CN103536809A - Traditional Chinese medicine preparation for treating hypertension and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating hypertension and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine preparation for treating hypertension and a preparation method thereof. The effective components of the traditional Chinese medicine preparation are prepared from the following raw materials: Astragalus membranaceus, radix angelicae pubescentis, Eucommia ulmoides, Polygonum multiflorum, sophora flower, water chestnut, felwort, root of Panicum repens, selfheal, mulberry root, root of kudzu vine, cyclocarya paliurus, Hippophae rhamnoides, sunflower flower, spiral seaweed and lotus leaf. The traditional Chinese medicine preparation is prepared from reasonable matched medicinal materials, meets the traditional Chinese medicine and modern pharmacology study theory, and is prepared by the modern advanced pharmaceutical technology; the traditional Chinese medicine preparation has the effects of nourishing the liver, tonifying kidneys, reducing blood pressure and relieving pain, can enhance immunity of the organism, reduce blood lipid and regulate blood fat of human body, and also can be used in adjunctive treatment for preventing atherosclerosis and coronary disease; the traditional Chinese medicine preparation is safe and has no toxic or side effect, avoids relapse after cure of hypertension, has short course of treatment, takes effect quickly, has low cost, and is worth of popularizing and using.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of hypertensive Chinese medicine preparation and preparation method for the treatment of.
Background technology
Hypertension is modal chronic disease, is also the topmost risk factor of cardiovascular and cerebrovascular disease, and apoplexy, myocardial infarction, heart failure and chronic kidney disease are its major complications.Hypertensive hazardness and patient's blood pressure level mutually outside the Pass, also depend on the situation of the other diseases of simultaneous other cardiovascular risk factors, target organ damage and merging.Hypertensive diagnostic criteria be systolic pressure >=140mmHg and (or) diastolic pressure >=90mmHg, according to blood pressure level, be divided into normally, outside normal high value blood pressure and 1,2,3 grade of hypertension, also according to the other diseases of risk factor, target organ damage and merging simultaneously, carry out risk stratification simultaneously.
The common symptom of hypertension has headache, dizzy, irritated, nauseating, vomiting, cardiopalmus, breathes hard, blurred vision etc.Prevalence of Hypertension raises with age growth, women before climacteric prevalence a little less than male, but raise rapidly after climacteric, even higher than male, high latitude cold district prevalence is higher than the warm area of low latitudes, and high altitude localities is higher than low altitude area, and hypertension is relevant with dietary habit, salt and saturated fat are taken in higher, and mean blood pressure level and prevalence are also higher.
Treating hypertensive main purpose is to reduce to greatest extent cardiovascular morbidity and dead total danger, therefore require doctor in the hypertensive while for the treatment of, intervene the clinical disease that all reversibility cardiovascular risk factors of patient, target organ damage and merging exist.For general hyperpietic's blood pressure lowering target, be below 140/90mmHg, for high risk patients such as complication with diabetes or nephropathy, blood pressure should be taken the circumstances into consideration to be down to more low-level in the tolerant situation of patient.
Both domestic and external facts have proved, hypertension is the disease that can prevent and control, reduces hyperpietic's blood pressure level, can obviously reduce apoplexy and the events of heart attack, significantly improves patient's life quality, effectively reduces disease burden.
The hypertensive medicine of existing treatment is cured the symptoms, not the disease mostly, easily recurrence after treatment, in view of the foregoing, we be badly in need of a kind of safely, have no side effect and Chinese medicine preparation evident in efficacy meets hyperpietic's Treatment need.
Summary of the invention
The invention provides a kind of hypertensive Chinese medicine preparation and preparation method for the treatment of, the selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meet Chinese medicine and modern pharmacology research theory, and utilize modern advanced pharmaceutical technology to make, the effect with nourishing liver, invigorating kidney, blood pressure lowering pain relieving, can enhancing human body immunity power, reduce the function of blood fat balance the body blood fat, also the auxiliary treatment that can be used for atherosclerosis and coronary heart disease, safe without toxic side effect, does not recur after more, short treating period, instant effect, with low cost, wide popularization and application on clinic.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A hypertensive Chinese medicine preparation, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Astragali 50-85 part Radix Angelicae Pubescentis 50-85 part Cortex Eucommiae 50-85 part Radix Polygoni Multiflori 50-85 part
Flos Sophorae 46-80 part Corm Eleocharitis 46-80 part Radix Gentianae 40-72 part Radix panici repentics 40-72 part
Spica Prunellae 40-72 part Radix Mori 35-65 part Radix Puerariae 35-65 part Cyclocarya paliurus Iljinskaja 35-65 part
Fructus Hippophae 28-55 part floral disc of sunflower 28-55 part spirulina 21-42 part Folium Nelumbinis 21-42 part.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
74 parts of 74 parts of Radix Polygoni Multiflori of 74 parts of Cortexs Eucommiae of 74 parts of Radix Angelicae Pubescentiss of the Radix Astragali
62 parts of 62 parts of Radix panici repentics of 70 portions of Radix Gentianaes of 70 portions of Corm Eleocharitiss of Flos Sophorae
56 parts of 56 parts of Cyclocarya paliurus Iljinskaja of 56 parts of Radix Puerariaes of 62 parts of Radix Mori of Spica Prunellae
36 parts, 36 parts of Folium Nelumbinis of 46 parts of spirulinas of 46 parts of floral disc of sunflower of Fructus Hippophae.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
66 parts of 66 parts of Radix Polygoni Multiflori of 66 parts of Cortexs Eucommiae of 66 parts of Radix Angelicae Pubescentiss of the Radix Astragali
54 parts of 54 parts of Radix panici repentics of 62 portions of Radix Gentianaes of 62 portions of Corm Eleocharitiss of Flos Sophorae
49 parts of 49 parts of Cyclocarya paliurus Iljinskaja of 49 parts of Radix Puerariaes of 54 parts of Radix Mori of Spica Prunellae
31 parts, 31 parts of Folium Nelumbinis of 40 parts of spirulinas of 40 parts of floral disc of sunflower of Fructus Hippophae.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
58 parts of 58 parts of Radix Polygoni Multiflori of 58 parts of Cortexs Eucommiae of 58 parts of Radix Angelicae Pubescentiss of the Radix Astragali
48 parts of 48 parts of Radix panici repentics of 54 portions of Radix Gentianaes of 54 portions of Corm Eleocharitiss of Flos Sophorae
42 parts of 42 parts of Cyclocarya paliurus Iljinskaja of 42 parts of Radix Puerariaes of 48 parts of Radix Mori of Spica Prunellae
26 parts, 26 parts of Folium Nelumbinis of 34 parts of spirulinas of 34 parts of floral disc of sunflower of Fructus Hippophae.
Treat a preparation method for hypertensive Chinese medicine preparation, comprise following processing step:
(1) get the Radix Astragali, Radix Angelicae Pubescentis, the Cortex Eucommiae, Flos Sophorae, Radix panici repentics, Spica Prunellae, Cyclocarya paliurus Iljinskaja, Fructus Hippophae and spirulina and clean decontamination, put into container, the distilled water that adds 8-12 doubly to measure, soaked after 4-5 hour, boiled 3-4 hour, extracted; Again add 6-8 doubly to measure distilled water, boil 2-3 hour, extract; Finally add 4-6 doubly to measure distilled water, heated and boiled 1-2 hour, extracts; Merge three times extracting solution, filter, filtrate is condensed into the thick paste of relative density 1.10-1.15 at 60 ℃, drying under reduced pressure, standby;
(2) get Radix Polygoni Multiflori, Corm Eleocharitis and Radix Gentianae decontamination and clean, be placed in container and rub, taking juice is standby;
(3) get Radix Mori, Radix Puerariae and Folium Nelumbinis and clean decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 200 order fine powders, standby;
(4) get floral disc of sunflower and immerse 2-3 hour in the yellow wine that 3-4 doubly measures, take out, dry, grind into powder, cross 180 order fine powders, standby;
(5) above-mentioned steps (1)-(4) prepared thick paste, juice and powder are utilized to modern advanced pharmacy science and technology, make tablet, be the described hypertensive Chinese medicine preparation for the treatment of.
The property of medicine of the present invention's Chinese medicine used is as follows:
The Radix Astragali: sweet in the mouth, warm in nature; Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst, chronic nephritis proteinuria, diabetes.Modern medicine study confirmation, the Radix Astragali can be strengthened the contraction of normal heart, and the heart of exhaustion is had to cardiotonic.
Radix Angelicae Pubescentis: acrid in the mouth, hardship, tepor; Return liver, kidney, urinary bladder channel.Expelling wind and dampness, dispersing cold for relieving pain.For anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache.Modern study confirmation, Radix Angelicae Pubescentis has antiinflammatory, analgesia and sedation, and platelet aggregation is had to inhibitory action, and has hypotensive effect.
The Cortex Eucommiae: sweet in the mouth, warm in nature; Return liver, kidney channel.Invigorating the liver and kidney, strong waist knee joint, bone and muscle strengthening, antiabortive.Cure mainly spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is wanted to fall, frequent fetal movement, hypertension.Modern medicine study confirmation, the Cortex Eucommiae has sedation to nerve centre, can strengthen the immunologic function of cell, promotes cortisol secretion and cAMP in plasma and cGMP metabolism.
Radix Polygoni Multiflori: sweet in the mouth, bitterness, slightly warm in nature; Return liver, kidney channel.Cure mainly blood deficiency anemia, Light-headedness, cardiopalmus, insomnia, the soreness of the waist and knees of the hepatic and renal YIN deficiency, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body is empty, rubella pruritus, carbuncle sore, scrofula, hemorrhoid.Modern medicine study confirms, the contained fibrin of Radix Polygoni Multiflori has lytic activity, can reduce the formation of atherosclerotic's thrombosis or microthrombus, can directly reduce or avoid the generation of cardio cerebrovascular affection, improve, correct and prevent and treat the clinical diseases such as cerebrovascular accident.
Flos Sophorae: bitter in the mouth, cold nature; Enter liver, lung, the heart, large intestine channel.Cooling blood for hemostasis, liver heat removing and eyesight improving.Cure mainly discharging fresh blood stool, hemorrhoid hematochezia, dysentery, hematuria, stranguria with blood, metrorrhagia, spits blood, epistaxis, liver-heat headache, conjunctival congestion and swelling pain, carbuncle skin infection.The positive > > of < < book on Chinese herbal medicine carries: " cool large intestine kills infantile malnutrition worm.Control skin sore, erosion of vulva pruritus due to damp pathogen, anal fistula, separates Fructus Myricae rubrae malignant boil, primary sore volt poison." modern medicine study confirms, the contained globulariacitrin of Flos Sophorae can strengthen capillary resistance, improves blood vessel wall fragility, reduces blood pressure, edema, hyperpietic is had to the effect that prevents rupture of blood vessel in brain, also has in addition antiinflammatory action.
Corm Eleocharitis: sweet in the mouth, cold in nature, nontoxic.Promoting the production of body fluid for nourishing the lung, the sharp intestinal that reduces phlegm, diuresis promoting, eliminating carbuncle removing toxic substances, removing heat from blood removing dampness, de-swelling helps digestion.Cure mainly calentura and quench one's thirst, jaundice, conjunctival congestion, laryngopharynx swelling and pain, urine is fervid deficient, affection due to external wind and heat, the diseases such as mass in the abdomen.Modern medicine study confirms, Corm Eleocharitis all has certain inhibitory action to staphylococcus aureus, escherichia coli and bacillus pyocyaneus, and the heat that can disappear removes expectorant, reduces blood pressure.
Radix Gentianae: bitter in the mouth, cold in nature; Return liver, gallbladder meridian.Heat clearing and damp drying, eliminating pathogen in the liver arresting convulsion.Cure mainly jaundice due to damp-heat, urine leaching pain, swelling of the vulva pudendal pruritus, damp-heat vaginal discharge, the feeling of fullness in the head headache of liver and gall excess-fire, conjunctival congestion and swelling pain, deaf ear is swollen, hypochondriac pain bitter taste, calentura convulsion with spasms.< < detailed outline > > carries: " treat throat pain, wind heat night sweat.Fire is posted in liver and gall mutually, have rush down of no help, therefore the gas of the liver benefiting gallbladder of Radix Gentianae, just with its can eliminating pathogen in the liver gallbladder pathogenic heat also.But in large bitter Great Cold, cross probably the injure one's stomach gas of middle hair growth promoting of clothes, the anti-pathogenic fire that helps, also takes Rhizoma Coptidis for a long time instead from the justice of cremate." modern medicine study confirmation; Radix Gentianae has inhibitory action to root nodule bacteria, escherichia coli, bacillus subtilis, Agrobacterium tumefaciens etc., and Radix Gentianae water logging agent has inhibitory action in various degree to dermatophytess such as trichophyton gypseum star nocardias in vitro.
Radix panici repentics: bitter in the mouth, micro-sweet, property is flat.Heat clearing away suppressing the hyperactive liver, eliminating damp, detoxifying, blood circulation promoting and blood stasis dispelling.Cure mainly hypertension, epistaxis, damp-heat vaginal discharge, stranguria with turbid discharge, sinusitis, parotitis, icterohepatitis, venom, traumatic injury.
Spica Prunellae: bitter in the mouth, pungent, cold in nature, nontoxic.Liver heat removing eliminating stagnation, diuresis.Cure mainly the diseases such as pestilence, acute mastitis, ophthalmalgia, jaundice, gonorrhea, hypertension.The medicinal herbs > > among the people of < < science carries: " have diuresis bactericidal action." modern medicine study confirmation, Spica Prunellae decoct can be washed wound, controls suppurative outer disease, and can control hypertension, can make blood pressure drops.
Radix Mori: mildly bitter flavor, cold in nature; Return Liver Channel.Cure mainly infantile convulsion, conjunctival congestion, toothache, bones and muscles pain.< < Nanjing medicinal herbs > among the people > carries: " control bones and muscles pain, hypertension." modern medicine study confirmation, the ethanol of Mulberry Roots and acetone leachate have the effect of Antifungi in vitro, and can reduce blood pressure.
Radix Puerariae: sweet in the mouth, pungent, cool in nature.Cure mainly fever caused by exogenous pathogens headache, hypertension, neck pain, thirsty, quench one's thirst, measles without adequate eruption, heat rash, has loose bowels etc.< < Compendium of Materia Medica > > carries: " Radix Puerariae, cool in nature, gas is put down, sweet in the mouth, tool heat clearing away, pathogenic fire reducing, all effects of toxin expelling." modern pharmacological research shows; the flavone proposing in Radix Puerariae can increase brain and crown vascular flow amount; reduce vascular resistance, can also reduce blood glucose, the isoflavonoid puerarin in Radix Puerariae has certain curative effect to hypertension, hyperlipidemia, hyperglycemia and cardiovascular and cerebrovascular disease.
Cyclocarya paliurus Iljinskaja: acrid in the mouth, micro-hardship, property is flat.Killing parasites for relieving itching, antiinflammatory, pain relieving is dispeled the wind.Modern medicine study confirms, cyclocarya paliurus tea is rich in the organic nutrition compositions such as abundant saponin, flavone, polysaccharide, can active balance human body carbohydrate metabolism, effectively reduce triglyceride and cholesterol, the function with magical natural blood pressure lowering, blood sugar lowering, blood fat reducing has unique effect to strengthening body immunity, antioxidation, defying age, hepatoprotective etc. simultaneously.
Fructus Hippophae: sour in the mouth, puckery, warm in nature.Relieving cough and resolving phlegm, invigorating the stomach and promoting digestion, promoting blood circulation to remove blood stasis.Cure mainly cough with copious phlegm, pulmonary abscess, dyspepsia, abdominal pain due to retention of food, stomachache, enteritis, amenorrhea, traumatic injury congestive edema.Modern medicine study confirmation, study on flavonoids in sea buckthorn has antiinflammation, can promote capillary blood circulation.
Floral disc of sunflower: lightly seasoned, property is flat.Nourishing liver, invigorating kidney, blood pressure lowering pain relieving.For hypertension, headache and dizziness, tinnitus due to deficiency of the kidney, toothache, stomachache, stomachache, dysmenorrhea.
Spirulina: modern medicine study confirms, spirulina can improve immunologic function, reduce blood fat, be mainly used in the auxiliary treatment of cancer, for hyperlipemia, iron deficiency anemia, diabetes, malnutrition, body void etc. has significant curative effect after being ill, and can effectively reduce the function of blood fat balance the body blood fat, can be used for the auxiliary treatment of atherosclerosis and coronary heart disease.
Folium Nelumbinis: bitter in the mouth, property is flat; Return liver, spleen, stomach warp.Clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood is told nosebleed, the metrorrhagia of having blood in stool, blood pressure lowering, blood fat reducing.。Modern study shows, Folium Nelumbinis has effect for reducing blood fat.
The present invention compared with prior art, has following beneficial effect:
The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meets Chinese medicine and modern pharmacology research theory, and utilizes modern advanced pharmaceutical technology to make, the effect with nourishing liver, invigorating kidney, blood pressure lowering pain relieving, can enhancing human body immunity power, reduce the function of blood fat balance the body blood fat, also can be used for the auxiliary treatment of atherosclerosis and coronary heart disease, safe without toxic side effect, more after, do not recur short treating period, instant effect, with low cost, wide popularization and application on clinic.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Radix Astragali 82g Radix Angelicae Pubescentis 82g Cortex Eucommiae 82g Radix Polygoni Multiflori 82g
Flos Sophorae 78g Corm Eleocharitis 78g Radix Gentianae 70g Radix panici repentics 70g
Spica Prunellae 70g Radix Mori 63g Radix Puerariae 63g Cyclocarya paliurus Iljinskaja 63g
Fructus Hippophae 52g floral disc of sunflower 52g spirulina 40g Folium Nelumbinis 40g.
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) get the Radix Astragali, Radix Angelicae Pubescentis, the Cortex Eucommiae, Flos Sophorae, Radix panici repentics, Spica Prunellae, Cyclocarya paliurus Iljinskaja, Fructus Hippophae and spirulina and clean decontamination, put into container, the distilled water that adds 8-12 doubly to measure, soaked after 4-5 hour, boiled 3-4 hour, extracted; Again add 6-8 doubly to measure distilled water, boil 2-3 hour, extract; Finally add 4-6 doubly to measure distilled water, heated and boiled 1-2 hour, extracts; Merge three times extracting solution, filter, filtrate is condensed into the thick paste of relative density 1.10-1.15 at 60 ℃, drying under reduced pressure, standby;
(2) get Radix Polygoni Multiflori, Corm Eleocharitis and Radix Gentianae decontamination and clean, be placed in container and rub, taking juice is standby;
(3) get Radix Mori, Radix Puerariae and Folium Nelumbinis and clean decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 200 order fine powders, standby;
(4) get floral disc of sunflower and immerse 2-3 hour in the yellow wine that 3-4 doubly measures, take out, dry, grind into powder, cross 180 order fine powders, standby;
(5) above-mentioned steps (1)-(4) prepared thick paste, juice and powder are utilized to modern advanced pharmacy science and technology, make tablet, be the described hypertensive Chinese medicine preparation for the treatment of.
Usage and dosage: oral, warm water delivery service after meal, every day 3 times, each 27 days is a course for the treatment of, and can cure four to six courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Radix Astragali 74g Radix Angelicae Pubescentis 74g Cortex Eucommiae 74g Radix Polygoni Multiflori 74g
Flos Sophorae 70g Corm Eleocharitis 70g Radix Gentianae 62g Radix panici repentics 62g
Spica Prunellae 62g Radix Mori 56g Radix Puerariae 56g Cyclocarya paliurus Iljinskaja 56g
Fructus Hippophae 46g floral disc of sunflower 46g spirulina 36g Folium Nelumbinis 36g.
The present embodiment Chinese medicine preparation preparation method processing step usage and dosage is identical with embodiment 1.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Radix Astragali 66g Radix Angelicae Pubescentis 66g Cortex Eucommiae 66g Radix Polygoni Multiflori 66g
Flos Sophorae 62g Corm Eleocharitis 62g Radix Gentianae 54g Radix panici repentics 54g
Spica Prunellae 54g Radix Mori 49g Radix Puerariae 49g Cyclocarya paliurus Iljinskaja 49g
Fructus Hippophae 40g floral disc of sunflower 40g spirulina 31g Folium Nelumbinis 31g.
The present embodiment Chinese medicine preparation preparation method processing step usage and dosage is identical with embodiment 1.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Radix Astragali 58g Radix Angelicae Pubescentis 58g Cortex Eucommiae 58g Radix Polygoni Multiflori 58g
Flos Sophorae 54g Corm Eleocharitis 54g Radix Gentianae 48g Radix panici repentics 48g
Spica Prunellae 48g Radix Mori 42g Radix Puerariae 42g Cyclocarya paliurus Iljinskaja 42g
Fructus Hippophae 34g floral disc of sunflower 34g spirulina 26g Folium Nelumbinis 26g.
The present embodiment Chinese medicine preparation preparation method processing step usage and dosage is identical with embodiment 1.
Clinical data:
1, case selection:
As the hypertensive Chinese medicine preparation for the treatment of, select hyperpietic's 160 examples to carry out clinical observation, male's 86 examples wherein, women's 74 examples, age 40-70 year, mean age (58 ± 1.3) year.160 routine patients are divided into two groups at random, matched group 80 examples, male 44 examples wherein, women's 36 examples, age 40-70 year, year mean age (58 ± 2.1); Treatment group 80 examples, male's 42 examples wherein, women's 38 examples, age 40-70 year, year mean age (58 ± 3.3).Two groups of patients no difference of science of statistics aspect the ordinary circumstances such as age, sex, the state of an illness, has comparability.
2, Therapeutic Method:
Two groups of patients are diet etc. in accordance with regulations all.Treatment group patient takes Chinese medicine preparation of the present invention, oral, warm water delivery service after meal, and every day 3 times, each 27 days is a course for the treatment of, takes continuously four to six courses for the treatment of, the person of being in a bad way follows the doctor's advice and drinks the amount of adding; Matched group is taken nifedipine, takes to specifications.
3, efficacy assessment standard:
Cure: patient's blood pressure recovers normal, the transference cures such as dizziness and nausea, it is normal that metabolism recovers.
Take a turn for the better: patient's blood pressure recovers to some extent, and the symptoms such as dizziness and nausea are alleviated to some extent.
Invalid: symptom after taking medicine is unchanged.
4, result:
Treatment group: cure 56 examples, 20 examples that take a turn for the better, invalid 4 examples, cure rate 70%, total effective rate 95%.
Matched group: cure 32 examples, 21 examples that take a turn for the better, invalid 27 examples, cure rate 40%, total effective rate 66.3%.
Above result confirms, selects the cure rate for the treatment of group of Chinese medicine preparation of the present invention and total effective rate apparently higher than matched group.
5, model case is for example:
(1) what certain, female, 45 years old, lawyer, Taiyuan, Shanxi people.Patient suffers from hypertension 10 years, and over nearly 2 years, blood pressure continues, in 25.3/14.6kpa (190/110mmhg) left and right, to take nifedipine unsatisfactory curative effect.Rear patient is because of excited, and severe headache, vomits and be ejection suddenly, dizzy, then blurring of vision, upper limb is twitched, and after admission examination, through doctor, recommends, and patient starts to take Chinese medicine preparation of the present invention, take medicine after 5 courses for the treatment of, it is normal that patient's blood pressure recovers, and state of an illness recovery from illness, follows up a case by regular visits to and have no recurrence.
(2) beam, man, 52 years old, college professor, Heze City, Shandong Province people.Patient suffers from and has hypertension, and cardiac blood supply deficiency often can be dizzy.Lai Wo institute checks, has an electro-cardiogram to check and find when heart beating is minimum to only have more than 50, and rear patient takes medicine of the present invention after 2 courses for the treatment of, and it is good that the state of an illness is recovered, and blood pressure decreases, and continues to take 3 courses for the treatment of of medicine of the present invention, and it is normal that blood pressure recovers, and gets well.
(3) permitted certain, man, 58 years old, civil servant, people from Shiyan, Hainan.Patient suffers from hypertension, hyperlipidemia, attempts a lot of method effects all unstable, and a lot of medicines are returned patient and brought many side effect, often dizzy, feels sick, vomiting, stomachache, takes Chinese medicine preparation of the present invention after 4 courses for the treatment of, and it is normal that patient's blood pressure recovers.
(4) appoint certain, female, 64 years old, retired worker, Luoyang, henan people.Patient suffers from hypertension for many years, and scorching with anemia, stomachache and strength vertebra, and often dizzy, trick acid is unable, and strength vertebra pain, has a stomach upset.Take medicine of the present invention after 6 courses for the treatment of, it is normal that patient's blood pressure recovers, and health is also got well thereupon, follows up a case by regular visits to and has no recurrence.
Claims (5)
1. treat a hypertensive Chinese medicine preparation, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Astragali 50-85 part Radix Angelicae Pubescentis 50-85 part Cortex Eucommiae 50-85 part Radix Polygoni Multiflori 50-85 part
Flos Sophorae 46-80 part Corm Eleocharitis 46-80 part Radix Gentianae 40-72 part Radix panici repentics 40-72 part
Spica Prunellae 40-72 part Radix Mori 35-65 part Radix Puerariae 35-65 part Cyclocarya paliurus Iljinskaja 35-65 part
Fructus Hippophae 28-55 part floral disc of sunflower 28-55 part spirulina 21-42 part Folium Nelumbinis 21-42 part.
2. a kind of hypertensive Chinese medicine preparation for the treatment of according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
74 parts of 74 parts of Radix Polygoni Multiflori of 74 parts of Cortexs Eucommiae of 74 parts of Radix Angelicae Pubescentiss of the Radix Astragali
62 parts of 62 parts of Radix panici repentics of 70 portions of Radix Gentianaes of 70 portions of Corm Eleocharitiss of Flos Sophorae
56 parts of 56 parts of Cyclocarya paliurus Iljinskaja of 56 parts of Radix Puerariaes of 62 parts of Radix Mori of Spica Prunellae
36 parts, 36 parts of Folium Nelumbinis of 46 parts of spirulinas of 46 parts of floral disc of sunflower of Fructus Hippophae.
3. a kind of hypertensive Chinese medicine preparation for the treatment of according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
66 parts of 66 parts of Radix Polygoni Multiflori of 66 parts of Cortexs Eucommiae of 66 parts of Radix Angelicae Pubescentiss of the Radix Astragali
54 parts of 54 parts of Radix panici repentics of 62 portions of Radix Gentianaes of 62 portions of Corm Eleocharitiss of Flos Sophorae
49 parts of 49 parts of Cyclocarya paliurus Iljinskaja of 49 parts of Radix Puerariaes of 54 parts of Radix Mori of Spica Prunellae
31 parts, 31 parts of Folium Nelumbinis of 40 parts of spirulinas of 40 parts of floral disc of sunflower of Fructus Hippophae.
4. a kind of hypertensive Chinese medicine preparation for the treatment of according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
58 parts of 58 parts of Radix Polygoni Multiflori of 58 parts of Cortexs Eucommiae of 58 parts of Radix Angelicae Pubescentiss of the Radix Astragali
48 parts of 48 parts of Radix panici repentics of 54 portions of Radix Gentianaes of 54 portions of Corm Eleocharitiss of Flos Sophorae
42 parts of 42 parts of Cyclocarya paliurus Iljinskaja of 42 parts of Radix Puerariaes of 48 parts of Radix Mori of Spica Prunellae
26 parts, 26 parts of Folium Nelumbinis of 34 parts of spirulinas of 34 parts of floral disc of sunflower of Fructus Hippophae.
5. as described in claim 1-4 any one, treat a preparation method for hypertensive Chinese medicine preparation, it is characterized in that: comprise following processing step:
(1) get the Radix Astragali, Radix Angelicae Pubescentis, the Cortex Eucommiae, Flos Sophorae, Radix panici repentics, Spica Prunellae, Cyclocarya paliurus Iljinskaja, Fructus Hippophae and spirulina and clean decontamination, put into container, the distilled water that adds 8-12 doubly to measure, soaked after 4-5 hour, boiled 3-4 hour, extracted; Again add 6-8 doubly to measure distilled water, boil 2-3 hour, extract; Finally add 4-6 doubly to measure distilled water, heated and boiled 1-2 hour, extracts; Merge three times extracting solution, filter, filtrate is condensed into the thick paste of relative density 1.10-1.15 at 60 ℃, drying under reduced pressure, standby;
(2) get Radix Polygoni Multiflori, Corm Eleocharitis and Radix Gentianae decontamination and clean, be placed in container and rub, taking juice is standby;
(3) get Radix Mori, Radix Puerariae and Folium Nelumbinis and clean decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 200 order fine powders, standby;
(4) get floral disc of sunflower and immerse 2-3 hour in the yellow wine that 3-4 doubly measures, take out, dry, grind into powder, cross 180 order fine powders, standby;
(5) above-mentioned steps (1)-(4) prepared thick paste, juice and powder are utilized to modern advanced pharmacy science and technology, make tablet, be the described hypertensive Chinese medicine preparation for the treatment of.
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