CN103550692B - A kind of Chinese medicine composition for the treatment of chronic otitis media and preparation method thereof - Google Patents
A kind of Chinese medicine composition for the treatment of chronic otitis media and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to treatment otitis media Chinese medicine, in particular to a kind of Chinese medicine composition for the treatment of chronic otitis media and preparation method thereof, be made up of according to weight fraction following component: Flos Chrysanthemi Indici 20-30 part, Radix Bupleuri 20-30 part, Herba Menthae 15-20 part, Radix Sophorae Flavescentis 15-20 part, Radix Curcumae 15-20 part, Rhizoma Osmundae 15-20 part, Herba Aristolochiae Mollissimae 8-15 part, Radix Et Rhizoma Rhei 8-15 part, Radix Angelicae Dahuricae 8-15 part, Rhizoma Phragmitis 8-15 part, Radix Glycyrrhizae 3-5 part.Reasonable recipe of the present invention, heat-clearing and toxic substances removing, dispelling wind suppressing the hyperactive liver, regulating qi to disperse stagnation, expelling wind and removing dampness, instant effect, and effectively cure chronic otitis media disease, stable curative effect, has no side effect.
Description
Technical field
The present invention relates to treatment otitis media Chinese medicine, particularly a kind of Chinese medicine composition for the treatment of chronic otitis media and preparation method thereof.
Background technology
Otitis media is the inflammatory lesion of involving middle ear (comprising pharyngotympanic tube, tympanum, tympanic antrum and mastoid air cell) all or part of structure, is apt to occur in child.Apyetous and suppurative two large classes can be divided into.Apyetous person comprises secretory otitis media, barotraumatic otits media etc., and suppurative person has acute and chronic dividing.Specific inflammatory is shown in very little, as tuberculous otitis media etc.
Western medical treatment otitis media is main mainly with simple type local application, with aqueous topical antibiotics or antibiotic and steroid hormones mixed liquor, as 0.25% chloromycetin solution, chloromycetin cortisone liquid, ofloxacin ear drops etc., and treatment otitis media and otitis externa etc.Soon effective, but cure the symptoms, not the disease, and disease is easily repeatedly.
Primary disease is called " otopyosis ", " chronic suppurative otitis media " by the traditional Chinese medical science.Think because of dampness-heat in the liver and gallbladder, pathogen is prevailing and cause.Treatment by Chinese herbs otitis media has dividing of deficiency and excess.The cardinal symptom of excess syndrome is in ear feeling of distension and oppression, and otalgia, red complexion are red, auditory dysesthesia, tinnitus, and auditory meatus pus Huang is thick.
Summary of the invention
For the defect existed in prior art, the object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine composition to the treatment chronic otitis media of human non-toxic's side effect.
Technical scheme of the present invention is as follows:
Treat a Chinese medicine composition for chronic otitis media, be made up of according to weight fraction following component:
Flos Chrysanthemi Indici 20-30 part, Radix Bupleuri 20-30 part, Herba Menthae 15-20 part, Radix Sophorae Flavescentis 15-20 part, Radix Curcumae 15-20 part, Rhizoma Osmundae 15-20 part, Herba Aristolochiae Mollissimae 8-15 part, Radix Et Rhizoma Rhei 8-15 part, Radix Angelicae Dahuricae 8-15 part, Rhizoma Phragmitis 8-15 part, Radix Glycyrrhizae 3-5 part.
On the basis of above scheme, a kind of Chinese medicine composition for the treatment of chronic otitis media, is made up of according to weight fraction following component:
Flos Chrysanthemi Indici 25 parts, Radix Bupleuri 25 parts, Herba Menthae 18 parts, Radix Sophorae Flavescentis 18 parts, Radix Curcumae 18 parts, Rhizoma Osmundae 18 parts, Herba Aristolochiae Mollissimae 10 parts, Radix Et Rhizoma Rhei 10 parts, the Radix Angelicae Dahuricae 10 parts, Rhizoma Phragmitis 10 parts, 4 parts, Radix Glycyrrhizae.
Flos Chrysanthemi Indici: be slightly cold; Pungent, bitter; Return lung, Liver Channel.Heat-clearing and toxic substances removing; Dispelling wind suppressing the hyperactive liver, detumescence.To staphylococcus aureus, diphtheria corynebacterium, streptococcus, bacillus pyocyaneus, puncture Shigella, influenza virus, all there is inhibitory action.
Radix Bupleuri: cold nature, bitter in the mouth, pungent, return Liver Channel, gallbladder meridian, tool depressed liver-energy dispersing and function of gallbladder promoting, dredge gas resolving depression, loose effect of fire.Expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Cure cold heating, cold and heat deficient fever.Children's's varioliform exanthema waste heat, emaciation and sallow complexion abdominal part expands, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, and uterus comes off, menoxenia.
Herba Menthae: pungent is cool.Return liver lung.Disperse wind heat, clearing throat, rash is detoxified, dispersing the stagnated live-QI to relieve the stagnation of QI, for affection due to external wind and heat and epidemic febrile disease from the beginning of cold, the headache of heating, micro evil wind.For irritability stasis, card see uncomfortable in chest, pain etc.
Radix Sophorae Flavescentis: bitter in the mouth; Cold in nature.Return liver; Kidney; Large intestine; Small intestine meridian; Bladder; Heart channel; Urinary bladder channel.Heat clearing and damp drying; Wind dispelling insecticide.Main damp-heat dysentery; Discharging fresh blood stool; Jaundice; Dysuria; Edema; Leukorrhagia; Pudendal pruritus; Scabies; Leprosy; Skin pruritus; Noxious dampness skin infection.
Radix Et Rhizoma Rhei: bitter, cold.Return through stomach warp; Large intestine channel; Liver Channel; Spleen channel, stasis removing; Clearing away damp-heat; Purging fire and cooling blood; Clots absorbing stimulates the menstrual flow; Removing toxic substances.
Rhizoma Osmundae: bitter, is slightly cold.Slightly poisonous.Return liver, spleen channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis, parasite killing.For anemopyretic cold, pyretic toxicity sends out speckle, hot liver.
Radix Curcumae: acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian, there is the use of regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire.
Herba Aristolochiae Mollissimae: bitter in the mouth is flat.Return Liver Channel.Wind-damp dispelling, the meridian dredging, pain relieving.For rheumatic arthralgia, numb limbs and tense tendons, muscles and bones contracture, traumatic injury pain.
The Radix Angelicae Dahuricae: pungent, temperature.Enter lung, spleen, stomach warp.For Yangming Channel guiding drug.Expelling wind and removing dampness; Logical surreptitiously pain relieving; Detumescence and apocenosis.Main headache due to common cold; Supraorbital bone pain; Toothache; Nasal obstruction; Nasal sinusitis; Domination of damp pathogen chronic diarrhea; Women leucorrhea; Ulcer sores; Venom.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.Induce sweat cold expelling, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Rhizoma Phragmitis: sweet, cold.Return lung meridian, stomach warp.Clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.
Radix Glycyrrhizae: sweet, flat, cardiopulmonary, return taste warp, QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain.
The etiology and pathogenesis of herpes zoster is discussed a lot of, it is generally acknowledged and wind, wet, heat, evil relevant, and how by depression of liver-QI, retention of damp-heat in the interior, impression poison is evil, and Shi Re Bing Pian is fought mutually knot, stops up stagnant skin for trouble.
In the Chinese medicine composition for the treatment of chronic otitis media of the present invention, Flos Chrysanthemi Indici, Radix Bupleuri have heat-clearing and toxic substances removing, dispelling wind suppressing the hyperactive liver, and dredging effect of gas resolving depression, is monarch drug; Herba Menthae, Radix Sophorae Flavescentis, Radix Curcumae, Rhizoma Osmundae has heat clearing and damp drying, stasis removing, effect of heat-clearing and toxic substances removing, and monarch drug dispersing the stagnated live-QI to relieve the stagnation of QI assisted by above-mentioned all medicines, and heat-clearing and toxic substances removing is the ministerial drug of we; Herba Aristolochiae Mollissimae, Radix Et Rhizoma Rhei, the Radix Angelicae Dahuricae, Rhizoma Phragmitis, has effect of regulating qi to disperse stagnation, the meridian dredging, expelling wind and removing dampness, clearing away heat and promoting production of body fluid, and for assistant makes, assist monarch drug and the further regulating the flow of QI to dissipate blood stasis of ministerial drug, detoxify eliminating evil gas; Radix Glycyrrhizae, has QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, must make medicine for our, assists all medicines to form its power of republicanism.Find through clinical practice, have unique curative effect to chronic otitis media, all medicines play heat-clearing and toxic substances removing altogether, dispelling wind suppressing the hyperactive liver, regulating qi to disperse stagnation, effect of expelling wind and removing dampness, reach the object for the treatment of chronic otitis media.
The present invention also discloses the preparation method of the Chinese medicine composition of above-mentioned treatment chronic otitis media, it is characterized in that: comprise the following steps,
(1) described component is mixed in proportion, is ground into powder;
(2) by step (1) obtain powder add in the water of 40 degree soak 6 hours ~ 12 hours, with slow fire boiling, decocting time is 3 hours ~ 5 hours, decoction liquor is filtered, obtain the first filtrate, the quality of the water added is 2 ~ 4 times of the powder quality that the first step obtains;
(3) step (2) is filtered the filtering residue obtained again to add in cold water, with slow fire boiling 2 hours ~ 4 hours, filter acquisition second filtrate, the quality of the water added is 2 ~ 4 times of the powder quality that second step obtains;
(4) merge twice filtrate, obtain described decoct.
Advantage of the present invention is: reasonable recipe, heat-clearing and toxic substances removing, dispelling wind suppressing the hyperactive liver, regulating qi to disperse stagnation, expelling wind and removing dampness, instant effect, and effectively cures chronic otitis media disease, and stable curative effect, has no side effect.
Detailed description of the invention
Embodiment 1
Treat a Chinese medicine composition for chronic otitis media, be made up of (every part of 1g) according to weight fraction following component:
Flos Chrysanthemi Indici 25 parts, Radix Bupleuri 25 parts, Herba Menthae 18 parts, Radix Sophorae Flavescentis 18 parts, Radix Curcumae 18 parts, Rhizoma Osmundae 18 parts, Herba Aristolochiae Mollissimae 10 parts, Radix Et Rhizoma Rhei 10 parts, the Radix Angelicae Dahuricae 10 parts, Rhizoma Phragmitis 10 parts, 4 parts, Radix Glycyrrhizae.
(1) described component is mixed in proportion, is ground into powder;
(2) step (1) is obtained powder to add in the water of 40 degree and soak 8 hours, with slow fire boiling, decocting time is 4 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 3 times of the powder quality that the first step obtains;
(3) step (2) is filtered the filtering residue obtained again to add in cold water, with slow fire boiling 3 hours, filter acquisition second filtrate, the quality of the water added is 3 times of the powder quality that second step obtains;
(4) merge twice filtrate, obtain described decoct.
Instructions of taking: every day 1 dose.Often take medicine and decoct twice, altogether fried 200ml, sooner or later respectively take 100ml.
Embodiment 2
Treat a Chinese medicine composition for chronic otitis media, be made up of (every part of 1g) according to weight fraction following component:
Flos Chrysanthemi Indici 20 parts, Radix Bupleuri 20 parts, Herba Menthae 15 parts, Radix Sophorae Flavescentis 15 parts, Radix Curcumae 15 parts, Rhizoma Osmundae 15 parts, Herba Aristolochiae Mollissimae 8 parts, Radix Et Rhizoma Rhei 8 parts, the Radix Angelicae Dahuricae 8 parts, Rhizoma Phragmitis 8 parts, Radix Glycyrrhizae 3-5 part.
(1) described component is mixed in proportion, is ground into powder;
(2) step (1) is obtained powder and add immersion 6 in the water of 40 degree, with slow fire boiling, decocting time is 5 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 4 times of the powder quality that the first step obtains;
(3) step (2) is filtered the filtering residue obtained again to add in cold water, with slow fire boiling 4 hours, filter acquisition second filtrate, the quality of the water added is 4 times of the powder quality that second step obtains;
(4) merge twice filtrate, obtain described decoct.
Instructions of taking: every day 1 dose.Often take medicine and decoct twice, altogether fried 200ml, sooner or later respectively take 100ml.
Embodiment 3
Treat a Chinese medicine composition for chronic otitis media, be made up of (every part of 1g) according to weight fraction following component:
Flos Chrysanthemi Indici 30 parts, Radix Bupleuri 30 parts, Herba Menthae 20 parts, Radix Sophorae Flavescentis 20 parts, Radix Curcumae 20 parts, Rhizoma Osmundae 20 parts, Herba Aristolochiae Mollissimae 15 parts, Radix Et Rhizoma Rhei 15 parts, the Radix Angelicae Dahuricae 15 parts, Rhizoma Phragmitis 15 parts, Radix Glycyrrhizae 3-5 part.
(1) described component is mixed in proportion, is ground into powder;
(2) step (1) is obtained powder to add in the water of 40 degree and soak 12 hours, with slow fire boiling, decocting time is 3 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 2 times of the powder quality that the first step obtains;
(3) step (2) is filtered the filtering residue obtained again to add in cold water, with slow fire boiling 2 hours, filter acquisition second filtrate, the quality of the water added is 2 times of the powder quality that second step obtains;
(4) merge twice filtrate, obtain described decoct.
Every day 1 dose.Often take medicine and decoct twice, altogether fried 200ml, sooner or later respectively take 100ml.
Experimental example:
1. physical data
Choose patients with chronic otitis media 200 example, wherein routine female 112 example of man 88, the oldest 86 years old, minimum 21 years old, 55 years old mean age, the course of disease was the longest 3 years, the shortest 3 months; Patient is divided into four groups at random, often organizes 50 examples, be respectively: treatment group 1, treatment group 2, treatment group 3 and matched group, each group patient age symptom is formed without significant difference.
2. Therapeutic Method
The medicine that treatment group 1 is prepared by embodiment 1; The medicine that treatment group 2 is prepared by embodiment 2; The medicine that treatment group 3 is prepared by embodiment 3; Take according to the using method in embodiment, the course for the treatment of is 10 days.Matched group not medication.
3. diagnostic criteria
Effective: ear is stifled, tinnitus symptom disappears, and audition is increased to normally; Pure tone test detects moral integrity and leads difference within 10dB; Acoustic impedance checks that tympanogram is A type curve, and peak value is 0.3 ~ 1.5mm.Cochleostapedial reflex is drawn.
Effective: ear is stifled, tinnitus symptom alleviates, and audition is improved; Pure tone test detects before conductance is comparatively treated and improves 10 ~ 15dB, but does not reach normal, and acoustic impedance checks that tympanogram is As type curve, and peak value compared with normal is on the low side.
Invalid: clinical symptoms is without improvement, and it is effectively total effective rate that every inspection is not improved effective adding.
4. therapeutic effect
| Cure | Effective | Effectively | Invalid | Total effective rate | |
| Treatment group 1 | 25 | 12 | 8 | 5 | 90% |
| Treatment group 2 | 23 | 15 | 6 | 6 | 88% |
| Treatment group 3 | 22 | 16 | 6 | 6 | 88% |
| Matched group | 0 | 0 | 0 | 50 | 0 |
Taboo: menstrual phase women and contraindication in pregnancy.
Untoward reaction: in this experiment, experimental group, matched group are showed no obvious adverse reaction.
All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (2)
1. treat a Chinese medicine composition for chronic otitis media, be made up according to parts by weight of following component:
Flos Chrysanthemi Indici 20-30 part, Radix Bupleuri 20-30 part, Herba Menthae 15-20 part, Radix Sophorae Flavescentis 15-20 part, Radix Curcumae 15-20 part, Rhizoma Osmundae 15-20 part, Herba Aristolochiae Mollissimae 8-15 part, Radix Et Rhizoma Rhei 8-15 part, Radix Angelicae Dahuricae 8-15 part, Rhizoma Phragmitis 8-15 part, Radix Glycyrrhizae 3-5 part;
The preparation method of this Chinese medicine composition comprises the following steps,
(1) described component is mixed in proportion, is ground into powder;
(2) by step (1) obtain powder add in the water of 40 degree soak 6 hours ~ 12 hours, with slow fire boiling, decocting time is 3 hours ~ 5 hours, decoction liquor is filtered, obtain the first filtrate, the quality of the water added is 2 ~ 4 times of the powder quality that the first step obtains;
(3) step (2) is filtered the filtering residue obtained again to add in cold water, with slow fire boiling 2 hours ~ 4 hours, filter acquisition second filtrate, the quality of the water added is 2 ~ 4 times of the powder quality that second step obtains;
(4) merge twice filtrate, obtain decoct.
2. the Chinese medicine composition for the treatment of chronic otitis media according to claim 1, be made up according to parts by weight of following component:
Flos Chrysanthemi Indici 25 parts, Radix Bupleuri 25 parts, Herba Menthae 18 parts, Radix Sophorae Flavescentis 18 parts, Radix Curcumae 18 parts, Rhizoma Osmundae 18 parts, Herba Aristolochiae Mollissimae 10 parts, Radix Et Rhizoma Rhei 10 parts, the Radix Angelicae Dahuricae 10 parts, Rhizoma Phragmitis 10 parts, 4 parts, Radix Glycyrrhizae.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102657705A (en) * | 2012-05-22 | 2012-09-12 | 王永红 | Medicine for treating tympanitis and preparation method thereof |
| CN102671061A (en) * | 2012-04-20 | 2012-09-19 | 许梅 | Traditional Chinese medicine for treating chronic suppurative otitis media, as well as application and preparation method of same |
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| CN102671061A (en) * | 2012-04-20 | 2012-09-19 | 许梅 | Traditional Chinese medicine for treating chronic suppurative otitis media, as well as application and preparation method of same |
| CN102657705A (en) * | 2012-05-22 | 2012-09-12 | 王永红 | Medicine for treating tympanitis and preparation method thereof |
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