CN103636670B - Sterilization composition containing Dufulin and enestroburin - Google Patents
Sterilization composition containing Dufulin and enestroburin Download PDFInfo
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- CN103636670B CN103636670B CN201310576203.0A CN201310576203A CN103636670B CN 103636670 B CN103636670 B CN 103636670B CN 201310576203 A CN201310576203 A CN 201310576203A CN 103636670 B CN103636670 B CN 103636670B
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- enestroburin
- fluorine phosphorus
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- bactericidal composition
- poison
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- VMNULHCTRPXWFJ-UJSVPXBISA-N enoxastrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1CO\N=C(/C)\C=C\C1=CC=C(Cl)C=C1 VMNULHCTRPXWFJ-UJSVPXBISA-N 0.000 title claims abstract description 66
- 239000000203 mixture Substances 0.000 title claims abstract description 52
- 230000001954 sterilising effect Effects 0.000 title abstract 5
- 238000004659 sterilization and disinfection Methods 0.000 title abstract 5
- CLASFMUIFVKHQI-UHFFFAOYSA-N n-[diethoxyphosphoryl-(2-fluorophenyl)methyl]-4-methyl-1,3-benzothiazol-2-amine Chemical compound N=1C2=C(C)C=CC=C2SC=1NC(P(=O)(OCC)OCC)C1=CC=CC=C1F CLASFMUIFVKHQI-UHFFFAOYSA-N 0.000 title abstract 4
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- 239000000843 powder Substances 0.000 claims description 36
- 238000009736 wetting Methods 0.000 claims description 36
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- 239000002131 composite material Substances 0.000 claims description 19
- 239000004480 active ingredient Substances 0.000 claims description 17
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- 231100000331 toxic Toxicity 0.000 claims description 11
- 230000002588 toxic effect Effects 0.000 claims description 11
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- 241000607479 Yersinia pestis Species 0.000 claims 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 9
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- 239000003814 drug Substances 0.000 description 54
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- 241000208125 Nicotiana Species 0.000 description 21
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 21
- JHIPUJPTQJYEQK-ZLHHXESBSA-N orysastrobin Chemical compound CNC(=O)C(=N\OC)\C1=CC=CC=C1CO\N=C(/C)\C(=N\OC)\C(\C)=N\OC JHIPUJPTQJYEQK-ZLHHXESBSA-N 0.000 description 20
- 241000700605 Viruses Species 0.000 description 19
- CWVRPJSBNHNJSI-XQNSMLJCSA-N coumoxystrobin Chemical compound C1=C2OC(=O)C(CCCC)=C(C)C2=CC=C1OCC1=CC=CC=C1\C(=C/OC)C(=O)OC CWVRPJSBNHNJSI-XQNSMLJCSA-N 0.000 description 18
- 241000209094 Oryza Species 0.000 description 17
- 235000007164 Oryza sativa Nutrition 0.000 description 17
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- 230000000694 effects Effects 0.000 description 16
- 150000001875 compounds Chemical class 0.000 description 15
- 229940079593 drug Drugs 0.000 description 14
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- 241000894006 Bacteria Species 0.000 description 13
- 150000002148 esters Chemical class 0.000 description 13
- 150000002923 oximes Chemical class 0.000 description 13
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- 238000000034 method Methods 0.000 description 11
- 239000000945 filler Substances 0.000 description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 239000003899 bactericide agent Substances 0.000 description 8
- 238000002156 mixing Methods 0.000 description 6
- 238000012216 screening Methods 0.000 description 6
- 241001330975 Magnaporthe oryzae Species 0.000 description 5
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- 230000003449 preventive effect Effects 0.000 description 3
- ONCZDRURRATYFI-TVJDWZFNSA-N trifloxystrobin Chemical compound CO\N=C(\C(=O)OC)C1=CC=CC=C1CO\N=C(/C)C1=CC=CC(C(F)(F)F)=C1 ONCZDRURRATYFI-TVJDWZFNSA-N 0.000 description 3
- 241000233679 Peronosporaceae Species 0.000 description 2
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- 238000001228 spectrum Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 241000235349 Ascomycota Species 0.000 description 1
- 241000221198 Basidiomycota Species 0.000 description 1
- 102000018832 Cytochromes Human genes 0.000 description 1
- 108010052832 Cytochromes Proteins 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- 239000005784 Fluoxastrobin Substances 0.000 description 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
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- 240000000203 Salix gracilistyla Species 0.000 description 1
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- 240000003768 Solanum lycopersicum Species 0.000 description 1
- 229930182692 Strobilurin Natural products 0.000 description 1
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- 239000002253 acid Substances 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
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- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- UFEODZBUAFNAEU-NLRVBDNBSA-N fluoxastrobin Chemical compound C=1C=CC=C(OC=2C(=C(OC=3C(=CC=CC=3)Cl)N=CN=2)F)C=1C(=N/OC)\C1=NOCCO1 UFEODZBUAFNAEU-NLRVBDNBSA-N 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 210000004602 germ cell Anatomy 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000008811 mitochondrial respiratory chain Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- -1 monomethyl benzothiazolyl Chemical group 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 150000008298 phosphoramidates Chemical class 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
A disclosed sterilization composition containing Dufulin and enestroburin is prepared by compounding active components Dufulin and enestroburin with a weight ratio of 40:1-1:40, the sum of Dufulin and enestroburin accounts for 5-80% by weight of the sterilization composition, and the sterilization composition can be prepared into routine dosage forms such as a wettable powder, a suspending agent, water-dispersible granules and the like. The composition is used to control crop diseases, and the sterilization composition provided by the invention has the advantages of being efficient, small in environmental pollution, capable of delaying generation of pathogen resistance, and the like.
Description
The application is application number: 201210215432.5, and the applying date is: 2012.06.27, and denomination of invention is: the divisional application of the bactericidal composition of toxic fluorine phosphorus and methoxy acrylic bactericide.
Technical field
The invention belongs to technical field of pesticide, relate to composition pesticide, relate to the bactericidal composition of a kind of toxic fluorine phosphorus and Enestroburin specifically.
Background technology
Poison fluorine phosphorus (N-[2 one (4 monomethyl benzothiazolyl)] one 2. amino-2-difluorophenyl-O, O-diethyl phosphonate) be the fluorine-containing phosphoramidate class new antiviral agents of novel structure, can by activating tobacco bigcatkin willow acid signal conduction path, improve the salicylic content of signaling molecule, thus promote the expression of downstream pathogenesis-related proteins; Anti-virus ability is obtained by evoking tobacco PAL, POD, SOD Defense Enzyme Activities; The invasion of virus to host is reduced by assembling TMV particle.Because this medicament is environmentally friendly, production technology simple, the more commercially available medicament of three-waste free pollution, production cost is low, simultaneously also with raising plant disease-resistant ability, therefore this medicament is expected to play larger effect in the integrated control viroses of plant.
Methoxy acrylic (strobilurins) bactericide is a class low toxicity, efficient, wide spectrum, systemic fungicide; there is protection, treatment and eradicant action; its mechanism of action acts on cytochrome compound; block the electron transfer process of germ mitochondrial respiratory chain; suppress the supply of germ cellular energy, make germ cell lack energy dead.This series bactericidal agent comprises oxime bacterium ester, SYP-3375, Enestroburin, orysastrobin etc., to germs such as Ascomycetes, Basidiomycetes, deuteromycetes and Oomycetes, all there is good activity, the diseases such as the powdery mildew of various crop, rust, downy mildew, epidemic disease, anthracnose can be prevented and treated.To crop, people and animals and beneficial organism safety, and with other conventional bactericide without cross resistance.But because action site is single, easily develop immunity to drugs, have powdery mildew produces resistance report to Fluoxastrobin etc. in Europe.
Methoxy acrylic bactericide described in technical solution of the present invention is specially:
Enestroburin (Enestroburin, SYP-Z071) is first methoxy acrylic bactericide of domestic-developed, by Shenyang Chemical Engineering Inst's exploitation in 1997 years.Have fungicidal spectrum wide, bactericidal activity is high, can prevent and treat the medicament of powdery mildew and downy mildew epidemic disease simultaneously.Also to scab, anthracnose, spot defoliation etc., there is extraordinary preventive effect.Toxicity is low, have good compatibility to environment.
Synergistic bactericidal composition not only can improve preventive effect greatly, reduces dosage, reduces costs, and phytopathogen can also be avoided to produce the generation speed of resistance and delaying drug resistance simultaneously, be solve current agricultural chemicals alone time resistance and a kind of effective means of Cost Problems.
Summary of the invention
The object of the invention is to overcome the dosing that above-mentioned single bactericide exists large, environmental pollution is serious, germ resistance produces the shortcomings such as speed is fast and provide a kind of bactericidal composition of efficient, safe toxic fluorine phosphorus.Under optimal proportion, composition has notable synergistic effect, ensureing the usage amount reducing medicament under optimum preventive effect, reducing costs, reducing the harm to environment, and is of value to and delays the drug-fast generation of germ.
Technical scheme of the present invention:
The bactericidal composition of toxic fluorine phosphorus and Enestroburin, active ingredient is malicious fluorine phosphorus and Enestroburin is composite forms, and the weight ratio of malicious fluorine phosphorus and Enestroburin is 40:1 ~ 1:40.
As preferred further, the weight ratio of described malicious fluorine phosphorus and Enestroburin is 20:1 ~ 1:20.
The percentage by weight that the weight summation of described malicious fluorine phosphorus and Enestroburin accounts for bactericidal composition gross weight is 5 ~ 80%, and preferred weight percent is 10 ~ 60%, and surplus is allow in agricultural chemicals to use and acceptable auxiliary element, auxiliary agent, solvent or filler.
Bactericidal composition of the present invention can adopt method known to those skilled in the art to be prepared into regular dosage form in the agricultural chemicals such as wetting powder, suspending agent, water dispersible granules.
The auxiliary agent used in bactericidal composition of the present invention comprises solvent, dispersant, emulsifier, stabilizing agent, antifreezing agent, wetting agent etc. and other is of value to the known substance that active ingredient is stablized in the formulation and drug effect plays, all various compositions that are conventional in pesticidal preparations or permission use, be not particularly limited, concrete composition and consumption are determined by simple experiment according to recipe requirements.
Product described in the invention can finished product preparation form provide, and namely in composition, each material mixes, and the composition of composition also can provide with unit dose form, directly directly mixes in bucket or tank, be then diluted to required concentration before using.
Bactericidal composition of the present invention is applied preventing and treating in the multiple diseases in various crop, and composition of the present invention can be used by common method, as cast, spraying, scatters, and its amount of application is with weather condition or crop condition change.
Advantage of the present invention:
1, bactericidal composition of the present invention is made up of the active ingredient that two kinds of mechanism of action are different, has obvious synergistic function, improve control efficiency after mixture, is also conducive to overcoming and delay the drug-fast generation of germ simultaneously.
2, bactericidal composition medicament mixture of the present invention decreases dosage, thus reduces cost and alleviate the pollution to environment, and safety is good, meets the security requirement of pesticidal preparations.
3, bactericidal composition provided by the present invention has good control efficiency to various crop multiple diseases.
Specific embodiment
The combination of active principles of different agricultural chemicals is made agricultural chemicals, is current development novel pesticide and the one of preventing and treating agriculturally resistance germ effectively and efficiently mode.After the pestsides synthesis of different cultivars, usually show three kinds of type of action: summation action, synergistic effect and antagonism.Compound synergic is well filled a prescription, and can significantly improve actual control efficiency, and reducing the usage amount of agricultural chemicals, thus delay the drug-fast generation speed of germ widely, is the important means of integrated control disease.
Inventor is by a large amount of screening tests, and find that malicious fluorine phosphorus and methoxy acrylic bactericide combine antagonism germ and have synergistic function significantly, and be not only the simple addition of two kinds of medicaments, this can know from following biologicall test example and find out.
Biologicall test example 1: malicious fluorine phosphorus and the composite Toxicity Determination to rice blast fungus of Enestroburin
Subjects: the rice blast fungus picking up from field
Test method: with reference to " People's Republic of China (PRC) agricultural industry criteria NY/T1154.7-2006 ", pot-culture method.Choose the rice seedlings in tri-leaf period that growth potential is consistent, every basin 2 young plant, each process selects 5 basins for examination rice seedling.Pyricularia oryzae is cultivated on tomato oat-agar cultures base, with spore under aseptic washing after product spore, makes 1 × 10
5the suspension of individual spore/mL, uniform spray inoculation, in on examination rice seedling, puts the moisturizing of black plastic bag and cultivates 24h after inoculation.After inoculation 24h, carry out chemicals treatment, each medicament arranges 5 concentration gradients, sprays under 50PSI pressure with Potter spray tower, the about 5mL of every basin.After spray medicine, rice seedling is placed in about 25 DEG C, cultivates under the condition of relative moisture >=90%, investigate the disease index of whole strain blade after 7d according to the morbidity grade scale of rice blast, and calculate control efficiency.
Control efficiency is converted into probability value (y), and liquor strength (μ g/ml) converts logarithm value to (x), calculates virulence equation and concentration EC in suppressing with method of least squares
50, toxicity index and the co-toxicity coefficient (CTC) of medicament is calculated according to the abundant method of Sun Yun.
When CTC≤80, then composition shows as antagonism, and as 80 < CTC < 120, then composition shows as summation action, and when CTC >=120, then composition shows as synergistic effect.
Actual measurement toxicity index (ATI)=(standard agent EC
50/ reagent agent EC
50) × 100
In theoretical toxicity index (TTI)=A medicament toxicity index × mixture A percentage composition+B medicament toxicity index × mixture in the percentage composition of B
Co-toxicity coefficient (CTC)=[the theoretical toxicity index (TTI) of mixture actual measurement toxicity index (ATI)/mixture] × 100
Toxicity test result (table 1) shows, when the proportioning of malicious fluorine phosphorus and Enestroburin is between 40:1 ~ 1:40, have obvious synergistic effect to Pyricularia oryzae, time especially between 20:1 ~ 1:20, co-toxicity coefficient is more than 150.
Table 1 malicious fluorine phosphorus and the composite Toxicity Determination result to rice blast fungus of Enestroburin
| Process | EC 50（μg/ml） | ATI | TTI | CTC |
| Poison fluorine phosphorus | 23.67 | 100.00 | — | — |
| Enestroburin | 0.062 | 38177.42 | — | — |
| Poison fluorine phosphorus 40: Enestroburin 1 | 0.83 | 2849.82 | 2309.42 | 123.4 |
| Poison fluorine phosphorus 30: Enestroburin 1 | 0.78 | 3037.66 | 2290.85 | 132.6 |
| Poison fluorine phosphorus 20: Enestroburin 1 | 0.71 | 3332.27 | 2254.58 | 147.8 |
| Poison fluorine phosphorus 10: Enestroburin 1 | 0.66 | 3575.11 | 2152.38 | 166.1 |
| Poison fluorine phosphorus 1: Enestroburin 1 | 1.06 | 2233.18 | 1186.60 | 188.2 |
| Poison fluorine phosphorus 1: Enestroburin 10 | 5.57 | 424.63 | 220.82 | 192.3 |
| Poison fluorine phosphorus 1: Enestroburin 20 | 11.25 | 210.43 | 118.62 | 177.4 |
| Poison fluorine phosphorus 1: Enestroburin 30 | 18.21 | 129.96 | 82.35 | 157.8 |
| Poison fluorine phosphorus 1: Enestroburin 40 | 26.66 | 88.78 | 63.78 | 139.2 |
| Poison fluorine phosphorus 1: orysastrobin 50 | 0.61 | 1280.69 | 1031.98 | 124.1 |
Biologicall test example 2: malicious fluorine phosphorus and the composite Toxicity Determination to tobacco virus of Enestroburin
Subjects: tobacco virus
Test method: indoor pot tobacco susceptible variety plant, to the 4-5 leaf phase, with the isopyknic viral juice frictional inoculation of medicament mixing of different ratio variable concentrations, often processes 3 strains, often to select good strains in the field for seed 3 leaves, repeat 4 times, 3-4 days " Invest, Then Investigate " withered spot numbers, calculate inhibiting rate, use EC
50be worth the toxicity index and the co-toxicity coefficient (CTC) that calculate medicament according to the abundant method of Sun Yun.
Toxicity test result (table 2) shows, when the proportioning of malicious fluorine phosphorus and Enestroburin is between 40:1 ~ 1:40, have obvious synergistic effect to tobacco virus, time especially between 20:1 ~ 1:20, co-toxicity coefficient is more than 150.
Table 2 malicious fluorine phosphorus and the composite Toxicity Determination result to tobacco virus of Enestroburin
| Process | EC 50（μg/ml） | ATI | TTI | CTC |
| Poison fluorine phosphorus | 7.81 | 100.00 | — | — |
| Enestroburin | 11.13 | 70.17 | — | — |
| Poison fluorine phosphorus 50: Enestroburin 1 | 0.82 | 957.61 | 787.51 | 121.6 |
| Poison fluorine phosphorus 40: Enestroburin 1 | 0.71 | 1094.48 | 789.10 | 138.7 |
| Poison fluorine phosphorus 30: Enestroburin 1 | 0.66 | 1191.52 | 791.71 | 150.5 |
| Poison fluorine phosphorus 20: Enestroburin 1 | 0.58 | 1349.00 | 796.81 | 169.3 |
| Poison fluorine phosphorus 10: Enestroburin 1 | 0.52 | 1509.61 | 811.18 | 186.1 |
| Poison fluorine phosphorus 1: Enestroburin 1 | 0.46 | 1693.24 | 947.00 | 178.8 |
| Poison fluorine phosphorus 1: Enestroburin 10 | 0.45 | 1745.50 | 1082.82 | 161.2 |
| Poison fluorine phosphorus 1: Enestroburin 20 | 0.47 | 1668.83 | 1097.19 | 152.1 |
| Poison fluorine phosphorus 1: Enestroburin 30 | 0.51 | 1546.51 | 1102.29 | 140.3 |
| Poison fluorine phosphorus 1: Enestroburin 40 | 0.55 | 1424.22 | 1104.90 | 128.9 |
Fungicidal composition of the present invention can be prepared into any one formulation of applicable agricultural use by known method, reasonable formulation is wetting powder, suspending agent, water dispersible granules.
In order to make object of the present invention, technical scheme and advantage clearly understand, the following specific embodiment of the present invention is described, but the present invention is limited to absolutely not these examples.The following stated is only the good embodiment of the present invention, only in order to explain the present invention, therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.In all formulas, percentage is all weight percentage.The processing technology of each preparation of the present composition is prior art, can change to some extent according to different situations.
Embodiment 1:5% poison Fu Lin ﹒ orysastrobin suspending agent
A component such as active component, dispersant, thickener, wetting agent, antifreeze and water is mixed in the ratio of formula, after high speed shear, obtains 5% malicious Fu Lin ﹒ orysastrobin suspending agent.
This embodiment is applied to control rice blast.5% malicious Fu Lin ﹒ orysastrobin suspending agent is according to the spraying of 300g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 88.6%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 20% orysastrobin wetting powder is according to 300g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 73.2% and 81.9%.Poison fluorine phosphorus and the composite rear synergistic effect of orysastrobin obviously, to the control efficiency of rice blast significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 2:21% poison Fu Lin ﹒ SYP-3375 suspending agent
A component such as active component, dispersant, thickener, wetting agent, antifreeze and water is mixed in the ratio of formula, after high speed shear, obtains 21% malicious Fu Lin ﹒ SYP-3375 suspending agent.
This embodiment is applied to control rice blast.21% malicious Fu Lin ﹒ SYP-3375 suspending agent is according to the spraying of 300g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 87.2%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 20% SYP-3375 suspending agent is according to 300g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 73.2% and 79.5%.Poison fluorine phosphorus and the composite rear synergistic effect of SYP-3375 obviously, to the control efficiency of rice blast significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 3:42% poison Fu Lin ﹒ oxime bacterium ester wetting powder
Active component and various auxiliary agent and filler etc. are mixed in the ratio of formula, after ultra-fine pulverizer disintegrating, obtains 42% malicious Fu Lin ﹒ oxime bacterium ester wetting powder.
This embodiment is applied to control rice blast.42% malicious Fu Lin ﹒ oxime bacterium ester wetting powder is according to the spraying of 300g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 88.3%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 25% oxime bacterium ester suspending agent is according to 300g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 73.2% and 78.4%.Poison fluorine phosphorus and the composite rear synergistic effect of oxime bacterium ester obviously, to the control efficiency of rice blast significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 4:60% poison Fu Lin ﹒ Enestroburin wetting powder
Active component and various auxiliary agent and filler etc. are mixed in the ratio of formula, after ultra-fine pulverizer disintegrating, obtains 60% malicious Fu Lin ﹒ Enestroburin wetting powder.
This embodiment is applied to control rice blast.60% malicious Fu Lin ﹒ Enestroburin wetting powder is according to the spraying of 200g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 87.6%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 25% Enestroburin missible oil is according to 200g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 73.2% and 80.4%.Poison fluorine phosphorus and the composite rear synergistic effect of Enestroburin obviously, to the control efficiency of rice blast significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 5:51% poison Fu Lin ﹒ Orysastrobin water dispersible granule
Active component and various auxiliary agent and filler etc. are mixed in the ratio of formula, after air-flow crushing, obtains wetting powder, then add a certain amount of water mixing extruder grain, after drying screening, obtain 51% malicious Fu Lin ﹒ Orysastrobin water dispersible granule.
This embodiment is applied to control rice blast.51% malicious Fu Lin ﹒ Orysastrobin water dispersible granule.According to the spraying of 300g a.i/ha thin up, after medicine, the control efficiency of 10 days is 89.4%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i/ha, and 20% orysastrobin wetting powder is according to 300g a.i/ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 73.2% and 81.9%.Poison fluorine phosphorus and the composite rear synergistic effect of orysastrobin obviously, to the control efficiency of rice blast significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 6:75% poison Fu Lin ﹒ Enestroburin water dispersible granules
Active component and various auxiliary agent and filler etc. are mixed in the ratio of formula, after air-flow crushing, obtains wetting powder, then add a certain amount of water mixing extruder grain, after drying screening, obtain 75% malicious Fu Lin ﹒ Enestroburin water dispersible granules.
This embodiment is applied to control rice blast.75% malicious Fu Lin ﹒ Enestroburin water dispersible granules is according to the spraying of 200g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 87.9%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 25% Enestroburin missible oil is according to 200g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 73.2% and 80.4%.Poison fluorine phosphorus and the composite rear synergistic effect of Enestroburin obviously, to the control efficiency of rice blast significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 7:10% poison Fu Lin ﹒ oxime bacterium ester suspending agent
A component such as active component, dispersant, thickener, wetting agent, antifreeze and water is mixed in the ratio of formula, after high speed shear, obtains 10% malicious Fu Lin ﹒ oxime bacterium ester suspending agent.
This embodiment is applied to control tobacco virus.10% malicious Fu Lin ﹒ oxime bacterium ester suspending agent is according to the spraying of 300g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 81.3%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 25% oxime bacterium ester suspending agent is according to 300g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 78.6% and 66.4%.Poison fluorine phosphorus and the composite rear synergistic effect of oxime bacterium ester obviously, to the control efficiency of tobacco virus significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 8:15% poison Fu Lin ﹒ Enestroburin suspending agent
A component such as active component, dispersant, thickener, wetting agent, antifreeze and water is mixed in the ratio of formula, after high speed shear, obtains 15% malicious Fu Lin ﹒ Enestroburin suspending agent.
This embodiment is applied to control tobacco virus.15% malicious Fu Lin ﹒ Enestroburin suspending agent is according to the spraying of 200g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 81.7%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 25% Enestroburin missible oil is according to 200g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 78.6% and 63.9%.Poison fluorine phosphorus and the composite rear synergistic effect of Enestroburin obviously, to the control efficiency of tobacco virus significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 9:30% poison Fu Lin ﹒ orysastrobin wetting powder
Active component and various auxiliary agent and filler etc. are mixed in the ratio of formula, after ultra-fine pulverizer disintegrating, obtain 30% malicious fluorine phosphorus ﹒ orysastrobin wetting powder.
This embodiment is applied to control tobacco virus.30% malicious Fu Lin ﹒ orysastrobin wetting powder is according to the spraying of 300g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 84.1%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 20% orysastrobin wetting powder is according to 300g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 78.6% and 63.7%.Poison fluorine phosphorus and the composite rear synergistic effect of orysastrobin obviously, to the control efficiency of tobacco virus significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 10:80% poison Fu Lin ﹒ SYP-3375 wetting powder
Active component and various auxiliary agent and filler etc. are mixed in the ratio of formula, after ultra-fine pulverizer disintegrating, obtain 80% malicious fluorine phosphorus ﹒ SYP-3375 wetting powder.
This embodiment is applied to control tobacco virus.80% malicious Fu Lin ﹒ SYP-3375 wetting powder is according to the spraying of 300g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 84.8%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 20% SYP-3375 suspending agent is according to 300g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 78.6% and 62.5%.Poison fluorine phosphorus and the composite rear synergistic effect of SYP-3375 obviously, to the control efficiency of tobacco virus significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 11:51% poison Fu Lin ﹒ trifloxystrobin water dispersible granule
Active component and various auxiliary agent and filler etc. are mixed in the ratio of formula, after air-flow crushing, obtains wetting powder, then add a certain amount of water mixing extruder grain, after drying screening, obtain 51% malicious Fu Lin ﹒ trifloxystrobin water dispersible granule.
This embodiment is applied to control tobacco virus.51% malicious Fu Lin ﹒ trifloxystrobin water dispersible granule is according to the spraying of 300g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 83.6%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 25% oxime bacterium ester suspending agent is according to 300g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 78.6% and 66.4%.Poison fluorine phosphorus and the composite rear synergistic effect of oxime bacterium ester obviously, to the control efficiency of tobacco virus significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 12:65% poison Fu Lin ﹒ SYP-3375 water dispersible granules
Active component and various auxiliary agent and filler etc. are mixed in the ratio of formula, after air-flow crushing, obtains wetting powder, then add a certain amount of water mixing extruder grain, after drying screening, obtain 65% malicious Fu Lin ﹒ SYP-3375 water dispersible granules.
This embodiment is applied to control tobacco virus.65% malicious Fu Lin ﹒ SYP-3375 water dispersible granules is according to the spraying of 300g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 81.9%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 20% SYP-3375 suspending agent is according to 300g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 78.6% and 62.5%.Poison fluorine phosphorus and the composite rear synergistic effect of SYP-3375 obviously, to the control efficiency of tobacco virus significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Embodiment 13:50% poison Fu Lin ﹒ Orysastrobin water dispersible granule
Active component and various auxiliary agent and filler etc. are mixed in the ratio of formula, after air-flow crushing, obtains wetting powder, then add a certain amount of water mixing extruder grain, after drying screening, obtain 50% malicious Fu Lin ﹒ Orysastrobin water dispersible granule.
This embodiment is applied to control tobacco virus.50% malicious Fu Lin ﹒ Orysastrobin water dispersible granule is according to the spraying of 300g a.i./ha thin up, and after medicine, the control efficiency of 10 days is 82.1%.30% malicious fluorine phosphorus wetting powder is according to 200g a.i./ha, and 20% SYP-3375 suspending agent is according to 300g a.i./ha, and thin up is sprayed, and after medicine, the control efficiency of 10 days is respectively 78.6% and 62.5%.Poison fluorine phosphorus and the composite rear synergistic effect of SYP-3375 obviously, to the control efficiency of tobacco virus significantly better than single dose; Because pharmacy effect improves, obviously reduce when the amount ratio of active ingredient is used alone in compound drug, thus also mitigate the pollution to environment.
Claims (6)
1. the bactericidal composition of toxic fluorine phosphorus and Enestroburin, is characterized in that: active ingredient is malicious fluorine phosphorus and Enestroburin is composite forms, and the weight ratio of malicious fluorine phosphorus and Enestroburin is 40: 1 ~ 1: 40.
2. the bactericidal composition of toxic fluorine phosphorus according to claim 1 and Enestroburin, is characterized in that: the weight ratio of described malicious fluorine phosphorus and Enestroburin is 20: 1 ~ 1: 20.
3. the bactericidal composition of toxic fluorine phosphorus according to claim 1 and 2 and Enestroburin, is characterized in that: described bactericidal composition is prepared into wetting powder, suspending agent, water dispersible granules.
4. the bactericidal composition of toxic fluorine phosphorus according to claim 3 and Enestroburin, it is characterized in that: the percentage by weight that the weight summation of described malicious fluorine phosphorus and Enestroburin accounts for bactericidal composition gross weight is 5 ~ 80%, and surplus is acceptable auxiliary element auxiliary agent on agricultural chemicals.
5. the bactericidal composition of toxic fluorine phosphorus according to claim 3 and Enestroburin, it is characterized in that: the percentage by weight that the weight summation of described malicious fluorine phosphorus and Enestroburin accounts for bactericidal composition gross weight is 10 ~ 60%, and surplus is acceptable auxiliary element auxiliary agent on agricultural chemicals.
6. the application of the toxic fluorine phosphorus as described in claim 4 or 5 and the bactericidal composition of Enestroburin, is characterized in that: it is preventing and treating the application in crop pest.
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