CN103550129A - Plant composite polysaccharide and preparation method and application thereof - Google Patents
Plant composite polysaccharide and preparation method and application thereof Download PDFInfo
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Abstract
The invention relates to plant composite polysaccharide and a preparation method and an application thereof. The plant composite polysaccharide is prepared by the following raw materials in parts by weight: 30 to 80 parts of pollen pini, 10 to 40 parts of astragalus membranaceus, 5 to 25 parts of poria cocos, 5 to 20 parts of salviae miltiorrhizae, 3 to 20 parts of angelica sinensis and 2 to 15 parts of liquorice. The plant composite polysaccharide can be used for preparing skincare products with a moistening function, an anti-aging function and a skin repairing function, such as skin cream, skin gel, body lotion, toner and the like. The preparation method of the plant composite polysaccharide adopts a conventional method.
Description
Technical field
The present invention relates to technical field of skin care, particularly relate to plant compound polyose, its preparation method, and the purposes of plant compound polyose in cosmetics preparation.
Background technology
The develop rapidly of modern science and technology and extensive use have brought brand-new opportunity to develop to skin care item industry, the basic skin care item that skin care item have been object from clean skin, skin moistening to slow down aging, beautify the complexion as the effect type skin care item future development of object, chemical beauty treatment, plant beauty have been experienced in the research and development of skin care item, and just the target towards biological beauty and gene beauty treatment strides forward.
Vegetable polysaccharides is a kind of biomacromolecule being extensively present in plant roots stem and leaf, and it is by glycosidic bond polymerization, the ketone group containing that forms of dehydration or the polyhydroxylated polymer of aldehyde radical by a plurality of monosaccharide molecules.It is the important composition composition of human body skin skin corium, it is the very important nutrient substance of organism, in the multiple vital movement of body, bringing into play irreplaceable effect, and closely related with the old and feeble apoptosis of cell recognition, Organism immunoregulation, intercellular substance transportation, cell.Vegetable polysaccharides is the application in skin care item as effect skin care product additive, is an important directions of biological beauty, can produce in moisturizing, slow down aging, promotion that hide fiber becomes cell proliferation and the several functions such as beautify the complexion.In addition, compare with the medicine of chemosynthesis, vegetable polysaccharides also has the feature of low toxicity, so it has boundless development prospect.
In industry, the extraction and preparation technique of the single vegetable polysaccharidess such as Hericium erinaceus (Bull. Ex Fr.) Pers., Agaricus blazei Murrill, Bulbus Allii, Herba Hedyotidis Diffusae, Fructus Jujubae slag, Auricularia, Aloe, the Radix Astragali is studied at present.Conventional extracting method has decoction and alcohol sedimentation technique, diluted alkaline extraction, diluted acid extraction and enzyme process etc.But in skin care item, use the polysaccharide of single prescription can not comprehensively solve variety of issue, therefore be necessary " monarch " theory by the traditional Chinese medical science, the plant containing polysaccharide component with synergistic function is carried out to compound recipe, the extraction and preparation technique after research plant compound recipe.At present, have no the research to plant compound polyose extraction and preparation technique.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of plant compound polyose, its preparation method, and plant compound polyose is applied to have moisturizing, the exploitation of defying age and skin maintenance function skin care item.
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind of plant compound polyose, is prepared from by the crude drug of following weight proportion:
Preferably, plant compound polyose is comprised of the crude drug of following weight proportion:
The present invention is according to " monarch " of theory of Chinese medical science, and selecting main component is the Chinese medicine of polysaccharide, and each medicine act as:
Pollen Pini: sweet in the mouth, temperature.Return liver, spleen channel.Dampness, astringing to arrest bleeding.For eczema, impetigo, skin erosion, pus is dripping, traumatic hemorrhage, diaper dermatitis.Pine pollen polysaccharide has moisturizing, antioxidation, removing free radical, the effect of slow down aging.
Radix Salviae Miltiorrhizae: bitter in the mouth, is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea, breast ventral spine pain, pyretic arthralgia pain, skin ulcer wound swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.Radix Salviae Miltiorrhizae polysaccharide energy promoting blood circulation to restore menstrual flow, has whitening and preserving moisture and protecting skin effect.
The Radix Astragali: nature and flavor are sweet, warm.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.Astragalus polysaccharides mainly contains glucosan and heteropolysaccharide, and research shows at anticoagulation, antithrombotic, antiinflammatory, tune blood fat and reduce the aspects such as blood viscosity to have good efficacy.
Radix Angelicae Sinensis: sweet in the mouth; Pungent; Bitter; Warm in nature.Return liver; The heart; Spleen channel.Enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Radix Angelicae Sinensis polysaccharide has moisture-keeping efficacy, is enriching blood, is removing free radical, improves immunity, there is to remarkable effect the aspects such as antitumor, Antiradiation injury.
Poria: Poria sweet in the mouth, light, property are flat, be used as medicine there is promoting diuresis to eliminate damp pathogen, the function of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Pachyman mainly, by compositions such as pachyman, glucose, sucrose and fructose, has inhibitory action to various bacteria; Have promote cell division, complement activation, mutation, antitumor, anticancer, strengthen the biological activitys such as immunity.
Radix Glycyrrhizae: sweet in the mouth is flat.GUIXIN, spleen, lung, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Angelica Polysaccharide has moisturizing, removes hydroxy radical, regulates immunity, suppresses the skin-care effects such as allergy.
In above-mentioned each crude drug, pine pollen polysaccharide and Radix Salviae Miltiorrhizae polysaccharide have the effect of moisturizing, antioxidation, blood circulation promoting and blood stasis dispelling, defying age, are monarch drug; The Radix Astragali, Radix Angelicae Sinensis polysaccharide benefiting vital QI and blood, be conducive to blood circulation promoting and blood stasis dispelling, can skin whitening be ministerial drug; Pachyman, has promotion cell division, accelerates metabolism, and the effect of moisturizing, is adjuvant drug; Angelica Polysaccharide regulates immunity, suppresses allergy, and coordinating the actions of various ingredients in a prescription, for making medicine.This plant compound polyose is used in skin care item, has synergistic function, moisturizing, the antioxidation of skin protection, enhance metabolism and blood circulation promoting and blood stasis dispelling etc. aspect is comprehensive plays a role, thereby reach real skin protection object.
The preparation method of plant compound polyose as mentioned above, comprises the following steps:
Step 1, takes respectively each crude drug according to plant compound polyose formula consumption;
Step 2; each crude drug is soaked respectively 0.5～2 hour in water; the mass volume ratio of crude drug and water is 1:15～50g/ml; mixed liquor is heated to 80～100 ℃ and be incubated 1.0～3.0 hours; filter mixed liquor and obtain filtering residue and first-time filtrate, a filtering residue is repeated to said extracted process and obtain secondary filtering residue and secondary filtrate;
Step 3, first-time filtrate and secondary filtrate mix homogeneously obtain and mix filtrate, in described mixing filtrate, add the active carbon of 8～20 % by weight to decolour, and then to mixing filtrate, filter;
Step 4, by step 3, obtain filtrate be cooled to 30～50 ℃, carry out vacuum filtration, obtain the filtrate that contains plant compound recipe crude polysaccharides;
Step 5, in the filtrate that contains plant compound recipe crude polysaccharides of 6～12 volumes, add the chloroform of 1 volume and the mixed liquor of n-butyl alcohol, shake 30～60 minutes, chloroform in the mixed liquor of described chloroform and n-butyl alcohol: n-butyl alcohol volume ratio is 4:1, the Denatured protein of centrifugal removal water layer and solvent layer intersection, centrifugal 2～5 times repeatedly, obtain removing the plant compound recipe crude polysaccharides of foreign protein.
Further, in the preparation method of above-mentioned plant compound polyose, the mass volume ratio of step 2 Raw medicine and water is 1:25～30g/ml.
Further, in the preparation method of above-mentioned plant compound polyose, in step 3, filtering is to utilize 200～300 order gauzes to filter.
Further, in the preparation method of above-mentioned plant compound polyose, in step 4, vacuum filtration is that vacuum is 0.05～0.1Mpa with plate-and-frame filtration, and filter plate fineness is 0.1～5 micron.
The application of plant compound polyose of the present invention in cosmetics preparation.Plant compound polyose compositions of the present invention, can make the skin care item of various dosage forms, and as protective skin cream, skin protection gel, skin care milk, surfactant etc., its preparation method is conventional method.Described skin care item preferably include glycerol and/or antiseptic.
The skin protection group product of preparation, are to take the external preparation that plant compound polyose is primary raw material, without any side effects, to skin without any stimulation and untoward reaction.
The using method of skin care item: generally, every day, each was coated with once sooner or later, was applied to face, before smearing, first cleaned and need smear place.Can use every day, there is no dietetic contraindication during using product of the present invention.
The specific embodiment
Below in conjunction with embodiment, principle of the present invention and feature are described, example, only for explaining the present invention, is not intended to limit scope of the present invention.
Embodiment 1
Plant compound polyose in embodiment 1, is prepared from by the crude drug of following weight proportion:
The preparation method of described plant compound polyose, comprises the following steps:
Step 1, takes respectively each crude drug according to plant compound polyose formula consumption;
Step 2; each crude drug is soaked respectively 0.5 hour in water; the mass volume ratio of crude drug and water is 1:25g/ml; mixed liquor is heated to 95 ℃ and be incubated 3.0 hours; filter mixed liquor and obtain filtering residue and first-time filtrate, a filtering residue is repeated to said extracted process and obtain secondary filtering residue and secondary filtrate;
Step 3, first-time filtrate and secondary filtrate mix homogeneously obtain and mix filtrate, in described mixing filtrate, add the active carbon of 16 % by weight to decolour, and then to mixing filtrate, filter;
Step 4, by step 3, obtain filtrate be cooled to 35 ℃, carry out vacuum filtration, obtain the filtrate that contains plant compound recipe crude polysaccharides;
Step 5, in the filtrate that contains plant compound recipe crude polysaccharides of 8 volumes, add the chloroform of 1 volume and the mixed liquor of n-butyl alcohol, shake 50 minutes, chloroform in the mixed liquor of described chloroform and n-butyl alcohol: n-butyl alcohol volume ratio is 4:1, the Denatured protein of centrifugal removal water layer and solvent layer intersection, centrifugal 4 times repeatedly, obtain removing the plant compound recipe crude polysaccharides of foreign protein.
In said method, in step 3, filtering is to utilize 200 order gauzes to filter.In step 4, vacuum filtration is that vacuum is 0.05Mpa with plate-and-frame filtration, and filter plate fineness is 0.1 micron.Adopt described preparation method to extract preferably and be applicable to the plant compound polyose that skin care item are used.
Embodiment 2
Plant compound polyose in embodiment 1, is prepared from by the crude drug of following weight proportion:
The preparation method of described plant compound polyose, comprises the following steps:
Step 1, takes respectively each crude drug according to plant compound polyose formula consumption;
Step 2; each crude drug is soaked respectively 1.0 hours in water; the mass volume ratio of crude drug and water is 1:35g/ml; mixed liquor is heated to 100 ℃; be incubated 2.5 hours; filter mixed liquor and obtain filtering residue and first-time filtrate, a filtering residue is repeated to said extracted process and obtain secondary filtering residue and secondary filtrate;
Step 3, first-time filtrate and secondary filtrate mix homogeneously obtain and mix filtrate, in described mixing filtrate, add the active carbon of 12 % by weight to decolour, and then to mixing filtrate, filter;
Step 4, by step 3, obtain filtrate be cooled to 45 ℃, carry out vacuum filtration, obtain the filtrate that contains plant compound recipe crude polysaccharides;
Step 5, in the filtrate that contains plant compound recipe crude polysaccharides of 12 volumes, add the chloroform of 1 volume and the mixed liquor of n-butyl alcohol, shake 40 minutes, chloroform in the mixed liquor of described chloroform and n-butyl alcohol: n-butyl alcohol volume ratio is 4:1, the Denatured protein of centrifugal removal water layer and solvent layer intersection, centrifugal 5 times repeatedly, obtain removing the plant compound recipe crude polysaccharides of foreign protein.
In said method, in step 3, filtering is to utilize 300 order gauzes to filter.In step 4, vacuum filtration is that vacuum is 0.08Mpa with plate-and-frame filtration, and filter plate fineness is 2 microns.Adopt described preparation method to extract preferably and be applicable to the plant compound polyose that skin care item are used.
Embodiment 3
Plant compound polyose in embodiment 1, is prepared from by the crude drug of following weight proportion:
The preparation method of described plant compound polyose, comprises the following steps:
Step 1, takes respectively each crude drug according to plant compound polyose formula consumption;
Step 2; each crude drug is soaked respectively 2.0 hours in water; the mass volume ratio of crude drug and water is 1:15g/ml; mixed liquor is heated to 80 ℃; be incubated 1.5 hours; filter mixed liquor and obtain filtering residue and first-time filtrate, a filtering residue is repeated to said extracted process and obtain secondary filtering residue and secondary filtrate;
Step 3, first-time filtrate and secondary filtrate mix homogeneously obtain and mix filtrate, in described mixing filtrate, add the active carbon of 20 % by weight to decolour, and then to mixing filtrate, filter;
Step 4, by step 3, obtain filtrate be cooled to 30 ℃, carry out vacuum filtration, obtain the filtrate that contains plant compound recipe crude polysaccharides;
Step 5, in the filtrate that contains plant compound recipe crude polysaccharides of 10 volumes, add the chloroform of 1 volume and the mixed liquor of n-butyl alcohol, shake 30 minutes, chloroform in the mixed liquor of described chloroform and n-butyl alcohol: n-butyl alcohol volume ratio is 4:1, the Denatured protein of centrifugal removal water layer and solvent layer intersection, centrifugal 2 times repeatedly, obtain removing the plant compound recipe crude polysaccharides of foreign protein.
In said method, in step 3, filtering is to utilize 200 order gauzes to filter.In step 4, vacuum filtration is that vacuum is 0.1Mpa with plate-and-frame filtration, and filter plate fineness is 5 microns.Adopt described preparation method to extract preferably and be applicable to the plant compound polyose that skin care item are used.
Embodiment 4
Plant compound polyose in embodiment 1, is prepared from by the crude drug of following weight proportion:
The preparation method of described plant compound polyose, comprises the following steps:
Step 1, takes respectively each crude drug according to plant compound polyose formula consumption;
Step 2; each crude drug is soaked respectively 1.5 hours in water; the mass volume ratio of crude drug and water is 1:50g/ml; mixed liquor is heated to 85 ℃; be incubated 1.0 hours; filter mixed liquor and obtain filtering residue and first-time filtrate, a filtering residue is repeated to said extracted process and obtain secondary filtering residue and secondary filtrate;
Step 3, first-time filtrate and secondary filtrate mix homogeneously obtain and mix filtrate, in described mixing filtrate, add the active carbon of 8 % by weight to decolour, and then to mixing filtrate, filter;
Step 4, by step 3, obtain filtrate be cooled to 50 ℃, carry out vacuum filtration, obtain the filtrate that contains plant compound recipe crude polysaccharides;
Step 5, in the filtrate that contains plant compound recipe crude polysaccharides of 6 volumes, add the chloroform of 1 volume and the mixed liquor of n-butyl alcohol, shake 60 minutes, chloroform in the mixed liquor of described chloroform and n-butyl alcohol: n-butyl alcohol volume ratio is 4:1, the Denatured protein of centrifugal removal water layer and solvent layer intersection, centrifugal 3 times repeatedly, obtain removing the plant compound recipe crude polysaccharides of foreign protein.
In said method, in step 3, filtering is to utilize 200 order gauzes to filter.In step 4, vacuum filtration is that vacuum is 0.06Mpa with plate-and-frame filtration, and filter plate fineness is 4 microns.Adopt described preparation method to extract preferably and be applicable to the plant compound polyose that skin care item are used.
The application of plant compound polyose of the present invention in cosmetics preparation.Plant compound polyose compositions of the present invention, can make the skin care item of various dosage forms, as protective skin cream, skin protection gel, skin care milk, surfactant etc.Preparation method is conventional method.Described skin care item preferably include glycerol and/or antiseptic.
Get plant compound polyose that embodiment 1-4 finally obtains as active effective ingredient, with various adjuvant (as glycerol and/or antiseptic), preparation method is prepared various skin-protection products routinely, as protective skin cream, skin protection gel, skin care milk, surfactant etc.
Test example 1 human skin patch
Materials and methods
1, tested material is protective skin cream
The raw materials of protective skin cream:
A component: Jojoba oil 10g, glyceryl monostearate 2g, cetearyl alcohol 5g, shea butter 4g, olive oil 2g, PEG-100 stearate 4g.
B component: glycerol 5g, butanediol 8g, allantoin 0.1g, xanthan gum 0.2g, deionized water 54.4g.
The resulting plant compound polyose of C component: embodiment 1 5g.
D component: ocean essence 0.1g, Methylisothiazolinone 0.2g.
The preparation preparation method of protective skin cream: skin care item are prepared conventional method.
2, negative control: blank sample
The raw materials of blank sample:
A component: Jojoba oil 10g, glyceryl monostearate 2g, cetearyl alcohol 5g, shea butter 4g, olive oil 2g, PEG-100 stearate 4g.
B component: glycerol 5g, butanediol 8g, allantoin 0.1g, xanthan gum 0.2g, deionized water 59.4g.
C: ocean essence 0.1g, Methylisothiazolinone 0.2g.
The preparation method of blank sample: skin care item are prepared conventional method.
3, experimenter: totally 30 people, male 0 people, female 30 people, at 21～48 years old age, meet experimenter and volunteer inclusion criteria.
4, patch method: select qualified speckle examination device, with closed patch test method, about 0.020ml～the 0.025g of tested material is dripped in speckle examination device, external special adhesive tape sticks in experimenter back, after 24 hours, remove tested material, within 0.5,24,48 hour after removal, observe dermoreaction respectively, by dermoreaction grade scale in < < skin care item hygienic practice > > (version in 2007), record its result.Result of the test is in Table 1.
Table 1 human skin patch result
Human skin patch result shows: in 30 people, skin adverse reaction appears in 0 example; Spot removal and skin care compositions use safety of the present invention is described.
Test example 2 result of use tests
Protective skin cream by test example 1 preparation, carries out the test of 28 days to receptor.Tester is totally 35 people, female's 25 examples, and male 10 examples, the age was from 28～50 years old.35 human face's xerosis cutiss are rough, dimness, and skin has mottle.Using method: for being often coated with beyond the highest heavens 2～3 times.
Use after 7 days skin to start to become to moisten smooth, use after 14 days, face recovers moist, glossy, elasticity, and the colour of skin obviously highlights accounts for 32 examples (91%).Use after 28 days, skin all recovers to moisten smooth, without dry, dimmed state.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (7)
1. a kind of plant compound polyose, is prepared from by the crude drug of following weight proportion:
2. plant compound polyose according to claim 1, is characterized in that,
3. the preparation method of plant compound polyose described in claim 1 or 2, comprises the following steps:
Step 1, takes respectively each crude drug according to plant compound polyose formula consumption;
Step 2; each crude drug is soaked respectively 0.5～2 hour in water; the mass volume ratio of crude drug and water is 1:15～50g/ml; mixed liquor is heated to 80～100 ℃ and be incubated 1.0～3.0 hours; filter mixed liquor and obtain filtering residue and first-time filtrate, a filtering residue is repeated to said extracted process and obtain secondary filtering residue and secondary filtrate;
Step 3, first-time filtrate and secondary filtrate mix homogeneously obtain and mix filtrate, in described mixing filtrate, add the active carbon of 8～20 % by weight to decolour, and then to mixing filtrate, filter;
Step 4, by step 3, obtain filtrate be cooled to 30～50 ℃, carry out vacuum filtration, obtain the filtrate that contains plant compound recipe crude polysaccharides;
Step 5, in the filtrate that contains plant compound recipe crude polysaccharides of 6～12 volumes, add the chloroform of 1 volume and the mixed liquor of n-butyl alcohol, shake 30～60 minutes, chloroform in the mixed liquor of described chloroform and n-butyl alcohol: n-butyl alcohol volume ratio is 4:1, the Denatured protein of centrifugal removal water layer and solvent layer intersection, centrifugal 2～5 times repeatedly, obtain removing the plant compound recipe crude polysaccharides of foreign protein.
4. the preparation method of plant compound polyose according to claim 3, is characterized in that, the mass volume ratio of step 2 Raw medicine and water is 1:25～30g/ml.
5. the preparation method of plant compound polyose according to claim 3, is characterized in that, in step 3, filtering is to utilize 200～300 order gauzes to filter.
6. the preparation method of plant compound polyose according to claim 3, is characterized in that, in step 4, vacuum filtration is that vacuum is 0.05～0.1Mpa with plate-and-frame filtration, and filter plate fineness is 0.1～5 micron.
7. the application in cosmetics preparation according to the plant compound polyose of claim 1-2 any one.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104127352A (en) * | 2014-07-30 | 2014-11-05 | 广州丹奇日用化工厂有限公司 | Cosmetic composition and preparation method thereof |
| CN104489329A (en) * | 2014-12-14 | 2015-04-08 | 河南联合英伟饲料有限公司 | Drug-core type feed particle for resisting canine bacterial diseases and preparation method thereof |
| CN104739710A (en) * | 2015-02-25 | 2015-07-01 | 烟台新时代健康产业日化有限公司 | Skin regeneration compound and use thereof |
| CN107115383A (en) * | 2017-07-06 | 2017-09-01 | 成都华西珐玛生物科技有限公司 | With the skin care/therapeutic combination for preventing and treating dry skin syndrome effect |
-
2013
- 2013-10-28 CN CN201310518596.XA patent/CN103550129B/en active Active
Non-Patent Citations (2)
| Title |
|---|
| 张斌 等: "植物多糖与化妆品的联系", 《辽宁中医药大学学报》, vol. 15, no. 1, 31 January 2013 (2013-01-31), pages 109 - 111 * |
| 贾琳璐 等: "植物多糖的提取及分离的研究进展", 《PROCEEDINGS OF 2010 FIRST INTERNATIONAL CONFERENCE ON CELLULAR; MOLECULAR BIOLOGY; BIOPHYSICS AND BIOENGINEERING (VOLUME 7)》, 25 December 2010 (2010-12-25), pages 432 - 435 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104127352A (en) * | 2014-07-30 | 2014-11-05 | 广州丹奇日用化工厂有限公司 | Cosmetic composition and preparation method thereof |
| CN104489329A (en) * | 2014-12-14 | 2015-04-08 | 河南联合英伟饲料有限公司 | Drug-core type feed particle for resisting canine bacterial diseases and preparation method thereof |
| CN104739710A (en) * | 2015-02-25 | 2015-07-01 | 烟台新时代健康产业日化有限公司 | Skin regeneration compound and use thereof |
| CN104739710B (en) * | 2015-02-25 | 2017-08-25 | 烟台新时代健康产业日化有限公司 | A kind of skin repair compound and application thereof |
| CN107115383A (en) * | 2017-07-06 | 2017-09-01 | 成都华西珐玛生物科技有限公司 | With the skin care/therapeutic combination for preventing and treating dry skin syndrome effect |
| CN107115383B (en) * | 2017-07-06 | 2021-04-27 | 成都华西珐玛生物科技有限公司 | Skin care/treatment composition having skin xerosis syndrome preventing and treating effect |
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