CN103503911B - A kind of miticide composition containing acequinocyl - Google Patents
A kind of miticide composition containing acequinocyl Download PDFInfo
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- CN103503911B CN103503911B CN201210215651.3A CN201210215651A CN103503911B CN 103503911 B CN103503911 B CN 103503911B CN 201210215651 A CN201210215651 A CN 201210215651A CN 103503911 B CN103503911 B CN 103503911B
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Abstract
The invention discloses a kind of miticide composition containing acequinocyl, miticide composition containing active components A and active component B, wherein active components A is selected from acequinocyl, active component B is selected from any one compound following: clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate, and the weight ratio of active components A and active component B is 1 ︰ 80 ~ 80 ︰ 1.The multiple harmful mite of the present composition to harm agricultural production has synergistic effect, decreases pesticide usage amount, and reduce agricultural chemicals and stay residual on crop, alleviate environmental pollution, to person poultry safety, Environmental compatibility is good, and evil mite not easily develops immunity to drugs.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of miticide composition on crops evil mite containing acequinocyl.
Background technology
Acequinocyl (acequinocyl) chemical name: 2-(acetoxyl group) 3-dodecyl-1,4-naphthoquinone, molecular formula: C
24h
32o
4.Acequinocyl is naphthoquinone derivatives, is mainly contact killing type miticide, has toxicity of ingesting concurrently.In mite body, be hydrolyzed into 2-dodecyl-3-hydroxyl-1,4-naphthoquinone, and combine with the Qo site on the electron transfer pathways in mitochondria, thus suppress electron transmission.
Clofentezine (Clofentezine) chemical name: 3,6-two (2-chlorphenyl)-1,2,4,5-tetrazine, molecular formula: C
14h
8c
12n
4.Clofentezine is special efficacy miticide, lasting medicine.If to the ovum of the panonychus ulmi occurred on fruit tree, cotton, ornamental plants, congo red spider and mite effective, harmless to Predatory Mites, natural enemy.
Azacyclotin (Azocyclotin) chemical name: 1-(thricyclohexyl stannyl)-1-hydrogen-1,2,4-triazole, molecular formula: C20H35N3Sn.Azacyclotin is the stronger broad spectrum activity miticide of action of contace poison, if can kill mite, become mite and summer egg, invalid to winter egg.Have good stability to light and rainwater, the longevity of residure is longer.To crop safety under typical concentrations.
Fenbutatin oxide (Fenbutatinoxide) chemical name: two [three 2-methylphenyl propyl group) tin] oxide, molecular formula: C
60h
78oSn
2.Fenbutatin oxide is a kind of non-interior suction miticide, has the harmful mite of resistance not produce cross resistance to it to organic phosphor and organochlorine, to evil mite to tag.
Fluorine mite piperazine (diflovidazin) chemical name: 3-(2-chlorphenyl)-6-(2,6-difluorophenyl)-1,2,4,5-tetrazines, molecular formula: C14H7ClF2N4.Fluorine mite piperazine can contact the ovum and active through skin of going out, and attracts mite to become mite to take food, also prevents and treats the mite mite in pupa stage.This compound effects mechanism is unique, not only has excellent activity to ovum and one-tenth mite, and makes female mite produce unsound ovum, cause destroying the evidence of mite, also can prevent the evil such as pear sucker, oystershell scale, leafhopper mite simultaneously, and to natural enemy and Environmental security.
Fenisobromolate (bromopropylate) chemical name: 4,4'-dibromo benzoin isopropyl propionate, molecular formula C
17h
16br
2o
3, fenisobromolate a kind ofly kills that mite spectrum is wide, the lasting period is long, toxicity is low, to the safer miticide of natural enemy, honeybee and crop.Contact comparatively strong, without interior absorption, if all have certain lethal effect to one-tenth mite and ovum, variations in temperature is little on drug effect impact.
But in the real process of agricultural production, the problem that control evil mite the most easily produces is the drug-fast generation of evil mite.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance evil mite.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of co-toxicity coefficient.Study through inventor, find acequinocyl and clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate is composite after can produce good synergistic effect, and not yet open about the relevant report that acequinocyl and clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate are composite.
Summary of the invention
The object of the invention is to propose a kind of to there is the miticide composition containing acequinocyl that synergistic function, use cost are low, preventive effect is good.
The miticide composition containing acequinocyl that the present invention proposes contains active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 80 ︰ 1, described active components A is selected from acequinocyl, active component B is selected from the one in clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate, and active components A and the preferred weight ratio of active component B are 1 ︰ 50 ~ 50 ︰ 1; The weight ratio being more preferably acequinocyl and clofentezine is 1 ︰ 30 ~ 30 ︰ 1, the weight ratio of acequinocyl and azacyclotin is 1 ︰ 30 ~ 15 ︰ 1, the weight ratio of acequinocyl and fenbutatin oxide is 1 ︰ 30 ~ 15 ︰ 1, the weight ratio of acequinocyl and fluorine mite piperazine is 1 ︰ 10 ~ 30 ︰ 1, and the weight ratio of acequinocyl and fenisobromolate is 1 ︰ 30 ~ 10 ︰ 1; The weight ratio being more preferably acequinocyl and clofentezine is 1 ︰ 10 ~ 10 ︰ 1, the weight ratio of acequinocyl and azacyclotin is 1 ︰ 15 ~ 5 ︰ 1, the weight ratio of acequinocyl and fenbutatin oxide is 1 ︰ 15 ~ 5 ︰ 1, the weight ratio of acequinocyl and fluorine mite piperazine is 1 ︰ 5 ~ 15 ︰ 1, and the weight ratio of acequinocyl and fenisobromolate is 1 ︰ 15 ~ 5 ︰ 1.
The miticide composition containing acequinocyl that the present invention proposes is for preventing and treating the purposes of evil mite on crops, and described crops comprise cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; Described harmful mite comprise two spotted spider mite, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, the beginning tetranychid, Shenmu-Yanan railway.
The weight ratio of active components A, active component B is 1 ︰ 80 ~ 80 ︰ 1.In usual composition, the weight percentage of active component is 0.5% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Usually, liquid preparation contains the active substance of by weight 1% ~ 70%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in miticide composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Surfactant selected by miticide composition of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, binding agent or defoamer.According to different dosage form, in preparation, disintegrant known in those skilled in the art, antifreeze etc. can also be contained.
Miticide composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by common processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active substance, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer etc.
Miticide composition of the present invention, can be processed into acceptable formulation on any agricultural chemicals on demand, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
Composition comprises following constituent content when making wetting powder: active components A 1% ~ 80%, active component B1% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
Composition comprises following constituent content when making water dispersible granules: active components A 1% ~ 80%, active component B1% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following constituent content when making suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following constituent content when making suspension emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 1% ~ 15%, thickener 0 ~ 2%, emulsifier 2% ~ 12%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following constituent content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, thickener 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water supply surplus.
Composition comprises following constituent content when making microemulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 3% ~ 25%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water supply surplus.
Composition comprises following constituent content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, organic solvent 1% ~ 10%, emulsifier 1% ~ 7%, defoamer 0.01% ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Composition comprises following constituent content when making microcapsule suspension-suspendinagent agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%;
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) acequinocyl and clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate composite after, there is obvious synergy and lasting effect; (2) all greater activity is had to the harmful mite on cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; (3) decrease pesticide usage amount, reduce the residual quantity of agricultural chemicals on crop, alleviate environmental pollution; (4) to person poultry safety, Environmental compatibility is good; And preparation adhesion strength strengthens, resistance of rainwater washing against.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Example 1 ~ 14 wetting powder
Acequinocyl, active component B, dispersant, wetting agent, filler are mixed in mixed cylinder, mixes again after airslide disintegrating mill is pulverized, wetting powder product of the present invention can be obtained, specifically in table 1.
The each component of table 1 embodiment 1 ~ 14 and weight portion
Example 15 ~ 28 water dispersible granules
Acequinocyl, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent (can add and can not add), obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, water dispersible granules product of the present invention can being obtained, specifically in table 2.
The each component of table 2 embodiment 15 ~ 28 and weight portion
Example 29 ~ 42 suspending agent
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), mix through high speed shear, add acequinocyl, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can obtain suspending agent product of the present invention, specifically in table 3.
The each component of table 3 embodiment 29 ~ 42 and weight portion
Example 43 ~ 51 suspension emulsion
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add acequinocyl, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained acequinocyl suspending agent, then by active component B, solvent, emulsifier and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, surplus deionized water is supplied, obtained suspension emulsion product of the present invention, specifically in table 4,5.
The each component of table 4 embodiment 43 ~ 48 and weight portion
The each component of table 5 embodiment 49 ~ 51 and weight portion
Example 52 ~ 60 aqueous emulsion
Acequinocyl, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, surplus deionized water is supplied; Aqueous emulsion product of the present invention can be obtained, specifically in table 6.
The each component of table 6 embodiment 52 ~ 60 and weight portion
Clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate in table 1 ~ 6 are exchanged, can novel formulation be obtained.
Example 61 ~ 63 microemulsion
Acequinocyl, active component B, solvent, emulsifier, antifreeze (can add and can not add), defoamer are fully mixed into the oil phase of homogeneous transparent, under agitation slowly add deionized water, form WO emulsion, again through agitating heating, make it rapid phase inversion and become oil-in-water type, be chilled to room temperature to make it to reach balance, after filtration, surplus deionized water is supplied; Microemulsion product of the present invention can be obtained, specifically in table 7.
The each component of table 7 embodiment 61 ~ 63 and weight portion
Example 64,65 microcapsule suspending agent
By acequinocyl, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 8.
Table 8 embodiment 64,65 each component and weight portion
Example 66,67 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add acequinocyl, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, make the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition, specifically in table 9.
Table 9 embodiment 66,67 each component and weight portion
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First pass through Toxicity Determination, co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are composite by a certain percentage, CTC < 80 is antagonism, 80≤CTC≤120 are summation action, CTC > 120 is synergistic effect, on this basis, then carry out field trial.
Test method: respectively the mother liquor of each mixed agent is diluted to five series concentration during test, is placed in beaker respectively for subsequent use.Adopt the method connecing mite after first soaking leaf, take out after the blade of the same size not contacting any medicament is soaked 5s in the liquid configured, naturally dry, put into foster mite box, then connect for the young mite of examination, raise under 25 DEG C of conditions, often process and repeat for 3 times, often repeating examination mite number used is 50, establishes blank simultaneously, checks dead mite number in 72h, calculate lethality and corrected mortality, try to achieve virulence regression equation and calculate LC
50value.If contrast lethality is greater than 10%, be then considered as invalid test.Computing formula is as follows:
Evil mite corrected mortality is converted into probit value (y), and concentration for the treatment of (μ g/ml) converts logarithm value to (x), draws virulence regression equation, and calculate the value of often kind of medicament thus with method of least squares, calculates co-toxicity coefficient CTC according to the abundant equation of Sun Yun.Computing formula following (take acequinocyl as standard agent, its toxicity index is 100):
TI × the P of theoretical toxicity index (the TTI)=acequinocyl of M
acequinocyltI × the P of+effective active composition B
effective active compositionb
In formula: M is the mixture of different ratio
P
effective active compositionb is the shared in the composition ratio of effective active composition B
P
acequinocylfor the ratio that acequinocyl is shared in the composition
B is selected from the one in clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate.
Application Example two:
For examination evil mite: mandarin tree two spotted spider mite
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective lethal concentration scope of preliminary experiment determination acequinocyl and the former medicine of clofentezine and the two different ratio mixture.
Toxicity test result
Table 10 acequinocyl and the composite toxicity test analysis of results table to mandarin tree two spotted spider mite of clofentezine
| Reagent agent | Proportioning | LC 50(ug/mL) | Co-toxicity coefficient (CTC) |
| Acequinocyl | - | 1.65 | - |
| Clofentezine | - | 1.53 | - |
| Go out Man Kun ︰ clofentezine | 80∶1 | 0.92 | 179.17 |
| Go out Man Kun ︰ clofentezine | 50∶1 | 0.90 | 183.05 |
| Go out Man Kun ︰ clofentezine | 40∶1 | 0.85 | 193.75 |
| Go out Man Kun ︰ clofentezine | 30∶1 | 0.76 | 216.56 |
| Go out Man Kun ︰ clofentezine | 20∶1 | 0.72 | 228.31 |
| Go out Man Kun ︰ clofentezine | 10∶1 | 0.69 | 237.44 |
| Go out Man Kun ︰ clofentezine | 5∶1 | 0.66 | 246.78 |
| Go out Man Kun ︰ clofentezine | 1∶1 | 0.59 | 269.11 |
| Go out Man Kun ︰ clofentezine | 1∶5 | 0.63 | 245.84 |
| Go out Man Kun ︰ clofentezine | 1∶10 | 0.66 | 233.37 |
| Go out Man Kun ︰ clofentezine | 1∶20 | 0.69 | 222.52 |
| Go out Man Kun ︰ clofentezine | 1∶30 | 0.70 | 219.09 |
| Go out Man Kun ︰ clofentezine | 1∶40 | 0.79 | 194.02 |
| Go out Man Kun ︰ clofentezine | 1∶50 | 0.82 | 186.86 |
| Go out Man Kun ︰ clofentezine | 1∶80 | 0.87 | 176.03 |
As shown in Table 10, acequinocyl and clofentezine to mandarin tree two spotted spider mite proportioning when 1 ︰ 80 ~ 80 ︰ 1, co-toxicity coefficient is all greater than 120, both explanations mixture in 1 ︰ 80 ~ 80 ︰ 1 scope all shows synergistic effect, when the proportioning of acequinocyl and clofentezine is at 1 ︰ 30 ~ 30 ︰ 1, synergistic effect is more obviously given prominence to, and co-toxicity coefficient is all greater than 215.Wherein when acequinocyl and clofentezine weight ratio are 1:1, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.Test through applicant and find that acequinocyl and clofentezine proportioning are 30:1, 25:1, 20:1, 15:1, 10:1, 8:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:8, 1:10, 1:12, 1:14, 1:15, 1:20, 1:25, to the two spotted spider mite in various crop during 1:30, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, beginning tetranychid, the control of Shenmu-Yanan railway has obvious synergistic effect, co-toxicity coefficient is all greater than 120.
Application Example three
For examination evil mite: European red mite
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective lethal concentration scope of preliminary experiment determination acequinocyl and the former medicine of azacyclotin and the two different ratio mixture.
Table 11 acequinocyl and the composite toxicity test analysis of results table to European red mite of azacyclotin
| Reagent agent | Proportioning | LC 50(ug/mL) | Co-toxicity coefficient (CTC) |
| Acequinocyl | - | 1.52 | - |
| Azacyclotin | - | 2.98 | - |
| Go out Man Kun ︰ azacyclotin | 80∶1 | 0.86 | 177.82 |
| Go out Man Kun ︰ azacyclotin | 50∶1 | 0.81 | 189.47 |
| Go out Man Kun ︰ azacyclotin | 30∶1 | 0.80 | 193.05 |
| Go out Man Kun ︰ azacyclotin | 15∶1 | 0.74 | 211.89 |
| Go out Man Kun ︰ azacyclotin | 10∶1 | 0.71 | 224.07 |
| Go out Man Kun ︰ azacyclotin | 5∶1 | 0.70 | 236.45 |
| Go out Man Kun ︰ azacyclotin | 1∶2 | 0.84 | 268.74 |
| Go out Man Kun ︰ azacyclotin | 1∶8 | 1.09 | 247.06 |
| Go out Man Kun ︰ azacyclotin | 1∶15 | 1.20 | 234.30 |
| Go out Man Kun ︰ azacyclotin | 1∶30 | 1.35 | 214.13 |
| Go out Man Kun ︰ azacyclotin | 1∶40 | 1.50 | 194.14 |
| Go out Man Kun ︰ azacyclotin | 1∶50 | 1.61 | 181.69 |
| Go out Man Kun ︰ azacyclotin | 1∶80 | 1.68 | 175.32 |
As shown in Table 11, acequinocyl and azacyclotin to European red mite proportioning when 1 ︰ 80 ~ 80 ︰ 1, co-toxicity coefficient is all greater than 120, both explanations mixture in 1 ︰ 80 ~ 80 ︰ 1 scope all shows synergistic effect, when the proportioning of acequinocyl and azacyclotin is at 1 ︰ 30 ~ 15 ︰ 1, synergistic effect is more obviously given prominence to, and co-toxicity coefficient is all greater than 210.Wherein when acequinocyl and azacyclotin weight ratio are 1:2, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.Through applicant test find that acequinocyl and azacyclotin proportioning are 15:1,10:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:12,1:14,1:15,1:20,1:25,1:30 time to the two spotted spider mite in various crop, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, the beginning tetranychid, Shenmu-Yanan railway control have obvious synergistic effect, co-toxicity coefficient is all greater than 120.
Application Example four
For examination evil mite: cotton red spider
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective lethal concentration scope of preliminary experiment determination acequinocyl and the former medicine of fenbutatin oxide and the two different ratio mixture.
Table 12 acequinocyl and the composite toxicity test analysis of results table to cotton red spider of fenbutatin oxide
As shown in Table 12, acequinocyl and fenbutatin oxide to cotton red spider proportioning when 1 ︰ 80 ~ 80 ︰ 1, co-toxicity coefficient is all greater than 120, both explanations mixture in 1 ︰ 80 ~ 80 ︰ 1 scope all shows synergistic effect, when the proportioning of acequinocyl and fenbutatin oxide is at 1 ︰ 30 ~ 15 ︰ 1, synergistic effect is more obviously given prominence to, and co-toxicity coefficient is all greater than 215.Wherein when acequinocyl and fenbutatin oxide weight ratio are 1:2, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.When applicant tests discovery acequinocyl and fenbutatin oxide proportioning is 15:1,10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:25,1:30, to the two spotted spider mite in various crop, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, the beginning tetranychid, Shenmu-Yanan railway control have obvious synergistic effect, co-toxicity coefficient is all greater than 120.
Application Example five
For examination evil mite: apple Tetranychus urticae
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective lethal concentration scope of preliminary experiment determination acequinocyl and the former medicine of fluorine mite piperazine and the two different ratio mixture.
Table 13 acequinocyl and the composite toxicity test analysis of results table to apple Tetranychus urticae of fluorine mite piperazine
| Reagent agent | Proportioning | LC 50(ug/mL) | Co-toxicity coefficient (CTC) |
| Acequinocyl | - | 1.61 | - |
| Fluorine mite piperazine | - | 0.52 | - |
| Go out Man Kun ︰ fluorine mite piperazine | 80∶1 | 0.89 | 176.54 |
| Go out Man Kun ︰ fluorine mite piperazine | 50∶1 | 0.82 | 188.93 |
| Go out Man Kun ︰ fluorine mite piperazine | 40∶1 | 0.79 | 194.32 |
| Go out Man Kun ︰ fluorine mite piperazine | 30∶1 | 0.68 | 222.42 |
| Go out Man Kun ︰ fluorine mite piperazine | 15∶1 | 0.62 | 230.82 |
| Go out Man Kun ︰ fluorine mite piperazine | 8∶1 | 0.54 | 243.94 |
| Go out Man Kun ︰ fluorine mite piperazine | 4∶1 | 0.45 | 255.56 |
| Go out Man Kun ︰ fluorine mite piperazine | 1∶1 | 0.33 | 243.94 |
| Go out Man Kun ︰ fluorine mite piperazine | 1∶5 | 0.26 | 232.21 |
| Go out Man Kun ︰ fluorine mite piperazine | 1∶10 | 0.25 | 228.52 |
| Go out Man Kun ︰ fluorine mite piperazine | 1∶20 | 0.27 | 205.28 |
| Go out Man Kun ︰ fluorine mite piperazine | 1∶40 | 0.28 | 194.83 |
| Go out Man Kun ︰ fluorine mite piperazine | 1∶50 | 0.30 | 181.26 |
| Go out Man Kun ︰ fluorine mite piperazine | 1∶80 | 0.31 | 174.55 |
As shown in Table 13, acequinocyl and fluorine mite piperazine to apple Tetranychus urticae proportioning when 1 ︰ 80 ~ 80 ︰ 1, co-toxicity coefficient is all greater than 120, both explanations mixture in 1 ︰ 80 ~ 80 ︰ 1 scope all shows synergistic effect, when the proportioning of acequinocyl and fluorine mite piperazine is at 1 ︰ 10 ~ 30 ︰ 1, synergistic effect is more obviously given prominence to, and co-toxicity coefficient is all greater than 220, wherein when acequinocyl and fluorine mite piperazine weight ratio are 4:1, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.Through applicant test find that acequinocyl and fluorine mite piperazine proportioning are 10:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:12,1:14,1:15,1:20,1:25,1:30 time to the two spotted spider mite in various crop, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, the beginning tetranychid, Shenmu-Yanan railway control have obvious synergistic effect, co-toxicity coefficient is all greater than 120.
Application Example six
For examination evil mite: apple tree two spotted spider mite
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective lethal concentration scope of preliminary experiment determination acequinocyl and the former medicine of fenisobromolate and the two different ratio mixture.
Table 14 acequinocyl and the composite toxicity test analysis of results table to apple tree two spotted spider mite of fenisobromolate
| Reagent agent | Proportioning | LC 50(ugmL) | Co-toxicity coefficient (CTC) |
| Acequinocyl | - | 1.49 | - |
| Fenisobromolate | - | 4.15 | - |
| Go out Man Kun ︰ fenisobromolate | 80∶1 | 0.88 | 170.67 |
| Go out Man Kun ︰ fenisobromolate | 50∶1 | 0.86 | 175.46 |
| Go out Man Kun ︰ fenisobromolate | 40∶1 | 0.80 | 189.21 |
| Go out Man Kun ︰ fenisobromolate | 20∶1 | 0.78 | 197.04 |
| Go out Man Kun ︰ fenisobromolate | 10∶1 | 0.72 | 219.75 |
| Go out Man Kun ︰ fenisobromolate | 5∶1 | 0.74 | 225.44 |
| Go out Man Kun ︰ fenisobromolate | 1∶1 | 0.89 | 246.38 |
| Go out Man Kun ︰ fenisobromolate | 1∶3 | 1.10 | 260.87 |
| Go out Man Kun ︰ fenisobromolate | 1∶8 | 1.39 | 249.16 |
| Go out Man Kun ︰ fenisobromolate | 1∶15 | 1.64 | 227.67 |
| Go out Man Kun ︰ fenisobromolate | 1∶30 | 1.81 | 216.82 |
| Go out Man Kun ︰ fenisobromolate | 1∶40 | 2.04 | 194.96 |
| Go out Man Kun ︰ fenisobromolate | 1∶50 | 2.13 | 188.26 |
| Go out Man Kun ︰ fenisobromolate | 1∶80 | 2.28 | 178.11 |
As shown in Table 14, acequinocyl and fenisobromolate to apple tree two spotted spider mite proportioning when 1 ︰ 80 ~ 80 ︰ 1, co-toxicity coefficient is all greater than 120, both explanations mixture in 1 ︰ 80 ~ 80 ︰ 1 scope all shows synergistic effect, when the proportioning of acequinocyl and fenisobromolate is at 1 ︰ 30 ~ 10 ︰ 1, synergistic effect is more obviously given prominence to, and co-toxicity coefficient is all greater than 215, wherein when acequinocyl and fenisobromolate weight ratio are 1:3, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.Through applicant test find that acequinocyl and fenisobromolate proportioning are 10:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:12,1:14,1:15,1:20,1:25,1:30 time to the two spotted spider mite in various crop, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, the beginning tetranychid, Shenmu-Yanan railway control have obvious synergistic effect, co-toxicity coefficient is all greater than 120.
Effect experiment part: test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, contrast medicament 15% acequinocyl suspending agent (autogamy), 20% clofentezine suspension agent (commercial), 25% azacyclotin wetting powder (commercial), 25% fenbutatin oxide suspending agent (commercial), 10% fluorine mite piperazine suspending agent (autogamy), 500 grams per liter fenisobromolate missible oil (commercial).
Application Example seven acequinocyl and active component B and the composite control mandarin tree two spotted spider mite test of pesticide effectiveness thereof, this test arrangement is in Hanzhong City suburb, Shaanxi Province, investigation mandarin tree two spotted spider mite damage index of spider mites before medicine, in the dispenser of mite evil initial stage of origination, 3 days, 15 days, 30 days investigation damage index of spider mites after dispenser also calculate preventive effect.Result of the test is as follows:
Table 15 acequinocyl and active component B and the composite control mandarin tree two spotted spider mite test of pesticide effectiveness thereof
As can be seen from Table 15, acequinocyl and active component B composite after can effectively prevent and treat mandarin tree two spotted spider mite, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example eight acequinocyl and active component B and the composite control apple tree tetranychus viennensis test of pesticide effectiveness thereof, this test arrangement is in Weinan City Dengcheng County, Shaanxi Province, investigation apple tree tetranychus viennensis damage index of spider mites before medicine, in the dispenser of mite evil initial stage of origination, 5 days, 20 days, 45 days investigation damage index of spider mites after dispenser also calculate preventive effect.Result of the test is as follows:
Table 16 acequinocyl and active component B and the composite control apple tree tetranychus viennensis test of pesticide effectiveness thereof
As can be seen from Table 16, acequinocyl and active component B composite after can effectively preventing and treating apple-tree tetranychus viennensis, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine acequinocyl and active component B and the composite control tomato goitre mite test of pesticide effectiveness thereof, this test arrangement is at Xian District, Shanxi Province suburban area, investigation tomato goitre mite damage index of spider mites before medicine, in the dispenser of mite evil initial stage of origination, 3 days, 10 days, 30 days investigation damage index of spider mites after dispenser also calculate preventive effect.Result of the test is as follows:
Table 17 acequinocyl and active component B and the composite control tomato goitre mite test of pesticide effectiveness thereof
As can be seen from Table 17, acequinocyl and active component B and composite control tomato goitre mite thereof, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten acequinocyl and active component B and the composite control mandarin tree Panonychus citri test of pesticide effectiveness thereof, this test arrangement is in Hanzhong City suburb, Shaanxi Province, investigation mandarin tree Panonychus citri damage index of spider mites before medicine, in the dispenser of mite evil initial stage of origination, 3 days, 15 days, 30 days investigation damage index of spider mites after dispenser also calculate preventive effect.Result of the test is as follows:
Table 18 acequinocyl and active component B and the composite control mandarin tree Panonychus citri test of pesticide effectiveness thereof
As can be seen from Table 18, acequinocyl and active component B composite after can effectively prevent and treat mandarin tree Panonychus citri, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 acequinocyl and active component B and the composite control cotton red spider test of pesticide effectiveness thereof, this test arrangement is in Weinan City Dali County, Shaanxi Province, investigation cotton red spider damage index of spider mites before medicine, in the dispenser of mite evil initial stage of origination, 3 days, 15 days, 30 days investigation damage index of spider mites after dispenser also calculate preventive effect.Result of the test is as follows:
Table 19 acequinocyl and active component B and the composite control cotton red spider test of pesticide effectiveness thereof
As can be seen from Table 19, acequinocyl and active component B composite after effectively can prevent and treat cotton red spider, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 12 acequinocyl and active component B and the composite control yellow tea mite test of pesticide effectiveness thereof, this test arrangement is in suburb, Ya'an, Sichuan Province, investigation yellow tea mite damage index of spider mites before medicine, in the dispenser of mite evil initial stage of origination, 3 days, 10 days, 20 days investigation damage index of spider mites after dispenser also calculate preventive effect.Result of the test is as follows:
Table 20 acequinocyl and active component B and the composite control yellow tea mite test of pesticide effectiveness thereof
As can be seen from Table 20, acequinocyl and active component B composite after effectively can prevent and treat yellow tea mite, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, acequinocyl and clofentezine, azacyclotin, fenbutatin oxide, fluorine mite piperazine, fenisobromolate composite rear to the two spotted spider mite in various crop, yellow spider, rust mite, Panonychus citri, goitre mite, tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, the beginning tetranychid, the common harmful mite such as Shenmu-Yanan railway preventive effect all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (7)
1. the miticide composition containing acequinocyl, effective active composition is active components A and active component B, it is characterized in that: active components A and active component B weight ratio are 1 ︰ 80 ~ 80 ︰ 1, and described active components A is acequinocyl, active component B is clofentezine, fluorine mite piperazine.
2. the miticide composition containing acequinocyl according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 50 ~ 50 ︰ 1.
3. the miticide composition containing acequinocyl according to claim 2, is characterized in that: the weight ratio of acequinocyl and clofentezine is 1 ︰ 30 ~ 30 ︰ 1; The weight ratio of acequinocyl and fluorine mite piperazine is 1 ︰ 10 ~ 30 ︰ 1.
4. the miticide composition containing acequinocyl according to any one of claim 1 to 3, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
5. the miticide composition containing acequinocyl according to claim 4 is for preventing and treating the purposes of evil mite on crops.
6. purposes according to claim 5, is characterized in that, described harmful mite is two spotted spider mite, yellow spider, rust mite, Panonychus citri, goitre mite.
7. purposes according to claim 5, is characterized in that, described harmful mite be tetranychus viennensis, yellow tea mite, Tetranychus cinnabarinus, Tetranychus urticae, the beginning tetranychid, Shenmu-Yanan railway.
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| CN101884331A (en) * | 2010-07-08 | 2010-11-17 | 东莞市瑞德丰生物科技有限公司 | Synergistic mite killing composition |
| CN101933518A (en) * | 2003-11-14 | 2011-01-05 | 拜尔农作物科学股份公司 | Active agent combinations with insecticidal and acaricidal properties |
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| CN101933518A (en) * | 2003-11-14 | 2011-01-05 | 拜尔农作物科学股份公司 | Active agent combinations with insecticidal and acaricidal properties |
| CN101884331A (en) * | 2010-07-08 | 2010-11-17 | 东莞市瑞德丰生物科技有限公司 | Synergistic mite killing composition |
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