CN103520411A - Medicine for treating facial paralysis - Google Patents
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Abstract
The invention provides a medicine for treating facial paralysis. Bulk drugs of the medicine comprise bile arisaema, isatis root, uncaria, balloonflower root, beautiful sweetgum fruit, small centipeda herb, stiff silkworm, gentian, yerbadetajo herb, milkvetch root, dodder seed, Chinese thorowax root, Sichuan lovage rhizome, saffron, incised notopterygium rhizome and root, largeleaf gentian root, Hypericum sampsonii Hance, dutchmanspipe vine, Radix Fici Hirtae, Cryptotaenia japonica Hassk and licorice. The medicine provided by the invention is cooperatively used with specified electromagnetic wave therapy, which enables a treatment effect on facial paralysis to be substantially improved and a good curative effect and fast action to be obtained.
Description
Technical field
The present invention relates to Chinese medicine technical field, relate in particular to a kind of Chinese powder medicine that is used for the treatment of facial paralysis.
Background technology
Facial paralysis is one of common clinical.It is many by virus or cold invasion and attack face nerve motor fiber that modern medicine is thought, make it that pathological changes occur and cause patient's side surface part mimetic musculature dyskinesia and occur that facial hemiparalysis is a kind of commonly encountered diseases of feature, also claim facial paralysis, facial neuritis, bell's palsy.
Gai Bingyi adolescence is common.Can betide any age, without significantly seasonal, person between twenty and fifty, postpartum women, weak old man, the young and the middle aged of suffering from cold after drinking, the poor child of resistance are the main invasion and attack objects of facial paralysis.Common clinical, if sequela is easily left in treatment not in time.Facial paralysis onset is hurried, take facial hemiparalysis as main clinical manifestation.Due to the particularity at disease damage position, the ill rear outward appearance that directly affects patient's face, has brought larger inconvenience to patient's daily life.
Modern medicine is thought, because bone facial pipe only can hold nervus facialis, passes through, once inflammatory edema occurs nervus facialis, must cause nervus facialis pressurized.Wind and cold, viral infection and autonomic nervous function are unstable etc. all can cause local nerve malnutrition, and vasospasm, causes neural ischemia edema.Modern medicine Therapeutic Method is more, mainly adopts Western medicine to alleviate nervus facialis edema, and alleviate nerve compression and promote neurological functional recovery, but unsatisfactory curative effect.
Motherland's medical science is thought, primary disease pathogenesis is become estranged for battalion defends, Wei Yang is solid, venation is hollow, heresy of wind and cold or wind heat invade sun bright with shaoyang channel arteries and veins, and cause,, blockage of main and collateral channels stagnant through vapour lock, muscles along the regular meridians lose and support, vertical slow receipts of muscle fallen ill, and control suitable harmonizing yingfen and weifen, expelling wind and clearing away heat, promoting blood circulation to remove obstruction in the collateral.
The present invention is exactly on the basis of this theory of Chinese medical science, proposes a kind of Chinese medicine that is used for the treatment of facial paralysis, and it coordinates specific electromagnetic wave treatment, can significantly improve the therapeutic effect of facial paralysis, good effect, instant effect.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine that is used for the treatment of facial paralysis, and it coordinates specific electromagnetic wave treatment, can significantly improve the therapeutic effect of facial paralysis, good effect, instant effect.
For solving the problems of the technologies described above, the invention provides and the invention provides a kind of Chinese medicine composition that is used for the treatment of facial paralysis, its crude drug comprises Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae, Herba Ecliptae, the Radix Astragali, Semen Cuscutae, Radix Bupleuri, Rhizoma Chuanxiong, Stigma Croci, Rhizoma Et Radix Notopterygii, Radix Gentianae Macrophyllae, Herba Hyperici Sampsonii, Herba Aristolochiae, Herba Fici Simplicissimae, Caulis et folium cryptotaeniae japonicae and Radix Glycyrrhizae.
Wherein, in described Chinese medicine composition, the weight of each crude drug is respectively:
Arisaema Cum Bile 50g～60g, Radix Isatidis 35g～45g, Ramulus Uncariae Cum Uncis 25g～35g, Radix Platycodonis 20g～30g, Fructus Liquidambaris 35g～45g, Herba Centipedae 25g～35g, Bombyx Batryticatus 15g～25g, Radix Gentianae 35g～45g, Herba Ecliptae 20g～30g, Radix Astragali 40g～50g, Semen Cuscutae 35g～45g, Radix Bupleuri 15g～25g, Rhizoma Chuanxiong 20g～30g, Stigma Croci 35g～45g, Rhizoma Et Radix Notopterygii 15g～25g, Radix Gentianae Macrophyllae 20g～30g, Herba Hyperici Sampsonii 30g～40g, Herba Aristolochiae 25g～35g, Herba Fici Simplicissimae 20g～30g, Caulis et folium cryptotaeniae japonicae 25g～35g and Radix Glycyrrhizae 35g～45g.
Wherein, in described Chinese medicine composition, the weight of each crude drug is respectively:
Arisaema Cum Bile 55g, Radix Isatidis 40g, Ramulus Uncariae Cum Uncis 30g, Radix Platycodonis 25g, Fructus Liquidambaris 40g, Herba Centipedae 30g, Bombyx Batryticatus 20g, Radix Gentianae 40g, Herba Ecliptae 25g, Radix Astragali 45g, Semen Cuscutae 40g, Radix Bupleuri 20g, Rhizoma Chuanxiong 25g, Stigma Croci 40g, Rhizoma Et Radix Notopterygii 20g, Radix Gentianae Macrophyllae 25g, Herba Hyperici Sampsonii 35g, Herba Aristolochiae 30g, Herba Fici Simplicissimae 25g, Caulis et folium cryptotaeniae japonicae 30g and Radix Glycyrrhizae 40g.
The present invention also provides the preparation method of above-mentioned Chinese medicine composition, and it is specially:
The first step, Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae are ground into respectively to coarse powder, according to above-mentioned weight, mix, in mixture: the even moistening of ethanol mass ratio=1:1 ratio of determining alcohol 80%, airtight placement more than 10 hours, drops in percolate pot, floods 24 hours, percolation, percolate flow velocity 95～105L per hour; By this speed, constantly add determining alcohol is 80% ethanol simultaneously, in percolation process, keeps ethanol to be not less than powder, collect percolate and be medical material amount 8 times, merge percolate, and concentrating under reduced pressure is removed ethanol, obtains and gets dry extract, and is ground into the first powder;
Second step, is ground into respectively coarse powder by remaining component, according to above-mentioned weight, mixes, and decocts with water twice, adds for the first time 10 times of water gagings, decocts two hours, filters; Add for the second time 8 times of water gagings, decoct two hours, filter; Merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder;
The 3rd step, mixes the first powder and the second powder, forms described Chinese medicine composition.
The present invention also provides a kind of Chinese medicine composition composition powders that is used for the treatment of facial paralysis, and its crude drug comprises Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae, Herba Ecliptae, the Radix Astragali, Semen Cuscutae, Radix Bupleuri, Rhizoma Chuanxiong, Stigma Croci, Rhizoma Et Radix Notopterygii, Radix Gentianae Macrophyllae, Herba Hyperici Sampsonii, Herba Aristolochiae, Herba Fici Simplicissimae, Caulis et folium cryptotaeniae japonicae and Radix Glycyrrhizae;
The preparation method of described Chinese medicine composition composition powders is specially,
The first step, Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae are ground into respectively to coarse powder, according to above-mentioned weight, mix, in mixture: the even moistening of ethanol mass ratio=1:1 ratio of determining alcohol 80%, airtight placement more than 10 hours, drops in percolate pot, floods 24 hours, percolation, percolate flow velocity 95～105L per hour; By this speed, constantly add determining alcohol is 80% ethanol simultaneously, in percolation process, keeps ethanol to be not less than powder, collect percolate and be medical material amount 8 times, merge percolate, and concentrating under reduced pressure is removed ethanol, obtains and gets dry extract, and is ground into the first powder;
Second step, is ground into respectively coarse powder by remaining component, according to above-mentioned weight, mixes, and decocts with water twice, adds for the first time 10 times of water gagings, decocts two hours, filters; Add for the second time 8 times of water gagings, decoct two hours, filter; Merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder;
The 3rd step, mixes the first powder and the second powder, forms described Chinese medicine composition composition powders.
The present invention also provides the using method of above-mentioned Chinese medicine composition, in described Chinese medicine composition composition powders, add a small amount of water, with alcohol burner, heat and stir and become pasty state, treat that mass is slightly cool, get sterile gauze piece, mass is coated on gauze piece, at patient's yang white, the sun, dicang, cheek car with Quan Liao cave sticks 30min.
Beneficial effect of the present invention:
The Chinese medicine that is used for the treatment of facial paralysis provided by the invention, it coordinates specific electromagnetic wave treatment, can significantly improve the therapeutic effect of facial paralysis, good effect, instant effect.
The specific embodiment
Facial paralysis belongs to the traditional Chinese medical science " apoplexy " category, and its pathogenesis is the positive QI-insufficiency of body, and ailment said due to cold or exposure is taken advantage of a weak point in opponent's defence into apoplex involving the channels and collaterals, and priming expectorant is turbid, and that wind-phlegm hinders is bright in sun, few sun, sun meridians, therefore see facial hemiparalysis, dysphonia, eyelid can not be closed.Motherland's medical science thinks, facial paralysis is due to the positive QI-insufficiency of body, and face venation is hollow, and pathogen is attacked in an opponent's defence facial venation, numbness air resister, muscle arteries and veins and lost and support, vertical slow receipts of facial muscle and causing.
The pathogeny of primary disease mainly due to healthy energy element a little less than, QI and blood is popular not smooth, causes a facial lateral vein network hollow, Wei Yang is solid, protect table function low, and wind-engaging causes.Wind has exogenous wind endogenous wind not.And wind being the primary exopathogen, many double its heresies of holding under the arm, as wind and cold, wind heat, rheumatism, wind-phlegm blood stasis etc., the muscles along the regular meridians venation of bright, the few sun of invasion and attack sun, a sun and side surface part disharmony between QI and blood occurs, channels loses supports, cause and of flaccid musclesly do not receive that facial both sides channels disequilibrium causes that disease side face muscle is askew forms facial hemiparalysis to strong side.
TDP is specific electromagnetic wave, can match with human biological electricity wavelength and produces resonance, regulates in immunologic function and enhanced biological " self-regulation system ", plays the effect of inflammation-inhibiting, analgesia, raising immunity of organisms.The infrared-ray that TDP lamp sends can improve local blood circulation, promotes inflammation and local edema to disappear, and accelerates repair of damaged tissues.And nebula wind scoop place is equivalent to the body surface inner projection point of stylomastoid foramen, under cave, there is nervus facialis outlet etc., with improving local blood circulation and lymph circulation in this region of TDP light irradiation, facial paralysis is alleviated.
The present invention adopts Chinese powder medicine to coordinate TDP facial paralysis, is the combined effect by heating power and medicine, by skin expansion tiny blood vessels, accelerates blood circulation, from outward appearance to inner essence, and in warm middle enforcement treatment.So directly dredge facial meridians by Chinese medicine and Re Ke, promote regional flow, improve blood and supply and nutrition, make to ooze out minimizing, absorption of edema, thus reach therapeutic purposes.
Based on this, the invention provides a kind of Chinese medicine composition that is used for the treatment of facial paralysis, its crude drug comprises Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae, Herba Ecliptae, the Radix Astragali, Semen Cuscutae, Radix Bupleuri, Rhizoma Chuanxiong, Stigma Croci, Rhizoma Et Radix Notopterygii, Radix Gentianae Macrophyllae, Herba Hyperici Sampsonii, Herba Aristolochiae, Herba Fici Simplicissimae, Caulis et folium cryptotaeniae japonicae and Radix Glycyrrhizae.
Further, described Chinese medicine composition only consists of above-mentioned raw materials medicine.
In described Chinese medicine composition, the weight of each crude drug is respectively:
Arisaema Cum Bile 50g～60g, Radix Isatidis 35g～45g, Ramulus Uncariae Cum Uncis 25g～35g, Radix Platycodonis 20g～30g, Fructus Liquidambaris 35g～45g, Herba Centipedae 25g～35g, Bombyx Batryticatus 15g～25g, Radix Gentianae 35g～45g, Herba Ecliptae 20g～30g, Radix Astragali 40g～50g, Semen Cuscutae 35g～45g, Radix Bupleuri 15g～25g, Rhizoma Chuanxiong 20g～30g, Stigma Croci 35g～45g, Rhizoma Et Radix Notopterygii 15g～25g, Radix Gentianae Macrophyllae 20g～30g, Herba Hyperici Sampsonii 30g～40g, Herba Aristolochiae 25g～35g, Herba Fici Simplicissimae 20g～30g, Caulis et folium cryptotaeniae japonicae 25g～35g and Radix Glycyrrhizae 35g～45g.
In described Chinese medicine composition, the weight of each crude drug is respectively:
Arisaema Cum Bile 55g, Radix Isatidis 40g, Ramulus Uncariae Cum Uncis 30g, Radix Platycodonis 25g, Fructus Liquidambaris 40g, Herba Centipedae 30g, Bombyx Batryticatus 20g, Radix Gentianae 40g, Herba Ecliptae 25g, Radix Astragali 45g, Semen Cuscutae 40g, Radix Bupleuri 20g, Rhizoma Chuanxiong 25g, Stigma Croci 40g, Rhizoma Et Radix Notopterygii 20g, Radix Gentianae Macrophyllae 25g, Herba Hyperici Sampsonii 35g, Herba Aristolochiae 30g, Herba Fici Simplicissimae 25g, Caulis et folium cryptotaeniae japonicae 30g and Radix Glycyrrhizae 40g.
Each crude drug pharmacology is as follows:
Arisaema Cum Bile: bitter in the mouth, micro-pungent, cool in nature, return lung, liver, spleen channel, there is removing heat-phlegm, the effect of dispelling wind and relieving convulsion, for phlegm-heat cough, coughs up phlegm yellow thick, middle wind-phlegm fan, the cards such as demented infantile convulsion.
Radix Isatidis: bitter in the mouth, cold in nature, enter the heart, liver, gallbladder, stomach warp, there is the effect of heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving, be used for the treatment of maculae caused by violent heat pathogen; High heat headache; Major part pestilence; Crimson tongue is purple dark, scarlet fever; Erysipelas; Mumps; Sore throat; Skin ulcer is swollen, carbuncle; Chickenpox; Measles; Hepatitis; Influenza, epidemic encephalitis, encephalitis b, pneumonia, coma is told nosebleed, pharyngeal swelling, acute catarrhal conjunctivitis, the cards such as skin ulcer rash.
Ramulus Uncariae Cum Uncis: sweet in the mouth, slightly warm in nature, enters Liver Channel, has the effect of heat clearing away, suppressing the hyperactive liver and subsiding YANG, relieving spasm by subduing liver-wind, is mainly used in the spasm due to the anxious raw wind of heat or liver-wind stirring up internally, twitch, restlessness, excessive rising of liver-YANG or Liver Channel have the headache of heat dizzy, the symptoms such as conjunctival congestion and swelling pain.
Radix Platycodonis: bitter in the mouth, pungent, property is flat, returns lung meridian, has lung qi dispersing, sore-throat relieving, eliminates the phlegm, the effect of evacuation of pus, cures mainly cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia hoarseness, the cards such as lung abscess vomiting pus.
Fructus Liquidambaris: bitter in the mouth, property is flat, returns liver, and kidney channel, has dispelling, collateral-activating, the effect that diuretic stimulates the menstrual flow, for arthralgia, numbness contracture, edema distension, the cards such as the few amenorrhea of breast.
Herba Centipedae: latin name Centipedae Hebra, acrid in the mouth, warm in nature, enter lung, Liver Channel, there is cold-dispelling, clearing the nasal passage, eliminating phlegm and stopping cough, the effect of dissipating blood stasis for subsidence of swelling, for exterior syndrome due to wind-cold, nasal obstruction watery nasal discharge and nasal sinusitis, cough with copious phlegm, pertussis, the cards such as sore, carbuncle and painful swelling.
Bombyx Batryticatus: acrid in the mouth, one-tenth, property is flat, returns liver, lung, stomach warp, has expelling wind to relieve convulsion, dissipating phlegm and resolving masses, the effect of heat-clearing and toxic substances removing dampness, cures mainly convulsion with spasms, laryngopharynx swelling and pain, submandibular lymph nodes is scorching, facial paralysis, the cards such as skin pruritus.
Radix Gentianae: bitter in the mouth, cold in nature, enter liver, gallbladder meridian, there is heat clearing and damp drying, fall the effect of letting out liver-fire and function of gallbladder promoting, the breast side of body being mainly used in due to dampness-heat of the liver is had a pain, and bitter taste is deaf, conjunctival congestion and swelling pain; Jaundice due to damp-heat; The dizzy order of flaming up of liver-fire is swollen; The high heat of liver-fire wind-transformation is through taking out; The cards such as the leucorrhea of damp invasion of lower energizer, dysuria.
Herba Ecliptae: sweet in the mouth, acid, cold in nature, return liver, kidney channel, play liver and kidney tonifying, the effect of cooling blood for hemostasis, for having a dizzy spell due to the hepatic and renal YIN deficiency, blurring of vision, soreness of the waist and knees; Be suitable for the deficiency of YIN and have hot person, be used for the treatment of the haematemesis of accumulated heat in stomach, the symptoms such as the hemoptysis of injury of blood vessel of the lung by heat, Herba Ecliptae has inhibitory action to staphylococcus aureus, Bacillus typhi, Song's Shigella flexneri, bacillus pyocyaneus, obviously enhancing non-specific immunity and cellular immune function.
The Radix Astragali: sweet in the mouth, warm in nature, enter spleen, lung meridian, there is tonification spleen soil, elevate a turnable ladder yang-energy, strengthening superficial resistance to stop perspiration, the effects such as holder skin ulcer granulation promoting, are mainly used in the weak anorexia and loose stool due to deficiency of both the splenic and pulmonary QI, shortness of breath and palpitation, the visceroptosis of sinking of QI of middle-JIAO, the metrorrhagia of QI failing to control blood is had blood in stool, chronic diarrhea proctoptosis; The spontaneous sweating of exterior deficiency, the cards such as insufficiency of vital energy and blood, the Radix Astragali strengthens heart contraction ability, can improve the blood circulation of whole body, can coronary artery dilator, kidney blood vessel and Rhizoma Bistortae peripheral vessel, make cutaneous circulation vigorous; Can improve the nonspecific immunity power of body, protect the liver and fall hypoglycemic effect, staphylococcus, blood dissolubility streptococcus, Diplococcus pneumoniae, dysentery bacterium etc. are had to inhibitory action.
Semen Cuscutae: sweet in the mouth, pungent, property is flat, enters liver,kidney,spleen warp, have the kidney invigorating and essence nourishing, the effect of nourishing the liver to improve visual acuity, cures mainly the sexual impotence of insufficiency of kidney-YANG, seminal emission premature ejaculation, frequent micturition, dizziness and tinnitus, the pain in the lumbar region of suffering from a deficiency of the kidney, married woman's leukorrhagia, not admittedly, the binocular of both liver and kidney deficiency, deficiency of liver-blood is dim-sighted, blurring of vision for nausea, the loose stool stomachache of asthenia of both the spleen and kidney, the cards such as aqueous-grainy diarrhea.
Radix Bupleuri: bitter in the mouth, cold nature, returns Liver Channel, gallbladder meridian, have evacuate bring down a fever, the effect of yang invigorating soothing liver-QI, for cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, the card such as uterus comes off, menoxenia.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature, return liver, gallbladder, pericardium channel, there is blood-activating and qi-promoting, the effect of wind-expelling pain-stopping, cures mainly menoxenia; Amenorrhea dysmenorrhea; The stagnant raw meat pain of the stasis of blood in puerperal; Lump in the abdomen lump; Pain in chest and hypochondrium; Have a headache dizzy; Anemofrigid-damp arthralgia; Traumatic injury; The cards such as ulcer sores.
Stigma Croci: sweet in the mouth, property is flat, energy blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens, pain relieving.Be used for the treatment of troubled thoughts pent-up, chest and diaphragm painful abdominal mass is vexed, spits blood, and typhoid fever is gone mad, frightened fear in a trance, women's amenorrhea, and stasis menoxenia, prolonged lochia, blood stasis is had a pain, measles, the cards such as traumatic injury.
Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature, enter kidney, urinary bladder channel, there is the effect of the cold expelling that induces sweat, expelling wind and dampness, pain relieving, there is the wet exterior syndrome of wind and cold folder, disease is seen fever with aversion to cold, headache as is wrapped up in, neck rigid back pain, the card such as limbs are heavy, and joint is ached, anemofrigid-damp arthralgia.
Radix Gentianae Macrophyllae: latin name Gentianae Macrophyllae Radix, acrid in the mouth, hardship, cold nature, returns stomach warp, Liver Channel, gallbladder meridian, there is wind-damp dispelling, relaxing muscles and tendons network, the effect of clearind deficient heat, cures mainly rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, afternoon fever, the cards such as infantile malnutrition heating.
Herba Hyperici Sampsonii: bitter in the mouth, pungent, cold in nature, return liver, spleen channel, there is removing pathogenic heat from blood and toxic substance from the body, promoting blood flow to regulate menstruation, the effect of dispelling wind and removing obstruction in the collateral, cure mainly various hemorrhage, enteritis and dysentery, acute mastitis, carbuncle furunculosis, scalds, venom, menoxenia, dysmenorrhea, leucorrhea, traumatic injury, rheumatic arthralgia, the cards such as aphtha.
Herba Aristolochiae: latin name Herba Aristolochiae, bitter in the mouth; Warm in nature, return liver, spleen, kidney channel, has circulation of qi promoting removing dampness, and the effect of promoting blood circulation and stopping pain, cures mainly stomachache, colicky, edema during pregnancy, puerperal, vim and vigour were suffered from abdominal pain, rheumatalgia.Promoting flow of QI and blood, pain relieving, diuresis.Edema during pregnancy, breast stomachache, colic, the cards such as rheumatalgia.
Herba Fici Simplicissimae: sweet, tepor, has invigorating the spleen for eliminating dampness, promoting the circulation of QI and reducing phlegm, the effect of relaxing muscles and tendons and activating QI and blood in the collateral, cures mainly pulmonary tuberculosis cough, chronic bronchitis, rheumatic arthritis, lumbago and skelalgia, insufficiency of the spleen edema, the after being ill card such as night sweat.
Caulis et folium cryptotaeniae japonicae: acrid in the mouth, hardship; Property is put down, and has dispelling wind stopping cough; Eliminating damp, detoxifying; The effect of blood-activating analgetic, cures mainly pneumonia, pulmonary abscess, and gonorrhea, hernia, acute toothache, carbuncle furuncle is swollen, herpes zoster, the cards such as skin pruritus.
The present invention also provides the preparation method of above-mentioned Chinese medicine composition composition powders, and it is specially:
The first step, Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae are ground into respectively to coarse powder, according to above-mentioned weight, mix, in mixture: the even moistening of ethanol mass ratio=1:1 ratio of determining alcohol 80%, airtight placement more than 10 hours, drops in percolate pot, floods 24 hours, percolation, percolate flow velocity 95～105L per hour; By this speed, constantly add determining alcohol is 80% ethanol simultaneously, in percolation process, keeps ethanol to be not less than powder, collect percolate and be medical material amount 8 times, merge percolate, and concentrating under reduced pressure is removed ethanol, obtains and gets dry extract, and is ground into the first powder;
Second step, is ground into respectively coarse powder by remaining component, according to above-mentioned weight, mixes, and decocts with water twice, adds for the first time 10 times of water gagings, decocts two hours, filters; Add for the second time 8 times of water gagings, decoct two hours, filter; Merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder;
The 3rd step, mixes the first powder and the second powder, forms described Chinese medicine composition composition powders.
The present invention also provides the using method of above-mentioned Chinese medicine composition, in described Chinese medicine composition composition powders, add a small amount of water, with alcohol burner, heat and stir and become pasty state, treat that mass is slightly cool, get sterile gauze piece, mass is coated on gauze piece, at patient's yang white, the sun, dicang, cheek car with Quan Liao cave sticks 30min.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese medicine composition composition powders 1
Arisaema Cum Bile 55g, Radix Isatidis 40g, Ramulus Uncariae Cum Uncis 30g, Radix Platycodonis 25g, Fructus Liquidambaris 40g, Herba Centipedae 30g, Bombyx Batryticatus 20g, Radix Gentianae 40g are ground into respectively to coarse powder, mix, in mixture: the even moistening of ethanol mass ratio=1:1 ratio of determining alcohol 80%, airtight placement is more than 10 hours, drop in percolate pot, flood percolation, percolate flow velocity 95L per hour 24 hours, by this speed, constantly add determining alcohol is 80% ethanol simultaneously, in percolation process, keep ethanol to be not less than powder, collection percolate is 8 times of medical material amount, merge percolate, concentrating under reduced pressure is removed ethanol, obtain and get dry extract, be ground into the first powder, by Herba Ecliptae 25g, Radix Astragali 45g, Semen Cuscutae 40g, Radix Bupleuri 20g, Rhizoma Chuanxiong 25g, Stigma Croci 40g, Rhizoma Et Radix Notopterygii 20g, Radix Gentianae Macrophyllae 25g, Herba Hyperici Sampsonii 35g, Herba Aristolochiae 30g, Herba Fici Simplicissimae 25g, Caulis et folium cryptotaeniae japonicae 30g and Radix Glycyrrhizae 40g are ground into respectively coarse powder, mix, decoct with water twice, add for the first time 10 times of water gagings, decoct two hours, filter, add for the second time 8 times of water gagings, decoct two hours, filter, merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder, and the first powder and the second powder are mixed, and forms described Chinese medicine composition composition powders 1.
Embodiment 2 Chinese medicine composition composition powders 2
Arisaema Cum Bile 50g, Radix Isatidis 35g, Ramulus Uncariae Cum Uncis 25g, Radix Platycodonis 20g, Fructus Liquidambaris 35g, Herba Centipedae 25g, Bombyx Batryticatus 15g, Radix Gentianae 35g are ground into respectively to coarse powder, mix, in mixture: the even moistening of ethanol mass ratio=1:1 ratio of determining alcohol 80%, airtight placement is more than 10 hours, drop in percolate pot, flood percolation, percolate flow velocity 95L per hour 24 hours, by this speed, constantly add determining alcohol is 80% ethanol simultaneously, in percolation process, keep ethanol to be not less than powder, collection percolate is 8 times of medical material amount, merge percolate, concentrating under reduced pressure is removed ethanol, obtain and get dry extract, be ground into the first powder, by Herba Ecliptae 20g, Radix Astragali 40g, Semen Cuscutae 35g, Radix Bupleuri 15g, Rhizoma Chuanxiong 20g, Stigma Croci 35g, Rhizoma Et Radix Notopterygii 15g, Radix Gentianae Macrophyllae 20g, Herba Hyperici Sampsonii 30g, Herba Aristolochiae 25g, Herba Fici Simplicissimae 20g, Caulis et folium cryptotaeniae japonicae 25g and Radix Glycyrrhizae 35g are ground into respectively coarse powder, mix, decoct with water twice, add for the first time 10 times of water gagings, decoct two hours, filter, add for the second time 8 times of water gagings, decoct two hours, filter, merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder, and the first powder and the second powder are mixed, and forms described Chinese medicine composition composition powders 2.
Embodiment 3
Arisaema Cum Bile 60g, Radix Isatidis 45g, Ramulus Uncariae Cum Uncis 35g, Radix Platycodonis 30g, Fructus Liquidambaris 45g, Herba Centipedae 35g, Bombyx Batryticatus 25g, Radix Gentianae 45g are ground into respectively to coarse powder, mix, in mixture: the even moistening of ethanol mass ratio=1:1 ratio of determining alcohol 80%, airtight placement is more than 10 hours, drop in percolate pot, flood percolation, percolate flow velocity 95L per hour 24 hours, by this speed, constantly add determining alcohol is 80% ethanol simultaneously, in percolation process, keep ethanol to be not less than powder, collection percolate is 8 times of medical material amount, merge percolate, concentrating under reduced pressure is removed ethanol, obtain and get dry extract, be ground into the first powder, by Herba Ecliptae 30g, Radix Astragali 50g, Semen Cuscutae 45g, Radix Bupleuri 25g, Rhizoma Chuanxiong 30g, Stigma Croci 45g, Rhizoma Et Radix Notopterygii 25g, Radix Gentianae Macrophyllae 30g, Herba Hyperici Sampsonii 40g, Herba Aristolochiae 35g, Herba Fici Simplicissimae 30g, Caulis et folium cryptotaeniae japonicae 35g and Radix Glycyrrhizae 45g are ground into respectively coarse powder, mix, decoct with water twice, add for the first time 10 times of water gagings, decoct two hours, filter, add for the second time 8 times of water gagings, decoct two hours, filter, merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder, and the first powder and the second powder are mixed, and forms described Chinese medicine composition composition powders 3.
Clinical data
Patient comes from December, 2007 to 2013 year March, totally 162 examples, wherein, man's 82 examples, female's 80 examples, 16～73 years old age, 7 days～6 months 97 examples of the course of disease, 6 months～1 year 65 examples, left side facial paralysis 87 examples, right side facial paralysis 75 examples, be divided into 3 groups, be respectively treatment group 62 examples, contrast 1 group of 50 example and contrast 2 group of 50 example.
Diagnostic criteria is with reference to national higher medical institution teaching material " neural medicine ", " subject of acupuncture and moxibustion theraphy ".Facial paralysis due to eliminating parotitis, otitis media, tumor, wound, cerebral hemorrhage, cerebral infarction, oncothlipsis etc.Clinical manifestation is sudden onset, and a side surface part is stiff, numb, lax, can not make wrinkle volume, closes order, rouse the actions such as cheek, bicker slants tiltedly to strong, and sick side sleeping with eyes half-closed is shed tears, and volume stricture of vagina disappears or shoals, during feed, food debris is often stranded in the tooth buccal space of disease side, and often has saliva to flow out.Or from the beginning of after having ear or under ear or under ear and face ache, or front 2/3 hypogeusia of Ipsilateral tongue or disappearance, even hyperacusis etc.
Therapeutic Method
Treatment group: will add a small amount of water in the powder 1 of embodiment 1 preparation, with alcohol burner, heat and stir and become pasty state, treat that mass is slightly cool, get sterile gauze piece, mass is coated on gauze piece, at patient's yang white, the sun, dicang, cheek car with Quan Liao cave sticks 30min, adopt TDP light irradiation simultaneously: with TDP irradiate Ipsilateral Wangue, nebula wind to just leading, cheek car region, continue 30min every day 1 time at every turn, be for 10 times a course for the treatment of, have a rest and carry out next course for the treatment of after 1 day, totally 2 courses for the treatment of.
Contrast 1 group: adopt BT-701-1B electrical stunning device, dilatational wave, electro acupuncture yang white, the sun, dicang, cheek car He Quan Liao cave, simultaneously with TDP irradiate Ipsilateral Wangue, nebula wind to just leading, cheek car region, each continue 30min every day 1 time, 10 times is a course for the treatment of, carries out next course for the treatment of, totally 2 courses for the treatment of after having a rest 1 day.
Contrast 2 groups: doctor trained in Western medicine conventional therapy: 1. glucocorticoid application: prednisone (20～30mg) or dexamethasone (1.5～3.0mg) 1/d, oral, continuous 7～10d; 2. use vasodilation to improve microcirculation, alleviate edema, 706 plasma substitutes or low molecular dextran 250～500mL, quiet 1 time/d, continuous 7～10d; 3. the application of neurotrophy metabolic drug: vitamin B
150～100mg, vitamin B
12100 μ g, citicoline 250mg, ubiquinone
105～10mg etc., intramuscular injection 1d1 time; 4. coordinate the local physical therapys such as infrared ray, massage, muscular movement exercise, the treatment phase is 20 days.
Efficacy determination:
Cure: facial symptom and sign disappears completely, and facial perception and muscular movement functional rehabilitation are normal.As volume stricture of vagina recovers, catacleisis, nasolabial fold is symmetrical, and bicker is without crooked; Effective: clinical symptoms sign disappears substantially, facial appearance is symmetrical, but slightly feels blunt or deviation while doing expression action.As volume stricture of vagina is most of, recover, eyelid firmly can be closed, and it is symmetrical that nasolabial fold is owed, and bicker is slightly crooked; Take a turn for the better: symptom and sign partly improves, while doing expression action, face has certain deviation. and volume stricture of vagina partly recovers, hypophasis, it is symmetrical that nasolabial fold is owed, and bicker is still crooked; Invalid: unchanged before and after diagnosis and treatment.
Result
After 2 courses for the treatment of or 20 days, each organizes curative effect in Table 1.
Table 1 clinical efficacy
| Group | n | Cure | Effective | Take a turn for the better | Cure rate (%) | Total effective rate (%) |
| Treatment group | 62 | 32 | 15 | 12 | 51.61 | 95.16 |
| Contrast 1 group | 50 | 13 | 13 | 15 | 26.00 | 82.00 |
| Contrast 2 groups | 50 | 9 | 11 | 13 | 18.00 | 66.00 |
As can be seen from Table 1, adopt Chinese medicine composition of the present invention aspect facial paralysis, to there is significant curative effect.
Case 1
Chen, female, 22 years old, in be admitted to hospital for 16th right side facial hemiparalysis 7 days of December in 2010.Right eyelid is sagging, catacleisis can not, right volume stricture of vagina disappears, frown, knit one's brows can not, Bell levies the positive, right side nasolabial fold shoals, bicker is askew to strong side, the gas leakage of the drum cheek, gargles and leaks, without amyotrophy, extremity muscular strength is normal, reflection normally.Previously body is strong, without genetic diseases.Head brain CT report is normal.Adopt TDP lamp to coordinate Chinese medicine composition composition powders 1 acupuncture points external application of the embodiment of the present invention 1 preparation to treat 10 times, every day 1 time, the using method of powder 1 is in powder, to add a small amount of water, with alcohol burner, heat and stir and become pasty state, treat that mass is slightly cool, get sterile gauze piece, mass is coated on gauze piece, at patient's yang white, the sun, dicang, cheek car with Quan Liao cave sticks 30min, volume stricture of vagina in right side recovers subsequently, nasolabial fold is symmetrical, it is normal to frown, knit one's brows, and in drum cheek people, ditch is without crooked, and facial expression is normal.After 3 months, follow up a case by regular visits to completely and recover.
Case 2
Wang, man, 37 years old.Being on home leave in December in 2012 strange land on the 29th, in way, is affected by the cold, and prominent sense in morning on next day mouthful eye is crooked to the right, invites remaining diagnosis and treatment.Crooked to the right depending on seeing bicker, left side disapperance of nasolabial sulcus, the subcutaneous pendant of left eye, praises unable.Stating right side cheek has numb pruritus burning sensation, and companion's xerostomia is irritated, the heating of the bilateral centre of the palm, and susceptible to lose temper due to restlessness, hectic fever night sweat during nighttime sleep, when rise morning, hair is as washed.It is pungent that thin inquiry have happiness food, the hobby of drinking.Existing 7 years of hypertension history, takes the depressor treatments such as nifedipine for a long time.Be measuring blood pressure 130/90mmHg.The few tongue of red tongue, wiry and frequent pulse is strong, adopts TDP lamp to coordinate Chinese medicine composition composition powders 1 acupuncture points external application of the embodiment of the present invention 1 preparation to treat 15 times, every day 1 time, the using method of powder 1 is in powder, to add a small amount of water, with alcohol burner, heating and stir becomes pasty state, treats that mass is slightly cool, gets sterile gauze piece, mass is coated on gauze piece, yang white, the sun, dicang, cheek car and cheekbone Liao cave patient stick 30minl, and after first quarter moon, distortion of commissure takes a turn for the better, strong before eyelid is praised.Patient side cheek numbness, pruritus, burning sensation lose.Yet after medicine, singultus is frequent recently, abdominal pain and distension, stool is black loose stool, day approximately 4～6 times, continual cure 10 times, distortion of commissure recovers as before.Nighttime sleep is micro-heating, the slightly sweating of awake occiput, and remaining disease is lost to the greatest extent.After 6 months, follow up a case by regular visits to completely and recover.
All above-mentioned these intellectual properties of primary enforcement, do not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only preferred embodiment of the present invention, is not the present invention to be done to the restriction of other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (6)
1. a Chinese medicine composition that is used for the treatment of facial paralysis, is characterized in that: the crude drug of described Chinese medicine composition comprises Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae, Herba Ecliptae, the Radix Astragali, Semen Cuscutae, Radix Bupleuri, Rhizoma Chuanxiong, Stigma Croci, Rhizoma Et Radix Notopterygii, Radix Gentianae Macrophyllae, Herba Hyperici Sampsonii, Herba Aristolochiae, Herba Fici Simplicissimae, Caulis et folium cryptotaeniae japonicae and Radix Glycyrrhizae.
2. Chinese medicine composition as claimed in claim 1, it is characterized in that: in described Chinese medicine composition, the weight of each crude drug is respectively Arisaema Cum Bile 50g～60g, Radix Isatidis 35g～45g, Ramulus Uncariae Cum Uncis 25g～35g, Radix Platycodonis 20g～30g, Fructus Liquidambaris 35g～45g, Herba Centipedae 25g～35g, Bombyx Batryticatus 15g～25g, Radix Gentianae 35g～45g, Herba Ecliptae 20g～30g, Radix Astragali 40g～50g, Semen Cuscutae 35g～45g, Radix Bupleuri 15g～25g, Rhizoma Chuanxiong 20g～30g, Stigma Croci 35g～45g, Rhizoma Et Radix Notopterygii 15g～25g, Radix Gentianae Macrophyllae 20g～30g, Herba Hyperici Sampsonii 30g～40g, Herba Aristolochiae 25g～35g, Herba Fici Simplicissimae 20g～30g, Caulis et folium cryptotaeniae japonicae 25g～35g and Radix Glycyrrhizae 35g～45g.
3. Chinese medicine composition as claimed in claim 1 or 2, is characterized in that: in described Chinese medicine composition, the weight of each crude drug is respectively Arisaema Cum Bile 55g, Radix Isatidis 40g, Ramulus Uncariae Cum Uncis 30g, Radix Platycodonis 25g, Fructus Liquidambaris 40g, Herba Centipedae 30g, Bombyx Batryticatus 20g, Radix Gentianae 40g, Herba Ecliptae 25g, Radix Astragali 45g, Semen Cuscutae 40g, Radix Bupleuri 20g, Rhizoma Chuanxiong 25g, Stigma Croci 40g, Rhizoma Et Radix Notopterygii 20g, Radix Gentianae Macrophyllae 25g, Herba Hyperici Sampsonii 35g, Herba Aristolochiae 30g, Herba Fici Simplicissimae 25g, Caulis et folium cryptotaeniae japonicae 30g and Radix Glycyrrhizae 40g.
4. the preparation method of Chinese medicine composition described in claims 1 to 3, is characterized in that, comprising:
The first step, Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae are ground into respectively to coarse powder, according to above-mentioned weight, mix, in mixture: the even moistening of ethanol mass ratio=1:1 ratio of determining alcohol 80%, airtight placement more than 10 hours, drops in percolate pot, floods 24 hours, percolation, percolate flow velocity 95～105L per hour; By this speed, constantly add determining alcohol is 80% ethanol simultaneously, in percolation process, keeps ethanol to be not less than powder, collect percolate and be medical material amount 8 times, merge percolate, and concentrating under reduced pressure is removed ethanol, obtains and gets dry extract, and is ground into the first powder;
Second step, is ground into respectively coarse powder by remaining component, according to above-mentioned weight, mixes, and decocts with water twice, adds for the first time 10 times of water gagings, decocts two hours, filters; Add for the second time 8 times of water gagings, decoct two hours, filter; Merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder;
The 3rd step, mixes the first powder and the second powder, forms described Chinese medicine composition.
5. a Chinese medicine composition composition powders that is used for the treatment of facial paralysis, is characterized in that: the crude drug of described Chinese medicine composition composition powders comprises Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae, Herba Ecliptae, the Radix Astragali, Semen Cuscutae, Radix Bupleuri, Rhizoma Chuanxiong, Stigma Croci, Rhizoma Et Radix Notopterygii, Radix Gentianae Macrophyllae, Herba Hyperici Sampsonii, Herba Aristolochiae, Herba Fici Simplicissimae, Caulis et folium cryptotaeniae japonicae and Radix Glycyrrhizae;
The preparation method of described Chinese medicine composition composition powders is specially,
The first step, Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae are ground into respectively to coarse powder, according to above-mentioned weight, mix, in mixture: the even moistening of ethanol mass ratio=1:1 ratio of determining alcohol 80%, airtight placement more than 10 hours, drops in percolate pot, floods 24 hours, percolation, percolate flow velocity 95～105L per hour; By this speed, constantly add determining alcohol is 80% ethanol simultaneously, in percolation process, keeps ethanol to be not less than powder, collect percolate and be medical material amount 8 times, merge percolate, and concentrating under reduced pressure is removed ethanol, obtains and gets dry extract, and is ground into the first powder;
Second step, is ground into respectively coarse powder by remaining component, according to above-mentioned weight, mixes, and decocts with water twice, adds for the first time 10 times of water gagings, decocts two hours, filters; Add for the second time 8 times of water gagings, decoct two hours, filter; Merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder;
The 3rd step, mixes the first powder and the second powder, forms described Chinese medicine composition composition powders.
6. the using method of Chinese medicine composition composition powders described in claim 5, it is characterized in that: in described Chinese medicine composition composition powders, add a small amount of water, with alcohol burner, heat and stir and become pasty state, treat that mass is slightly cool, get sterile gauze piece, mass is coated on gauze piece, at patient's yang white, the sun, dicang, cheek car with Quan Liao cave sticks 30min.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101062296A (en) * | 2007-06-01 | 2007-10-31 | 许丽辉 | Chinese-medicinal capsule for treating facial spasm and its preparing process |
| CN101773585A (en) * | 2010-02-21 | 2010-07-14 | 郑勇 | Chinese medicine for treating facial paralysis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101062296A (en) * | 2007-06-01 | 2007-10-31 | 许丽辉 | Chinese-medicinal capsule for treating facial spasm and its preparing process |
| CN101773585A (en) * | 2010-02-21 | 2010-07-14 | 郑勇 | Chinese medicine for treating facial paralysis |
Non-Patent Citations (1)
| Title |
|---|
| 王平: "面瘫的正治失治救治", 《光明中医》, vol. 12, no. 73, 31 December 1997 (1997-12-31), pages 22 - 24 * |
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