CN103637809B

CN103637809B - Needle assembly and blood collection assembly

Info

Publication number: CN103637809B
Application number: CN201310717276.7A
Authority: CN
Inventors: J·克劳福德; R·埃利斯; B·M·威尔金森; B·巴特费尔德; C·M·纽比; C·L·A·谭; J·莫; S·西姆; N·谢
Original assignee: Becton Dickinson and Co
Current assignee: Becton Dickinson and Co
Priority date: 2007-03-07
Filing date: 2008-03-07
Publication date: 2017-04-12
Anticipated expiration: 2028-03-07
Also published as: JP5558837B2; US10085680B2; EP4154815A3; AU2008222671B2; EP3108812A3; JP5799134B2; CA3006204A1; CN102178539B; CN101674772A; MX350738B; BRPI0808632A2; US20080319346A1; US10349880B2; EP3108811A1; JP2010520036A; JP2014208254A; US20110166476A1; CA3006204C; ES2939270T3; EP3100680A1

Abstract

A needle assembly is disclosed. The needle assembly includes a housing having a flash chamber, and having a distal end and a proximal end engageable with a specimen collection container. The assembly includes a cannula having a patient end, a non-patient end, and a sidewall extending therebetween defining a cannula interior. The patient end of the cannula projects at least partially from the distal end of the housing, and the cannula interior is in fluid communication with the flash chamber. The assembly further includes a shield restrainably engaged with a portion of the housing and axially transitionable over the patient cannula from a retracted position in which the patient end is exposed, to an extended position in which the patient end is shielded by at least a portion of the shield, wherein at least a portion of the flash chamber is visible when the shield is in the retracted position. The shield comprises a depending arm comprising a plurality of extendable segments, wherein the depending arm is oriented relative to the housing in a manner that the flash chamber is visible when the shield is in the retracted position. A blood collection assembly is further disclosed.

Description

A kind of needle assemblies and blood collection assembly

It is " have indicator for 200880014066.9, invention and created name that the present invention is Chinese invention patent application number Safety blood collection assembly ", the applying date be on March 7th, 2008（PCT/US2008/056264）Chinese invention patent application Divisional application.

For cross reference to related applications

Application claims are for the U.S. Provisional Application No.60/941,870 submitted on June 4th, 2007 and 2007 The U.S. Provisional Application No.60/893 that on March 7, in submits to, 519 priority, the complete disclosure of each application is by ginseng Kobo includes here.

Technical field

This patent disclosure relates generally to can protection safety needle assemblies, it is more particularly related to have housing, pin intubation and The needle assemblies of the sheath constraint engaged with a part for housing.

Background technology

Typical needle assemblies include pin intubation, and the pin intubation has near-end, sharp distal and the hole for extending between them Chamber, the sharp distal has puncture end.Thermoplasticity hub is usually fixedly secured on pin intubation to be spaced apart with distal end At position.Hub be typically provided with external screw thread or other for the surface structure that is installed to pin intubation in another structure.One A little needle assemblies are used for extracting sample, the such as sample of blood and other body fluid from patient.

For extracting the needle assemblies of the sample of blood and other body fluid, typically it is used in association with housing.With these The pin intubation that component is used in association with typically has sharp proximal and distal end, and needle hub disk is installed to the phase in pin intubation To on the position between two ends.Housing typically comprises generic tubular side wall, the tubular sidewall have very broadly unlimited near-end, With partially enclosed distal end.The hub of prior art needle assemblies can be engaged with the partially enclosed distal end of needle stand.Thus, pin intubation Sharpened proximal end reach in needle stand for evacuated tube（evacuated tube）Engage, and the sharp distal of pin intubation is to remote Place surmounts needle stand and stretches out, for the skin of puncture patient.

Needle assemblies are usually used together with sample collection pipe, for extracting the blood of patient and the sample of other body fluid.Examination Sample collecting pipe typically comprises blind end, open end and the side wall for extending between them.Pipe is typically drained, and opens Beginning is maintained at the vacuum in pipe by diaphragm seal, the barrier film.Evacuated tube is sized to, in sliding into the open distal end of needle stand. Evacuated tube makes the near-end of pin intubation pierce through the barrier film of evacuated tube into enough slips of needle stand.Thus, pin intubation can be set to The inside of evacuated tube is connected.

The needle assemblies and evacuated tube of combination in the blood vessel that the sharp distal of pin intubation is initially pushed patient by being used. Once coming into target blood, just evacuated tube is pushed in needle stand, so as to the far point of pin intubation pierces through the barrier film of pipe.In emptying The vascular system pressure of the low-pressure state and patient oneself in pipe, produces from patient by pin intubation and into evacuated tube Blood flow.After the blood for having collected q.s, evacuated tube can be removed from needle stand.One or more other emptyings Pipe can be pushed similarly in the open end of needle stand, for extracting one or more other blood samples to be analyzed.Right Collect after the blood of enough volumes in desired analysis process, pin intubation is just exited from the patient.In order to reduce idol The right acupuncture danger pricked or the contact that pathogen may be transmitted to doctor from patient, pin intubation must after contacting with patient Must be adequately shielded.

Polytype device is applied to the used pin intubation of shielding.Exemplary screening arrangement is included in United States Patent (USP) No.5,348,544；No.5,242,417；No.6,592,556；No.6,635,032；And that disclosed in No.7,001,363 A bit, the complete disclosure of these patents is incorporated herein by.Great majority shielding needle assemblies are in their master for completing Want function, that is, shield used pin intubation, aspect be effective.However, many doctors think these existing maskable pins Component is pretty troublesome.In addition, in some cases, doctor hastily and may forget safe operation sheath.Patient suddenly or Other situations can occur during accidental movement.Thus, pin intubation may accidentally pull out vein and expose, and blood-drawing doctor does not open The time of dynamic security mask.

It is related to ensure that vein enters the required time with regard to another problem of prior art blood collection device.Specifically Say, when entering in vein into intravenous or intubation distal end, blood will begin to flow through intubation.However, in intubation and Air present in multisample sleeve will prevent blood from flowing into and through intubation, and the multisample sleeve covers the non-patient of intubation End.Correspondingly, once doctor reasonably firmly believes comes in vein, doctor typically will push evacuated tube in needle stand. The rubber block of the end of evacuated tube will make the multisample colleting deformation in the non-patient end of intubation, and will allow intubation Non-patient end enter evacuated tube.Pressure reduction between evacuated tube and intubation will be such that blood flows in evacuated tube.In conventional needle group In part, this is usually provided suitably into the first visual confirmation of vein.

However, under many circumstances, doctor suitably with the distal end of pin intubation enters vein, but can be mistakenly considered also It is introduced into vein.So, doctor will enter to be advanced into second trial of vein.This addition is uncomfortable for patient, and prolongation is held The time that row blood collection procedure needs, and increase the brought into incidental contact between doctor and the intubation for being exposed to patient blood Danger.In addition, in some cases, passive screening mechanism will be activated when intubation is exited from the patient, and will thus insert pin Pipe is unavailable, and requires that doctor reuses a new needle assemblies.

The content of the invention

For the needs of such safety needle assembly exist：The safety needle assembly not only include visual streamer indicator but also Including safety shield, the safety shield can move to extended position from retracted position, in the retracted position, the end of pin intubation Exposure, in the extended position, shields the end of pin intubation, and this makes the exposure hazard minimum for medical worker, easy to use, And it is cost-effective.

In one embodiment of the application, needle assemblies include housing, and the housing has flash chamber, and housing has distal end And near-end, the near-end can engage with specimen collection container.Needle assemblies include intubation, and the intubation has the disease for limiting cannula interior People end, non-patient end and the side wall extended between patient end and non-patient end.The patient end of intubation is at least in part from housing Distal end stretch out, and cannula interior and flash chamber are in fluid communication.Needle assemblies also include being engaged with the part constraint of housing Sheath.Sheath can be axially moveable in patient's intubation from retracted position to extended position, in the retracted position, exposure Patient end, in the extended position, patient end is shielded by least a portion of sheath.At least a portion of flash chamber is being retracted It is visible in position.

At least a portion that flash chamber passes through the sheath in retracted position can be visible.In a kind of construction, The part of sheath is transparent or semitransparent, is visible by the part flash chamber.In another kind of construction, sheath includes Watch window, and flash chamber is visible by watch window in retracted position.The patient end of intubation can include oblique Face, and the position of the watch window in sheath can be corresponding with the orientation on inclined-plane.

In a kind of construction, the near-end of housing limits specimen collection container and receives port.Seal can be removed can be arranged In the part that specimen collection container receives port.Selectively, the seal that can split can be arranged in specimen collection container Receive in a part for port.

Sheath can at least partly surround the patient end of intubation in extended position.Optionally, sheath is substantially along week Arrange at least a portion around intubation, and sheath moves to extended position and makes sheath intussusception in intubation from retracted position Mobile (telescope).In certain embodiments, the side wall of intubation be limited between cannula interior and flash chamber extend open Mouthful.In other embodiments, intubation include at least two points of pin parts opened, such as with flash chamber fluid communication patient needle, And the non-patient pin being in fluid communication with flash chamber.Patient needle can stretch out at least in part from the distal end of housing, and non-disease People's pin can extend from patient's intubation along substantially proximal direction.In one embodiment, it is pieceable in the proximal end of housing Specimen collection container is blood collection container.

Flash chamber may be integrally formed in a part for housing.In some constructions, housing is slotting including support At least one of hub of pipe, and flash chamber is integrally formed with hub.Porous vent can be arranged in streamer chamber Interior, so as to flash chamber is separated into first chamber and second chamber by porous vent.First chamber and second chamber can be with It is configured to, when the patient end of intubation is inserted in patient body, blood is flowed by intubation, and is flowed in first chamber, And blow-by porous vent.Will emptying specimen collection container be applied in the non-patient end of intubation when, blood can be from the One chamber is extracted out, and air can extract out from second chamber, thus relative to flash chamber external environment condition in second chamber Interior formation negative pressure.Selectively, flash chamber can include the ventilating mechanism with the environmental communication around needle assemblies.Porous is ventilated Part can include multiple micropores, for blood Jing its from first chamber by second chamber.Ventilating mechanism can be by hydrophobic The porous plug that porous plug that material is formed, check valve or the water wetted material expanded during by with contacting blood are formed.

The masked segment of sheath constraint can be bonded in the interior section of housing in retracted position, and sheath Masked segment can stretch out in extended position from the interior section of housing.The interior section of housing can be wound in housing and limit Specimen collection container receive port circumferentially, and the interior section of housing can with specimen collection container receive port Coaxially.

Optionally, housing can include Part I and Part II, and Part I is in the distally of Part II.Sheath All can be arranged in the inside of Part I in retracted position, and specimen collection container receives port to be limited to In Part II.The Part I and Part II of housing can be collectively forming.Selectively, the Part I of housing and second Part can be separately formed, and be subsequently assembled.The Part I of housing can limit watch window, by the observation window Mouthful, sheath is visible when in retracted position.

In some constructions, when sheath is in retracted position, sheath can be by spring against a part for housing It is biased.Needle assemblies can also include that the releasing member of the second place can be moved to from first position, wherein working as releasing member When moving to the second place from first position, sheath is biased into extended position by spring.Releasing member can push button.Choosing Selecting property ground, pushes the part that button includes being oriented in generally vertically orientation relative to the mobile axis of sheath.Part can also Extended at least a portion of sheath, sheath was maintained in first position with overcoming the bias of spring.Part can also be wrapped Constraint portions are included, and passage area can be limited.Constraint portions can be bonded on the shoulder of the sheath in constrained, and When extended position is moved to from retracted position, the shoulder of sheath can pass through passage area.In a kind of construction, passage area Limit substantial circular opening.Selectively, passage area limits non-close region.Needle assemblies can also include support intubation At least one of hub, and push the part of button and can limit interior zone, the inner area at least partly surrounds hub A part for disk.

In another kind of construction, needle assemblies can also include that cannula guard can be removed, and this can remove cannula guard and housing It is a part of engageable, and can remove before sheath moves to extended position from retracted position.Cannula guard can be removed A part can prevent releasing member from moving to the second place from first position.In another kind of construction, the distal part of housing Blocking mechanism can be included with least one of the portions of proximal of sheath, for preventing sheath from moving to retraction from extended position Position.Blocking mechanism can include anti-interference flange.Blocking mechanism can also include locking tab, the locking tab sheath from Retracted position can bend when moving to extended position, once sheath is in extended position, the locking tab just substantially can not be scratched It is bent.A part of at least a portion that can surround locking tab of housing.Housing parts around locking tab can hinder substantially The only flexure of locking tab.

The sheath of needle assemblies can include Part I and Part II, and the Part I is used for the longitudinal axis along intubation A part for housing is sliding engaged, and the Part II at least partly surrounds a part for intubation in extended position. The Part I of sheath can be sliding engaged the outer surface of housing.In a kind of construction, the Part I of sheath includes projection, The projection is used for engaging slidably in the interior recessed groove of a part of the outer surface of housing.In another kind of construction, machine is slided Structure includes the part of housing and the part of sheath Part I, and a wherein part for safety shield can be relative to the one of housing Divide and be axially moveable.

Needle assemblies can also include the hub being at least partially disposed in housing parts, so as to the Part I edge of sheath The longitudinal axis of intubation is sliding engaged a part for hub.The first end of sheath Part I can be sliding engaged hub A part, and the second end of Part I can at least in part extend a part for housing outer surface.Part I Second end can at least in part extend the groove limited in the outer surface of housing, and the longitudinal axis along intubation prolongs Stretch.In another kind of construction, the Part II of sheath can surround at least a portion of intubation.

The sheath of needle assemblies by the power being applied to along the direction of the longitudinal axis of intubation on the Part I of sheath, Extended position can be moved to from retracted position.The Part II of sheath can also include constraint portions, for prevent sheath from Extended position moves to retracted position.

In a kind of construction, the Part II of sheath includes that the suspension arm of the second place can be moved to from first position, In the first position, suspension arm is substantially perpendicular with the longitudinal axis of intubation, and in the second place, suspension arm is substantially along slotting The longitudinal axis orientation of pipe.Suspension arm can include Part I and Part II, Part I and Part II pivotally or It is hingedly attached on Part I.Sheath can include suspension arm, and the suspension arm includes multiple extensible sections, wherein may extend away Section, substantially along transversal orientation, and is substantially longitudinally directed in retracted position in extended position.Between multiple extensible sections Can pivotally or hingedly be connected with each other.Suspension arm can be oriented on the first side of intubation, and the second suspension arm can be with It is oriented on the second side of intubation, the second side is substantially relative with the first side.

In another embodiment of the present invention, blood collection assembly includes housing, and the housing includes flash chamber, housing With proximally and distally and blood collection container seat, the blood collection container seat is adjacent with near-end.Blood collection assembly includes disease People's intubation, patient's intubation has cannula distal end, and limits patient's cannula interior.Patient's intubation is at least in part from housing Distal end is stretched out, and patient's cannula interior is in fluid communication with flash chamber.Blood collection assembly also includes non-patient intubation, and this is non- Patient's intubation limits non-patient cannula interior, from patient's intubation along substantially proximal direction at least the one of blood collection container seat Extend in part.Non-patient cannula interior is in fluid communication with flash chamber.Blood collection assembly also includes the part with housing The sheath for constraint engaging.Sheath can be axially moveable in patient's intubation from retracted position to extended position, in the retraction In position, patient end is exposed, in the extended position, cannula distal end is shielded by least a portion of sheath.Flash chamber is extremely A few part is visible in retracted position.

In retracted position, at least a portion that flash chamber passes through sheath is visible.Blood collection assembly can be with Including the seal that can remove or can split, the seal arrangement is at least a portion of blood collection container seat.In a kind of structure In making, sheath can be biased by spring in retracted position against a part for housing.Blood collection assembly can also be wrapped Including can move to the releasing member of the second place from first position, wherein moving to second from first position in releasing member When putting, sheath is moved to extended position by spring.Sheath can also include Part I and Part II, and the Part I is used for A part for housing is sliding engaged along the longitudinal axis of patient's intubation, and the Part II is at least part of in extended position A part of the ground around patient's intubation.

In yet another embodiment of the present invention, needle assemblies include housing, and the housing has flash chamber, and housing has remote End and the near-end that can be engaged with specimen collection container.Needle assemblies include intubation, and the intubation has the patient for limiting cannula interior End, non-patient end and the side wall extended between patient end and non-patient end.The patient end of intubation is at least in part from housing Distal end is stretched out, and cannula interior is in fluid communication with flash chamber.Needle assemblies also include constraint being engaged with a part for housing Sheath.Sheath can be axially moveable in patient's intubation from retracted position to extended position, in the retracted position, exposure Patient end, in the extended position, patient end is shielded by least a portion of sheath.At least a portion of flash chamber is being retracted It is visible in position.Needle assemblies also include spring element, and the spring element is in retracted position in the part and shield of housing It is biased between a part for set.Needle assemblies also include that the releasing member of the second place can be moved to from first position.About In beam position, releasing member overcomes the bias of spring to use restraint sheath, and releasing member moves to from first position Two positions cause sheath to move to extended position from retracted position.

Releasing member can push button.In some constructions, at least a portion of flash chamber is by retraction position A part for sheath in putting is visible.In other constructions, the near-end of housing includes blood collection container seat, and intubation Non-patient end extend at least in part in the inside of blood collection container seat.

In another embodiment of the present invention, blood collection assembly includes housing, and the housing includes flash chamber, housing With proximally and distally and blood collection container seat, the blood collection container seat is adjacent with near-end.Blood collection assembly includes disease People's intubation, patient's intubation has cannula distal end, and limits patient's cannula interior.Patient's intubation is at least in part from housing Distal end is stretched out, and patient's cannula interior is in fluid communication with flash chamber.Blood collection assembly also includes non-patient intubation, and this is non- Patient's intubation limits non-patient cannula interior.Non-patient intubation is from patient's intubation along substantially proximal direction in blood collection container Extend at least a portion of seat.Non-patient cannula interior is in fluid communication with flash chamber.Blood collection assembly also includes and shell The sheath that a part for body is constraint engaged.Sheath can vertically be moved in patient's intubation from retracted position to extended position It is dynamic, in the retracted position, cannula distal end is exposed, in the extended position, cannula distal end is shielded by least a portion of sheath. At least a portion of flash chamber is visible by the sheath in retracted position.Blood collection assembly also includes spring element Part, the spring element is biased in retracted position between a part for sheath and a part for housing.Blood collection assembly Also include pushing button, the pushing button is engaged with a part for spring, and can move to second from first position Put.When releasing member moves to the second place from first position, sheath is moved to extended position by spring.

In yet another embodiment of the present invention, blood collection assembly includes housing, and the housing has flash chamber, housing With distal end and the near-end that can be engaged with specimen collection container.Blood collection assembly includes intubation, and the intubation has to limit inserts Patient end, non-patient end inside pipe and the side wall extended between patient end and non-patient end.The patient end of intubation at least portion Ground is divided to stretch out from the distal end of housing, and cannula interior is in fluid communication with flash chamber.Blood collection assembly also includes sheath, should Sheath has watch window, and engages with a part for housing.Sheath can be moved to relative to housing from first position The second place, wherein sheath are arranged on patient end in the second position, and wherein at least a portion of flash chamber is By watch window it is visible in one position.

Sheath can be moved axially in intubation from retracted position to extended position.Selectively, sheath exists Can pivot movement from retracted position to extended position in patient's intubation.

In yet another embodiment of the present invention, blood collection assembly includes housing, and the housing has flash chamber, housing With distal end and the near-end that can be engaged with specimen collection container.Blood collection assembly includes intubation, and the intubation has to limit inserts Patient end, non-patient end inside pipe and the side wall extended between patient end and non-patient end.The patient end of intubation at least portion Ground is divided to stretch out from the distal end of housing, and cannula interior is in fluid communication with flash chamber.Blood collection assembly also includes sheath, should Sheath is engaged with a part for housing.Sheath can move to the second place relative to housing from first position.Flash chamber It is visible in first position, and sheath is arranged in the second position on the patient end of intubation.Latch-up structure is second At least a portion of flash chamber is engaged in position.In a kind of construction, the latch-up structure of sheath is bonded on the remote of flash chamber A part for the housing of side.

In one embodiment, the housing of needle assemblies includes foundation and hub portion, and the foundation has restriction The side wall of opening, the hub portion can be engaged with foundation.A part for hub portion can be accepted by opening. In another kind of construction, the side wall of foundation limits the first opening and the second opening along public affairs axis alignment altogether.Hub portion The Part I and Part II along public affairs axis alignment altogether can be included.Part I can be accepted by the first opening, And Part II can be accepted by the second opening.In another construction, hub portion can pass through foundation Near-end and be inserted within the inside of foundation.During hub portion is inserted into into foundation, Part I and At least one of two parts can bend against a part for the interior wall of foundation.

In another embodiment, the housing of needle assemblies includes forward hub portion and rear hub portion, the rear hub Disc portion can be connected with forward hub portion, and streamer chamber is limited between rear hub portion and forward hub portion Room.Rear hub portion can be connected by least a portion of specimen collection container seat with forward hub portion.May be selected Ground, rear hub portion can limit wherein specimen collection container and receive port.

Description of the drawings

Fig. 1 is the stereogram according to the needle assemblies of one embodiment of the present of invention, and the needle assemblies have in retracted position Safety shield.

Fig. 2 is the stereogram of the needle assemblies of Fig. 1, and the needle assemblies have the safety shield in extended position.

Fig. 3 is the amplification stereogram according to the pushing button member of the needle assemblies of one embodiment of the present of invention.

Fig. 4 is the amplification stereogram obtained from the part 4 of Fig. 2, is represented according to the safety protective of one embodiment of the present of invention The raceway groove of set.

Fig. 5 is the side view of the needle assemblies of Fig. 1, and the needle assemblies have the safety shield in retracted position.

Fig. 6 is the side view of the needle assemblies of Fig. 2, and the needle assemblies have the safety shield in extended position.

Fig. 7 is the sectional view of the needle assemblies of Fig. 1, and the needle assemblies have the safety shield in retracted position.

Fig. 8 is the sectional view of the needle assemblies of Fig. 2, and the needle assemblies have the safety shield in extended position.

Fig. 9 is the vertical view cutaway drawing of the needle assemblies of Fig. 1, with the safety shield in retracted position, and represent according to The locking mechanism of one embodiment of the present of invention.

Figure 10 is the vertical view cutaway drawing of the needle assemblies of Fig. 2, with the safety shield in extended position, and represents locking Mechanism.

Figure 11 is the stereogram according to the needle assemblies of another embodiment of the presently claimed invention, and the needle assemblies have flash chamber （flush chamber）.

Figure 12 is the rear perspective view of the needle assemblies of Figure 11, and the needle assemblies have flash chamber.

Figure 13 is the decomposition view of the needle assemblies of Figure 11, and the needle assemblies have flash chamber.

Figure 14 A are the sectional views of the needle assemblies of Figure 11, and the needle assemblies have flash chamber.

Figure 14 B are the amplification views of a part for the needle assemblies of Figure 14 A.

Figure 15 A are the sectional views according to the needle assemblies of another embodiment, and the needle assemblies have and blood collection assembly one The flash chamber that road is used.

Figure 15 B are the amplification views of a part for the needle assemblies of Figure 15 A.

Figure 16 is the stereogram according to the needle assemblies of one embodiment of the present of invention, and the needle assemblies have in retracted position Safety shield and needle cover.

Figure 17 is the stereogram of the needle assemblies of Figure 16, and the needle cover on the needle assemblies is removed, and with extended position In safety shield.

Figure 18 is the side view of the needle assemblies of Figure 16, and the needle assemblies have the safety shield in retracted position and carry Needle cover.

Figure 19 is the side view of the needle assemblies of Figure 17, and the needle cover on the needle assemblies is removed, and with extended position In safety shield.

Figure 20 is the side view cutaway drawing of the needle assemblies of Figure 16, the needle assemblies have the safety shield in retracted position and With needle cover.

Figure 21 is the side view cutaway drawing of the needle assemblies of Figure 17, and the needle assemblies remove needle cover, and with extended position In safety shield.

Figure 22 is the vertical view cutaway drawing of the needle assemblies of Figure 16, with the safety shield in retracted position, with needle cover, and And represent according to the locking mechanism of one embodiment of the present of invention.

Figure 23 is the vertical view cutaway drawing of the needle assemblies of Figure 17, removes needle cover, and with the safety in extended position Sheath, and represent locking mechanism.

Figure 24 is the stereogram of the needle assemblies of the present invention, and safety shield is removed for illustrative purposes, and including according to this The needle cover of one embodiment of invention.

Figure 25 is the sectional view of the needle assemblies of Figure 24.

Figure 26 is the stereogram of the seating portion of the needle assemblies of one embodiment of the present of invention, and the seating portion has and do not engaging Pushing button in retracted position.

Figure 27 is the stereogram of the seating portion for representing in fig. 26, and the seating portion has the pushing in engagement extended position Button.

Figure 28 is the stereogram of the one embodiment according to the pushing button of the present invention.

Figure 29 is the stereogram according to the needle assemblies of another embodiment of the presently claimed invention, and the needle assemblies have in retraction position Safety shield in putting.

Figure 30 is the stereogram of the needle assemblies of Figure 29, and the needle assemblies have the safety shield in extended position.

Figure 31 is the side view of the needle assemblies of Figure 29, and the needle assemblies have the safety shield in retracted position.

Figure 32 is the stereogram of the needle assemblies of Figure 30, and the needle assemblies have the safety shield in extended position.

Figure 33 is the vertical view cutaway drawing of the needle assemblies of Figure 29, and the needle assemblies have the safety shield in retracted position.

Figure 34 is the vertical view cutaway drawing of the needle assemblies of Figure 30, and the needle assemblies have the safety shield in extended position.

Figure 35 is the stereogram of Figure 29, represents the starting section of a part for needle stand.

Figure 36 is the stereogram of the pushing button of the needle assemblies represented in Figure 29.

Figure 37 is the stereogram of the needle assemblies of Figure 29, and the needle assemblies have according to the pin shield of one embodiment of the present of invention Set.

Figure 38 is the sectional view of the needle assemblies represented in Figure 29, and the needle assemblies have the removed intubation arranged thereon Shield.

Figure 39 is the stereogram according to the needle assemblies of one embodiment of the present of invention, and the needle assemblies have pushing press-button actuated Device, with removing cannula guard, this can remove the safety shield that cannula guard is covered with retracted position.

Figure 40 is the stereogram of the needle assemblies of Figure 39, can remove cannula guard and be removed, is illustrated in extended position Safety shield.

Figure 41 is the side view of the needle assemblies of Figure 39.

Figure 42 is the side view of the needle assemblies of Figure 40.

Figure 43 is the sectional view of the needle assemblies of Figure 39.

Figure 44 is the sectional view of the needle assemblies of Figure 40.

Figure 45 is the top view of the needle assemblies of Figure 39.

Figure 46 is the top view of the needle assemblies of Figure 40.

Figure 47 is the sectional view of the needle assemblies of Figure 39.

Figure 48 is the sectional view of the needle assemblies of Figure 40.

Figure 49 is the close up sectional view of the needle assemblies of Figure 47.

Figure 50 is the exploded perspective view of the needle assemblies of Figure 39.

Figure 51 is according to the partial perspective side figure of the locking tab of one embodiment of the present of invention.

Figure 52 is the partial perspective side figure of the locking tab of Figure 51, the locking tab and an enforcement according to the present invention Engage the housing parts of example.

Figure 53 is the exploded perspective view according to the needle assemblies of one embodiment of the present of invention.

Figure 54 is the part assembling stereogram of the needle assemblies of Figure 53.

Figure 55 is the part assembling stereogram of the needle assemblies of Figure 53.

Figure 56 is according to the optional exploded perspective view of the needle assemblies of one embodiment of the present of invention.

Figure 57 is the part assembling stereogram of the needle assemblies of Figure 56.

Figure 58 is the part assembling stereogram of the needle assemblies of Figure 56.

Figure 59 is the stereogram according to the needle assemblies of one embodiment of the present of invention, the needle assemblies have distally needle shield, With nearside needle shield.

Figure 60 is the top view of the hub component, distally needle shield and nearside needle shield of Figure 59.

Figure 61 is the cutaway top view of the needle assemblies of Figure 60.

Figure 62 is the side view of the needle assemblies of Figure 59.

Figure 63 is the sectional view of the side view of Figure 62.

Figure 64 is the stereogram of the needle assemblies of Figure 59, the needle assemblies and the sample collection according to one embodiment of the present of invention Container holder is engaged.

Figure 65 is the sectional side view of the needle assemblies in retracted position, and the needle assemblies have a reality according to the present invention Apply the optional locking mechanism of example.

Figure 66 is the sectional side view of the needle assemblies of Figure 65, and the needle assemblies are in extended position.

Figure 67 is the stereogram according to the needle assemblies of one embodiment of the present of invention, and the needle assemblies have in extended position Safety shield, and including coasting mechanism.

Figure 68 is the stereogram of the needle assemblies of Figure 67, and the needle assemblies have the safety shield in extended position.

Figure 69 is the side view of the needle assemblies of Figure 67, and the needle assemblies have the safety shield in retracted position.

Figure 70 is the side view of the needle assemblies of Figure 68, and the needle assemblies have the safety shield in extended position.

Figure 71 is the sectional view of the needle assemblies of Figure 69, and the needle assemblies have the safety shield in retracted position.

Figure 72 is the sectional view of the needle assemblies of Figure 70, and the needle assemblies have the safety shield in extended position.

Figure 73 is the exploded perspective view according to the needle assemblies of one embodiment of the present of invention, and the needle assemblies have can slide peace Full sheath.

Figure 74 is the exploded perspective view of the needle assemblies of Figure 73.

Figure 75 is the top view of the needle assemblies of Figure 73, and the needle assemblies are in assembling and retracted position.

Figure 76 is the cutaway top view of the needle assemblies of Figure 75, and the needle assemblies are in retracted position.

Figure 77 is the sectional side view of the needle assemblies of Figure 73, and the needle assemblies are in assembling and retracted position.

Figure 78 is the side view of the needle assemblies of Figure 77, and the needle assemblies are in retracted position.

Figure 79 is the top view of the needle assemblies of Figure 73, and the needle assemblies are in assembling and retracted position.

Figure 80 is the front view of the assembling needle assemblies of Figure 73.

Figure 81 is the rearview of the needle assemblies of Figure 80.

Figure 82 is the cutaway top view of the needle assemblies of Figure 76, and the needle assemblies are in extended position.

Figure 83 is the top view of the needle assemblies of Figure 82, and the needle assemblies are in extended position.

Figure 84 is the sectional side view of the needle assemblies of Figure 77, and the needle assemblies are in extended position.

Figure 85 is the side view of the needle assemblies of Figure 78, and the needle assemblies are in extended position.

Figure 86 is the upward view of the needle assemblies of Figure 79, and the needle assemblies are in extended position.

Figure 87 is the stereogram according to the needle assemblies of one embodiment of the present of invention, and the needle assemblies have in retracted position Hinged hinge safety shield.

Figure 88-90 is the stereogram of the needle assemblies of Figure 87, and the hinged hinge safety shield that the needle assemblies have prolongs in part Represent in each stage stretched.

Figure 91 is the stereogram of the needle assemblies of Figure 87, and the needle assemblies have the hinged hinge safety in fully extended position Sheath.

Figure 92 is the stereogram according to the needle assemblies of one embodiment of the present of invention, and the needle assemblies have in retracted position Butterfly hinge safety shield.

Figure 93 is the stereogram of the needle assemblies of Figure 92, and the needle assemblies have the butterfly hinge safety represented in extended position Sheath.

Figure 94 is the stereogram according to the needle assemblies of one embodiment of the present of invention, and the needle assemblies have hinge safety shield With pin protective jacket.

Figure 95 is the side view of the needle assemblies of Figure 94.

Figure 96 is the top view of the needle assemblies of Figure 94.

Figure 97 is the sectional side view of the needle assemblies of Figure 94.

Figure 98 is the stereogram of the needle assemblies of Figure 94, and the needle assemblies have pin protection shield removing and in retracted position Set.

Figure 99 is the side view of the needle assemblies of Figure 98.

Figure 100 is the top view of the needle assemblies of Figure 98.

Figure 101 is the sectional side view of the needle assemblies of Figure 98.

Figure 102 is the stereogram of the needle assemblies of Figure 98, and the needle assemblies are in extended position.

Figure 103 is the side view of the needle assemblies of Figure 102.

Figure 104 is the sectional view of the needle assemblies of Figure 102.

Figure 105 is the stereogram according to the safety shield of one embodiment of the present of invention and the engagement of forward hub portion.

Figure 106 is the close up of the engagement according to one embodiment of the present of invention between safety shield and forward hub portion Sectional block diagram.

Figure 107 is the exploded perspective view according to the needle assemblies of one embodiment of the present of invention, and there is the needle assemblies hinge to pacify Full sheath.

Figure 108 is the assembling stereogram of the needle assemblies of Figure 107, and the needle assemblies are in retracted position.

Figure 109 is the side view of the needle assemblies of Figure 108.

Figure 110 is the top view of the needle assemblies of Figure 108.

Figure 111 is the sectional side view of the needle assemblies of Figure 108.

Figure 112 is the front view of the needle assemblies of Figure 108.

Figure 113 is the rearview of the needle assemblies of Figure 108.

Figure 114 is the sectional side view of the needle assemblies of Figure 108.

Figure 115 is that, according to the optional decomposition view of the needle assemblies of one embodiment of the present of invention, the needle assemblies have hinge Chain safety shield.

Figure 116 is the stereogram of the needle assemblies of Figure 108, and the needle assemblies are in extended position.

Figure 117 is the stereogram of the needle assemblies of Figure 116, and the needle assemblies are in extended position.

Figure 118 is the sectional side view of the needle assemblies of Figure 116.

Figure 119 is the side view of the needle assemblies of Figure 116, and the needle assemblies are in extended position.

Figure 120 is the front view of the needle assemblies of Figure 116.

Figure 121 is the rearview of the needle assemblies of Figure 116.

Figure 122 is according to the optional hinge safety shield represented in extended position of one embodiment of the present of invention Partial perspective view.

Figure 123 is the stereogram according to the needle assemblies of one embodiment of the present of invention, the needle assemblies with sample container one Rise to have before use and can pierce seal.

Figure 124 is the stereogram of the needle assemblies of Figure 123, and the needle assemblies are in use.

Figure 125 is the stereogram of the needle assemblies of Figure 124, and the container of the needle assemblies is removed after usage from pierceable seal Go.

Figure 126 is the stereogram of the foundation of the housing according to the needle assemblies of one embodiment of the present of invention.

Figure 127 is the side view of the foundation of Figure 126.

Figure 128 is the stereogram of the hub portion of the housing according to the needle assemblies of one embodiment of the present of invention.

Figure 129 is the side view of the hub portion of Figure 128.

Figure 130 is the stereogram of the assembling housing of needle assemblies, and the assembling housing includes the foundation and Figure 128 of Figure 126 Hub portion.

Figure 131 is the side view of the assembling housing of Figure 130.

Specific embodiment

In general, needle assemblies of the invention are allowed by pin intubation into patient's vascular, into vascular system It is visual to indicate and subsequently to protect doctor security mask is carried out to pin intubation.

In one embodiment of the invention, there is provided needle assemblies 30, such as overall expression in figs. 1-10.Needle assemblies 30 generally comprise：Housing 32, with the flash chamber 38 with its one；Intubation 34, is associated with housing 32；And safety shield 36, it is suitable to from the retracted position for representing in FIG move to the extended position for representing in fig. 2, for making in needle assemblies 30 The security mask intubation 34 with during and/or after.Needle assemblies 30 are expressed as, in order in sample collection process（Such as blood collection mistake Journey）Used in and locate in retracted position in FIG, and after usage, the extended position of shielding intubation in fig. 2 In.

Particularly referring to Fig. 7-10, needle assemblies 30 include intubation 34, and the intubation 34 has distally patient end 40 and nearside non- Patient end 42.It will be noted that, term " distally " used herein above, the front end of general indicating hand component 30, the front end is suitable to puncture The skin of patient and the vascular system into patient, and the rear end of the general indicating hand component 30 of term " nearside ", the rear end and sample Collection vessel（Represent in Figure 123）It is pieceable.Intubation 34 includes side wall 48, and the side wall 48 is in patient end 40 and non-patient Extend between end 42, and limit cannula interior 50.In one embodiment, intubation 34 can include at least two points and open Pin, such as distally patient needle 52 and nearside non-patient pin 54, both is limited to a convenience center hole in cannula interior 50 Chamber.In a further embodiment, distally patient needle 52 is aligned substantially along common axis with nearside non-patient pin 54, and by disconnected Gap 56 is separated with nearside non-patient pin 54.The nearside non-patient end 42 of intubation 34 is to puncture specimen collection container（Represent in Figure 123 In）And set.In one embodiment, the nearside non-patient end 42 of intubation 34 can be by pierceable elastomer multisample sleeve 60 Cover.Distally patient end 40 can have inclined-plane, for allowing to be easier to penetrate patient skin.

The intubation 34 of needle assemblies can be supported at least in part by a part for housing 32.In one embodiment, housing 32 hubs 64 can with the part for support inserting tubes 34.For example, nearside non-patient pin 54 and distally patient needle 52 can To add or otherwise be bonded in the central opening 66 of hub 64, disconnected gap 56 is set to be present in nearside non-patient pin 54 and distally patient Between pin 52.In another kind of construction, hub 64 can be formed by the element for separating.For example, nearside or rear hub portion 68 Can be connected or be attached thereto with forward hub portion 70, thus hub 64 is formed as into overall structure, make intubation 34 Extend therethrough with.

As shown in Fig. 1-2 and 5-10, housing 32 can have distal end 74 and can be with specimen collection container（Represent in figure In 123）The near-end 72 of engagement.As used herein, phrase " can engage with specimen collection container " is it is meant that sample collection Container can link or be attached to a part for the near-end 72 of housing 32, or specimen collection container can be in the near-end of housing 32 Pass through in 72 part or be disposed thereon or around its arrangement, and be fixed on another part of housing 32.One In individual embodiment, the near-end 72 of needle assemblies 30 can limit specimen collection container and receive port 76, and the specimen collection container is received Port 76 is suitable to receive specimen collection container with it（Represent in Figure 123）.

In another embodiment, needle assemblies 30 are sample collection components, such as blood collection assembly, wherein needle assemblies 30 Housing 32 includes the specimen collection container seat 78 adjacent with the near-end 72 of needle assemblies 30.Specimen collection container seat 78 includes near-end 80th, distal end 82 and the tubular sidewall 84 that extends between them.In one embodiment, specimen collection container seat 78 can be wrapped Include the second tubular sidewall 86 circumferentially around tubular sidewall 84.The near-end 80 of specimen collection container seat 78 is at opening 88 Can be substantially unlimited, and may be adapted to receive specimen collection container wherein（Represent in Figure 123）.Near-end 80 also may be used With with radially aligned flange 90, in order to the manipulation of needle assemblies 30.Flange 90 can be non-circular, to prevent needle assemblies 30 Roll, or for other purposes, such as the design orientation of needle assemblies 30 is conveyed to into user.

Specimen collection container seat 78 is suitable at least a portion for accommodating intubation 34 with pair relationhip.For example, sample collection holds The distal end 82 of device seat 78 can include bonding part 92, a part for intubation 34, such as non-patient end 42, by one of hub 64 Divide and be installed on the bonding part 92.Specifically, the distal end 82 of specimen collection container seat 78 can include bonding part 92, should Bonding part 92 has pairing structure, is such as threadedly engaged, and is suitable to receive the rear hub portion 68 of hub 64.In one embodiment In, bonding part 92 may include screw thread 94, and the corresponding screw thread 96 for the rear hub portion 68 with hub 64 is engaged.Here It is also envisioned that to other pair relationhips, such as pairing male and female Luer (luer) assembly element.Hub 64 can also adhesively be attached to On the bonding part 92 of specimen collection container seat 78.In another embodiment, hub 64 with interference fit or can be engaged to examination In sample collection vessel seat 78.Selectively, hub 64 can be integrally formed with the distal end 82 of specimen collection container seat 78, there is provided For the mechanism being directly joined to intubation 34 on specimen collection container seat 78.In certain embodiments, intubation 34 is by manufacturer Engage with a part for specimen collection container seat 78, so as to device is ready to rapidly and easily be used by doctor.

In some constructions, the patient end 40 of intubation 34 stretches out at least in part from the distal end 74 of housing 32, and non-disease People end 42 extends along substantially proximal direction from patient end 40.In another embodiment, distally patient needle 52 is at least in part Stretch out from the distal end 74 of housing 32, and nearside non-patient pin 54 extends along substantially proximal direction from patient needle.

At least a portion of housing 32-include hub 64, the tubular sidewall 86 of specimen collection container seat 78 and second, including Flash chamber 98.As used herein, term " flash chamber " includes cavity, from the sample of patient, such as blood, can be with In leading to the cavity, and by it, the presence of sample in cavity can be detected visibly by doctor.Flash chamber 98 can be with Be integrally formed with a part for housing 32, or selectively, can be separately formed and later with one of housing 32 Split-phase is engaged.In one embodiment, cannula interior 50 is in fluid communication with flash chamber 98.In a further embodiment, intubation Side wall 48 can limit opening, the opening extends between cannula interior 50 and flash chamber 98, to allow sample, such as blood Liquid, from intubation 34 flash chamber 98 is flow to.In another embodiment, intubation 34 includes and the fluid communication of flash chamber 98 Distally patient needle 52 and the nearside non-patient pin 54 being in fluid communication with flash chamber 98.Correspondingly, when distally patient needle 52 is provided During into vascular system into patient, blood can be flowed by distally patient needle 52 from patient and flow into flash chamber 98 In.When nearside non-patient pin 54 and emptying specimen collection container（It is not shown）When engaging, blood can be logical from flash chamber 98 Cross the flowing of nearside non-patient pin.

In one embodiment, hub 64 can be included in a part and forward hub portion 70 for rear hub portion 68 A part between inside 100.Flash chamber 98 can be formed at least a portion of inside 100 of hub 64.One In kind of construction, hub 64, or at least a portion of hub 64, such as forward hub portion 70 can be by transparent or semitransparent materials Constitute, be such as made up of polymeric material or resin.Selectively, flash chamber 98 may be integrally formed in another portion of housing 32 In point, such as it is integrally formed with specimen collection container seat 78, or is formed in a part for the second tubular sidewall 86.

In use, streamer chamber will be entered by the opening 88 in intubation 34 by the blood flow of intubation 34 from patient Room 98, thus fills flash chamber 98 with blood part.Flash chamber 98 for doctor provide for recognize vein enter can Depending on mechanism.Exemplary flash back indicator（flushback indicator）In such as U.S. Patent Application Publication text Described in No.2005/0004524, the complete disclosure of the publication is incorporated herein by.

Needle assemblies 30 also include safety shield 36, and the safety shield 36 provides the shielding intubation 34 after the use of intubation 34 （Puncture end particularly at patient end 40）Mechanism.A part at least a portion of safety shield 36 and housing 32 is about Engage beam, and the retracted position that can be represented in Fig. 1,5,7 and 9 and the extension bit represented in Fig. 2,6,8 and 10 Move between putting.Safety shield 36 can between the retracted and extended positions be moved in a part for intubation 34.One In individual embodiment, safety shield 36 is axially movable in intubation 34.In a further embodiment, safety shield 36 can be Move axially between the retracted and extended positions in intubation 34, in the retracted position, at least expose the patient of intubation 34 The puncture end at end 40（Such as in order in patient body）, in the extended position, at least puncture of the patient end 40 of intubation 34 End is shielded by least a portion of safety shield 36.As used herein, phrase is " by least a portion of safety shield Shield " it is meant that the brought into incidental contact with the puncture end at the patient end 40 of intubation 34, by the patient end relative to intubation 34 At least one of position of 40 safety shields in shielding orientation prevents.In one embodiment, safety shield 36 is prolonging Stretch the patient end 40 that intubation 34 is at least partly surrounded or surrounded in position.

In one embodiment, as specifically represented in Fig. 5-10, in retracted position, safety shield 36 can To be arranged in the interior section 106 of housing 32, such as between the side wall 84 and second sidewall 86 of housing 32.For example, safety protective Set 36 can be arranged between side wall 84 and second sidewall 86, and the side wall 84 forms a part for specimen collection container seat 78, should Second sidewall 86 is arranged around side wall 84.Safety shield 36 can have any suitably sized and construction, so as to it is suitable to when safety Sheath 36 activated to extend to during extended position, shields the puncture end of the patient end 40 of intubation 34, as shown in Figure 2. In one embodiment, once the puncture end of the patient end 40 of intubation 34 removes from patient, it is possible to start safety shield 36 move from retracted position to extended position.In another embodiment, while intubation 34 is connected with patient body, such as exist While the patient end 40 of intubation 34 is in fluid communication with the vascular system of patient, can start safety shield 36 from retracted position to Extended position is moved.Correspondingly, the blood vessel of patient is going in intubation 34（It is not shown）Inside while, or in intubation After 34 remove from patient, safety shield 36 can stretch in intubation 34.If being going into patient's blood in intubation 34 While pipe inside, the movement from retracted position to extended position in safety shield 36, then the distal part of safety shield 36 there is 102 contact the skin with patient.

In one embodiment, safety shield 36 includes masked segment 104, and the masked segment 104 is in the longitudinal direction of intubation 34 On the direction of axis A（Represent in Figure 5）Can be axially moveable from retracted position to extended position.Masked segment 104 is in contracting Return can be constraint bonded in the interior section 106 of housing 32 in putting, and masked segment 104 can be with extended position Stretch out from the interior section 106 of housing 32.In one embodiment, axial movement of the sheath 36 from retracted position to extended position Masked segment 104 is existed at least in part from interior the moving to of interior section 106 of housing 32 substantially along the longitudinal axis A of intubation 34 Position outside housing 32.In another embodiment, the interior section 106 of housing 32 can be around specimen collection container seat 78 or examination Sample collection vessel receives port 76 circumferentially.In yet another embodiment, the interior section 106 of housing 32 holds with sample collection Device seat 78 or specimen collection container receive port 76 coaxial.As used herein, in the orientation that term " coaxial " includes, Interior section 106 and specimen collection container seat 78 or specimen collection container receive port 76 each around intubation 34 longitudinal axis A Arrangement.In a further embodiment, safety shield 36 is arranged around at least a portion of intubation 34, and safety shield 36 is from retraction Position moves to extended position intussusception mobile security sheath 36 in intubation in a part for intubation 34.Optionally, safety protective Set 36 can be around the generally peripheral arrangement of at least a portion of intubation 34.Here it is also envisioned that to safety shield 36 can include Intussusception movable part in single intubation, such as masked segment 104, or multiple nested sections circumferentially can be included, these are embedding Each is moveable in intubation 34 to cover section.

Safety shield 36 can be by moving to the releasing parts 108 of the second place from first position（Such as push button） And be extended.Releasing parts 108 are extensile by the outer surface 110 of safety shield 36 and housing 32.In an enforcement In example, releasing parts 108 can activate safety shield 36 and move to extended position from retracted position.In another embodiment, Releasing parts 108 can start actuator, and safety shield 36 is moved to into extended position from retracted position.Retouch in figs. 1-10 In the embodiment painted, releasing parts 108 include part 112, such as arm, mobile axis T of the part 112 relative to safety shield 36 （Represent in figure 6）Orient in generally vertically orientation.As used herein, phrase " mobile axis " is included in from retraction Position move to extended position during sheath orientation.In certain embodiments, longitudinal axis A pair of mobile axis and intubation 34 It is accurate.Part 112 may be coupled in constraint portions 114, such as amplify body, form passage area 116, such as narrow neck, such as Fig. 3 Shown in.In one embodiment, passage area 116 limits non-close region, such as cut channel or cut-out.Releasing parts 112 Constraint portions 114 also include the shoulder 118 adjacent with passage area 116.And, as shown in Figure 3, safety shield 36 includes Extended the elongated passageway 120 of sheath 36, with the amplification opening adjacent with before it or distal end, before formation and passage 120 The adjacent stop surfaces shoulder 122 in portion edge.In one embodiment, elongated passageway 120 passes through sheath 36 along its top surface Longitudinal extending.

With regard to the safety shield 36 in retracted position as shown in Figure 1, releasing parts 108 in first position, about Beam part 114 is extended in sheath 36, and the contiguous engagement of shoulder 118 of stop surfaces shoulder 122 and releasing parts 108, by This prevents safety shield 36 in the motion forward or in distal direction.When releasing parts 108, button is such as pushed, move away the During one position, such as it is pressed in the direction of arrow in figure 3, constraint portions 114 are relative to safety shield 36 substantially downward Move on direction, the contiguous engagement being thus released between stop surfaces shoulder 122 and shoulder 118.Like this, with elongated passageway The side wall 124 of 120 adjacent safety shields 36 can be directed to by the passage area 116 of without hindrance releasing parts 108, by This allows safety shield 36 that the extended position for representing in fig. 2 is moved to from the retracted position for representing in FIG.Correspondingly, release The constraint portions 114 for putting part 108 engage the stop surfaces shoulder 122 of sheath 36 in constrained, and in releasing parts From first position move to the second place and sheath 36 from constrained move to extended position when, the stop surfaces shoulder of sheath 36 The passage area 116 that portion 122 passes through releasing parts 108.

In one embodiment, safety shield 36 can be biased from spring 126 to extended position, and the spring 126 is arranged in Between a part for safety shield 36 and a part for housing 32.When sheath 36 is in retracted position, safety shield 36 can be with Biased from spring 126 to extended position.In one embodiment, spring 126 can be arranged in the portions of proximal of safety shield 36 Between 128 and the near-end 72 of housing 32.In another embodiment, as shown in figs. 7-10, spring 126 can be arranged in housing Between 32 side wall 84 and second sidewall 86.When releasing parts 108 move to the second place from first position, table in figure 3 Engagement show, between stop surfaces shoulder 122 and shoulder 118 is released, and spring 126 is biased into safety shield 32 Extended position, thus safely shields intubation 32.

As depicted in figs. 9-10, safety shield 36 is also provided with blocking mechanism 130, and the blocking mechanism 130 is configured to, and one Denier safety shield 36 moves to extended position from retracted position, just prevents safety shield 36 from moving to retraction from extended position Position.Correspondingly, blocking mechanism 130 prevent in intubation 34 by shielding after reentering in sheath 36 to housing 32 and The exposure of intubation 34.In this embodiment, at least one of the portions of proximal 128 of the distal end 74 of housing 32 and sheath 36 includes resistance Retaining device 130.In another embodiment, the portions of proximal 128 of the distal end 74 of housing 32 and sheath 36 all includes blocking mechanism 130。

Blocking mechanism 130 can include attaching means 132 and break part 134.Break part 134 can include oblique distal part 136 and portions of proximal 138, the portions of proximal 138 has a part of substantially perpendicular plane with safety shield 36.Break part 134 are sized to, when safety shield 36 moves to extended position from constrained, it is allowed to surmount by attaching means 132, this is about Bundle 132 is included in the distal end 74 of housing 32.The portions of proximal 138 of break part 134 is also sized to, once safety shield 36 Extended position is moved to from retracted position, safety shield 36 is just constrained against attaching means 132, to prevent safety shield 36 from passing through Attaching means 132.In another embodiment, releasing parts 108 can be constrained at least in part by a part for sheath 36, so as to Sheath 36 can not reset after extended position is moved to from retracted position.

As shown in Fig. 1,5,7 and 10, when safety shield 36 is in retracted position, flash chamber 98 is for doctor It is at least partly visible.In one embodiment, at least a portion of flash chamber 98 surmounts the safety protective in retracted position The distal part 102 of set 32 extends.In another embodiment, at least a portion of flash chamber 98 is by retracted position At least a portion of sheath 36 be visible.In another embodiment, at least a portion of sheath 36 is by translucent or saturating Bright material is made, and is visible by the part flash chamber 98.

As shown in Figure 11-15B, such as can be August in 2004 16 using flash chamber may be selected in the present invention U.S. Publication No.2006/0036219 of submission and the U. S. application No.12/044,354 submitted on March 7th, 2008 Described in, the complete disclosure of each of these files is incorporated herein by.

Except conventional flash chamber-they can include with around needle assemblies external environment condition connect ventilating mechanism-in addition to, Here it is also envisioned that arriving, needle assemblies can include the flash chamber with breather plug, and the breather plug is when blood flow is to flash chamber When seal, thus forbid in the chamber may accumulation any forced air move to the import of intubation in the opposite direction.Such as Shown in Figure 11-15B, here it is also envisioned that arriving, similar breather plug can be positioned in housing at such position, so as to ventilate Housing is divided into two chambers by plug, and the two chambers have the size and size of predetermined.And, porous vent for Blood keeps porous, and blow-by when with contacting blood.Hopefully, blood does not contact ventilation at initial streamer instruction Plug, but there is such sealing at component later point during use, as will be described in more detail here.

For example, as shown in figs. 11-14, a porous vent is positioned in housing at such position, so as to logical Housing is divided into two chambers by gas part, and the two chambers have the size and size of predetermined, so as to refer in initial streamer Blood does not contact porous vent during showing, but such contact occurring at point afterwards during use in component, such as here As will be described in more detail.

As shown in figs. 11-14, needle assemblies 410 include housing 412, and the housing 412 has fluid inlet end or first end 414 and fluid outlet or the second end 416.Needle assemblies 410 include limiting the outer wall 418 of enclosure interior.Outer wall 418 totally exists Longitudinal extending at first end 414, forms the elongated longitudinal Part I 419 with the first diameter.At the second end 416, outer wall 418 form Part II 421, and the Part II 421 has the overall Second bobbin diameter bigger than the first diameter of Part I 419. Correspondingly, housing 412 can form the structure with substantially T-shaped cross section.Outer wall 418 can be separated at the second end 416 Element 428, the separate element 428 for formed housing 412 main part 430 be attached, thereby assist in pin The manufacture and assembling of component 410.Part I 419 and Part II 421 relative to each other can with various arrangeds, as long as They can play a part of transport air between them, as discussed here.

Needle assemblies 410 also include fluid inlet intubation 436, first end 414 of the fluid inlet intubation 436 from housing 412 Extend.Fluid inlet intubation 436 includes outer end 439, and the outer end 439 limits sharp inclined-plane at patient's puncture end 438, and Extend in the first end 414 of housing 412, and can be fixedly mounted wherein.The feature of fluid inlet intubation 436 also exists In general cylindrical vestibule extends between each end, and connects with the inside of housing 412.

Needle assemblies 410 also include non-patient puncture end, and the non-patient puncture end is prolonged from the second end 414 of housing 412 Stretch.As shown in Figure 13, this can be by providing needle assemblies 410 the second intubation in the form of fluid outlet cannula 452 come real It is existing.Specifically, the end of fluid outlet cannula 452 can limit the sharp inclined-plane to form non-patient puncture end 462.Fluid Outlet cannula 452 extends in the second end 416 of housing 412, and can be fixedly mounted wherein.Fluid outlet cannula 452 are further characterized in that, general cylindrical vestibule is connected with the inside of housing 412.Fluid outlet cannula 452 is arranged on housing In 412, so as to inner 464 substantially coaxially by wherein, so as to fluid outlet cannula 452 substantially with import intubation 436 in End axially aligns.Hopefully, this at the position adjacent with the second end 416 of housing 412 by installing fluid outlet cannula 452 And realize, the phase of the inner 439 with import intubation 436 is extended in housing 412 so as to the inner 464 of fluid outlet cannula 452 Adjacent position.In addition, the inner 464 of fluid outlet cannula 452 is only spaced apart small distance with the inner 439 of import intubation 436, by This forms between them the axial gap for flowing into flash chamber 426 for blood hydrodynamic form outlet cannula 452.In fluid issuing The distance between the inner 464 of intubation 452 and the inner 439 of import intubation 436 form axial gap, it is sufficient to ensure blood quiet Arteries and veins is flow in flash chamber 426 after puncturing based on patient's blood pressure.In certain embodiments, between the axial direction less than 0.5mm Gap may cause inconsistent flash back（flushback）.

As seen in Figure 14 B, fluid inlet intubation 436 and fluid outlet cannula 452 are positioned in housing 412 Be sized, so as to realizing by the hope of component 410 flowing and realizing that effectively flash back is indicated.Specifically, the wall of housing 412 418 are sized to, there is provided the about 0.2mm of hydrodynamic form outlet cannula 452 is in the radial clearance at the region of its inside end 464. The blood flow of the substantially laminar-flow type in flash chamber 426 is realized in this gap, and prevents haemolysis.In addition, surrounding The little radial clearance that the region of inside end 464 is between the inner surface of wall 418 and fluid outlet cannula 452 enables droplet of blood Thinly launch across the radial clearance in flash chamber 426, referred to providing the flash back amplified with the blood of very small size Show.Thus, blood is just rapid on the first appearance in flash chamber 426 realizes that the flash back being readily seen that is indicated.Here it is contemplated to, goes out The inside end 464 of mouth intubation 452 can be partly supported in housing 412, as long as realizing entering flash chamber around inside end 464 Blood flow in 426.

May be selected in arrangement a kind of, there is provided single intubation.Such a arrangement is depicted in the embodiment of Figure 15 A-15B （Represent together with blood collection assembly, as will be described in more detail here）.In such a arrangement, fluid inlet is inserted Pipe and fluid outlet cannula are shown as a single intubation 470, and the intubation 470 has patient's puncture end 438, non-patient puncture end Hold 462 and extended their vestibule 442, and the body of intubation 470 is fixedly attached in a part for housing 412, and And completely by housing 412.The part for extending the intubation 470 of housing 412 is open including one or more, such as groove or hole 444, connected with providing between vestibule 442 and the flash chamber 436 in housing 412.The enforcement represented in Figure 15 A-15B Example in, two separate holes 444 are represented on the opposite side of intubation 470, while it is envisioned that arriving, it may include it is any amount of opening or Hole 444, with the blood flow for ensureing to enter in flash chamber 436.

Return Figure 11-14 embodiment, needle assemblies 410 also include be installed on the fluid outlet 416 of housing 412 can Sealing shroud 461.This can be by the second end 416 of housing 412（Such as on element 428）Mounting protrusion 429 arrange can Sealing shroud 461 and realize, the salable set 461 represents elastomer element, and the elastomer element can frictionally coordinate or be attached to In projection 429.When salable set 461 is under non-bias state, salable set 461 is covered in the outer of fluid outlet cannula 452 Non-patient puncture end 462 at end.However, the pressure that the salable response of set 461 is applied by the block of evacuated tube is by conquassation, with The outer end 460 of fluid outlet cannula 452 is just pushed through the block of salable set 461 and evacuated tube, as is known in the art As.

The embodiment of Figure 11-14 also includes porous vent 402, and the porous vent 402 is positioned at the interior of housing 412 Portion.Porous vent 402 is positioned in housing 412, housing 412 is divided into into two separate chambers, i.e., by flash chamber 426 first chambers for representing and the second chamber represented by secondary cavity 427.Porous vent 402 can be built by suitable material, As described above with respect to breather plug 900, although there is no the water wetted material expanded in contact.By this way, porous Ventilation part 402 is suitable to make its ventilation of air Jing, and represents loose structure, and the loose structure includes allowing blood Jing, and it passes through Multiple micropores.As used herein, as discussed in more detail, in needle assemblies 410 during use, the inside in porous vent 402 Micropore is at least partially filled with blood due to the negative pressure formed in secondary cavity 427.With the negative pressure phase in secondary cavity 427 Such filling micropore of combination prevents the air flow between secondary cavity 427 and flash chamber 426, and ensures that blood leads to The fluid resistance of porous vent 402 is crossed, as will be described in more detail.

Hopefully, porous vent 402 is positioned in the inside of housing 412, in Part I 419 and Part II 421 Between.By this way, the Part I 419 of housing 412 substantially limits flash chamber 426, and second of housing 412 421 are divided substantially to limit secondary cavity 427.Selectively, porous vent 402 can be positioned in the inside of housing 412, in horizontal stroke Across at the position of the transition between first diameter and the Second bobbin diameter of Part II 421 of Part I 419, such as in Figure 15 A As representing in the embodiment of 15B.In either case, porous vent 402 is the part of substantial cylindrical, the cylinder Shape part has wherein axially encirclement intubation（Particularly fluid outlet cannula 452）A part central opening.

The internal volume of housing 412 is by the volume of flash chamber 426 and secondary cavity 427 and by porous vent 402 The volume sum that micropore is represented is limited.Such internal volume is configured to, it is ensured that for certain attribute of needle assemblies 410, especially It is when emptying at least in part with regard to secondary cavity 427 when during use evacuated tube being applied to into needle assemblies 410 in needle assemblies 410 A wherein part for air is forming wherein the ability of negative pressure.How such secondary stress in secondary cavity 427 is based on blood When contact porous vent 402 and be partially filled with its micropore, by the micropore suction blood of porous vent 402.At this In a bright specific embodiment, the whole internal volume of housing 412 can be from about 300mm³To about 400mm³.Such a body Product is particularly useful for the expection of the needle assemblies 410 for conventional venipuncture is used, to be aspirated from patient using pin intubation Blood sample, the pin intubation has the conventional measuring device for venipuncture, as known in the art.With so A kind of internal volume, porous vent 402 is preferably positioned as in enclosure interior, so as to flash chamber 426 to be defined as have Represent the volume from about percent 5 to about percent 20 of whole whole volumes of housing 412, the preferably whole of housing 412 Overall volume from about percent 7 to about percent 12, the overall volume includes the volume of secondary cavity 427 and in porous vent The volume of the micropore in 402.The such a ratio of whole whole volumes of flash chamber 426 and housing 412, it is ensured that flash back chamber Room 426 has enough volumes suitably to make initial streamer visible, and preferably simultaneously anti-Hemostatic Oral Liquid is worn in initial vein Porous vent 402 is fully contacted during thorn, based on the initial accumulated of the pressure in secondary cavity 427 caused by vein pressure, The vein pressure forces blood to enter in flash chamber 426.Such volume ratio is effective for expected use, such as at this In describe in further detail as, wherein not contacting into the blood flow in flash chamber 426 in initial venipuncture Porous vent 402, and wherein at least a portion of air is based on the applying on vacuum blood collecting tube to needle assemblies 410, Extract out from secondary cavity 427.By this way, it is secondary when patient's puncture end 438 removes from patient and is externally exposed environment Chamber 427 can be effectively from flash chamber 426 and from fluid inlet intubation 436 to the suction blood of secondary cavity 427, so as to enter Enter and by porous vent 402.In a specific embodiment, the totality volume of housing 412 is about 380mm³, flash back Chamber 426 has about 30mm³Volume, secondary cavity 427 have about 300mm³Volume, and the micropore of porous vent 402 has About 50mm³Volume.

Needle assemblies 410 can be assembled as follows.Fluid inlet intubation 436 is determined through the first end 414 of housing 412 Position, is positioned in the interior section of housing 412 at Part I 419 so as to open wide inner 439, and patient's puncture end 438 extend to outside first end 414.Fluid outlet cannula 452 is positioned in housing 412 through opposite end, so as to open wide inner 464 It is positioned in the interior section of housing 412 at the adjacent Part I 419 in the inner 439 with fluid inlet intubation 436, at it Between have small gap, and non-patient puncture end is extended to outside the second end 416.Fluid inlet intubation 436 and stream Body outlet cannula 452 can be in any known manner, it is desirable to which ground is added wherein by medical grade adhesive.

In the optional embodiment for only including single intubation 470, such intubation 470 is attached in housing 412, so as to Opening 472 is positioned in the interior section of housing 412 at Part I 419, makes patient's puncture end 438 extend to first end Outside 414, and non-patient puncture end 462 is extended to outside the second end 416.

Porous vent 402 is then inserted in housing 412, and is positioned on fluid outlet cannula 452（Or it is single slotting On pipe 470）, and hereafter element 428 is attached on the second end 416, closes the inside of housing 412.Salable set 461 is then attached It is added in projection 429.Like this, the inside of housing 412 isolates with external environment condition, is used in the inside of housing 412 and outside The exclusive path of the fluid communication between environment is provided by patient's puncture end 438.

The needle assemblies 410 for assembling like this can be used together with blood collection base 403, the table such as in Figure 15 A-15B As describing in the embodiment shown.

In use, needle assemblies 410 can be provided with the collection base 403 being attached to thereon.Patient's puncture end 438 passes through The skin of patient is inserted and in the vascular system of patient, in preferably entering vein.In venipuncture, enclosed environment exists Realize in housing 412, because housing 412 is completely enclosed structure, and because salable set 461 closes the unique of housing 412 Outlet（That is, fluid outlet cannula 452）.The blood pressure of patient makes blood flow through patient's puncture end 438, incoming fluid import intubation In 436, and flow out inside end 439（Or by the opening 472 in the embodiment of Figure 15 A-15B）, flow into flash chamber 426, the flash chamber 426 is around the inner 464 of fluid outlet cannula 452.The transparent or semitransparent property of housing 412 is allowed Blood in flash chamber 426 can be seen, there is provided realize the instruction of venipuncture.

Because the inside of housing 412 is enclosed environment, so blood makes air arrest limit into the flowing of flash chamber 426 existing In enclosure interior, it is included in flash chamber 426, porous vent 402 and secondary cavity 427, and in fluid outlet cannula 452 It is interior, make so to arrest the air of limit wherein by slight pressurization.The size of flash chamber 426 and secondary cavity 427 and it is sized to So that its volume allows blood to be flowed in this initial venipuncture in flash chamber 426, but in porous vent 402 Porous vent 402 is completely attached to the anti-Hemostatic Oral Liquid of accumulation in the inner air pressure of secondary cavity 427, and or even be preferably prevented from blood Liquid partly contacts porous vent 402 in initial venipuncture.

After such initial venipuncture and streamer are visible, wherein the sample collection container with negative pressure, such as existing There is the vacuum blood collecting tube that technology is commonly known（It is not shown）, in being inserted in base 403.The block of such vacuum tank （It is not shown）Salable set 461 is contacted and moved, is made non-patient puncture end 462 pierce salable set 461 and was pierced vacuum appearance The block of device.At this moment, set up between non-patient puncture end 462 and the inside of evacuated collection containers and be in fluid communication.True Negative-pressure ward in empty collection vessel is gone forward side by side collected in the blood in flash chamber 426 in fluid outlet cannula 452 In entering evacuated collection containers.Together with the blood in flash chamber 426, the negative pressure in evacuated collection containers will also air At least a portion flash chamber 426 is extracted out by the micropore of porous vent 402 and secondary cavity 427 is extracted out, pump to and suction To in evacuated collection containers.In addition, the close proximity and alignment of fluid outlet cannula 452 and fluid inlet intubation 426 make blood Extract out from fluid inlet intubation 436 and from patient, while making such air extract out from flash chamber 426 and secondary cavity 427.

Such extraction of air reduces the pressure in flash chamber 426 and secondary cavity 427, with wherein relative to patient Blood stream and relative to external environment condition formed negative pressure.This has built up in the inside of housing 412 and is particularly dodging The negative pressure returned in chamber 426 and secondary cavity 427, sudden strain of a muscle is drawn into by other blood from fluid inlet intubation 436 and from patient In returning chamber 426, contacting blood porous vent 402 is made.Because blood fills flash chamber 426, blood is fully contacted and is dodging The surface of the porous vent 402 that chamber 426 extends is gone back to, and starts to fill the micropore of porous vent 402.Porous vent Such filling of 402 micropore-these micropores close porous directly in porous vent 402 and the interface of flash chamber 426 Ventilation part 402 avoids the air flow by it, but plays sealing by halves, because blood does not make porous vent 402 material expand or cut-out air flow, but the hole being instead only physically filled in porous vent 402.And, Because a part for the air in secondary cavity 427 is extracted out from secondary cavity 427, thus secondary cavity 427 represent it is wherein relative There is the closed chamber of negative pressure in external environment condition.Secondary cavity 427 therefore will continue in the micropore of porous vent 402 and Blood in flash chamber 426 has the suction effect by the micropore of porous vent 402 to secondary cavity 427, due to The micropore filling of the porous vent 402 of the interface of flash chamber 426 has blood without in the opposite direction from secondary cavity Any air of 427 releases, is thus effectively prevented air due to the micropore being filled and flows through porous vent 402.By in pair The suction that negative pressure in chamber 427 is formed, blood based on the micropore of filling porous vent 402 and based on by porous vent Zigzag path that 402 micropore is formed and there is fluid resistance, and therefore be the gradually suction with the fluid motion for weakening.

At this moment, evacuated collection containers and secondary cavity 427 are relative to external environment condition（With the blood stream relative to patient）All Under negative pressure, and therefore all play a part of from fluid inlet intubation 436 aspirate.This effect substantially can be set up in flash back Balance in chamber 426, do not pumped to by the micropore of porous vent 402 so as to the blood included in the flash chamber 426 or In suction secondary cavity 427 or in suction evacuated collection containers（By fluid inlet intubation 436）, but instead substantially dodging Return in chamber 426 and keep at steady state.Due to fluid outlet cannula 452 and fluid inlet intubation 436 close proximity and Alignment, and due to the balance set up in flash chamber 426（Based between evacuated collection containers and vacuum secondary cavity 427 Contrary suction force）, the negative pressure of evacuated collection containers directly extracts blood from patient by fluid inlet intubation 436.Blood enters Entering the continuous sucking of evacuated collection containers gradually increases the pressure in collection vessel.

Once evacuated collection containers are filled with the desired amount of blood, just container is removed from non-patient puncture end 462, by This releases the fluid communication between non-patient puncture end 462 and evacuated collection containers, and salable set 461 is then covered by and closes Close non-patient puncture end 462.Such suction due to lacking the negative pressure from vacuum collecting pipe, in secondary cavity 427 Negative pressure is realized for the slight suction of the blood in flash chamber 426 by the micropore of porous vent 402.However, due to By the zigzag path of the blood flow of the micropore of porous vent 402, such suction is slowly and gently.

By the way that the second evacuated collection containers are arranged in present 403, and by puncture block, in non-patient puncture end Formed between 462 and the inside of evacuated collection containers and be in fluid communication, hereafter evacuated collection containers in addition can be plugged into base 403 In and for by the sample collection of non-patient puncture end 462, as discussed above.In such further sampling When, evacuated collection containers and secondary cavity 427 all under negative pressure, and therefore all play a part of from fluid inlet intubation 436 to aspirate. As previously discussed, it is this to act on the balance substantially set up in flash chamber 426, thus prevent the bag in flash chamber 426 The blood for containing is drawn towards or is drawn in secondary cavity 427（By porous vent 402）.Due to fluid outlet cannula 452 and stream The close proximity and alignment of body import intubation 426, the negative pressure of evacuated collection containers directly extracts disease by fluid inlet intubation 436 The blood of people, as discussed above.Once any such evacuated collection containers in addition are filled with the desired amount of blood, just Container is removed from non-patient puncture end 462, is thus released between non-patient puncture end 462 and evacuated collection containers It is in fluid communication, salable set 461 is then covered by and closes non-patient puncture end 462.

Once the blood sample needed for all has been extracted by this way, just by patient's puncture end 438 from patient Vascular system remove, thus the opening of patient's puncture end 438 is externally exposed into environment.Due in enclosure interior and outside Exclusive communication path between environment is by patient's puncture end 438, so relative to external environment condition shape in secondary cavity 427 Into negative pressure can play the blood that will be included in the flash chamber 426 and in fluid inlet intubation 436 towards and through many The effect that hole ventilation part 402 is gradually aspirated.Such swabbing action is by any blood included in fluid inlet intubation 436 Patient's puncture end 438 is moved away from, thus prevents any blood from leaking out fluid inlet intubation 436 from patient's puncture end 438. Such negative pressure in secondary cavity 427 can continue in the prolongation time period in patient's puncture end 438 from after patient's removing With the gradually swabbing action for passing through porous vent 402, and it is slotting to be pumped in fluid inlet by porous vent 402 The whole of the residual blood included in pipe 436 and flash chamber 426, and/or be drawn in secondary cavity 427.Needle assemblies 410 Then can suitably be disposed in a known manner.Here it is contemplated to, the flash chamber 426 of reference picture 11-15B description can be adopted In any one of the embodiment of other place descriptions in this application.

In yet another embodiment, Figure 16-28 describes and may be selected to construct according to one kind of the needle assemblies 230 of the present invention.Such as As shown, needle assemblies 230 are analogously built with the needle assemblies 30 described above by reference to Fig. 1-10.Needle assemblies 230 include Optional releasing parts 208 can remove cannula guard 216 with selective.Needle assemblies 230 are generally comprised：Intubation 234, with housing 232 are associated；With safety shield 236, the during use and/or afterwards security mask intubation 234 in device is suitable to.As retouched in the past As stating, housing 232 can include that hub 264, specimen collection container receives port 276 and/or specimen collection container seat 278 and second sidewall 286, the second sidewall 286 at least partly surrounds the side wall 284 of specimen collection container seat 278.Hub 264 may be adapted to support inserting tubes 34 at least in part, and the intubation 34 includes patient end 240 and non-patient end 242, such as the previously described As.Intubation 34 can also include distally patient needle 252 and separate nearside non-patient pin 254, also as previously described that Sample.Needle assemblies 230 also include the flash chamber 298 for wherein limiting, as previously described.

As represented in Figure 16,18,20 and 21-25, needle assemblies 230 are represented in retracted position, make to remove Cannula guard 216 is associated and shields substantially intubation 234 with a part for housing 232.Cannula guard 216 and housing can be removed 232 part is pieceable, and is removable before the use of needle assemblies 230.Cannula guard 216 can be removed to carry For into before the use during sample collection, shielding intubation 234 specifically, shields the patient end 240 of intubation 234 Puncture end.In one embodiment, cannula guard 216 is configured to circumferentially around intubation 234.Cannula guard 216 has near End 246, the near-end 246 has interior section 248, and the interior section 248 is sized at least in part at one of housing 232 Point（Such as the outer surface 253 of hub 264）Upper extension.In another embodiment, cannula guard 216 can be removed with near-end 246, The near-end 246 has interior section 248, and the interior section 248 is sized at least in part in the outer surface 253 of hub 264 Upper extension, and extend at least a portion of the inside 258 of the distal end 260 of housing 232.

Cannula guard 216 can be removed can removably be paired to the one of hub 264 and/or specimen collection container seat 278 On part, such as by frictional engagement or fit mechanism.Selectively, can remove cannula guard 216 can be threadably engaged Pairing（It is not shown）, wherein screw thread（It is not shown）Can be arranged in hub 264 a part or specimen collection container seat 278, And/or can remove on cannula guard 216.In one embodiment, the near-end 246 of cannula guard 216 can be removed, it is slotting with removing The thickness of the remainder of pipe protective cover 216 is compared, the region 266 can with increase thickness, to provide for matching somebody with somebody with housing 232 To the Auxiliary support for engaging.In a further embodiment, the region 266 of thickness is increased, provided that, then provide and be used for and hub The Auxiliary support of 264 pairing engagements.

Cannula guard 216 can be removed can be had any suitably sized, and can be made up of any suitable material, to permit Perhaps the puncture end of the patient end 240 of intubation 234 before the use and/or transport during keep shielding.In one embodiment, Cannula guard 216 can be removed with enough intensity, to allow needle assemblies 230 to be packaged into " Hard Roll " packaging arrangement, such as routine As knowing, without for the damage of intubation 234 or needle assemblies 230.Exemplary removed cannula guard and exemplary Hard Roll packaging structure is for example disclosed in United States Patent (USP) No.6,997,913 and No.6, in 984,223, these patents each Complete disclosure is incorporated herein by.

Before the use, cannula guard 216 can be removed to remove from needle assemblies 230, such as by applying to disengage frictional engagement Or fit mechanism and/or back out the power being threadedly engaged.Once cannula guard 216 can be removed to remove from needle assemblies 230, cure Teacher can use needle assemblies 230, as described herein in the past.

And, as specifically represented in Figure 26-28, needle assemblies 230 can include releasing parts 208 may be selected, Such as may be selected to push button.In one embodiment, releasing parts 208 can start safety shield 236 and move from retracted position To extended position.In another embodiment, releasing parts 208 can start actuator, by safety shield 236 from retraction position Put and move to extended position.In the embodiment described in Figure 26-28, releasing parts 208 include part 210, and the part 210 has Constrained part 212 and passage area 214, as previously described.Constraint portions 212 can also limit interior notches 218, The interior notches 218 are at least partly limited by two suspension arms 220.Interior notches 218 are sized to accommodate housing through it 232 at least a portion, such as a part for hub 264.Figure 26-27 is the partial perspective view of needle assemblies 230, the needle assemblies 230 On sheath and intubation be removed, to show the mechanism of releasing parts 208.When releasing parts 208 are in first position, such as Shown in Figure 26, edge 222 may be provided in the part that it does not engage hub 264.When releasing parts 208 move to second When putting, as shown in Figure 27, two suspension arms 220 are all reduced, and edge 222 contacts a part for hub 264.

As shown in Figure 26, when releasing parts 208 are in first position, the retracted position with sheath（Represent in Figure 16 In）Corresponding, the edge 222 of interior notches 218 is separated with hub 264, and is suspended the constraint portions 224 of arm 220 and can be connect A part for tactile hub 264.Prevent safety shield from moving to extended position from constrained by constraint portions 212, such as class here As reference picture 3-4 is discussed more fully.As shown in Figure 27, when releasing parts 208 are deployed into the second place, with shield The extended position of set（Represent in fig. 17）Corresponding, edge 222 engages at least a portion of hub 264.Constraint portions 212 are got over Cross hub 264 to advance.Once constraint portions 212 have passed over hub 264 advancing, hub 264 just prevents releasing parts 208 from returning Reset condition returned before its actuating, such as by being engaged by locking with hub 264.Also as shown in Figure 17, needle assemblies 230 can be with Including multiple ribs 238, to prevent safety shield 236 relative to housing 232（Such as relative to specimen collection container seat 278）Rotate.

As Figure 24-25 shown, can remove cannula guard 216 can also include being adjoined with a part for releasing parts 208 Part, be thus physically prevented from the expansion of releasing parts 208, can remove cannula guard 216 until removing from needle assemblies 230. In one embodiment, cannula guard 216 can be removed including contact pin 274, the contact pin 274 is at least in part in releasing parts 208 Interior notches 218 in extend（Represent in Figure 28）, the first position for thus preventing releasing parts 208 from representing from such as Figure 16 Move to the second place as represented in Figure 17.Correspondingly, transport or standard in advance using front disposal during prevent safety shield 236 from retracted position accidental movement to extended position.

And, as shown in Figure 22-23, anti-interference flange 278 may be provided in it is adjacent with the distal end 260 of housing 232, such as It is adjacent with the distal end 282 of second sidewall 286, once to prevent safety shield 236 from moving to expanded position from retracted position, Safety shield 236 into housing 232 be forced to reenter.In one embodiment, flange 278 is attached at distal end 282 It is on the outer surface 284 of second sidewall 286 or integral with it, and be oriented and surmount the remote of housing 232 in a distal direction End 282 extends.As shown in Figure 23, when needle assemblies 230 are in extended position, flange 278 can shield blocking mechanism 292, The blocking mechanism 292 is similar in the past referring herein to the blocking mechanism of Fig. 9-10 descriptions.Blocking mechanism 292 is configured to, once peace Full sheath 236 moves to expanded position from retracted position, just prevents safety shield 236 from reentering in housing 232.So And, in some constructions, perhaps it is possible that by pry（It is not shown）It is inserted in a part for safety shield 236 and housing 232 Between, thus the adjacent part that needle assemblies 230 bend sufficient degree-blocking mechanism 292 can be disengaged, thus allow safety Sheath 236 is re-entered in housing 232.In order to prevent the insertion of such a pry, flange 278 can be provided, to shield The distal end 260 of housing 232 avoids by improper utilization.

Figure 29-38 describes an alternative embodiment of the invention, and wherein needle assemblies 330 are as described above by similarly Build, be a difference in that the construction of housing 332.Needle assemblies 330 are generally comprised：Intubation 334, is associated with housing 332；And safety Sheath 336, is suitable to carry out security mask to intubation 334 during use and/or afterwards in device.Needle assemblies 330 also include hub Disk 364 and flash chamber 398, the hub 364 is used at least a portion of support inserting tubes 334, as previously described.

In the embodiment represented in Figure 29-38, housing 332 can include Part I 344, and Part II 346 connects To on Part I 344.Part I 344 can be along the mobile axis T of safety shield 336（Represent in Figure 32）For second Part 346 is in distally.In one embodiment, Part I 344 and Part II 346 are collectively forming.In another embodiment In, Part I 344 and Part II 346 are separately formed and and then assembling.In yet another embodiment, Part I 344 and Part II 346 can be fixed together by bayonet mode.Selectively, Part I 344 and Part II 346 can To be bonded together by using traditional binders.

As shown in Figure 33-34, intubation 334 may be positioned such that part in the inside 350 of Part II 346, and portion Divide in the inside 352 of Part I 344.In another embodiment, the non-patient end 342 of intubation 334 can be positioned at In the inside 350 of two parts 346, and the puncture end of at least patient end 340 of intubation 334 surmounts Part I 344 and extends. Hub 364 can be positioned in the inside 352 of Part I 344, although in some embodiments, it may be desirable to, by hub Disk 364 is positioned to part in the inside 350 of Part II 346, and part is in the inside 352 of Part I 344.Another In one embodiment, Part II 346 can include conventional examples collection vessel seat 378.In yet another embodiment, with sample Collection vessel（Represent in Figure 123）Pieceable specimen collection container receives port 380 to be limited in Part II 346.

When safety shield 336 is in retracted position, flash chamber 398 for doctor be it is visible, as shown in Figure 29. Figure 29-34 are referred again to, housing 332, such as Part I 344 can include side wall 358, and the side wall 358 is therein with being limited to Watch window 360, the window is represented in Figure 29-32.In one embodiment, watch window 360 includes complete by side wall 358 The opening of encirclement.In another embodiment, watch window 360 includes the cut-out of housing 332.In another embodiment In, watch window 360 is included in the transparent and/or trnaslucent materials in opening.In yet another embodiment, watch window 360 Including being at least partly unlimited cut-out, i.e. watch window 360 is not surrounded completely by the side wall 358 of housing 332.

According to one embodiment of the present of invention, when sheath 336 is in retracted position, at least one of flash chamber 398 It is visible to divide by watch window 360.In another embodiment, at least a portion limit of the Part I 344 of housing 332 Determine watch window 360, and when sheath is in retracted position, the Part I 344 that flash chamber 398 passes through housing 332 Watch window 360 is visible.In another embodiment, safety shield 336 can be by translucent and/or transparent material shape Into so as to flash chamber 398 is all visible by a part for watch window 360 and safety shield 336.In another enforcement In example, the Part I 344 of safety shield 336 and housing 332 is all made up of transparent material or trnaslucent materials, so as to streamer chamber Room 398 is all visible by two kinds of structures.Part I 344 and safety shield 336 can by it is identical or different translucent and/ Or transparent material is made.In another embodiment, the patient end 340 of intubation 334 can include inclined-plane 338, and in housing The position of the watch window 360 in 332 and the orientation on inclined-plane 338, the i.e. orientation of the inclined surface on inclined-plane 338, it is corresponding.This can To help doctor to be properly oriented to intubation 334 in patient body, and without observing the patient end 340 of intubation 334.

As shown in Figure 33, safety shield 336 can all be arranged in the Part I of housing 332 in retracted position In 344.In one embodiment, safety shield 336 is suitable at least partly surround（Such as circumferentially around）Intubation 334 is at least A part.In one embodiment, safety shield 336 can be made up of substantially rigid material.In another embodiment, safety Sheath 336 can be made up of any basic elastic deformable material, and the material has elasticity, it is sufficient to make the safety shield 336 can be with Compressed and expanded without its substantial damage, so as to it can be configured to, folded against itself in pleated sheets arrangement.

As shown in Figure 33-34, spring 368 can be in a part for safety shield 336 and the Part I of housing 332 Bias between 344 part.In one embodiment, portions of proximal 372 and Part I 344 of the spring 368 in sheath 336 Inside 352 inner surface 384 between bias.In another embodiment, spring 368 sheath 336 portions of proximal 372 with Bias between the distal end 376 of Part II 346.In yet another embodiment, biased sections of the spring 368 in safety shield 336 388 and Part I 344 inside 352 inner surface 384 and Part II 346 distal end 376 any one between bias.

As shown in Figure 29-38, safety shield 336 can be moved by spring 368 from the retracted position represented in Figure 29 Move the extended position for representing in fig. 30.During safety shield 336 moves to extended position from retracted position, spring 368 So that safety shield 336 proceeds to the distal portion away from Part I 344 from the position in the Part I 344 of housing 332 Divide 392 position.In this embodiment, safety shield 336 is suitable to be moved between retracted position and extended position, in the contracting During return is put, the puncture end of the patient end 340 of intubation 334 is at least exposed to be close to patient, in the extended position, disease The puncture end at people end 340 is encapsulated in other words by security mask in order to avoid exposure.Patient's blood vessel is going in intubation 334 （It is not shown）Inside while, or intubation 334 from patient removing after, safety shield 336 can be at least part of Launch in intubation 334 on ground.If while intubation 334 is going into the inside of patient's blood vessel, safety shield 336 occur from Retracted position to extended position movement, then the distal portions 394 of safety shield 336 will contact patient skin.

In yet another embodiment, needle assemblies 330 can also include blocking mechanism 396, similar to the previously described stop Mechanism, to move to extended position from retracted position once safety shield 336 once prevent safety shield 336 from reentering Housing 332.Selectively, as shown in Figure 33-34, limiter 390 and fracture 386 are represented in positioned opposite, so as to fracture 386 are included in housing 332, and specifically in the distal end 392 of Part I 344, and limiter 390 is included in safety protective It is adjacent with the portions of proximal 372 of sheath 336 in set 336.

As shown in Figure 29-36, releasing parts 308 such as push button, can start safety shield 336 from retracted position Move to extended position.In another embodiment, releasing parts 308 can start actuator, by safety shield 336 from contracting Return is put and moves to extended position.In Figure 29-34 describe embodiment in, releasing parts 308 can by with it is the previously described Releasing parts substantially similar manner is operated, however, passage area 310 can limit at least one substantial circular opening.As schemed Shown in 36, the constraint portions 312 of releasing parts 308 can also limit part circular opening.Figure 35 represents cuing open for needle assemblies 330 View, wherein releasing parts 308 are corresponding with the sheath 336 in retracted position in first position.As shown in Figure 35, Constraint portions 312 are engaged with least a portion of safety shield 336, so as to the shoulder 314 of releasing parts 308 prevents safety protective Set 336 moves to extended position by the bias of spring 368.In such configuration, constraint portions 312 and passage area 310 are limited Surely there is the continuous part circular opening of different-diameter.In one embodiment, passage area 310 has diameter D1, and There is constraint portions 312 diameter D2, wherein D2 to be less than D1.When releasing parts 308 are in first position, safety shield 336 to Partially it is aligned with the diameter of the opening of constraint portions 312 and by its constraint, thus safety shield 336 is maintained at into retraction In position.When releasing parts 308 move to the second place, constraint portions 312 proceed to safety shield 336 and passage area Below 310, the opening for making increase diameter is aligned with safety shield 336, thus allows safety shield 336 to pass through and move It is dynamic.

In one embodiment, constraint portions 312 can be sized to, circumferentially around a part for housing 332, such as hub Disk 364.Optionally, releasing parts 308 can include invariant feature, and the invariant feature is used for stablizing releasing parts 308 In first position, and the corresponding shoulder 318 of housing 332 is engaged, as shown in Figure 29 and 35.In one embodiment, it is stable Feature can include detent projection 316, such as two detent projections 316, for engaging the corresponding shoulder 318 of housing 332 and inciting somebody to action Releasing parts 308 are stable in first position.When quilt on the direction that arrow R of the releasing parts 308 in by Figure 29 and 36 is represented During pressing, safety shield 336 is moved to extended position, represents in fig. 30.When releasing parts 308 are being represented by arrow R Side is when advancing up, and detent projection 316 is received within the recess 320 in housing 332 along in downward direction advancing（Table Show in Figure 35）.Due to compared with the diameter of constraint portions 312, the increase diameter of passage area 310 and in recess 320 The presence of detent projection 316, safety shield 336 advances through passage area 310, thus by safety shield 336 from retracted position Move to extended position.

And, as shown in Figure 37-38, needle assemblies 330 can include a kind of removable cannula guard 324, and this can be removed Cannula guard 324 is removed for surrounding intubation 334, specifically the puncture end of patient end 340 before the use.As herein before As description, can remove cannula guard 324 can include tab portion 326, and the tab portion 326 is configured to prevent release portion Part 308 moves to the second place from first position.In this embodiment, tab portion 326 includes upper surface 354, the upper table Face 354 is configured to the lower surface 356 in the face of releasing parts 308, to provide between them adjacent or interfere.Once doctor is from pin Component 330 removes can remove cannula guard 324, and releasing parts 308 just can launch, as described herein.

As shown in Figure 37-38, can remove cannula guard 324 can include conical section 328, and the conical section 328 has Have for allowing doctor to be easier to catch that cannula guard 324 can be removed so as to the profile removed from needle assemblies 330.In another reality In applying example, can remove cannula guard 324 can have reinforced pipe 348, and the reinforced pipe 348 is arranged in and can remove cannula guard 324 Inside in, and be configured at least partly surround intubation 334.Reinforced pipe 348 can also include fastener 362, and this is tight It is fixedly mounted with and puts 362 and be fixed on the hub 364 of needle assemblies 330 for cannula guard 324 removably will can be removed.In an enforcement In example, fastener 362 may include corresponding frictional fit or press-fitting structure.In another embodiment, fastener 362 Corresponding helicitic texture is may include, the correspondence helicitic texture is used to match engagement, it is allowed to which doctor is by removing cannula guard 324 Rotational motion relative to housing 332 is removed from needle assemblies 330 and can remove cannula guard 324.

Figure 39-58 shows another embodiment of the needle assemblies 530 of the present invention.Figure 39,41,43,45 and 47 each show With the needle assemblies 530 that can remove cannula guard 512, it is necessary before the use of needle assemblies 530 that this can remove cannula guard 512 Remove, as previously described.Cannula guard 512 can be removed can include tab portion 512a, the tab portion 512a structure Cause to prevent releasing parts 508 to be pressed.In this embodiment, tab portion 512a is designed to, there is provided in releasing parts 508 Adjacent or interference between safety shield 536, as previously described.

Needle assemblies 530 are generally comprised：Intubation 534, is associated with a part for housing 532, as support inserting tubes 534 At least one of hub 564；And/or specimen collection container seat 578.Needle assemblies also generally comprise safety shield 536, the safety Sheath 536 is suitable to the during use and/or afterwards security mask intubation 534 in needle assemblies 530.Needle assemblies 530 are additionally included in shell Flash chamber 598 at least a portion of body 532, as previously described.

In one embodiment, needle assemblies 530 include Part I 538, and Part II 540 is connected to Part I 538 On.Part II 540 limits internal 542, and the inside 542 is configured to receive specimen collection container wherein, and such as vacuumized blood is received Collector（It is not shown）.In one embodiment, Part II 540 is specimen collection container seat 578.In another embodiment, Part II 540 is blood collection container seat 578, and needle assemblies 530 are blood collection assemblies 530.

In one embodiment, Part II 540 includes proximal curved ends 544.Specifically as shown in Figure 41-42, arc Each limits generally concave proximal region 546 for the side part of near-end 544, and specifically as shown in Figure 43-44, arc is near Each limits the proximal region 548 of substantially convex for the top at end 544 and base section, this substantially convex proximal region 548 by The generally concave proximal region 546 of side part separates.Optionally, the outer surface 550 of Part II 540 can include relatively Oncus region 552, these relative oncus regions 552 are used for allowing doctor to easily hold on Part II 540.In one embodiment In, can be made up of viscous elastomeric material with respect to oncus region 552.

The distal end 554 of Part II 540 can also include engaging mechanism 556, and the engaging mechanism 556 is used for engaging first Divide 538.In one embodiment, the distal end 554 of Part II 540 includes at least one recess 558, represents in Figure 47-48, The recess 558 is used for being engaged with the pairing of projection 560, and the projection 560 is integral with the near-end 562 of Part I 538.Part I 538 and Part II 540 can be fixed together by press-fit locking mechanism, screwed mechanism, bayonet mechanism, Huo Zheke To be bonded together by using traditional binders.Optionally, the outer surface 566 of Part I 538 can also include phase To oncus region 568, these relative oncus regions 568 are used for allowing doctor to easily hold on Part I 538.Intubation 534 can To be positioned to, partly in the inside 42 of Part II 540, and part is in the inside 570 of Part I 538, such as in the past As description.

Optionally, the Part II 540 of the present embodiment may include that at least one pipe is pre-loaded into indicator 572, and the pipe is pre- Load indicator 572 is used for indicating specimen collection container to doctor（Such as empty blood tube）The appropriate depth that can be plugged into, and not With the inside for entering emptying blood tube, such as penetrating by intubation 534.Optionally, a part of of intubation 534 can be by can pierce Thoroughly set 582 is protected, and this can pierce proximal end arrangement of the set 582 around intubation 534.In one embodiment, being pre-loaded into indicator 572 can To be to rise or recessed band, the rise or recessed band are arranged in the inside of Part II 540 or outer surface, such as in Part II In the inside of 540 side wall or outer surface.Selectively, be pre-loaded into indicator 572 can be in the inside of Part II 540 or Coloring or texture band in outside.In another embodiment, it can be continuous or segmentation band to be pre-loaded into indicator 572.With this The mode of kind, before the use, vacuum blood collecting tube " can be pre-loaded into " in needle assemblies 530.

In one embodiment, support inserting tubes 534 at least in part of hub 564, as previously described.Including rear portion The hub 564 of hub portion 574 and forward hub portion 576 is preferably by transparent or semitransparent polymeric material or resin mold Pressure.Like this, hub 564, and specifically forward hub portion 576, limit flash chamber 598.In one embodiment, A part of engagement front hub portion 576 of the Part II 540 that rear hub portion 574 passes through housing 532, to form sealing Flash chamber 598.In such configuration, flash chamber 598 can pass through the interior of the Jing Part II 540 of rear hub portion 574 The introducing in portion 542 and formed, for in the inside 570 of Part I 538 arrange forward hub portion 576 a part Engage.Housing 532 can include forward hub portion 576 and rear hub portion 574, the rear hub portion 574 with it is front Portion's hub portion 576 can connect, and limit flash chamber between them.In one embodiment, rear hub portion 574 Projection 580 extended the Part II 540 of housing 532, and the correspondence being matingly bonded in forward hub portion 576 is recessed Mouthful.Correspondingly, in a kind of construction, rear hub portion 574 can pass through at least a portion of specimen collection container seat 578 with it is front Portion's hub portion 576 connects, and represents in Figure 39.In another kind of construction, rear hub portion 576 limits wherein sample receipts Collection container receipt port 504, represents in Figure 55.

As shown in Figure 49, in one embodiment, at least a portion of rear hub portion 574 is constrained on second Divide in 540 inside 542, a part of so as to flash chamber 598 can be formed in Part II 540, such as in blood collection In base.In another embodiment, flash chamber 598 is formed as, at least in part in forward hub portion 576, and And at least in part in rear hub portion 574.In such configuration, the elongate profile of needle assemblies 530 can be kept, while increasing It is big when safety shield 536 is in retracted position for the visible flash chamber 598 of doctor inside volume.

As shown in Figure 49, in one embodiment, the shape between forward hub portion 538 and rear hub portion 540 Into space 598a can allow the compression of wherein air, enough pressure is thus produced, to force fluid（Such as blood）Into Intubation 534 and be forced in flash chamber 598.In one embodiment, space 598a is sized to, and accommodates enough volumes Compressed air, is entered in flash chamber 598 with forcing blood to enter intubation 534.

As previously described, it is possible to achieve safety shield is from the retracted position represented in Figure 39 to the table in Figure 40 The movement of the extended position for showing, makes that cannula guard 512 can be removed in place in Figure 39.In one embodiment, in safety shield The spring 584 arranged between 536 part and a part for housing 532 is to extended position bias safe sheath 536.Another In individual embodiment, releasing parts 508 such as push button, can activate safety shield 536 and move to extension bit from retracted position Put, as previously described.Selectively, releasing parts 508 can start actuator, by safety shield 536 from retraction position Put and move to extended position, also as previously described.

During safety shield 536 moves to extended position from retracted position, spring 584 makes safety shield 536 from least Partly the position in the Part I 538 of housing 532 proceeds to the position of the distal region 586 away from Part I 538, As shown in Figure 43-44.In this embodiment, safety shield 536 is suitable to be moved between retracted position and extended position, In the retracted position, in order to be close to the puncture end that patient at least exposes the patient end 588 of intubation 534, in the extended position, The puncture end of the patient end 588 of intubation 534 is encapsulated in other words by security mask in order to avoid exposure.Note, although Figure 39, 41st, the removed cannula guard 512 that 43,46 and 47 each expression are arranged in retracted position in intubation 534, but in pin group Removing before the use of part 530 can remove cannula guard 512, expose intubation 534.

As shown in Figure 44, in extended position, by the proximal edges of safety shield 536 along 590 against Part I 538 Distally limiter 592 engagement, safety shield 536 is maintained in the distal region 586 of Part I 538.As in Figure 48 It is shown, also in extended position, by the proximal edges of safety shield 536 along 590 and the stop of the Part I 538 of housing 532 The engagement of mechanism 594, prevents safety shield 536 from crossing the engagement at distal region 586, reenters the first of housing 532 Part 538.

As shown in Figure 48, blocking mechanism 594 can include locking tab 596, and the locking tab 596 is in safety shield 536 is deflection when moving to extended position from retracted position, once but safety shield 536 in extended position, it is just basic Can not bend.Locking tab 596 can include conical surface 528, and the conical surface 528 is allowed due to moving from retracted position Make safety shield 536 cross it to the applying power of spring 584 during extended position to advance.Locking tab 596 can also include Stop surfaces 526, to move to extended position once having occurred and that from retracted position, just prevent safety shield 536 from crossing lock Static joining-pin 596.Therefore, once safety shield 536 moves to extended position, the safety protective of needle assemblies 530 from retracted position Set 536 is just remained locked in position in intubation 534.

As shown in Figure 51-52, locking tab 596a may be selected can be included in needle assemblies 530.Locking tab 596a Including with similar geometry described above, it is allowed to the safety when sheath 536 moves to extended position from retracted position Sheath 536 crosses the locking tab 596a movement by flexure, and basic once sheath 536 is moved into extended position Prevent axial deflection.As shown in Figure 52, a part of of housing 532 can arrange around locking tab 596a, to be essentially prevented from Flexure in the radial direction in Figure 52 by shown in arrow B.

As shown in Figure 53-55, during the assembling of the present embodiment, intubation 534 can with forward hub portion 576 and after Portion's hub portion 574 is engaged, to form hub 564, the hub 564 wherein have flash chamber 598, make intubation 534 with The internal fluid communication of flash chamber 598.Spring 584 can be arranged in of forward hub portion 576 and safety shield 536 /.Safety shield 536 can be inserted in the inside of the second housing parts 532a by a part for releasing parts 508 It is interior.As shown in Figure 53, a part of of housing 536 can include engaging mechanism 522, and the engaging mechanism 522 is used for being bonded on hub Corresponding contact pin 524 on disk 564, so that hub 564 is engaged with the second housing parts 532a.It is shown that locking Contact pin 596a can be provided in the distal end of the second housing parts 532a.When the housing parts 532a of hub 564 and second is engaged, Sheath 536 is biased from spring 584 to extended position.However, shoulder 514 He of the releasing parts 508 by engagement safety shield 536 Bias of the restricted spring of constraint portions 520 of releasing parts 508 in first position.As shown in Figure 53-55, releasing parts 508 assembling can be completed on nearside or backward directions, however, here it is also envisioned that arrive, assembling can be orientated from upward direction, As shown in Figure 65-66, or distally or forward direction orientation.

As shown in Figure 56, hub 564 can be by the way that forward hub portion 576 be engaged with rear hub portion 574 And formed.Intubation 534 can be engaged and part with least one of forward hub portion 576 and rear hub portion 574 Be supported by it.Porous plug 510 can be arranged between forward hub portion 576 and rear hub portion 574, between them In the flash chamber 598 of restriction, and it is in fluid communication with intubation 534.

As shown in Figure 57-58, needle assemblies 530 can include non-patient pin 516（Or the non-patient end of intubation）, the non-disease People's pin 516 has the pierced set 582 being disposed thereon, and can be aligned with patient needle 518 through flash chamber 598, should Flash chamber 598 is limited in hub 564.Spring 584 can be arranged in the one of forward hub portion 576 and safety shield 536 Between part.Safety shield 536 is inserted into the inside of the second housing parts 532a by a part for releasing parts 508 It is interior.The safety shield 536 of combination, the second housing parts 532a, hub 564 and intubation 534 are inserted into the 3rd housing parts In 532b, such as in specimen collection container seat or blood collection base.

Here it is contemplated that hub 564, intubation 534, the housing parts 532a of safety shield 536 and second can be carried integrally For in the 3rd housing parts 532b, as in blood collection base.Selectively, hub 564, intubation 534, safety shield 536, And second housing parts 532a may be provided in non-integral arrangement, wherein hub 564 can include specimen collection container receive end Mouth 504, represents in Figure 55, the specimen collection container receives port 504 to be suitable to subsequently engage with specimen collection container.

As shown in Figure 59-63, non-integral needle assemblies 630 are analogously constructed with embodiments described above.At one In embodiment, forward hub portion 674 and rear hub portion 676 are engaged, the weldering of the excircle 678 of the adjacent hubs 664 of such as Jing Connect and for good and all engage.Flash chamber 698 can be formed between forward hub portion 674 and rear hub portion 676.Another In individual embodiment, forward hub portion 674 and rear hub portion 676 at least one by transparent or semitransparent polymeric material Or resin is formed, such as it is molded.Correspondingly, flash chamber 698 by hub 664 for doctor is visible.

First housing parts 632a can be arranged around at least a portion of forward hub portion 674, and safety shield 636 Can arrange around the patient end 640 of intubation 634 with cannula guard 612 can be removed, and engage with the first housing parts 632a, As previously described.Before the use, distal cannula shield 646 may be provided in and at least partly surround intubation 634 Non-patient end 642.Distal cannula shield 646 can engage at least a portion of the first housing parts 632a, and apply allusion quotation Can be from its removing during type artificial pressure.Distal cannula shield 646 and cannula guard 612 can be removed all it is provided, with medical treatment The non-patient end 642 of intubation 634 is made before the startup of process（Or non-patient pin）With the patient end 640 of intubation 634（Or patient Pin）Avoid and doctor's brought into incidental contact.

Rear hub portion 676 also includes that specimen collection container engages port 656, represents in Figure 61 and 63, the sample Collection vessel engages port 656 and specimen collection container seat 652（As shown in Figure 64）, it is engageable such as blood collection base 's.In another embodiment, specimen collection container engagement port 656 and specimen collection container, such as vacuum blood collecting tube, be It is directly pieceable.Here the sudden strain of a muscle configured similarly to that it is further contemplated that arriving, with the mark 598 referring to the drawings represented in Figure 49 Stream chamber, can adopt in the design.

As shown in Figure 65-66, the auxiliary body 668 of needle assemblies 630 is represented.In this embodiment, releasing parts 608 It is suitable to move to the second place from first position, as previously described.Releasing parts 608 also include projection 610, work as release When part moves to the second place from first position, the projection 610 deforms at least a portion of housing 632, such as makes and release The adjacent tab portion 638 of part 608 deforms.Releasing parts 608 are constrained in by the deformation of the tab portion 638 of housing 632 In two positions, thus prevent releasing parts 608 from returning to first position.

Figure 67-72 describes an alternative embodiment of the invention, wherein collection assembly 730 and above-described embodiment analogously structure Make, be a difference in that the construction and safety shield 736 of safety shield 736 for the mode of connection of housing 732.Needle assemblies 730 1 As include intubation 734, the intubation 734 is associated with housing 732, such as supported by hub 764, as previously described.Streamer Chamber 798 is associated with a part for housing 732, is such as limited in hub 764.

In the embodiment represented in Figure 67-72, safety shield 736 can include：Part I 710, such as arm section；With Part II 712, such as jacket portions, Part II 712 is connected on Part I 710.Part I 710 is configured to, and works as doctor When Normal University's body is applied to typical ARTIFICIAL FORCE on safety shield 736 on the direction represented by arrow C, along the longitudinal direction of intubation 734 Axis L is sliding engaged a part for housing 732, and the longitudinal axes L is represented in Figure 71.In one embodiment, first Divide 710 to be configured to, be sliding engaged coasting mechanism 714, such as slide along, the coasting mechanism 714 is integral with housing 732. In another embodiment, a part for housing 732 and a part for safety shield 736 limit engagement coasting mechanism 714, wherein pacifying A part for full sheath 736 is axially movable relative to a part for housing 732.

In one embodiment, Part I 710 includes projection 718, and the projection 718 is used for being sliding engaged groove 720, The groove 720 is recessed in a part for outer surface 716 for housing 732, thus sets up coasting mechanism 714.In another enforcement In example, Part I 710 includes the recess for being sliding engaged a projection, outer surface 716 of the projection in housing 732 Top extends.Part I 710 can include gripping region 722, and the gripping region 722 is used for receiving the finger of doctor, to help Safety shield 736 is helped to proceed to the extension bit represented in Figure 68 from the retracted position represented in Figure 67 along coasting mechanism 714 Put.

When sheath 736 is in retracted position, the Part II 712 of safety shield 736 is suitable at least partly surround（Such as Circumferentially around）A part for the hub 764 being at least partially disposed in housing 732, is retracting so as to work as safety shield 736 When in position, wherein the flash chamber 798 for limiting is at least partly visible for doctor.In one embodiment, streamer chamber At least a portion of room 798 is by the watch window 724 or cut-out in the Part II 712 of safety shield 736 can See.In another embodiment, the Part II 712 of safety shield 736 can be built by transparent material and/or trnaslucent materials Make, so as to flash chamber 798 is visible through it.

In this embodiment, safety shield 736 is suitable to the retracted position shown in Figure 67 and shown in Figure 68 Move between extended position, in the retracted position, in order to be close to the puncture that patient at least exposes the patient end 740 of intubation 734 End, in the extended position, the encapsulated security mask in other words in puncture end of intubation 734 is in order to avoid exposure.Safety shield 736 Part II 712 is suitable at least partly surround（Such as circumferentially around）At least one of intubation 734 in extended position Point.In another embodiment, the patient end 740 of intubation 734 in extended position by safety shield Part II 712 at least Partially around.

Patient's blood vessel is going in intubation 734（It is not shown）Inside while, or in intubation 734 from patient After removing, safety shield 736 can launch in intubation 734.If being going into the inside of patient's blood vessel in intubation 734 Meanwhile, safety shield 736 moves to extended position from retracted position to be occurred, then safety shield 736（Such as safety shield 736 Part II 712）Distal portions 744 will contact the skin of patient.In one embodiment, safety shield 736 includes：Ratchet Mechanism, provisionally constrains in safety shield 736 in retracted position；With locking mechanism 750, it is suitable to be moved in safety shield 736 Safety shield 736 is maintained in extended position to after extended position.As shown in Figure 71, first of safety shield 736 Divide 710 can include locking mechanism 750, when safety shield 736 is in retracted position, the locking mechanism 750 bends or no Then against a part of radially biased of housing 732, such as by a part for Part I 710.As shown in Figure 72, once safety Sheath 736 moves to extended position, and locking mechanism 750 just advances, and for example the longitudinal axes L along intubation 734 is longitudinally advanced, until The contact with housing 732 is interrupted.At this moment, locking mechanism 750 is maintained in the general parallel orientation orientation relative to intubation 734 Radially biased power is released, and locking mechanism swings to intubation 734, as represented by arrowd, to engage housing 732 Distal end.Once locking mechanism 750 is engaged with the distal end of housing 732, safety shield 736 is just prevented to be retracted into from extended position Retracted position.

Optional needle assemblies 830 are expressed, and reference picture 73-86 is described, and the optional needle assemblies 830 have can be slided Dynamic safety shield 836.In such configuration, needle assemblies 830 are generally comprised：Intubation 834, is associated with a part for housing 832； With safety shield 836, it is suitable to carry out security mask to intubation 834 during use and/or afterwards in device.Housing 832 it is interior The portions of proximal 838 in portion can be configured to receive vacuum blood collecting tube wherein（It is not shown）, and interior ridge can be included 840, as shown in figure 76, the interior ridge 840 is used for limiting the portions of proximal 838 that vacuum blood collecting tube passes through housing 832 Advance.

Intubation 834 can include distally patient needle 44（Or the patient end of single intubation）With nearside non-patient pin 46（Or it is single The non-patient end of individual intubation）.Nearside non-patient pin 46 can be for vacuum blood collecting tube（It is not shown）Puncture be used.Distally disease People's pin 44 can make inclined-plane, be used for piercing through patient skin and the puncture end into patient's vascular to limit.Intubation 834 By at least a portion of housing 832（Such as hub portion 864）Support.Flash chamber 898 can be limited in hub 864, such as with As front description.In one embodiment, hub 864 and intubation 834 can be integrally formed with the remainder of housing 832. Selectively, hub 864 and/or intubation 834 can be separately formed, and be subsequently assembled.

In the embodiment represented in Figure 73-86, safety shield 836 can include：Part I 810, such as arm section；With Part II 812, such as jacket portions.Part I 810 and Part II 812 are connected.Part I 810 can include catching Part 814, this catches part 814 for receiving the finger of doctor, to help safety shield 836 from retracted position to extended position Advance, in the retracted position expose patient end 44, represent in Figure 75-79, in the extended position, shield patient end 44, represent in Figure 82-86.

Safety shield 836 is configured to, and along coasting mechanism 816 part for hub 864 is sliding engaged, the coasting mechanism 816 upper surfaces 820 and the lower surface 818 of safety shield 836 by hub 864, the such as Part II 812 of safety shield 836 Lower surface, interface set up.The interface of upper surface 820 and lower surface 818 could be arranged to Frictional Slipping between two surfaces. Selectively, upper surface 820 can be conformed with（It is not shown）, as previously described, the projection is used to be received in correspondence Groove（It is not shown）It is interior, as previously discussed, in a part for lower surface 818.Selectively, upper surface 820 can be with It is provided with for receiving projection（It is not shown）Groove（It is not shown）, part extension of the projection from lower surface 818.

In one embodiment, the Part I 810 of sheath 836 can be along the longitudinal axis T of intubation 834（Represent in figure In 75）It is sliding engaged a part for hub 864.As shown in Figure 77, the Part I 810 of sheath 836 can have first End 850, the first end 850 is sliding engaged a part for hub 864, so as to the lower surface 818 of sheath 836 is sliding engaged hub The upper surface 820 of disk 864.The Part I 810 of sheath 836 can have the second end 852, represent that this second in Figure 77-78 End 852 extended at least in part a part for housing 832.In another embodiment, the second end 852 of Part I 810 A part for the outer surface 856 of housing 832 can at least in part be extended.In yet another embodiment, as shown in Figure 75, Second end 852 of Part I 810 extended at least in part groove 858, and the groove 858 is limited to the outer surface of housing 832 In 856.Groove 858 can be in housing 832 substantially along the longitudinal axis T extensions of intubation 834.When sheath 836 is from retracted position When moving to extended position, the Part I 810 of sheath 836 can slide in groove 858.In another embodiment, such as Shown in Figure 74, Part I 810 can have contour surface 868, and the contour surface 868 is substantially taken turns with the distally of housing 832 Wide surface 870 is corresponding.

The Part II 812 of safety shield 836 is suitable at least partly surround（Such as circumferentially around）In retracted position Hub 864 at least a portion on.In one embodiment, Part II 812 around intubation 834 a part arrangement, and Axially align with a part for Part I 810, to move to extended position from retracted position around intubation 834.

Before by the startup of doctor, by a part for sheath 836 and housing 832 and/or a part for hub 864 Resistance engagement, it is also possible to prevent safety shield 836 from advancing from housing 832 is unexpected.When being represented by the arrow R in Figure 77 When exerting a force to catch on part 814 by doctor on direction, safety shield 836 is in a distal direction along the expression in Figure 75 Longitudinal axis T advances from housing 832.

With reference to Figure 79 and 86, safety shield 836 can include restraint device 874, once sheath 836 is from retracted position Extended position is moved to, the restraint device 874 is just used for preventing movement of the sheath 836 from extended position to retracted position.In peace During full sheath 836 moves to extended position from retracted position, the nearside projection 876 of safety shield 836 is passed through in housing 832 And/or in hub 864（Such as in coasting mechanism 816）Constraint notch 878 advance.

Constraint notch 878 can include：Gable 880, is configured to allow for the nearside projection 876 of safety shield 836 Easily pass through it；With attachment surface 882, once be configured to safety shield 836 has moved to extended position from retracted position Occur, the nearside projection 876 for just preventing safety shield 836 is reentered.By this way, once safety shield 836 The patient end 844 of shielding intubation 834, safety shield 836 cannot reenter housing 832.

In one embodiment, when safety shield 836 is in retracted position, flash chamber 898 is at least for doctor It is partially visible.Correspondingly, a part for sheath 836, such as Part II 812, can be by transparent material and/or trnaslucent materials Build, so as to flash chamber 898 is visible by it.

Figure 87-91 describes an alternative embodiment of the invention, and wherein collection assembly 930 is analogously built with described above Make, be a difference in that the construction and safety shield 936 of safety shield 936 for the mode of connection of housing 932.Needle assemblies 930 1 As include：Intubation 934, is associated with housing 932；With safety shield 936, be suitable to device during use and/or back hub The security mask of disk 964.Needle assemblies 930 also include wherein hub 964, and the hub 964 is used for support inserting tubes 934, and limits Determine flash chamber 998, as previously described.

In the embodiment represented in Figure 87-91, safety shield 936 includes suspension arm 940, and the suspension arm 940 is attached to On the outer surface 942 of housing 932.Suspension arm 940 can include multiple extensible sections 948, such as be connected to the second extensible section 950 On the first extensible section 944.In one embodiment, the first extensible section 940 pivotally or can be hingedly connected to hang Put in the foundation 952 of arm 940, such as by pivot 956, it is allowed to which the first extensible section 944 is relative to the pivot of foundation 952 Turn.In another embodiment, the second extensible section 950 pivotally or can be hingedly connected in the first extensible section 944, Such as pass through pivot 956, it is allowed to which the second extensible section 950 is pivoted relative to the first extensible section 944.

In one embodiment, the suspension arm 940 of sheath 936 is oriented on the first side of intubation 934.In another enforcement In example, sheath 936 includes the second suspension arm 970, and such as similar description, the second suspension arm 970 is the second of intubation 934 Orient on side, the second side is substantially relative with the first side.In a further embodiment, suspending the suspension arm 970 of arm 940 and second can be with Connection, such as passes through connector 972.In another embodiment, suspending the suspension arm 970 of arm 940 and second can be by least one Pivot 956 connects.In a further embodiment, pivot 956 can be for being used less than being hinged for 180 degree.

In one embodiment, the orientation for suspending the suspension arm 970 of arm 940 and second ensures, when sheath is in retracted position Shi Rongyi watches flash chamber 998.In retracted position, as shown in Figure 87, section 948 is may extend away fixed in generally laterally orientation To so as to the first distally alignment end 976 that may extend away section 944 and the second nearside that may extend away section 950 are directed at end 978 and are spaced apart. In one embodiment, the second extensible section 950 is deviateed at the distally alignment end 976 of the first extensible section 944 in lateral orientation Nearside alignment end 978, or be positioned in the different fore-and-aft plane for leaving it.In a further embodiment, first can prolong At least one of nearside alignment end 978 of the extensible section 950 in distally alignment end 976 and second of section 944 is stretched in lateral orientation The middle mobile axis W for deviateing sheath 936.

Safety shield 936 is by artificial for releasing parts 982 on the direction by shown in arrow H of expression in Figure 87 The applying of applying power, can move to extended position from retracted position.In the position that part extends, as shown in fig. 88, base The promotion forward of plinth part 952 starts the first extensible section 944 to pivot around pivot 956, until proximal end 960 reaches summit position Put（Represent in Figure 88）.As shown in Figure 89, the motion of the first extensible section 944 makes the second extensible section by pivot 956 950 advance.Such motion can forward be transported by the continuation of releasing parts 982 on the direction of arrow H represented in Figure 87 Move and complete, this causes the motion of foundation 952, the foundation 952 pivots the first extensible section 944 again.Selectively, Extensible section 948 can be built by having resilient material, so as to realize automatically once the first extensible arrival of section 944 summit Motion, is consequently formed the mechanism for automatically continuing motion.In order to adapt to this motion, the free end of the second extensible section 950 986 advance along mobile axis W（Represent in Figure 87）.

In fully extended position, as shown in Figure 91, when intubation 934 is in the shielding orientation of intubation 934, first can The extensible section 950 in extension 944 and second is relative to each other oriented along identical fore-and-aft plane in general parallel orientation orientation.Complete In fully extended position, extensible section 948 is substantially longitudinally directed, so as to the distally of the first extensible section 944 is directed at end 976 substantially It is adjacent end 978 to be directed at the nearside of the second extensible section 950.In one embodiment, the distally alignment of the first extensible section 944 End 976 is directed at end 978 along the nearside of the extensible section 950 of identical fore-and-aft plane W contacts second, as shown in Figure 91.

Safety shield 936, the specifically first extensible section 944 and second may extend away section 950, and it is any appropriate to have Size and construction, so as to when safety shield 936 is in extended position, they are suitable to shield intubation 934, and specifically shield Cover its puncture end.Patient's blood vessel is going in intubation 934（It is not shown）Inside while, or from patient After removing intubation 934, safety shield 936 can launch in intubation 934.Once sheath 936 is moved from retracted position To extended position, locking mechanism as being similar to description here, can also be used to prevent sheath 936 from extended position to contracting The movement that return is put.

In one embodiment, in retracted position and extended position and in partially extended position, flash chamber 998 can be visible for doctor.In another embodiment, safety shield 936 is from retracted position to extended position Movement completes not hinder the observation to flash chamber 998.In such configuration, the pivotal path of safety shield 936 is away from streamer The observation path of chamber 998.For example, pivot 956 can be positioned on the base section of needle assemblies 930, so as to not hinder by curing It is an apprentice of top directly to observe flash chamber 998.

Figure 92-93 describes an alternative embodiment of the invention, and wherein needle assemblies 1030 are similar with described above, different Part is the construction and safety shield 1036 of safety shield 1036 for the mode of connection of housing 1032.Needle assemblies 1030 are typically wrapped Include：Intubation 1034, is associated with housing 1032；With safety shield 1036, the during use and/or afterwards intubation in device is suitable to 1034 security mask.Needle assemblies 1030 also include hub 1064, and the hub 1064 is used for support inserting tubes 1034, and wherein Flash chamber 1098 is limited, as previously described.At least a portion of hub 1064 and flash chamber 1098 is by contracting The part of safety shield 1036 during return is put is visible.

In one embodiment, sheath 1036 includes suspension arm 1006, and the suspension arm 1006 is from the represented in Figure 92 One position in Figure 93 represent the second place be moveable, in the first position, suspension arm 1006 generally perpendicular to The longitudinal axis S of intubation 1034（Represent in Figure 92）, in the second place, suspend longitudinal axis of the arm substantially along intubation 1034 Line S is orientated.In one embodiment, suspending arm 1006 can include Part I 1008 and Part II 1010, between them Pivotally or hingedly connect.

A part for sheath 1036 is suitable in the extended position represented in Figure 93, is at least partly surrounded（As circumferentially Surround）At least a portion of the end of intubation 1034.In one embodiment, when safety shield 1036 is in retracted position, Flash chamber 1098 is at least partly visible for doctor.In retracted position, Part I 1008 and Part II 1010 Relative to intubation 1034 axis with generally vertically azimuthal orientation, and be generally parallel to one another in extended position.Sheath can be with Including circular portion 1088, the circular portion 1088 around intubation 1034 a part circumferentially.In one embodiment, one Denier Part I 1008 and Part II 1010 press general parallel orientation alignment of orientation, and circular portion 1088 just can be in suspension arm 1006 Upper advance, such as on the hinge 1090 of connection Part I 1008 and Part II 1010, thus by the lock into place of hinge 1090.

In another embodiment, another optional hinge assembly reality that the present invention is represented in Figure 94-106 is represented Apply example.Needle assemblies 30c1 is generally comprised：Needle construction 32c1, is associated with needle stand 42c1；With safety shield 64c1, it is suitable in device Use after needle construction 32c1 security mask.Needle assemblies 30c1 also includes：Hub 58c1, for support needle construction 32c1 and Flash back indicator 60c1 therein is limited to, as previously described.

In the embodiment represented in Figure 94-106, safety shield 64c1 can include that the first suspension arm 3000 and second hangs Arm 3002 is put, the second suspension arm 3002 is in substantially parallel relationship to the first suspension arm 3000.The first suspension suspension arm of arm 3000 and second 3002 are linked together by connection surface 3004, and the connection surface 3004 is suspended generally perpendicular to the first suspension arm 3000 and second Arm 3002.Safety shield 64c1 has：Proximal end 3006 is adjacent with needle stand 42c1；With distal end portion 3008, with the phase of proximal end 3006 It is right.At least a portion of the proximal end 3006 of safety shield 64c1 is pivotally connected on needle stand 42c1.Preferably, safety shield The proximal end 3006 of 64c1 is connected on needle stand 42c1 by two relative pivots 3010.In a further embodiment, safety protective Set 64c1 is connected on the anterior cone 3012 of needle stand 42c1 by pivot 3010, and these pivots 3010 extended opposed webs arm 3014, the opposed webs arm 3014 is connected on anterior cone 3012, and the longitudinal axis along needle stand 42c1 is oriented.

The permission safety shield 64c1 of pivot 3010 is with rotating manner relative to needle stand 42c1 from shown in Figure 98-101 Retracted position is movably pivoted to the extended position shown in Figure 102-104.In one embodiment, safety shield 64c1 Sheath engaging zones 3016 can be included, the sheath engaging zones 3016 are adjacent with proximal end 3006 in connection surface 3004, With the profile substantially corresponding with the profile of the outer surface 3018 of needle stand 42c1 and/or the outer surface 3018 of anterior cone 3012. In such configuration, sheath engaging zones 3016 can be against the part placement of needle stand 42c1 in retracted position.

As shown in Figure 97, hub 58c1 can include forward hub portion 3026 and rear hub portion 3028, after this Portion's hub portion 3028 is joined on the first hub portion 3026.Forward hub portion 3026 can have around flash back indicator The generally conical shape of 60c1 arrangements.In one embodiment, at least a portion of forward hub portion 3026 distad surpasses The anterior cone 3012 of more needle stand 42c1 extends.In another embodiment, at least a portion of forward hub portion 3026 has The profile corresponding with the profile of the anterior cone 3012 of needle stand 42c1.The rear hub portion 3028 of hub 58c1 can include disk Structure, the dish structure can be sized to contact the inner periphery of needle stand 42c1, to prevent vacuum blood collecting tube（It is not shown） Surmount its advance.At least a portion of needle construction 32c1 can extend the forward hub portion 3026 and rear hub of hub 58c1 Disc portion 3028.Although hub 58c1 can be provided in collection assembly as integral member, in construction may be selected, hub 58c1, including forward hub portion 3026 and rear hub portion 3028, and needle construction 32c1 can be separately formed, and It is subsequently assembled in collection assembly 30c1.

In one embodiment, needle assemblies 30c1 can be provided with can remove IV needle shields 3020, and this can remove IV needle shields 3020 at least a portion for covering needle construction 32c1, such as cover at least a portion of distal needle part 34c1.In one embodiment In, as shown in Figure 97, needle shield 3020 can be sized to, the forward hub portion 3026, needle stand 42c1 in hub 58c1 Extend in front portion cone 3012, at least a portion of flash back indicator 60c1 and/or hub 58c1.Needle shield 3020 is using it It is front to be removed from needle assemblies 30c1 by the typical artificial pressure that applies.

Figure 97 is referred again to, in another embodiment, needle shield 3020 can be provided with raised projections 3022, the raised projections 3022 are arranged on the outer surface 3024 of needle shield 3020.In one embodiment, raised projections 3022 were around needle shield 3020 weeks To arrangement.In another embodiment, raised projections 3022 are corresponding with the notch 3030 in safety shield 64c1, so as to pin Sheath 3020 unexpectedly can not discharge from needle assemblies 30c1, until safety shield 64c1 is positioned in retracted position, such as Figure 98- Shown in 101.

Safety shield 64c1 can be sized to any size, and these sizes are adapted to allow for safety shield 64c1 and are retracting Needle construction 32c1 is pivoted away from position, as shown in Figure 98-101, to allow doctor to engage needle construction 32c1 with patient, And to needle construction 32c1 pivots and it is shielded in extended position, specifically, the end of distal needle part 34c1 is such as schemed Shown in 102-104.In one embodiment, safety shield 64c1 can pivot away from the enough angle of axis of needle construction 32c1 Degree, to allow doctor to watch flash back indicator 60c1 and/or hub 58c1 in retracted position.In another embodiment, pacify Full sheath 64c1 is made up of transparent and/or trnaslucent materials, to allow doctor to observe flash back indicator 60c1 and/or hub by it Disk 58c1.

Once distal needle part 34c1 takes out from the patient, needle assemblies 30c1 just can be moved to from retracted position Extended position.In one embodiment, the first suspension suspension arm 3002 of arm 3000 and second of safety shield 64c1 can be built Press-fit locking is formed into at least a portion of forward hub portion 3026, anterior cone 3012 and/or needle stand 42c1.This is prevented Once the initial movement from retracted position to extended position has occurred and that safety shield 64c1 is re-moved to retracted position.Such as Shown in Figure 105-106, each can include inward slant limiter 3032 to the first suspension suspension of arm 3000 and second arm 3002, The inward slant limiter 3032 is arranged to adjacent with the pivot 3010 at the near-end 3006 of safety shield 64c1.Incline and limit Device 3032 includes inclined surface 3036 and attachment surface 3038.Forward hub portion 3026 can also include being limited for engagement angled Multiple nibs 3034 of device processed 3032.In one embodiment, when the safety shield 64c1 of needle assemblies 30c1 is moved from retracted position When moving extended position, the nib 3034 of the engagement front hub portion 3026 of tilt limiter 3032 of safety shield 64c1.Tool Say, the engagement nib 3034 of attachment surface 3038 body, and prevent the later motion of safety shield 64c1.In one embodiment In, nib 3034 is positioned on the distal end 3050 of hub 58c1.In another embodiment, tilt limiter 3032 is positioned at peace On full sheath 64c1 at the position away from pivot 3010, for the nib being accordingly bonded on the distal end 3050 of hub 58c1 3034.Selectively, anterior cone 3012 can also include that multiple nib 3034a, these nibs 3034a are used for engaging safety shield The tilt limiter 3032 of 64c1.In yet another embodiment, tilt limiter 3032 is positioned at the long side of safety shield 64c1 On 3052, and can extend from the proximal direction of pivot 3010.Correspondingly, the engagement of safety shield 64c1 and hub 58c1 Can occur on the long side 3052 of needle assemblies 30c1（Bottom sides）Place.Movement of the tilt limiter 3032 on nib 3034 by Realize in typical artificial pressure.As shown in Figure 106, safety shield 64c1 can optionally include biased element 3040, the biased element 3040 is used for that further forward hub portion 3026 is fixed in safety shield 64c1.Thus, safety The latch-up structure of sheath 64c1 engages at least a portion of flash chamber, and the flash chamber is limited in hub 58c1.At one In embodiment, the latch-up structure of safety shield 64c1 is bonded at least a portion of the housing at flash chamber distal position, such as Hub 58c1.

Figure 107-121 describes another optional hinge assembly embodiment of the present invention.Needle assemblies 5000, such as Figure 107- Shown in 113, generally comprise：Needle construction 32c2, is associated with hub 58c2；With safety shield 64c2, hub 58c2 is connected to On, and it is suitable to the security mask of needle construction 32c2 after use of the device.In one embodiment, needle assemblies 5000 can be wrapped Include the feature of other known needle assemblies, the known needle assemblies have be hinged safety shield, such as in United States Patent (USP) disclosure Those disclosed in No.2005/0187493, thus the entire disclosure of the Patent Publication by reference to including.

Needle construction 32c2 can include distal needle part 5002 and proximal needle part 5004.Distal needle part 5002 and nearside Pin part 5004 can be separate pin, both represent pin intubation, and the pin intubation limits the center bor extended through it 5006.Proximal needle part 5004 represents the non-patient end of needle construction 32c2, and the non-patient end supplies vacuum blood collecting tube（Do not show Go out）Puncture be used.Proximal needle part 5004 can be covered by elastomer multisample set 5008, the elastomer multisample set 5008 Can be pierced through by the tip of the proximal needle part 5004 of needle construction 32c2.Distal needle part 5002 represents the patient of needle construction 32c2 End, and can be with bevel to limit puncture end, the puncture end is used for the skin and the arteries and veins into patient of puncture patient Guard system.

Hub 58c2 can include forward hub portion 5010 and rear hub portion 5012, and can support through it Needle construction 32c2.In one embodiment, distal needle part 5002 can be integral with forward hub portion 5010, and closely Side pin part 5004 can be integral with rear hub portion 5012.Forward hub portion 5010 and the structure of rear hub portion 5012 Cause pairing engagement.Forward hub portion 5010 can include projection 5014, such as protuberance annular ring, for engaging and rear hub The integral corresponding recess 5016 in part 5012.In another embodiment, forward hub portion 5010 and rear hub portion 5012 can be with Jing adhesives or solder joints together.Once assembling, hub 58c2 just limits wherein flash back indicator 60c2, As previously described.

Hub 58c2 can also include collar 5018, and the collar 5018 is used at least around safety shield 64c2 Divide, such as the pivot 5020 of safety shield 64c2, as described herein before.In one embodiment, forward hub portion 5010 include the first collar portion 5022, and rear hub portion 5012 includes the second collar portion 5024.First collar part Divide 5022 can include substantially c shapes region 5028, the c shapes region 5028 is used for accommodating the connection shaft of safety shield 64c2 wherein 5026 are held, is represented in Figure 112 and 114.Linking bearing 5026 can be integral with safety shield 64c2.Link bearing 5026 Can with a part of hub 58c2, such as the first collar portion 5022 and/or the second collar portion 5024, it is integral.May be selected Ground, linking bearing 5026 can be provided separately from, and assemble with safety shield 64c2 and/or hub 58c2 later.Connection shaft Holding 5026 can extend between the first of safety shield 64c2 the suspension suspension arm 5046 of arm 5044 and second, such as institute in Figure 115 Show.Second collar portion 5024 can include cap region 5030, and the cap region 5030 has the connection shaft with safety shield 64c2 Hold 5026 substantially corresponding interior surfaces 5032.First collar portion 5022 can include projection 5034, and the projection 5034 is used To engage the corresponding recess 5036 integral with the second collar portion 5024.Correspondingly, in one embodiment, forward hub portion 5010 are divided also to engage the first collar portion 5022 and the second collar portion 5024 with the engagement of rear hub portion 5012.Another In individual embodiment, collar 5018 is positioned substantially on the top surface of hub 58c2, to allow safety shield 64c2 equally also to connect It is connected on the top surface of hub 58c2.

Refer again to Figure 107-113, nearside IV needle shields 5038 and distally IV needle shield 5040 before the use can be respectively There is provided on proximal needle part 5004 and distal needle part 5002, as described herein.

During use, nearside IV needle shields 5038 can be removed proximally pin part 5004, and needle stand 42c2, be represented In Figure 115-121, may be inserted on proximal needle part 5004, and engage with least a portion of hub 58c2.At one In embodiment, needle stand 42c2 is engaged with a part for rear hub portion 5012.

In another embodiment, represent that the link bearing 5026 of safety shield 64c2 can include notch in Figure 114 5042, the notch 5042 is used for that safety shield 64c2 is maintained in assigned position.For example, notch 5042 can in retracted position So that frictionally safety shield 64c2 is maintained in collar 5018 by predetermined angular.This allows doctor that institute is pressed during medical procedure Angle positioning security sheath 64c2 is needed, and without paying attention to the accidental closing or slip of safety shield 64c2.

As shown in Figure 115-121, needle assemblies 30c2 can be moved in extension bit from the retracted position represented in Figure 114 Put, in the retracted position, in order to be close to the purpose of patient, distal needle part 5002 is not shielded, in the extended position, far Side pin part 5002 by security mask in order to avoid exposure, as described herein.Reference picture 107-121, in another enforcement In example, safety shield 64c2 can include thumb press region 64c2a, for enabling a physician to pivot safety shield 64c2, with A part for nearside IV needle shields 5038 was engaged before the skin puncture of patient.In one embodiment, thumb press region 64c2a surmounts at least in part safety shield 64c2 extensions, to enable a physician to easily with single finger or thumb contact thumb Refer to area pressed 64c2a.

In an optional embodiment, as shown in Figure 122, collection assembly 130w can include safety shield 64w, Safety shield 64w can include first end 138w, and first end 138w has the first suspension arm 132w and the second suspension arm 134w, second suspension arm 134w is in substantially parallel relationship to the first suspension arm 132w.First suspension arm 132w and the second suspension arm 134w Can link together.First suspension arm 132w and the second suspension arm 134w can have the area being substantially the same.Safety shield 64w has end 140w, and end 140w is connected on needle stand 42w by least one pivot 142w.Preferably, safety shield The end 140w of 64w is connected on needle stand 42w by two pivot 142w.Exemplary pivot is in United States Patent (USP) disclosure No.2005/187, described in 493, the full content of the Patent Publication is incorporated herein by.

In one embodiment, pivot 142w can include：Projection, the second end 140w one with safety shield 64w Ground is formed；With correspondence recess, in being limited to the distal end of needle stand 42w.In another embodiment, pivot 142w can include：It is recessed Mouthful, it is limited in the second end 140w of safety shield 64w；With correspondence recess, it is limited in the distal end of needle stand 42w.Another In individual embodiment, the first pivot 142w may be arranged on the first side of the distal end of needle stand 42w, and the second pivot 142w can be arranged On the second side of the distal end of needle stand 42w, first and second sides of needle stand 42w are substantially relative to each other.Pivot 142w allows safety Sheath 64w is pivoted to extended position with rotating manner relative to needle stand 42w from the retracted position as shown in Figure 122, such as in the past As description.

In yet another embodiment of the present invention, represent that in Figure 123-125, needle assemblies 1130 include specimen collection container Seat 1101, the specimen collection container seat 1101 has pierceable or can pierce sheath 1102, and this can pierce or can pierce sheath 1102 are arranged on the near-end 1103 of specimen collection container seat 1101, to provide before the use in specimen collection container seat 1101 Inside in gnotobasis.In one embodiment, sheath 1102 is can pierce or can pierced by wherein with perforate section Paper, polymer and/or thin metal film make, these perforate sections can apply pressure and pierce through by standard intraocular.Using In, doctor by can pierce or can pierce sheath 1102 by any conventionally known specimen collection container 1105, and such as blood is received Collector, in being inserted into the near-end 1103 of specimen collection container seat 1101.

Then needle assemblies 1130 can be used by any mode for describing herein before, with carry out medical procedure and/or Intubation 1134 is shielded after use.After usage, can pierce or can pierce sheath 1102 can keep being attached to sample collection On container holder 1101, with provide needle assemblies 1130 use clearly indicate.Correspondingly, including can pierce or can pierce sheath 1102 needle assemblies 1130 are provided to doctor and clearly have been used by and/or use indicator.It is described herein to can pierce or pierce Cross sheath 1102 to be suitable to be used for above-mentioned collection assembly any one.It is also contemplated to, separate, removable liner（It is not shown） Can be with as by the way that adhesive can be removed, being fixed on the outer surface of sheath 1102.Such a can remove liner before the use Other aseptic and isolation protection is provided.In addition, can pierce or sheath 1102 can be pierced can apply to specimen collection container seat 1101 near-end 1103, as pre-packaged device, in addition it is also necessary to outer packaging in addition.

Figure 126-131 shows yet another embodiment of the present invention, wherein, the housing 7000 of needle assemblies, represent Figure 130- In 131, as described herein before, including：Foundation 7002, represents in Figure 126-127；And hub portion 7004, represent in Figure 128-129, it is engageable with foundation 7002.Reference picture 126-127, foundation 7002 has remote End 7006 and near-end 7008, side wall 7010 extends between them.In one embodiment, side wall 7010 limits at least one and opens Mouth 7012, by the opening 7012, can receive the Part I 7016 of hub 7004, represent in Figure 128.In another reality In applying example, opening 7012 is adapted to allow for the Part I 7016 of hub 7004, and from the inside 7022 of foundation 7002 side is passed through The position that wall 7010 is led to outside the inside 7022 of foundation 7002.In another embodiment, side wall 7010 limits second Opening 7014, by second opening 7014, can receive the Part II 7018 of hub 7004, represent in 128.Another In individual embodiment, the first opening 7012 of foundation 7002 can be in substantially relative bearing relative to the second opening 7014 pairs Standard, so as to the first opening 7012 and the second opening 7014 along public through axis Z alignments, as shown in Figure 126.In other reality In applying example, the side wall 7010 of foundation 7002 can include releasing parts opening 7020, by the releasing parts opening 7020, Can receive releasing parts 7040, represent in Figure 130-131 and as previously described.

As shown in Figure 128-129, hub 7004 can include Part I 7016, and the Part I 7016 is in substantially footpath Extend from the body part 7024 of hub 7004 in orientation.In another embodiment, hub 7004 can include second Divide 7018, the Part II 7018 extends in essentially radially orientation from the body part 7024 of hub 7004, and substantially It is aligned relative to Part I 7016 in relative bearing, so as to Part I 7016 and Part II 7018 are at least in part along public Coaxial line Y is aligned, as shown in Figure 128.In another embodiment, common axis Y of hub 7004 can be with foundation 7002 can be aligned through axis Z, represents in Figure 126.

As shown in Figure 130-131, hub portion 7004 be in the foundation 7002 it is at least partly insertable, so as to The Part I 7016 of hub 7004 extended at least in part opening 7012, and the opening 7012 is limited to foundation 7002 In side wall 7010.In another embodiment, hub portion 7004 be in the foundation 7002 it is at least partly insertable, from And the Part I 7016 of hub portion 7004 extended at least in part opening 7012, the opening 7012 is limited to foundation In 7002 side wall 7010, and the Part II 7018 of hub extended at least in part the second opening 7014, and this second is opened Mouth 7014 is limited in the side wall 7010 of foundation 7002.In yet another embodiment, hub portion 7004 can be by near End 7008 can be plugged in the inside 7022 of foundation 7002.In yet another embodiment, Part I 7016 and second At least one of points 7018 can bend against the interior wall 7026 of the inside 7022 of foundation, such as in hub portion 7004 be inserted in foundation 7002 during at the part adjacent with near-end 7008.In another embodiment, first Points 7016 and Part II 7018 at least one include can gripping region 7030, when hub portion 7004 is arranged in foundation When in 7002, this can gripping region 7030 allow users to easily contact housing 7000.In one embodiment, can catch Region 7030 includes multiple ribs 7032.

While certain embodiments of the present invention have been described in detail, but those skilled in the art will recognize that, this The various modifications and changes for those details can be produced under the disclosed overall enlightenment lectured.Present example described herein Mean to be merely illustrative, and for the scope of the present invention is not restricted, the scope of the present invention is by appended Claims and its any and all equivalent way are broadly given completely.It is various without departing from scope and spirit of the present invention It is that other embodiments will be apparent for those skilled in the art and easy to perform.

Claims

1. a kind of needle assemblies, including：

Housing, including flash chamber, and with proximally and distally, the near-end can be engaged with specimen collection container；

Intubation, the patient end with restriction cannula interior, non-patient end and the side wall extended between patient end and non-patient end, The patient end of the intubation stretches out at least in part from the distal end of the housing, and the cannula interior with it is described Flash chamber is in fluid communication；And

Sheath, constraint engages with a part for the housing, and can be on the patient end of the intubation from retracted position It is axially moveable to extended position, in the retracted position, exposes the patient end, in the extended position, the patient end Shielded by least a portion of the sheath, wherein, when the sheath is in the retracted position, the sheath is relative to housing Be positioned to or the protector configurations be at least a portion for making the flash chamber it is visible,

Wherein, the sheath includes suspension arm, and the suspension arm includes multiple extensible sections, and the suspension arm is relative to the housing It is visible to be oriented the flash chamber when the sheath is in the retracted position.

2. needle assemblies according to claim 1, wherein, the extensible section is substantially transversely fixed in the retracted position To, and be substantially longitudinally directed in the extended position.

3. needle assemblies according to claim 2, wherein, connect pivotally or hingedly between the plurality of extensible section.

4. needle assemblies according to claim 2, wherein, the suspension arm is oriented on the first side of the intubation, and Also include the second suspension arm, the second suspension arm is oriented on the second side of the intubation, second side is substantially with described the Side is relative.

5. needle assemblies according to claim 1, wherein, the sheath of axial movement is on the patient end of the intubation from retraction Position to extended position intussusception is moved.

6. needle assemblies according to claim 1, wherein, in the retracted position, the flash chamber is by the shield At least a portion of set is visible.

7. needle assemblies according to claim 6, wherein so that the part of the visible sheath of the flash chamber is It is bright or translucent.

8. needle assemblies according to claim 1, wherein, the sheath includes watch window, and in the retracted position In, the flash chamber is visible by the watch window.

9. needle assemblies according to claim 8, wherein, the patient end of the intubation includes inclined-plane, and described The position of the watch window in sheath is corresponding with the orientation on the inclined-plane.

10. needle assemblies according to claim 1, wherein, the sheath is at least partly surrounded in the extended position The patient end of the intubation.

11. needle assemblies according to claim 1, wherein, the side wall of the intubation be limited to the cannula interior with The opening extended between the flash chamber.

12. needle assemblies according to claim 1, wherein, the intubation includes at least two points of pin parts opened.

13. needle assemblies according to claim 9, wherein, the intubation includes the disease being in fluid communication with the flash chamber People's pin and the non-patient pin being in fluid communication with the flash chamber.

14. needle assemblies according to claim 13, wherein, the patient needle is at least in part from the described remote of the housing End is stretched out, and the non-patient pin extends from the patient needle along substantially proximal direction.

15. needle assemblies according to claim 1, wherein, the flash chamber is formed on of the housing In point.

16. needle assemblies according to claim 1, wherein, the housing also includes supporting at least a portion of the intubation Hub.

17. needle assemblies according to claim 16, wherein, the flash chamber is integrally formed with the hub.

18. needle assemblies according to claim 1, also including porous vent, the porous vent is arranged in the streamer The flash chamber is separated into first chamber and second chamber by within the chamber, the porous vent.

19. needle assemblies according to claim 18, wherein, the first chamber and the second chamber are configured to, in institute When stating patient end and being inserted in patient body, blood is flowed by the intubation, and is flowed in the first chamber, and not close The porous vent is sealed, and when emptying specimen collection container is applied in the non-patient end of the intubation, blood Liquid is extracted out from the first chamber, and air is extracted out from the second chamber, thus relative to the outside of the flash chamber Environment forms negative pressure in the second chamber.

20. needle assemblies according to claim 19, wherein, the porous vent includes multiple micropores, for causing blood Micropore described in liquid Jing is from the first chamber by the second chamber.

21. needle assemblies according to claim 19, wherein, the porous vent is the porous formed by hydrophobic material At least one in the porous plug that plug, check valve and the water wetted material expanded during by with contacting blood are formed.

22. needle assemblies according to claim 1, wherein, the flash chamber includes and the outside around the needle assemblies The ventilating mechanism of environmental communication.

23. needle assemblies according to claim 1, wherein, at least one masked segment of the sheath is in the retraction position Put and be constraint bonded in the interior section of the housing, and the masked segment of the sheath is in the extended position In stretch out from the interior section of the housing.

24. needle assemblies according to claim 20, wherein, the interior section of the housing is surrounded and is limited in the housing Specimen collection container receive port circumferentially.

25. needle assemblies according to claim 21, wherein, the interior section and the sample collection of the housing hold It is coaxial that device receives port.

26. needle assemblies according to claim 1, wherein, the housing includes Part I and Part II, described first Part is in the distally of the Part II, and wherein, the sheath is all arranged in described first in the retracted position In partial inside, and specimen collection container receives port to be limited in the Part II.

27. needle assemblies according to claim 26, wherein, the Part I and the Part II of the housing are total to With formation.

28. needle assemblies according to claim 26, wherein, the Part I and the Part II point of the housing Turn up the soil to be formed and be subsequently assembled.

29. needle assemblies according to claim 26, wherein, the Part I of the housing limits watch window, leads to The watch window is crossed, the sheath is visible when in the retracted position.