CN103599231B - 防治伤口感染的中药药液及其制备方法 - Google Patents
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Abstract
本发明公开了一种防治伤口感染的中药药液及其制备方法,它是由以下重量份数的原料制成的:白花菜15-20份,一点红10-15份,虎杖10-15份、黄柏10-15份、穿心莲10-15份,制备方法是:将白花菜、一点红、虎杖、黄柏、穿心莲粉碎,用总重量3-5倍清水水煮沸20-30分钟,过滤,滤渣加1-2倍的清水,再煮沸10-15分钟,合并两次滤液,装瓶,无菌消毒。使用方法:直接涂抹于患处。本发明采用纯中药制成,无毒副作用,无耐药性,原材料来源广,生产成本低廉,制备过程简单,省时省力,使用方便。
Description
技术领域
本发明涉及一种防治伤口感染的中药药液及其制备方法。
背景技术
伤口感染指的是:创伤造成各种不同形式的伤口,如裂伤、割伤、刺伤、盲管伤、穿通伤等,致病菌或条件致病菌侵入血循环中生长繁殖,产生毒素和其他代谢产物所引起的反应,急性全身性感染会引起不同类型的感染,其感染的程度与伤口的大小、深浅、污染程度等密切相关。轻度感染的伤口仅出现红、肿、热、痛的局部症状。感染较严重者除伤口出现明显的局部症状外,还会出现高热、昏迷等全身性中毒症状。
严重时有可能演变成感染性休克,甚至导致死亡。
近年来,抗菌药物滥用,细菌耐药性问题凸显,逐步发展成为影响治疗感染性疾病的治疗的抗药性难题。中药抗细菌感染机制特殊,不易产生耐药性,因此,抗菌中药逐步成为研究重点。
经检索,我们查到了关于防治伤口感染中药的药液的公开文献如下:
1.中国专利,申请(专利)号:CN200410102766.7名称:治疗疮疡和伤口感染的中药组合物;公开(公告)号:CN1651012申请(专利权)人:孟庆娟;地址:100085北京市海淀区清上园1号楼2单元102号;摘要:本发明提供了一种治疗疮疡和伤口感染的中药组合物,主要由下列重量份的原料药制成:大豆油1000-1400份、柳树皮250-300份、乳香4-6份、没药4-6份、血竭3-5份和乌蛇170-230份。本发明药物用于治疗伤口感染,可起到消肿止痛,逐淤排脓作用,促使伤口肉芽组织生长,加速其愈合。
2.中国专利,申请(专利)号:CN200910143182.7名称:一种治疗外科伤口感染的中药外用制剂药品及制造方法;公开(公告)号:CN101543565申请(专利权)人:卜继武;地址:161041黑龙江省齐齐哈尔市富拉尔基区铁西国宝小区二栋3单元301室;摘要:一种治疗外科伤口感染的中药外用制剂药品及制造方法。由炮山甲、血竭、三七、赤石脂、乳香、没药、银朱、儿茶、珍珠粉、煅龙骨、轻粉、冰片、芝麻油等中药材为原料,药性平和,无毒副作用,用药少,换药简单,功效好,组方紧扣化腐提毒,活血化瘀,生肌收口,补气益血,治标又治本,疗效快速显著,治愈周期短,治愈率高;制造方法符合传统中医工艺,设备简单,生产周期短,节能节水,产品成本低,无污染,解除了外科常规治疗伤口感染中因为频繁更换外敷药品和手术多次清除坏死感染组织而带来的不良反应。
3.中国专利,申请号:CN201210435957.X名称:治疗伤口感染的药物,公开(公告)号:CN102920776A,申请(专利权)人:苏甲臣,发明(设计)人:苏甲臣;地址:河南省襄城县十里铺乡四里营村11组摘要:本发明公开了一种治疗伤口感染的药物,属医药产品技术领域。本发明药物由巴豆、蓖麻子、坏胡桃和生猪板油组成。制成糊剂必须在青石板上用青石器砸成。生猪板油尽可能采用腊月备用的陈油。四味中药配伍,共奏独特疗效。本发明药物是采用纯天然植物、动物为原料,按一定工艺制备而成的药物组合物,对皮肤伤口感染有独特疗效,不仅疗效高,且愈后不复发。本发明药物所用原料来源广泛,成本低廉,制备方法简单,生产中无三废排放。
4.中国专利,申请号:CN200410021772.X名称:一种治疗伤口感染的消炎止痛外用中药,公开(公告)号:CN1650913,申请(专利权)人:杨德荣,发明(设计)人:杨德荣;地址:四川省成都市蒲江县敦厚乡马湖村二组摘要:本发明公开了一种治疗伤口感染的消炎止痛外用中药,按重量百分比计包括有下述组份:牡丹皮30-35%,板蓝根18-23%,香附30-35%,何首乌1-3%,夜交藤2-5%,夜交藤叶8-13%;本发明的优点是:对治疗皮肤破伤、伤口感染、伤口溃疡及疮毒具有消炎、镇痛、使伤口快速癒合的显著疗效。
5.中国专利,申请号:CN201110059294.1名称:一种治疗创伤的外用中药制剂及其制备方法,公开(公告)号:CN102139029A,申请(专利权)人:山东盛宏医药科技有限公司,发明(设计)人:刘希山;地址:山东省潍坊市高新区东风东街3359号摘要:本发明公开了一种治疗创伤的外用中药制剂及其制备方法,主要由以下重量份的原料药:三七25~35份,五倍子35~45份,血蝎25~35份,没药3~10份,小蓟3~10份,降香3~10份粉碎混合,分别加水加热回流提取两次,将药液合并并浓缩,在浓缩液中加入乙醇,放置后吸取上清液,将乙醇分离回收后,得到中药原液,将所述中药原液加纯化水调至中药浓度为50~60wt%,循环搅拌、精滤后灌装、密封得到治疗创伤用中药制剂。本发明采用合理配方和配比,制备的中药制剂用于治疗创伤,不仅止血效果好,结痂快,而且痂不易脱落,减少了伤口感染的机会,提高了治愈效果。
发明内容
本发明的目的是向市场提供一种不同于现有配方的防治伤口感染的中药药液,能够防治伤口感染,疗效显著,无副作用,达到治愈伤口感染的目的。
为了实现上述目的,本发明的技术方案是:
防治伤口感染的中药药液,其特征在于:它是由包括下述重量份数的原料制成的:
白花菜15-20份,一点红10-15份,虎杖10-15份、黄柏10-15份、穿心莲10-15份。
制备方法是:将白花菜、一点红、虎杖、黄柏、穿心莲粉碎,用药物总重量3-5倍清水水煮沸20-30分钟,过滤,滤渣加1-2倍的清水,再煮沸10-15分钟,合并两次滤液,装瓶,无菌消毒。使用方法:直接涂抹于患处。
以上所述的一点红【拉丁学名】Hemigrammusstictus,功能主治,清热,利水,凉血,解毒。治痢疾,腹泻,便血,水肿,肠痈,聤耳,目赤,喉蛾,疔疮,肿毒。①《岭南采药录》:治肠痔泻血,利小儿积虫,治五疳、开胃进食,解鱼毒。②《福建民间草药》:活血消肿,利尿逐水。③《陆川本草》:凉血消炎。治伤口感染红肿。④《南宁市药物志》:止痛,消恶毒大疮,眼结膜炎。⑤《生草药手册》:治乳疮,痢疾。⑥《野生药植图说》:可作麻疹的洗涤剂。⑦《广东中药》Ⅱ:清解大肠湿热,凉血生肌,消肿拔毒。治痢疾、脱肛(配火炭母),麻疹后热毒内困,赤眼,疮疖肿毒,湿疹痒痛,乳疮(外洗或捣敷),小儿生殖器红肿(外洗或内服)
以上所述的白花菜【拉丁学名】solanumphoteinocarpumnakam.etodash,又称苦凉菜、扣子菜、少花龙葵,属茄科一年生草本,在广西、云南、广西一带的沟边、林下阴湿处有分布,广西广东人经常以嫩梢茎叶食用,可作汤、凉拌或炒食。具清热解毒、利尿散血消肿之功,常用于痢疾、淋证、目赤、喉痛、疔疮等。
以上所述的虎杖【拉丁学名】Polygonumcuspidatum,别名假川七、土川七、红三七、三七或日本蓼。虎杖含有蓼甙、有机酸、葡萄糖甙、多糖类等。有清热解毒、清凉解暑、健胃清食作用,是一种蓼科植物。【功能与主治】清热解毒,利胆退黄,祛风利湿,散瘀定痛,止咳化痰。用于关节痹痛,湿热黄疸,经闭,产后瘀血不下,癓瘕,咳嗽痰多,水火烫伤,跌打损伤,痈肿疮毒。
以上所述的黄柏【拉丁学名】CortexPhellodendriChinensis,可入药,性味苦寒,有清热燥湿,泻火除蒸,解毒疗疮之功效。其性寒、味苦,具清热燥湿、泻火解毒等功效,常用于湿热泻痢、黄疸、白带以及热痹、热淋等症。现代研究表明,黄柏含小蘖碱、黄柏酮等主要成分,有抗菌、收敛、消炎的作用。【功能与主治】清热燥湿,泻火解毒,除骨蒸清虚热。用于湿热泻痢,黄疸,带下,热淋,脚气,痿辟,骨蒸劳热,盗汗,遗精,疮疡肿毒,湿疹瘙痒。盐黄柏滋阴降火。用于阴虚火旺,盗汗骨蒸。
以上所述的穿心莲为爵床科植物穿心莲【拉丁学名】Andrographispaniculata(Burm.f.)Nees)的全草或叶。又名春莲秋柳,一见喜,榄核莲、苦胆草、金香草、金耳钩、印度草,苦草等。产于陕西省,江苏省,福建省,湖北省,海南省,广东省,广西自治区等地。有清热解毒、消炎、消肿止痛作用。主治细菌性痢疾、尿路感染、急性扁桃体炎、肠炎、咽喉炎、肺炎和流行性感冒等,外用可治疗疮疖肿毒、外伤感染等。
本发明具有清热解毒、抗菌消炎、预防感染、消肿止痛等作用,能有效防治伤口感染,疗效好,无毒副作用,无耐药性。
本发明中各成分的药理功能是:
一点红活血消肿、凉血生肌、消肿拔毒。
白花菜清热解毒、散血消肿。
虎杖清热解毒、散瘀定痛,对跌打损伤,痈肿疮毒有很好的疗效。
黄柏清热燥湿、泻火解毒,有抗菌、收敛、消炎的作用。穿心莲清热解毒、消炎、消肿止痛。
以上就是本发明防治伤口感染的中药药液及其生产方法,制备过程简单,最大化保留各种原料中多种有效元素。
本发明的有益效果:
1、本发明采用白花菜、一点红、虎杖、黄柏、穿心莲五味中草药加入配方中进行配制,利用中草药自身功效达到防治伤口感染的目的,无副作用,无需担心化学伤害。
2、本发明不添加任何人工添加剂,无抗生素。
3、生产过程简单,没有污染;使用方法简单,简单易用,制作方便;原材料来源广,价格低廉,减轻人们经济负担。
具体实施方式
实施例1
取以下原料:
白花菜15份;
一点红10份;
虎杖10份;
黄柏10份;
穿心莲10份;
制备方法如下:
将白花菜、一点红、虎杖、黄柏、穿心莲,用药物总重量3-5倍清水水煮沸20-30分钟,过滤,滤渣加1-2倍的清水,再煮沸10-15分钟,合并两次滤液,装瓶,无菌消毒。使用方法:直接涂抹于患处。
实施例2
取以下原料:
白花菜17.5份;
一点红12.5份;
虎杖12.5份;
黄柏12.5份;
穿心莲15份;
制备方法如下:
将白花菜、一点红、虎杖、黄柏、穿心莲粉碎,用药物总重量3-5倍清水水煮沸20-30分钟,过滤,滤渣加1-2倍的清水,再煮沸10-15分钟,合并两次滤液,装瓶,无菌消毒。使用方法:直接涂抹于患处。
实施例3
取以下原料:
白花菜20份;
一点红15份;
虎杖15份;
黄柏15份;
穿心莲20份;
制备方法如下:
将白花菜、一点红、虎杖、黄柏、穿心莲粉碎,用药物总重量3-5倍清水水煮沸20-30分钟,过滤,滤渣加1-2倍的清水,再煮沸10-15分钟,合并两次滤液,装瓶,无菌消毒。使用方法:直接涂抹于患处。
应用实施例:
实施例1,
黄某,75岁,退休工人,2013年5月在市场买菜过程中不慎跌倒,膝盖被擦伤,伤口较大,自行包扎后到药店买了点西药涂抹,2天后不见好转,患处开始流脓,并且红肿疼痛。后经朋友介绍开始使用本发明实施例1的药液,每天坚持涂抹患处五次,2天后患处停止流脓并开始结痂。效果很好。
实施例2,
王某某,38岁,办公室白领。王小姐在家里做饭时不慎被滚烫的汤水烫伤,涂抹后不见好转,患处开始起水泡、红肿、疼痛难忍。后经朋友介绍开始使用本发明实施例2的药液,每天坚持涂抹患处五次,2天后患处水泡和红肿消退并开始结痂。效果很好。
实施例3,
覃某某,16岁,中学生。在学校踢球摔倒膝盖受伤,只是用紫药水涂抹,两天不见好转,患处开始红肿、疼痛难忍。后使用本发明实施例3的药液,每天坚持涂抹患处五次,2天后患处红肿消退并开始结痂。效果很好。
Claims (1)
1.防治伤口感染的外用中药药液的制备方法,其特征在于:它是由下述重量份数的原料制成的:
白花菜15-20份、一点红10-15份、虎杖10-15份、黄柏10-15份、穿心莲10-15份;
所述中药药液的制备方法是:将白花菜、一点红、虎杖、黄柏、穿心莲粉碎,用药物总重量3-5倍清水煮沸20-30分钟,过滤,滤渣加1-2倍的清水,再煮沸10-15分钟,合并两次滤液,装瓶,无菌消毒,得到产品;
所述中药药液的使用方法:直接涂抹于患处。
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