CN103550607A - Traditional Chinese medicine composition for treating chorionic epithelioma - Google Patents
Traditional Chinese medicine composition for treating chorionic epithelioma Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating chorionic epithelioma. The composition comprises the following raw medicines by weight: 18-22 grams of leonurus, 7-12 grams of angelica sinensis, 10-20 grams of white atractylodes rhizome, 18-24 grams of poria cocos, 7-15 grams of lithospermum, 10-15 grams of coix seed, 10-20 grams of dried rehmannia root, 15-20 grams of wolfberry fruit, 15-25 grams of codonopsis pilosula, 5-10 grams of livistona chinensis seed, 5-15 grams of radix trichosanthis and 5-10 grams of seaweed. In the formula of the composition disclosed by the invention, the leonurus, the angelica sinensis and the lithospermum have the effects of activating blood and dissolving stasis; the coix seed has the effects of invigorating spleen and supplementing qi; the dried rehmannia root and the livistona chinensis seed have the effects of nourishing yin, moisturizing lung, removing stasis and stopping bleeding; the codonopsis pilosula, the poria cocos and the white atractylodes rhizome have the effects of nourishing yin, nourishing blood, tonifying spleen and reinforcing kidney; and therefore, through the combination of the raw medicines, the composition has the beneficial effects of increasing the body immunity, reducing the toxic and side effects, inhibiting the tumor growth and effectively killing the tumor cells.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition for the treatment of chorionic epithelioma.
Background technology
Chorionic epithelioma is a kind of rare malignant tumor, and suffering from patient is mainly 35 years old following women.The clinical common sympton of chorionic epithelioma is that vagina continues irregular bleeding, and how much indefinite blood volume is, sometimes also can first occur momentary amenorrhea, then unexpected vaginal hemorrhage.During inspection, can find that uterus increases and softness, out-of-shape; Vagina has caramel and the courageous and upright secretions of special smell; General Symptoms is anemia, becomes thin, very occurs dyscrasia, and accompanying infection can have heating.High because of primary disease grade malignancy, can there is in early days lung and shift, there is the symptoms such as chest pain, cough, spitting of blood, other metastasis sites are vagina, pudendum, pelvic cavity, liver, brain etc., and occur the corresponding symptom of each internal organs.Once morbidity as not in time treatment, patient is often dead in 1 year.
The advantage of western medical treatment is instant effect, but normal because over-treatment causes the adverse consequences that things turn out contrary to one's wishes, and side effect severe patient can cause single system or multisystem nonfunction.Advantages of TCM is the successful of relief of symptoms, and to the secondary in the middle of carcinosis radiotherapy and chemotherapy, iatrogenic infringement has good auxiliary therapeutic action, can treat for cause of disease.
In prior art, the herbal species for the treatment of chorionic epithelioma is more, but raw material variety is various mostly, and preparation technology is comparatively complicated, adds that some raw material is rare valuable medicinal, and to cause the price of medicine higher, patient is difficult to bear; In addition, because some crude drug itself just has very large toxicity, to cause medicine with certain toxicity, often patient is produced to certain side effect.At present, there is no the medicine with same materials compatibility of the present invention.
Summary of the invention
Object of the present invention is exactly, in order to address the above problem, to provide a kind of Chinese medicine composition for the treatment of chorionic epithelioma, and it has, and good effect, expense are low, the advantage such as have no side effect.
To achieve these goals, the present invention adopts following technical scheme:
Treat a Chinese medicine composition for chorionic epithelioma, by the crude drug of following weight, formed: Herba Leonuri 18-22g, Radix Angelicae Sinensis 7-12g, Rhizoma Atractylodis Macrocephalae 10-20g, Poria 18-24g, Radix Arnebiae (Radix Lithospermi) 7-15g, Semen Coicis 10-15g, Radix Rehmanniae 10-20g, Fructus Lycii 15-20g, Radix Codonopsis 15-25g, seed of Livistona chinensis R.Br. 5-10g, Radix Trichosanthis 5-15g, Sargassum 5-10g.
Further, treat a Chinese medicine composition for chorionic epithelioma, by the crude drug of following weight, formed: Herba Leonuri 20g, Radix Angelicae Sinensis 10g, Rhizoma Atractylodis Macrocephalae 15g, Poria 20g, Radix Arnebiae (Radix Lithospermi) 10g, Semen Coicis 12g, Radix Rehmanniae 15g, Fructus Lycii 18g, Radix Codonopsis 20g, seed of Livistona chinensis R.Br. 8g, Radix Trichosanthis 10g, Sargassum 7g.
A kind of preparation method for the treatment of the Chinese medicine composition of chorionic epithelioma is, raw medicinal material is put into marmite, the water soaking 2 hours that adds 4 times of dose weight multiples, decoct 1 hour, filter to obtain medicinal liquid and medicinal residues, to the water that adds again 2 times of doses in medicinal residues, decoct 0.5 hour, filter to obtain medicinal liquid, merge the medicinal liquid of twice, obtain.
The pharmacological action of each component is as follows:
Herba Leonuri: acrid in the mouth; Bitter; Property is micro-to be entered.Enter the heart, liver, urinary bladder channel.Cure mainly and invigorate blood circulation, blood stasis dispelling, regulating menstruation, the water that disappears, controls menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.
Radix Angelicae Sinensis: sweet in the mouth; Pungent; Bitter; Warm in nature.Return liver; The heart; Spleen channel.Main effect: enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturizes laxation.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; Stomach warp.Invigorating the spleen and replenishing QI, invigorating the spleen and regulating the stomach, dampness diuretic; Reduce phlegm, hidroschesis; Antiabortive; Increase appetite.
Poria: sweet, light, flat.GUIXIN warp, lung meridian, spleen channel, kidney channel.Promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming, relieves internal heat anticancer.The property of medicine is gentle, dampness removing and do not hinder healthy energy.
Radix Arnebiae (Radix Lithospermi): cold in nature, sweet in the mouth, salty.GUIXIN, Liver Channel.Cure mainly removing heat from blood, invigorate blood circulation, removing toxic substances rash.For heat in blood poison contain, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire, clearing away heat and cooling blood, for measles, calentura skin eruption, eczema, hematuria, stranguria with blood, dysentery, skin infection, erysipelas, burn, constipation with heat retention.
Semen Coicis: cool in nature, sweet in the mouth, light.Cure mainly spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.
Radix Rehmanniae: heat clearing away, promote the production of body fluid, moisturize, laxation, removing blood stasis with potent drugs, tissue regeneration promoting, pain relieving, regulating menstruation, the incised wound stasis of blood, removing heat from blood, stop blooding, invigorate blood circulation;
Fructus Lycii: sweet, flat.Nourishing the liver, nourishing kidney, lung moistening.
Radix Codonopsis: property is flat, sweet in the mouth, micro-acid.Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Seed of Livistona chinensis R.Br.: sweet, puckery, flat.Return lung, liver, kidney, stomach warp.Can be used for traumatic hemorrhage, women is collapsed the diseases such as lower leakage blood and gastral cavity abdomen mass in the abdomen feeling of distension and oppression pain.
Radix Trichosanthis: sweet, micro-hardship, is slightly cold.Attach to the lung and stomach meridians.For calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin.
Sargassum: bitter in the mouth, salty, cold in nature, nontoxic.Return lung, spleen, kidney, liver stomach warp.Softening the hard mass; Expectorant; Diuretic; Detumescent.
The formation of chorionic epithelioma is main relevant with deficiency of vital QI and many visceral dysfunctions, because visceral-qi is weak, insufficiency of vital energy and blood, therefore in embryo's formation, existing exopathogen invasion is fought mutually with essence and blood, the stagnant vessels of the uterus of the stasis of blood, Fu Yuchong appoints, to childbirth or miscarriage, vessels of the uterus is more empty, and blood stasis stagnates; gradually become mass in the abdomen, treat body healthy energy weaker in and fall ill.Therefore, the main pathology of primary disease is changed into a series of clinical symptoms that deficiency of vital QI, blood-stasis internal-depression, the many functions of damage cause.The treatment of motherland's medical science to primary disease, is mainly reflected in three aspects, with tcm theory, carries out whole determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, adjusts the equilibrium between yin and yang of body; Selection has the Chinese herbal medicine of antitumaous effect and makes decoct, and injection carries out anticancer therapy; The side effect that prevention and treatment chemotherapy produce.In therapeutic process, most important to the adjusting of the maintenance of healthy energy, equilibrium between yin and yang.
Beneficial effect of the present invention: in formula of the present invention, Herba Leonuri, Radix Angelicae Sinensis, Radix Arnebiae (Radix Lithospermi) blood circulation and removing stasis, Semen Coicis invigorating the spleen and benefiting QI; Radix Rehmanniae, seed of Livistona chinensis R.Br. nourishing YIN and moistening the lung, removing stasis to stop bleeding; Radix Codonopsis Poria and bighead atractylodes rhizome Radix Angelicae Sinensis nourishing YIN and benefiting blood, spleen benefiting and strengthen kidney; All medicine compatibilities, can improve immunity of organisms, reduce toxic and side effects, can suppress tumor and grow up, and effectively kill tumor cell.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described; but be not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various modifications that creative work can make or distortion still in protection scope of the present invention.
Embodiment 1:
Treat a Chinese medicine composition for chorionic epithelioma, by the crude drug of following weight, formed: Herba Leonuri 20g, Radix Angelicae Sinensis 10g, Rhizoma Atractylodis Macrocephalae 15g, Poria 20g, Radix Arnebiae (Radix Lithospermi) 10g, Semen Coicis 12g, Radix Rehmanniae 15g, Fructus Lycii 18g, Radix Codonopsis 20g, seed of Livistona chinensis R.Br. 8g, Radix Trichosanthis 10g, Sargassum 7g.
Above-mentioned medical material is put into marmite, add the water soaking 2 hours of 4 times of dose weight multiples, decoct 1 hour, filter to obtain medicinal liquid and medicinal residues, the water to adding again 2 times of doses in medicinal residues, decocts 0.5 hour, filters to obtain medicinal liquid, merges the medicinal liquid of twice, obtains.
Embodiment 2:
Treat a Chinese medicine composition for chorionic epithelioma, by the crude drug of following weight, formed: Herba Leonuri 18g, Radix Angelicae Sinensis 7g, Rhizoma Atractylodis Macrocephalae 10g, Poria 18g, Radix Arnebiae (Radix Lithospermi) 7g, Semen Coicis 10g, Radix Rehmanniae 10g, Fructus Lycii 15g, Radix Codonopsis 15g, seed of Livistona chinensis R.Br. 5g, Radix Trichosanthis 5g, Sargassum 5g.
Above-mentioned medical material is put into marmite, add the water soaking 2 hours of 4 times of dose weight multiples, decoct 1 hour, filter to obtain medicinal liquid and medicinal residues, the water to adding again 2 times of doses in medicinal residues, decocts 0.5 hour, filters to obtain medicinal liquid, merges the medicinal liquid of twice, obtains.
Embodiment 3:
Treat a Chinese medicine composition for chorionic epithelioma, by the crude drug of following weight, formed: Herba Leonuri 22g, Radix Angelicae Sinensis 12g, Rhizoma Atractylodis Macrocephalae 20g, Poria 24g, Radix Arnebiae (Radix Lithospermi) 15g, Semen Coicis 15g, Radix Rehmanniae 20g, Fructus Lycii 20g, Radix Codonopsis 25g, seed of Livistona chinensis R.Br. 10g, Radix Trichosanthis 15g, Sargassum 10g.
Above-mentioned medical material is put into marmite, add the water soaking 2 hours of 4 times of dose weight multiples, decoct 1 hour, filter to obtain medicinal liquid and medicinal residues, the water to adding again 2 times of doses in medicinal residues, decocts 0.5 hour, filters to obtain medicinal liquid, merges the medicinal liquid of twice, obtains.
Clinical data:
(1) clinical subjects
The inventor carries out clinical observation treatment to 60 routine chorionic epithelioma patients, and by blood, routine urianlysis, hepatic and renal function inspection, regularly carries out CT examination.
(2) Therapeutic Method
Wherein randomly draw 30 examples and take the Chinese medicine composition that the embodiment of the present invention 1 boils, one day twice, each 300ml, 15 days is a course for the treatment of, during treatment, the other drug of stopping using; All the other 30 routine patients take fluorouracil, and three times on the one, each 100mg.
(3) curative effect determinate standard
" alleviate completely ": colporrhagia phenomenon is eliminated; Abdominal mass disappears; Have rosy cheeks, extremity are strong; Feed is normal; Without hemoptysis cough phenomenon; Anuria hemafecia blood phenomenon;
" partial rcsponse ": colporrhagia phenomenon is eliminated; Abdominal mass dwindles more than 50%, and feed is normal; Occasionally there is cough, without hemoptysis; Anuria hemafecia blood;
" stablize ": colporrhagia phenomenon is eliminated; Abdominal mass dwindles not as good as 50%, and feed is normal; Occasionally there are cough and hemoptysis phenomenon; Occasionally there is hematuria phenomenon;
" deterioration ": colporrhagia constant or time while flowing only, lower abdomen can touch enclosed mass, pale complexion, the tired lazy speech of body, the whole body is weak, cough or hemoptysis have the hematuria phenomenon of having blood in stool.
(4) therapeutic effect:
Table 1 patient takes the present invention and fluorouracil effect comparison after 30 days
As can be seen from Table 1, the present invention prepares simply, and good absorbing effect is evident in efficacy, has no side effect, safe, is conducive to patient and alleviates in time condition of illness.
Model case:
1, Mrs Li, 28 years old, minute puerperium, colporrhagia constant or time while flowing only, companion's abdominal pain with tenderness, lower abdomen can touch enclosed mass, pale complexion, the tired lazy speech of body, the whole body is weak.Through hospital diagnosis, be chorionic epithelioma, operative treatment is invalid, takes the Chinese medicine composition of the embodiment of the present invention 1 after 2 courses for the treatment of, and colporrhagia stops, and lower abdomen enclosed mass reduces, and health tired out sense alleviates; Continue to take 2 courses for the treatment of, lower abdomen enclosed mass is eliminated, complexion show profit.
2, Mrs Zhao, 31 years old, colporrhagia constant or time while flowing only, abdominal pain with tenderness, have enclosed mass, cough, spitting of blood or sputum mixed with blood, feeling of oppression and pain in the chest, the thirsty or heating of xerostomia, weak, inappetence, red tongue, yellow fur, wiry and frequent pulse.Through hospital, make a definite diagnosis, focus is transferred to pulmonary, and operative treatment is ineffective, take the Chinese medicine composition of the embodiment of the present invention 1 after 3 courses for the treatment of, colporrhagia stops, and lower abdomen enclosed mass reduces, feeling of oppression and pain in the chest sense alleviates, cough, spitting of blood obviously alleviate, and have feed desire, continue to take after 2 courses for the treatment of, lower abdomen enclosed mass is eliminated, feed is normal, occasionally has cough, no longer hemoptysis.
3, Mrs Wang, 35 years old, colporrhagia constant or time while flowing only, or a large amount of hematochezia.Abdominal pain with tenderness, or touch enclosed mass, yellowish complexion body is thin, fatigue and weakness, sweating while acting, inappetence, or cough hemoptysis, or nausea and vomiting, or loose stool, have blood in stool, hematuria, or headache, twitch.Through hospital, make a definite diagnosis, focus is transferred to the portions such as head, digestive tract, kidney, and operative treatment is ineffective, take the Chinese medicine composition of the embodiment of the present invention 1 after 3 courses for the treatment of, colporrhagia stops, and lower abdomen enclosed mass reduces, and cough, spitting of blood obviously alleviate, there is feed desire, night sweat number of times reduces, and has the sensation of feeling sick, but few vomiting, have blood in stool, hematuria number of times reduces, headache sense alleviates; Continue to take after 3 courses for the treatment of, lower abdomen enclosed mass is eliminated, and feed is normal, and freedom of movement, without night sweat phenomenon, occasionally has cough, and no longer hemoptysis, without nausea and vomiting symptom, without having blood in stool hematuria phenomenon, occasionally has slight headache, without tic phenomenon.
Claims (3)
1. a Chinese medicine composition for the treatment of chorionic epithelioma, it is characterized in that, by the crude drug of following weight, formed: Herba Leonuri 18-22g, Radix Angelicae Sinensis 7-12g, Rhizoma Atractylodis Macrocephalae 10-20g, Poria 18-24g, Radix Arnebiae (Radix Lithospermi) 7-15g, Semen Coicis 10-15g, Radix Rehmanniae 10-20g, Fructus Lycii 15-20g, Radix Codonopsis 15-25g, seed of Livistona chinensis R.Br. 5-10g, Radix Trichosanthis 5-15g, Sargassum 5-10g.
2. a kind of Chinese medicine composition for the treatment of chorionic epithelioma as claimed in claim 1, it is characterized in that, by the crude drug of following weight, formed: Herba Leonuri 20g, Radix Angelicae Sinensis 10g, Rhizoma Atractylodis Macrocephalae 15g, Poria 20g, Radix Arnebiae (Radix Lithospermi) 10g, Semen Coicis 12g, Radix Rehmanniae 15g, Fructus Lycii 18g, Radix Codonopsis 20g, seed of Livistona chinensis R.Br. 8g, Radix Trichosanthis 10g, Sargassum 7g.
3. a kind of Chinese medicine composition for the treatment of chorionic epithelioma as claimed in claim 1 or 2, it is characterized in that, preparation method is, raw medicinal material is put into marmite, the water soaking 2 hours that adds 4 times of dose weight multiples, decoct 1 hour, filter to obtain medicinal liquid and medicinal residues, to the water that adds again 2 times of doses in medicinal residues, decoct 0.5 hour, filter to obtain medicinal liquid, merge the medicinal liquid of twice, obtain.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716417A (en) * | 2012-06-15 | 2012-10-10 | 祁连明 | Traditional Chinese medicine preparation for treating gynaecopathia and preparation method of preparation |
| CN102772745A (en) * | 2012-08-21 | 2012-11-14 | 卢速江 | Chinese medicinal preparation for treating cancer and preparation method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716417A (en) * | 2012-06-15 | 2012-10-10 | 祁连明 | Traditional Chinese medicine preparation for treating gynaecopathia and preparation method of preparation |
| CN102772745A (en) * | 2012-08-21 | 2012-11-14 | 卢速江 | Chinese medicinal preparation for treating cancer and preparation method thereof |
Non-Patent Citations (2)
| Title |
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| 刘建平等: "《当代妇科名方验方大全》", 30 April 2011, 广东科技出版社 * |
| 哈孝贤: "漫谈绒毛膜癌及中医的治疗", 《开卷有益.求医问药》 * |
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