CN102895505B - Medicine for treating dental caries toothache - Google Patents
Medicine for treating dental caries toothache Download PDFInfo
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- CN102895505B CN102895505B CN201210368738.4A CN201210368738A CN102895505B CN 102895505 B CN102895505 B CN 102895505B CN 201210368738 A CN201210368738 A CN 201210368738A CN 102895505 B CN102895505 B CN 102895505B
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Abstract
The invention relates to the medical field, in particular to a medicine for treating dental caries toothache and solves the problems that prior medicines for preventing and treating dental caries almost are western medicines, the efficacy is not obvious, toxic and side effects are strong, and the dental caries is prone to relapse and the like. The traditional Chinese medicines for preparing effective components include, by weight, 8%-12 % of common cnidium fruits, 8%-12% of dwarf lilyturf tuber, 6%-10% of common anemarrhena rhizome, 6%-10% of cape jasmine fruits, 10%-20% of fossil fragments, 30%-40% of plasters, 1%-3% of asarum and 8%-12% of dried tangerine peels. According to the medicine for treating the dental caries toothache, the Chinese traditional medicines are supplementary to each other, efficacies of clearing heat, detoxifying, reducing swelling and reliving pains are achieved, the medicine is mainly used in treating dental caries toothache, periodontitis, gingivitis and the like and has good antibacterial, anti-inflammation and reliving toothache effects, and the medicine is a pure traditional Chinese medicine preparations, free of toxic and side effects, simultaneously convenient to carry and take and suitable for numerous patients to take.
Description
Technical field
The present invention relates to field of medicaments, be specially a kind of medicine for the treatment of toothache due to dental caries.
Background technology
Dental caries (decayed tooth) is a kind of extremely common oral disease, dental caries is a kind of destructive disease occurring on hard tooth tissue, that the softening and organic dissolving of sclerous tissues occurs gradually tooth under the impact of human body internal and external environment factor, make that dental tissue suffers to destroy, damaged disease, dental caries is not only destroyed organ of mastication, hinder digestive function, but also understand concurrent pulpitis, periodontitis, gingivitis etc., and then affect whole body health, be embodied in: sickness rate is high, be difficult for repairing, hazardness is large, and serious root dental caries will cause loss of tooth.Concerning child, bad root of the tooth is not only an impediment to food and chews, being an impediment to nutrition digestion absorbs, also can make the growth promoter of jawbone be affected simultaneously, for old people, serious dental caries can cause most of absence of tooth or whole disappearances, has increased the weight of old people's gastrointestinal burden, is unfavorable for that old people's is healthy.
Existing Therapeutic Method be adopt that medicinal agent is sucked method, the method for gargling, Borneolum Syntheticum are reduced internal heat method; Anesthetis drop method, anesthetis absorbent liquor ball osmosis for Western medicine, antibiotic intravenous drip method for serious case, carry out the means such as antiinflammatory, periodontal method of cleaning, but effect is very unobvious, and is mostly Western medicine, and toxic and side effects is large, easily recurrence.In recent years, Chinese medicine is applied to concern and the attention that prevention and the treatment pharmacology of dental caries and the research of mechanism start to be subject to Chinese scholars, therefore develops a kind of determined curative effect, the convenient and practical medicine of preventing and treating dental caries and alleviating toothache is becoming inevitable.
Summary of the invention
The present invention is mostly the problems such as Western medicine, DeGrain, large, the easy recurrence of toxic and side effects in order to solve the existing medicine of preventing and treating dental caries, and a kind of medicine for the treatment of toothache due to dental caries is provided.
The present invention adopts following technical scheme to realize: a kind of medicine for the treatment of toothache due to dental caries, the raw material of Chinese medicine of making effective ingredient consists of by following weight ratio: Fructus Cnidii 8 ~ 12%, Radix Ophiopogonis 8 ~ 12%, the Rhizoma Anemarrhenae 6 ~ 10%, Fructus Gardeniae 6 ~ 10 %, Os Draconis 10 ~ 20%, Gypsum Fibrosum 30 ~ 40%, Herba Asari 1 ~ 3%, Pericarpium Citri Reticulatae 8～12%.
The optimum formula of medicine of the present invention is, Fructus Cnidii 11%, Radix Ophiopogonis 11%, the Rhizoma Anemarrhenae 8%, Fructus Gardeniae 8%, Os Draconis 15%, Gypsum Fibrosum 34%, Herba Asari 2%, Pericarpium Citri Reticulatae 11%.
After above-mentioned raw materials is mixed clearly respectively, cleans, is dried, is sterilized, can make according to traditional pharmaceutical technology the oral medicine of various dosage forms, such as dosage forms such as tablet, dispersant, pill, soft capsule, granule, decoctions, this is that those of ordinary skill in the art is easy to realize.
In said medicine, Fructus Cnidii is pungent, bitter, temperature, removing toxic substances parasite killing dampness is dispeled the wind, and modern medicine proves that it has resisting pathogenic microbes effect and local anesthesia effect, Radix Ophiopogonis, sweet, micro-hardship, is slightly cold, YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire, for dryness of the lung dry cough, Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, pharyngeal diphtheria, modern medicine proves that it has sedation simultaneously; The Rhizoma Anemarrhenae: bitter, sweet, cold, clearing away heat-fire, promotes the production of body fluid and moisturize, and has the effect of pathogenic fire purging relieving restlessness, and modern medicine proves that it has resisting pathogenic microbes effect and refrigeration function simultaneously.Fructus Gardeniae: bitter, cold, nontoxic, pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, have the effect of clearing heat and relieving fidgetness.Os Draconis: sweet puckery, flat, have tranquillizing the mind by relieving convulsion, tonifying YIN YANG hyperactivity suppressing, restrain astringent or styptic treatment for spontaneous sweating, the effect of promoting tissue regeneration and ulcer healing.Gypsum Fibrosum: pungent, sweet, Great Cold, expelling pathogenic factors from muscles for clearing heat, relieving restlessness is quenched the thirst, heat-clearing and toxic substances removing, pathogenic fire purging, cures mainly hot lesion, and heat is not moved back, vexed coma, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, stomach-fire headache, toothache, hyperactivity of toxic heat, sends out speckle dermexanthesis, aphtha of the mouth and tongue; Herba Asari: acrid in the mouth, warm in nature, mild toxicity, the cold expelling that induces sweat, wind-expelling pain-stopping, warming the lung to resolve fluid-retention, sensible, cure mainly that cold expelling dispels the wind, pain relieving, warming the lung to resolve fluid-retention, sensible, for anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis; Pericarpium Citri Reticulatae: warm in nature, acrid in the mouth, bitter in the mouth, having and regulating the flow of vital energy in tune, the effect of removing dampness by means of aromatics, modern medicine proves that it has antiinflammatory, antiulcer action simultaneously.
Pharmaceutical formulation of the present invention and proportioning are that applicant obtains according to theory of Chinese medical science and clinical experience for many years, wherein Fructus Cnidii, Radix Ophiopogonis, Os Draconis have calmness, anesthetic action, alleviate toothache, the Rhizoma Anemarrhenae, Fructus Gardeniae, Gypsum Fibrosum have that dampness removing is moisturized, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body effect, Herba Asari, Pericarpium Citri Reticulatae dredge the meridian passage, eliminating stasis to stop pain, Pericarpium Citri Reticulatae has dampness antiinflammatory, antiulcer action simultaneously.
Compared with prior art, medicine of the present invention complements each other, the effect that is altogether heat-clearing and toxic substances removing, reducing swelling and alleviating pain, be mainly used in the treatment of the diseases such as caries pain and periodontitis, gingivitis, having antibacterial, antiinflammatory effect, alleviate the effect of toothache, is pure Chinese medicinal preparation, has no side effect, carry taking convenience simultaneously, be applicable to numerous patients and take.
In order to show the therapeutic effect of medicine of the present invention, the present invention has carried out following clinical experiment:
Clinical data: in the routine patient of clinical observation so far 50 in 2010, comprising eurodonticus's 30 examples, patients with periodontitis 12 examples, gingivitis 8 examples.
Therapeutic Method: pharmaceutical formulation of the present invention is made to capsule according to traditional pharmaceutical technology, and each two, one day three times 7 days is a course for the treatment of.
Curative effect determinate standard:
Clinical recovery a: course for the treatment of of medication, symptom alleviates, in 5 days, clinical symptoms and sign disappear;
Effective: medication alleviates with interior symptom two courses for the treatment of, clinical and most of sign disappearance in 5 days;
Effective: medication alleviates with interior symptom two courses for the treatment of, clinical and part sign disappearance in 5 days;
Invalid: medication two courses for the treatment of, sign was not improved with interior symptom without obviously alleviating.
Therapeutic effect: clinical cure 37 examples (74%), effective 6 examples (12%), effective 4 examples (4%), invalid 3 examples (6%), total effective rate is 94%.
Model case:
1, Li Xiaojing, female, 7 years old, on March 5th, 2010, had a toothache a few days in upper left, checked spottiness, and face is not obvious swollen, and 38.2 ℃ of body temperature, are diagnosed as dental caries tooth, and clothes medicine-feeding 3 days, alleviates on the 1st day, then takes 2 days pain and disappear completely, not recurrence in more than 10 year
2, Qin Xiaoyi, man, 11 years old, have a toothache a few days in upper left; there is the hole that 0.5mm is large on the tooth top that checks pain, takes somedon, indometacin before, and detoxicating tablet of cow-bezoar etc. are invalid; JIUYUE in 2011 takes above-mentioned medicine on the 10th and alleviates for two days, then takes 3 days pain and disappear completely, not recurrence in 5 years.
3, Wang Zhili, man, 36 years old, the upper right pain of having a toothache, can not have a meal, 37.5 ℃ of body temperature, pain tooth tip have Semen Glycines large hole, toothache place red swelling of gingiva, defeated cephalosporin alleviates when pain before, pain is contained and is taken ibuprofen and relieve the pain, and produces effect, easily recurrence.Take this medicine 3 days on May 10th, 2011, toothache symptom alleviates, and continues to take 4 days, and symptom disappears completely.Not recurrence in 8 years
4, Liu Xiaojuan, female, 40 years old, the upper left dental caries teeth pain several years, because of dental caries, have a toothache and pull out 1, find another 1 pain of having a toothache, by eating somedon, relieve the pain, take this medicine 2 remotest places on April 16th, 2012, toothache symptom alleviates, and continues to take 3 days, and symptom disappears completely.Not recurrence in 4 years
5, Li Yan, within 12 years old, have a toothache 3 days in upper left, 38.3 ° of C of body temperature, tentative diagnosis is toothache due to dental caries, on March 5th, 2010 is taken above-mentioned medicine 1 day, pain relief.Continue to take 2 days, pain disappears completely.So far not recurrence.
The specific embodiment
Embodiment 1:
Treat a medicine for toothache due to dental caries, the raw material of Chinese medicine of making effective ingredient consists of by following weight ratio: Fructus Cnidii 8%, Radix Ophiopogonis 8%, the Rhizoma Anemarrhenae 10%, Fructus Gardeniae 10 %, Os Draconis 10%, Gypsum Fibrosum 40%, Herba Asari 3%, Pericarpium Citri Reticulatae 11%.Choose above-mentioned high-quality Chinese herbal medicine, respectively assorted clearly, clean, after dry, sterilization, pulverize and sieve operation, be crushed to 200 ~ 400 order powder, obtain above-mentioned various Chinese herbal medicine powder; Chinese herbal medicine powder is mixed in proportion to homogenizing, then after disinfection by ultraviolet light, incapsulates and obtain medicine of the present invention.
Embodiment 2:
Treat a medicine for toothache due to dental caries, the raw material of Chinese medicine of making effective ingredient consists of by following weight ratio: Fructus Cnidii 12%, Radix Ophiopogonis 12%, the Rhizoma Anemarrhenae 6%, Fructus Gardeniae 6 %, Os Draconis 20%, Gypsum Fibrosum 30%, Herba Asari 2%, Pericarpium Citri Reticulatae 12%.The conventional method of processing according to Chinese medicine is by the agent of said medicine granulation.
Embodiment 3: a kind of medicine for the treatment of toothache due to dental caries, the raw material of Chinese medicine of making effective ingredient consists of by following weight ratio: Fructus Cnidii 11%, Radix Ophiopogonis 11%, the Rhizoma Anemarrhenae 8%, Fructus Gardeniae 8%, Os Draconis 15%, Gypsum Fibrosum 34%, Herba Asari 2%, Pericarpium Citri Reticulatae 11%.Conventional method according to Chinese medicine processing is made tablet by said medicine.
Embodiment 4:
Treat a medicine for toothache due to dental caries, the raw material of Chinese medicine of making effective ingredient consists of by following weight ratio: Fructus Cnidii 10%, Radix Ophiopogonis 10%, the Rhizoma Anemarrhenae 7%, Fructus Gardeniae 10 %, Os Draconis 18%, Gypsum Fibrosum 36%, Herba Asari 1%, Pericarpium Citri Reticulatae 8%.Conventional method according to Chinese medicine processing is made dispersant by said medicine.
Embodiment 5:
Treat a medicine for toothache due to dental caries, the raw material of Chinese medicine of making effective ingredient consists of by following weight ratio: Fructus Cnidii 9%, Radix Ophiopogonis 12%, the Rhizoma Anemarrhenae 8%, Fructus Gardeniae 9%, Os Draconis 18%, Gypsum Fibrosum 32%, Herba Asari 2%, Pericarpium Citri Reticulatae 10%.Preparation method is as embodiment 1.
Claims (2)
1. a medicine for the treatment of toothache due to dental caries, it is characterized in that the raw material of Chinese medicine of making effective ingredient consists of by following weight ratio: Fructus Cnidii 8 ~ 12%, Radix Ophiopogonis 8 ~ 12%, the Rhizoma Anemarrhenae 6 ~ 10%, Fructus Gardeniae 6 ~ 10 %, Os Draconis 10 ~ 20%, Gypsum Fibrosum 30 ~ 40%, Herba Asari 1 ~ 3%, Pericarpium Citri Reticulatae 8～12%.
2. a kind of medicine for the treatment of toothache due to dental caries according to claim 1, is characterized in that the raw material of Chinese medicine of making effective ingredient consists of by following weight ratio: Fructus Cnidii 11%, Radix Ophiopogonis 11%, the Rhizoma Anemarrhenae 8%, Fructus Gardeniae 8%, Os Draconis 15%, Gypsum Fibrosum 34%, Herba Asari 2%, Pericarpium Citri Reticulatae 11%.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210368738.4A CN102895505B (en) | 2012-09-28 | 2012-09-28 | Medicine for treating dental caries toothache |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210368738.4A CN102895505B (en) | 2012-09-28 | 2012-09-28 | Medicine for treating dental caries toothache |
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| CN102895505A CN102895505A (en) | 2013-01-30 |
| CN102895505B true CN102895505B (en) | 2014-11-05 |
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| CN105943903A (en) * | 2016-05-16 | 2016-09-21 | 英山县人民医院 | Medicine for treating toothache caused by dental caries |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579805A (en) * | 2012-03-23 | 2012-07-18 | 吕海秀 | Mouthwash for treating orthodontic gingivitis |
| CN102600344A (en) * | 2012-03-26 | 2012-07-25 | 贺兰 | Medicine for treating toothache |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579805A (en) * | 2012-03-23 | 2012-07-18 | 吕海秀 | Mouthwash for treating orthodontic gingivitis |
| CN102600344A (en) * | 2012-03-26 | 2012-07-25 | 贺兰 | Medicine for treating toothache |
Non-Patent Citations (5)
| Title |
|---|
| 南京中医药大学.中药大辞典 蛇床子.《中药大辞典 第2版》.上海科学技术出版社,2006,3004-3007. * |
| 口服中药配合超声洁治术治疗牙周炎;黄木兰;《齐齐哈尔医学院学报》;19981231;第19卷(第3期);34 * |
| 朱进忠老中医辨治牙痛经验举隅;李庭凯;《山西中医》;19990831;第15卷(第4期);6-7 * |
| 李庭凯.朱进忠老中医辨治牙痛经验举隅.《山西中医》.1999,第15卷(第4期),6-7. * |
| 黄木兰.口服中药配合超声洁治术治疗牙周炎.《齐齐哈尔医学院学报》.1998,第19卷(第3期),34. * |
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