CN103520692B - A kind of preparation method for the treatment of the medicament of children's's suppurative tonsillitis - Google Patents
A kind of preparation method for the treatment of the medicament of children's's suppurative tonsillitis Download PDFInfo
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- CN103520692B CN103520692B CN201310500384.9A CN201310500384A CN103520692B CN 103520692 B CN103520692 B CN 103520692B CN 201310500384 A CN201310500384 A CN 201310500384A CN 103520692 B CN103520692 B CN 103520692B
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Abstract
The present invention relates to a kind of preparation method for the treatment of the medicament of children's's suppurative tonsillitis, the method comprises the following steps: to claim Herba Dracocephali Integrifolii 150 grams, Ocimum Basilicum 100 grams, Herba Solidaginis 100 grams, Radix Notoginseng 50 grams, Radix Saposhnikoviae 100 grams, Herba Pteridis creticae 50 grams, Rhizoma Zingiberis 50 grams, Rhizoma Dioscoreae 100 grams, Fructus Schisandrae Chinensis 50 grams, Semen Hyoscyami 150 grams, Radix Achyranthis Bidentatae 200 grams, Flos Rosae Chinensis 100 grams, Radix Et Rhizoma Nardostachyos 50 grams, Rhizoma Menispermi 150 grams and Rhizoma Curculiginis 50 grams, add 3500 milliliters, water, be placed in the flask of sealing, heat 5 hours under the water-bath of 80 DEG C, filter, collect filtrate and get final product.The medicament of the treatment children's suppurative tonsillitis that the method for the invention obtains has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect shows.
Description
The divisional application that the present invention's to be the applying date be December in 2012 6 days, application number are 201210534813.X, denomination of invention is " a kind of medicament for the treatment of children's's suppurative tonsillitis ".
Technical field
The present invention relates to otorhinolaryngology field, specifically, relate to a kind of medicament for the treatment of children's's suppurative tonsillitis.
Background technology
Acute suppurative tonsillitis is one of common infectious disease of child, is amygdaline samples inflammation.Common with the winter in spring of climate variability.Have that sickness rate is high, complication is many. relapse rate high.Serious threatens the healthy of child.Present children's mostly is only child, and the head of a family too spoils, therefore, in the urgent need to finding a kind of medicament for the treatment of children's's suppurative tonsillitis.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of children's's suppurative tonsillitis.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of children's's suppurative tonsillitis, it is made up of the material of following weight proportioning: Herba Dracocephali Integrifolii 10-20 part, Ocimum Basilicum 5-15 part, Herba Solidaginis 1-15 part, Radix Notoginseng 1-10 part, Radix Saposhnikoviae 1-15 part, Herba Pteridis creticae 1-10 part, Rhizoma Zingiberis 1-10 part, Rhizoma Dioscoreae 1-15 part, Fructus Schisandrae Chinensis 1-10 part, Semen Hyoscyami 10-20 part, Radix Achyranthis Bidentatae 10-30 part, Flos Rosae Chinensis 1-20 part, Radix Et Rhizoma Nardostachyos 1-10 part, Rhizoma Menispermi 10-20 part and Rhizoma Curculiginis 1-10 part.
Preferably, the medicament for the treatment of children's suppurative tonsillitis of the present invention is made up of the material of following weight proportioning: Herba Dracocephali Integrifolii 15 parts, Ocimum Basilicum 10 parts, Herba Solidaginis 10 parts, Radix Notoginseng 5 parts, Radix Saposhnikoviae 10 parts, Herba Pteridis creticae 5 parts, Rhizoma Zingiberis 5 parts, Rhizoma Dioscoreae 10 parts, Fructus Schisandrae Chinensis 5 parts, Semen Hyoscyami 15 parts, Radix Achyranthis Bidentatae 20 parts, Flos Rosae Chinensis 10 parts, Radix Et Rhizoma Nardostachyos 5 parts, Rhizoma Menispermi 15 parts and Rhizoma Curculiginis 5 parts.
Preferably, medicament of the present invention is tablet, buccal tablet, rapidly dissolving tablet or decoction.
The medicament for the treatment of children's suppurative tonsillitis of the present invention has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect shows.
Detailed description of the invention
Embodiment 1: the preparation of decoction of the present invention
Claim Herba Dracocephali Integrifolii 150 grams, Ocimum Basilicum 100 grams, Herba Solidaginis 100 grams, Radix Notoginseng 50 grams, Radix Saposhnikoviae 100 grams, Herba Pteridis creticae 50 grams, Rhizoma Zingiberis 50 grams, Rhizoma Dioscoreae 100 grams, Fructus Schisandrae Chinensis 50 grams, Semen Hyoscyami 150 grams, Radix Achyranthis Bidentatae 200 grams, Flos Rosae Chinensis 100 grams, Radix Et Rhizoma Nardostachyos 50 grams, Rhizoma Menispermi 150 grams and Rhizoma Curculiginis 50 grams, add 3500 milliliters, water, be placed in the flask of sealing, heat 5 hours under the water-bath of 80 DEG C, filter, collect filtrate and get final product.
Experimental example
90 routine infants all meet the diagnostic criteria (Huang Xuanzhao of involving acute suppurative tonsillitis in " otolaryngology-head and neck portion infectious disease ", Wang Gubao. practical otolaryngology [M]. Beijing: People's Health Publisher .1998,361-364).Treatment group 60 example, wherein man 38 example, female 22 example, 4.81 ± 1.29 years old mean age, average course of disease is (2.28 ± 0.97) d.Matched group 30 example, wherein man 19 example, female 11 example, 4.96 ± 1.24 years old mean age, average course of disease is (2.2 ± 0.96) d.Clinical manifestation: infant all has heating in various degree, pharyngalgia, dysphagia, tonsil has pus point or pus tongue.Wherein with large dry stool person 58 example, nasal obstruction watery nasal discharge person 23 example, food poor appetite person 36 example, the person of bringing up phlegm when one coughs 12 example, red tongue thick and greasy fur person 23 example.Tonsil II degree enlargement 62 example, tonsil III degree enlargement 28 example.Lab testing: Peripheral blood is as WBC < 10 × 10
9/ L is 15 examples, and WBC is 10 ~ 15 × 10
959 examples between/L, WBC is 16 ~ 20 × 10
916 examples between/L.Two groups of physical data, clinical manifestation, Peripheral blood picture, through statistical procedures there are no significant difference (P > 0.05), have comparability.
Decoction prepared by the oral embodiment 1 for the treatment of group, every twice-daily, treats 5 days by each 50 milliliters.Matched group adds quiet of penicillin 200,000 U/kg with 0.9% sodium chloride injection 150ml, every day 1 time.Penicillin anaphylaxis uses clindamycin 25mg/kg instead, every day 1 time, treats 5 days.
Criterion of therapeutical effect
With reference to " disease of tcm diagnoses and treatment standard " that State Administration of Traditional Chinese Medicine promulgates.Cure: pharyngalgia, heating paresthesia disappear, tonsil checks no pus point, without congested; Take a turn for the better: pharyngalgia and pharyngeal symptom obviously alleviate, on tonsil, pus point is eliminated; Invalid: bottleneck throat symptom is without significant change.
Therapeutic outcome
Treatment group cures 41 examples, and take a turn for the better 17 examples, invalid 2 examples, and total effective rate is 96.6%; Matched group cures 13 examples.Take a turn for the better 8 examples, no effect 9.Total effective rate is 70.0%.The successful for the treatment of group is better than the effect of matched group.The average fever time for the treatment of group and all comparatively matched group shortening of pharyngalgia improvement time.There is significant difference (P < 0.05).In table 1.
The improvement of table 12 groups of clinical symptoms, sign is compared
Note; Compare with matched group, Δ P < 0.05
Safety analysis
Do not occur serious adverse reaction in observation, treatment terminates the blood of rear treatment group and matched group patient, urine, stool routine and hepatic and renal function inspection and is showed no exception.
Claims (1)
1. treat the preparation method of the medicament of children's's suppurative tonsillitis for one kind, it is characterized in that: claim Herba Dracocephali Integrifolii 150 grams, Ocimum Basilicum 100 grams, Herba Solidaginis 100 grams, Radix Notoginseng 50 grams, Radix Saposhnikoviae 100 grams, Herba Pteridis creticae 50 grams, Rhizoma Zingiberis 50 grams, Rhizoma Dioscoreae 100 grams, Fructus Schisandrae Chinensis 50 grams, Semen Hyoscyami 150 grams, Radix Achyranthis Bidentatae 200 grams, Flos Rosae Chinensis 100 grams, Radix Et Rhizoma Nardostachyos 50 grams, Rhizoma Menispermi 150 grams and Rhizoma Curculiginis 50 grams, add 3500 milliliters, water, be placed in the flask of sealing, heat 5 hours under the water-bath of 80 DEG C, filter, collect filtrate and get final product.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210534813.XA CN102988948B (en) | 2012-12-06 | 2012-12-06 | Medicament for treating infantile suppurative tonsillitis |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210534813.XA Division CN102988948B (en) | 2012-12-06 | 2012-12-06 | Medicament for treating infantile suppurative tonsillitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103520692A CN103520692A (en) | 2014-01-22 |
| CN103520692B true CN103520692B (en) | 2015-08-05 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210534813.XA Expired - Fee Related CN102988948B (en) | 2012-12-06 | 2012-12-06 | Medicament for treating infantile suppurative tonsillitis |
| CN201310500384.9A Expired - Fee Related CN103520692B (en) | 2012-12-06 | 2012-12-06 | A kind of preparation method for the treatment of the medicament of children's's suppurative tonsillitis |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210534813.XA Expired - Fee Related CN102988948B (en) | 2012-12-06 | 2012-12-06 | Medicament for treating infantile suppurative tonsillitis |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104257749A (en) * | 2014-09-16 | 2015-01-07 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine composition for treating cold and preparation method of traditional Chinese medicine composition |
| CN104645059A (en) * | 2015-03-19 | 2015-05-27 | 许兰兰 | Medicine for treating infantile acute acute suppurative tonsillitis at infantile medicine center |
| CN104645058A (en) * | 2015-03-19 | 2015-05-27 | 许兰兰 | Medicament for treating children acute suppurative tonsillitis in paediatric internal medicine center |
| CN104983941A (en) * | 2015-08-10 | 2015-10-21 | 孙霞 | Traditional Chinese medicine for treating child suppurative tonsillitis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1475204A (en) * | 2002-06-30 | 2004-02-18 | 丛繁滋 | Medicinal Composition, dry powder vapor, nebula, nebula auxiliary preparation for use through mouth and nose and its preparation method |
| CN1572335A (en) * | 2003-05-04 | 2005-02-02 | 丛繁滋 | Self-Service respiratory vaccination instrument for SARS infectious disease |
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2012
- 2012-12-06 CN CN201210534813.XA patent/CN102988948B/en not_active Expired - Fee Related
- 2012-12-06 CN CN201310500384.9A patent/CN103520692B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN102988948B (en) | 2014-02-12 |
| CN103520692A (en) | 2014-01-22 |
| CN102988948A (en) | 2013-03-27 |
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