CN103599425A - Novel double-ant capsule for clearing dampness and dredging collaterals - Google Patents
Novel double-ant capsule for clearing dampness and dredging collaterals Download PDFInfo
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- CN103599425A CN103599425A CN201310551572.4A CN201310551572A CN103599425A CN 103599425 A CN103599425 A CN 103599425A CN 201310551572 A CN201310551572 A CN 201310551572A CN 103599425 A CN103599425 A CN 103599425A
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Abstract
The invention discloses a novel double-ant capsule for clearing dampness and dredging collaterals. The novel double-ant capsule comprises the following important raw materials: 10-20 parts of silky ant, 4-8 parts of odontotermes formosanus, 0.5-1.0 part of ginseng, 10-15 parts of astragalus membranaceus, 2-5 parts of bighead atractylodes rhizome, 5-10 parts of angelica sinensis, 1-5 parts of root of red-rooted salvia, 0.5-1 part of radix aconiti preparata, 2-6 parts of caulis spatholobi, 1-5 parts of morinda officinalis, 1-5 parts of herba epimedii, 0.5-1.0 part of radix achyranthis bidentatae, 10-15 parts of radix clematidis, 0.2-0.8 parts of centipede, 0.5-1.0 part of scorpion,1-5 parts of carthamus tinctorius linne, 6-12 parts of fruit of Chinese wolfberry, 1-3 parts of semen coicis, and 3-9 parts of honeysuckle. By adopting the honeysuckle added to the novel double-ant capsule, the effective components of the other 18 traditional Chinese medicines can be effectively extracted; the medicine properties can be furthest volatilized; the used medicinal materials can be fully utilized; furthermore, the effective components of each traditional Chinese medicine are furthest extracted, so that the quantity of the used medicinal materials is relatively reduced, the production cost is also reduced, and the productivity effect is improved.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of skeletal diseases, relate in particular to a kind of medicine for the treatment of rheumatism sexually transmitted disease (STD) class.
Background technology
Rheumatism and rheumatoid joint patient, and limb muscle or joint etc. convulsion pain is miserable, arthromyodynia patient's large contingents such as numb severe one, joint stuffiness and arthroncus.These threaten people's health disease seriously, bring inconvenience to people's live and work, and even life all can not be administered.But it is still rare to apply with the medicine of thoroughly treating these diseases, people's multiple medicines thing is to cure the symptoms, not the disease, during medication, take a turn for the better, and recurrence again after drug withdrawal.
Just > > record in < < journal Heavenly Palace > > and < < Book of Rites when China's summer, business, week, emperor, except offering a sacrifice to gods or ancestors, fetes to enjoy also and will eat ant beans; Note has in Ming Dynasty physician Li Shizhen (1518-1593 A.D.) < < Compendium of Materia Medica > >: ant, and also name Formica fusca, its Luan Ming Qi, recluse dig it, and ancients eat it.Add, ancient times, the chief of a tribe was beans mainly with ant, and non-honorable non-availability also.Also describe: Coptotermes formosanus Shtrari. mud, cure mainly malignant boil toxic swelling, with person on Masson Pine, with Plumbum preparatium, iron and fry blackly, grind and Oleum sesami, get more it.
There are the social mores of edible Odontotermes formosanus Shiraki three Shi Nianqian， Philippine some areas, have people that black ant, Coptotermes formosanus Shtrari. are classified as to top grade in food in Africa, India, Australia.It is at present domestic that to take preparation and production unit that black ant, Coptotermes formosanus Shtrari. be primary raw material less, and commercially available Formica fusca processed goods only rests on Formica fusca is dried and clays into power or make Formica fusca powder capsule or traditional Ants Wine at present, as: " the floating wine of god ", " consoling the nectar " they are all that employing Formica fusca, black wing Coptotermes formosanus Shtrari. are that raw material is made, these formula for a product are simple, and function is limited.The method that production technology is just soaked by traditional wine is obtained the effective ingredient of Formica fusca, black wing hargil ant.Because the effective active comparison of ingredients of Formica fusca, Odontotermes formosanus Shiraki is many, traditional immersion process cannot all obtain effective ingredient, and takes some people in crowd and easily produce anaphylaxis.On the other hand, above two kinds of medicated wine all belong to healthcare food, take the course for the treatment of longer, and curative effect is not obvious, takes medicated wine and also by quite a few crowd, is avoided.
Patent No. CN1557383A discloses a kind of dual-ant wet-dispelling and collateral-dredging capsule, and it has comprised Formica fusca and Odontotermes formosanus Shiraki and 18 taste Chinese medicines and has made.This invention can larger limit be extracted the effective ingredient in Formica fusca, Odontotermes formosanus Shiraki, be equipped with 18 taste Chinese medicines, make made medicine there is invigorating the liver and kidney, replenishing QI and blood, promoting blood circulation to remove obstruction in the collateral, the effect of expelling wind and removing dampness, can significantly improve both liver and kidney deficiency, the arthromyodynia symptoms such as the chills and pain of the waist and kness that insufficiency of vital energy and blood causes, podomere swelling, can effectively treat rheumatic arthritis, rheumatoid arthritis, sciatica, osteoproliferation disease field curative effect are more remarkable than other drug, and safe and reliable, without any side effects.But the drug effect of this formula also fails to bring into play to greatest extent, and medicine can not be fully utilized.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, invent a kind of novel dual-ant wet-dispelling and collateral-dredging capsule, can improve to greatest extent drug effect, treatment rheumatic class is ailing.
For realizing foregoing invention, main contents of the present invention are:
The present invention comprises following important umber raw material: 10～20 parts of Formica fuscas, 4～8 parts of Odontotermes formosanus Shiraki, 0.5～1.0 part of Radix Ginseng, 10～15 parts of the Radixs Astragali, 2～5 parts of the Rhizoma Atractylodis Macrocephalaes, 5～10 parts of Radix Angelicae Sinensis, 1～5 part of Radix Salviae Miltiorrhizae, 0.5～1 part of Radix Aconiti Preparata, 2～6 parts of Caulis Spatholobis, 1～5 part of Radix Morindae Officinalis, 1～5 part of Herba Epimedii, 0.5～1.0 part of Radix Achyranthis Bidentatae, 10～15 parts of Radix Clematidis, 0.2～0.8 part of Scolopendra, 0.5～1.0 part of Scorpio, 1～5 part, Flos Carthami, 6～12 parts of Fructus Lycii, 1～3 part of Semen Coicis, 3～9 parts of Flos Loniceraes.
Preferably, comprise following important umber raw material: 15～18 parts of Formica fuscas, 5～7 parts of Odontotermes formosanus Shiraki, 0.6～1.0 part of Radix Ginseng, 12～14 parts of the Radixs Astragali, 2～4 parts of the Rhizoma Atractylodis Macrocephalaes, 6～9 parts of Radix Angelicae Sinensis, 2～4 parts of Radix Salviae Miltiorrhizaes, 0.5～0.8 part of Radix Aconiti Preparata, 3～5 parts of Caulis Spatholobis, 2～4 parts of Radix Morindae Officinaliss, 3～5 parts of Herba Epimedii, 0.5～0.9 part of Radix Achyranthis Bidentatae, 10～15 parts of Radix Clematidis, 0.2～0.5 part of Scolopendra, 0.6～1.0 part of Scorpio, 1～3 part, Flos Carthami, 7～10 parts of Fructus Lycii, 1～3 part of Semen Coicis, 3～7 parts of Flos Loniceraes.
A novel dual-ant wet-dispelling and collateral-dredging capsule, comprises following operating procedure:
(1) by each umber, got raw material;
(2) Radix Ginseng, Radix Clematidis are ground into powder, cross 80～120 mesh sieves;
(3) Formica fusca, Odontotermes formosanus Shiraki, Scorpio, Scolopendra, Flos Lonicerae powder are broken into powder, cross 10～50 mesh sieves;
(4) medical material of handling well in step (3) is added to 45～65% ethanol and carry out reflux, extract,, concentrating under reduced pressure extracting solution, filters;
(5) 12 tastes such as the remaining Radix Astragali are added and are decocted in water for oral dose, filter, concentrated filtrate becomes clear paste, adds ethanol and makes clear paste contain alcohol amount to reach 60%, stir evenly standing 24 hours;
(6) supernatant and the filtrate in step (4) of getting in step (5) merge, and are condensed into thick paste, add gained powder in step (2), mix;
(7) gained medicine in step (6) is made to capsule.
Preferably, in step (4), add respectively the amount of 5 times, 4 times, 3 times that 45～65% ethanol and amount are step (4) Chinese crude drug umber 75～85 ℃ of reflux, extract, three times, extract 1～2 hour at every turn.
Preferably, the water yield of 8 times, 7 times that adds respectively step (5) Chinese crude drug umber in step (5) decocts twice, decocts 1～2 hour at every turn.
Preferably, in step (5) in the time of 65～75 ℃ filtrate to be concentrated into relative density be 1.0～1.3 clear paste.
Preferably, in step (6) in the time of 65～75 ℃ filtrate to be concentrated into relative density be 1.0～1.5 thick paste.
Compared with prior art, beneficial effect of the present invention:
The present invention has invigorating the liver and kidney, replenishing QI and blood, promoting blood circulation to remove obstruction in the collateral, and the effect of expelling wind and removing dampness, can significantly improve the arthromyodynia symptoms such as both liver and kidney deficiency, the chills and pain of the waist and kness that insufficiency of vital energy and blood causes, podomere swelling, can effectively treat rheumatic arthritis, rheumatoid arthritis; The Flos Lonicerae simply that importantly the present invention adds, can effectively adsorb, concentrate the effective ingredient in other 18 taste Chinese medicines, makes to greatest extent the property of medicine evaporate, and medicine used can be fully utilized; Further, in each, the effective elements of the medicine has been extracted to greatest extent, and medical material amount used is reduced relatively, has reduced production cost, has improved productivity effect.
The specific embodiment
Referring to the specific embodiment, further describe the present invention, to make those skilled in the art can implement according to this with reference to description word, protection domain of the present invention is not limited by embodiments of the present invention.
Embodiment 1
By 30 parts of 100 parts of Formica fuscas, 40 parts of Odontotermes formosanus Shiraki, 5 parts of Radix Ginsengs, 100 parts of the Radixs Astragali, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 50 parts of Radix Angelicae Sinensis, 10 parts of Radix Salviae Miltiorrhizaes, 5 parts of Radix Aconiti Preparatas, 20 parts of Caulis Spatholobis, 10 parts of Radix Morindae Officinaliss, 10 parts of Herba Epimedii, 5 parts of Radix Achyranthis Bidentataes, 100 parts of Radix Clematidis, 2 parts of Scolopendras, 5 parts of Scorpios, 10 parts, Flos Carthami, 60 parts of Fructus Lycii, 10 parts of Semen Coiciss, Flos Lonicerae, got raw material; Then by Formica fusca, Odontotermes formosanus Shiraki, Radix Ginseng, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Aconiti Preparata, Caulis Spatholobi, Radix Morindae Officinalis, Herba Epimedii, Radix Achyranthis Bidentatae, Radix Clematidis, Scolopendra, Scorpio, Flos Carthami, Fructus Lycii, Semen Coicis, Flos Lonicerae 19 taste Chinese medicine chip selects, remove impurity, before feeding intake, clean; After wherein Radix Ginseng, Radix Clematidis are cleaned, in 60 ℃ of oven dry, be ground into respectively powder, cross 80 mesh sieves, gained powder is in 100 ℃ of high pressure moist heat sterilizations 60 minutes, and 85 ℃ of oven dry are standby; Then Formica fusca, Odontotermes formosanus Shiraki, Scorpio, Scolopendra, Flos Lonicerae powder are broken into powder, cross 10 mesh sieves; The amount of 5 times, 4 times, 3 times that to add 45% ethanol and amount be Formica fusca, Odontotermes formosanus Shiraki, Scorpio, Scolopendra, Flos Lonicerae powder, 75 ℃ of reflux, extract, three times, is extracted 1 hour at every turn, and merge extractive liquid, is standing, filters green filtrate for later use; The remaining Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Aconiti Preparata, Caulis Spatholobi, Radix Morindae Officinalis, Herba Epimedii, Radix Achyranthis Bidentatae, Flos Carthami, Fructus Lycii, Semen Coicis 12 tastes are added to the water yield that water adds respectively 8 times, 7 times of 12 taste Chinese crude drug umbers to be decocted twice, each decoction 1 hour, filter, in the time of 65 ℃ filtrate to be concentrated into relative density be 1.0 clear paste, adding ethanol makes clear paste contain alcohol amount to reach 60%, stir evenly standing 24 hours; The filtrate of the Chinese medicine of the five flavours such as the supernatant of 12 taste Chinese medicines and Formica fusca is merged, and to be condensed into relative density be 1.0 thick paste, add Radix Ginseng, Radix Clematidis powder, mix and add above-mentioned thick paste mix homogeneously, granulation, in 80 ℃ of oven dry, pulverizes, cross 100 mesh sieves, obtain medicated powder and add appropriate magnesium stearate and sterilized starch, mix, in incapsulating, every dress 0.4g, is product.
Embodiment 2
By 60 parts of 200 parts of Formica fuscas, 50 parts of Odontotermes formosanus Shiraki, 7 parts of Radix Ginsengs, 125 parts of the Radixs Astragali, 25 parts of the Rhizoma Atractylodis Macrocephalaes, 75 parts of Radix Angelicae Sinensis, 25 parts of Radix Salviae Miltiorrhizaes, 6 parts of Radix Aconiti Preparatas, 40 parts of Caulis Spatholobis, 25 parts of Radix Morindae Officinaliss, 30 parts of Herba Epimedii, 7 parts of Radix Achyranthis Bidentataes, 125 parts of Radix Clematidis, 5 parts of Scolopendras, 7 parts of Scorpios, 25 parts, Flos Carthami, 90 parts of Fructus Lycii, 20 parts of Semen Coiciss, Flos Lonicerae, got raw material; Then by Formica fusca, Odontotermes formosanus Shiraki, Radix Ginseng, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Aconiti Preparata, Caulis Spatholobi, Radix Morindae Officinalis, Herba Epimedii, Radix Achyranthis Bidentatae, Radix Clematidis, Scolopendra, Scorpio, Flos Carthami, Fructus Lycii, Semen Coicis, Flos Lonicerae 19 taste Chinese medicine chip selects, remove impurity, before feeding intake, clean; After wherein Radix Ginseng, Radix Clematidis are cleaned, in 60 ℃ of oven dry, be ground into respectively powder, cross 100 mesh sieves, gained powder is in 100 ℃ of high pressure moist heat sterilizations 60 minutes, and 85 ℃ of oven dry are standby; Then Formica fusca, Odontotermes formosanus Shiraki, Scorpio, Scolopendra, Flos Lonicerae powder are broken into powder, cross 24 mesh sieves; The amount of 5 times, 4 times, 3 times that to add 60% ethanol and amount be Formica fusca, Odontotermes formosanus Shiraki, Scorpio, Scolopendra, Flos Lonicerae powder, 80 ℃ of reflux, extract, three times, is extracted 1 hour at every turn, and merge extractive liquid, is standing, filters green filtrate for later use; The remaining Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Aconiti Preparata, Caulis Spatholobi, Radix Morindae Officinalis, Herba Epimedii, Radix Achyranthis Bidentatae, Flos Carthami, Fructus Lycii, Semen Coicis 12 tastes are added to the water yield that water adds respectively 8 times, 7 times of 12 taste Chinese crude drug umbers to be decocted twice, each decoction 1 hour, filter, in the time of 65 ℃ filtrate to be concentrated into relative density be 1.2 clear paste, adding ethanol makes clear paste contain alcohol amount to reach 60%, stir evenly standing 24 hours; The filtrate of the Chinese medicine of the five flavours such as the supernatant of 12 taste Chinese medicines and Formica fusca is merged, and to be condensed into relative density be 1.2 thick paste, add Radix Ginseng, Radix Clematidis powder, mix and add above-mentioned thick paste mix homogeneously, granulation, in 80 ℃ of oven dry, pulverizes, cross 100 mesh sieves, obtain medicated powder and add appropriate magnesium stearate and sterilized starch, mix, in incapsulating, every dress 0.4g, is product.
Embodiment 3
By 90 parts of 150 parts of Formica fuscas, 80 parts of Odontotermes formosanus Shiraki, 10 parts of Radix Ginsengs, 150 parts of the Radixs Astragali, 50 parts of the Rhizoma Atractylodis Macrocephalaes, 100 parts of Radix Angelicae Sinensis, 50 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Aconiti Preparatas, 60 parts of Caulis Spatholobis, 50 parts of Radix Morindae Officinaliss, 50 parts of Herba Epimedii, 10 parts of Radix Achyranthis Bidentataes, 150 parts of Radix Clematidis, 8 parts of Scolopendras, 10 parts of Scorpios, 50 parts, Flos Carthami, 120 parts of Fructus Lycii, 30 parts of Semen Coiciss, Flos Lonicerae, got raw material; Then by Formica fusca, Odontotermes formosanus Shiraki, Radix Ginseng, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Aconiti Preparata, Caulis Spatholobi, Radix Morindae Officinalis, Herba Epimedii, Radix Achyranthis Bidentatae, Radix Clematidis, Scolopendra, Scorpio, Flos Carthami, Fructus Lycii, Semen Coicis, Flos Lonicerae 19 taste Chinese medicine chip selects, remove impurity, before feeding intake, clean; After wherein Radix Ginseng, Radix Clematidis are cleaned, in 60 ℃ of oven dry, be ground into respectively powder, cross 120 mesh sieves, gained powder is in 100 ℃ of high pressure moist heat sterilizations 60 minutes, and 85 ℃ of oven dry are standby; Then Formica fusca, Odontotermes formosanus Shiraki, Scorpio, Scolopendra, Flos Lonicerae powder are broken into powder, cross 50 mesh sieves; The amount of 5 times, 4 times, 3 times that to add 65% ethanol and amount be Formica fusca, Odontotermes formosanus Shiraki, Scorpio, Scolopendra, Flos Lonicerae powder, 80 ℃ of reflux, extract, three times, is extracted 1 hour at every turn, and merge extractive liquid, is standing, filters green filtrate for later use; The remaining Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Aconiti Preparata, Caulis Spatholobi, Radix Morindae Officinalis, Herba Epimedii, Radix Achyranthis Bidentatae, Flos Carthami, Fructus Lycii, Semen Coicis 12 tastes are added to the water yield that water adds respectively 8 times, 7 times of 12 taste Chinese crude drug umbers to be decocted twice, each decoction 1 hour, filter, in the time of 65 ℃ filtrate to be concentrated into relative density be 1.3 clear paste, adding ethanol makes clear paste contain alcohol amount to reach 60%, stir evenly standing 24 hours; The filtrate of the Chinese medicine of the five flavours such as the supernatant of 12 taste Chinese medicines and Formica fusca is merged, and to be condensed into relative density be 1.5 thick paste, add Radix Ginseng, Radix Clematidis powder, mix and add above-mentioned thick paste mix homogeneously, granulation, in 80 ℃ of oven dry, pulverizes, cross 100 mesh sieves, obtain medicated powder and add appropriate magnesium stearate and sterilized starch, mix, in incapsulating, every dress 0.4g, is product.
Typical case with capsule for treating of the present invention:
Example 1: Lee, female, 42 years old, the little arthralgia of main cause discontinuity whole body 3 years was in admission examination on November 1st, 2007, clinical symptoms: double knee joint swells and ache, joint stuffiness, left side is the most serious, bilateral carpal joint, elbow joint, metatarsophalangeal joints, metacarpophalangeal joints swelling, pain, limitation of activity, deformity, elbow joint local subcutaneous tuberosity, skin color is normal.Auxiliary examination: routine blood test shows: HB80g/L (hemoglobinometry), RF (+) (rheumatoid factor), ESR142mm/h (erythrocyte sedimentation rate).Tired mind, the both hands palms refers to, metatarsophalangeal joints deformity, double knee joint, carpal joint, exercising elbow joint are limited, two percussion tenderness over kidney region, two lower limb concavity edema II degree, dimly red tongue, tongue is white, and deep-thready pulse is puckery.Take the capsule of making in above-described embodiment 1, every day 3 times, take medicine after 2 weeks before disease improvement relax, 3 weeks posterior joints all diseases disappearance of swelling and ache.Reinspection routine blood test is normal, HB:101g/L, (hemoglobinometry), and RF (-) (rheumatoid factor), ESR:40mm/h (erythrocyte sedimentation rate), reaches healing object.Follow up a case by regular visits to 1 year, the state of an illness does not recur.
Example 2: blue certain, female, 38 years old.Main suit: extremities joint swells and ache more than 5 years, increases the weight of more than March.In March, 2008, be admitted to hospital, clinical disease: the right hand the 3rd joint, left knee joint, left ankle joint swell and ache, joint stuffiness, companion's deadlock in morning 2 hours, tenderness, local scorching hot, two hip pain, is diagnosed as rheumatoid arthritis.Auxiliary examination: routine blood test shows, HB80g/L (hemoglobinometry), remaining normal, RF (+) (rheumatoid factor), ESR142mm/h (erythrocyte sedimentation rate).X-ray film shows: both hands osteoporosis, and the part palm refers to, nearly articulations digitorum manus is narrow, fuzzy, folliculus sample becomes, soft tissue of joint swelling, two wrist soft tissue swellings, gap turn narrow, double knee joint soft tissue swelling, joint space narrows down, osteoporosis, joint margins hyperosteogeny forms.Take the capsule of making in above-described embodiment 2, every day 3 times, each 4, take medicine after 2 weeks before disease improvement relax, 3 weeks posterior joints all diseases disappearance of swelling and ache, can ownly walk.Look into Hb:101g/L, (hemoglobinometry), ESR:40mm/h (erythrocyte sedimentation rate), each arthralgia disappears, movable convenient, the life of can taking care of oneself.Except walking slightly slowly, basic as ordinary person.Follow up a case by regular visits to 1 year, the state of an illness does not recur, and can be in and do simple farm work.
Example 3: Zhang, man, 55 years old, main suit: opening glass cap has certain difficulty with the clothing button of buckling oneself, but can dry the health of oneself and ceaselessly walk 300 meters after shower, and sufferer can be the carpenter of 12 hours weekly reluctantly, but due to arthralgia, gradually feel not competent its work.In February, 2009, be admitted to hospital, clinical disease: symmetry multi-joint pain and swelling 5 years.The joint of getting involved comprises that the bilateral palm refers to, near-end refer between, wrist, elbow, knee joint and metatarsophalangeal joints, arthralgia is 4/10, and has deadlock in one hour morning.Take the capsule of making in above-described embodiment 3, every day 3 times, each 4, take medicine after 1 week before disease improvement relax, 2 weeks posterior joints all diseases disappearance of swelling and ache.Check: RF positive (102U/ml), IFANA are negative, ESR15mm/ hour, platelet 254000/ul, liver function are normal, normal renal function, euthyroidism, anti-hepatitis B and c-hepatitis antibody is negative, serum protein electrophoresis is normal.X-ray examination does not find that the bone of any typical rheumatoid arthritis damages.
The present invention has invigorating the liver and kidney, replenishing QI and blood, promoting blood circulation to remove obstruction in the collateral, and the effect of expelling wind and removing dampness, can significantly improve the arthromyodynia symptoms such as both liver and kidney deficiency, the chills and pain of the waist and kness that insufficiency of vital energy and blood causes, podomere swelling, can effectively treat rheumatic arthritis, rheumatoid arthritis; The Flos Lonicerae simply that importantly the present invention adds, can effectively adsorb, concentrate the effective ingredient in other 18 taste Chinese medicines, makes to greatest extent the property of medicine evaporate, and medicine used can be fully utilized; Further, in each, the effective elements of the medicine has been extracted to greatest extent, and medical material amount used is reduced relatively, has reduced production cost, has improved productivity effect.
Claims (7)
1. a novel dual-ant wet-dispelling and collateral-dredging capsule, it is characterized in that, comprise following important umber raw material: 10～20 parts of Formica fuscas, 4～8 parts of Odontotermes formosanus Shiraki, 0.5～1.0 part of Radix Ginseng, 10～15 parts of the Radixs Astragali, 2～5 parts of the Rhizoma Atractylodis Macrocephalaes, 5～10 parts of Radix Angelicae Sinensis, 1～5 part of Radix Salviae Miltiorrhizae, 0.5～1 part of Radix Aconiti Preparata, 2～6 parts of Caulis Spatholobis, 1～5 part of Radix Morindae Officinalis, 1～5 part of Herba Epimedii, 0.5～1.0 part of Radix Achyranthis Bidentatae, 10～15 parts of Radix Clematidis, 0.2～0.8 part of Scolopendra, 0.5～1.0 part of Scorpio, 1～5 part, Flos Carthami, 6～12 parts of Fructus Lycii, 1～3 part of Semen Coicis, 3～9 parts of Flos Loniceraes.
2. novel dual-ant wet-dispelling and collateral-dredging capsule according to claim 1, it is characterized in that, comprise following important umber raw material: 15～18 parts of Formica fuscas, 5～7 parts of Odontotermes formosanus Shiraki, 0.6～1.0 part of Radix Ginseng, 12～14 parts of the Radixs Astragali, 2～4 parts of the Rhizoma Atractylodis Macrocephalaes, 6～9 parts of Radix Angelicae Sinensis, 2～4 parts of Radix Salviae Miltiorrhizaes, 0.5～0.8 part of Radix Aconiti Preparata, 3～5 parts of Caulis Spatholobis, 2～4 parts of Radix Morindae Officinaliss, 3～5 parts of Herba Epimedii, 0.5～0.9 part of Radix Achyranthis Bidentatae, 10～15 parts of Radix Clematidis, 0.2～0.5 part of Scolopendra, 0.6～1.0 part of Scorpio, 1～3 part, Flos Carthami, 7～10 parts of Fructus Lycii, 1～3 part of Semen Coicis, 3～7 parts of Flos Loniceraes.
3. a production method for novel dual-ant wet-dispelling and collateral-dredging capsule described in claim 2, is characterized in that, comprises following operating procedure:
(1) by each umber, got raw material;
(2) Radix Ginseng, Radix Clematidis are ground into powder, cross 80～120 mesh sieves;
(3) Formica fusca, Odontotermes formosanus Shiraki, Scorpio, Scolopendra, Flos Lonicerae powder are broken into powder, cross 10～50 mesh sieves;
(4) medical material of handling well in step (3) is added to 45～65% ethanol and carry out reflux, extract,, concentrating under reduced pressure extracting solution, filters;
(5) 12 tastes such as the remaining Radix Astragali are added and are decocted in water for oral dose, filter, concentrated filtrate becomes clear paste, adds ethanol and makes clear paste contain alcohol amount to reach 60%, stir evenly standing 24 hours;
(6) supernatant and the filtrate in step (4) of getting in step (5) merge, and are condensed into thick paste, add gained powder in step (2), mix;
(7) gained medicine in step (6) is made to capsule.
4. novel dual-ant wet-dispelling and collateral-dredging capsule according to claim 3, it is characterized in that: in step (4), add respectively the amount of 5 times, 4 times, 3 times that 45～65% ethanol and amount are step (4) Chinese crude drug umber 75～85 ℃ of reflux, extract, three times, extract 1～2 hour at every turn.
5. novel dual-ant wet-dispelling and collateral-dredging capsule according to claim 3, is characterized in that: the water yield of 8 times, 7 times that adds respectively step (5) Chinese crude drug umber in step (5) decocts twice, decocts 1～2 hour at every turn.
6. novel dual-ant wet-dispelling and collateral-dredging capsule according to claim 2, is characterized in that: in step (5) in the time of 65～75 ℃ filtrate to be concentrated into relative density be 1.0～1.3 clear paste.
7. novel dual-ant wet-dispelling and collateral-dredging capsule according to claim 2, is characterized in that: in step (6) in the time of 65～75 ℃ filtrate to be concentrated into relative density be 1.0～1.5 thick paste.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310551572.4A CN103599425A (en) | 2013-11-08 | 2013-11-08 | Novel double-ant capsule for clearing dampness and dredging collaterals |
Applications Claiming Priority (1)
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104147340A (en) * | 2014-08-28 | 2014-11-19 | 广西梧州三鹤药业有限公司 | Traditional Chinese medicine composition for treating rheumatic arthritis and rheumatoid arthritis |
| CN104667044A (en) * | 2015-02-15 | 2015-06-03 | 广西双蚁药业有限公司 | Traditional Chinese medicine preparation for treating arthralgia and preparation method of traditional Chinese medicine preparation |
| CN104984162A (en) * | 2015-06-30 | 2015-10-21 | 天峨县平昌生态农业有限公司 | Traditional Chinese medicine preparation with effects of dampness dispelling and collateral dredging |
| CN105031407A (en) * | 2015-08-27 | 2015-11-11 | 北京新世纪达康生物科技开发有限责任公司 | Traditional Chinese medicine formula for treating rheumatism and rheumatoid, preparation method and application of traditional Chinese medicine formula |
| CN105853499A (en) * | 2016-05-06 | 2016-08-17 | 方桂兰 | Ostealgia and arthritis treatment drug for external use, preparation method thereof and ointment for external use |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147340A (en) * | 2014-08-28 | 2014-11-19 | 广西梧州三鹤药业有限公司 | Traditional Chinese medicine composition for treating rheumatic arthritis and rheumatoid arthritis |
| CN104147340B (en) * | 2014-08-28 | 2017-10-20 | 广西梧州三鹤药业有限公司 | Treat rheumatism, the Chinese medicine composition of rheumatoid arthritis |
| CN104667044A (en) * | 2015-02-15 | 2015-06-03 | 广西双蚁药业有限公司 | Traditional Chinese medicine preparation for treating arthralgia and preparation method of traditional Chinese medicine preparation |
| CN104984162A (en) * | 2015-06-30 | 2015-10-21 | 天峨县平昌生态农业有限公司 | Traditional Chinese medicine preparation with effects of dampness dispelling and collateral dredging |
| CN105031407A (en) * | 2015-08-27 | 2015-11-11 | 北京新世纪达康生物科技开发有限责任公司 | Traditional Chinese medicine formula for treating rheumatism and rheumatoid, preparation method and application of traditional Chinese medicine formula |
| CN105031407B (en) * | 2015-08-27 | 2018-12-25 | 北京新世纪达康生物科技开发有限责任公司 | It is a kind of to treat rheumatism, the Chinese medicine composition of rheumatoid, preparation method and application |
| CN105853499A (en) * | 2016-05-06 | 2016-08-17 | 方桂兰 | Ostealgia and arthritis treatment drug for external use, preparation method thereof and ointment for external use |
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Application publication date: 20140226 |