CN103705726B

CN103705726B - The anti-curing oncoma medicated tea of Chinese medicine cellular immunotherapy

Info

Publication number: CN103705726B
Application number: CN201310752163.0A
Authority: CN
Inventors: 车艳艳; 车利群
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-12-31
Filing date: 2013-12-31
Publication date: 2015-10-14
Anticipated expiration: 2033-12-31
Also published as: CN103705726A

Abstract

The anti-curing oncoma medicated tea of Chinese medicine cellular immunotherapy, it adopts following weight parts raw material of Chinese medicine to make: Radix Astragali 2.5-3.5, Radix Rehmanniae Preparata 2.5-3.5, Herba Taraxaci 1.6-2.4, Rhizoma Atractylodis Macrocephalae 1.6-2.4, Radix Saposhnikoviae 1.6-2.4, Fructus Lycii 1.6-2.4, Flos Chrysanthemi 0.8-1.4, Radix Ophiopogonis 0.8-1.4, Ramulus Uncariae Cum Uncis 0.8-1.4, Herba Hedyotidis Diffusae 1.6-2.4, Fructus Ligustri Lucidi 1.6-2.4, Cordyceps 1.6-2.4.The present invention promotes this yuan of patient and immunity of organisms by conditioning, and the various misery that alleviation disease is brought and side effect, the traditional Chinese medical science cellular immunotherapy of general one-period, the tumor body of patient will keep stablizing and occurring atrophy.

Description

The anti-curing oncoma medicated tea of Chinese medicine cellular immunotherapy

Technical field

The invention belongs to human drugs technical field, the medicated tea of the anti-curing oncoma particularly made with natural material.

Background technology

According to the report of World Health Organization (WHO) (WHO), world's tumor incidence is now in the stage of constantly increasing, and anticipates that the annual neopathy number of cases of the year two thousand twenty will reach 1,500 ten thousand.In China, malignant tumor has occupied the first place of common cause of death.Due to the complexity of diagnosing tumor and the limitation of current diagnosis level, be especially middle and advanced stage when the quite a lot of patient of developing country makes a definite diagnosis, lost the opportunity of curative therapy.The defect of tumor traditional remedies: 1, perform the operation.Tumor patient often immunity is poor, even if be unwilling to do operative treatment, be often also difficult to recover, bring out cancerous cell on the contrary and breed quickly.And same often need of ocal resection tissue excises a part of normal structure, may cause postoperative certain sequela and dysfunction.2, chemicotherapy.Though chemicotherapy actuating quantity can be destroyed or eliminate cancerous cell, also damage normal cell simultaneously, cause toxic and side effects.The poison of chemicotherapy invades human body, and cause patient's immunity of organisms to decline, health is weaker, thus reduce the sensitivity of human body to chemicotherapy, the curative effect causing chemicotherapy treatment to produce is lower, so higher actuating quantity can only be used to be tackled, and the circulation that so just formation one is fatal.3, biological cell immunotherapy.Recent study confirms, tumor cell cannot by immunologically competent cell identification, kill and wound, owing to there is dendritic cell (DC) functional defect and rare numbers in tumor patient body, make it effectively cannot offer tumor antigen, cannot remove identification, killing tumor cell by activated T cell, this is the basic reason of malignancy of tumor growth.Biological immune cell therapy is also known as CIK/DC cellular immunotherapy.Being a kind of emerging, tumor treatment model with significant curative effect, is the anticancer novel method for the treatment of of a kind of autoimmune.It is the method fed back to after using biotechnology to carry out In vitro culture and amplification to the immunocyte gathered in patient body in patient body, excites, enhancing body autoimmune function, thus reaches the object for the treatment of tumor.Tumor biotherapy is the fourth-largest oncotherapy technology after operation, radiation and chemotherapy.But this technology requirements of operation is high, and the cycle is long, expense also general tumor patient can not be born.

Summary of the invention

The traditional Chinese medical science is along with modern medical mode is by the transformation of biomedical model to Bio-psycho-social Medical Mode, the treatment thoughts of tumor is no longer the pursuit elimination of simple mechanical or reduces tumor entity, killing off tumor cells, but consider the immunity of organism and mental symptom that improve patient simultaneously, improve this new health indicator of life quality.So along with the development of modern Chinese medicine immunology and traditional Chinese medical science Protocols in Molecular Biology, this theory of traditional Chinese medical science tumor immunotherapy climbs up the stage of New Times oncotherapy gradually.

Chinese medicine is thought, the raw marrow of kidney essense can hemopoietic, activating QI, vigour is burnt by three, spreading whole body, interior to zang-fu differentiation, reach podomere fur outward, become the important motivity maintaining bodily tissue organ normal configuration and the activity of excite tissue organ dysfunction, the bone marrow of visible modern medicine breeds kidney essense-vigour category that immune cell function belongs to the traditional Chinese medical science.Healthy energy foot then pathogen is difficult to occupy, if insufficiency of primordial QI, malicious heresy is easy to be detained in body and cause internal organs dysfunction, induces the pathological changes such as expectorant is turbid, blood stasis, turbid damp, pyretic toxicity, induces tumor heresy, therefore the vigour of body of answering a pager's call is evil in Qu Liuxiezhi road with tumor processed.According to the theory of above traditional Chinese medical science immunotherapy, the present invention adopts following raw material to make medicated tea:

Radix Astragali 2.5-3.5, Radix Rehmanniae Preparata 2.5-3.5, Herba Taraxaci 1.6-2.4, Rhizoma Atractylodis Macrocephalae 1.6-2.4, Radix Saposhnikoviae 1.6-2.4, Fructus Lycii 1.6-2.4, Flos Chrysanthemi 0.8-1.4, Radix Ophiopogonis 0.8-1.4, Ramulus Uncariae Cum Uncis 0.8-1.4, Herba Hedyotidis Diffusae 1.6-2.4, Fructus Ligustri Lucidi 1.6-2.4, Cordyceps 1.6-2.4.

The formula of preferential recommendation of the present invention is:

The Radix Astragali 3, Radix Rehmanniae Preparata 3, Herba Taraxaci 2, the Rhizoma Atractylodis Macrocephalae 2, Radix Saposhnikoviae 2, Fructus Lycii 2, Flos Chrysanthemi 1, Radix Ophiopogonis 1, Ramulus Uncariae Cum Uncis 1, Herba Hedyotidis Diffusae 2.Fructus Ligustri Lucidi 2, Cordyceps 2.

In this formula, Herba Hedyotidis Diffusae has cancerous cell and kills and wounds and inhibitory action, mildly bitter flavor; There is antipyretic and antidote functions simultaneously; The Radix Astragali, Fructus Lycii, Fructus Ligustri Lucidi, Cordyceps have regulating action to immune system, the Radix Astragali and Fructus Lycii sweet in the mouth, the micro-hardship of Fructus Ligustri Lucidi, the sweet temperature of Cordyceps, about Cordyceps, Fructus Lycii, Fructus Ligustri Lucidi, Flos Chrysanthemi, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae also have antimutagenic simultaneously; Cordyceps, Fructus Lycii and Radix Rehmanniae Preparata can also inducing apoptosis of tumour cell.Simultaneously the present invention adopt Radix Saposhnikoviae, the YUPINGFENG SAN tradition prescription of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, composition is called as Chinese medicine immunomodulator, has exterior deficiency spontaneous perspiration, susceptible ailment said due to cold or exposure; The wind and rain cold-damp impairment of the configuration, skin is withered.Perspiration and aversion to wind, complexion is white all of a sudden, and pale tongue with thin fur is white, floating and deficient pulse.Also empty people's space between skin and muscles is controlled not solid, susceptible ailment said due to cold or exposure.Full side has enhancing body immunity, and inducing bone marrow synthesis stem cell, impels thymus to secrete healthy T cell, thus find and kill cancerous cell, reach the effect of Therapeutic cancer.

The present invention traditional Chinese medical science QI invigorating blood stasis dispelling and consolidate righting the rule for the treatment of under, conditioning promotes this yuan of patient and immunity of organisms, the various misery that alleviation disease is brought and side effect, the traditional Chinese medical science cellular immunotherapy of general one-period, the tumor body of patient will keep stablizing and occurring atrophy.Start the immune system of human body self by the traditional Chinese medical science and discharge immune dispersing tumor cell, avoid outsidely cultivating that immunocyte purity is not high, the exogenous pollution that may occur, input time there is the situations such as rejection, treat safely, have no side effect.Traditional immunocyte collection, cultivation, input, patient through repeated multiple times wound and misery, will adopt traditional Chinese medical science cellular immunotherapy directly to mobilize human immunocyte's orientation to assemble tumor cell and kills, patient's no pain hurtless measure.Amplify immune system tumor body by herbal elite and assemble signal, immune dispersing tumor cell is gone directly patient's canceration focus, starts immunity and kill, finally under immune dispersing tumor cellular infiltration, tumor body gradually atrophy until dissipate.Invention formulation short treating period, instant effect, taking convenience.Safety has no side effect.

Detailed description of the invention

Formula 1: the Radix Astragali 2.5, Radix Rehmanniae Preparata 3.5, Herba Taraxaci 1.6, the Rhizoma Atractylodis Macrocephalae 2.4, Radix Saposhnikoviae 1.6 Fructus Lycii 2.4, Flos Chrysanthemi 0.8, Radix Ophiopogonis 1.4, Ramulus Uncariae Cum Uncis 0.8, Herba Hedyotidis Diffusae 2.4, Fructus Ligustri Lucidi 1.6, Cordyceps 2.4, weight is gram, traditional method is made, and is once used amount, daily twice.Mouthfeel micro-sweet but can not cause blood glucose raise (there is blood sugar reducing function for diabetes), be applicable to all groups and drink according to the method for making tea.

Formula 2: the Radix Astragali 3.5, Radix Rehmanniae Preparata 2.5, Herba Taraxaci 2.4, the Rhizoma Atractylodis Macrocephalae 1.6, Radix Saposhnikoviae 2.4, Fructus Lycii 1.6, Flos Chrysanthemi 1.4, Radix Ophiopogonis 0.8, Ramulus Uncariae Cum Uncis 1.4, Herba Hedyotidis Diffusae 1.6, Fructus Ligustri Lucidi 2.4, Cordyceps 1.6.Compound method is with formula 1.

Formula 3: the Radix Astragali 3, Radix Rehmanniae Preparata 3, Herba Taraxaci 2, the Rhizoma Atractylodis Macrocephalae 2, Radix Saposhnikoviae 2, Fructus Lycii 2, Flos Chrysanthemi 1, Radix Ophiopogonis 1, Ramulus Uncariae Cum Uncis 1, Herba Hedyotidis Diffusae 2.Compound method is with formula 1.

Invention medicated tea uses the routine clinical study information of all kinds of tumors 120 for the treatment of

1, clinical data

In June, 2004 ~ 2013 year inventor in an October place special outpatient clinic has accepted cancer patient 120 example for medical treatment, wherein man 51 example, female 69 example, 45 ~ 66 years old age, average 59.9 years old; Its 15 Lung cancer cases, mammary cancer 19 example, carcinoma of prostate 18 example, gastric cancer 21 example, the esophageal carcinoma 22 example, colorectal cancer 9 example, adrenal gland neoplasms 5 example, kidney 3 cancer, hepatocarcinoma 8 example.All observation case focuses have early stage transfer at adjacent tissue's organ, lymph, and daily life can be taken care of oneself, and the extensive transferrer of whole body is not at the row of observation.Wherein 102 examples were for implementing operation and chemicotherapy treatment, and also have 11 examples not have operative treatment, but have passed chemicotherapy treatment, other 7 examples did not take operation and chemicotherapy, just other cancer therapy drugs of oral mistake.

2, diagnostic criteria and curative effect judging standard

Diagnosing tumor standard: by the method for current conventional diagnostic tumor, comprises medical history analysis, lab testing (namely chemically examine), physical examination, imaging examination (comprise CT, B ultrasonic, Chest X-rays, MRI---nuclear magnetic resonance art, nuclear medicine), pathologic finding makes a definite diagnosis.

Criterion of therapeutical effect is according to the curative effect judging standard (working out for 1972) of national Chinese herbal treatment malignant tumor

(1) cure: symptom, objective determination positive sign disappear completely, recover certain work capacity, and Continuous Observation more than 3 years is without recidivist;

(2) clinical cure: symptom and the positive sign of objective determination disappear, and recover certain work capacity;

1 grade: Continuous Observation more than 1 year is without recidivist;

2 grades: Continuous Observation half a year to one is year without recidivist;

3 grades: Continuous Observation 2-6 month without recidivist.

(3) effective: symptom disappears substantially, cancer reduces over half, and other objective determination takes an evident turn for the better;

1 grade: observe not developing deeply person half a year more than;

2 grades: observe 2-6 month not developing deeply person.

(4) effective: symptom makes moderate progress, and focus is basicly stable, observes person more than month;

(5) invalid: symptom and objective determination without improvement, or only have short-term to improve, and deterioration person rapidly.

3, Therapeutic Method

According to Radix Astragali 2.5-3.5, Radix Rehmanniae Preparata 2.5-3.5, Herba Taraxaci 1.6-2.4, Rhizoma Atractylodis Macrocephalae 1.6-2.4, Radix Saposhnikoviae 1.6-2.4, Fructus Lycii 1.6-2.4, Flos Chrysanthemi 0.8-1.4, Radix Ophiopogonis 0.8-1.4, Ramulus Uncariae Cum Uncis 0.8-1.4, Herba Hedyotidis Diffusae 1.6-2.4, Fructus Ligustri Lucidi 1.6-2.4, Cordyceps 1.6-2.4(with gram metering), in above-mentioned formula range, ampoule is adjusted to patient condition, sign and body constitution, brew according to the way boiled water of making tea and drink, brew two bags every day.Take continuously and add up effect in 6 months later.Other cancer therapy drugs are cut out during taking medicated tea.

4, result statistics

After treating 6 months end cycles, physical examination, imaging examination, pathologic finding is adopted to carry out focus change before and after comparison therapy, change in conjunction with tcm diagnosis patient sign simultaneously, prove that patient's major part focus diminishes, pain obviously goes down, patient's body constitution is obviously strengthened, as original weak, appetite is poor, sleep is poor etc., and symptom all improves.As follows according to curative effect judging standard statistics:

(1) 2 examples are cured, 1 routine breast carcinoma, 1 routine gastric cancer.(2) clinical cure 13 example, wherein 1 grade of 3 example, 2 grade of 4 example, 3 grade of 6 example.(3) effective 35 examples:, wherein 1 grade of 16 example, 2 grade of 19 example.(4) effective 67 examples.(5) invalid 3 examples.Total effective rate 97.5%.

5, conclusion: the raw material of Chinese medicine that the present invention adopts palatability fabulous is mixed with medicated tea and drinks, taking convenience, is applicable to long-term drink, has better effect for cancer rehabilitation.

Claims

1. the anti-curing oncoma medicated tea of Chinese medicine cellular immunotherapy, is characterized in that adopting following weight parts raw material of Chinese medicine to make: Radix Astragali 2.5-3.5, Radix Rehmanniae Preparata 2.5-3.5, Herba Taraxaci 1.6-2.4, Rhizoma Atractylodis Macrocephalae 1.6-2.4, Radix Saposhnikoviae 1.6-2.4, Fructus Lycii 1.6-2.4, Flos Chrysanthemi 0.8-1.4, Radix Ophiopogonis 0.8-1.4, Ramulus Uncariae Cum Uncis 0.8-1.4, Herba Hedyotidis Diffusae 1.6-2.4, Fructus Ligustri Lucidi 1.6-2.4, Cordyceps 1.6-2.4.

2. the anti-curing oncoma medicated tea of Chinese medicine cellular immunotherapy according to claim 1, is characterized in that adopting following weight parts raw material of Chinese medicine to make: the Radix Astragali 3, Radix Rehmanniae Preparata 3, Herba Taraxaci 2, the Rhizoma Atractylodis Macrocephalae 2, Radix Saposhnikoviae 2, Fructus Lycii 2, Flos Chrysanthemi 1, Radix Ophiopogonis 1, Ramulus Uncariae Cum Uncis 1, Herba Hedyotidis Diffusae 2, Fructus Ligustri Lucidi 2, Cordyceps 2.