CN103503911A - Acaricidal combination containing acequinocyl - Google Patents
Acaricidal combination containing acequinocyl Download PDFInfo
- Publication number
- CN103503911A CN103503911A CN201210215651.3A CN201210215651A CN103503911A CN 103503911 A CN103503911 A CN 103503911A CN 201210215651 A CN201210215651 A CN 201210215651A CN 103503911 A CN103503911 A CN 103503911A
- Authority
- CN
- China
- Prior art keywords
- acequinocyl
- mite
- weight ratio
- active component
- kun
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses an acaricidal combination containing acequinocyl. The acaricidal combination contains an active ingredient A and an active ingredient B, wherein the active ingredient A is selected from the acequinocyl, the active ingredient B is selected from any one of the following compounds: clofentezine, azacyclotin, fenbutatin oxide, flutenzine and bromopropylate, and the weight ratio of the active ingredient A to the active ingredient B is 1:80-80:1. The combination has a synergistic effect on various pest mites damaging the agricultural production, the dosage of pesticides is reduced, the residual quantity of the pesticides on crops is reduced, and the environmental pollution is alleviated. The combination is safe for people and livestock and has good environmental compatibility, and the pest mites do not easily have drug resistance.
Description
Technical field
The invention belongs to technical field of pesticide, relate to the application of a kind of miticide composition containing acequinocyl on crops evil mite.
Background technology
Acequinocyl (acequinocyl) chemical name: 2-(acetoxyl group) 3-dodecyl-1,4-naphthoquinone, molecular formula: C
24h
32o
4.Acequinocyl is naphthoquinone derivatives, is mainly contact killing type miticide, has the toxicity of ingesting concurrently.In mite body, be hydrolyzed into 2-dodecyl-3-hydroxyl-1,4-naphthoquinone, and combine with the Qo site on electronics transfering channel in mitochondria, thereby suppress electronics transmission.
Two (the 2-chlorphenyls)-1,2,4 of clofentezine (Clofentezine) chemical name: 3,6-, 5-tetrazine, molecular formula: C
14h
8c
12n
4.Clofentezine is special efficacy miticide, lasting medicine.If effective to occurring in ovum and the mite of panonychus ulmi on fruit tree, cotton, ornamental plants, congo red spider, harmless to Predatory Mites, natural enemy.
Azacyclotin (Azocyclotin) chemical name: 1-(thricyclohexyl stannyl)-1-hydrogen-1,2,4-triazole, molecular formula: C20H35N3Sn.Azacyclotin is the stronger broad spectrum activity miticide of action of contace poison, if can kill mite, one-tenth mite and summer egg, invalid to winter egg.Light and rainwater are had to good stability, and the longevity of residure is longer.Under typical concentrations to crop safety.
Fenbutatin oxide (Fenbutatin oxide) chemical name: two [three 2-methyl-phenyl propyl) tin] oxide, molecular formula: C
60h
78oSn
2.Fenbutatin oxide is a kind of non-interior suction miticide, to organic phosphor and organochlorine, has the harmful mite of resistance not produce cross resistance to it, and evil mite be take and tagged as main.
Fluorine mite piperazine (diflovidazin) chemical name: 3-(2-chlorphenyl)-6-(2,6-difluorophenyl)-1,2,4,5-tetrazine, molecular formula: C14H7ClF2N4.Fluorine mite piperazine can contact the ovum and active through skin that goes out, and attracts mite to become mite to take food, and also prevents and treats the mite mite in pupa stage.This compound effects mechanism is unique, not only ovum and one-tenth mite is had to excellent activity, and makes female mite produce unsound ovum, causes destroying the evidence of mite, also can prevent the evil mites such as pear sucker, oystershell scale, leafhopper simultaneously, and to natural enemy and Environmental security.
Fenisobromolate (bromopropylate) chemical name: 4,4'-dibromo diphenylglycollic acid isopropyl ester, molecular formula C
17h
16br
2o
3, fenisobromolate be a kind ofly kill that mite spectrum is wide, the lasting period is long, toxicity is low, to the safer miticide of natural enemy, honeybee and crop.Tagging property is stronger, and without interior absorption, if to becoming mite and ovum all to have certain lethal effect, variations in temperature is little on drug effect impact.
Yet in the real process of agricultural production, the problem that control evil mite the most easily produces is the drug-fast generation of evil mite.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance evil mite.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect very obviously, co-toxicity coefficient very high composite just still less.Through inventor's research, after discovery is composite by acequinocyl and clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate, can produce good synergistic effect, and not yet open about the composite relevant report of acequinocyl and clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate.
Summary of the invention
The object of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good miticide composition containing acequinocyl.
The miticide composition containing acequinocyl that the present invention proposes contains active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 80 ︰ 1, described active components A is selected from acequinocyl, active component B is selected from a kind of in clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate, and active components A and the preferred weight ratio of active component B are 1 ︰ 50 ~ 50 ︰ 1; More preferably the weight ratio of acequinocyl and clofentezine is 1 ︰ 30 ~ 30 ︰ 1, the weight ratio of acequinocyl and azacyclotin is 1 ︰ 30 ~ 15 ︰ 1, the weight ratio of acequinocyl and fenbutatin oxide is 1 ︰ 30 ~ 15 ︰ 1, the weight ratio of acequinocyl and fluorine mite piperazine is 1 ︰ 10 ~ 30 ︰ 1, and the weight ratio of acequinocyl and fenisobromolate is 1 ︰ 30 ~ 10 ︰ 1; More preferably the weight ratio of acequinocyl and clofentezine is 1 ︰ 10 ~ 10 ︰ 1, the weight ratio of acequinocyl and azacyclotin is 1 ︰ 15 ~ 5 ︰ 1, the weight ratio of acequinocyl and fenbutatin oxide is 1 ︰ 15 ~ 5 ︰ 1, the weight ratio of acequinocyl and fluorine mite piperazine is 1 ︰ 5 ~ 15 ︰ 1, and the weight ratio of acequinocyl and fenisobromolate is 1 ︰ 15 ~ 5 ︰ 1.
The miticide composition containing acequinocyl that the present invention proposes is for preventing and treating the purposes of evil mite on crops, and described crops comprise cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flowers crop, medicinal crop, raw material crop, green manure pasture crop; Described harmful mite comprises two spotted spider mite, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, beginning tetranychid, refreshing Ze Shi tetranychid.
The weight ratio of active components A, active component B is 1 ︰ 80 ~ 80 ︰ 1.Conventionally in composition, the weight percentage of active component is gross weight 0.5%～90%, is preferably 5%～80%.According to different preparation types, active component content scope is different.Conventionally, liquid preparation contains 1%～70% active substance by weight, is preferably 5%～50%; Solid pharmaceutical preparation contains 5%～80% active substance by weight, is preferably 10%～80%.
In miticide composition of the present invention, at least contain a kind of surfactant, the dispersion of active component in water while being beneficial to use.Surface-active contents is 5%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of miticide composition of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, binding agent or defoamer.According to different dosage form, in preparation, can also contain disintegrant known in those skilled in the art, antifreeze etc.
Miticide composition of the present invention can be by user before use through dilution or directly use.Its preparation can be prepared by common processing method known in those skilled in the art, after being about to active substance and mixing with liquid flux or solid carrier, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer etc.
Miticide composition of the present invention, can be processed on demand acceptable formulation on any agricultural chemicals, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
When making wetting powder, composition comprises following constituent content: active components A 1% ~ 80%, active component B1% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
When making water dispersible granules, composition comprises following constituent content: active components A 1% ~ 80%, active component B1% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
When making suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
When making suspension emulsion, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 1% ~ 15%, thickener 0 ~ 2%, emulsifier 2% ~ 12%, antifreeze 0 ~ 8%, deionized water add to 100%.
When making aqueous emulsion, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, thickener 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water are supplied surplus.
When making microemulsion, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 3% ~ 25%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water are supplied surplus.
When making microcapsule suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, organic solvent 1% ~ 10%, emulsifier 1% ~ 7%, defoamer 0.01% ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
When making microcapsule suspension-suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%;
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspending agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) acequinocyl and clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate composite after, there is obvious synergy and lasting effect; (2) the harmful mite on cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flowers crop, medicinal crop, raw material crop, green manure pasture crop is all had to greater activity; (3) reduce agricultural chemicals dosage, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution; (4), to person poultry safety, Environmental compatibility is good; And preparation adhesion strength strengthens, resistance of rainwater washing against.
Embodiment
Below in conjunction with embodiment, to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Example 1～14 wetting powder
Acequinocyl, active component B, dispersant, wetting agent, filler are mixed in mixed cylinder, after airslide disintegrating mill is pulverized, mix again, can make wetting powder product of the present invention, specifically in Table 1.
Table 1 embodiment 1～14 each component and weight portion
Example 15～28 water dispersible granules
Acequinocyl, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained to the particle diameter needing through air-flow crushing together, then add other auxiliary agents such as binding agent (can add and can not add), obtain the materials of granulating.By item quantitatively send in fluidized bed granulation dryer through granulation and dry after, can make water dispersible granules product of the present invention, specifically in Table 2.
Table 2 embodiment 15～28 each component and weight portions
Example 29～42 suspending agents
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), through high speed shear, mix, add acequinocyl, active component B, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, surplus is supplied by deionized water, can make suspending agent product of the present invention, specifically in Table 3.
Table 3 embodiment 29～42 each component and weight portions
Example 43～51 suspension emulsions
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add acequinocyl, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make acequinocyl suspending agent, then by active component B, solvent, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, surplus is supplied by deionized water, make suspension emulsion product of the present invention, specifically in Table 4,5.
Table 4 embodiment 43～48 each component and weight portions
Table 5 embodiment 49～51 each component and weight portions
Example 52～60 aqueous emulsions
Acequinocyl, active component B, solvent, emulsifier are added together, make to be dissolved into even oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, become homogeneous water.Under high-speed stirred, water is added to oil phase, surplus is supplied by deionized water; Can make aqueous emulsion product of the present invention, specifically in Table 6.
Table 6 embodiment 52～60 each component and weight portions
Clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate in table 1 ~ 6 are exchanged, can make novel formulation.
Example 61～63 microemulsions
Acequinocyl, active component B, solvent, emulsifier, antifreeze (can add and can not add), defoamer are fully mixed into the oil phase of homogeneous transparent, under agitation slowly add deionized water, form WO emulsion, again through agitating heating, make it rapid phase inversion and become oil-in-water type, be chilled to room temperature and make it to reach balance, after filtration, surplus is supplied by deionized water; Can make microemulsion product of the present invention, specifically in Table 7.
Table 7 embodiment 61～63 each component and weight portions
Example 64,65 microcapsule suspending agents
By acequinocyl, active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, under shearing condition, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent, dispersant, surplus is supplied by deionized water, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in Table 8.
Table 8 embodiment 64,65 each component and weight portions
Example 66,67 microcapsule suspensions-suspending agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent under shearing condition, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add acequinocyl, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make suspending agent, then suspending agent is joined in the aqueous phase solution of micro-capsule suspension, deionized water is supplied surplus, make the finely disseminated microcapsule suspension-suspending agent of present composition product, specifically in Table 9.
Table 9 embodiment 66,67 each component and weight portions
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.First pass through Toxicity Determination, co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are composite by a certain percentage, CTC < 80 is antagonism, 80≤CTC≤120 are summation action, CTC > 120 is synergistic effect, on this basis, then carry out field trial.
Test method: respectively the mother liquor of each mixed agent is diluted to five series concentration during test, is placed in respectively beaker standby.Adopt and first to soak the method that connects mite after leaf, after the blade of the same size that does not contact any medicament is soaked to 5s in the liquid configuring, take out, naturally dry, put into and support mite box, then connect for the young mite of examination, under 25 ℃ of conditions, raise, every processing repeats for 3 times, every to repeat examination mite number used be 50, establishes blank simultaneously, in 72h, checks dead mite number, calculate lethality and corrected mortality, try to achieve virulence regression equation and calculate LC
50value.If contrast lethality is greater than 10%, be considered as invalid test.Computing formula is as follows:
Evil mite corrected mortality is converted into probit value (y), and concentration for the treatment of (μ g/ml) converts logarithm value to (x), with method of least squares, draws virulence regression equation, and calculates thus the value of every kind of medicament, according to the abundant equation of Sun Yun, calculates co-toxicity coefficient CTC.Computing formula following (take acequinocyl as standard medicament, its toxicity index is 100):
TI * the P of theoretical toxicity index (TTI)=acequinocyl of M
acequinocyltI * P of+effective active composition B
effective active compositionb
In formula: the mixture that M is different proportionings
P
effective active compositionb is effective active composition B shared ratio in composition
P
acequinocylfor acequinocyl shared ratio in composition
B is selected from a kind of in clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate.
Application Example two:
For trying evil mite: mandarin tree two spotted spider mite
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective lethal concentration scope of determining the former medicine of acequinocyl and clofentezine and the two different proportioning mixture through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to mandarin tree two spotted spider mite of table 10 acequinocyl and clofentezine
| Reagent agent | Proportioning | LC 50(ug/mL) | Co-toxicity coefficient (CTC) |
| Acequinocyl | - | 1.65 | - |
| Clofentezine | - | 1.53 | - |
| Man Kun ︰ clofentezine goes out | 80∶1 | 0.92 | 179.17 |
| Man Kun ︰ clofentezine goes out | 50∶1 | 0.90 | 183.05 |
| Man Kun ︰ clofentezine goes out | 40∶1 | 0.85 | 193.75 |
| Man Kun ︰ clofentezine goes out | 30∶1 | 0.76 | 216.56 |
| Man Kun ︰ clofentezine goes out | 20∶1 | 0.72 | 228.31 |
| Man Kun ︰ clofentezine goes out | 10∶1 | 0.69 | 237.44 |
| Man Kun ︰ clofentezine goes out | 5∶1 | 0.66 | 246.78 |
| Man Kun ︰ clofentezine goes out | 1∶1 | 0.59 | 269.11 |
| Man Kun ︰ clofentezine goes out | 1∶5 | 0.63 | 245.84 |
| Man Kun ︰ clofentezine goes out | 1∶10 | 0.66 | 233.37 |
| Man Kun ︰ clofentezine goes out | 1∶20 | 0.69 | 222.52 |
| Man Kun ︰ clofentezine goes out | 1∶30 | 0.70 | 219.09 |
| Man Kun ︰ clofentezine goes out | 1∶40 | 0.79 | 194.02 |
| Man Kun ︰ clofentezine goes out | 1∶50 | 0.82 | 186.86 |
| Man Kun ︰ clofentezine goes out | 1∶80 | 0.87 | 176.03 |
As shown in Table 10, acequinocyl and clofentezine to mandarin tree two spotted spider mite proportioning when 1 ︰ 80 ~ 80 ︰ 1, co-toxicity coefficient is all greater than 120, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of acequinocyl and clofentezine is during at 1 ︰ 30 ~ 30 ︰ 1, synergistic effect is more obviously outstanding, and co-toxicity coefficient is all greater than 215.Wherein when acequinocyl and clofentezine weight ratio are 1:1, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.Through applicant, test and find that acequinocyl and clofentezine proportioning are 30:1, 25:1, 20:1, 15:1, 10:1, 8:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:8, 1:10, 1:12, 1:14, 1:15, 1:20, 1:25, during 1:30 to the two spotted spider mite in various crop, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, beginning tetranychid, the control of god Ze Shi tetranychid has obvious synergistic effect, co-toxicity coefficient is all greater than 120.
Application Example three
For trying evil mite: European red mite
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective lethal concentration scope of determining the former medicine of acequinocyl and azacyclotin and the two different proportioning mixture through preliminary experiment.
The composite toxicity test analysis of results table to European red mite of table 11 acequinocyl and azacyclotin
| Reagent agent | Proportioning | LC 50(ug/mL) | Co-toxicity coefficient (CTC) |
| Acequinocyl | - | 1.52 | - |
| Azacyclotin | - | 2.98 | - |
| Man Kun ︰ azacyclotin goes out | 80∶1 | 0.86 | 177.82 |
| Man Kun ︰ azacyclotin goes out | 50∶1 | 0.81 | 189.47 |
| Man Kun ︰ azacyclotin goes out | 30∶1 | 0.80 | 193.05 |
| Man Kun ︰ azacyclotin goes out | 15∶1 | 0.74 | 211.89 |
| Man Kun ︰ azacyclotin goes out | 10∶1 | 0.71 | 224.07 |
| Man Kun ︰ azacyclotin goes out | 5∶1 | 0.70 | 236.45 |
| Man Kun ︰ azacyclotin goes out | 1∶2 | 0.84 | 268.74 |
| Man Kun ︰ azacyclotin goes out | 1∶8 | 1.09 | 247.06 |
| Man Kun ︰ azacyclotin goes out | 1∶15 | 1.20 | 234.30 |
| Man Kun ︰ azacyclotin goes out | 1∶30 | 1.35 | 214.13 |
| Man Kun ︰ azacyclotin goes out | 1∶40 | 1.50 | 194.14 |
| Man Kun ︰ azacyclotin goes out | 1∶50 | 1.61 | 181.69 |
| Man Kun ︰ azacyclotin goes out | 1∶80 | 1.68 | 175.32 |
As shown in Table 11, acequinocyl and azacyclotin to European red mite proportioning when 1 ︰ 80 ~ 80 ︰ 1, co-toxicity coefficient is all greater than 120, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of acequinocyl and azacyclotin is during at 1 ︰ 30 ~ 15 ︰ 1, synergistic effect is more obviously outstanding, and co-toxicity coefficient is all greater than 210.Wherein when acequinocyl and azacyclotin weight ratio are 1:2, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.Through applicant test while finding that acequinocyl and azacyclotin proportioning are 15:1,10:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:12,1:14,1:15,1:20,1:25,1:30 to the two spotted spider mite in various crop, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, beginning tetranychid, refreshing Ze Shi tetranychid control have obvious synergistic effect, co-toxicity coefficient is all greater than 120.
Application Example four
For trying evil mite: cotton red spider
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective lethal concentration scope of determining the former medicine of acequinocyl and fenbutatin oxide and the two different proportioning mixture through preliminary experiment.
The composite toxicity test analysis of results table to cotton red spider of table 12 acequinocyl and fenbutatin oxide
As shown in Table 12, acequinocyl and fenbutatin oxide to cotton red spider proportioning when 1 ︰ 80 ~ 80 ︰ 1, co-toxicity coefficient is all greater than 120, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of acequinocyl and fenbutatin oxide is during at 1 ︰ 30 ~ 15 ︰ 1, synergistic effect is more obviously outstanding, and co-toxicity coefficient is all greater than 215.Wherein when acequinocyl and fenbutatin oxide weight ratio are 1:2, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.Through applicant, test while finding that acequinocyl and fenbutatin oxide proportioning are 15:1,10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:25,1:30, to the two spotted spider mite in various crop, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, beginning, the control of tetranychid, refreshing Ze Shi tetranychid has obvious synergistic effect, and co-toxicity coefficient is all greater than 120.
Application Example five
For trying evil mite: apple Tetranychus urticae
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective lethal concentration scope of determining acequinocyl and the former medicine of fluorine mite piperazine and the two different proportioning mixture through preliminary experiment.
The composite toxicity test analysis of results table to apple Tetranychus urticae of table 13 acequinocyl and fluorine mite piperazine
| Reagent agent | Proportioning | LC 50(ug/mL) | Co-toxicity coefficient (CTC) |
| Acequinocyl | - | 1.61 | - |
| Fluorine mite piperazine | - | 0.52 | - |
| Man Kun ︰ fluorine mite piperazine goes out | 80∶1 | 0.89 | 176.54 |
| Man Kun ︰ fluorine mite piperazine goes out | 50∶1 | 0.82 | 188.93 |
| Man Kun ︰ fluorine mite piperazine goes out | 40∶1 | 0.79 | 194.32 |
| Man Kun ︰ fluorine mite piperazine goes out | 30∶1 | 0.68 | 222.42 |
| Man Kun ︰ fluorine mite piperazine goes out | 15∶1 | 0.62 | 230.82 |
| Man Kun ︰ fluorine mite piperazine goes out | 8∶1 | 0.54 | 243.94 |
| Man Kun ︰ fluorine mite piperazine goes out | 4∶1 | 0.45 | 255.56 |
| Man Kun ︰ fluorine mite piperazine goes out | 1∶1 | 0.33 | 243.94 |
| Man Kun ︰ fluorine mite piperazine goes out | 1∶5 | 0.26 | 232.21 |
| Man Kun ︰ fluorine mite piperazine goes out | 1∶10 | 0.25 | 228.52 |
| Man Kun ︰ fluorine mite piperazine goes out | 1∶20 | 0.27 | 205.28 |
| Man Kun ︰ fluorine mite piperazine goes out | 1∶40 | 0.28 | 194.83 |
| Man Kun ︰ fluorine mite piperazine goes out | 1∶50 | 0.30 | 181.26 |
| Man Kun ︰ fluorine mite piperazine goes out | 1∶80 | 0.31 | 174.55 |
As shown in Table 13, acequinocyl and fluorine mite piperazine to apple Tetranychus urticae proportioning when 1 ︰ 80 ~ 80 ︰ 1, co-toxicity coefficient is all greater than 120, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of acequinocyl and fluorine mite piperazine is during at 1 ︰ 10 ~ 30 ︰ 1, synergistic effect is more obviously outstanding, and co-toxicity coefficient is all greater than 220, wherein when acequinocyl and fluorine mite piperazine weight ratio are 4:1, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.Through applicant test while finding that acequinocyl and fluorine mite piperazine proportioning are 10:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:12,1:14,1:15,1:20,1:25,1:30 to the two spotted spider mite in various crop, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, beginning tetranychid, refreshing Ze Shi tetranychid control have obvious synergistic effect, co-toxicity coefficient is all greater than 120.
Application Example six
For trying evil mite: apple tree two spotted spider mite
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective lethal concentration scope of determining the former medicine of acequinocyl and fenisobromolate and the two different proportioning mixture through preliminary experiment.
The composite toxicity test analysis of results table to apple tree two spotted spider mite of table 14 acequinocyl and fenisobromolate
| Reagent agent | Proportioning | LC 50(ugmL) | Co-toxicity coefficient (CTC) |
| Acequinocyl | - | 1.49 | - |
| Fenisobromolate | - | 4.15 | - |
| Man Kun ︰ fenisobromolate goes out | 80∶1 | 0.88 | 170.67 |
| Man Kun ︰ fenisobromolate goes out | 50∶1 | 0.86 | 175.46 |
| Man Kun ︰ fenisobromolate goes out | 40∶1 | 0.80 | 189.21 |
| Man Kun ︰ fenisobromolate goes out | 20∶1 | 0.78 | 197.04 |
| Man Kun ︰ fenisobromolate goes out | 10∶1 | 0.72 | 219.75 |
| Man Kun ︰ fenisobromolate goes out | 5∶1 | 0.74 | 225.44 |
| Man Kun ︰ fenisobromolate goes out | 1∶1 | 0.89 | 246.38 |
| Man Kun ︰ fenisobromolate goes out | 1∶3 | 1.10 | 260.87 |
| Man Kun ︰ fenisobromolate goes out | 1∶8 | 1.39 | 249.16 |
| Man Kun ︰ fenisobromolate goes out | 1∶15 | 1.64 | 227.67 |
| Man Kun ︰ fenisobromolate goes out | 1∶30 | 1.81 | 216.82 |
| Man Kun ︰ fenisobromolate goes out | 1∶40 | 2.04 | 194.96 |
| Man Kun ︰ fenisobromolate goes out | 1∶50 | 2.13 | 188.26 |
| Man Kun ︰ fenisobromolate goes out | 1∶80 | 2.28 | 178.11 |
As shown in Table 14, acequinocyl and fenisobromolate to apple tree two spotted spider mite proportioning when 1 ︰ 80 ~ 80 ︰ 1, co-toxicity coefficient is all greater than 120, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of acequinocyl and fenisobromolate is during at 1 ︰ 30 ~ 10 ︰ 1, synergistic effect is more obviously outstanding, and co-toxicity coefficient is all greater than 215, wherein when acequinocyl and fenisobromolate weight ratio are 1:3, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.Through applicant test while finding that acequinocyl and fenisobromolate proportioning are 10:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:12,1:14,1:15,1:20,1:25,1:30 to the two spotted spider mite in various crop, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, beginning tetranychid, refreshing Ze Shi tetranychid control have obvious synergistic effect, co-toxicity coefficient is all greater than 120.
Effect experiment part: test medicine is researched and developed, provided by Shaanxi Mei Bang agricultural chemicals Co., Ltd, contrast medicament 15% acequinocyl suspending agent (autogamy), 20% clofentezine suspension agent (commercial), 25% azacyclotin wetting powder (commercial), 25% fenbutatin oxide suspending agent (commercial), 10% fluorine mite piperazine suspending agent (autogamy), 500 grams per liter fenisobromolate missible oil (commercial).
Application Example seven acequinocyls and active component B and the composite control mandarin tree two spotted spider mite test of pesticide effectiveness thereof, this test arrangement is in Hanzhong City suburb, Shaanxi Province, investigation mandarin tree two spotted spider mite damage index of spider mites before medicine, in the dispenser of mite evil initial stage of origination, within after dispenser 3 days, 15 days, 30 days, investigate damage index of spider mites and calculate preventive effect.Result of the test is as follows:
Table 15 acequinocyl and active component B and the composite control mandarin tree two spotted spider mite test of pesticide effectiveness thereof
As can be seen from Table 15, after acequinocyl and active component B are composite, can effectively prevent and treat mandarin tree two spotted spider mite, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example eight acequinocyls and active component B and the composite control apple tree tetranychus viennensis test of pesticide effectiveness thereof, this test arrangement is in Weinan City Dengcheng County, Shaanxi Province, investigation apple tree tetranychus viennensis damage index of spider mites before medicine, in the dispenser of mite evil initial stage of origination, within after dispenser 5 days, 20 days, 45 days, investigate damage index of spider mites and calculate preventive effect.Result of the test is as follows:
Table 16 acequinocyl and active component B and the composite control apple tree tetranychus viennensis test of pesticide effectiveness thereof
As can be seen from Table 16, energy effectively preventing and treating apple-tree tetranychus viennensis after acequinocyl and active component B are composite, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine acequinocyls and active component B and the composite control tomato goitre mite test of pesticide effectiveness thereof, this test arrangement is at Xian District, Shanxi Province suburban area, before medicine, investigation tomato goitre mite damage index of spider mites, in the dispenser of mite evil initial stage of origination, investigates damage index of spider mites and calculates preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 17 acequinocyl and active component B and the composite control tomato goitre mite test of pesticide effectiveness thereof
As can be seen from Table 17, acequinocyl and active component B and composite control tomato goitre mite thereof, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten acequinocyls and active component B and the composite control mandarin tree Panonychus citri test of pesticide effectiveness thereof, this test arrangement is in Hanzhong City suburb, Shaanxi Province, investigation mandarin tree Panonychus citri damage index of spider mites before medicine, in the dispenser of mite evil initial stage of origination, within after dispenser 3 days, 15 days, 30 days, investigate damage index of spider mites and calculate preventive effect.Result of the test is as follows:
Table 18 acequinocyl and active component B and the composite control mandarin tree Panonychus citri test of pesticide effectiveness thereof
As can be seen from Table 18, after acequinocyl and active component B are composite, can effectively prevent and treat mandarin tree Panonychus citri, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 acequinocyls and active component B and the composite control cotton red spider test of pesticide effectiveness thereof, this test arrangement is in Weinan City Dali County, Shaanxi Province, investigation cotton red spider damage index of spider mites before medicine, in the dispenser of mite evil initial stage of origination, within after dispenser 3 days, 15 days, 30 days, investigate damage index of spider mites and calculate preventive effect.Result of the test is as follows:
Table 19 acequinocyl and active component B and the composite control cotton red spider test of pesticide effectiveness thereof
As can be seen from Table 19, after acequinocyl and active component B are composite, can effectively prevent and treat cotton red spider, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 12 acequinocyls and active component B and the composite control yellow tea mite test of pesticide effectiveness thereof, this test arrangement is in suburb, Ya'an, Sichuan Province, investigation yellow tea mite damage index of spider mites before medicine, in the dispenser of mite evil initial stage of origination, investigates damage index of spider mites and calculates preventive effect for after dispenser 3 days, 10 days, 20 days.Result of the test is as follows:
Table 20 acequinocyl and active component B and the composite control yellow tea mite test of pesticide effectiveness thereof
As can be seen from Table 20, after acequinocyl and active component B are composite, can effectively prevent and treat yellow tea mite, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After through different local throughout the country tests, draw, acequinocyl and clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate composite rear to the preventive effect of common harmful mite such as the two spotted spider mite in various crop, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, beginning tetranychid, refreshing Ze Shi tetranychid etc. all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the miticide composition containing acequinocyl, contain active components A and active component B, it is characterized in that: active components A and active component B weight ratio are 1 ︰ 80 ~ 80 ︰ 1, described active components A is selected from acequinocyl, and active component B is selected from a kind of in clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate.
2. the miticide composition containing acequinocyl according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 50 ~ 50 ︰ 1.
3. the miticide composition containing acequinocyl according to claim 2, is characterized in that:
The weight ratio of acequinocyl and clofentezine is 1 ︰ 30 ~ 30 ︰ 1;
The weight ratio of acequinocyl and azacyclotin is 1 ︰ 30 ~ 15 ︰ 1;
The weight ratio of acequinocyl and fenbutatin oxide is 1 ︰ 30 ~ 15 ︰ 1;
The weight ratio of acequinocyl and fluorine mite piperazine is 1 ︰ 10 ~ 30 ︰ 1;
The weight ratio of acequinocyl and fenisobromolate is 1 ︰ 30 ~ 10 ︰ 1.
4. according to the miticide composition containing acequinocyl described in any one in claims 1 to 3, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
5. the miticide composition containing acequinocyl according to claim 4 is for preventing and treating the purposes of evil mite on crops.
6. purposes according to claim 5, is characterized in that, described harmful mite comprises: two spotted spider mite, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, beginning tetranychid, refreshing Ze Shi tetranychid.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210215651.3A CN103503911B (en) | 2012-06-27 | 2012-06-27 | A kind of miticide composition containing acequinocyl |
| CN201510562455.7A CN105165882B (en) | 2012-06-27 | 2012-06-27 | A kind of miticide composition containing acequinocyl |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210215651.3A CN103503911B (en) | 2012-06-27 | 2012-06-27 | A kind of miticide composition containing acequinocyl |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510562455.7A Division CN105165882B (en) | 2012-06-27 | 2012-06-27 | A kind of miticide composition containing acequinocyl |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103503911A true CN103503911A (en) | 2014-01-15 |
| CN103503911B CN103503911B (en) | 2015-12-16 |
Family
ID=49887770
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210215651.3A Expired - Fee Related CN103503911B (en) | 2012-06-27 | 2012-06-27 | A kind of miticide composition containing acequinocyl |
| CN201510562455.7A Expired - Fee Related CN105165882B (en) | 2012-06-27 | 2012-06-27 | A kind of miticide composition containing acequinocyl |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510562455.7A Expired - Fee Related CN105165882B (en) | 2012-06-27 | 2012-06-27 | A kind of miticide composition containing acequinocyl |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN103503911B (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10013914A1 (en) * | 2000-03-21 | 2001-09-27 | Bayer Ag | Synergistic pesticidal composition comprising 4-hydroxy-3-phenyl-furan-2(5H)-one derivative and bifenazate, abamectin or bifenthrin, are useful as insecticide, acaricide, ectoparasiticide or antifouling agents |
| DE10353281A1 (en) * | 2003-11-14 | 2005-06-16 | Bayer Cropscience Ag | Combination of active ingredients with insecticidal and acaricidal properties |
| JP5091470B2 (en) * | 2006-12-05 | 2012-12-05 | クミアイ化学工業株式会社 | Agricultural and horticultural compositions |
| CN101884331A (en) * | 2010-07-08 | 2010-11-17 | 东莞市瑞德丰生物科技有限公司 | Synergistic mite killing composition |
-
2012
- 2012-06-27 CN CN201210215651.3A patent/CN103503911B/en not_active Expired - Fee Related
- 2012-06-27 CN CN201510562455.7A patent/CN105165882B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN105165882A (en) | 2015-12-23 |
| CN103503911B (en) | 2015-12-16 |
| CN105165882B (en) | 2017-07-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103563901A (en) | High-efficient insecticide composition containing propylene glycol alginate | |
| CN103907612B (en) | Pyriminostrobin-containing insecticidal composition | |
| CN103563899B (en) | High-efficient pesticide composition | |
| CN103380783B (en) | A kind of high-efficient pesticide composition | |
| CN103563963A (en) | Insecticidal composition containing propylene glycol alginate | |
| CN103907624A (en) | Pyriminostrobin-containing acaricidal composition | |
| CN103931641A (en) | Insecticidal composition containing silvchongxian'an and carbamate | |
| CN103651363A (en) | Pesticidal composition containing spiromesifen and nereistoxin | |
| CN103907630B (en) | A kind of miticide composition containing phonetic mite amine | |
| CN103907623B (en) | A kind of High-efficiency miticidal composition containing phonetic mite amine | |
| CN103503874A (en) | Pesticide combination containing acequinocyl | |
| CN103891761B (en) | A kind of compound acaricide composition containing phonetic mite amine | |
| CN103503911B (en) | A kind of miticide composition containing acequinocyl | |
| CN103416407B (en) | A kind of composition pesticide | |
| CN103621524A (en) | Pesticide composition | |
| CN103931620A (en) | Insecticidal composition containing silvchongxian'an and nereistoxin insecticide | |
| CN104115830A (en) | Insecticidal composition containing flubendiamide and nereistoxin | |
| CN104585216A (en) | Acaricidal composition containing pyriminostrobin | |
| CN103416408A (en) | Insecticidal combination containing fluacrypyrim | |
| CN103503902B (en) | A kind of High-efficiency miticidal composition | |
| CN103503877B (en) | A kind of composition pesticide | |
| CN103503876A (en) | Insecticidal composition containing bromantraniliprole and nereistoxin | |
| CN104686521A (en) | Anti-mite composition containing pyriminostrobin | |
| CN103621528B (en) | High efficient mite-killing composition | |
| CN103385252A (en) | Pesticide composition comprising fluacrypyrim |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151216 Termination date: 20180627 |