CN103721051A - Traditional Chinese medicine dispersible tablet for preventing HIV (Human Immunodeficiency Virus) and enhancing immunity and preparation method of traditional Chinese medicine dispersible tablet - Google Patents
Traditional Chinese medicine dispersible tablet for preventing HIV (Human Immunodeficiency Virus) and enhancing immunity and preparation method of traditional Chinese medicine dispersible tablet Download PDFInfo
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- CN103721051A CN103721051A CN201310700288.9A CN201310700288A CN103721051A CN 103721051 A CN103721051 A CN 103721051A CN 201310700288 A CN201310700288 A CN 201310700288A CN 103721051 A CN103721051 A CN 103721051A
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Abstract
The invention discloses a traditional Chinese medicine dispersible tablet for preventing HIV (Human Immunodeficiency Virus) and enhancing immunity and a preparation method of the traditional Chinese medicine dispersible tablet. The table is prepared from the following raw materials by weight: 10-15 parts of lycium chinense, 5-10 parts of Schisandra chinensis, 12-16 parts of Chinese olive, 15-20 parts of calendula officinalis, 10-15 parts of radix achyranthis bidentatae, 5-10 parts of Chinese lobelia, 10-15 parts of eucommia ulmoides, 5-10 parts of grangea maderaspatana, 10-15 parts of radix scrophulariae, 5-10 parts of polygonum multiflorum, 11-17 parts of penthorum chinense pursh, 10-15 parts of itea chinensis, 12-18 parts of poria cocos, 16-22 parts of codonopsis pilosula, 10-15 parts of rhizoma atractylodis macrocephalae, 18-24 parts of hance brandisia herb, 10-15 parts of tortoiseshell, 5-10 parts of the root of red-rooted salvia, 10-15 parts of astragalus membranaceus, 12-18 parts of root of common peony, 10-15 parts of ginseng leaf, 5-10 parts of gecko, 10-15 parts of earthworm, 5-10 parts of teasel root, 10-15 parts of rhizoma polygonati, 5-10 parts of radix puerariae, 10-15 parts of radix ophiopogonis, 5-10 parts of gynostemma pentaphylla, 10-15 parts of Chinese yam, 5-10 parts of paulownia leaf, 10-15 parts of lily, 12-16 parts of lucid ganoderma, 5-10 parts of radices trichosanthis and 4-7 parts of oleum morrhuae. The traditional Chinese medicine dispersible tablet is remarkable in inhibition effect on HIV, is capable of improving the organism immunity, alleviating clinical symptoms of patients, improving the living quality of the patients and prolonging the lives of HIV infected persons.
Description
Technical field
The dispersible tablets of Chinese medicine that the present invention relates to relate to a kind of anti HIV-1 virus, improves immunity, belongs to the field of Chinese medicines.
Background technology
Acquired immune deficiency syndrome (AIDS), i.e. acquired immune deficiency syndrome (AIDS), English name Acquired Immune Deficiency Syndrome, AIDS.The mankind because cause immunodeficiency after infecting HIV (human immunodeficiency virus) (Human Immunodeficiency Virus, HIV), concurrent a series of opportunistic infection and tumor, severe patient can cause dead syndrome.Because the Western medicine for the treatment of acquired immune deficiency syndrome (AIDS) is expensive and toxic and side effects is large, therefore find anti HIV-1 virus, the Chinese medicine that improves immunity of organisms becomes study hotspot.
Summary of the invention
In order to overcome the deficiencies in the prior art, the object of the present invention is to provide the dispersible tablets of Chinese medicine of a kind of anti HIV-1 virus, raising immunity, improve patient clinical symptom, improve life in patients, extend patient's life.
For achieving the above object, the present invention adopts following technical scheme:
A kind of anti HIV-1 virus, improve the dispersible tablets of Chinese medicine of immunity, raw material by following weight portion is made: Fructus Lycii 10-15, Fructus Schisandrae Chinensis 5-10, Fructus Canarii 12-16, Calendula officinalis 15-20, Radix Achyranthis Bidentatae 10-15, Herba Lobeliae Chinensis 5-10, Cortex Eucommiae 10-15, Herba Hyperici Japonici 5-10, Radix Scrophulariae 10-15, Radix Polygoni Multiflori 5-10, Penthorum chinense 11-17, Radix Ilicis Pernyi 10-15, Poria 12-18, Radix Codonopsis 16-22, Rhizoma Atractylodis Macrocephalae 10-15, Hance Brandisia Herb 18-24, Carapax et Plastrum Testudinis 10-15, Radix Salviae Miltiorrhizae 5-10, Radix Astragali 10-15, Radix Paeoniae Rubra 12-18, Folium Ginseng 10-15, Gecko 5-10, Pheretima 10-15, Radix Dipsaci 5-10, Rhizoma Polygonati 10-15, Radix Puerariae 5-10, Radix Ophiopogonis 10-15, Herb Gynostemmae Pentaphylli 5-10, Rhizoma Dioscoreae 10-15, Folium paulowniae 5-10, Bulbus Lilii 10-15, Ganoderma 12-16, Radix Trichosanthis 5-10, cod-liver oil 4-7.
Preferably, a kind of anti HIV-1 virus, improve the dispersible tablets of Chinese medicine of immunity, raw material by following weight portion is made: Fructus Lycii 15, Fructus Schisandrae Chinensis 10, Fructus Canarii 14, Calendula officinalis 18, Radix Achyranthis Bidentatae 10, Herba Lobeliae Chinensis 8, the Cortex Eucommiae 12, Herba Hyperici Japonici 8, Radix Scrophulariae 15, Radix Polygoni Multiflori 8, Penthorum chinense 14, Radix Ilicis Pernyi 12, Poria 16, Radix Codonopsis 18, the Rhizoma Atractylodis Macrocephalae 12, Hance Brandisia Herb 22, Carapax et Plastrum Testudinis 12, Radix Salviae Miltiorrhizae 8, the Radix Astragali 105, Radix Paeoniae Rubra 16, Folium Ginseng 15, Gecko 8, Pheretima 12, Radix Dipsaci 8, Rhizoma Polygonati 15, Radix Puerariae 8, Radix Ophiopogonis 10, Herb Gynostemmae Pentaphylli 8, Rhizoma Dioscoreae 10, Folium paulowniae 10, Bulbus Lilii 15, Ganoderma 14, Radix Trichosanthis 8, cod-liver oil 5.
A preparation method for the dispersible tablets of Chinese medicine of anti HIV-1 virus, raising immunity, comprises the following steps:
(1) get Radix Scrophulariae, Poria, Radix Puerariae, Ganoderma, Rhizoma Dioscoreae, Rhizoma Polygonati and Radix Astragali mix homogeneously, be ground into fine powder, sieve, standby;
(2) get the mixed mix homogeneously of Fructus Lycii, Fructus Schisandrae Chinensis, Radix Achyranthis Bidentatae, Herba Lobeliae Chinensis, Herba Hyperici Japonici, Radix Polygoni Multiflori, Penthorum chinense, Radix Ilicis Pernyi, Radix Codonopsis, Carapax et Plastrum Testudinis, Gecko, Pheretima and Herb Gynostemmae Pentaphylli, decoct with water secondary, add for the first time 4-8 times of water gaging, add for the second time 3-6 times of water gaging, each 1-3 hour that decocts, filters merging filtrate, be concentrated into appropriate, adding 75% ethanol, to make containing alcohol amount be 50-60%, and standing 24-36 hour, filters, filtrate is concentrated into the thick paste that relative density is 1.31-1.34, standby;
(3) get Fructus Canarii, Calendula officinalis, the Cortex Eucommiae, the Rhizoma Atractylodis Macrocephalae, Hance Brandisia Herb, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Folium Ginseng, Radix Dipsaci, Radix Ophiopogonis, Folium paulowniae, Bulbus Lilii mix homogeneously, add the water that 5-10 doubly measures, reflux 1-2h,, distillation, collects after first distillate, redistillation 0.5-1h, merge distillate, extract volatile oil, standby;
(4) in the thick paste that step (2) makes, add the fine powder that step (1) makes, volatile oil, Radix Trichosanthis, cod-liver oil and the appropriate dextrin that step (3) makes, mix homogeneously, granulates, dry, tabletting, and coating, gets product.
Usage and consumption: oral, a 3-5 sheet, 2-3 time on the one.
Beneficial effect of the present invention:
The all medicines of the present invention share have protect the liver, the kidney invigorating, enrich blood, QI invigorating, YANG invigorating, antiviral, improve immunity, profit joint, nourishing the lung to arrest cough, heat-clearing and toxic substances removing, invigorating the spleen and regulating the stomach, keep fit the multiple actions such as strong bone, HIV virus is had to significant inhibitory action, and improve immunity of organisms, improve patient clinical symptom, improve life in patients, extend HIV the infected's life.
The specific embodiment
A dispersible tablets of Chinese medicine for anti HIV-1 virus, raising immunity, is made by the raw material of following weight (g): Radix Codonopsis 15, Fructus Rosae Laevigatae 8, Semen Raphani 16, Caulis Cucurbitae 14, Herba Houttuyniae 22, Folium Kaki 12, Radix Polygalae 8, Herba Pogostemonis 12, Herba Menthae 8, Radix Glycyrrhizae 10, Folium Perillae 8, Flos Farfarae 15, Radix Asteris 11, Radix Peucedani 10, bodhi leaf 10, Bulbus Fritillariae Cirrhosae 16, Fructus Psoraleae 13, Fructus Momordicae 12, Radix ziziphi mauritianae 8, Radix Platycodonis 14, Poria 11, Semen Sterculiae Lychnophorae 12, Herb Gynostemmae Pentaphylli 8.
A preparation method for the dispersible tablets of Chinese medicine of anti HIV-1 virus, raising immunity, comprises the following steps:
(1) get Radix Scrophulariae, Poria, Radix Puerariae, Ganoderma, Rhizoma Dioscoreae, Rhizoma Polygonati and Radix Astragali mix homogeneously, be ground into fine powder, sieve, standby;
(2) get the mixed mix homogeneously of Fructus Lycii, Fructus Schisandrae Chinensis, Radix Achyranthis Bidentatae, Herba Lobeliae Chinensis, Herba Hyperici Japonici, Radix Polygoni Multiflori, Penthorum chinense, Radix Ilicis Pernyi, Radix Codonopsis, Carapax et Plastrum Testudinis, Gecko, Pheretima and Herb Gynostemmae Pentaphylli, decoct with water secondary, add for the first time 6 times of water gagings, add for the second time 4 times of water gagings, each decoction 2 hours, filters merging filtrate, be concentrated into appropriate, add 75% ethanol and make to be 60%, standing 36 hours, to filter containing alcohol amount, it is 1.32 thick paste that filtrate is concentrated into relative density, standby;
(3) get Fructus Canarii, Calendula officinalis, the Cortex Eucommiae, the Rhizoma Atractylodis Macrocephalae, Hance Brandisia Herb, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Folium Ginseng, Radix Dipsaci, Radix Ophiopogonis, Folium paulowniae, Bulbus Lilii mix homogeneously, add the water of 8 times of amounts, reflux 1.5h, distillation, collects after first distillate redistillation 1h, merge distillate, extract volatile oil, standby;
(4) in the thick paste that step (2) makes, add the fine powder that step (1) makes, volatile oil, Radix Trichosanthis, cod-liver oil and the appropriate dextrin that step (3) makes, mix homogeneously, granulates, dry, tabletting, and coating, gets product.
Usage and consumption: be decocted in water for oral dose, 1 dose of every day, minute 2-3 clothes.
The systematic treating of dispersible tablets of Chinese medicine of the present invention to acquired immune deficiency syndrome (AIDS), accumulated a large amount of clinical datas, up to the present, the case that has more complete case history to record is nearly thousand examples, in Chinese medicine examination, control aspect AIDS and gained most valuable experience, wherein most patients has all been adhered to the Chinese medicine of long term, and some patients were adheres to that Chinese traditional treatment reaches more than 10 years, existing as follows to recording more complete 729 routine brief summaries:
Case be calendar year 2001 January-2011 start the patient with Chinese traditional treatment year August, be hospital by case clinical and that laboratory is confirmed.All cases all carries out ELISA and checks that HIV antibody is positive before treatment, and some cases is repeatedly checked or further diagnosed through WB and PCR.Male's 267 examples in 729 routine patients, women's 462 examples, minimum is 7 years old, is 64 years old to the maximum.In 729 routine patients, during first visit, belong to silent HIV the infected 155 examples, symptomatic HIV the infected's 450 examples, AIDS person's 124 examples, 523 examples of being infected with malaria before treatment or in treatment, tuberculosis 54 examples, merge anemia 45 examples, hypertension 11 examples.Treatment is less than 1 year person's 300 example observing time, 1-3 person's 208 examples, 3-5 person's 131 examples, 5 years above person's 90 examples.
When first visit, there is the symptom that degree is different in 729 routine patients, its cardinal symptom comprises: weak 158 examples (62.8%), 233 examples of coughing (45.7%), erythra 313 examples (42.9%), 312 examples of generating heat (42.8%), large 173 examples of lymph node (23.7%), 128 examples of suffering from diarrhoea (17.5%), chest pain 96 examples (13.2%), skin 42 examples (5.7%) of itching, herpes zoster 42 examples (5.7%), 37 examples of having a headache (5.1%), spontaneous perspiration or night sweat person 37 examples (5.1%), indigestion and loss of appetite 35 examples (4.8%), aphtha 27 examples (3.7%), 22 examples of becoming thin (3.0%), arthralgia 14 examples (1.9%), other are as numb limbs and tense tendons, pudendal pruritus 6 examples, cardiopalmus 5 examples, skin infection furuncle and phyma 4 examples, 4 examples of suffering from abdominal pain, pharyngalgia 3 examples, menoxenia 2 examples, backache, lumbago, skelalgia, facial paralysis, distending pain of the breast.Patient is medical for cardinal symptom mainly with weak, cough, erythra, heating, lymphadenectasis, diarrhoea etc., take after dispersible tablets of Chinese medicine of the present invention patient's above-mentioned symptom be improved significantly, immunity of organisms significantly improves.
T lymphocyte subset group changes: patient's immune state when medical: have 722 routine patients to measure its CD4 counting, minimum is 0, be up to 1240, average out to 254.52 ± 157.10cell/ml, 666 examples have been carried out CD4/CD8 ratio measuring, it is minimum is 0, is up to 2.33, average out to: 0.37 ± 0.29.Wherein 542 examples have been carried out twice above immunologic function check, are respectively 262.03 ± 187.81 before treatment, check for the last time CD4 and are counted as 258.31 ± 217.76, and observed mean time is 18.65 ± 21.32 months.There are 507 examples to carry out front and back ratio calculation, are first: 0.392 ± 0.292, last check is 0.337 ± 0.315.
The relation of table 1CD4 classification and curative effect
As can be seen from Table 1, dispersible tablets of Chinese medicine tool of the present invention is significantly improved the effect of immunologic function, especially CD4 counting in reduced levels (<200) HIV sufferers, thereby improves patient clinical symptom, improve life in patients, extend HIV the infected's life.
Claims (3)
1. an anti HIV-1 virus, improve the dispersible tablets of Chinese medicine of immunity, it is characterized in that, raw material by following weight portion is made: Fructus Lycii 10-15, Fructus Schisandrae Chinensis 5-10, Fructus Canarii 12-16, Calendula officinalis 15-20, Radix Achyranthis Bidentatae 10-15, Herba Lobeliae Chinensis 5-10, Cortex Eucommiae 10-15, Herba Hyperici Japonici 5-10, Radix Scrophulariae 10-15, Radix Polygoni Multiflori 5-10, Penthorum chinense 11-17, Radix Ilicis Pernyi 10-15, Poria 12-18, Radix Codonopsis 16-22, Rhizoma Atractylodis Macrocephalae 10-15, Hance Brandisia Herb 18-24, Carapax et Plastrum Testudinis 10-15, Radix Salviae Miltiorrhizae 5-10, Radix Astragali 10-15, Radix Paeoniae Rubra 12-18, Folium Ginseng 10-15, Gecko 5-10, Pheretima 10-15, Radix Dipsaci 5-10, Rhizoma Polygonati 10-15, Radix Puerariae 5-10, Radix Ophiopogonis 10-15, Herb Gynostemmae Pentaphylli 5-10, Rhizoma Dioscoreae 10-15, Folium paulowniae 5-10, Bulbus Lilii 10-15, Ganoderma 12-16, Radix Trichosanthis 5-10, cod-liver oil 4-7.
2. anti HIV-1 virus according to claim 1, improve the dispersible tablets of Chinese medicine of immunity, it is characterized in that, raw material by following weight portion is made: Fructus Lycii 15, Fructus Schisandrae Chinensis 10, Fructus Canarii 14, Calendula officinalis 18, Radix Achyranthis Bidentatae 10, Herba Lobeliae Chinensis 8, the Cortex Eucommiae 12, Herba Hyperici Japonici 8, Radix Scrophulariae 15, Radix Polygoni Multiflori 8, Penthorum chinense 14, Radix Ilicis Pernyi 12, Poria 16, Radix Codonopsis 18, the Rhizoma Atractylodis Macrocephalae 12, Hance Brandisia Herb 22, Carapax et Plastrum Testudinis 12, Radix Salviae Miltiorrhizae 8, the Radix Astragali 105, Radix Paeoniae Rubra 16, Folium Ginseng 15, Gecko 8, Pheretima 12, Radix Dipsaci 8, Rhizoma Polygonati 15, Radix Puerariae 8, Radix Ophiopogonis 10, Herb Gynostemmae Pentaphylli 8, Rhizoma Dioscoreae 10, Folium paulowniae 10, Bulbus Lilii 15, Ganoderma 14, Radix Trichosanthis 8, cod-liver oil 5.
Anti HIV-1 virus as claimed in claim 1, improve the preparation method of the dispersible tablets of Chinese medicine of immunity, it is characterized in that comprising the following steps:
(1) get Radix Scrophulariae, Poria, Radix Puerariae, Ganoderma, Rhizoma Dioscoreae, Rhizoma Polygonati and Radix Astragali mix homogeneously, be ground into fine powder, sieve, standby;
(2) get the mixed mix homogeneously of Fructus Lycii, Fructus Schisandrae Chinensis, Radix Achyranthis Bidentatae, Herba Lobeliae Chinensis, Herba Hyperici Japonici, Radix Polygoni Multiflori, Penthorum chinense, Radix Ilicis Pernyi, Radix Codonopsis, Carapax et Plastrum Testudinis, Gecko, Pheretima and Herb Gynostemmae Pentaphylli, decoct with water secondary, add for the first time 4-8 times of water gaging, add for the second time 3-6 times of water gaging, each 1-3 hour that decocts, filters merging filtrate, be concentrated into appropriate, adding 75% ethanol, to make containing alcohol amount be 50-60%, and standing 24-36 hour, filters, filtrate is concentrated into the thick paste that relative density is 1.31-1.34, standby;
(3) get Fructus Canarii, Calendula officinalis, the Cortex Eucommiae, the Rhizoma Atractylodis Macrocephalae, Hance Brandisia Herb, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Folium Ginseng, Radix Dipsaci, Radix Ophiopogonis, Folium paulowniae, Bulbus Lilii mix homogeneously, add the water that 5-10 doubly measures, reflux 1-2h,, distillation, collects after first distillate, redistillation 0.5-1h, merge distillate, extract volatile oil, standby;
(4) in the thick paste that step (2) makes, add the fine powder that step (1) makes, volatile oil, Radix Trichosanthis, cod-liver oil and the appropriate dextrin that step (3) makes, mix homogeneously, granulates, dry, tabletting, and coating, gets product.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1245707A (en) * | 1999-08-12 | 2000-03-01 | 黄英秀 | Chinese medicine for curing AIDS and carcinomatosis |
| CN1363371A (en) * | 2002-01-11 | 2002-08-14 | 潘文光 | Multifunctional bio-active medicine for preventing and curing AIDS |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1245707C (en) * | 2000-09-12 | 2006-03-15 | 富士胶片株式会社 | Magnetic reproducing machine |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1245707A (en) * | 1999-08-12 | 2000-03-01 | 黄英秀 | Chinese medicine for curing AIDS and carcinomatosis |
| CN1363371A (en) * | 2002-01-11 | 2002-08-14 | 潘文光 | Multifunctional bio-active medicine for preventing and curing AIDS |
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