CN103720726A - Processing technology of folium ginkgo chewable tablets - Google Patents
Processing technology of folium ginkgo chewable tablets Download PDFInfo
- Publication number
- CN103720726A CN103720726A CN201310591621.7A CN201310591621A CN103720726A CN 103720726 A CN103720726 A CN 103720726A CN 201310591621 A CN201310591621 A CN 201310591621A CN 103720726 A CN103720726 A CN 103720726A
- Authority
- CN
- China
- Prior art keywords
- folium ginkgo
- ginkgo
- subnatant
- processing
- extracting solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
The invention relates to a processing technology of folium ginkgo chewable tablets, belongs to the field of food processing, and aims to develop a production technology which is safe, effective, scientific, concise and capable of realizing large-scale production. No chemical agent is added in the production process, the original flavor of folium ginkgo is maintained, ginkgolic acid harmful to the human body is not contained through deacidification treatment, and the tablets rich in natural ginkgolides and flavone are produced. The processing technology comprises the steps as follows: processing and extraction of folium ginkgo, addition of fillers, tabletting, pelleting and packaging.
Description
One, technical field
The present invention relates to a kind of processing technique of chewing gingko leaf tablet, belong to food processing field.
Two, background technology
Folium Ginkgo, Folium Ginkgo is the leaf of Ginkgoaceae plant Ginkgo biloba, nature and flavor sweetness and bitterness is puckery flat, the effects such as the useful heart is astringed the lung, removing dampness antidiarrheal.< < Chinese medicinal herbal > > records it can " gas of astringing the lung, relievings asthma and coughs, and leukorrhagia stopping is turbid ".According to modern pharmacological research, Folium Ginkgo is comparatively extensive to the effect of human body and animal body, as improves cardiovascular and peripheral vessels circulatory function, and myocardial ischemia is improved to effect, has the effect that promotes memory, improves brain function.In addition, can also reduce blood viscosity, remove free radical.Reduce cholesterol levels in blood of human body, prevent arteriosclerosis.Gingko leaf preparation and antidiabetic drug share treatment diabetes good therapeutic effect, can be used for the adjuvant of diabetes.Folium Ginkgo contains the useful ginkgetin of human body, lactone,, to reducing the effect of human free radical, reduction cholesterol, vessel softening, prevention of arterial thrombosis, is especially " three-hypers " crowd's desirable medical material.
The key issue that Folium Ginkgo develops is in all directions ginkgoic acid, and ginkgoic acid has potential sensitization, mutagenesis and cytotoxicity, so produce ginkgo leaf beverage, is to remove ginkgoic acid.Within 2005, Chinese Pharmacopoeia regulation Semen Ginkgo extrac ginkgoic acid content must be less than 10ppm.
The present invention be take Folium Ginkgo as raw material, through science, refines, processes, removes ginkgoic acid, makes chewing gingko leaf tablet easy to use, life-time service, one chew one chew between, fresh breath can improve blood capillary circulation simultaneously, removes human free radical, reduce cholesterol, useful health.
Three, summary of the invention
The object of the invention be intended to develop a kind of safe and effective, science succinct and the production technology of the chewing gingko leaf tablet that is produced on a large scale; production process is not added any chemical agent; the genuineness that keeps Folium Ginkgo; by disacidify, process not containing harmful ginkgoic acid, produce the chewable tablet that is rich in natural ginkgo lactone and flavone.Patent production technology of the present invention: the processing extraction of Folium Ginkgo, absorb fillers and tabletting pelletize packing.
Four, the specific embodiment
1. select the just young leaves of exhibition of blade face, ginkgo leaf powder is broken to 8 orders;
2. add 50-60 ℃, 10 times, water, heating and take out extracting solution after 1 hour; 3 times repeatedly; Extracting solution is cooling below 15 ℃, standing;
3. by the extracting solution of (step 2), first with 180 orders, filter, then 0.22 μ m draws Folium Ginkgo stock solution after filtering.
4. Folium Ginkgo stock solution obtained above is added to 99% ethanol, additional proportion is 1:5, stirring and dissolving;
5. by (step 4) extract adds extractor, adds alkanes substance, and additional proportion (1:5) is standing after mix homogeneously, removes upper strata liquid after layering, gets subnatant;
6. will (step 5) subnatant extracts 3 times repeatedly as step 2, gets subnatant;
7. by (Folium Ginkgo extract that must go out after ginkgoic acid after step 6) subnatant is dry, is rich in bilobalide and flavone.
8. absorb fillers: ginkgetin high-purity powder adds 400% microcrystalline Cellulose, mannitol, magnesium stearate and correctives filler, filler proportioning microcrystalline Cellulose, mannitol, magnesium stearate and correctives are 5:2:2:1, increase progressively dilution method and mix.
9. tabletting, pelletize and packing: by mixture after above-mentioned 8 absorb fillers, through modes such as extruding, fluid bed, tabletting or roll extrusion, sprayings, granulate, carry out tabletting processing granulating, adopt single dose blister formula aluminium foil press seal or the bottled mode of multiple dose to pack.
Claims (4)
1. the processing technique of a chewing gingko leaf tablet, it is characterized in that: the production technology of developing the succinct and chewing gingko leaf tablet that is produced on a large scale of a kind of safe and effective, science, production process is not added any chemical agent, the genuineness that keeps Folium Ginkgo, by disacidify, process not containing harmful ginkgoic acid, produce the chewable tablet that is rich in natural ginkgo lactone and flavone;
Patent production technology of the present invention: the processing extraction of Folium Ginkgo, absorb fillers and tabletting pelletize packing.
2. according to the method described in claims 1, it is characterized in that: the processing of described Folium Ginkgo is extracted and referred to: 1. select the just young leaves of exhibition of blade face, ginkgo leaf powder is broken to 8 orders; 2. add 50-60 ℃, 10 times, water, heating and take out extracting solution after 1 hour; 3 times repeatedly; Extracting solution is cooling below 15 ℃, standing; 3. by the extracting solution of (step 2), first with 180 orders, filter, then 0.22 μ m draws Folium Ginkgo stock solution after filtering;
4. Folium Ginkgo stock solution obtained above is added to 99% ethanol, additional proportion is 1:5, stirring and dissolving.
3. according to the method described in claims 1, it is characterized in that: it is that just above-mentioned 2 extract adds extractor that described Folium Ginkgo disacidify is processed, and adds alkanes substance, additional proportion (1:5), standing after mix homogeneously, after layering, remove upper strata liquid, get subnatant; Subnatant is extracted 3 times repeatedly as above-mentioned, get subnatant; The Folium Ginkgo extract that must go out after ginkgoic acid after subnatant is dry, is rich in bilobalide and flavone.
4. according to the method described in claims 1, it is characterized in that: described absorb fillers is that ginkgetin high-purity powder adds 400% microcrystalline Cellulose, mannitol, magnesium stearate and correctives filler, filler proportioning microcrystalline Cellulose, mannitol, magnesium stearate and correctives are 5:2:2:1, increase progressively dilution method and mix.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310591621.7A CN103720726A (en) | 2013-11-22 | 2013-11-22 | Processing technology of folium ginkgo chewable tablets |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310591621.7A CN103720726A (en) | 2013-11-22 | 2013-11-22 | Processing technology of folium ginkgo chewable tablets |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103720726A true CN103720726A (en) | 2014-04-16 |
Family
ID=50445188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310591621.7A Pending CN103720726A (en) | 2013-11-22 | 2013-11-22 | Processing technology of folium ginkgo chewable tablets |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103720726A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106758443A (en) * | 2016-12-09 | 2017-05-31 | 安徽农业大学 | A kind of ginkgo leaf edible packing paper of nontoxic high flavones content and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1813827A (en) * | 2005-02-04 | 2006-08-09 | 向云成 | Sea-buckthorn chewing tablet and its preparation |
| CN103169077A (en) * | 2011-12-26 | 2013-06-26 | 镇江市丹徒区南山溪园茶叶专业合作社 | Production process of gingko leaf capsule |
-
2013
- 2013-11-22 CN CN201310591621.7A patent/CN103720726A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1813827A (en) * | 2005-02-04 | 2006-08-09 | 向云成 | Sea-buckthorn chewing tablet and its preparation |
| CN103169077A (en) * | 2011-12-26 | 2013-06-26 | 镇江市丹徒区南山溪园茶叶专业合作社 | Production process of gingko leaf capsule |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106758443A (en) * | 2016-12-09 | 2017-05-31 | 安徽农业大学 | A kind of ginkgo leaf edible packing paper of nontoxic high flavones content and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104473249A (en) | Pine pollen liquid preparation and preparation method thereof | |
| CN1947757B (en) | Leave of glutinous rehmannia extractive, its preparation method and use, medicines prepared with said extractives | |
| CN106261447A (en) | A kind of hepatoprotective, the solid beverage alleviating discomfort after drinking and preparation method thereof | |
| CN104489674B (en) | A kind of composition and its preparation for alleviating exercise induced fatigue | |
| CN101007071A (en) | Traditional Chinese medicine for treating acute and chronic gastroenteritis and bacterial dysentery and its processing technology | |
| CN106822739A (en) | A kind of integration of drinking and medicinal herbs prevents and treats the particle of senile dementia | |
| CN103142916B (en) | Medicament for preventing and treating senile dementia and preparation method thereof | |
| CN103720726A (en) | Processing technology of folium ginkgo chewable tablets | |
| CN104474251B (en) | Composition and its preparation and the application of function are consolidated with brain tonic | |
| CN103719840A (en) | Processing technology of bamboo leaf flavonoid chewable tablets | |
| CN102579934B (en) | Traditional Chinese medical composition used for treatment of vascular dementia and preparation and application thereof | |
| CN105106156B (en) | A kind of preparation method for the Armillaria luteo-virens chewable tablets for improving sleep | |
| CN108578518A (en) | A kind of oral disnitegration tablet and preparation method thereof for drunk crowd | |
| CN103719869A (en) | Processing technology of pueraria flavonoid chewable tablet | |
| CN106963812A (en) | Application of the Herba Schizonepetae extract in antidepressant is prepared | |
| CN105749104A (en) | Traditional Chinese medicine preparation capable of developing intelligence and preparation method thereof | |
| CN103070842B (en) | Preparation method of miglitol sustained release tablet | |
| CN103169124A (en) | Production process of gingko leaf beverage | |
| CN105381015A (en) | Traditional Chinese medicine composition with anti-depression function and preparation method thereof | |
| CN101015596A (en) | Chinese patent drug for curing angiocardiopathy and cerebrovascular disease and its preparing method | |
| CN103169077A (en) | Production process of gingko leaf capsule | |
| CN105995987B (en) | Apple dietary fiber ball and preparation method thereof | |
| CN103977354A (en) | Chinese medicinal extract with anti-depression effect and preparation method and application thereof | |
| CN104161791B (en) | It is a kind of to treat Chinese medicine composition of cervical and lumbar diseases and its preparation method and application | |
| CN104510958A (en) | Heart deficiency amnesia treating effervescent tablets |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140416 |