CN103495061A - Traditional Chinese medicine composition for treating cholecystitis caused by stagnation of liver qi and phlegm and blood stasis - Google Patents
Traditional Chinese medicine composition for treating cholecystitis caused by stagnation of liver qi and phlegm and blood stasis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating cholecystitis caused by stagnation of liver qi and phlegm and blood stasis. The traditional Chinese medicine composition is prepared from Veronica ciliata Fisch, creticoside, radix bupleuri, buerger raspberry roots, pericarpium citri reticulatae, loofah sponge, caulis bambusae in taeniam, cynara scolymus, white dead nettle roots, loosestrife and madder. The traditional Chinese medicine composition can be clinically used for treating cholecystitis caused by stagnation of liver qi and phlegm and blood stasis.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of stagnation of liver-QI expectorant stasis of blood type cholecystitis.
Background technology
Chronic cholecystitis (chronic cholecystitis) refers to that gallbladder is lasting, inflammatory process that repeatedly show effect, clinical manifestation is upper right abdomen pain, or accompany right shoulder back radiating pain, can accompany the indigestion symptoms such as nauseating, vomiting, belch, acid regurgitation, anorexia be greasy.Abdomen examination can be without obvious sign, or abdomen light tenderness in upper right is only arranged, and Murphy levies or is positive.Ultrasound diagnosis shows thickening of capsule wall of gallbladder, owes smooth (even crude), or sees that strong echo group and sound shadow performance, process inventor's long-term practice draw, Chinese medicine treating the liver stagnated phlegm stasis of blood type cholecystitis has better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide the Chinese medicine composition of the treatment stagnation of liver-QI expectorant stasis of blood type cholecystitis that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Herba Veronicae Ciliatae, Jing Biancao, Radix Bupleuri, Radix rubi buergeri, Pericarpium Citri Reticulatae, Retinervus Luffae Fructus, Caulis Bambusae In Taenia, Cynara scolymus L (Cyhara cardunculus.), Radix Lamii barbati, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Radix Rubiae according to certain compatibility requirement, through being processed into.
Preparing Chinese medicine composition of the present invention is made by following raw material medicaments: Herba Veronicae Ciliatae 30-50 part, well limit grass 20-40 part, Radix Bupleuri 20-40 part, Radix rubi buergeri 20-40 part, Pericarpium Citri Reticulatae 10-30 part, Retinervus Luffae Fructus 10-30 part, Caulis Bambusae In Taenia 10-30 part, Cynara scolymus L (Cyhara cardunculus.) 10-30 part, Radix Lamii barbati 10-30 part, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 10-30 part, Radix Rubiae 8-12 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 40 parts of Herba Veronicae Ciliataes, 30 parts of well limit grass, 30 parts of Radix Bupleuri, 30 parts of Radix rubi buergeris, 20 parts of Pericarpium Citri Reticulataes, 20 parts of Retinervus Luffae Fructuss, 20 parts of Caulis Bambusae In Taenia, 20 parts of Cynara scolymus L (Cyhara cardunculus.), 20 parts of Radix Lamii barbatis, 20 parts of Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), 10 parts, Radix Rubiae.
The pharmacological action of Chinese medicine of the present invention is as follows:
Herba Veronicae Ciliatae: bitter, puckery, cold.Heat-clearing and toxic substances removing, expelling wind and removing dampness.Clinical in fever caused by exogenous pathogens, hepatitis, cholecystitis, rheumatic arthralgia, the diseases such as urticaria.
Well limit grass: hot, micro-hardship, cool.Return liver, large intestine channel, urinary bladder channel.Clearing away heat-damp and promoting diuresis, promoting blood circulation and detumescence.Clinical in dysentery, diarrhoea, edema, hepatitis, cholecystitis, sore throat, urinary system infection, carbuncle sore tumefacting virus, traumatic injury, the diseases such as fracture.
Radix Bupleuri: bitter, hot, be slightly cold, return liver, gallbladder meridian.Evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI.For stagnation of QI due to depression of the liver, pain in chest and hypochondrium.
Radix rubi buergeri: bitter, acid, cold.Return liver, kidney channel.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.Cure mainly jaundice due to damp-heat, puerperal fever, infantile hyperpyrexia, menoxenia, leukorrhagia, stomachache folic acid, swelling and pain of hemorrhoid, the diseases such as anus fistulae.
Pericarpium Citri Reticulatae: acrid, bitter, warm, return spleen, stomach, lung meridian.In regulating the flow of vital energy and adjusting, stopping nausea and vomiting by lowering the adverse flow of QI, drying dampness to eliminate phlegm.Full vexed for chest and diaphragm, abdominal distention, anorexia, vomiting etc.
Retinervus Luffae Fructus: sweet, flat.Return lung, stomach, Liver Channel.Dispelling wind and removing obstruction in the collateral, removing toxic substances is reduced phlegm.For rheumatic arthralgia, the thoracic obstruction, chest and hypochondrium etc.Caulis Bambusae In Taenia: sweet, be slightly cold, attach to the lung and stomach meridians.Removing heat-phlegm, relieve restlessness and prevent vomiting.For cough or the dysphoria and insomnia due to expectorant heat, gastropyretic vomiting etc.
Cynara scolymus L (Cyhara cardunculus.): sweet, flat.Depressed liver-energy dispersing and function of gallbladder promoting, rush down clearly damp and hot.Clinical in jaundice, two side of body distending pains, the diseases such as damp-heat dysentery.
Radix Lamii barbati: sweet in the mouth, property are put down.The liver heat removing dampness removing, promoting blood circulation and detumescence.Clinical in dizzy, hepatitis, cough hemoptysis, edema, leucorrhea, hemorrhoid, the diseases such as toxic swelling.
Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis): bitter, hot, flat.Return liver, spleen channel.Clearing away heat-damp and promoting diuresis, promoting blood circulation to remove blood stasis, removing toxicity for eliminating carbuncles.For edema, pyretic stranguria, jaundice, dysentery, rheumatism pyretic arthralgia, leukorrhagia, amenorrhea, traumatic injury, fracture, traumatic hemorrhage, acute mastitis, furuncle, the diseases such as venom.
Radix Rubiae: bitter, cold.GUIXIN, Liver Channel.Cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling.Clinical in the heat in blood spitting of blood, haematemesis, epistaxis, hematuria, have blood in stool, metrorrhagia, amenorrhea, postpartum stagnation stomachache, traumatic injury, rheumatic arthralgia, jaundice, carbuncle sore, hemorrhoid swell and wait disease.
Stagnation of liver-QI expectorant stasis of blood type cholecystitis belongs to the categories such as the traditional Chinese medical science " hypochondriac pain ", " feeling of fullness ".Primary disease state of an illness complexity, patient's condition is touching, and delay is difficult.Damp and hot bridle of a specified duration or hinder in feelings will stagnation of liver-QI make and to wet into expectorant and cause the stasis of blood.In the present invention, Herba Veronicae Ciliatae has the effect of heat-clearing and toxic substances removing, expelling wind and removing dampness, for monarch drug, well limit grass clearing away heat-damp and promoting diuresis, promoting blood circulation and detumescence, the Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI, be ministerial drug, Radix rubi buergeri heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, Pericarpium Citri Reticulatae, Retinervus Luffae Fructus, Caulis Bambusae In Taenia drying dampness to eliminate phlegm, Cynara scolymus L (Cyhara cardunculus.) depressed liver-energy dispersing and function of gallbladder promoting, Radix Lamii barbati liver heat removing dampness removing, promoting blood circulation and detumescence, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Radix Rubiae promoting blood circulation to remove blood stasis, clearing away heat-damp and promoting diuresis.Through clinical practice, find, stagnation of liver-QI expectorant stasis of blood type cholecystitis is had to unique curative effect, and all medicines are played the effect of heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, depressed liver-energy dispersing and function of gallbladder promoting altogether, reach the purpose for the treatment of stagnation of liver-QI expectorant stasis of blood type cholecystitis.
Chinese medicine composition of the present invention was in 2009 to 2011 clinical observation stagnation of liver-QI expectorant stasis of blood type cholecystitis 56 routine patients, and clinical report is as follows:
1, physical data
In 56 routine patients, age 18-65 year, the course of disease is many at 3 months to 8 years, 45 years old mean age.
2, diagnostic criteria
2.1 " traditional Chinese medical science disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
1. persistence upper right abdomen dull pain or sense of discomfort, or accompany right omoplate district pain; 2. the indigestion symptoms such as nauseating, belch, acid regurgitation, abdominal distention and scorching hot are arranged, the postemphasis of feed greasy food; 3. the course of disease is long, and the state of an illness has acute attack and alleviates characteristics alternately; 4. gallbladder area is carved with mild tenderness and kowtows pain; 5. in bile, mucus increases, and leukocyte is in heaps, positive bacterial culture; 6. the visible cholelithiasis of ultrasound diagnosis, thickening of capsule wall of gallbladder, gallbladder dwindles or is out of shape; 7. the visible cholelithiasis of cholecystography, gallbladder dwindles or is out of shape, and gallbladder contraction function is bad, or gallbladder develops thin.
Clinical symptoms: it is indefinite that hypochondriac pain is indistinctly walked to alter, and connects and take on also pain of back, and hypochondriac pain is fixing does not at nightfall move, the happiness sigh, and personality is suspicious, woman's menoxenia, the xerostomia hardship, purplish tongue gas, stringy and thready pulse, above symptom increases and decreases with feelings will quality.
2.2 exclusion standard:
1. the age is under-18s or over-65s person; 2. acute gangrenous cholecystitis, the suppurative cholecystitis of acute obstruction, perforation of gallbladder peritonitis person; 3. gestation or women breast-feeding their children, be associated with the serious primary disease such as cardiovascular, liver, kidney and hemopoietic system, psychotic.
3, Therapeutic Method
3.1 prescription: Herba Veronicae Ciliatae 40g, well limit grass 30g, Radix Bupleuri 30g, Radix rubi buergeri 30g, Pericarpium Citri Reticulatae 20g, Retinervus Luffae Fructus 20g, Caulis Bambusae In Taenia 20g, Cynara scolymus L (Cyhara cardunculus.) 20g, Radix Lamii barbati 20g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 20g, Radix Rubiae 10g.
3.2 method of preparation and use: said medicine technique is routinely made decoction, 1 dose of every day, every day 2 times, within 15 days, is 1 course for the treatment of.
4, therapeutic outcome:
4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":
Recovery from illness: the primary and secondary syndrome of this syndrome disappears, and ultrasound diagnosis gallbladder wall and contractile function recover normal ，Dan district pain and disappear, and diet, digestion recover normal.Drug withdrawal 3 months is unchanged, follows up a case by regular visits to half a year above without recurrence;
Take a turn for the better: this syndrome primary and secondary syndrome is improved and is accounted for more than halfly, and ultrasound diagnosis gallbladder wall and the contractile function ，Dan district tenderness that has clear improvement is clearly better, and diet, digestion are clearly better;
Invalid: through the treatment symptom, without alleviation, ultrasound diagnosis gallbladder wall and contractile function are without significant change, and every symptom is not improved.4.2 result: in 56 routine patients, 24 examples of fully recovering (42.8%), 28 examples that take a turn for the better (50%), invalid 4 examples (7.2%), total effective rate is 92.8%.
Model case
1, Wang, man, 45 years old.Suffer from cholecystitis 5 years.When medical, hypochondriac pain is indistinctly walked to alter indefinite, connects and also pain of shoulder back, and hypochondriac pain is fixing does not at nightfall move, xerostomia hardship, purplish tongue gas, stringy and thready pulse.Ultrasound diagnosis, cyst wall thickens, and volume increases, and gallbladder wall is rough and coarse.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, through the B ultrasonic check, and gallbladder clear-cut, smooth, the size and form normal, continue to take 2 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.
2, poplar, female, 36 years old, suffer from cholecystitis 4 years, immediate cause family lock thing, mind agitation, side of body rib walks to alter pain, bitterly, and fixing pain at nightfall, radiate delayed menstrual cycle, inappetence during pain to the shoulder back, appetite reduces, and body of the tongue has purple gas, and thin lingual fur is slightly yellow greasy, stringy and thready pulse, above symptom increases and decreases with feelings will quality.Take medicine of the present invention, 1 dose of every day, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, through the B ultrasonic check, and gallbladder clear-cut, smooth, size and form is normal, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
3, Chen, man, 51 years old.Because the upper right abdominal distention and pain once arrived certain hospital therapy, be diagnosed as acute cholecystitis, give the intravenous drip levofloxacin, remission.After this often upper right abdomen pain occurs while not relaxing because of the greasy or feelings will of taking food, and to the lower back radiation, the companion feels sick, vomiting, reaches 2 years.Because after feed Carnis Sus domestica, upper right abdomen dull pain occurring, abdominal distention, singultus, vomiting.The light tenderness of upper right abdomen, do not touch gallbladder, Murphy's sign (+).Ultrasound diagnosis: the gallbladder wall hair, thicken, visit and 3.0mm * 5.0mm stone-echo in capsule.Be diagnosed as stagnation of liver-QI expectorant stasis of blood type cholecystitis, cholelithiasis.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and continues to take 3 courses for the treatment of, and symptom and sign disappears, the B ultrasonic check: the gallbladder normal in size, wall is smooth, in capsule, does not visit and the stone-echo recovery from illness, after half a year, follows up a case by regular visits to without recurrence.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, a kind of Chinese medicine composition for the treatment of stagnation of liver-QI expectorant stasis of blood type cholecystitis is to be made by Herba Veronicae Ciliatae 30g, well limit grass 20g, Radix Bupleuri 20g, Radix rubi buergeri 20g, Pericarpium Citri Reticulatae 10g, Retinervus Luffae Fructus 10g, Caulis Bambusae In Taenia 10g, Cynara scolymus L (Cyhara cardunculus.) 10g, Radix Lamii barbati 10g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 10g, Radix Rubiae 8g.
Embodiment 2, a kind of Chinese medicine composition for the treatment of stagnation of liver-QI expectorant stasis of blood type cholecystitis is to be made by Herba Veronicae Ciliatae 40g, well limit grass 30g, Radix Bupleuri 30g, Radix rubi buergeri 30g, Pericarpium Citri Reticulatae 20g, Retinervus Luffae Fructus 20g, Caulis Bambusae In Taenia 20g, Cynara scolymus L (Cyhara cardunculus.) 20g, Radix Lamii barbati 20g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 20g, Radix Rubiae 10g.
Embodiment 3, a kind of Chinese medicine composition for the treatment of stagnation of liver-QI expectorant stasis of blood type cholecystitis is that Herba Veronicae Ciliatae 50g, well limit grass 40g, Radix Bupleuri 40g, Radix rubi buergeri 40g, Pericarpium Citri Reticulatae 30g, Retinervus Luffae Fructus 30g, Caulis Bambusae In Taenia 30g, Cynara scolymus L (Cyhara cardunculus.) 30g, Radix Lamii barbati 30g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 30g, Radix Rubiae 12g make.
Claims (2)
1. a Chinese medicine composition for the treatment of stagnation of liver-QI expectorant stasis of blood type cholecystitis is characterized in that it is to be made by following raw material medicaments:
Herba Veronicae Ciliatae 30-50 part, well limit grass 20-40 part, Radix Bupleuri 20-40 part, Radix rubi buergeri 20-40 part, Pericarpium Citri Reticulatae 10-30 part, Retinervus Luffae Fructus 10-30 part, Caulis Bambusae In Taenia 10-30 part, Cynara scolymus L (Cyhara cardunculus.) 10-30 part, Radix Lamii barbati 10-30 part, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 10-30 part, Radix Rubiae 8-12 part.
2. Chinese medicine composition according to claim 1 is characterized in that it is to be made by following raw material medicaments:
40 parts of Herba Veronicae Ciliataes, 30 parts of well limit grass, 30 parts of Radix Bupleuri, 30 parts of Radix rubi buergeris, 20 parts of Pericarpium Citri Reticulataes, 20 parts of Retinervus Luffae Fructuss, 20 parts of Caulis Bambusae In Taenia, 20 parts of Cynara scolymus L (Cyhara cardunculus.), 20 parts of Radix Lamii barbatis, 20 parts of Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), 10 parts, Radix Rubiae.
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Cited By (2)
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| CN104547721A (en) * | 2015-02-05 | 2015-04-29 | 王昌荣 | Traditional Chinese medicine for treating cholecystitis |
| CN105943830A (en) * | 2016-06-22 | 2016-09-21 | 岳宁宁 | Traditional Chinese medicine composition for treating cholecystitis |
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