CN103651424A - Effervescent granule containing chlorantraniliprole and emamectin benzoate and preparation method thereof - Google Patents
Effervescent granule containing chlorantraniliprole and emamectin benzoate and preparation method thereof Download PDFInfo
- Publication number
- CN103651424A CN103651424A CN201210345894.9A CN201210345894A CN103651424A CN 103651424 A CN103651424 A CN 103651424A CN 201210345894 A CN201210345894 A CN 201210345894A CN 103651424 A CN103651424 A CN 103651424A
- Authority
- CN
- China
- Prior art keywords
- rynaxypyr
- benzoate
- emamectin
- selects
- granulae effervescentes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention discloses an effervescent granule containing chlorantraniliprole and emamectin benzoate. The effervescent granule is mainly applied to control of insect pests on crops. The composition comprises the effective components of 1-20% of chlorantraniliprole, 1-20% of emamectin benzoate, 2-10% of dispersing agent, 1-5% of wetting agent and 1-5% of stabilizer, and also comprises 0.5-20% of disintegrating agent, 5-20% of acid source, 5-20% of carbon dioxide gas source, 0.01-2% of binder and the balance of inert filler. The invention simultaneously discloses a preparation method of the effervescent granule. The method comprises the following steps: firstly, crushing raw materials into particles with the particle size of less than 10 microns by a jet mill, and mixing by a mixer; and simultaneously adding binder slurry, evenly mixing, and then drying and screening to prepare the effervescent granule by an effervescent pelletizer. The effervescent granule is free of pollution on environment, fast to disintegrate, accurate to meter and convenient to use. The insecticidal compound effervescent granule belongs to an environment-friendly pesticide, and is free of three wastes in production and convenient to use.
Description
Technical field
The present invention relates to formulations of pesticide technical field, be specifically related to a kind of Rynaxypyr first dimension salt granulae effervescentes and preparation method thereof.
Background technology
Rynaxypyr trade name health is wide, and chemical name is: the bromo-N-[4-chloro-2-methyl-6-[(of 3-methyl-carbamoyl) benzene]-1-(3-chloropyridine-2-yl)-1-hydrogen-pyridine-5-formamide, its structural formula is as follows:
The former medicine sterling of Rynaxypyr outward appearance is white crystals, proportion (liquid is required) 1.507g/mL, fusing point 208-210 ℃, 330 ℃ of decomposition temperatures, vapour pressure (20 ~ 25 times) 6.3 * 10
12pa, and solvability (20 ~ 25 times, mg/L): water 1.023, acetone 3.446, methyl alcohol 1.714, acetonitrile 0.711, ethyl acetate 1.144.Rynaxypyr belongs to O-formammidotiazol-benzamide insecticide.Because the chemical constitution of Rynaxypyr has the brand-new desinsection principle that other any insecticides do not possess, can efficiently activate insect ryania (muscle) acceptor.Calcium ion in excessive release cells in calcium storehouse, cause insect paralysis dead, larva activity to lepidoptera pest is high, insecticidal spectrum is wide, lasting effect is good, according to current result of the test, the specific activity other products of target pest is exceeded to 10-100 doubly. and can cause some lepidopterous insects mating process disorderly, studies have shown that it can reduce the spawning rate of multiple noctuidae pests.Show mammal and the extremely significant selective difference of the blue Buddhist nun's alkali of insect acceptor, greatly improved mammal and other vertebrate safeties.The maximum feature of Rynaxypyr is its novel mode of action, it acts on the ryanodine receptor (RyR) being present in insect bodies, there is structural difference in the ryanodine receptor in this acceptor and mammalian body, as what exist in human body, be three kinds of hypotypes of RyR, be RyR1, RyR2 and RyR3.Therefore this insecticide is very low to mammiferous toxicity.
Affirm (Merck Co.) benzoic acid is called for short first dimension salt, and chemical name is: 4'-table-methylamino-4'-deoxidation abamectin benzoate, and its structural formula is as follows:
The former medicine outward appearance of first dimension salt is white or light yellow crystalline powder, fusing point: 141 ℃ ~ 146 ℃; Stability: this product is stable under common storage requirement, unstable to ultraviolet light.Be dissolved in acetone, toluene, be slightly soluble in water, be insoluble to hexane.First dimension salt is to take fermented product AVERMECTIN B1 as raw material, a kind of semisynthetic antibiotics insecticides of producing through processes such as oxidation, amination, salifies, it can strengthen neurotransmitter as the effect of glutamate and a-aminobutyric acid (GABA), thereby make a large amount of chlorions enter nerve cell, cell function is lost, upset nerve conduction, larva stops feed at once afterwards in contact, there is irreversible paralysis and cause insect dead, in 3 ~ 4 days, reach the highest lethality rate.Due to it and soil in conjunction with closely, leaching not, in environment, do not accumulate yet, can be by the Translaminar transfer of moving, very easily absorbed by crops and be penetrated into epidermis, make dispenser crop have long-term residual effect, more than 10 days there is again second desinsection lethality rate peak, affected as wind, rain etc. by environmental factor.It has super-high-efficient, low toxicity (preparation is closely nontoxic), noresidue, the nuisanceless feature that waits biopesticide, with Avermectin first insecticidal activity improved 1 ~ 3 order of magnitude, activity to the larva of lepidopterous insects and other many insects and mite class is high, existing stomach poison function is double action of contace poison again, under low-down dosage (0.084 ~ 2g/ha), there is good effect, and in the process of pest control, beneficial insect is not injured, be conducive to the integrated control to insect, expanded in addition insecticidal spectrum, reduced the toxicity to people and animals.First dimension salt on protection ground or 10 times under recommendation dosage to all plant height safety.The a lot of insects of first dimension salt pair have the incomparable activity of other agricultural chemicals, especially to Lepidoptera, diptera, thrips class super-high-efficient, as red tape leaf roller, cigarette aphid noctuid, cotton bollworm, maduca sexta, diamond-back moth mythimna separata, beet armyworm, the greedy noctuid in nonirrigated farmland, confused Autographa spp, cabbage looper, imported cabbageworm, cabbage heart snout moth's larva, wild cabbage horizontal stripe snout moth's larva, tomato hawkmoth, colorado potato beetle, Mexico ladybug etc.Paddy rice is arrived to leaf-roller, rice silk worm first rice fulgorid thrips, the special efficacys such as vegetables diamond-back moth, cabbage caterpillar beet armyworm.
Along with the environmental consciousness that people strengthen day by day, governability authorities and user more emphasize to need exploitation and use safer, convenient, more effective under very low consumption, non-target kind is had to hypotoxicity and the formulation product more favourable to environmental protection.Therefore, the formulations of pesticide are developed towards high safety, environmental protection and cheap water base property preparation and non-dusting solid particulate preparation future development in the world.When granulae effervescentes is used, normally granula is dropped in dispense water, tablet produces a large amount of bubbles, makes tablet disintegration voluntarily, and under effect, make medicinal powder form uniform flushing liquor in being diffused into water voluntarily agitating of bubble, there is dispersion suspension in very high particle size and good water.Granulae effervescentes has the following advantages:
(1) do not use any organic solvent, in production, avoid inflammable, explosive and poisoning problem;
(2) meet a large amount of bubbles of water generates, rely on the inner motive force that produces gas of granula, make granula disintegration rapid, active ingredient diffusion farther, distribution more even, this is that water dispersible granules can not be compared;
(3) easy to use, can stand on ridge tablet is directly dropped into or be thrown into Tanaka, also can put into the sprayer being filled with water, thereby time and labour saving, without dust from flying, environmental pollution is little, uses safety;
(4) store transportation safety, packaged convenience;
(5) owing to there being thinner particle diameter than wetting powder, suspensibility and drug effect are higher than wetting powder.
Therefore, in the existing a large amount of kinds of developed country, put goods on the market in recent years.
Summary of the invention
The present invention is a kind of novel efficient agricultural compounded pesticides agent, in the present invention, said composition active ingredient is by Rynaxypyr 1 ~ 20%, first dimension salt 1 ~ 20%, dispersant 2 ~ 10%, wetting agent 1 ~ 5%, stabilizing agent 1 ~ 5%, also comprise in addition disintegrant 0.5 ~ 20%, acid source 5 ~ 20%, carbon dioxide air source 5 ~ 25%, adhesive 0.01 ~ 2%, inert filler surplus.
Preparation method of the present invention comprises the following steps:
(1) air-flow crushing: raw material is pulverized and obtained the following particle diameter of 10 μ m by airslide disintegrating mill;
(2) prepare binding agent slurry: with isopropyl alcohol or n-butanol, binding agent is broken into pasty state, and add mixer to mix with powder material;
(3) the granulation stage: with boiling granulator, forced air drying makes granulae effervescentes.
In order further to understand the present invention, existing in conjunction with the following example, the present invention will be described in more detail, but the present invention is not limited thereto.
embodiment 1
Take Rynaxypyr 5kg, emamectin-benzoate 2kg, dispersant Tersperse 2020 2kg, Borresperse NA 4kg, wetting agent modification sodium alkyl sulfate 4kg, stabilizing agent BHT 0.2kg, disintegrant ammonium sulfate 20kg, acid source sodium dihydrogen phosphate 12kg, carbon dioxide air source calcium carbonate 5kg, binding agent sodium carboxymethylcellulose 2kg, kaolin 43.8kg.Former medicine, dispersant, wetting agent, disintegrant, stabilizing agent, acid source, carbon dioxide air source, kaolin are pulverized and obtained the following particle diameter of 10 μ m by airslide disintegrating mill; With isopropyl alcohol, binding agent is broken into pasty state, and add mixer to mix with powder material; With boiling granulator, after forced air drying, screening 20 ~ 60 orders, obtain 7% Rynaxypyr first dimension salt granulae effervescentes.
embodiment 2
Take Rynaxypyr 10kg, emamectin-benzoate 3kg, dispersant Tersperse 2020 3kg, Borresperse NA 4kg, wetting agent modification sodium alkyl sulfate 4kg, stabilizing agent BHT 0.5kg, disintegrant ammonium sulfate 15kg, acid source sodium dihydrogen phosphate 12kg, carbon dioxide air source calcium carbonate 5kg, binding agent sodium carboxymethylcellulose 2kg, kaolin 41.5kg.Former medicine, dispersant, wetting agent, disintegrant, stabilizing agent, acid source, carbon dioxide air source, kaolin are pulverized and obtained the following particle diameter of 10 μ m by airslide disintegrating mill; With isopropyl alcohol, binding agent is broken into pasty state, and add mixer to mix with powder material; With boiling granulator, after forced air drying, screening 20 ~ 60 orders, obtain 13% Rynaxypyr first dimension salt granulae effervescentes.
embodiment 3
Take Rynaxypyr 15kg, emamectin-benzoate 5kg, dispersant Tersperse 2020 3kg, Tersperse 2700 3kg, wetting agent Morwet EFW 4kg, stabilizing agent BHT 1kg, disintegrant ammonium sulfate 10kg, acid source citric acid 17kg, carbon dioxide air source sodium bicarbonate 25kg, binding agent hydroxypropyl methylcellulose 1kg, talcum powder 16kg.Former medicine, dispersant, wetting agent, disintegrant, stabilizing agent, acid source, carbon dioxide air source, kaolin are pulverized and obtained the following particle diameter of 10 μ m by airslide disintegrating mill; With n-butanol, binding agent is broken into pasty state, and add mixer to mix with powder material; With boiling granulator, after forced air drying, screening 20 ~ 60 orders, obtain 20% Rynaxypyr first dimension salt granulae effervescentes.
embodiment 4
Take Rynaxypyr 20kg, emamectin-benzoate 5kg, dispersant Tersperse 2020 3kg, Tersperse 2700 5kg, wetting agent Morwet EFW 2kg, Terwet 1004 3kg, stabilizing agent BHT 1kg, disintegrant ammonium sulfate 10kg, acid source citric acid 17kg, carbon dioxide air source sodium bicarbonate 25kg, binding agent hydroxypropyl methylcellulose 1kg, talcum powder 11kg.Former medicine, dispersant, wetting agent, disintegrant, stabilizing agent, acid source, carbon dioxide air source, kaolin are pulverized and obtained the following particle diameter of 10 μ m by airslide disintegrating mill; With n-butanol, binding agent is broken into pasty state, and add mixer to mix with powder material; With boiling granulator, after forced air drying, screening 20 ~ 60 orders, obtain 25% Rynaxypyr first dimension salt granulae effervescentes.
Claims (9)
1. a Rynaxypyr emamectin-benzoate granulae effervescentes, is characterized in that comprising following composition and content (weight ratio):
Rynaxypyr 1 ~ 20%
Emamectin-benzoate 1 ~ 20%
Dispersant 2 ~ 10%
Wetting agent 1 ~ 5%
Stabilizing agent 1 ~ 5%
Disintegrant 0.5 ~ 20%
Acid source 5 ~ 20%
Carbon dioxide air source 5 ~ 25%
Binding agent 0.01 ~ 2%
Inert filler supplies 100%.
2. Rynaxypyr emamectin-benzoate granulae effervescentes as claimed in claim 1, is characterized in that described dispersant selects alkylphenol polyoxyethylene formaldehyde condensation products sulfonate, acrylic acid styrol copolymer if Tersperse 2700, Atlox Metasperse 550s, Geropon T/36, naphthalene sulfonate are if Tersperse 2020, Morwet D425, NNO, lignosulfonates are as one or more the combination in Borresperse NA, REAX 100M, Polyfon H etc.
3. Rynaxypyr emamectin-benzoate granulae effervescentes as claimed in claim 1, is characterized in that described wetting agent selects naphthalene sulfonate as one or more the combination in Morwet EFW, Terwet 1004, modified alkyl sulfate etc.
4. Rynaxypyr emamectin-benzoate granulae effervescentes as claimed in claim 1, it is characterized in that described stabilizing agent selects one or more the combination in BHT (BHT), butylated hydroxy anisole (BHA), sodium dihydrogen phosphate etc.
5. Rynaxypyr emamectin-benzoate granulae effervescentes as claimed in claim 1, is characterized in that described disintegrant selects one or more combinations in urea, ammonium sulfate, sodium sulphate, sodium chloride etc.
6. Rynaxypyr emamectin-benzoate granulae effervescentes as claimed in claim 1, is characterized in that described acid source selects one or more combinations in citric acid, tartaric acid, gallic acid, sodium dihydrogen phosphate, succinic acid, phosphoric acid, DBSA etc.
7. Rynaxypyr emamectin-benzoate granulae effervescentes as claimed in claim 1, is characterized in that described carbon dioxide air source selects one or more combinations in calcium carbonate, sodium carbonate, sodium bicarbonate, saleratus, potash etc.
8. Rynaxypyr emamectin-benzoate granulae effervescentes as claimed in claim 1, is characterized in that one or more combinations in described binding agent sodium carboxymethylcellulose, hydroxypropyl methylcellulose, polyvinyl alcohol, polyethylene glycol, aluminium-magnesium silicate etc.
9. Rynaxypyr emamectin-benzoate granulae effervescentes as claimed in claim 1, is characterized in that described inert filler selects one or more combinations in kaolin, calcined kaolin, diatomite, bentonite, talcum powder etc.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210345894.9A CN103651424A (en) | 2012-09-18 | 2012-09-18 | Effervescent granule containing chlorantraniliprole and emamectin benzoate and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210345894.9A CN103651424A (en) | 2012-09-18 | 2012-09-18 | Effervescent granule containing chlorantraniliprole and emamectin benzoate and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103651424A true CN103651424A (en) | 2014-03-26 |
Family
ID=50291140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210345894.9A Pending CN103651424A (en) | 2012-09-18 | 2012-09-18 | Effervescent granule containing chlorantraniliprole and emamectin benzoate and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103651424A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106942247A (en) * | 2017-04-21 | 2017-07-14 | 扬州大学 | Emamectin-benzoate effervescent tablet and preparation method thereof |
| CN110754475A (en) * | 2019-11-12 | 2020-02-07 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Medicament composition for preventing and treating spodoptera frugiperda and use method thereof |
| WO2021062338A1 (en) * | 2019-09-27 | 2021-04-01 | Fmc Corporation | Anthranilamide composition |
| CN112841210A (en) * | 2021-01-15 | 2021-05-28 | 上海生农生化制品股份有限公司 | Dispersing wetting agent composition |
| CN113508818A (en) * | 2021-08-12 | 2021-10-19 | 溧阳中南化工有限公司 | Pesticide for rice crops and preparation method thereof |
| US11944091B2 (en) | 2016-12-07 | 2024-04-02 | Adama Makhteshim Ltd. | Stable, self-dispersible, low foaming solid pesticide formulation |
-
2012
- 2012-09-18 CN CN201210345894.9A patent/CN103651424A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11944091B2 (en) | 2016-12-07 | 2024-04-02 | Adama Makhteshim Ltd. | Stable, self-dispersible, low foaming solid pesticide formulation |
| CN106942247A (en) * | 2017-04-21 | 2017-07-14 | 扬州大学 | Emamectin-benzoate effervescent tablet and preparation method thereof |
| WO2021062338A1 (en) * | 2019-09-27 | 2021-04-01 | Fmc Corporation | Anthranilamide composition |
| CN114430657A (en) * | 2019-09-27 | 2022-05-03 | Fmc公司 | Anthranilamide compositions |
| CN110754475A (en) * | 2019-11-12 | 2020-02-07 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Medicament composition for preventing and treating spodoptera frugiperda and use method thereof |
| CN112841210A (en) * | 2021-01-15 | 2021-05-28 | 上海生农生化制品股份有限公司 | Dispersing wetting agent composition |
| CN113508818A (en) * | 2021-08-12 | 2021-10-19 | 溧阳中南化工有限公司 | Pesticide for rice crops and preparation method thereof |
| CN113508818B (en) * | 2021-08-12 | 2022-05-17 | 溧阳中南化工有限公司 | Pesticide for rice crops and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103651424A (en) | Effervescent granule containing chlorantraniliprole and emamectin benzoate and preparation method thereof | |
| CN101709016B (en) | Sugarcane insecticide fertilizer and production method thereof | |
| CN102907424B (en) | Micro-capsule suspending agent containing pendimethalin | |
| EP2683247B1 (en) | An agrochemical composition comprising zinc, sulfur and a pesticidal active ingredient | |
| CN101422153A (en) | Insecticidal composition containing pymetrozine | |
| CN103651419A (en) | Chlorantraniliprole-emamectin benzoate suspending agent and preparation method thereof | |
| CN105010381B (en) | A kind of insecticides and its application containing Diacloden and emamectin benzoate | |
| CN108794175A (en) | A kind of organic fertilizer and preparation method thereof | |
| CN101817711A (en) | Emamectin benzoate-algae slow release type water dispersible granular insecticide and preparation method | |
| CN101176448B (en) | Bismerthiazol water dispersible granula bactericide and preparation method thereof | |
| CN100502660C (en) | Fruits protection effervescence tablets, preparation method and use thereof | |
| CN105746564B (en) | A kind of Pesticidal combination containing imidacloprid and dimehypo and its preparation method and application | |
| CN101361479A (en) | Water dispersion granule of methylamino avermectin benzoate and preparation method thereof | |
| CN101578038B (en) | Water soluble granule of spinosad and its preparation | |
| CN109430259A (en) | A kind of pesticide powder and preparation method thereof | |
| CN103858923B (en) | A kind of Pesticidal combination and application thereof containing Imidacloprid and gamma cyhalothrin | |
| CN102228044B (en) | Insecticidal composition containing sufluoxime | |
| CN101568256A (en) | Water soluble granule of chlorfenapyr and its preparation | |
| CN105010378B (en) | A kind of Pesticidal combination and its application containing Acetamiprid and emamectin benzoate | |
| CN104397030A (en) | Pesticide particulate agent containing humic acid and fipronil | |
| CN103598202A (en) | Insecticidal composition containing emamectin benzoate and efficient cyhalothrin | |
| CN101485329A (en) | Agricultural chemical composition for disinsection and use thereof | |
| CN102187868B (en) | Flubendiamide and emamectin benzoate blended emulsion and preparation method thereof | |
| CN104839194A (en) | Wheat seed treatment agent composition and application thereof | |
| CN101380018B (en) | Insecticidal composition containing thiacloprid and butene-fipronil |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140326 |