CN103655216A - Daily cow breast washing liquid and preparation method thereof - Google Patents

Daily cow breast washing liquid and preparation method thereof Download PDF

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Publication number
CN103655216A
CN103655216A CN201310683380.9A CN201310683380A CN103655216A CN 103655216 A CN103655216 A CN 103655216A CN 201310683380 A CN201310683380 A CN 201310683380A CN 103655216 A CN103655216 A CN 103655216A
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weight portion
dirt
washing liquid
daily
emulsion
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CN103655216B (en
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杜海峰
韩小波
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SHANGHAI CONSON BIOLOGICAL TECHNOLOGY Co Ltd
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SHANGHAI CONSON BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

The invention belongs to the field of fine chemical product pharmaceutics, and discloses a daily cow breast washing liquid and a preparation method thereof. The daily cow breast washing liquid comprises benzalkonium chloride, a surfactant, hydrogen peroxide, glycerinum and water. By compounding the surfactant and the benzalkonium chloride, the daily cow breast washing liquid can produce rich and exquisite foams which permeates the interior of dirt in a short time to collapse the dirt, and ensure that the dirt breaks away from the skin of the daily cow breast, in addition, the washing liquid goes deep into positions between pores and skin lines, so as to absorb and thoroughly clean the dirt, effectively removes various dirt on surfaces of the daily cow breasts, kills bacteria, and further enhances the sterilizing effect by combining the hydrogen peroxide. The daily cow breast washing liquid has the high dirt cleaning capacity and good sterilizing effect, does not have residues, is non-irritant to skin, does not affect the quality of raw milk, is particularly suitable for being used in pastures in a large proportion of regions or used by dairy farmers, and effectively protects the breast heath of daily cows. The preparation method is simple, the raw material is easy to get, and the daily cow breast washing liquid is suitable for large scale production.

Description

A kind of milch cow is washed emulsion and preparation method thereof
Technical field
The invention belongs to fine chemical product galenic pharmacy field, be specifically related to a kind of milch cow and wash emulsion and preparation method thereof.
Background technology
Milk is to have the very food of high nutritive value and physiological function, the important nutrients that wherein contains the necessary for human such as abundant lactoprotein, butter oil, lactose, mineral, vitamin, has the laudatory title of " improving food ", " the nurse mankind ", " white blood ".Milk is not only of fine quality, and inexpensive, in the situation that current its people's trophic level is also very low, greatly develops milk cattle cultivating and seems very necessary.The final purpose that milch cow produces is to give milk, and therefore protects cow breast most important.
In the feeding process of milch cow, breast inevitably touches various mucks, feedstuff and earthfill rockfill concrete riprap RCC, so cow breast surface easily grows a lot of microorganisms, these antibacterials can enter in raw milk on the one hand, and contaminated milk affects the quality of milk, on the other hand, open in the newborn hole of cow breast owing to milking, so antibacterial also easily enters cow breast, causes mastitis, have a strong impact on lactogenic function, cause lactation amount to reduce, milk physicochemical property also can change, Quality Down.Therefore, need to strengthen the environmental health of raising dairy cattle and milk before the cleaning of cow breast.
Traditional cow breast cleaning way is generally with clear water or napkin wiping before milking, and carry out disinfection, but the drawback of this mode is to remove thoroughly dirt and the kill bacteria on cow breast surface, cause while milking dirt or antibacterial to have the opportunity that enters raw milk, thereby directly cause raw milk bacterial population to raise, pollute raw milk.The pasture of most or dairy farmer use dip before and after milking.Yet common dip product, the ability of clean dirt is poor.When having various spot on cow breast, common dip product bactericidal effect will variation.This is that due to the package action of the spot on cow breast, the antibacterial that makes to ensconce in spot is protected simultaneously because spot can reduce the effect of sterilization component in common dipping product.
Summary of the invention
In view of this, the object of the invention is to the defect for prior art, provide a kind of clean dirt ability milch cow strong, that bactericidal effect is good to wash emulsion and preparation method thereof.
For realizing object of the present invention, the present invention adopts following technical scheme:
Milch cow is washed an emulsion, comprises following weight portion raw material:
Figure BDA0000436256080000021
Preferably, described surfactant is ionic surfactant.
Preferably, described surfactant is one or more in alkyl benzene sulphonate, Sodium Alcohol Ether Sulphate, amine oxide, sodium lauryl sulphate, α-sodium olefin sulfonate, alkylolamides.
The present invention also provides a kind of milch cow to wash the preparation method of emulsion.
A kind of milch cow is washed the preparation method of emulsion, hydrogen peroxide, 1 weight portion~12 weight portion glycerol and 5 weight portion~12 weight parts waters of getting the Benzalkonii Chloridum of 0.1 weight portion~1 weight portion, the surfactant of 1 weight portion~10 weight portion and 1 weight portion~10 weight portion mix, stir 0.5h~2h, standing 2h, obtains.
Milch cow of the present invention is washed emulsion and comprises Benzalkonii Chloridum, surfactant, hydrogen peroxide, G & W.Milch cow of the present invention washes in emulsion that surfactant and Benzalkonii Chloridum are composite can produce abundant, fine and smooth foam, in the short time, be penetrated into the inside of dirt, disintegrate dirt, make it depart from cow breast skin, go deep between pore and skin texture dirt absorption, thoroughly removing simultaneously, effectively remove the various dirts in cow breast surface, kill bacteria, be equipped with hydrogen peroxide and further strengthen bactericidal effect.Milch cow of the present invention washes that the clean dirt ability of emulsion is strong, bactericidal effect good, noresidue, non-stimulated to skin, and former milk quality, without impact, is suitable for pasture, most areas or dairy farmer and uses effective assurance cow breast healthy.Milch cow of the present invention washes that the preparation method of emulsion is simple to operate, and raw material is easy to get, and is applicable to large-scale production.
The specific embodiment
The embodiment of the invention discloses a kind of milch cow and wash emulsion and preparation method thereof.Those skilled in the art can use for reference content herein, suitably improve technological parameter and realize.Special needs to be pointed out is, all similar replacements and change apparent to those skilled in the artly, they are all deemed to be included in the present invention.Product of the present invention and method are described by preferred embodiment, related personnel obviously can be within not departing from content of the present invention, spirit and scope to product as herein described with method is changed or suitably change and combination, realize and apply the technology of the present invention.
For realizing object of the present invention, the present invention adopts following technical scheme:
Milch cow is washed an emulsion, comprises following weight portion raw material:
Figure BDA0000436256080000031
Milch cow of the present invention is washed emulsion and comprises Benzalkonii Chloridum, surfactant, hydrogen peroxide, G & W.
Wherein, Benzalkonii Chloridum belongs to non oxidizing bactericide, there is wide spectrum, efficient sterilization algae removal ability, can effectively control bacterium algae propagation and foundry loam growth in water, and there is the effect of peeling off of good foundry loam and certain dispersion, osmosis, have simultaneously certain deoil, deodorizing capability and corrosion inhibition.The Benzalkonii Chloridum that milch cow of the present invention is washed in emulsion can effectively be removed the various dirts such as cow breast surface muck, feedstuff and earthfill rockfill concrete riprap RCC, while kill bacteria, thus dirt and antibacterial on cow breast are removed thoroughly, guarantee that cow breast is healthy.
The consumption that milch cow of the present invention is washed Benzalkonii Chloridum described in emulsion is 0.1~1 weight portion.Being 1 weight portion in certain embodiments, is 0.5 weight portion in certain embodiments, is 0.1 weight portion in further embodiments.
Surfactant and Benzalkonii Chloridum that milch cow of the present invention is washed in emulsion are composite, the two Synergistic, produce abundant, fine and smooth foam, can be penetrated in the short time inside of dirt, disintegrate dirt, make it depart from cow breast skin, go deep between pore and skin texture, dirt being adsorbed, thoroughly being removed simultaneously, thereby effectively remove the various dirts in cow breast surface.
In some embodiments, surfactant of the present invention is ionic surfactant.
In certain embodiments, surfactant of the present invention is one or more in alkyl benzene sulphonate, Sodium Alcohol Ether Sulphate, amine oxide, sodium lauryl sulphate, α-sodium olefin sulfonate, alkylolamides.
The mixture that the weight ratio that is alkyl benzene sulphonate, alkylolamides and amine oxide in some specific embodiments is 3:2:1, the mixture that the weight ratio that is sodium lauryl sulphate, Sodium Alcohol Ether Sulphate and alkylolamides in some specific embodiments is 3:3:2, the mixture that the weight ratio that is α-sodium olefin sulfonate, Sodium Alcohol Ether Sulphate and amine oxide in some specific embodiments is 4:3:1.
The consumption that milch cow of the present invention is washed surfactant described in emulsion is 1~10 weight portion.Being 3 weight portions in certain embodiments, is 5 weight portions in certain embodiments, is 10 weight portions in further embodiments.
Hydrogen peroxide chemical formula is H 2o 2, its aqueous solution is commonly called as hydrogen peroxide, and outward appearance is colourless transparent liquid, is a kind of strong oxidizer.Milch cow of the present invention is washed the hydrogen peroxide in emulsion, can effectively kill cow breast surface bacteria, and it is less that described milch cow is washed the consumption of hydrogen peroxide described in emulsion, concentration is lower, it is short action time that described milch cow is washed emulsion simultaneously, only has 30s, can skin do not produced and be stimulated.
The consumption that milch cow of the present invention is washed hydrogen peroxide described in emulsion is 1~10 weight portion.Being 5 weight portions in certain embodiments, is 1 weight portion in certain embodiments, is 10 weight portions in further embodiments.
Glycerol has skin protection moisture-keeping function, and milch cow of the present invention is washed in emulsion and also contains micro-glycerol, can moisten cow breast skin, avoids often cleaning cow breast being caused to defat.
The consumption that milch cow of the present invention is washed glycerol described in emulsion is 1~12 weight portion.Being 2 weight portions in certain embodiments, is 10 weight portions in certain embodiments, is 5 weight portions in further embodiments.
Milch cow of the present invention is washed and in emulsion, also contains 5 weight portion~12 weight parts waters.Being 5 weight portions in certain embodiments, is 12 weight portions in further embodiments.Preferably, described water is deionized water.
Milch cow of the present invention washes in emulsion that surfactant and Benzalkonii Chloridum are composite can produce abundant, fine and smooth foam, in the short time, be penetrated into the inside of dirt, disintegrate dirt, make it depart from cow breast skin, go deep between pore and skin texture dirt absorption, thoroughly removing simultaneously, effectively remove the various dirts in cow breast surface, kill bacteria, be equipped with hydrogen peroxide and further strengthen bactericidal effect.Milch cow of the present invention washes that the clean dirt ability of emulsion is strong, bactericidal effect good, noresidue, non-stimulated to skin, and former milk quality, without impact, is suitable for pasture, most areas or dairy farmer and uses effective assurance cow breast healthy.
The present invention also provides a kind of milch cow to wash the preparation method of emulsion, for getting hydrogen peroxide, 1 weight portion~12 weight portion glycerol and 5 weight portion~12 weight parts waters of the Benzalkonii Chloridum of 0.1 weight portion~1 weight portion, the surfactant of 1 weight portion~10 weight portion and 1 weight portion~10 weight portion, mix, stir 0.5h~2h, standing 2h, obtains.
It is simple to operate that milch cow of the present invention is washed emulsion preparation method, and raw material is easy to get, and is applicable to large-scale production.Experiment shows, milch cow of the present invention is washed emulsion preparation method and makes that milch cow is washed emulsion low temperature, heat storage stability is qualified.
In order further to understand the present invention, below in conjunction with embodiment, the present invention is described in detail.
Embodiment 1:
Milch cow is washed an emulsion, comprises following weight portion raw material:
Figure BDA0000436256080000051
Described surfactant is the mixture that the weight ratio of alkyl benzene sulphonate, alkylolamides and amine oxide is 3:2:1.
Preparation method:
Get hydrogen peroxide, 2 weight portion glycerol and 5 parts by weight of deionized water of the Benzalkonii Chloridum of 1 weight portion, the surfactant of 3 weight portions and 5 weight portions and mix, stir 1h, standing 2h, obtains milch cow and washes emulsion.Low temperature, heat storage detect qualified stability.
Embodiment 2:
Milch cow is washed an emulsion, comprises following weight portion raw material:
Described surfactant is the mixture that the weight ratio of sodium lauryl sulphate, Sodium Alcohol Ether Sulphate and alkylolamides is 3:3:2.
Preparation method:
Get hydrogen peroxide, 10 weight portion glycerol and 5 parts by weight of deionized water of the Benzalkonii Chloridum of 0.5 weight portion, the surfactant of 10 weight portions and 1 weight portion and mix, stir 0.5h, standing 2h, obtains milch cow and washes emulsion.Low temperature, heat storage detect qualified stability.
Embodiment 3:
Milch cow is washed an emulsion, comprises following weight portion raw material:
Figure BDA0000436256080000062
Described surfactant is the mixture that the weight ratio of α-sodium olefin sulfonate, Sodium Alcohol Ether Sulphate and amine oxide is 4:3:1.
Preparation method:
Get hydrogen peroxide, 5 weight portion glycerol and 12 parts by weight of deionized water of the Benzalkonii Chloridum of 1 weight portion, the surfactant of 10 weight portions and 10 weight portions and mix, stir 2h, standing 2h, obtains milch cow and washes emulsion.Low temperature, heat storage detect qualified stability.
Embodiment 4: bactericidal effect experiment
Preparation experiment bacteria suspension, making its concentration is 1 * 10 8cfu/mL~5 * 10 8it is 1 * 10 that cfu/mL(reclaims clump count 7cfu/mL~5 * 10 7cfu/mL).
Experimental group (group B): get disinfection experiment sterile test tube, first add 0.5mL experiment bacteria suspension, add again the organic interfering material of 0.5mL, mix, put in 20 ℃ ± 1 ℃ water-bath after 5min, with aseptic straw, draw diluent 4.0mL injection that weight ratio that milch cow described in above-described embodiment 1 washes emulsion and water is 1:2 wherein, mix rapidly and timing immediately.Treat that experimental bacteria and milch cow wash emulsion and interact to each scheduled time 30s, draw respectively 0.5mL experimental bacteria and milch cow and wash emulsion mixed liquor and be added in 4.5mL nertralizer, mix.Each manages experimental bacteria and milch cow is washed emulsion mixed liquor after adding nertralizer effect 10min, draws respectively 1.0mL sample liquid, cultivates method of counting mensuration and deposits viable count, 2 plates of every pipe sample liquid inoculation by viable bacteria.When as more in the clump count of growing on flat board, can carry out after 10 times of dilutions of series, then carry out viable bacteria and cultivate counting.
Matched group (group A): replace milch cow to wash emulsion with standard hard water, carry out parallel laboratory test, as positive control.
All experiment samples are all cultivated in 37 ℃ of constant incubators, bacterial propagule is cultivated to 48h and observe final result, calculate and kill logarithm, the results are shown in Table 1.The computing formula of wherein killing logarithm is as follows:
The logarithm value (group A) of killing the average viable bacteria concentration of logarithm value (KL)=matched group (No)-the average viable bacteria concentration of experimental group logarithm value (group B) (Nx)
All kinds of killing bacteria logarithms of table 1
Antibacterial Escherichia coli Yeast Streptococcus
Killing bacteria logarithm ≥4 ≥4 ≥5
By milch cow described in the visible embodiment of the present invention 1 of table 1 result, wash emulsion bactericidal effect remarkable, killing bacteria logarithm value is all more than or equal to 4.
Embodiment 2 is similar to embodiment 1 with the bactericidal effect that milch cow described in embodiment 3 is washed emulsion, and bactericidal effect is remarkable, and killing bacteria logarithm value is all more than or equal to 4.
The explanation of above embodiment is just for helping to understand product of the present invention and method and core concept thereof.It should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention, can also carry out some improvement and modification to the present invention, these improvement and modification also fall in the protection domain of the claims in the present invention.

Claims (4)

1. milch cow is washed an emulsion, it is characterized in that, comprises following weight portion raw material:
Figure FDA0000436256070000011
2. milch cow is washed emulsion according to claim 1, it is characterized in that, described surfactant is ionic surfactant.
3. milch cow is washed emulsion according to claim 1, it is characterized in that, described surfactant is one or more in alkyl benzene sulphonate, Sodium Alcohol Ether Sulphate, amine oxide, sodium lauryl sulphate, α-sodium olefin sulfonate, alkylolamides.
4. a milch cow is washed the preparation method of emulsion, it is characterized in that, hydrogen peroxide, 1 weight portion~12 weight portion glycerol and 5 weight portion~12 weight parts waters of getting the Benzalkonii Chloridum of 0.1 weight portion~1 weight portion, the surfactant of 1 weight portion~10 weight portion and 1 weight portion~10 weight portion mix, stir 0.5h~2h, standing 2h, obtains.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106344491A (en) * 2016-11-09 2017-01-25 安徽永牧机械集团有限公司 Formula of breast cleaning liquid for dairy cattle
CN108379291A (en) * 2018-05-18 2018-08-10 新疆畜牧科学院兽医研究所(新疆畜牧科学院动物临床医学研究中心) A kind of cow uteri rinses formula of liquid and preparation method thereof

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101628006A (en) * 2008-07-14 2010-01-20 烟台绿叶动物保健品有限公司 Composition for disinfecting nipple skins of dairy cows

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101628006A (en) * 2008-07-14 2010-01-20 烟台绿叶动物保健品有限公司 Composition for disinfecting nipple skins of dairy cows

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
夏峥嵘 等: "《皮肤消毒剂的研究进展》", 《中华医院感染学杂志》, vol. 21, no. 8, 31 December 2011 (2011-12-31), pages 1716 - 1718 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106344491A (en) * 2016-11-09 2017-01-25 安徽永牧机械集团有限公司 Formula of breast cleaning liquid for dairy cattle
CN106344491B (en) * 2016-11-09 2019-01-18 安徽永牧机械集团有限公司 A kind of milk cow washes lotion
CN108379291A (en) * 2018-05-18 2018-08-10 新疆畜牧科学院兽医研究所(新疆畜牧科学院动物临床医学研究中心) A kind of cow uteri rinses formula of liquid and preparation method thereof

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