CN103495006A - Traditional Chinese medicine composition for treating toothache - Google Patents

Abstract

A traditional Chinese medicine composition for treating toothache relates to the technical field of Chinese herbal medicines, and is a medicament prepared from the following bulk drugs in parts by weight: 2-4 parts of asarum herb, 8-10 parts of rhizomaligustici, 8-10 parts of gentianamacrophylla, 8-10 parts of floseriocauli, 8-10 parts of allium tuberosumrottler roots and 8-10 parts of cimicifugafoetida. The traditional Chinese medicine composition is accord with traditional Chinese medicine syndrome differentiation theory on traditional Chinese medicinal material selection and compatibility; the traditional Chinese medicine composition is substantial in treatment effect and none in toxic and side effects; and the traditional Chinese medicine composition mainly aims at relieving pain, moving qi, dispelling wind dampness, relaxing sinews and collaterals and clearing deficiency heat, and helps to reach the purpose of complementing each other in traditional Chinese medicine compatibility.

Description

A kind of Chinese medicine composition of having a toothache that is used for the treatment of

Technical field

The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of Chinese medicine composition of having a toothache that is used for the treatment of.

Background technology

Having a toothache and have a toothache, is one of modal symptom of department of stomatology odontopathy, and it shows as red swelling of gingiva, meets caloric stimulation pain, buccal swelling etc.A lot of odontopathy can cause toothache, common are dental caries, acute pulpitis, chronic pulpitis, periodontitis, gingivitis etc.As the saying goes that " have a toothache and be not disease, pain is got up, and what an awful nuisance " illustrated the misery of having a toothache, have a toothache and have a strong impact on people's orthobiosis, prolonged and repeated having a toothache also can cause other odontopathy, and the harm people's is healthy.

Treatment is now had a toothache and is mainly treated by medicine, and easing pain and diminishing inflammation medicine for oral administration or externally used antimicrobial anti-inflammation drugs, but actual effect is undesirable, easily recurrence.

Summary of the invention

It is a kind of effective that technical problem to be solved by this invention is to provide, the safe and reliable Chinese medicine composition of having a toothache that is used for the treatment of.

Technical problem to be solved by this invention realizes by the following technical solutions:

A kind of Chinese medicine composition of having a toothache that is used for the treatment of, the medicament of being made by the crude drug of following weight portion,

Herba Asari 2-4 part, Rhizoma Ligustici 8-10 part, Radix Gentianae Macrophyllae 8-10 part, Flos Eriocauli 8-10 part, Radix et Bulbus Allii tuberosi 8-10 part, Rhizoma Cimicifugae 8-10 part.

Preferred weight part of each crude drug is:

3 parts of Herba Asaris, 9 parts of Rhizoma Ligusticis, 9 parts of Radix Gentianae Macrophyllae, 9 parts of Flos Eriocaulis, 9 parts of Radix et Bulbus Allii tuberosi, 9 parts of Rhizoma Cimicifugaes.

The present invention's crude drug used can be bought and obtain from the common Chinese shop, and its specification meets national Chinese crude drug standard and gets final product.

Another object of the present invention is to provide a kind of method for preparing the present composition, comprises the steps,

1) take by the described parts by weight of prescription the crude drug of respectively distinguishing the flavor of;

2) the above-mentioned material medicine of respectively distinguishing the flavor of is mixed be placed in marmite and add water and do not have powder, after soaking 30 minutes, use slow fire boiling, after boiling, renew and decoct 30 minutes, decoct altogether three times, merge three decocting liquids and filter, obtain decoction.

1, pharmacology analysis:

Herba Asari: acrid in the mouth; Warm in nature; Mild toxicity.Cold expelling dispels the wind; Pain relieving; Warming the lung to resolve fluid-retention; Sensible.Exterior syndrome due to wind-cold; Headache, toothache etc.

Rhizoma Ligustici: suffering, temperature.Return urinary bladder channel.Dispel the wind, cold expelling, dehumidifying, pain relieving.Calmness, analgesia, analgesic and antiinflammatory action.

Radix Gentianae Macrophyllae: hot, bitter, be slightly cold.Return stomach warp, Liver Channel, gallbladder meridian.Eradicates rheumatism, relaxing muscles and tendons network, clearind deficient heat.

Flos Eriocauli: Xin Gan is cool.Enter liver, stomach warp.Wind and heat eliminating, improving acuity of vision and removing nebula.Control corneal nebula, night blindness, headache, toothache, sore throat, epistaxis.

Radix et Bulbus Allii tuberosi: suffering, temperature.Root and bulb for liliaceous plant fragrant-flowered garlic.Warming middle-JIAO, circulation of qi promoting, dissipating blood stasis.There is antibacterial action.

Rhizoma Cimicifugae: hot, micro-sweet, be slightly cold.Return lung, spleen, stomach, large intestine channel.Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption.

2, usage and consumption:

The dosage of medicine of the present invention depends on concrete dosage form, and the factor such as age of patient, body weight, health status.Instruction: decoction: a pair once, is taken after supper, within 3 days, is a course for the treatment of.

3, the present composition has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and treatment disease, and the use link that this medicine is dropped into to the treatment disease provides science and objective foundation.Its test method and result of the test are as follows respectively:

1) decoction prepared by the present invention carries out animal acute toxicity test:

Medicine: the present invention's crude drug used is bought and is obtained from the common Chinese shop, and its specification meets national Chinese crude drug standard.

Experimental animal: white mice, body weight is in the 50g left and right, and male and female are selected at random, by market, are bought.

Method and result: get 10 of white mice, hungry about 20 hours, fill with for 5 times and feed 40ml by every every natural gift, feed one week continuously, to observe 10 days, mice is movable normal, and non-toxic reaction, without dead.Show that oral liquid is without acute toxicity, clinical medicine dose safety.

2) decoction prepared by the present invention carries out long-term toxicity test for animals:

Experimental animal: rat, body weight is at 120-130g, and male and female are selected at random, by market, are bought.

Method and result: get 20 of rat, be divided into 2 groups, every group 10, wherein the 1st group as the administration group, by filling with for 2 times every every day, feed, each 5-10ml does not wait, the 2nd group of normal feeding as a control group, once a day, continuous irrigation is fed 90 days, survey body weight, 24 hours sacrificed by decapitation after last administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the variation of tissues observed form, observe the effect of dosage, observe diet, movable variation, experimental results show that administration group and matched group are relatively without significant change, equal non-toxic reaction, a kind of safe drugs.

4, diagnostic criteria

1) clinical diagnosis: there is the clinical symptoms of having a toothache.

2) in order to verify clinical efficacy, this prescription is tried out in First People's Hospital, Jieshou City, Anhui Province respectively, chooses at random wherein 50 routine patients.

3) Therapeutic Method: according to drug ratios of the present invention, take raw material (dosage), according to the method for usually boiling medicine, obtain medicinal liquid, take after supper, taking 3 days is a course for the treatment of.The shortest 1 course for the treatment of, the longest 8 courses for the treatment of.

4) efficacy determination:

Recovery from illness: the clinical symptoms of having a toothache is improved fully, the functional rehabilitation such as chews normal; Produce effects: the clinical symptoms of having a toothache is significantly improved, and can normally chew, have a meal; Effectively: clinical its symptom of having a toothache changes, and can have a meal, and occasionally discomfort is arranged, and can accept; Invalid: as to treat rear symptom, sign and compare before treatment without any change; Concrete therapeutic outcome is referring to table 1.

Table 1

Number of cases	Recovery from illness	Produce effects	Effectively	Invalid	Effective percentage (%)
						50	17	24	6	3	94

5, points for attention:

1. diet should be light, gives up alcohol and pungent, raw and cold, greasy food.

2. child, women breast-feeding their children, elderly and infirm should take under the doctor instructs.

3. driver, work high above the ground person are cautious use of.

4. strictly by usage and dosage, take.

5. to this medicine and ethanol allergy sufferers forbidding, allergic constitution the person be cautious use of.

6. when this property of drug changes, ban use of.

7. this medicine please be placed on to the place that the child can not contact.

8. as use other medicines, using please Ref Dr or pharmacist before this medicine.

The invention has the beneficial effects as follows: the present invention meets the Chinese medical discrimination theory on Chinese crude drug selection and compatibility, therapeutic effect is remarkable, and have no side effect, mainly take pain relieving, circulation of qi promoting, Eradicates rheumatism, relaxing muscles and tendons network, clearind deficient heat as main, reached complementary purpose in drug matching.

The specific embodiment

For technological means, creation characteristic that the present invention is realized, reach purpose and effect is easy to understand, below in conjunction with specific embodiment, further set forth the present invention.

Embodiment 1

Take each crude drug by following parts by weight: Herba Asari 3g, Rhizoma Ligustici 9g, Radix Gentianae Macrophyllae 9g, Flos Eriocauli 9g, Radix et Bulbus Allii tuberosi 9g, Rhizoma Cimicifugae 9g.The above-mentioned material medicine of respectively distinguishing the flavor of is mixed to be placed in marmite add water and do not have powder, after soaking 30 minutes, use slow fire boiling, after boiling, renew and decoct 30 minutes, decoct altogether three times, merge three decocting liquids and filter, obtain decoction, one pair once, is taken after supper, 3 days courses for the treatment of.

Embodiment 2

Take each crude drug by following parts by weight: Herba Asari 4g, Rhizoma Ligustici 10g, Radix Gentianae Macrophyllae 10g, Flos Eriocauli 10g, Radix et Bulbus Allii tuberosi 10g, Rhizoma Cimicifugae 10g.The above-mentioned material medicine of respectively distinguishing the flavor of is mixed to be placed in marmite add water and do not have powder, after soaking 30 minutes, use slow fire boiling, after boiling, renew and decoct 30 minutes, decoct altogether three times, merge three decocting liquids and filter, obtain decoction, one pair once, is taken after supper, 3 days courses for the treatment of.

Embodiment 3

Take each crude drug by following parts by weight: Herba Asari 2g, Rhizoma Ligustici 8g, Radix Gentianae Macrophyllae 8g, Flos Eriocauli 8g, Radix et Bulbus Allii tuberosi 8g, Rhizoma Cimicifugae 8g.The above-mentioned material medicine of respectively distinguishing the flavor of is mixed to be placed in marmite add water and do not have powder, after soaking 30 minutes, use slow fire boiling, after boiling, renew and decoct 30 minutes, decoct altogether three times, merge three decocting liquids and filter, obtain decoction, one pair once, is taken after supper, 3 days courses for the treatment of.

Model case:

Case 1

Lee, man, 24 years old, people from Shou County, Liuan City, Anhui Province.Summer in 2011 causes having a toothache because getting angry, not good to the examination in hospital therapeutic effect.After take decoction of the present invention, after 2 days, pain disappears, after take again one week, recovery from illness, follow up a case by regular visits to 1 year, is recurrence.

Case 2

Wool grass, man, 54 years old, peasant, Jieshou City, Anhui Province grain husk South Street Taoist.Have a toothache one week, treatment has no resolution, after take the present invention's decoction of writing out a prescription, within 2 days, pain symptom disappears, recovery from illness in a week, follow up a case by regular visits to, and recurs.

Case 3

Chen, man, 11 years old, student, Niu Zhuan people from village, Jin Zhai administrative village, Jin Zhai township, Jieshou City, Anhui Province.The aching and limp discomfort of sensation tooth during because of feed, the household is with him medical to health clinics in towns and townships, and he is dental caries for diagnosis, to him, with furacillin solution, cleans and suffers from tooth, and his amoxicillin of open is oral afterwards.Treat and do not take effect in 3 days.After take decoction of the present invention, after 1 course for the treatment of, pain disappears, after take continuously again 4 courses for the treatment of, transference cure, recovery from illness.Following up a case by regular visits to 1 year, is recurrence.

Case 4

Understand so-and-so, the man, 36 years old, the company personnel, lived Jin Zhai township, Jieshou City, Anhui Province.Once suffer from and having a toothache many days, treat undesirable through doctor trained in Western medicine, routine of western medicine.Take decoction prepared by the present invention, after 1 course for the treatment of, pain disappears, after take continuously again 4 courses for the treatment of, follow up a case by regular visits to 1 year, be recurrence.

Case 5

Shut out so-and-so, female, 52 years old, peasant, grate people from town, Dingyuan County, Anhui Province.Once had a toothache repeatedly and took western medicine and do not heal.Take decoction prepared by the present invention, after 2 courses for the treatment of, pain disappears, after take continuously again 4 courses for the treatment of, follow up a case by regular visits to 1 year, be recurrence.

Above demonstration and described ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; that in above-described embodiment and description, describes just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.The claimed scope of the present invention is defined by appending claims and equivalent thereof.

Claims (6)

1. one kind is used for the treatment of the Chinese medicine composition of having a toothache, and it is characterized in that: the medicament of being made by the crude drug of following weight portion,

Herba Asari 2-4 part, Rhizoma Ligustici 8-10 part, Radix Gentianae Macrophyllae 8-10 part, Flos Eriocauli 8-10 part, Radix et Bulbus Allii tuberosi 8-10 part, Rhizoma Cimicifugae 8-10 part.

2. a kind of Chinese medicine composition of having a toothache that is used for the treatment of according to claim 1 is characterized in that: the medicament of being made by the crude drug of following weight portion,

3 parts of Herba Asaris, 9 parts of Rhizoma Ligusticis, 9 parts of Radix Gentianae Macrophyllae, 9 parts of Flos Eriocaulis, 9 parts of Radix et Bulbus Allii tuberosi, 9 parts of Rhizoma Cimicifugaes.

3. a kind of Chinese medicine composition of having a toothache that is used for the treatment of according to claim 1, it is characterized in that: described preparation is oral formulations.

4. a kind of Chinese medicine composition of having a toothache that is used for the treatment of according to claim 3, it is characterized in that: described oral formulations is capsule or pill.

5. a method for preparing claim 1 or the described Chinese medicine composition of 2 any one is characterized in that: comprises the following steps,

1) take by the described parts by weight of prescription the crude drug of respectively distinguishing the flavor of;

2) the above-mentioned material medicine of respectively distinguishing the flavor of is mixed be placed in marmite and add water and do not have powder, after soaking 30 minutes, use slow fire boiling, after boiling, renew and decoct 30 minutes, decoct altogether three times, merge three decocting liquids and filter, obtain decoction.

6. according to the purposes of the described Chinese medicine composition of claim 1 or 2 in medicine is had a toothache in treatment.