CN103735693A - Traditional Chinese medicine preparation for treating liver-qi stagnation type dyspepsia - Google Patents

Traditional Chinese medicine preparation for treating liver-qi stagnation type dyspepsia Download PDF

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CN103735693A
CN103735693A CN201410034852.2A CN201410034852A CN103735693A CN 103735693 A CN103735693 A CN 103735693A CN 201410034852 A CN201410034852 A CN 201410034852A CN 103735693 A CN103735693 A CN 103735693A
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treatment
chinese medicine
stagnation
medicine preparation
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CN103735693B (en
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逄锦忠
王淑慧
李政
袁青
黄永文
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Jin Wei
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逄锦忠
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating liver-qi stagnation type dyspepsia. The preparation is prepared from the following raw medicines: 20-30 grams of purslane, 20-30 grams of asiatic pennywort herb, 20-30 grams of scorched hawthorn fruit, 20-30 grams of spreading hedyotis herb, 10-20 grams of hibiscus flower, 10-20 grams of lithospermum, 10-20 grams of poria cocos, 5-15 grams of red peony root, 5-15 grams of dried orange peel and 5-10 grams of liquorice. The traditional Chinese medicine preparation disclosed by the invention is mainly used for treating the liver-qi stagnation type dyspepsia; during the treatment, the preparation is orally taken twice a day, with one dose a day and 10 days a treatment course; the preparation generally takes effect in one treatment course and the disease can be cured after two or three treatment courses; and the preparation can be continued to be taken one or two treatment courses to consolidate the treatment effect. The traditional Chinese medicine preparation for treating the liver-qi stagnation type dyspepsia, disclosed by the invention has the advantages of remarkable treatment effect, no side effect and difficulty in relapse after cure.

Description

A kind of dyspeptic Chinese medicine preparation of caused by hepatic stagnation qi stagnation for the treatment of
Technical field
The present invention relates to a kind of dyspeptic Chinese medicine preparation of caused by hepatic stagnation qi stagnation for the treatment of
Background technology
Functional dyspepsia is digestive system commonly encountered diseases, frequently-occurring disease, take continue or repeated relapsing epigastrium distension, dull pain, early full, belch, acid regurgitation, anorexia, feel sick, vomiting, etc. syndrome be main clinical manifestation.The cause of disease of functional dyspepsia and pathogenesis are still not exclusively clear, most scholars think that this disease is due to many factors, now generally acknowledged that its main pathogenesis is that gastrointestinal motility obstacle, gastric acid secretion are abnormal, internal organs perception is irritated, and the effect of psychologic factors, dietary factor, helicobacter pylori infections and gut hormone etc. is still in exploration.The selection of functional dyspepsia Therapeutic Method is experimental, and there is no a kind of method or medicine has sure curative effect to all patients, also lacks objective reliable curative effect determinate standard.
Clinically, functional dyspepsia is the most common with caused by hepatic stagnation qi stagnation dyspepsia, and patient's main manifestations is gastral cavilty distension, attacks support and has a pain, and gastralgia connects the side of body, and belch is frequent, defecates not smooth, every because of the outbreak of emotional factors pain, thin white fur of tongue, stringy pulse.Western medical treatment curative effect is undesirable, and side effect is larger, and traditional Chinese medical science symptomatic treatment has good curative effect.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of dyspeptic Chinese medicine preparation of caused by hepatic stagnation qi stagnation for the treatment of.
The present invention is achieved by the following technical solutions:
A kind of dyspeptic Chinese medicine preparation of caused by hepatic stagnation qi stagnation for the treatment of, by following crude drug, made: 20~30 grams of Herba Portulacaes, 20~30 grams of Herba Centellaes, 20~30 grams of Fructus Crataegi (parched to brown)s, 20~30 grams of Herba Hedyotidis Diffusaes, 10~20 grams of Flos Hibisci, 10~20 grams of Radix Arnebiae (Radix Lithospermi)s, 10~20 grams, Poria, 5~15 grams of Radix Paeoniae Rubra, 5~15 grams of Pericarpium Citri Reticulataes, 5~10 grams, Radix Glycyrrhizae.
Preferably, by following crude drug, made: 25 grams of Herba Portulacaes, 25 grams of Herba Centellaes, 25 grams of Fructus Crataegi (parched to brown)s, 25 grams of Herba Hedyotidis Diffusaes, 15 grams of Flos Hibisci, 15 grams of Radix Arnebiae (Radix Lithospermi)s, 15 grams, Poria, 10 grams of Radix Paeoniae Rubra, 10 grams of Pericarpium Citri Reticulataes, 8 grams, Radix Glycyrrhizae.
The preparation method of the dyspeptic Chinese medicine preparation of described treatment caused by hepatic stagnation qi stagnation is: get each crude drug, mix, add water to submerge, decoct to volume and be reduced to 1/2, filter to obtain medicinal liquid, be the dyspeptic Chinese medicine preparation for the treatment of.
The dyspeptic Chinese medicine preparation for the treatment of caused by hepatic stagnation qi stagnation of the present invention, cure mainly treatment caused by hepatic stagnation qi stagnation dyspepsia, during treatment, oral, twice of every day, potion every day (drug dose that preference provides is the amount of potion), 10 days courses for the treatment of, took effect in the general course for the treatment of, and can cure two or three courses for the treatment of, for consolidating curative effect, can continue to take one or two course for the treatment of.
The dyspeptic Chinese medicine preparation for the treatment of caused by hepatic stagnation qi stagnation of the present invention, therapeutic effect is remarkable, has no side effect, and after curing, is difficult for recurrence, and the raw materials used Chinese herbal medicine that is is gentle non-stimulated, and patient is easy to accept, and can apply.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated.
The dyspeptic Chinese medicine preparation of embodiment 1 preparation treatment caused by hepatic stagnation qi stagnation
Formula is: 25 grams of Herba Portulacaes, 25 grams of Herba Centellaes, 25 grams of Fructus Crataegi (parched to brown)s, 25 grams of Herba Hedyotidis Diffusaes, 15 grams of Flos Hibisci, 15 grams of Radix Arnebiae (Radix Lithospermi)s, 15 grams, Poria, 10 grams of Radix Paeoniae Rubra, 10 grams of Pericarpium Citri Reticulataes, 8 grams, Radix Glycyrrhizae.
Preparation method is: get each crude drug, mix, add water 1000ml, decoct to volume and be reduced to 500ml, filter to obtain medicinal liquid, be the dyspeptic Chinese medicine preparation for the treatment of.
During treatment, oral, every day twice, the amount of each about 250ml(potion every day), 10 days courses for the treatment of, in the general course for the treatment of, taking effect, can cure two or three courses for the treatment of, for consolidating curative effect, can continue to take one or two course for the treatment of.
The dyspeptic Chinese medicine preparation of embodiment 2 preparation treatment caused by hepatic stagnation qi stagnation
Formula is: 20 grams of Herba Portulacaes, 30 grams of Herba Centellaes, 20 grams of Fructus Crataegi (parched to brown)s, 30 grams of Herba Hedyotidis Diffusaes, 10 grams of Flos Hibisci, 20 grams of Radix Arnebiae (Radix Lithospermi)s, 10 grams, Poria, 15 grams of Radix Paeoniae Rubra, 5 grams of Pericarpium Citri Reticulataes, 10 grams, Radix Glycyrrhizae.
Preparation method is: get each crude drug, mix, add water 1200ml, decoct to volume and be reduced to 600ml, filter to obtain medicinal liquid, be the dyspeptic Chinese medicine preparation for the treatment of.
The dyspeptic Chinese medicine preparation of embodiment 3 preparation treatment caused by hepatic stagnation qi stagnation
Formula is: 30 grams of Herba Portulacaes, 20 grams of Herba Centellaes, 30 grams of Fructus Crataegi (parched to brown)s, 20 grams of Herba Hedyotidis Diffusaes, 20 grams of Flos Hibisci, 10 grams of Radix Arnebiae (Radix Lithospermi)s, 20 grams, Poria, 5 grams of Radix Paeoniae Rubra, 15 grams of Pericarpium Citri Reticulataes, 5 grams, Radix Glycyrrhizae.
Preparation method is: get each crude drug, mix, add water 1000ml, decoct to volume and be reduced to 500ml, filter to obtain medicinal liquid, be the dyspeptic Chinese medicine preparation for the treatment of.
The dyspeptic Chinese medicine preparation of embodiment 4 preparation treatment caused by hepatic stagnation qi stagnation
Formula is: 23 grams of Herba Portulacaes, 27 grams of Herba Centellaes, 23 grams of Fructus Crataegi (parched to brown)s, 27 grams of Herba Hedyotidis Diffusaes, 13 grams of Flos Hibisci, 17 grams of Radix Arnebiae (Radix Lithospermi)s, 13 grams, Poria, 12 grams of Radix Paeoniae Rubra, 7 grams of Pericarpium Citri Reticulataes, 9 grams, Radix Glycyrrhizae.
Preparation method is: get each crude drug, mix, add water 1000ml, decoct to volume and be reduced to 500ml, filter to obtain medicinal liquid, be the dyspeptic Chinese medicine preparation for the treatment of.
The dyspeptic Chinese medicine preparation of embodiment 5 preparation treatment caused by hepatic stagnation qi stagnation
Formula is: 27 grams of Herba Portulacaes, 23 grams of Herba Centellaes, 27 grams of Fructus Crataegi (parched to brown)s, 23 grams of Herba Hedyotidis Diffusaes, 17 grams of Flos Hibisci, 13 grams of Radix Arnebiae (Radix Lithospermi)s, 17 grams, Poria, 7 grams of Radix Paeoniae Rubra, 12 grams of Pericarpium Citri Reticulataes, 6 grams, Radix Glycyrrhizae.
Preparation method is: get each crude drug, mix, add water 1000ml, decoct to volume and be reduced to 500ml, filter to obtain medicinal liquid, be the dyspeptic Chinese medicine preparation for the treatment of.
Clinical data
Patient's data: 166 routine patients all suffer from caused by hepatic stagnation qi stagnation dyspepsia, is divided into two groups at random.Treatment group 83 examples, male's 47 examples wherein, women's 36 examples, at 21 years old~52 years old age, average 36 years old, the course of disease was the longest 4 years, the shortest 2 years; Matched group 83 examples, wherein male 45, women's 39 examples, at 20~52 years old age, average 36 years old, the course of disease was the longest 4 years, the shortest 2 years.Two groups of patient ages, sex, courses of disease, there are no significant for symptom comparing difference (P > 0.05), has comparability.
Diagnostic criteria: draft with reference to < < internal medicine handbook > > the 5th edition:
(1) upper abdominal pain, abdominal distention, early full, belch, feel sick, the symptom such as vomiting, in 12 months, symptom continues or duration of seizure accumulative total >=3 months repeatedly in the past;
(2) do not have these symptoms of possible explanation organic disease according to (comprising superior gastrointestinal endoscopy and other coherence checks etc.);
(3) symptom is not because defecation is alleviated, and the change of symptom generation and defecation frequency or character is irrelevant.
Therapeutic Method: treatment group adopts the medicine of embodiments of the invention 1 to treat, oral, every day twice, the amount of each about 250ml(potion every day), 10 days courses for the treatment of.Treat observe the curative effect after three courses for the treatment of.The oral domperidone of matched group 10mg/ time, every day 3 times; Losec 20mg/ time, every day 1 time, treats observe the curative effect after 30 days.
Criterion of therapeutical effect: < < functional dyspepsia therapeutic standards (draft) the > > passing through with reference to the 13rd meeting of calendar year 2001 Traditional Chinese Medicine association internal medicine the spleen-stomach disease Professional Committee drafts.For upper abdominal pain, big belly, early full, belch, the symptom such as feel sick are carried out rank scores:
Light: symptom is slight, do not affect work, life, be impatient at, remember 2 minutes.
In: symptom is heavier, has affected work, life, still can stand, and remembers 4 minutes.
Heavy: serious symptom, hinder one's work, live, endurable, remembers 6 minutes.
Asymptomatic, remember 0 minute.
According to the symptom integral before and after treatment, calculate therapeutic index, its formula is:
(the rear symptom integral of symptom integral-treatment before treating)/symptom integral * 100% before treating.
Clinical recovery: symptom disappears substantially, therapeutic index >=90%;
Effective: symptom obviously alleviates, therapeutic index >=30%-< 60%;
Invalid: symptom is without alleviating, and therapeutic index < 30%.
Therapeutic outcome: the routine patient for the treatment of group 83, recovery from illness 44 examples, effective 35 examples, invalid 4 examples, total effective rate 95.2%.The routine patient of matched group 83, recovery from illness 27 examples, effective 41 examples, invalid 15 examples, total effective rate 81.9%.

Claims (5)

1. treat the dyspeptic Chinese medicine preparation of caused by hepatic stagnation qi stagnation for one kind, it is characterized in that: by following crude drug, made: 20~30 grams of Herba Portulacaes, 20~30 grams of Herba Centellaes, 20~30 grams of Fructus Crataegi (parched to brown)s, 20~30 grams of Herba Hedyotidis Diffusaes, 10~20 grams of Flos Hibisci, 10~20 grams of Radix Arnebiae (Radix Lithospermi)s, 10~20 grams, Poria, 5~15 grams of Radix Paeoniae Rubra, 5~15 grams of Pericarpium Citri Reticulataes, 5~10 grams, Radix Glycyrrhizae.
2. the dyspeptic Chinese medicine preparation for the treatment of caused by hepatic stagnation qi stagnation according to claim 1, it is characterized in that: by following crude drug, made: 25 grams of Herba Portulacaes, 25 grams of Herba Centellaes, 25 grams of Fructus Crataegi (parched to brown)s, 25 grams of Herba Hedyotidis Diffusaes, 15 grams of Flos Hibisci, 15 grams of Radix Arnebiae (Radix Lithospermi)s, 15 grams, Poria, 10 grams of Radix Paeoniae Rubra, 10 grams of Pericarpium Citri Reticulataes, 8 grams, Radix Glycyrrhizae.
3. the dyspeptic Chinese medicine preparation for the treatment of caused by hepatic stagnation qi stagnation according to claim 1, it is characterized in that: by following crude drug, made: 23 grams of Herba Portulacaes, 27 grams of Herba Centellaes, 23 grams of Fructus Crataegi (parched to brown)s, 27 grams of Herba Hedyotidis Diffusaes, 13 grams of Flos Hibisci, 17 grams of Radix Arnebiae (Radix Lithospermi)s, 13 grams, Poria, 12 grams of Radix Paeoniae Rubra, 7 grams of Pericarpium Citri Reticulataes, 9 grams, Radix Glycyrrhizae.
4. the dyspeptic Chinese medicine preparation for the treatment of caused by hepatic stagnation qi stagnation according to claim 1, it is characterized in that: by following crude drug, made: 27 grams of Herba Portulacaes, 23 grams of Herba Centellaes, 27 grams of Fructus Crataegi (parched to brown)s, 23 grams of Hedyotidis Diffusaes, 17 grams of Flos Hibisci, 13 grams of Radix Arnebiae (Radix Lithospermi)s, 17 grams, Poria, 7 grams of Radix Paeoniae Rubra, 12 grams of Pericarpium Citri Reticulataes, 6 grams, Radix Glycyrrhizae.
5. the preparation method of the dyspeptic Chinese medicine preparation for the treatment of caused by hepatic stagnation qi stagnation described in claim 1~4, is characterized in that: get each crude drug, mix, add water to submerge, decoct to volume and be reduced to 1/2, filter to obtain medicinal liquid, be the dyspeptic Chinese medicine preparation for the treatment of.
CN201410034852.2A 2014-01-24 2014-01-24 One treats the dyspeptic Chinese medicine preparation of caused by hepatic stagnation qi stagnation Expired - Fee Related CN103735693B (en)

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