CN103520461A - Medicine for treating allergic rhinitis - Google Patents
Medicine for treating allergic rhinitis Download PDFInfo
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Abstract
The invention discloses medicine for treating allergic rhinitis, and belongs to the field of traditional Chinese medicine. The effective constituent of the medicine is composed of, by weight, 70 parts to 90 parts of saposhnicovia divaricata, 60 parts to 80 parts of medicine terminalia fruit, 55 parts to 75 parts of sea buckthorns, 50 parts to 70 parts of ipomoea pes-caprae, 45 parts to 60 parts of parthenocissus tricuspidata, 40 parts to 55 parts of glabrousleaf pittosporum roots, 35 parts to 50 parts of lily, 30 parts to 45 parts of herba rabdosiae, 25 parts to 43 parts of Artemisia japonica, 22 parts to 40 parts of felwort, 18 parts to 35 parts of fructus aurantii, 15 parts to 30 parts of tropic ageratum herbs, 12 parts to 25 parts of nauclea officinalis, 8 parts to 20 parts of dried earthworm, 5 parts to 16 parts of smoked plums and 3 parts to 12 parts of fructus xanthii. Selected medicine meets the requirement for the composing principles of herbal prescriptions, the medicine is applied according to pathogenesis, the medicine has the function of expelling wind and removing cold, the function of warming the lung and tonifying the kidney, the function of stopping nasal discharge, and the function of fortifying the spleen and disinhibiting the dampness, is good in absorption effect and obvious in curative effect, has no toxic and side effect and does not cause clinical adverse reaction, and the medicine is high in allergic rhinitis cure rate according to clinical verifications.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of medicine that is used for the treatment of allergic rhinitis.
Background technology
Allergic rhinitis is allergic rhinitis, refers to after atopic individuals contact allergen that mainly the medium by IgE discharges, and the non-infectious inflammatory diseases of nasal mucosa that has panimmunity competent cell and cytokine etc. to participate in.Allergic rhinitis pathological change is that telangiectasis, permeability increase and glandular secretion increase and eosinophilic granulocyte infiltration etc., the pathological change catabasis can recover normal, outbreak repeatedly, can cause that mucosal epithelium layer proliferative changes, cause mucosa plumpness and Polypoid changes, as concurrent infection, can show as glutinous pus tears or pus tears.
In clinical symptoms, allergic rhinitis shows as paroxysmal sneeze, clear water sample nasal mucus, intermittence or persistence nasal obstruction, the strong gargalesthesia of intranasal, while making a definite diagnosis, need determine and belong to intermittent allergic rhinitis or persistence allergic rhinitis, conventional Therapeutic Method can be selected pharmacotherapy, immunotherapy and surgical intervention according to individual specificity at present.Drug therapy can intranasal administration also can whole body administration, conventional oral or antihistaminic, glucocorticoid, anti-leukotriene medicine, color paulownia class medicine, intranasal Decongestant, intranasal anticholinergic for nose, and Chinese prescription; Immunization therapy is applicable to the situation that routine medication is invalid, adopts subcutaneous injection and sublingual administration, induces clinical and immunologic tolerance, may occur part and systemic adverse reactions; To having obvious anatomic variation with the special circumstances such as dysfunction, merging chronic rhinosinusitis coexisting-nasal polyp, applicable surgical operation therapy through medicine or immunization therapy without improvement, nasal cavity.
Traditional Chinese medical theory is thought, allergic rhinitis be by body defend that sun is solid, inhibited pulmonary QI, deficiency and cold of both the lung and kidney, kidney-yang deficiency, wind and cold invasions, deficiency of vital energy blood stagnation etc. cause a disease because of initiation, dialectical treating, when take expelling wind and cold, warming the lung the kidney invigorating, only sensible, the invigorating spleen to remove dampness of tears is purport, reasonable compatibility Chinese prescription, thus immunity of organisms, lung qi dispersing dampness removing improved, strengthen respiratory system function, reach the object for the treatment of of allergic rhinitis.
Summary of the invention
The invention provides a kind of medicine that is used for the treatment of allergic rhinitis, have expelling wind and cold, warming the lung the kidney invigorating, the effect of sensible, the invigorating spleen to remove dampness of tears only, cure the disease and ask source treating both the principal and secondary aspects of a disease, the allergic rhinitis that a variety of causes is caused all has good curative effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A medicine that is used for the treatment of allergic rhinitis, raw material composition and the parts by weight of making described effective ingredient are:
50～70 parts of 55～75 parts of Herba Ipomoeae Pes-Capraes of 60～80 portions of Fructus Hippophaes of 70～90 parts of terminalia flesh of Radix Saposhnikoviae
30～45 parts of 35～50 portions of Rabdosia rubescens of 40～55 portions of Bulbus Liliies of 45～60 parts of Radix Pittospori Glabratis of Radix seu Caulis Parthenocissi tricuspidatae
15～30 parts of 18～35 parts of Herba Agerati Conyzoidiss of 22～40 parts of Fructus Aurantiis of 25～43 portions of Radix Gentianaes of Herba Artemisiae Japonicae
3～12 parts of 5～16 portions of Fructus Xanthii of Lignum et Radix Naucleae 8～20 portions of Fructus Mumes of 12～25 parts of dry Pheretimas.
Raw material composition and the parts by weight of making described effective ingredient are:
60 parts of 65 parts of Herba Ipomoeae Pes-Capraes of 70 portions of Fructus Hippophaes of 80 parts of terminalia flesh of Radix Saposhnikoviae
38 parts of 43 portions of Rabdosia rubescens of 48 portions of Bulbus Liliies of 52 parts of Radix Pittospori Glabratis of Radix seu Caulis Parthenocissi tricuspidatae
23 parts of 26 parts of Herba Agerati Conyzoidiss of 30 parts of Fructus Aurantiis of 34 portions of Radix Gentianaes of Herba Artemisiae Japonicae
8 parts of 10 portions of Fructus Xanthii of Lignum et Radix Naucleae 14 portions of Fructus Mumes of 18 parts of dry Pheretimas.
A preparation method that is used for the treatment of the medicine of allergic rhinitis as described in claim 1-2 any one, comprises following processing step:
(1) terminalia flesh is fried with high heat to surface and is buff, after taking-up cools, pulverize and grind into powder in the lump with dry Pheretima, cross 120 order fine powders, standby;
(2) Radix seu Caulis Parthenocissi tricuspidatae, Bulbus Lilii are mixed thoroughly with Mel, slow fire is fried to surperficial glassy yellow and tack-free, after taking-up cools, grinds into powder, crosses 200 order fine powders, standby;
(3) Radix Saposhnikoviae, Fructus Hippophae, Herba Ipomoeae Pes-Capraes, Rabdosia rubescens, Herba Artemisiae Japonicae, Radix Gentianae, Herba Agerati Conyzoidis, Lignum et Radix Naucleae, Fructus Mume, Fructus Xanthii are put into container, add the water of octuple amount, boil rear immersion 8～10 hours, get and boil liquid; In remaining medicinal residues, add again the water of six times of amounts, boil rear immersion 6～8 hours, get and boil liquid; Merge twice gained and boil liquid, the thick paste that at 60 ℃ of heating evaporation simmer down tos, relative density is 1.10～1.15, standby;
(4) Radix Pittospori Glabrati, Fructus Aurantii are put into container, add the shao-hsing rice wine of four times of amounts, boil rear immersion 3～4 hours, get and boil liquid; In remaining medicinal residues, add again the shao-hsing rice wine of triplication, boil rear immersion 2～3 hours, get and boil liquid; Merge twice gained and boil liquid, the thick paste that at 60 ℃ of heating evaporation simmer down tos, relative density is 1.12～1.16, standby;
(5), by the fine powder of step (1), step (2) gained, with the thick paste mixing and stirring that step (3), step (4) make, quick-freezing Cheng Fenhou is prepared as tablet product.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Saposhnikoviae: acrid in the mouth, micro-sweet, slightly warm in nature; Return lung, bladder, liver, spleen channel.Deliver, dispel the wind, victory is wet, pain relieving.Cure mainly anemofrigid cold, headache, giddy, cold-damp stomachache, has loose bowels, rheumatic arthralgia, spasm of the limbs, tetanus, conjunctival congestion, skin infection, hernia abdominal mass, scabies, rubella." Japan hanako materia medica " carries: " invigorating middle warmer benefit god, blepharitis marginalis, arresting lacrimation and paralysis, tonneau the five internal organs GUAN-pulse, five kinds of strain and seven kinds of impairment, thin damage night sweat, vexed body weight, energy tranquilizing the mind, even gaseous pulse." modern medicine study confirmation, anti-wind energy significantly improves the hypoxia-bearing capability of acute cerebral hypoxia, significantly suppresses the formation of external lipid peroxide of bringing out, and has antioxidant activity, and neurocyte is shielded.
Terminalia flesh: bitter in the mouth, acid, puckery, property is flat; Enter lung, large intestine channel.Astringing intestine to stop diarrhea is astringed the lung, pathogenic fire reducing sore-throat relieving.Cure mainly chronic diarrhea chronic dysentery, the proctoptosis of having blood in stool, the deficiency of the lung is breathed with cough, and chronic cough is more than, pharyngalgia hoarseness." property of medicine opinion " carries: " sealing road, astringes the lung, five types of dysphagia knot for tonneau body fluid, main broken chest stagnation of QI." modern medicine study shows, terminalia flesh is rich in tannin, has the effect of convergence, antidiarrheal, and water decoction is effective to multiple dysentery bacterium, and remarkable to bacillus pyocyaneus, diphtheria corynebacterium effect, ethanol extract has antibacterial action, and smooth muscle is had to spasmolysis.
Fructus Hippophae: sour in the mouth, puckery, warm in nature.Eliminating phlegm and stopping cough, relieving dyspepsia, promoting blood circulation to remove blood stasis.For cough with copious phlegm, dyspepsia, abdominal pain due to retention of food, blood stasis amenorrhea, falls and flutters congestive edema.
Herba Ipomoeae Pes-Capraes: acrid in the mouth, micro-hardship, property is wet.Expelling wind and removing dampness, the detumescence of drawing out pus by applying a plaster to the affected part.For anemofrigid cold, rheumatic arthritis, lumbar muscle strain; Furuncle is controlled in external, hemorrhoid." Fujian traditional herbal medicine " carries: " eliminating carbuncle eliminating stagnation, expelling wind and removing dampness, Jiedu Yiqi.”
Radix seu Caulis Parthenocissi tricuspidatae: sweet in the mouth, warm in nature, return Liver Channel.Invigorate blood circulation, bent wind.Cure mainly blood stasis in puerperal, in abdomen, have piece, leucorrhea with red and white discharge, rheumatism bones and muscles pain, migraine, rheumatic arthralgia, apoplexy and hemiplegia, migraine and general headache, traumatic injury, carbuncle sore tumefacting virus, ulcer being unable to heal.
Radix Pittospori Glabrati: sweet in the mouth, hardship, cool in nature.Tonifying the lung kidney, wind-damp dispelling, promoting blood circulation to remove obstruction in the collateral.Cure mainly asthenia and breath with cough, seminal emission premature ejaculation, insomnia, dizziness, hypertension, rheumatic arthralgia, infantile paralysis.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " promoting blood circulation to remove obstruction in the collateral, relieving spasm to stop pain.Treating rheumatic arthritis, sciatica, injury and bone fracture, poliomyelitis sequela, puerperal paralysis, heart peratodynia, toothache.”
Bulbus Lilii: sweet in the mouth, micro-hardship, cold nature; Enter the heart, lung meridian.Nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.Cure mainly deficiency of YIN chronic cough, sputum mixed with blood, in the calentura later stage, waste heat is unclear, or the fidgets due to deficiency palpitation with fear of feelings will due to unsuccessful, insomnia and dreamful sleep, absentminded, carbuncle, eczema." Japan hanako materia medica " carries: " feel at ease, determine gallbladder, beneficial will, supports the five internal organs.Control insane heresy crow position, mad crying, palpitation with fear, kills diseases due to noxious agents produced by various parasites Qi ， Xie acute mastitis, carbuncle on the back and all skin ulcers swollen, and the mad fortune of blood after managing property." modern medicine study shows, Bulbus Lilii have significantly eliminate the phlegm, antitussive effect, to adrenal cortex function, exhaustion has significant protective effect, extends hypoxia endurance time, the effect that also has in addition calmness, nourishing YIN and moistening the lung, anticancer to breed.
Rabdosia rubescens: bitter in the mouth, sweet, cold nature.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.Main laryngopharynx swelling and pain, headache due to common cold, tracheitis, chronic hepatitis, rheumatic arthritis, snake bite and insect sting.Modern medicine study confirmation, this product Herb crude preparation by using is to esophagocardial carcinoma, hepatocarcinoma, and breast carcinoma, rectal cancer have certain mitigation, also can be used for preventing and treating radiocurable side reaction, acute, chronic pharyngitis, tonsillitis, parotitis, tracheitis, chronic persistent hepatitis etc.
Herba Artemisiae Japonicae: bitter in the mouth, sweet, property is flat.Heat clearing away, removing heat from blood, expelling summer-heat.For cold, fever, heatstroke, malaria, pulmonary tuberculosis hectic fever, hypertension; Wound hemorrhage is controlled in external, furuncle furuncle and phyma poison." Luchuan book on Chinese herbal medicine " carries: " wind dispelling is dispersed, and induces sweat and brings down a fever.The fever of the body that cures cold headache.”
Radix Gentianae: bitter in the mouth, cold in nature; Return liver, gallbladder meridian.Heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.For jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, persistent erection of the penis, eczema pruritus, conjunctival congestion, deafness, hypochondriac pain, bitter taste, convulsion with spasms." medicineization justice " carries: " fire of the special eliminating pathogen in the liver gallbladder of Radix Gentianae, cures mainly ophthalmalgia cervicodynia, pain in the hypochondrium, and infantile convulsion pathogen, infantile malnutrition, all genus Liver Channel pathogenic heats are for suffering from, wonderful with it.Its abnormal smells from the patient is thick and heavy and avale, kind clear damp-heat in lower-JIAO, if scroal abscess, inguinal bubo, primary sore, and urine is not smooth, also can remove gastric heat, flat ascarid, covers ascarid and obtains the bitter ear of pacifying.”
Fructus Aurantii: hardship, pungent, acid, temperature; Return spleen, stomach warp.Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention, gastroptosis, proctoptosis, uterine prolapse." Japan hanako materia medica " carries: " spleen benefiting and stimulating the appetite, adjusts the five internal organs, the therapeutic method to keep the adverse QI flowing downwards, and preventing or arresting vomiting is contrary, expectorant.Control regurgitation, cholera dysentery, helps digestion, broken crux mass beside the umbilicus, and five types of dysphagia, except wind improving eyesight and lung qi edema, sharp intestine and small intestine, skin is itched.Swollen can the processing of hemorrhoid pressed.”
Herba Agerati Conyzoidis: pungent, micro-hardship, cool.Expelling wind and clearing away heat, pain relieving, hemostasis, calculus.For upper respiratory tract infection, tonsillitis, pharyngolaryngitis, acute gastroenteritis, stomachache, stomachache, metrorrhagia, renal calculus, vesical calculus; Eczema is controlled in external, thrush, carbuncle pyogenic infections from tumour or sore, cellulitis, ulcer of the lower limb, otitis media, traumatic hemorrhage." Fujian traditional herbal medicine " carries: " eliminating carbuncle, removing blood stasis, removing toxic substances, parasite killing.Control lymphogranuloma inguinale inguinal bubo, muscles and bones spraining swollen and ache, throat moth.”
Lignum et Radix Naucleae: hardship, cold; Return lung, large intestine, gallbladder, urinary bladder channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain, for cold, fever, acute tonsillitis, pharyngolaryngitis, bronchitis, pneumonia, urinary system infection, enteritis, dysentery, cholecystitis; Mastitis are controlled in external, carbuncle furuncle abscess.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Treating acute tonsillitis, pharyngolaryngitis, mastitis, enteritis, bacillary dysentery, urinary tract infection, cholecystitis, ulcer of the lower limb, tinea pedis infects, furuncle and phyma pus infections, dermatitis and eczema.”
Dry Pheretima: salty in the mouth, cold in nature.Return liver, spleen, urinary bladder channel.Clear gesture relieving convulsion, suppressing the hyperactive liver to relieve the wind syndrome, dredge the meridian passage, the diuresis of relievining asthma.Cure mainly calentura heating mad dry, infantile convulsion is twitched, headache due to hyperactivity of liver-YANG, apoplectic hemiplegia, rheumatic arthralgia, dyspnea and cough due to lung-heat, urinary obstruction.Compendium of Material Medica is carried: " cold in nature and descending, cold in nature therefore can separate all hot diseases, descending former energy diuresis, control sufficient disease and the meridian dredging also.Main typhoid fever malaria, large fanatical tired, and children's's adult urinary obstruction, anxious chronic infantile convulsion, severe and migratory arthralgia pain." modern medicine study proves, dry Pheretima contains the compositions such as ground LONGSU, lumbrofebrin, vitamin B complex complex, has diuresis, eases pain, relievings asthma, the effect such as blood pressure lowering, analgesic, convulsion.
Fructus Mume: sour in the mouth, property is flat; Enter liver, spleen, lung, kidney, stomach, large intestine channel.Astringing lung-QI and relieving cough, relieving diarrhea with astringents, hemostasis, promotes the production of body fluid.Cure mainly chronic cough, deficiency-heat excessive thirst, chronic malaria, chronic diarrhea, dysentery, vomiting." detailed outline " carries: " astringing intestine to stop diarrhea of astringing the lung, controls chronic cough, dysentery, and regurgitation is dysphagic, ascariasis of biliary tract vomiting and diarrhea, detumescence, gushes expectorant, and parasite killing is separated ichthyotoxin, horse mump, sulfur poison." modern medicine study confirmation; Fructus Mume has obvious antibacterial action; dysentery bacterium, bacillus pyocyaneus, Bacillus typhi, escherichia coli, tubercule bacillus, Bacillus proteus, staphylococcus aureus, messy vibrio and various dermatophytes are all had to inhibitory action; and can stimulate the hormonal secretion of the parotid gland; and clearization blood, strengthens metabolic function.
Fructus Xanthii: bitter in the mouth, sweet, pungent, warm in nature, slightly poisonous; Return lung, Liver Channel.Dispersing wind and cold, clearing the nasal passage, wind-damp dispelling, antipruritic.Cure mainly nasal sinusitis, headche due to wind-cold, rheumatic arthralgia, rubella, eczema, scabies.Essentials of Matea Medica carries: " kind diaphoresis, loose rheumatism, upper logical brain top, descending sufficient knee joint, reaches skin outward.Control headache, order is dark, toothache, nasal sinusitis, deburring." modern medicine study shows, Fructus Xanthii has obvious antiinflammatory, antibacterial, blood sugar lowering and of short duration hypotensive effect, alleviates in addition in addition convulsions symptom, strengthens the effectiveness of respiratory function.
The present invention compared with prior art, has following beneficial effect:
The present invention selects medical material to meet a monarch and his subjects left side and makes it reason, for the cause of disease, suits the remedy to the case, and has expelling wind and cold, warming the lung the kidney invigorating, the effect of sensible, the invigorating spleen to remove dampness of tears only, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to allergic rhinitis cure rate through clinical verification.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
Radix Saposhnikoviae 80g terminalia flesh 70g Fructus Hippophae 65g Herba Ipomoeae Pes-Capraes 60g
Radix seu Caulis Parthenocissi tricuspidatae 52g Radix Pittospori Glabrati 48g Bulbus Lilii 43g Rabdosia rubescens 38g
Herba Artemisiae Japonicae 34g Radix Gentianae 30g Fructus Aurantii 26g Herba Agerati Conyzoidis 23g
The dry Pheretima 14g of Lignum et Radix Naucleae 18g Fructus Mume 10g Fructus Xanthii 8g.
The processing step of process for preparing medicine of the present invention is:
(1) terminalia flesh is fried with high heat to surface and is buff, after taking-up cools, pulverize and grind into powder in the lump with dry Pheretima, cross 120 order fine powders, standby;
(2) Radix seu Caulis Parthenocissi tricuspidatae, Bulbus Lilii are mixed thoroughly with Mel, slow fire is fried to surperficial glassy yellow and tack-free, after taking-up cools, grinds into powder, crosses 200 order fine powders, standby;
(3) Radix Saposhnikoviae, Fructus Hippophae, Herba Ipomoeae Pes-Capraes, Rabdosia rubescens, Herba Artemisiae Japonicae, Radix Gentianae, Herba Agerati Conyzoidis, Lignum et Radix Naucleae, Fructus Mume, Fructus Xanthii are put into container, add the water of octuple amount, boil rear immersion 8～10 hours, get and boil liquid; In remaining medicinal residues, add again the water of six times of amounts, boil rear immersion 6～8 hours, get and boil liquid; Merge twice gained and boil liquid, the thick paste that at 60 ℃ of heating evaporation simmer down tos, relative density is 1.10～1.15, standby;
(4) Radix Pittospori Glabrati, Fructus Aurantii are put into container, add the shao-hsing rice wine of four times of amounts, boil rear immersion 3～4 hours, get and boil liquid; In remaining medicinal residues, add again the shao-hsing rice wine of triplication, boil rear immersion 2～3 hours, get and boil liquid; Merge twice gained and boil liquid, the thick paste that at 60 ℃ of heating evaporation simmer down tos, relative density is 1.12～1.16, standby;
(5), by the fine powder of step (1), step (2) gained, with the thick paste mixing and stirring that step (3), step (4) make, quick-freezing Cheng Fenhou is prepared as tablet product.
Usage and dosage: adult every day 3 times, each 250～400mg, one hour after meal warm water delivery service, adds when serious symptom person has a stuffy nose once, and dosage 150mg 12 days is a course for the treatment of, and cure general 2～4 courses for the treatment of.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
Radix Saposhnikoviae 75g terminalia flesh 65g Fructus Hippophae 60g Herba Ipomoeae Pes-Capraes 55g
Radix seu Caulis Parthenocissi tricuspidatae 50g Radix Pittospori Glabrati 44g Bulbus Lilii 38g Rabdosia rubescens 35g
Herba Artemisiae Japonicae 31g Radix Gentianae 28g Fructus Aurantii 23g Herba Agerati Conyzoidis 19g
The dry Pheretima 10g of Lignum et Radix Naucleae 15g Fructus Mume 8g Fructus Xanthii 5g
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
The routine clinical observation of Allergic Rhinitis 80 of selecting Wo Yuanhuo outer court to make a definite diagnosis, patient is divided into two groups at random.Treatment group 40 examples, male's 23 examples wherein, women's 17 examples, 22～55 years old age, 42.6 years old mean age.Matched group 40 examples, male's 24 examples wherein, women's 16 examples, 19～57 years old age, 41.4 years old mean age.Two groups of qualifications and record of service are basically identical, without significant difference, have comparability.
2, treatment group patient takes medicine of the present invention, adult every day 3 times, and each oral 300mg, more than or tears of nasal obstruction tears stream and while not going out, add 150mg 1 time, 12 days are a course for the treatment of.Matched group gives antiallergic agent mist nasal cavity and sprays, and is aided with oral wide spectrum Claritin treatment.
3, efficacy determination:
(1) recovery from illness: paroxysmal sneeze stops, watery nasal discharge transference cure, nasal cavity is unobstructed, and gargalesthesia disappears.
(2) take a turn for the better: sneeze, thin nasal discharge, nasal obstruction, rhinocnesmus symptom alleviate or take a turn for the better.
(3) invalid: symptom is with treating front no significant difference.
4, result:
In treatment group, cure 27 examples, 9 examples that take a turn for the better, invalid 4 examples, cure rate 67.5%, total effective rate 90%.
In matched group, cure 8 examples, 11 examples that take a turn for the better, invalid 21 examples, cure rate 20%, total effective rate 47.5%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, old * *, man, 23 years old, student.Patient's readme, because attending a day school in school, gets up early winter, before 2 years, just suffered from allergic rhinitis, every day, WA minimumly will be made a call to more than 10 sneeze, rhinorrhea, all day is in a daze, easily sleepy, health is weak, sometimes also can have a headache, how many clinics have not been known for this reason, only see the doctor and buy medicine and just spent 10,000 polylith money, but loseing a bit improvement, having on the contrary the trend of deterioration.Medical because recently there is dizzy symptom ，Lai institute, be diagnosed as allergic rhinitis, advise it to take medicine of the present invention.Through following the tracks of inquiry, basic controlling rhinitis symptom after two courses for the treatment of, existing just taking the 3rd course for the treatment of.
2, Shen * *, female, 38 years old, teacher., after family finishing, there is rhinocnesmus, nasal obstruction, stream clear water nasal mucus before 3 years in patient's readme, sneeze, is allergic rhinitis to local hospital inspection, gives nose spray hormone therapy, poor effect.Before 2 years, start, outside rhinocnesmus, nasal obstruction, snivel, sneeze symptom, to occur pus nasal mucus, and flow backwards through the backward oral cavity of nose, breathe heavily night and suppress, developed into after diagnosing allergic asthma.Through taking medicine of the present invention after 3 courses for the treatment of, rhinocnesmus, nasal obstruction, thin nasal discharge, sneeze symptom are clearly better, and continue to take medicine of the present invention after 2 courses for the treatment of, and rhinitis symptom is almost recovered, accidental intermittent cough, on daily life without impact.
3, garden * *, man, 43 years old, office worker.Patient's readme is suffered from allergic rhinitis more than 4 years, and nasal obstruction, rhinorrhea, must madly sneeze battle array every morning and do repeatedly, and medication is failed to respond to any medical treatment really voluntarily, repeatedly show effect after 2 years, be still nasal mucus as clear water, seriously nasal obstruction, with headache symptom, and started to have slight asthma to occur, often in flu state.Nearly three days symptoms obviously increase the weight of ，Dao institute medical after, follow the doctor's advice and take medicine of the present invention, on normal dose basis, add once, after 3 courses for the treatment of, thin nasal discharge, nasal obstruction, headache symptom are obviously alleviated, in the middle of existing positive continued treatment.
Claims (3)
1. a medicine that is used for the treatment of allergic rhinitis, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
50～70 parts of 55～75 parts of Herba Ipomoeae Pes-Capraes of 60～80 portions of Fructus Hippophaes of 70～90 parts of terminalia flesh of Radix Saposhnikoviae
30～45 parts of 35～50 portions of Rabdosia rubescens of 40～55 portions of Bulbus Liliies of 45～60 parts of Radix Pittospori Glabratis of Radix seu Caulis Parthenocissi tricuspidatae
15～30 parts of 18～35 parts of Herba Agerati Conyzoidiss of 22～40 parts of Fructus Aurantiis of 25～43 portions of Radix Gentianaes of Herba Artemisiae Japonicae
3～12 parts of 5～16 portions of Fructus Xanthii of Lignum et Radix Naucleae 8～20 portions of Fructus Mumes of 12～25 parts of dry Pheretimas.
2. a kind of medicine that is used for the treatment of allergic rhinitis according to claim 1, is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
60 parts of 65 parts of Herba Ipomoeae Pes-Capraes of 70 portions of Fructus Hippophaes of 80 parts of terminalia flesh of Radix Saposhnikoviae
38 parts of 43 portions of Rabdosia rubescens of 48 portions of Bulbus Liliies of 52 parts of Radix Pittospori Glabratis of Radix seu Caulis Parthenocissi tricuspidatae
23 parts of 26 parts of Herba Agerati Conyzoidiss of 30 parts of Fructus Aurantiis of 34 portions of Radix Gentianaes of Herba Artemisiae Japonicae
8 parts of 10 portions of Fructus Xanthii of Lignum et Radix Naucleae 14 portions of Fructus Mumes of 18 parts of dry Pheretimas.
3. as described in claim 1-2 any one, be used for the treatment of a preparation method for the medicine of allergic rhinitis, it is characterized in that: comprise following processing step:
(1) terminalia flesh is fried with high heat to surface and is buff, after taking-up cools, pulverize and grind into powder in the lump with dry Pheretima, cross 120 order fine powders, standby;
(2) Radix seu Caulis Parthenocissi tricuspidatae, Bulbus Lilii are mixed thoroughly with Mel, slow fire is fried to surperficial glassy yellow and tack-free, after taking-up cools, grinds into powder, crosses 200 order fine powders, standby;
(3) Radix Saposhnikoviae, Fructus Hippophae, Herba Ipomoeae Pes-Capraes, Rabdosia rubescens, Herba Artemisiae Japonicae, Radix Gentianae, Herba Agerati Conyzoidis, Lignum et Radix Naucleae, Fructus Mume, Fructus Xanthii are put into container, add the water of octuple amount, boil rear immersion 8～10 hours, get and boil liquid; In remaining medicinal residues, add again the water of six times of amounts, boil rear immersion 6～8 hours, get and boil liquid; Merge twice gained and boil liquid, the thick paste that at 60 ℃ of heating evaporation simmer down tos, relative density is 1.10～1.15, standby;
(4) Radix Pittospori Glabrati, Fructus Aurantii are put into container, add the shao-hsing rice wine of four times of amounts, boil rear immersion 3～4 hours, get and boil liquid; In remaining medicinal residues, add again the shao-hsing rice wine of triplication, boil rear immersion 2～3 hours, get and boil liquid; Merge twice gained and boil liquid, the thick paste that at 60 ℃ of heating evaporation simmer down tos, relative density is 1.12～1.16, standby;
(5), by the fine powder of step (1), step (2) gained, with the thick paste mixing and stirring that step (3), step (4) make, quick-freezing Cheng Fenhou is prepared as tablet product.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104042863A (en) * | 2014-06-26 | 2014-09-17 | 刘义 | Externally-applied medicine patch capable of treating allergic rhinitis |
| CN104958605A (en) * | 2015-07-20 | 2015-10-07 | 济南舜景医药科技有限公司 | Traditional Chinese medicinal preparation for treating allergic rhinitis |
| CN105106590A (en) * | 2015-09-16 | 2015-12-02 | 于晓菲 | Medicine for treating allergic rhinitis |
| CN105125834A (en) * | 2015-08-31 | 2015-12-09 | 楼栋梁 | Drop for treating allergic rhinitis and preparation method of drop |
| CN105213761A (en) * | 2015-11-20 | 2016-01-06 | 王秀娟 | A kind of tablet and preparation method being used for the treatment of allergic rhinitis |
| CN107980718A (en) * | 2017-12-08 | 2018-05-04 | 合浦县浦乐牧业有限公司 | Improve live pig immunity and the cultural method of efficiency of feed utilization |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104042863A (en) * | 2014-06-26 | 2014-09-17 | 刘义 | Externally-applied medicine patch capable of treating allergic rhinitis |
| CN104958605A (en) * | 2015-07-20 | 2015-10-07 | 济南舜景医药科技有限公司 | Traditional Chinese medicinal preparation for treating allergic rhinitis |
| CN105125834A (en) * | 2015-08-31 | 2015-12-09 | 楼栋梁 | Drop for treating allergic rhinitis and preparation method of drop |
| CN105106590A (en) * | 2015-09-16 | 2015-12-02 | 于晓菲 | Medicine for treating allergic rhinitis |
| CN105213761A (en) * | 2015-11-20 | 2016-01-06 | 王秀娟 | A kind of tablet and preparation method being used for the treatment of allergic rhinitis |
| CN107980718A (en) * | 2017-12-08 | 2018-05-04 | 合浦县浦乐牧业有限公司 | Improve live pig immunity and the cultural method of efficiency of feed utilization |
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