is that the effect is relatively slow. "Surgery, resulting in disability. The patient spends his own money and saws his own leg, which is painful and helpless!

针对以上提出的问题,本发明提供一种治疗糖尿病足的中药,它能解决以往此类中药治疗中效果不够明显,见效比较迟缓的问题,效果好、见效快,具有效果显著,药效确切,见效较快的优点。In view of the problems raised above, the present invention provides a Chinese medicine for treating diabetic foot, which can solve the problem that the effect of this kind of Chinese medicine in the past is not obvious enough, and the effect is relatively slow. It has good effect, quick effect, remarkable effect and exact drug effect. The advantage of quicker results.

发明内容Contents of the invention

本发明是通过以下技术方案来实现的:The present invention is achieved through the following technical solutions:

1、一种治疗糖尿病足的中药,采用中药原料制备,配方为(按重量比):1, a kind of Chinese medicine for the treatment of diabetic foot, adopts Chinese medicine raw material to prepare, and formula is (by weight):

秦皮5——15份  当归6——18份  丹参6——18份Qinpi 5—15 parts Angelica 6—18 parts Salvia 6—18 parts

灵芝6——18份  三七3——9份   菝葜6——18份Ganoderma lucidum 6—18 parts Panax notoginseng 3—9 parts Smilax 6—18 parts

这种治疗糖尿病足的中药是由下列方法制成的:This traditional Chinese medicine for treating diabetic foot is made by the following method:

(1)按上述重量比,将灵芝用水提醇沉法提取灵芝多糖,工艺流程如下:将灵芝破碎成颗粒状,过40目筛→用1∶20的热水(95℃)浸提→浸提液减压、浓缩→用3倍体积的95%乙醇混合、静置10-12小时、离心→加75%的乙醇,沉淀多糖→烘干得灵芝多糖提取物细粉;(1) According to the above weight ratio, extract Ganoderma lucidum polysaccharides from Ganoderma lucidum with water extraction and alcohol precipitation method, the process is as follows: crush Ganoderma lucidum into granules, pass through a 40-mesh sieve → leaching with 1:20 hot water (95°C) → leaching Extract the liquid under reduced pressure, concentrate → mix with 3 times the volume of 95% ethanol, let stand for 10-12 hours, centrifuge → add 75% ethanol, precipitate polysaccharide → dry to obtain fine powder of Ganoderma lucidum polysaccharide extract;

(2)按上述重量比,将秦皮、当归、丹参、菝葜常规水提取工艺提取,制成提取物浸膏细粉;(2) According to the above weight ratio, the conventional water extraction process of Qinpi, Angelica, Salvia Miltiorrhiza, and Sarsaparilla is extracted to make extract extract fine powder;

(3)按上述重量比,将三七研成细粉,与上述(1)、(2)两种提取物细粉混合,搅拌均匀,制成中药颗粒剂、胶囊剂、片剂。(3) According to the above weight ratio, grind Radix Notoginseng into a fine powder, mix with the fine powder of the above two kinds of extracts (1) and (2), stir evenly, and make traditional Chinese medicine granules, capsules, and tablets.

本发明根据民间传统配方,根据中医扶正培本、活血化瘀的理论,精心研制而成。我们研究认为,糖尿病足的病机,主要归于“热”和“瘀”。糖尿病患者大多数免疫力低下,阴液亏虚,虚热内生,耗灼津液,造成血液粘稠,血管瘀阻,血液流动缓慢,患肢供血不足。这是患肢发生大血管病变和神经病变的主要原因。据此,本发明以扶正为重点,清热利湿解毒,行气活血化瘀,在治疗效果上,取得了突破——在西医西药只能“截肢”的糖尿病足,使用本发明可不必“截肢”,使患肢得以康复。可以说,这是个较为重大的发明。本方之中灵芝、当归扶正培本,益气养血,补益五脏,增强机体免疫力,这是修复血管病变、神经病变的重要前提;丹参、三七补血养血,活血化瘀,灵芝、当归与丹参、三七为伍,气旺血足,促进血液清洁,流动加快,去瘀血腐肉而生新肌;伍以秦皮清热燥湿,收敛,明目;菝葜祛风利湿,解毒散瘀,善治反复发作的慢性肢体溃疡。诸药配伍,相得益彰,共奏扶正培本,益气养血,活血化瘀,清热利湿之功,效果好,见效快,具有效果显著,药效确切,见效较快的优点。The present invention is elaborately developed according to the folk traditional formula and the theory of traditional Chinese medicine of strengthening the body and strengthening the body, promoting blood circulation and removing blood stasis. Our research believes that the pathogenesis of diabetic foot is mainly attributed to "heat" and "stasis". Most diabetic patients have low immunity, deficiency of yin fluid, endogenous deficiency heat, consumption of body fluid, resulting in thick blood, stasis of blood vessels, slow blood flow, and insufficient blood supply to affected limbs. This is the main cause of macrovascular disease and neuropathy in the affected limb. Accordingly, the present invention focuses on strengthening the body, clearing away heat and dampness, detoxifying, promoting qi, promoting blood circulation and removing blood stasis, and has made a breakthrough in the therapeutic effect-diabetic feet that can only be "amputated" by Western medicine and western medicine, using the present invention does not need to "amputate" ", so that the limb can be recovered. It can be said that this is a relatively important invention. In this prescription, Ganoderma lucidum and Angelica Fuzheng Peiben can nourish qi and blood, nourish the five internal organs, and enhance the body's immunity. This is an important prerequisite for repairing vascular disease and neuropathy; Angelica, together with Danshen and Panax notoginseng, promotes qi and blood, promotes blood cleansing, speeds up blood flow, removes blood stasis and carrion and generates new muscle; Wu Yiqin skin clears away heat and dampness, astringes, improves eyesight; Blood stasis, good at treating recurrent chronic limb ulcers. All the medicines are compatible and complement each other, and they play the functions of strengthening the body, nourishing qi and nourishing blood, promoting blood circulation and removing blood stasis, clearing away heat and dampness, and have good effect and quick effect.

具体实施方式Detailed ways

通过以下实施方式对本发明做具体说明:The present invention is specifically described by the following embodiments:

1、取以下配方(重量按克为单位):1. Take the following formula (weight is in grams):

秦皮50克  当归60克  丹参60克Qinpi 50g Angelica 60g Salvia 60g

灵芝60克  三七30克  菝葜60克Ganoderma lucidum 60g Sanqi 30g Smilax 60g

按规定重量,用水提醇沉法将灵芝进行提取;用常规水提取工艺将秦皮、当归、丹参、菝葜提取,共制成提取物细粉58克,将三七研成细粉,与上述提取物细粉混合,搅拌均匀,制成细小颗粒,装入0号胶囊,制成中药胶囊314粒,每粒胶囊内含中药细粉及提取物0.28克。Extract Ganoderma lucidum by water extraction and alcohol precipitation method according to the specified weight; extract Qinpi, Angelica, Salvia miltiorrhiza, and Smilax chinensis with conventional water extraction process, and make a total of 58 grams of extract fine powder, grind Sanqi into fine powder, and mix with the above The fine powder of the extract is mixed, stirred evenly, made into fine particles, packed into No. 0 capsules, and made into 314 Chinese medicine capsules, each capsule containing 0.28 grams of the fine powder of Chinese medicine and the extract.

2、取以下配方(重量按克为单位):2. Take the following formula (weight is in grams):

秦皮100克  当归120克  丹参120克Qinpi 100g Angelica 120g Salvia 120g

灵芝120克  三七60克   菝葜120克Ganoderma lucidum 120g Panax notoginseng 60g Smilax 120g

按上述同样的方法,制成中药胶囊628粒,每粒胶囊内含中药细粉及提取物0.28克。By the same method as above, 628 Chinese medicine capsules were made, each capsule containing 0.28 grams of Chinese medicine fine powder and extract.

3、取以下配方(重量按克为单位):3. Take the following formula (the weight is in grams):

秦皮150克  当归180克  丹参180克Qinpi 150g Angelica 180g Salvia 180g

灵芝180克  三七90克   菝葜180克Ganoderma lucidum 180g Sanqi 90g Smilax 180g

按上述同样的方法,制成中药胶囊942粒,每粒胶囊内含中药细粉及提取物0.28克。By above-mentioned same method, make 942 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.

4、取以下配方(按重量比):4. Take the following formula (by weight):

秦皮7份  当归9份  丹参9份Qinpi 7 parts Angelica 9 parts Salvia 9 parts

灵芝9份  三七4份  菝葜9份Ganoderma lucidum 9 parts Panax notoginseng 4 parts Smilax 9 parts

按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.

5、取以下配方(按重量比):5. Take the following formula (by weight):

秦皮13份  当归17份  丹参17份Qinpi 13 parts Angelica 17 parts Salvia 17 parts

灵芝17份  三七8份   菝葜17份Ganoderma lucidum 17 parts Panax notoginseng 8 parts Smilax 17 parts

按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.

临床资料:clinical information:

本发明以中医糖尿病足为例,经6例临床观察。选择中医诊断糖尿病足为标准:糖尿病患者形体消瘦,肢软乏力;患肢发凉,血液循环不畅;肌肉萎缩;下肢脉搏微弱,间歇性跛行;患肢皮肤发黑、发紫,组织坏死;肢体麻木,肢端疼痛;患肢肢端溃疡、溃烂,流血流脓,久不愈合。如上症状,即可确诊。在确诊观察的对象中,男性4例,女性2例,无其它严重疾病,年龄为49岁-78岁,平均年龄65.3岁。The present invention takes TCM diabetic foot as an example, through 6 clinical observations. Diagnosis of diabetic foot by traditional Chinese medicine is selected as the standard: diabetic patients are emaciated, limbs are weak and weak; affected limbs are cold, blood circulation is not smooth; muscle atrophy; lower limb pulse is weak, intermittent claudication; Limb numbness, extremity pain; affected extremity ulcer, ulceration, bleeding and pus, long-term non-healing. The above symptoms can be diagnosed. Among the confirmed observation objects, there were 4 males and 2 females, without other serious diseases, aged from 49 to 78 years old, with an average age of 65.3 years.

疗效判定:Judgment of curative effect:

1、显效:体质增强,身上有劲;肢体温暖,发凉消失;皮肤颜色由黑紫逐步变白(正常皮肤颜色),血液循环明显改善;患肢麻木、肢端疼痛明显减轻;肢端溃烂缓解、愈合。1. Significant effect: Physical fitness is enhanced, body is strong; limbs are warm, and coldness disappears; skin color gradually turns from black to white (normal skin color), blood circulation is significantly improved; numbness of affected limbs, pain in extremities are significantly relieved; extremity ulceration is relieved ,heal.

2、有效:体质增强,身上有劲,肢体温暖,血液循环改善;肢体麻木、疼痛有所缓解。2. Effective: Physical fitness is enhanced, body is strong, limbs are warm, blood circulation is improved; limb numbness and pain are relieved.

3、无效:病症无变化。3. Ineffective: no change in symptoms.

临床实验时,除降糖药物以外,停服其它药物和保健营养品。服用本发明中药胶囊,观察6个月,为一个疗程。服用方法:每日2次,每次4粒胶囊,每粒胶囊内含中药细粉及提取物0.28克,饭后温开水送服,1个月后症状即有缓解,服用6个月后,症状明显改善。临床实验的6人中,显效2人,有效3人,无效1人,总有效率83.3%。During clinical trials, except for hypoglycemic drugs, stop taking other drugs and health nutrition products. Take Chinese medicine capsule of the present invention, observe 6 months, be a course of treatment. Dosing method: 2 times a day, 4 capsules each time, each capsule contains 0.28 grams of fine powder and extract of traditional Chinese medicine, take it with warm water after meals, the symptoms will be relieved after 1 month, and after 6 months of taking, Symptoms improved significantly. Among the 6 people in the clinical trial, 2 were markedly effective, 3 were effective, and 1 was ineffective, with a total effective rate of 83.3%.

Claims (1)

1. Chinese medicine for the treatment of diabetic foot, it is characterized in that: it is to make with the component of following weight ratio: Cortex Fraxini 5---15 parts, Radix Angelicae Sinensis 5---18 parts, Radix Salviae Miltiorrhizae 5---18 parts, Ganoderma 5---18 parts, Radix Notoginseng 3---9 parts, Rhizoma Smilacis Chinensis 5---18 parts.
CN2010102981988A 2010-09-29 2010-09-29 Traditional Chinese medicament for treating diabetic foot Pending CN101954024A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102380063A (en) * 2011-07-23 2012-03-21 北京绿源求证科技发展有限责任公司 Chinese medicament for treating diabetic foot
CN102716435A (en) * 2012-05-05 2012-10-10 周士菊 Traditional Chinese medicine feet-soaking preparation for treating diabetic foot
CN103735839A (en) * 2014-01-09 2014-04-23 肖玉良 Traditional Chinese medicine external application agent for treating diabetic foot

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102380063A (en) * 2011-07-23 2012-03-21 北京绿源求证科技发展有限责任公司 Chinese medicament for treating diabetic foot
CN102716435A (en) * 2012-05-05 2012-10-10 周士菊 Traditional Chinese medicine feet-soaking preparation for treating diabetic foot
CN103735839A (en) * 2014-01-09 2014-04-23 肖玉良 Traditional Chinese medicine external application agent for treating diabetic foot
CN103735839B (en) * 2014-01-09 2016-04-06 肖玉良 A kind of external traditional Chinese medicinal application for the treatment of diabetic foot

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Application publication date: 20110126