CN102389547A - Traditional Chinese medicine for treating diabetic foot - Google Patents
Traditional Chinese medicine for treating diabetic foot Download PDFInfo
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- CN102389547A CN102389547A CN2011102977493A CN201110297749A CN102389547A CN 102389547 A CN102389547 A CN 102389547A CN 2011102977493 A CN2011102977493 A CN 2011102977493A CN 201110297749 A CN201110297749 A CN 201110297749A CN 102389547 A CN102389547 A CN 102389547A
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Abstract
一种治疗糖尿病足的中药,属治疗糖尿病的中药领域;其目的是效果好、见效快;本发明采用沙参、当归、地黄、灵芝、三七、菝葜等原料制成;它具有扶正培本,益气养血,活血化瘀,清热利湿的作用,具有效果显著,药效确切,见效较快的优点。This invention relates to a traditional Chinese medicine for treating diabetic foot, belonging to the field of traditional Chinese medicine for treating diabetes. Its purpose is to achieve good and rapid effects. The invention is made from raw materials such as Adenophora stricta, Angelica sinensis, Rehmannia glutinosa, Ganoderma lucidum, Panax notoginseng, and Smilax china. It has the effects of strengthening the body's resistance, nourishing qi and blood, promoting blood circulation and removing blood stasis, and clearing heat and dampness. It has the advantages of significant effects, definite efficacy, and rapid effect.
Description
技术领域 technical field
本发明属于治疗糖尿病的中药领域。 The invention belongs to the field of traditional Chinese medicine for treating diabetes.
背景技术 Background technique
糖尿病足是糖尿病常见的多发的并发症,系糖尿病大血管病变和神经病变所致。由于抗生素对此无效,治疗难度很大,是目前国内外尚未攻克的一个治疗“难题”。目前用于治疗糖尿病足的西药和中药,存在一些明显的不足:一是效果不够明显,二是见效比较迟缓,大量患者面对糖尿病足束手无策,患肢久治不愈,不断恶化,最后不得不做“截肢”手术,导致残废。患者花自己的钱,锯自己的腿,痛苦而又无奈! Diabetic foot is a common and multiple complication of diabetes, which is caused by diabetic macroangiopathy and neuropathy. Because antibiotics are ineffective for this, the treatment is very difficult, and it is a treatment "difficulty" that has not yet been overcome at home and abroad. There are some obvious deficiencies in the western medicine and traditional Chinese medicine currently used to treat diabetic foot: one is that the effect is not obvious enough, and the other is that the effect is relatively slow. "Surgery, resulting in disability. The patient spends his own money and saws his own leg, which is painful and helpless!
针对以上提出的问题,本发明提供一种治疗糖尿病足的中药,它能解决以往此类中药治疗中效果不够明显,见效比较迟缓的问题,效果好、见效快,具有效果显著,药效确切,见效较快的优点。 In view of the problems raised above, the present invention provides a Chinese medicine for treating diabetic foot, which can solve the problem that the effect of this kind of Chinese medicine in the past is not obvious enough, and the effect is relatively slow. It has good effect, quick effect, remarkable effect and exact drug effect. The advantage of quicker results.
发明内容 Contents of the invention
本发明是通过以下技术方案来实现的: The present invention is achieved through the following technical solutions:
1、一种治疗糖尿病足的中药,采用中药原料制备,配方按重量配比为: 1, a kind of Chinese medicine for the treatment of diabetic foot, adopts Chinese medicine raw material to prepare, and formula is by weight ratio:
沙参4——12份 当归6——18份 地黄6——18份 Ginseng 4——12 parts Angelica 6——18 parts Rehmannia 6——18 parts
灵芝6——18份 三七1——3份 菝葜4——12份 Ganoderma lucidum 6——18 servings Sanqi 1——3 servings Smilax 4——12 servings
这种治疗糖尿病足的中药是由下列方法制成的: This traditional Chinese medicine for treating diabetic foot is made by the following method:
(1)按上述重量比,将沙参、当归、地黄、灵芝、菝葜常规水提取工艺提取,制成浸膏,烘干粉碎,得提取物细粉; (1) According to the above weight ratio, extract Adenophora, Angelica, Rehmannia glutinosa, Ganoderma lucidum, and Smilax with conventional water extraction process to make extract, dry and pulverize to obtain extract fine powder;
(2)按上述重量比,将三七研成细粉,与上述(1)提取物细粉混合,搅拌均匀,制成中药颗粒剂、胶囊剂、片剂。 (2) Grind notoginseng into fine powder according to the above weight ratio, mix with the fine powder of the extract from (1) above, and stir evenly to make traditional Chinese medicine granules, capsules, and tablets.
本发明根据民间传统配方,根据中医扶正培本、活血化瘀的理论,精心研制而成。我们研究认为,糖尿病足的病机,主要归于“热”和“瘀”。糖尿病患者大多数免疫力低下,阴液亏虚,虚热内生,耗灼津液,造成血液粘稠,血管瘀阻,血液流动缓慢,患肢供血不足。这是患肢发生大血管病变和神经病变的主要原因。据此,本发明以扶正为重点,清热利湿解毒,行气活血化瘀,在治疗效果上,取得了突破——在西医西药只能“截肢”的糖尿病足,使用本发明可不必“截肢”,使患肢得以康复。可以说,这是个较为重大的发明。本方之中灵芝、当归扶正培本,益气养血,补益五脏,增强机体免疫力,这是修复患肢血管病变、神经病变的重要前提;地黄、三七补血养血,活血化瘀,灵芝、当归与地黄、三七为伍,气旺血足,促进血液清洁,流动加快,去瘀血腐肉而生新肌;生地黄性甘寒苦,用以清热滋阴,生津止渴;辅以沙参养阴清热,益肺生津;菝葜祛风利湿,解毒散瘀,善治反复发作的慢性肢体溃疡。诸药配伍,相得益彰,共奏扶正培本,益气养血,活血化瘀,清热利湿之功,效果好,见效快,具有效果显著,药效确切,见效较快的优点。 The present invention is elaborately developed according to the folk traditional formula and the theory of traditional Chinese medicine of strengthening the body and strengthening the body, promoting blood circulation and removing blood stasis. Our research believes that the pathogenesis of diabetic foot is mainly attributed to "heat" and "stasis". Most diabetic patients have low immunity, deficiency of yin fluid, endogenous deficiency heat, consumption of body fluid, resulting in thick blood, stasis of blood vessels, slow blood flow, and insufficient blood supply to affected limbs. This is the main cause of macrovascular disease and neuropathy in the affected limb. Accordingly, the present invention focuses on strengthening the body, clearing away heat and dampness, detoxifying, promoting qi, promoting blood circulation and removing blood stasis, and has made a breakthrough in the therapeutic effect-diabetic feet that can only be "amputated" by Western medicine and western medicine, using the present invention does not need to "amputate" ", so that the limb can be recovered. It can be said that this is a relatively important invention. In this prescription, Ganoderma lucidum and Angelica Fuzheng Peiben can nourish qi and blood, nourish the five internal organs, and enhance the body's immunity. This is an important prerequisite for repairing vascular disease and neuropathy in the affected limbs; Ganoderma lucidum, angelica, together with rehmannia glutinosa and notoginseng, promote blood circulation, promote blood cleansing, accelerate blood flow, remove blood stasis and carrion and generate new muscle; raw rehmannia glutinosa is sweet and cold, used for clearing heat and nourishing yin, promoting body fluid and quenching thirst; supplemented with sand ginseng for nourishing Yin clears heat, nourishes the lungs and promotes body fluid; Smilax sarsaparilla dispels wind and dampness, detoxifies and dissipates blood stasis, and is good at treating recurrent chronic limb ulcers. All the medicines are compatible and complement each other, and they play the functions of strengthening the body, nourishing qi and nourishing blood, promoting blood circulation and removing blood stasis, clearing away heat and dampness, and have good effect and quick effect.
具体实施方式 Detailed ways
通过以下实施方式对本发明做具体说明: The present invention is specifically described by the following embodiments:
1、取以下配方(重量按克为单位): 1. Take the following formula (weight in grams):
沙参400克 当归600克 地黄600克 400 grams of ginseng 600 grams of angelica 600 grams of rehmannia
灵芝600克 三七100克 菝葜400克 Ganoderma lucidum 600g 37 100g Smilax 400g
按规定重量,用常规水提取工艺将沙参、当归、地黄、灵芝、菝葜提取,制成提取物细粉260克,将三七研成细粉,与上述提取物细粉混合,搅拌均匀,制成细小颗粒,装入0号胶囊,制成中药胶囊1200粒,每粒胶囊内含中药细粉及提取物0.3克。 According to the specified weight, use the conventional water extraction process to extract the sand ginseng, angelica, rehmannia glutinosa, ganoderma lucidum, and sarsaparilla to make 260 grams of fine powder of the extract. Grind Sanqi into a fine powder, mix it with the fine powder of the above extract, and stir evenly , made into fine particles, packed into No. 0 capsules, and made into 1200 Chinese medicine capsules, each capsule containing 0.3 grams of Chinese medicine fine powder and extract.
2、取以下配方(重量按克为单位): 2. Take the following formula (the weight is in grams):
沙参800克 当归1200克 地黄1200克 Radix Ginseng 800 grams Angelica 1200 grams Rehmannia glutinosa 1200 grams
灵芝1200克 三七200克 菝葜800克 Ganoderma lucidum 1200g
按上述同样的方法,制成中药胶囊2400粒,每粒胶囊内含中药细粉及提取物0.3克。 By the above-mentioned same method, make 2400 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.3 gram.
3、取以下配方(重量按克为单位): 3. Take the following formula (the weight is in grams):
沙参1200克 当归1700克 地黄1700克 Radix Ginseng 1200g Angelica 1700g Rehmannia glutinosa 1700g
灵芝1700克 三七260克 菝葜1200克 Ganoderma lucidum 1700g
按上述同样的方法,制成中药胶囊3366粒,每粒胶囊内含中药细粉及提取物0.3克。 By the above-mentioned same method, 3366 Chinese medicine capsules were made, and each capsule contained Chinese medicine fine powder and 0.3 gram of extract.
4、取以下配方(按重量比): 4. Take the following formula (by weight ratio):
沙参5份 当归9份 地黄9份 5 parts of sand ginseng 9 parts of angelica 9 parts of rehmannia
灵芝9份 三七1份 菝葜6份 9 parts of Ganoderma lucidum 1 part of Panax notoginseng 6 parts of Smilax
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.3克。 By the above-mentioned same method, make Chinese medicine capsule, every capsule contains Chinese medicine fine powder and extract 0.3 gram.
5、取以下配方(按重量比): 5. Take the following formula (by weight ratio):
沙参7份 当归13份 地黄13份 7 parts of sand ginseng 13 parts of angelica 13 parts of rehmannia
灵芝13份 三七3份 菝葜7份 13 servings of Ganoderma lucidum 3 servings of Panax notoginseng 7 servings of Sarsaparilla
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.3克。 By the above-mentioned same method, make Chinese medicine capsule, every capsule contains Chinese medicine fine powder and extract 0.3 gram.
the
临床资料:clinical information:
本发明以中医糖尿病足为例,经26例临床观察。选择中医诊断糖尿病足为标准:糖尿病患者体质虚弱,肢软乏力;患肢发凉,血液循环不畅,脚背动脉搏动微弱或基本消失;患肢皮肤发黑、发紫,组织坏死;肢体麻木,肢端疼痛;患肢肢端溃疡、溃烂,流血流脓,久不愈合。如上症状,即可确诊。在确诊观察的对象中,男性16例,女性10例,无其它严重疾病,年龄为47岁—76岁,平均年龄59.6岁。 The present invention takes TCM diabetic foot as an example, through clinical observation of 26 cases. TCM diagnosis of diabetic foot is selected as the standard: diabetic patients have weak constitution and weak limbs; the affected limbs are cold, the blood circulation is not smooth, and the dorsal artery pulse is weak or basically disappears; the skin of the affected limbs is black, purple, tissue necrosis; limbs are numb, Pain in the extremities; ulcers and ulcers in the extremities of the affected extremities, bleeding and pus, which will not heal for a long time. The above symptoms can be diagnosed. Among the confirmed observation objects, there were 16 males and 10 females, without other serious diseases, ranging in age from 47 to 76 years old, with an average age of 59.6 years.
疗效判定: Judgment of curative effect:
1、显效:体质增强,身上有劲;患肢温暖,发凉消失,脚背动脉博动较前有力;皮肤颜色由黑紫逐步变白(正常皮肤颜色),血液循环明显改善;患肢麻木、疼痛等神经病变症状基本消失;患肢感染控制,完全愈合。 1. Significant effect: Physical fitness is enhanced, body is strong; affected limb is warm, coldness disappears, instep arterial pulse is stronger than before; skin color gradually turns from black to white (normal skin color), blood circulation is significantly improved; affected limb is numb and painful The symptoms of neuropathy basically disappeared; the infection of the affected limb was controlled and healed completely.
2、有效:体质增强,身上有劲,患肢温暖,血液循环改善;肢体麻木、疼痛有所缓解。 2. Effective: physical fitness is enhanced, the body is strong, the affected limb is warm, blood circulation is improved; limb numbness and pain are relieved. the
3、无效:病症无变化。 3. Ineffective: no change in symptoms.
临床实验时,停服其它药物和保健营养品。服用本发明具体实施方式2制作的中药胶囊,观察6个月,为一个疗程。服用方法:每日2次,每次4粒胶囊,每粒胶囊内含中药细粉及提取物0.3克,饭后温开水送服,1个月后症状即有缓解,服用6个月后,症状明显改善。临床实验的26人中,显效13人,有效11人,无效2人,总有效率92.3%。 During the clinical trial, stop taking other medicines and health nutrition products. Take the Chinese medicine capsule that the specific embodiment of the present invention 2 makes, observe 6 months, be a course of treatment. Dosing method: 2 times a day, 4 capsules each time, each capsule contains 0.3 grams of traditional Chinese medicine fine powder and extract, take it with warm water after meals, the symptoms will be relieved after 1 month, and after 6 months of taking, Symptoms improved significantly. Among the 26 people in the clinical trial, 13 were markedly effective, 11 were effective, and 2 were ineffective, with a total effective rate of 92.3%.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631600A (en) * | 2012-03-31 | 2012-08-15 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic foot |
| CN102657802A (en) * | 2012-06-07 | 2012-09-12 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic feet |
| CN102671064A (en) * | 2012-05-11 | 2012-09-19 | 北京绿源求证科技发展有限责任公司 | Chinese medicine for treating diabetic feet |
Citations (1)
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| CN102114213A (en) * | 2010-12-13 | 2011-07-06 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic acral necrosis |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102114213A (en) * | 2010-12-13 | 2011-07-06 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic acral necrosis |
Non-Patent Citations (2)
| Title |
|---|
| 范冠杰等: "糖尿病足中医诊疗标准", 《世界中西医结合杂志》, vol. 6, no. 7, 28 July 2011 (2011-07-28), pages 618 - 625 * |
| 赵进喜等: "糖尿病足的中医综合治疗技术", 《药品评价》, 8 May 2010 (2010-05-08), pages 25 - 28 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631600A (en) * | 2012-03-31 | 2012-08-15 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic foot |
| CN102671064A (en) * | 2012-05-11 | 2012-09-19 | 北京绿源求证科技发展有限责任公司 | Chinese medicine for treating diabetic feet |
| CN102657802A (en) * | 2012-06-07 | 2012-09-12 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic feet |
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Application publication date: 20120328 |