CN103495039A

CN103495039A - Preparation method of spleen-strengthening and digestion-promoting traditional Chinese medicine capsules

Info

Publication number: CN103495039A
Application number: CN201310462674.9A
Authority: CN
Inventors: 不公告发明人
Original assignee: Wuhan Hong Xintong Science And Technology Ltd
Current assignee: Nantong Kai Kai Environmental Testing Technology Co., Ltd.
Priority date: 2013-09-30
Filing date: 2013-09-30
Publication date: 2014-01-08
Anticipated expiration: 2033-09-30
Also published as: CN103495039B

Abstract

The invention relates to a preparation method of spleen-strengthening and digestion-promoting traditional Chinese medicine capsules. The spleen-strengthening and digestion-promoting traditional Chinese medicine capsules are prepared from the following active pharmaceutical ingredients in parts by weight: 30 parts of Mongolian dandelion herb, 15 parts of jujube kernels, 6 parts of honey-fried liquorice root, 20 parts of dendrobium, 10 parts of Indian trum etflower seed and 10 parts of pinellia tuber. The preparation method comprises the following steps: taking the active pharmaceutical ingredients for later use; and mixing the active pharmaceutical ingredients, drying, crushing to form fine powder, screening by a 500-mesh screen and loading into capsules. The traditional Chinese medicine capsules have unexpected effects of strengthening spleen and promoting digestion.

Description

A kind of preparation method of strengthening the spleen to promote digestion Chinese medicinal capsule

Technical field

The present invention relates to technical field of Chinese medicines, be specially a kind of preparation method of strengthening the spleen to promote digestion Chinese medicinal capsule.

Background technology

Insufficiency of the spleen dysfunction of the spleen in transportation and transformation, and malnutrition can occur, water liquid loses in spreading and gives birth to the wet expectorant of making, or the disease such as lose blood.Its disease is at stomach, and dyspepsia relates to the internal organs such as liver spleen, and suitable determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, give invigorating the spleen and regulating the stomach, depressed liver-energy dispersing and QI regulating, the treatment of the methods such as dyspepsia and intestinal stasis relieving.But the western medicine side effect is larger, the Chinese patent medicine DeGrain that market is similar.

Summary of the invention

The objective of the invention is, in order to overcome above-mentioned the deficiencies in the prior art part, provides a kind of preparation method of strengthening the spleen to promote digestion Chinese medicinal capsule according to Chinese medical theory.

This method:

Get by weight 30 parts of crude drug Herba Taraxacis, 15 parts of Semen Ziziphi Spinosaes, 6 parts of Radix Glycyrrhizae Preparatas, 20 parts of Herba Dendrobiis, 10 parts of Semen Oroxylis and 10 parts of the Rhizoma Pinelliaes standby;

Second step: after the above-mentioned raw materials medicine is mixed, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate and get final product.

The invention provides method, its raw material is Herba Taraxaci, Radix Angelicae Sinensis, Radix Glycyrrhizae Preparata, Herba Dendrobii, Semen Oroxyli, Cortex Magnoliae Officinalis, Ramulus Cinnamomi, Herba Agrimoniae, Fructus Amomi, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Aucklandiae and the Rhizoma Pinelliae, can be used for the vomiting that treatment causes because of insufficiency of the spleen and dyspepsia, abdominal distention and become thin etc., the effect with certain strengthening the spleen to promote digestion that above-mentioned medical material has, the effect with certain building body had, after combination principle reasonable compatibility through the inventor according to monarch, discovery by its with this ratio compatibility after, make the medicine Synergistic of respectively distinguishing the flavor of, farthest brought into play effect, insufficiency of the spleen in treatment, dyspepsia, vomiting, abdominal distention and the aspect such as become thin have obtained the curative effect of showing, very few number is distinguished the flavor of, and but the efficacy of a drug is extensive.And the present invention is pure Chinese medicinal preparation, through 1 year, observe both without recurring also without obvious toxic and side effects.

The specific embodiment

A kind of preparation method of strengthening the spleen to promote digestion Chinese medicinal capsule, by following bulk drugs, made:

Herba Taraxaci 30g, Semen Ziziphi Spinosae 15g, Radix Glycyrrhizae Preparata 6g, Herba Dendrobii 20g, Semen Oroxyli 10g and Rhizoma Pinelliae 10g;

Second step: after the above-mentioned raw materials medicine is mixed, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate and get final product.Every capsule has above-mentioned raw materials medicine 0.4g.

The drug effect of each crude drug of distinguishing the flavor of is as follows:

1. Herba Taraxaci: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.

2. the Radix Rehmanniae: heat clearing away, promote the production of body fluid, moisturize, laxation, removing blood stasis with potent drugs, tissue regeneration promoting, pain relieving, regulating menstruation, the incised wound stasis of blood, removing heat from blood, hemostasis.

3. Radix Glycyrrhizae Preparata: spleen reinforcing stomach function regulating, Yiqi and vein recovery.

4. Herba Dendrobii: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.

5. the Rhizoma Pinelliae: drying dampness to eliminate phlegm, and middle stomach invigorating, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.

Instructions of taking: the people more than 18 years old three times on the one, each 1.Within 30 days, be a course for the treatment of, take continuously three courses for the treatment of.As taken continuously 1 week symptom without obviously changing or take medicine rear appearance diarrhoea and vomiting increase the weight of, drug withdrawal immediately, transference cure after drug withdrawal.

Clinical trial:

Choose 150 routine functional dyspepsias and with gastrointestinal upset as vomiting, abdominal distention and the Patients of Spleen Deficiency of becoming thin, in age 18-50 year, the course of disease is more than 3 months, in 2 months, do not carry out any treatment.Above-mentioned 150 routine patients are divided into to two groups for the treatment of group and matched groups, treatment group 100 examples, the capsule made with this enforcement is treated, and three times on the oral one, each 1 30 days is a course for the treatment of, takes continuously three courses for the treatment of.Matched group 50 examples, take the domperidone tablet treatment: oral, 10～20mg or suspension 10ml, every day 3～4 times, take 15～30 minutes ante cibum, within 15 days, is a course for the treatment of, takes continuously three courses for the treatment of.Then carry out clinical observation.

Period in a medicine treatment group self clinical observation on the therapeutic effect analysis result is as follows:

The curative effect project	The treatment group number of cases	Improvement rate (%)
			The vomiting number of times reduces	82	82%
Abdominal distention is alleviated	83	83%
			Body weight increases	85	85%
Appetite increases	90	90%
			Total improvement rate (%)	?	85%

The clinical observation on the therapeutic effect analysis result of period in a medicine treatment group and matched group is as follows:

Efficacy assessment standard is as follows:

1, produce effects: vomiting is obviously controlled, and abdominal distention is obviously alleviated, and body weight increases, and appetite increases, the transference cure of all the other gastrointestinal upsets.

2, take a turn for the better: the vomiting number of times reduces or the intermittent time extends, and abdominal distention is alleviated to some extent, and body weight stops alleviating, and appetite makes moderate progress, and the symptom partial symptoms of all the other gastrointestinal upsets disappears.

3, invalid: symptom is without improving or increasing the weight of.

The comparison sheet of the clinical medicine side effect incidence rate of period in a medicine treatment group and matched group

Stomachache and Refuse to take medicine are clinical modal side effect as can be seen from the above table, but can progressively disappear after drug withdrawal.But tremble and the incidence rate of the side effect of having blood in stool, take the matched group of domperidone tablet apparently higher than the treatment group of taking capsule of the present invention, so the present invention does not have obvious toxic and side effects substantially.

Claims

1. the preparation method of a strengthening the spleen to promote digestion Chinese medicinal capsule, is characterized in that comprising the steps:

The first step: get by weight 30 parts of crude drug Herba Taraxacis, 15 parts of Semen Ziziphi Spinosaes, 6 parts of Radix Glycyrrhizae Preparatas, 20 parts of Herba Dendrobiis, 10 parts of Semen Oroxylis and 10 parts of the Rhizoma Pinelliaes standby;