CN103690760B - A kind of Chinese medicine composition being used for the treatment of facial paralysis and preparation method thereof - Google Patents

A kind of Chinese medicine composition being used for the treatment of facial paralysis and preparation method thereof Download PDF

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CN103690760B
CN103690760B CN201310710889.8A CN201310710889A CN103690760B CN 103690760 B CN103690760 B CN 103690760B CN 201310710889 A CN201310710889 A CN 201310710889A CN 103690760 B CN103690760 B CN 103690760B
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radix
herba
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CN103690760A (en
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吕辉
许波
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Qingdao Central Hospital
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Abstract

The invention provides a kind of Chinese medicine composition being used for the treatment of facial paralysis and preparation method thereof, its crude drug comprises Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae, Herba Ecliptae, the Radix Astragali, Semen Cuscutae, Radix Bupleuri, Rhizoma Chuanxiong, Stigma Croci, Rhizoma Et Radix Notopterygii, Radix Gentianae Macrophyllae, Herba Hyperici Sampsonii, Herba Aristolochiae, Herba Fici Simplicissimae, Caulis et folium cryptotaeniae japonicae, Bulbus Fritillariae Cirrhosae, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygoni Multiflori and Radix Glycyrrhizae.Chinese medicine composition provided by the invention coordinates specific electromagnetic wave treatment, can significantly improve the therapeutic effect of facial paralysis, good effect, instant effect.

Description

A kind of Chinese medicine composition being used for the treatment of facial paralysis and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicine, particularly relate to a kind of Chinese powder medicine being used for the treatment of facial paralysis.
Background technology
Facial paralysis is one of common clinical.Modern medicine thinks many by virus or cold invasion and attack face nerve motor fiber, make it that pathological changes occur and cause the patient side portion mimetic musculature dyskinesia and occur that facial hemiparalysis is a kind of commonly encountered diseases of feature, also claiming facial paralysis, facial neuritis, bell's palsy.
This disease is common with adolescence.Can betide any age, without significantly seasonal, the child of person between twenty and fifty, postpartum women, weak old man, the young and the middle aged of suffering from cold after drinking, resistance difference is the primary attack object of facial paralysis.Be common clinical, easily leave over sequela if treated not in time.Facial paralysis onset is hurried, take facial hemiparalysis as main clinical manifestation.Due to the particularity of lesion, the ill rear outward appearance directly affecting patient facial region, brings larger inconvenience to patient's daily life.
Modern medicine is thought, passes through because bone facial canal only can hold nervus facialis, and nervus facialis, once there is inflammatory edema, must cause nervus facialis pressurized.Wind and cold, viral infection and autonomic nervous function instability etc. all can cause local nerve malnutrition, vasospasm, causes neural ischemia edema.Modern medical therapy method is more, and the main Western medicine that adopts alleviates nervus facialis edema, alleviates nerve compression and promotes neurological functional recovery, but unsatisfactory curative effect.
Motherland's medical science is thought, primary disease pathogenesis be battalion defend become estranged, that Wei Yang is solid, venation is hollow, heresy of wind and cold or wind heat invades sun is bright with shaoyang channel arteries and veins, and cause, blockage of main and collateral channels, muscles along the regular meridians stagnant through vapour lock lose support, vertical slow receipts of muscle fall ill, and controls suitable harmonizing yingfen and weifen, expelling wind and clearing away heat, promoting blood circulation to remove obstruction in the collateral.
The present invention is the further research made on the basis of patent 2013104714932 before, coordinates specific electromagnetic wave treatment, can significantly improve the therapeutic effect of facial paralysis, good effect, instant effect.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine being used for the treatment of facial paralysis, and it coordinates specific electromagnetic wave treatment, can significantly improve the therapeutic effect of facial paralysis, good effect, instant effect.
For solving the problems of the technologies described above, the invention provides and the invention provides a kind of Chinese medicine composition being used for the treatment of facial paralysis, its crude drug comprises Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae, Herba Ecliptae, the Radix Astragali, Semen Cuscutae, Radix Bupleuri, Rhizoma Chuanxiong, Stigma Croci, Rhizoma Et Radix Notopterygii, Radix Gentianae Macrophyllae, Herba Hyperici Sampsonii, Herba Aristolochiae, Herba Fici Simplicissimae, Caulis et folium cryptotaeniae japonicae, Bulbus Fritillariae Cirrhosae, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygoni Multiflori and Radix Glycyrrhizae.
Wherein, in described Chinese medicine composition, the weight of each crude drug is respectively:
Arisaema Cum Bile 50g ~ 60g, Radix Isatidis 35g ~ 45g, Ramulus Uncariae Cum Uncis 25g ~ 35g, Radix Platycodonis 20g ~ 30g, Fructus Liquidambaris 35g ~ 45g, Herba Centipedae 25g ~ 35g, Bombyx Batryticatus 15g ~ 25g, Radix Gentianae 35g ~ 45g, Herba Ecliptae 20g ~ 30g, Radix Astragali 40g ~ 50g, Semen Cuscutae 35g ~ 45g, Radix Bupleuri 15g ~ 25g, Rhizoma Chuanxiong 20g ~ 30g, Stigma Croci 35g ~ 45g, Rhizoma Et Radix Notopterygii 15g ~ 25g, Radix Gentianae Macrophyllae 20g ~ 30g, Herba Hyperici Sampsonii 30g ~ 40g, Herba Aristolochiae 25g ~ 35g, Herba Fici Simplicissimae 20g ~ 30g, Caulis et folium cryptotaeniae japonicae 25g ~ 35g, Bulbus Fritillariae Cirrhosae 10g ~ 20g, Radix Et Caulis Acanthopanacis Senticosi 10g ~ 20g, Radix Polygoni Multiflori 15g ~ 25g and Radix Glycyrrhizae 35g ~ 45g.
Wherein, in described Chinese medicine composition, the weight of each crude drug is respectively:
Arisaema Cum Bile 55g, Radix Isatidis 40g, Ramulus Uncariae Cum Uncis 30g, Radix Platycodonis 25g, Fructus Liquidambaris 40g, Herba Centipedae 30g, Bombyx Batryticatus 20g, Radix Gentianae 40g, Herba Ecliptae 25g, Radix Astragali 45g, Semen Cuscutae 40g, Radix Bupleuri 20g, Rhizoma Chuanxiong 25g, Stigma Croci 40g, Rhizoma Et Radix Notopterygii 20g, Radix Gentianae Macrophyllae 25g, Herba Hyperici Sampsonii 35g, Herba Aristolochiae 30g, Herba Fici Simplicissimae 25g, Caulis et folium cryptotaeniae japonicae 30g, Bulbus Fritillariae Cirrhosae 15g, Radix Et Caulis Acanthopanacis Senticosi 15g, Radix Polygoni Multiflori 20g and Radix Glycyrrhizae 40g.
Present invention also offers the preparation method of above-mentioned Chinese medicine composition, it is specially:
The first step, Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae are ground into coarse powder respectively, mix according to above-mentioned weight, by mixture: ethanol mass ratio=1 of determining alcohol 80%: 1 ratio uniform moistening, airtight placement more than 10 hours, drops in percolate pot, floods 24 hours, percolation, percolate flow velocity 95 ~ 105L per hour; Constantly add by this speed the ethanol that determining alcohol is 80% simultaneously, keep ethanol to be not less than powder in percolation process, collect 8 times that percolate is medical material amount, merge percolate, concentrating under reduced pressure removing ethanol, obtains and gets dry extract, be ground into the first powder;
Second step, is ground into coarse powder respectively by remaining components, mixes, decoct with water twice according to above-mentioned weight, and first time adds 10 times of water gagings, decocts two hours, filters; Second time adds 8 times of water gagings, decocts two hours, filters; Merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder;
3rd step, mixes the first powder and the second powder, forms described Chinese medicine composition.
Present invention also offers a kind of Chinese medicine composition composition powders being used for the treatment of facial paralysis, its crude drug comprises Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae, Herba Ecliptae, the Radix Astragali, Semen Cuscutae, Radix Bupleuri, Rhizoma Chuanxiong, Stigma Croci, Rhizoma Et Radix Notopterygii, Radix Gentianae Macrophyllae, Herba Hyperici Sampsonii, Herba Aristolochiae, Herba Fici Simplicissimae, Caulis et folium cryptotaeniae japonicae, Bulbus Fritillariae Cirrhosae, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygoni Multiflori and Radix Glycyrrhizae;
The preparation method of described Chinese medicine composition composition powders is specially,
The first step, Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae are ground into coarse powder respectively, mix according to above-mentioned weight, by mixture: ethanol mass ratio=1 of determining alcohol 80%: 1 ratio uniform moistening, airtight placement more than 10 hours, drops in percolate pot, floods 24 hours, percolation, percolate flow velocity 95 ~ 105L per hour; Constantly add by this speed the ethanol that determining alcohol is 80% simultaneously, keep ethanol to be not less than powder in percolation process, collect 8 times that percolate is medical material amount, merge percolate, concentrating under reduced pressure removing ethanol, obtains and gets dry extract, be ground into the first powder;
Second step, is ground into coarse powder respectively by remaining components, mixes, decoct with water twice according to above-mentioned weight, and first time adds 10 times of water gagings, decocts two hours, filters; Second time adds 8 times of water gagings, decocts two hours, filters; Merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder;
3rd step, mixes the first powder and the second powder, forms described Chinese medicine composition composition powders.
Present invention also offers the using method of above-mentioned Chinese medicine composition, a small amount of water is added in described Chinese medicine composition composition powders, heat with alcohol burner and stir and become pasty state, treat that mass is slightly cool, get sterile gauze block, mass is coated on gauze piece, at the yang white of patient, the sun, dicang, cheek car with Quan Liao cave sticks 30min.
Beneficial effect of the present invention:
The Chinese medicine being used for the treatment of facial paralysis provided by the invention, it coordinates specific electromagnetic wave treatment, can significantly improve the therapeutic effect of facial paralysis, good effect, instant effect.
Detailed description of the invention
Facial paralysis belongs to the traditional Chinese medical science " apoplexy " category, and its pathogenesis is the positive QI-insufficiency of body, and ailment said due to cold or exposure is taken advantage of a weak point in opponent's defence into apoplex involving the channels and collaterals, and priming expectorant is turbid, and wind-phlegm hinders bright in sun, few sun, sun meridians, therefore sees that facial hemiparalysis, dysphonia, eyelid can not close.Motherland's medical science is thought, facial paralysis is due to the positive QI-insufficiency of body, and face venation is hollow, and pathogen attacks facial venation in an opponent's defence, numbness air resister, muscle arteries and veins lose and support, and facial muscle is vertical slowly not to be received and causes.
The pathogeny of primary disease is weak mainly due to healthy energy element, and QI and blood is popular not smooth, causes facial side venation hollow, and Wei Yang is not solid, protect table function low, and wind-engaging causes.Wind has exogenous wind endogenous wind not.And wind being the primary exopathogen, how doublely hold that its is evil under the arm, as wind and cold, wind heat, rheumatism, wind-phlegm blood stasis etc., attack bright, sun, the sun less the muscles along the regular meridians venation of sun and a side surface part disharmony between QI and blood occur, channels loses supports, cause and of flaccid musclesly not receive, facial both sides channels disequilibrium, cause that disease side face muscle is askew forms facial hemiparalysis to strong side.
TDP is specific electromagnetic wave, can match with human biological electricity wavelength and produce resonance, and immunity moderation function and enhanced biological interior " self-regulation system ", play the effect of inflammation-inhibiting, analgesia, raising immunity of organisms.The infrared-ray that TDP lamp sends can improve local blood circulation, promotes that inflammation and local edema disappear, accelerates repair of damaged tissues.And nebula wind scoop place is equivalent to the body surface inner projection point of stylomastoid foramen, there is nervus facialis outlet etc. under cave, local blood circulation and lymph circulation can be improved with this region of TDP light irradiation, facial paralysis is alleviated.
The present invention adopts Chinese powder medicine to coordinate TDP facial paralysis, is the combined effect by heating power and medicine, accelerates blood circulation by skin expansion tiny blood vessels, from outward appearance to inner essence, in warm middle enforcement treatment.So directly dredge facial meridians by Chinese medicine and Re Ke, promote regional flow, improve blood and supply and nutrition, make to ooze out minimizing, absorption of edema, thus reach therapeutic purposes.
Based on this, the invention provides a kind of Chinese medicine composition being used for the treatment of facial paralysis, its crude drug comprises Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae, Herba Ecliptae, the Radix Astragali, Semen Cuscutae, Radix Bupleuri, Rhizoma Chuanxiong, Stigma Croci, Rhizoma Et Radix Notopterygii, Radix Gentianae Macrophyllae, Herba Hyperici Sampsonii, Herba Aristolochiae, Herba Fici Simplicissimae, Caulis et folium cryptotaeniae japonicae, Bulbus Fritillariae Cirrhosae, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygoni Multiflori and Radix Glycyrrhizae.
Further, described Chinese medicine composition is only made up of above-mentioned raw materials medicine.
In described Chinese medicine composition, the weight of each crude drug is respectively:
Arisaema Cum Bile 50g ~ 60g, Radix Isatidis 35g ~ 45g, Ramulus Uncariae Cum Uncis 25g ~ 35g, Radix Platycodonis 20g ~ 30g, Fructus Liquidambaris 35g ~ 45g, Herba Centipedae 25g ~ 35g, Bombyx Batryticatus 15g ~ 25g, Radix Gentianae 35g ~ 45g, Herba Ecliptae 20g ~ 30g, Radix Astragali 40g ~ 50g, Semen Cuscutae 35g ~ 45g, Radix Bupleuri 15g ~ 25g, Rhizoma Chuanxiong 20g ~ 30g, Stigma Croci 35g ~ 45g, Rhizoma Et Radix Notopterygii 15g ~ 25g, Radix Gentianae Macrophyllae 20g ~ 30g, Herba Hyperici Sampsonii 30g ~ 40g, Herba Aristolochiae 25g ~ 35g, Herba Fici Simplicissimae 20g ~ 30g, Caulis et folium cryptotaeniae japonicae 25g ~ 35g, Bulbus Fritillariae Cirrhosae 10g ~ 20g, Radix Et Caulis Acanthopanacis Senticosi 10g ~ 20g, Radix Polygoni Multiflori 15g ~ 25g and Radix Glycyrrhizae 35g ~ 45g.
In described Chinese medicine composition, the weight of each crude drug is respectively:
Arisaema Cum Bile 55g, Radix Isatidis 40g, Ramulus Uncariae Cum Uncis 30g, Radix Platycodonis 25g, Fructus Liquidambaris 40g, Herba Centipedae 30g, Bombyx Batryticatus 20g, Radix Gentianae 40g, Herba Ecliptae 25g, Radix Astragali 45g, Semen Cuscutae 40g, Radix Bupleuri 20g, Rhizoma Chuanxiong 25g, Stigma Croci 40g, Rhizoma Et Radix Notopterygii 20g, Radix Gentianae Macrophyllae 25g, Herba Hyperici Sampsonii 35g, Herba Aristolochiae 30g, Herba Fici Simplicissimae 25g, Caulis et folium cryptotaeniae japonicae 30g, Bulbus Fritillariae Cirrhosae 15g, Radix Et Caulis Acanthopanacis Senticosi 15g, Radix Polygoni Multiflori 20g and Radix Glycyrrhizae 40g.
Each crude drug pharmacology is as follows:
Arisaema Cum Bile: bitter in the mouth, micro-pungent, cool in nature, returns lung, liver, spleen channel, has removing heat-phlegm, effect of dispelling wind and relieving convulsion, for phlegm-heat cough, coughs up phlegm yellow thick, middle wind-phlegm fan, the diseases such as demented infantile convulsion.
Radix Isatidis: bitter in the mouth, cold in nature, enters the heart, liver, gallbladder, stomach warp, has the effect of heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving, be used for the treatment of maculae caused by violent heat pathogen; High heat headache; Major part pestilence; Crimson tongue is purple dark, scarlet fever; Erysipelas; Mumps; Sore throat; Skin ulcer is swollen, carbuncle; Chickenpox; Measles; Hepatitis; Influenza, epidemic encephalitis, encephalitis b, pneumonia, the diseases such as coma tells nosebleed, pharyngeal swelling, acute catarrhal conjunctivitis, skin ulcer rash.
Ramulus Uncariae Cum Uncis: sweet in the mouth, slightly warm in nature, enters Liver Channel, has the effect of heat clearing away, suppressing the hyperactive liver and subsiding YANG, relieving spasm by subduing liver-wind, and be mainly used in the anxious raw wind of heat or the caused spasm of liver-wind stirring up internally, twitch, restlessness, excessive rising of liver-YANG or Liver Channel have the headache of heat dizzy, the symptoms such as conjunctival congestion and swelling pain.
Radix Platycodonis: bitter in the mouth, pungent, property is put down, and returns lung meridian, has lung qi dispersing, sore-throat relieving, eliminates the phlegm, effect of evacuation of pus, cures mainly cough with copious phlegm, uncomfortable in chest smooth, pharyngalgia hoarseness, the diseases such as lung abscess vomiting pus.
Fructus Liquidambaris: bitter in the mouth, property is put down, and returns liver, kidney channel, has dispelling, collateral-activating, effect that diuretic stimulates the menstrual flow, for arthralgia, numbness contracture, edema distension, the diseases such as the few amenorrhea of breast.
Herba Centipedae: latin name CentipedaeHebra, acrid in the mouth, warm in nature, enter lung, Liver Channel, there is cold-dispelling, clearing the nasal passage, eliminating phlegm and stopping cough, the effect of dissipating blood stasis for subsidence of swelling, for wind and cold table disease, nasal obstruction watery nasal discharge and nasal sinusitis, cough with copious phlegm, pertussis, the diseases such as sore, carbuncle and painful swelling.
Bombyx Batryticatus: acrid in the mouth, salty, property is put down, and return liver, lung, stomach warp, have expelling wind to relieve convulsion, dissipating phlegm and resolving masses, effect of heat-clearing and toxic substances removing dampness, cures mainly convulsion with spasms, laryngopharynx swelling and pain, and submandibular lymph nodes is scorching, facial paralysis, the diseases such as skin pruritus.
Radix Gentianae: bitter in the mouth, cold in nature, enters liver, gallbladder meridian, has heat clearing and damp drying, falls the effect of letting out liver-fire and function of gallbladder promoting, and the breast side of body being mainly used in dampness-heat of the liver caused is had a pain, and bitter taste is deaf, conjunctival congestion and swelling pain; Jaundice due to damp-heat; The dizzy order of flaming up of liver-fire swells; The high heat of liver-fire wind-transformation is through taking out; The disease such as leucorrhea, dysuria of damp invasion of lower energizer.
Herba Ecliptae: sweet in the mouth, acid, cold in nature, return liver, kidney channel, play liver and kidney tonifying, the effect of cooling blood for hemostasis, for having a dizzy spell caused by the hepatic and renal YIN deficiency, blurring of vision, soreness of the waist and knees; Be suitable for the deficiency of YIN and have hot person, be used for the treatment of the haematemesis of accumulated heat in stomach, the symptoms such as the hemoptysis of injury of blood vessel of the lung by heat, Herba Ecliptae has inhibitory action to staphylococcus aureus, Bacillus typhi, S. sonnei, bacillus pyocyaneus, can obvious enhancing non-specific immunity and cellular immune function.
The Radix Astragali: sweet in the mouth, warm in nature, enter spleen, lung meridian, have tonification spleen soil, elevate a turnable ladder yang-energy, strengthening superficial resistance to stop perspiration, the effects such as holder skin ulcer granulation promoting, are mainly used in the weak anorexia and loose stool that deficiency of both the splenic and pulmonary QI is caused, shortness of breath and palpitation, the visceroptosis of sinking of QI of middle-JIAO, the metrorrhagia of QI failing to control blood is had blood in stool, chronic diarrhea proctoptosis; The spontaneous sweating of exterior deficiency, the diseases such as insufficiency of vital energy and blood, the Radix Astragali makes contractile ability strengthen, and can improve the blood circulation of whole body, can coronary artery dilator, Renal vascular and Rhizoma Bistortae peripheral vessel, make cutaneous circulation vigorous; The nonspecific immunity power of body can be improved, protect the liver and fall hypoglycemic effect, have inhibitory action to staphylococcus, blood dissolubility streptococcus, Diplococcus pneumoniae, dysentery bacterium etc.
Semen Cuscutae: sweet in the mouth, pungent, property is put down, and enters liver,kidney,spleen warp, there is the kidney invigorating and essence nourishing, effect of nourishing the liver to improve visual acuity, cure mainly the sexual impotence of insufficiency of kidney-YANG, seminal emission premature ejaculation, frequent micturition, dizziness and tinnitus, to suffer from a deficiency of the kidney pain in the lumbar region, married woman's leukorrhagia, nausea is not solid, and the binocular of both liver and kidney deficiency, deficiency of liver-blood is dim-sighted, blurring of vision, the loose stool stomachache of asthenia of both the spleen and kidney, the diseases such as aqueous-grainy diarrhea.
Radix Bupleuri: bitter in the mouth, cold nature, returns Liver Channel, gallbladder meridian, have evacuate bring down a fever, effect of yang invigorating soothing liver-QI, for cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, the diseases such as uterus comes off, menoxenia.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature, return liver, gallbladder, pericardium channel, have blood-activating and qi-promoting, effect of wind-expelling pain-stopping, cures mainly menoxenia; Amenorrhea dysmenorrhea; The stagnant raw meat pain of the stasis of blood in puerperal; Lump in the abdomen lump; Pain in chest and hypochondrium; Have a headache dizzy; Anemofrigid-damp arthralgia; Traumatic injury; The diseases such as ulcer sores.
Stigma Croci: sweet in the mouth, property is put down, energy blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens, pain relieving.Be used for the treatment of troubled thoughts pent-up, chest and diaphragm painful abdominal mass is vexed, and spit blood, typhoid fever is gone mad, and frightened fear in a trance, women's amenorrhea, stasis menoxenia, prolonged lochia, blood stasis is had a pain, measles, the diseases such as traumatic injury.
Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature, enter kidney, urinary bladder channel, have effect of the cold expelling that induces sweat, expelling wind and dampness, pain relieving, have wind and cold folder wet table disease, disease sees that fever with aversion to cold, headache are as wrapped up in, neck rigid back pain, the diseases such as limbs are heavy, and joint is ached, anemofrigid-damp arthralgia.
Radix Gentianae Macrophyllae: latin name GentianaeMacrophyllaeRadix, acrid in the mouth, hardship, cold nature, returns stomach warp, Liver Channel, gallbladder meridian, have wind-damp dispelling, relaxing muscles and tendons network, effect of clearind deficient heat, cures mainly rheumatic arthralgia, the contracture of muscle arteries and veins, the diseases such as joint is ached, afternoon fever, infantile malnutrition heating.
Herba Hyperici Sampsonii: bitter in the mouth, pungent, cold in nature, return liver, spleen channel, there is removing pathogenic heat from blood and toxic substance from the body, promoting blood flow to regulate menstruation, effect of dispelling wind and removing obstruction in the collateral, cure mainly various hemorrhage, enteritis and dysentery, acute mastitis, carbuncle furunculosis, scald, venom, menoxenia, dysmenorrhea, leucorrhea, traumatic injury, rheumatic arthralgia, the diseases such as aphtha.
Herba Aristolochiae: latin name HerbaAristolochiae, bitter in the mouth; Warm in nature, return liver, spleen, kidney channel, have circulation of qi promoting removing dampness, effect of promoting blood circulation and stopping pain, cures mainly stomachache, colicky, edema during pregnancy, and puerperal, vim and vigour were suffered from abdominal pain, rheumatalgia.Promoting flow of QI and blood, pain relieving, diuresis.Edema during pregnancy, breast is suffered from abdominal pain, colic, the diseases such as rheumatalgia.
Herba Fici Simplicissimae: sweet, tepor, has invigorating the spleen for eliminating dampness, promoting the circulation of QI and reducing phlegm, effect of relaxing muscles and tendons and activating QI and blood in the collateral, cures mainly pulmonary tuberculosis cough, chronic bronchitis, rheumatic arthritis, lumbago and skelalgia, insufficiency of the spleen edema, after being ill the disease such as night sweat.
Bulbus Fritillariae Cirrhosae: bitter in the mouth, sweet, cold nature, enters lung, heart channel, has clearing heat and moistening lung, the effect of preventing phlegm from forming and stopping coughing, for lung-heat type cough, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood, the card such as cough due to consumptive disease, spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, sore throat, acute mastitis.
Radix Et Caulis Acanthopanacis Senticosi: acrid in the mouth, hardship, micro-sweet, warm in nature, enters spleen, kidney, heart channel, there is replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization, effect of expelling wind and removing dampness, soft for anemofrigid-damp arthralgia, lumbocrural pain, muscles and bones flaccidity, be slow in action, the card such as body weakness with emaciation is weak, traumatic injury, fracture, edema, beriberi, uncontrolled urination are itched.
Radix Polygoni Multiflori: bitter in the mouth, sweet, puckery, slightly warm in nature, returns liver, kidney channel, has effect of nourishing the blood and yin, loosening bowel to relieve constipation, cures mainly blood deficiency Light-headedness; Cardiopalmus; Insomnia; The soreness of the waist and knees of the hepatic and renal YIN deficiency; Early whitening of beard and hair; Tinnitus; Seminal emission; Dryness of the intestine constipation; Chronic malaria body is empty; Rubella pruritus; Carbuncle sore; Scrofula; The cards such as hemorrhoid, Radix Polygoni Multiflori can make telangiectasis.
Caulis et folium cryptotaeniae japonicae: acrid in the mouth is bitter; Property is put down, and has dispelling wind stopping cough; Eliminating damp, detoxifying; Effect of blood-activating analgetic, cures mainly pneumonia, pulmonary abscess, gonorrhea, hernia, acute toothache, and carbuncle furuncle swells, herpes zoster, the diseases such as skin pruritus.
Present invention also offers the preparation method of above-mentioned Chinese medicine composition composition powders, it is specially:
The first step, Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae are ground into coarse powder respectively, mix according to above-mentioned weight, by mixture: ethanol mass ratio=1 of determining alcohol 80%: 1 ratio uniform moistening, airtight placement more than 10 hours, drops in percolate pot, floods 24 hours, percolation, percolate flow velocity 95 ~ 105L per hour; Constantly add by this speed the ethanol that determining alcohol is 80% simultaneously, keep ethanol to be not less than powder in percolation process, collect 8 times that percolate is medical material amount, merge percolate, concentrating under reduced pressure removing ethanol, obtains and gets dry extract, be ground into the first powder;
Second step, is ground into coarse powder respectively by remaining components, mixes, decoct with water twice according to above-mentioned weight, and first time adds 10 times of water gagings, decocts two hours, filters; Second time adds 8 times of water gagings, decocts two hours, filters; Merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder;
3rd step, mixes the first powder and the second powder, forms described Chinese medicine composition composition powders.
Present invention also offers the using method of above-mentioned Chinese medicine composition, a small amount of water is added in described Chinese medicine composition composition powders, heat with alcohol burner and stir and become pasty state, treat that mass is slightly cool, get sterile gauze block, mass is coated on gauze piece, at the yang white of patient, the sun, dicang, cheek car with Quan Liao cave sticks 30min.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese medicine composition composition powders 1
Arisaema Cum Bile 55g, Radix Isatidis 40g, Ramulus Uncariae Cum Uncis 30g, Radix Platycodonis 25g, Fructus Liquidambaris 40g, Herba Centipedae 30g, Bombyx Batryticatus 20g, Radix Gentianae 40g are ground into coarse powder respectively, mixing, by mixture: ethanol mass ratio=1 of determining alcohol 80%: 1 ratio uniform moistening, airtight placement more than 10 hours, drop in percolate pot, flood 24 hours, percolation, percolate flow velocity 95L per hour, constantly add by this speed the ethanol that determining alcohol is 80% simultaneously, ethanol is kept to be not less than powder in percolation process, collect 8 times that percolate is medical material amount, merge percolate, concentrating under reduced pressure removing ethanol, obtain and get dry extract, be ground into the first powder, by Herba Ecliptae 25g, Radix Astragali 45g, Semen Cuscutae 40g, Radix Bupleuri 20g, Rhizoma Chuanxiong 25g, Stigma Croci 40g, Rhizoma Et Radix Notopterygii 20g, Radix Gentianae Macrophyllae 25g, Herba Hyperici Sampsonii 35g, Herba Aristolochiae 30g, Herba Fici Simplicissimae 25g, Caulis et folium cryptotaeniae japonicae 30g, Bulbus Fritillariae Cirrhosae 15g, Radix Et Caulis Acanthopanacis Senticosi 15g, Radix Polygoni Multiflori 20g and Radix Glycyrrhizae 40g is ground into coarse powder respectively, mixing, decoct with water twice, first time adds 10 times of water gagings, decoct two hours, filter, second time adds 8 times of water gagings, decocts two hours, filters, merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder, the first powder and the second powder is mixed, and forms described Chinese medicine composition composition powders 1.
Embodiment 2 Chinese medicine composition composition powders 2
Arisaema Cum Bile 50g, Radix Isatidis 35g, Ramulus Uncariae Cum Uncis 25g, Radix Platycodonis 20g, Fructus Liquidambaris 35g, Herba Centipedae 25g, Bombyx Batryticatus 15g, Radix Gentianae 35g are ground into coarse powder respectively, mixing, by mixture: ethanol mass ratio=1 of determining alcohol 80%: 1 ratio uniform moistening, airtight placement more than 10 hours, drop in percolate pot, flood 24 hours, percolation, percolate flow velocity 95L per hour, constantly add by this speed the ethanol that determining alcohol is 80% simultaneously, ethanol is kept to be not less than powder in percolation process, collect 8 times that percolate is medical material amount, merge percolate, concentrating under reduced pressure removing ethanol, obtain and get dry extract, be ground into the first powder, by Herba Ecliptae 20g, Radix Astragali 40g, Semen Cuscutae 35g, Radix Bupleuri 15g, Rhizoma Chuanxiong 20g, Stigma Croci 35g, Rhizoma Et Radix Notopterygii 15g, Radix Gentianae Macrophyllae 20g, Herba Hyperici Sampsonii 30g, Herba Aristolochiae 25g, Herba Fici Simplicissimae 20g, Caulis et folium cryptotaeniae japonicae 25g, Bulbus Fritillariae Cirrhosae 10g, Radix Et Caulis Acanthopanacis Senticosi 10g, Radix Polygoni Multiflori 15g and Radix Glycyrrhizae 35g is ground into coarse powder respectively, mixing, decoct with water twice, first time adds 10 times of water gagings, decoct two hours, filter, second time adds 8 times of water gagings, decocts two hours, filters, merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder, the first powder and the second powder is mixed, and forms described Chinese medicine composition composition powders 2.
Embodiment 3
Arisaema Cum Bile 60g, Radix Isatidis 45g, Ramulus Uncariae Cum Uncis 35g, Radix Platycodonis 30g, Fructus Liquidambaris 45g, Herba Centipedae 35g, Bombyx Batryticatus 25g, Radix Gentianae 45g are ground into coarse powder respectively, mixing, by mixture: ethanol mass ratio=1 of determining alcohol 80%: 1 ratio uniform moistening, airtight placement more than 10 hours, drop in percolate pot, flood 24 hours, percolation, percolate flow velocity 95L per hour, constantly add by this speed the ethanol that determining alcohol is 80% simultaneously, ethanol is kept to be not less than powder in percolation process, collect 8 times that percolate is medical material amount, merge percolate, concentrating under reduced pressure removing ethanol, obtain and get dry extract, be ground into the first powder, by Herba Ecliptae 30g, Radix Astragali 50g, Semen Cuscutae 45g, Radix Bupleuri 25g, Rhizoma Chuanxiong 30g, Stigma Croci 45g, Rhizoma Et Radix Notopterygii 25g, Radix Gentianae Macrophyllae 30g, Herba Hyperici Sampsonii 40g, Herba Aristolochiae 35g, Herba Fici Simplicissimae 30g, Caulis et folium cryptotaeniae japonicae 35g, Bulbus Fritillariae Cirrhosae 15g, Radix Et Caulis Acanthopanacis Senticosi 15g, Radix Polygoni Multiflori 20g and Radix Glycyrrhizae 45g is ground into coarse powder respectively, mixing, decoct with water twice, first time adds 10 times of water gagings, decoct two hours, filter, second time adds 8 times of water gagings, decocts two hours, filters, merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder, the first powder and the second powder is mixed, and forms described Chinese medicine composition composition powders 3.
Clinical data
Patient comes from December, 2007 to 2013 year March, totally 130 examples, wherein, man 70 example, female 60 example, 16 ~ 73 years old age, the course of disease 7 days ~ 6 months 72 examples, 6 months ~ 1 year 58 examples, left side facial paralysis 69 example, right side facial paralysis 61 example, be divided into 3 groups, be respectively treatment group 50 example, contrast 1 group of 40 example and contrast 2 group of 40 example.
Diagnostic criteria is with reference to national higher medical institution teaching material " neural medicine ", " subject of acupuncture and moxibustion theraphy ".Get rid of the facial paralysis that parotitis, otitis media, tumor, wound, cerebral hemorrhage, cerebral infarction, oncothlipsis etc. are caused.Clinical manifestation is sudden onset, and a side surface part is stiff, numb, lax, can not make wrinkle volume, close order, rouse the actions such as cheek, bicker slants tiltedly to strong, and the sleeping with eyes half-closed of sick side is shed tears, and volume stricture of vagina disappears or shoals, during feed, food debris is often stranded in the tooth buccal space of disease side, and often has saliva to flow out.Or from the beginning of after having ear or under ear or under ear and face ache, or 2/3 hypogeusia or disappearance, even hyperacusis etc. before Ipsilateral tongue.
Therapeutic Method
Treatment group: add a small amount of water in the powder 1 embodiment 1 prepared, heat with alcohol burner and stir and become pasty state, treat that mass is slightly cool, get sterile gauze block, mass is coated on gauze piece, at the yang white of patient, the sun, dicang, cheek car with Quan Liao cave sticks 30min, adopt TDP light irradiation simultaneously: with TDP irradiate Ipsilateral Wangue, nebula wind to just leading, cheek car region, continue 30min every day 1 time, be for 10 times a course for the treatment of at every turn, have a rest and carry out next course for the treatment of after 1 day, totally 2 courses for the treatment of.
Contrast 1 group: adopt BT-701-1B electrical stunning device, dilatational wave, electro acupuncture yang white, the sun, dicang, cheek car He Quan Liao cave, simultaneously with TDP irradiate Ipsilateral Wangue, nebula wind to just leading, cheek car region, each continue 30min every day 1 time, be for 10 times a course for the treatment of, have a rest and carry out next course for the treatment of after 1 day, totally 2 courses for the treatment of.
Contrast 2 groups: western medicine routine treatment: 1. glucocorticoid application: prednisone (20 ~ 30mg) or dexamethasone (1.5 ~ 3.0mg) 1/d, oral, continuous 7 ~ 10d; 2. use vasodilation to improve microcirculation, alleviate edema, 706 plasma substitutes or low molecular dextran 250 ~ 500mL, quiet 1 time/d, continuous 7 ~ 10d; 3. the application of neurotrophy metabolic drug: vitamin B 150 ~ 100mg, vitamin B 12100 μ g, citicoline 250mg, ubiquinone 105 ~ 10mg etc., intramuscular injection 1d1 time; 4. coordinate the local physical therapys such as infrared ray, massage, muscular movement exercise, the treatment phase is 20 days.
Efficacy determination:
Cure: facial symptom and sign disappears completely, facial perception and muscular movement functional rehabilitation normal.As volume stricture of vagina recovers, catacleisis, nasolabial fold is symmetrical, and bicker is without crooked; Effective: Clinical symptom and sign disappears substantially, facial appearance is symmetrical, but slightly feels blunt or deviation when doing expression action.As volume stricture of vagina major part is recovered, eyelid firmly can close, and nasolabial fold owes symmetrical, and bicker is slightly crooked; Take a turn for the better: symptom and sign part is improved, when doing expression action, face has certain deviation. and volume stricture of vagina part is recovered, hypophasis, and nasolabial fold owes symmetrical, and bicker is still crooked; Invalid: unchanged before and after diagnosis and treatment.
Result
After 2 courses for the treatment of or 20 days, each group curative effect is in table 1.
Table 1 clinical efficacy
As can be seen from Table 1, adopt Chinese medicine composition of the present invention in facial paralysis, have significant curative effect.
All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (2)

1. be used for the treatment of a preparation method for the Chinese medicine composition of facial paralysis, it is characterized in that:
In described Chinese medicine composition, the weight of each crude drug is respectively Arisaema Cum Bile 50g ~ 60g, Radix Isatidis 35g ~ 45g, Ramulus Uncariae Cum Uncis 25g ~ 35g, Radix Platycodonis 20g ~ 30g, Fructus Liquidambaris 35g ~ 45g, Herba Centipedae 25g ~ 35g, Bombyx Batryticatus 15g ~ 25g, Radix Gentianae 35g ~ 45g, Herba Ecliptae 20g ~ 30g, Radix Astragali 40g ~ 50g, Semen Cuscutae 35g ~ 45g, Radix Bupleuri 15g ~ 25g, Rhizoma Chuanxiong 20g ~ 30g, Stigma Croci 35g ~ 45g, Rhizoma Et Radix Notopterygii 15g ~ 25g, Radix Gentianae Macrophyllae 20g ~ 30g, Herba Hyperici Sampsonii 30g ~ 40g, Herba Aristolochiae 25g ~ 35g, Herba Fici Simplicissimae 20g ~ 30g, Caulis et folium cryptotaeniae japonicae 25g ~ 35g, Bulbus Fritillariae Cirrhosae 10g ~ 20g, Radix Et Caulis Acanthopanacis Senticosi 10g ~ 20g, Radix Polygoni Multiflori 15g ~ 25g and Radix Glycyrrhizae 35g ~ 45g,
The preparation method of described Chinese medicine composition comprises,
The first step, Arisaema Cum Bile, Radix Isatidis, Ramulus Uncariae Cum Uncis, Radix Platycodonis, Fructus Liquidambaris, Herba Centipedae, Bombyx Batryticatus, Radix Gentianae are ground into coarse powder respectively, mix according to above-mentioned weight, by mixture: ethanol mass ratio=1 of determining alcohol 80%: 1 ratio uniform moistening, airtight placement more than 10 hours, drops in percolate pot, floods 24 hours, percolation, percolate flow velocity 95 ~ 105L per hour; Constantly add by this speed the ethanol that determining alcohol is 80% simultaneously, keep ethanol to be not less than powder in percolation process, collect 8 times that percolate is medical material amount, merge percolate, concentrating under reduced pressure removing ethanol, obtains and gets dry extract, be ground into the first powder;
Second step, is ground into coarse powder respectively by remaining components, mixes, decoct with water twice according to above-mentioned weight, and first time adds 10 times of water gagings, decocts two hours, filters; Second time adds 8 times of water gagings, decocts two hours, filters; Merging filtrate, concentrating under reduced pressure, except anhydrating, obtains and gets dry extract, and is ground into the second powder;
3rd step, mixes the first powder and the second powder, forms described Chinese medicine composition composition powders.
2. preparation method as claimed in claim 1, is characterized in that: in described Chinese medicine composition, the weight of each crude drug is respectively Arisaema Cum Bile 55g, Radix Isatidis 40g, Ramulus Uncariae Cum Uncis 30g, Radix Platycodonis 25g, Fructus Liquidambaris 40g, Herba Centipedae 30g, Bombyx Batryticatus 20g, Radix Gentianae 40g, Herba Ecliptae 25g, Radix Astragali 45g, Semen Cuscutae 40g, Radix Bupleuri 20g, Rhizoma Chuanxiong 25g, Stigma Croci 40g, Rhizoma Et Radix Notopterygii 20g, Radix Gentianae Macrophyllae 25g, Herba Hyperici Sampsonii 35g, Herba Aristolochiae 30g, Herba Fici Simplicissimae 25g, Caulis et folium cryptotaeniae japonicae 30g, Bulbus Fritillariae Cirrhosae 15g, Radix Et Caulis Acanthopanacis Senticosi 15g, Radix Polygoni Multiflori 20g and Radix Glycyrrhizae 40g.
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CN101062296A (en) * 2007-06-01 2007-10-31 许丽辉 Chinese-medicinal capsule for treating facial spasm and its preparing process
CN101773585A (en) * 2010-02-21 2010-07-14 郑勇 Chinese medicine for treating facial paralysis

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CN101062296A (en) * 2007-06-01 2007-10-31 许丽辉 Chinese-medicinal capsule for treating facial spasm and its preparing process
CN101773585A (en) * 2010-02-21 2010-07-14 郑勇 Chinese medicine for treating facial paralysis

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