CN103494953B - Purify the blood capsule and preparation method thereof - Google Patents
Purify the blood capsule and preparation method thereof Download PDFInfo
- Publication number
- CN103494953B CN103494953B CN201310480880.2A CN201310480880A CN103494953B CN 103494953 B CN103494953 B CN 103494953B CN 201310480880 A CN201310480880 A CN 201310480880A CN 103494953 B CN103494953 B CN 103494953B
- Authority
- CN
- China
- Prior art keywords
- parts
- blood
- naja
- hirudo
- scorpio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Purify the blood capsule and preparation method thereof, belongs to treatment hemiplegia technical field of Chinese medicines.Be made up of the dry raw material of following weight portion: Squama Manis scute 1 ~ 2 part, Hirudo 4 ~ 5 parts, Scolopendra 1 ~ 3 part, Scorpio 1 ~ 3 part, Armadillidium 4 ~ 6 parts, Pheretima 4 ~ 6 parts, eupolyphaga 4 ~ 6 parts, Radix Polygoni Multiflori 3 ~ 6 parts, 4 ~ 6 parts, Semen Persicae, Fructus Lycii 3 ~ 6 parts, Naja 1 ~ 4 part, the mass percent of described Naja in total dry raw material is 2% ~ 10%.In preparation method of the present invention, animal drug, through cooking oven dry, is beaten powder and is crossed 100 ~ 200 mesh sieves; Vegetable drug, through carrying out low temperature dewatering, was pulverized 1000 ~ 2000 mesh sieves and was obtained super fine.The capsule that purifies the blood of the present invention can clear up the metabolic waste in blood, purifies the blood, disperse blood stasis and dredge collateral, and promotion of blood circulation, liver heat removing protect brain, can treat Secondary Hyperlipidemia, cerebral atherosclerosis, and the hemiplegia that cerebral embolism causes.
Description
Technical field
Purify the blood capsule and preparation method thereof, belongs to treatment hemiplegia technical field of Chinese medicines.
Background technology
Hemiplegia is hemiplegia again, and refer to the dyskinesia of side upper and lower extremities, facial muscle and lingualis bottom, it is a common sympton of acute cerebrovascular disease.Although slight hemiplegic patient still can be movable, walk, often upper limb flexing, lower limb stretch, and the lower limb of paralysis make a move and draw half circle, and we, this special walking posture, are called hemiplegic gait.
Cause the cause of disease of hemiplegia to have multiple, be mainly divided into the sequela that cerebrovascular causes, as cerebral hemorrhage, cerebral thrombosis, cerebral embolism, brain atrophy, hypertension, hyperlipidemia, craniocerebral trauma, cerebrovascular sclerosis; Nervous system inflammation, damage cause, as " paraplegia " and the myelitis of spinal cord injury; Muscular tissue disease causes, and as progressive muscular dystrophy, amyotrophy, and Post operation causes, as cerebral palsy of children, hydrocephalus, spinal canal stenosis Post operation limbs disturbance.From the cause of disease, the present invention mainly solves: the hemiplegia that cerebral embolism causes.
The hemiplegia that cerebrovascular causes, the symptom such as even to go into a coma as rupture of blood vessel in brain, thromboembolism, spasm etc. cause central nervous system pathological change and dizziness, headache, vomiting, numb limbs and tense tendons, tic, paralysis, unconsciousness occur,, some patients are dead even immediately.Severe patient is often unable to leave the bed, and loses viability, needs family numbers of patients to look after for a long time, cause huge financial burden to patient home.
Though partial Chinese medicine preparation controlled by existence employing Serpentis, Squama Manis in existing Chinese traditional treatment, in the medicament of existing treatment hemiplegia, Serpentis used mostly is nonpoisonous snake as variegated snake; In existing formula, minority adopts poisonous Serpentis, but mostly is as Agkistrodon, Bungarus fasciatus, and the toxicity of Serpentis is too low, snake venom and Serpentis itself less for cerebrovascular effect.And select the consumption of poisonous snake and this patent to there is larger difference in the formula of existing employing Serpentis class treatment hemiplegia.Though there is the design adopting Hirudo in prior art, Hirudo used mostly is in wicker leaf shape, the dark brown trematodiasis of flat back brown-green, and acting on when clearing up blood vessel of this Hirudo is poor.And, the medicine of existing treatment hemiplegia is due to the animal drug containing toxin, as Serpentis, Scolopendra, Scorpio consumption mismatch, with too high toxicity, and hemiplegia disease recovers comparatively slow, patient needs long-term prescription, and Long-term taking medicine easily causes body equilibrium between yin and yang to be destroyed, vivotoxin deposits, and damages internal organs while curing the disease.
Chinese medicine pulverizing is adopted to make the design of capsule in prior art, but because in vegetable drug, cellulose components content is higher, active ingredient is many in the plant cell wall of cellulose composition, cannot play completely, and in prior art when animal drug and vegetable drug collocation treatment hemiplegia, animal drug in capsule is asynchronous with the slow-release time of vegetable drug, the animal drug of interior absorption of human body and vegetable drug amount can not reach balance at one time, designed drug dose collocation is destroyed in the process of being absorbed by the body, and causes curative effect to weaken.
Summary of the invention
The technical problem to be solved in the present invention is: overcome the deficiencies in the prior art, the capsule and preparation method thereof that purifies the blood is provided, this capsule that purifies the blood can clear up endovascular metabolic waste, suppressing the hyperactive liver and subsiding YANG, regulate blood pressure, disperse blood stasis and dredge collateral, promotion of blood circulation, benefiting essence and marrow, promotion neure growth are grown and repair impaired neurocyte, can treat hyperlipidemia, hemiplegia that cerebral atherosclerosis, cerebral embolism cause.
The technical solution adopted for the present invention to solve the technical problems is: this capsule that purifies the blood, is characterized in that, is made up of the dry raw material of following weight portion: Squama Manis scute 1 ~ 2 part, Hirudo 4 ~ 5 parts, Scolopendra 1 ~ 3 part, Scorpio 1 ~ 3 part, Armadillidium 4 ~ 6 parts, Pheretima 4 ~ 6 parts, eupolyphaga 4 ~ 6 parts, Radix Polygoni Multiflori 3 ~ 6 parts, 4 ~ 6 parts, Semen Persicae, Fructus Lycii 3 ~ 6 parts, Naja 1 ~ 4 part, the mass percent of described Naja in total dry raw material is 2% ~ 10%.
Preferably, purify the blood capsule, it is characterized in that, be made up of the raw material of following weight portion: Squama Manis scute 1 part, Hirudo 4 parts, Scolopendra 2 parts, Scorpio 3 parts, Armadillidium 5 parts, Pheretima 5 parts, eupolyphaga 5 parts, Radix Polygoni Multiflori 4 parts, 5 parts, Semen Persicae, Fructus Lycii 4 parts, Naja 2 parts, the mass percent of described Naja in total dry raw material is 5%.
Described Naja is the snakelet of Ophiophagus hannan (Cantor).Described Hirudo is wide Hirudo, and Scolopendra is Gekko Swinhonis, and Scorpio is black Scorpio.
After described Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga and Naja need cook respectively, then dry.
Described Semen Persicae needs slow fire parch, for subsequent use after Radix Polygoni Multiflori and Fructus Lycii adopt crude drug low temperature dewatering.
The preparation method of the capsule that purifies the blood of the present invention, is characterized in that, adopts following steps to obtain:
1) by take by weight Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga and Naja mix and blend, cook, dry, beat powder, cross 100 ~ 200 mesh sieves and obtain animal material powder;
2) by take by weight the parch of Semen Persicae slow fire, drying, pulverizing rear mistake 50 ~ 100 mesh sieve; The Radix Polygoni Multiflori taken by weight and Fructus Lycii are carried out low temperature dewatering, pulverized 1000 ~ 2000 mesh sieves and obtain super fine; Semen Persicae after above-mentioned pulverizing, Radix Polygoni Multiflori and Fructus Lycii are mixed into plant material powder;
3) by animal material powder and plant material powder mixing and stirring, become capsule according to the fill of every 800 ~ 1000mg/ grain and get final product.
The pharmacological property of each compatibe drug adopted in the present invention is as follows:
Squama Manis scute, salty in the mouth; Cold nature, returns liver; Stomach warp, cures mainly blood circulation promoting and dispersing pathogen accumulation; To stimulate the menstrual flow stimulating milk secretion; Eliminating carbuncle is burst hard.Main blood stasis amenorrhea; Lump in the abdomen; Rheumatic arthralgia; Agalactia; Carbuncle; Scrofula.Squama Manis can reduce clotting time, reduce blood viscosity, can clear up lipid metabolism refuse in blood.
Hirudo, property is put down, and salty in the mouth is bitter, enters liver, urinary bladder channel.Cure mainly menstruation apolipsis, lump in the abdomen stomachache, blood-retention, traumatic blood stasis are had a pain, carbuncle erysipelas.Wherein wide Hirudo is compared with brown Hirudo, and in wide Hirudo, hirudin content is higher, reduce whole blood contrast viscosity and plasma viscosity effect more obvious.Wide Hirudo raises in alleviation intracranial pressure, improves local circulation, and the successful recovering function of nervous system aspect is better than brown Hirudo, is more conducive to treatment hemiplegia, cerebral thrombosis and cerebral atherosclerosis.
Scolopendra, nature and flavor are pungent, temperature; Return Liver Channel.Cure mainly endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.
Scorpio, property is put down, sweet in the mouth, removing toxic substances, and anti-inflammatory analgetic, cures mainly and dispel the wind, relieving convulsion, dredging collateral, removing toxic substances.Control infantile convulsion to take out and pluck, epilepsy, apoplexy, hemiplegia, facial hemiparalysis, migraine, rheumatic arthralgia, tetanus, tuberculous lymphadenitis, rubella skin ulcer swells.
Armadillidium, sour in the mouth, temperature, nontoxic puerpera urinate secret.Leprosy can be treated.Effect heat-clearing and toxic substances removing, removing blood stasis with potent drugs, disappear cicatrix.Removing blood stasis, diuretic, removing toxic substances, pain relieving.Control chronic malaria malaria with splenomegaly, amenorrhea lump in the abdomen, urinary obstruction, infantile convulsion locked jaw, ability to speak pain, all skin ulcers of thrush.For relieving sore throat and pain, removing blood stasis with potent drugs diuretic.Control chronic malaria cold and heat, pain, toothache, stomatitis, thrush, laryngopharynx swelling and pain, dysuria, abdominal mass due to blood stasis, Xian, Chi, cold and heat, dredging water passages amenorrhea.
Pheretima, salty in the mouth, cold in nature, return liver, spleen, urinary bladder channel.Heat clearing away, spasmolytic, diuresis, removing toxic substances, cure mainly heat clearing away arresting convulsion, dredging collateral, relievings asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.Pheretima can thrombolytic and anticoagulation, reduces blood pressure.
Eupolyphaga, cold in nature, salty in the mouth, returns Liver Channel.Cure mainly removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.Eupolyphaga Seu Steleophaga has blood coagulation resisting function, can improve and the blood supply of major organs, tissue and whole body in reinforcement, heart be had to the effect of pumping function simultaneously, can improve cerebral ischemia, dredging cerebral vessels.
Radix Polygoni Multiflori, property is sweet, puckery, bitter in the mouth; Slightly warm in nature, returns liver, kidney channel; Cure mainly blood deficiency anemia; Light-headedness; Cardiopalmus; Insomnia; The soreness of the waist and knees of the hepatic and renal YIN deficiency; Early whitening of beard and hair; Tinnitus; Seminal emission; Dryness of the intestine constipation; Chronic malaria body is empty; Rubella pruritus; Carbuncle sore; Scrofula; Hemorrhoid.
Semen Persicae, property is sweet, flat, bitter in the mouth, GUIXIN, liver, large intestine channel.Cure mainly blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.For amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.Semen Persicae has vasodilator effect, can increase blood flow volume and reduce vascular resistance, having direct dilating effect to blood vessel wall, also having and suppress blood coagulation and haemolysis.
Fructus Lycii, nature and flavor are put down, sweet in the mouth, hardship, sweet.Nourishing the liver, nourishing kidney, lung moistening, tonify deficiency.Nourishing the liver; Nourishing kidney; Lung moistening, cures mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual unclear; Soreness of the waist and knees; Impotence and seminal emission; Cough due to consumptive disease; To quench one's thirst taking fluids profusely.
Naja, sweet-salty, warm in nature, poisonous; Enter liver, kidney two warp; Cure mainly expelling wind and removing dampness.Dispelling the wind and dampness pathogens arthralgia.Cobra venom is the admixture poison based on Nervous toxicity to human or animal, and low concentration cobra venom can cause respiratory stimulant, makes contractile force strengthen accelerating, extends clotting time, stimulate peripheral nerve, recover neuronic conduction function.
The capsule and preparation method thereof that purifies the blood of the present invention adopts organizes drug combination more, and cooperatively interact between medicine group and group, collaborative promotion, improves overall drug effect.
Pheretima, Armadillidium, Naja and Semen Persicae, Radix Polygoni Multiflori coupling, can increase blood flow, dredging brain thromboembolism position, lipid metabolism refuse in cleaning blood, calm nerves, can alleviate the side effect that cobratoxin brings simultaneously and improve drug effect.
Squama Manis scute, Hirudo, eupolyphaga, Fructus Lycii coupling can improve hepatic and renal function, strengthen Liver and kidney to the clean-up effect of blood, the deposition of thrombosis, formation in preclude blood, applicant think cerebral atherosclerosis, hemiplegia, cerebral thrombosis main cause be in blood metabolic waste deposition, but its basic reason is body heart, liver, kidney organ weakness cause
The toxicity of Ophiophagus hannan (Cantor) snakelet toxin is higher than the toxin toxicity becoming Serpentis, and toxic components is abundanter.Use the treatment of Ophiophagus hannan (Cantor) snakelet.The capsule that purifies the blood of the present invention adopts animal material and plant material to arrange in pairs or groups, and promotion of blood circulation, benefiting essence and marrow, promotion neure growth are grown and repair impaired neurocyte.
The preparation method of the capsule that purifies the blood of the present invention, by animal material and plant material separately process, animal drug, through cooking oven dry, is beaten powder and is crossed 100 ~ 200 mesh sieves; Vegetable drug, through carrying out low temperature dewatering, was pulverized 1000 ~ 2000 mesh sieves and was obtained super fine, and can make more the breaking of cell wall in Radix Polygoni Multiflori, Semen Persicae, Fructus Lycii, make effective ingredient in cell be convenient to absorption of human body.But botanical pulverizes and sieves order number is not easily greater than 2000 orders.Plant row medical material is easily caused to absorb too fast in vivo when mistake grit number after Radix Polygoni Multiflori, Semen Persicae, Fructus Lycii super fine is greater than 2000 orders, botanical (Radix Polygoni Multiflori, Semen Persicae, the Fructus Lycii) excessive concentration absorbed in blood and animality medical material haemoconcentration are arranged in pairs or groups bad, vegetable drug and animal drug absorb uneven, decline to blood intracellular metabolite product cleaning effect, drug effect weakens.
Compared with prior art, the beneficial effect that the capsule and preparation method thereof and preparation method thereof that purifies the blood of the present invention has is:
1, the capsule that the purifies the blood of the present invention capsule that can purify the blood can clear up metabolic waste in blood, and purify the blood, the liver and the kidney tonifying, heart tonifying protects brain, and promotion of blood circulation, benefiting essence and marrow, promotion neure growth are grown and repair impaired neurocyte.
Cleaning blood then needs promotion of blood circulation, and reduce the metabolic waste deposition in the blood vessel in blood, be rich in a large amount of mineral and nutrient protein in the animal raw materials of the capsule that purifies the blood, nutrition is caught up with, and venation one is opened, and all problems is all readily solved.Give nutrition again, disperse blood stasis and dredge collateral soup is to lead to for use, and brain, concora crush YANG hyperactivity suppressing, blood circulation promoting and blood stasis dispelling are protected in liver heat removing, benefiting essence and marrow is rapid-action and have no side effect, and are applicable to all groups, also can be used as blood health care medicine and uses.
Applicant finds after deliberation: hyperlipemia, atherosclerosis and its hemiplegia caused cause because of waste deposits in blood, and only the simple treatment carrying out dredging, softening for blood vessel cannot effect a radical cure disease, and blood spreads all over human body.Cleaning, purify the blood in metabolic waste, keep the youth of blood, can protect blood vessel, then all diseases are all separated.
2, because the Radix Polygoni Multiflori in the present invention, Semen Persicae, Fructus Lycii are vegetable raw material, under the parcel of cell wall, effective ingredient is difficult to absorbing by greater efficiency in human body.At vegetable raw material with when to balance the animal raw materials conbined usage of dose in theory, botanical absorbance is lower than animality medical material, reality is difficult at the systemic effective ingredient of human body the balance reaching recipe design, and long-term taking easily produces harmful effect to the body constitution of patient.In the preparation method of the capsule that purifies the blood of the present invention, adopt and animality medical material and botanical are separately pulverized, animal drug, through cooking oven dry, is beaten powder and is crossed 100 ~ 200 mesh sieves; Vegetable drug, through carrying out low temperature dewatering, was pulverized 1000 ~ 2000 mesh sieves and was obtained super fine, and can make more the breaking of cell wall in Radix Polygoni Multiflori, Semen Persicae, Fructus Lycii, make effective ingredient in cell be convenient to absorption of human body.The capsule drug effect that purifies the blood of the present invention can be improved in above process, purify the blood capsule in vivo in slow release the absorption of plant material and animal material effective ingredient can reach balance, both solve botanical and absorbed problem slowly, eliminate again animality medical material to the side effect of human body.
Detailed description of the invention
Embodiment 1 ~ 5 is specific embodiments of the capsule and preparation method thereof and preparation method thereof that purifies the blood of the present invention, and wherein embodiment 1 is preferred forms.
embodiment 1
Squama Manis scute 1 part, Hirudo 4 parts, Scolopendra 2 parts, Scorpio 3 parts, Armadillidium 5 parts, Pheretima 5 parts, eupolyphaga 5 parts, Radix Polygoni Multiflori 4 parts, 5 parts, Semen Persicae, Fructus Lycii 4 parts, Naja 2 parts.The mass percent of Naja in total dry raw material is 5%.
In the present embodiment, Hirudo is wide Hirudo, and Scolopendra is Gekko Swinhonis, and Scorpio is black Scorpio, and Naja is the snakelet of Ophiophagus hannan (Cantor).
The preparation method of the capsule that purifies the blood of the present embodiment, adopts following steps to obtain:
1) by take by weight Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga and Naja mix and blend, cook, dry, beat powder, cross 100 mesh sieves and obtain animal material powder;
2) by take by weight the parch of Semen Persicae slow fire, drying, pulverizing rear mistake 100 mesh sieve; The Radix Polygoni Multiflori taken by weight and Fructus Lycii are carried out low temperature dewatering, pulverized 1000 mesh sieves and obtain super fine; Semen Persicae after above-mentioned pulverizing, Radix Polygoni Multiflori and Fructus Lycii are mixed into plant material powder;
3) by animal material powder and plant material powder mixing and stirring, become capsule according to the fill of every 800 ~ 1000mg/ grain and get final product.
embodiment 2
Squama Manis scute 2 parts, Hirudo 4 parts, Scolopendra 3 parts, Scorpio 2 parts, Armadillidium 4 parts, Pheretima 5 parts, eupolyphaga 4 parts, Radix Polygoni Multiflori 3 parts, 5 parts, Semen Persicae, Fructus Lycii 6 parts, Naja 3 parts, the mass percent of Naja in total dry raw material is 7.3%.
In the present embodiment, Hirudo is wide Hirudo, and Scolopendra is Gekko Swinhonis, and Scorpio is black Scorpio, and Naja is the snakelet of Ophiophagus hannan (Cantor).
The preparation method of the capsule that purifies the blood of the present embodiment, adopts following steps to obtain:
1) by take by weight Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga and Naja mix and blend, cook, dry, beat powder, cross 100 mesh sieves and obtain animal material powder;
2) by take by weight the parch of Semen Persicae slow fire, drying, pulverizing rear mistake 50 mesh sieve; The Radix Polygoni Multiflori taken by weight and Fructus Lycii are carried out low temperature dewatering, pulverized 1000 mesh sieves and obtain super fine; Semen Persicae after above-mentioned pulverizing, Radix Polygoni Multiflori and Fructus Lycii are mixed into plant material powder;
3) by animal material powder and plant material powder mixing and stirring, become capsule according to the fill of every 800 ~ 1000mg/ grain and get final product.
embodiment 3
Squama Manis scute 1 part, Hirudo 5 parts, Scolopendra 3 parts, Scorpio 2 parts, Armadillidium 6 parts, Pheretima 6 parts, eupolyphaga 4 parts, Radix Polygoni Multiflori 3 parts, 4 parts, Semen Persicae, Fructus Lycii 6 parts, Naja 2.5 parts, the mass percent of Naja in total dry raw material is 5.9%.
In the present embodiment, Hirudo is wide Hirudo, and Scolopendra is Gekko Swinhonis, and Scorpio is black Scorpio, and Naja is the snakelet of Ophiophagus hannan (Cantor).
The preparation method of the capsule that purifies the blood of the present embodiment, adopts following steps to obtain:
1) by take by weight Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga and Naja mix and blend, cook, dry, beat powder, cross 100 mesh sieves and obtain animal material powder;
2) by take by weight the parch of Semen Persicae slow fire, drying, pulverizing rear mistake 100 mesh sieve; The Radix Polygoni Multiflori taken by weight and Fructus Lycii are carried out low temperature dewatering, pulverized 1000 mesh sieves and obtain super fine; Semen Persicae after above-mentioned pulverizing, Radix Polygoni Multiflori and Fructus Lycii are mixed into plant material powder;
3) by animal material powder and plant material powder mixing and stirring, become capsule according to the fill of every 800 ~ 1000mg/ grain and get final product.
embodiment 4
Squama Manis scute 1 part, Hirudo 4 parts, Scolopendra 2 parts, Scorpio 2 parts, Armadillidium 5 parts, Pheretima 4 parts, eupolyphaga 6 parts, Radix Polygoni Multiflori 6 parts, 5 parts, Semen Persicae, Fructus Lycii 4 parts, Naja 1 part, the mass percent of Naja in total dry raw material is 2.5%.
In the present embodiment, Hirudo is wide Hirudo, and Scolopendra is Gekko Swinhonis, and Scorpio is black Scorpio, and Naja is the snakelet of Ophiophagus hannan (Cantor).
The preparation method of the capsule that purifies the blood of the present embodiment, is characterized in that, adopts following steps to obtain:
1) by take by weight Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga and Naja mix and blend, cook, dry, beat powder, cross 100 mesh sieves and obtain animal material powder;
2) by take by weight the parch of Semen Persicae slow fire, drying, pulverizing rear mistake 100 mesh sieve; The Radix Polygoni Multiflori taken by weight and Fructus Lycii are carried out low temperature dewatering, pulverized 1000 mesh sieves and obtain super fine; Semen Persicae after above-mentioned pulverizing, Radix Polygoni Multiflori and Fructus Lycii are mixed into plant material powder;
3) by animal material powder and plant material powder mixing and stirring, become capsule according to the fill of every 800 ~ 1000mg/ grain and get final product.
embodiment 5
Squama Manis scute 2 parts, Hirudo 5 parts, Scolopendra 2 parts, Scorpio 1 part, Armadillidium 6 parts, Pheretima 4 parts, eupolyphaga 5 parts, Radix Polygoni Multiflori 3 parts, 6 parts, Semen Persicae, Fructus Lycii 6 parts, Naja 4 parts, the mass percent of Naja in total dry raw material is 9%.
In the present embodiment, Hirudo is wide Hirudo, and Scolopendra is Gekko Swinhonis, and Scorpio is black Scorpio, and Naja is the snakelet of Ophiophagus hannan (Cantor).
The preparation method of the capsule that purifies the blood of the present embodiment, adopts following steps to obtain:
1) by take by weight Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga and Naja mix and blend, cook, dry, beat powder, cross 100 mesh sieves and obtain animal material powder;
2) by take by weight the parch of Semen Persicae slow fire, drying, pulverizing rear mistake 50 mesh sieve; The Radix Polygoni Multiflori taken by weight and Fructus Lycii are carried out low temperature dewatering, pulverized 1000 mesh sieves and obtain super fine; Semen Persicae after above-mentioned pulverizing, Radix Polygoni Multiflori and Fructus Lycii are mixed into plant material powder;
3) by animal material powder and plant material powder mixing and stirring, become capsule according to the fill of every 800 ~ 1000mg/ grain and get final product.
clinical practice is summed up
The medicable disease of the present invention and cardinal symptom as follows
Cerebral atherosclerosis: brains is uncomfortable, often thinks that hair is heavy, stuffy, dizzy, headache, often with tinnitus, and blurring of vision.Sleep bad, nearly hypomnesis, comprehensive descision ability declines, emotional, flies into a rage, sad, anxious state of mind is large, and the performance of personality abnormality, of short duration numb limbs and tense tendons, walks and turn round slow, stiff or unstable.
The hemiplegia that cerebrovascular causes: dizzy, headache, vomiting, numb limbs and tense tendons, twitch, paralysis, unconsciousness, mouth eye fish sticking its mouth out of the water tiltedly, aphasis, slobbering, dysphagia.Upper limb flexing when walking, lower limb stretch, and the lower limb of paralysis make a move and draw half circle.
Secondary Hyperlipidemia: dizzy weak, inappetence, impatiently ischemia, shortness of breath and palpitation, the xanthoma caused by lipid deposits in intradermal and lipid deposit at blood vessel endothelium
Cerebral embolism: in the present invention for cerebral embolism be arteriae cerebri thromboembolism, the sensation of focus offside lower limb and the dyskinesia, offside central facial palsy, lingualis paralysis and upper extremity palsy, hemidysesthesia and hemianopsia, also mental disorder and the forced grasping reflexs such as apathy, glad can be there is, aphasia, sensory aphasia, alexia, logagraphia.
Of the present invention purify the blood capsule adopt oral, the hemiplegia that cerebrovascular causes and cerebral embolism be grown up one time 2 ~ 3,3 ~ 4 times on the one; Cerebral atherosclerosis one time 2,3 ~ 4 times on the one; Secondary Hyperlipidemia one time 1,3 ~ 4 times on the one; Continuous use 60 days is 1 course for the treatment of; Quit smoking, wine, greasy food (fried, food rich in fat), anemia of pregnant woman forbid.
Curative effect judging standard: curative effect is divided into healing according to the improvement situation of above-mentioned symptom, takes a turn for the better and do not heal, use in the course for the treatment of described in effective effect according to aforementioned disorders classification, total effective rate is cure rate and improvement rate sum.Continuous use is of the present invention to purify the blood after 4 ~ 5 courses for the treatment of of capsule and preparation method thereof and adds up, and statistical result is as shown in table 1.
Table 1 the present invention purify the blood capsule case statistics
Take in 4 ~ 5 courses for the treatment of, recovery from illness number of cases 3185 example, the effective example of effective number of cases, total effectively number of cases 3390 example, total effective rate 92%, cure rate 87%.
comparative example 1
In this comparative example, component proportion is identical with embodiment 1, the preparation method of the capsule that purifies the blood of this comparative example, employing following steps obtain: by take by weight Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga, Naja, Radix Polygoni Multiflori and Fructus Lycii mix and blend, cook, dry, beat powder, cross 100 mesh sieves and obtain material powder; Become capsule according to the fill of every 1000mg/ grain and get final product.
After comparative example 1 uses 1 course for the treatment of, have the patient of 2% to occur the untoward reaction of insomnia, irritability, after drug withdrawal, symptom disappears immediately, and drug withdrawal adopts embodiment 1 to carry out treating after 2 weeks, occur without any untoward reaction.
comparative example 2
Component proportion in this comparative example, raw material pre-treatment are identical with embodiment 1, the preparation method of the capsule that purifies the blood of this comparative example, employing following steps obtain: by take by weight Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga, Naja, Radix Polygoni Multiflori and Fructus Lycii mix and blend, cook, dry, beat powder, cross 2000 mesh sieves and obtain ultra-fine feed stock powder; Become capsule according to the fill of every 800mg/ grain and get final product.
In 1 week that comparative example 2 ~ 3 uses, have the patient of 1% to have dizzy symptom, after drug withdrawal, symptom disappears immediately, and drug withdrawal adopts embodiment 1 to carry out treating after 2 weeks, occur without any untoward reaction.
comparative example 3
Squama Manis in this comparative example, Hirudo, Scolopendra, Scorpio, Pheretima, eupolyphaga, Radix Polygoni Multiflori, Semen Persicae are identical with embodiment 1 with Fructus Lycii consumption, and in this comparative example, Naja is 5 parts.The mass percent of Naja in total dry raw material is 13.5%.
In this comparative example, preparation method is identical with embodiment 1.
In 1 week that comparative example 3 uses, have the patient of 15% to have rapid breathing, dizzy symptom, after drug withdrawal, symptom disappears immediately, and drug withdrawal adopts embodiment 1 to carry out treating after 2 weeks, occur without any untoward reaction.Dizziness person 95% be sun heat, with hypertensive patient; Occur that rapid breathing patient 98% is the empty patient of body of long-term hemiplegia.Naja consumption is excessive to stimulate by force to nervous system and blood flow, and hemiplegia patient activity measures reduction, how with body void, cerebral thrombosis, cerebral atherosclerosis patient many with the heart, liver, suffer from a deficiency of the kidney weak; And the treatment of hemiplegia, cerebral thrombosis, cerebral atherosclerosis and Secondary Hyperlipidemia is slow, need Long-term taking medicine, Naja consumption crosses multipair patient body to stimulate comparatively large, is not easy to long-term treatment.
comparative example 4
Squama Manis in this comparative example, Hirudo, Scolopendra, Scorpio, Pheretima, eupolyphaga, Radix Polygoni Multiflori, Semen Persicae are identical with embodiment 1 with Fructus Lycii consumption, for: Squama Manis scute 1 part, Hirudo 4 parts, Scolopendra 2 parts, Scorpio 3 parts, Armadillidium 5 parts, Pheretima 5 parts, eupolyphaga 5 parts, Radix Polygoni Multiflori 4 parts, 5 parts, Semen Persicae, Fructus Lycii 4 parts, in this comparative example, Naja is 0.5 part.The mass percent of Naja in total dry raw material is 1.3%.
In this comparative example, preparation method is identical with embodiment 1.
After using 4 ~ 5 courses for the treatment of: this comparative example total effective rate 78%, cure rate 58%.Can Naja consumption to be too small stimulated excessively weak to nervous system and blood flow, therapeutic effect is too low.
comparative example 5
In this comparative example, component proportion and preparation method are all identical with embodiment 1, and wherein Hirudo used is wide Hirudo, and Scolopendra is Gekko Swinhonis, and Scorpio is black Scorpio, and Naja is the one-tenth Serpentis of Ophiophagus hannan (Cantor).
After using 4 ~ 5 courses for the treatment of: this comparative example total effective rate 52%, cure rate 25%.Comparative example 5 total effective rate 46%, cure rate 17%.Use Ophiophagus hannan (Cantor) snakelet cure rate apparently higher than the cure rate using Ophiophagus hannan (Cantor) to become Serpentis in visible embodiment.Ophiophagus hannan (Cantor) snakelet toxic components is compared to one-tenth Serpentis more horn of plenty, better to blood cleaning effect, more excellent to neural stimulation, repairing effect.
comparative example 6
Squama Manis scute 1 part, Hirudo 3 parts, Scolopendra 2 parts, Scorpio 3 parts, Armadillidium 5 parts, Pheretima 5 parts, eupolyphaga 5 parts, Radix Polygoni Multiflori 4 parts, Semen Persicae Fructus Lycii 4 parts, Agkistrodon 2 parts.In this comparative example, preparation method is identical with embodiment 1.
After using 4 ~ 5 courses for the treatment of: this comparative example total effective rate 49%, cure rate 21%.Use the cure rate of Ophiophagus hannan (Cantor) apparently higher than the cure rate using Agkistrodon in visible embodiment.
comparative example 7
In this comparative example, component proportion and preparation method are all identical with embodiment 1, and wherein Hirudo used is brown Hirudo, and Scolopendra is Gekko Swinhonis, and Scorpio is black Scorpio, and Naja is the snakelet of Ophiophagus hannan (Cantor).
After using 4 ~ 5 courses for the treatment of: this comparative example total effective rate 46%, cure rate 17%.Use the cure rate of wide Hirudo apparently higher than the cure rate using brown Hirudo in visible embodiment.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.。
Claims (4)
1. purify the blood capsule, it is characterized in that, is made up of the dry raw material of following weight portion: Squama Manis scute 1 part, Hirudo 4 parts, Scolopendra 2 parts, Scorpio 3 parts, Armadillidium 5 parts, Pheretima 5 parts, eupolyphaga 5 parts, Radix Polygoni Multiflori 4 parts, 5 parts, Semen Persicae, Fructus Lycii 4 parts, Naja 2 parts, the mass percent of described Naja in total dry raw material is 5%; Described Naja is the snakelet of Ophiophagus hannan (Cantor), and described Hirudo is wide Hirudo, and Scolopendra is Gekko Swinhonis, and Scorpio is black Scorpio;
Described Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga and Naja mix and blend, cook, dry, beat powder, crosses 100 ~ 200 mesh sieves;
Described Semen Persicae slow fire parch, drying, pulverizing rear mistake 50 ~ 100 mesh sieve;
Described Radix Polygoni Multiflori and Fructus Lycii carry out low temperature dewatering, pulverize 1000 ~ 2000 mesh sieves and obtain super fine.
2. the capsule that purifies the blood according to claim 1, is characterized in that: after described Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga and Naja need cook respectively, then dry.
3. the capsule that purifies the blood according to claim 1, is characterized in that: described Semen Persicae is through slow fire parch, for subsequent use after Radix Polygoni Multiflori and Fructus Lycii adopt crude drug low temperature dewatering.
4. purify the blood the preparation method of capsule, it is characterized in that, adopts following steps to obtain:
1) by take by weight Squama Manis scute, Hirudo, Scolopendra, Scorpio, Armadillidium, Pheretima, eupolyphaga and Naja mix and blend, cook, dry, beat powder, cross 100 ~ 200 mesh sieves and obtain animal material powder;
2) by take by weight the parch of Semen Persicae slow fire, drying, pulverizing rear mistake 50 ~ 100 mesh sieve; The Radix Polygoni Multiflori taken by weight and Fructus Lycii are carried out low temperature dewatering, pulverized 1000 ~ 2000 mesh sieves and obtain super fine; Semen Persicae after above-mentioned pulverizing, Radix Polygoni Multiflori and Fructus Lycii are mixed into plant material powder;
3) by animal material powder and plant material powder mixing and stirring, become capsule according to the fill of every 800 ~ 1000mg/ grain and get final product;
Described Squama Manis scute 1 part, Hirudo 4 parts, Scolopendra 2 parts, Scorpio 3 parts, Armadillidium 5 parts, Pheretima 5 parts, eupolyphaga 5 parts, Radix Polygoni Multiflori 4 parts, 5 parts, Semen Persicae, Fructus Lycii 4 parts, Naja 2 parts, the mass percent of described Naja in total dry raw material is 5%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310480880.2A CN103494953B (en) | 2013-10-15 | 2013-10-15 | Purify the blood capsule and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310480880.2A CN103494953B (en) | 2013-10-15 | 2013-10-15 | Purify the blood capsule and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103494953A CN103494953A (en) | 2014-01-08 |
| CN103494953B true CN103494953B (en) | 2015-11-11 |
Family
ID=49860276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310480880.2A Expired - Fee Related CN103494953B (en) | 2013-10-15 | 2013-10-15 | Purify the blood capsule and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103494953B (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1290532A (en) * | 2000-09-26 | 2001-04-11 | 袁曙光 | Method for preparing Chinese medicine for curing apoplexy and hemiparalysis |
| CN1411845A (en) * | 2001-10-08 | 2003-04-23 | 靖卫星 | Oral Chinese medicine for curing cerebrovascular disease |
| CN1861171A (en) * | 2006-04-18 | 2006-11-15 | 钟龙 | Method for preparing traditional Chinese medicine to treat apoplexia hemiplegia and said medicine |
| CN102920922A (en) * | 2012-11-16 | 2013-02-13 | 李清元 | Magically effective bone pain pill |
-
2013
- 2013-10-15 CN CN201310480880.2A patent/CN103494953B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1290532A (en) * | 2000-09-26 | 2001-04-11 | 袁曙光 | Method for preparing Chinese medicine for curing apoplexy and hemiparalysis |
| CN1411845A (en) * | 2001-10-08 | 2003-04-23 | 靖卫星 | Oral Chinese medicine for curing cerebrovascular disease |
| CN1861171A (en) * | 2006-04-18 | 2006-11-15 | 钟龙 | Method for preparing traditional Chinese medicine to treat apoplexia hemiplegia and said medicine |
| CN102920922A (en) * | 2012-11-16 | 2013-02-13 | 李清元 | Magically effective bone pain pill |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103494953A (en) | 2014-01-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104606352A (en) | Bone tuberculosis treating compound pill | |
| CN104825801A (en) | TCM (traditional Chinese medicine) preparation for preventing and treating cardiovascular and cerebrovascular diseases | |
| CN104436018A (en) | Medicine for treating tumors and preparation method thereof | |
| CN104623433A (en) | Traditional Chinese medicine for preventing postanesthesia shivering and preparation method of traditional Chinese medicine | |
| CN107412640B (en) | External ointment for assisting acupuncture and moxibustion physiotherapy | |
| CN104547574A (en) | Traditional Chinese medicine for treating kidney deficiency | |
| CN103494953B (en) | Purify the blood capsule and preparation method thereof | |
| CN103800822B (en) | Be used for the treatment of the Chinese medicine composition of hypertensive cerebral hemorrhage | |
| CN103120769A (en) | Medicine for treating cerebral circulation insufficiency | |
| CN106668646A (en) | Traditional Chinese medicine for treating chicken egg yield reduction | |
| CN106511945A (en) | Medicine for treating insomnia and preparation method thereof | |
| CN102895392B (en) | Chinese medicine for treating duodenal ulcer | |
| CN103585431B (en) | Traditional Chinese medicine composition for curing type I diabetes mellitus | |
| CN103961657A (en) | External traditional Chinese medicinal powder used for treating trauma | |
| CN103656294B (en) | Medicine for treating acute glomerulonephritis and preparation method thereof | |
| CN105943999A (en) | Pharmaceutical composition for treating wind-phlegm collateral obstruction type ischemic stroke | |
| CN103816521A (en) | Chinese medicament for treating tetanus with syndrome of wind-toxicity invading collaterals | |
| CN105434987A (en) | Traditional Chinese medicine preparation for treating cerebral infarction | |
| CN105343582A (en) | Medicine for treating tetanus and preparation method thereof | |
| CN105311578A (en) | Traditional Chinese medicine composition for treating intracranial tumors | |
| CN105213667A (en) | A kind of medicine for the treatment of hemiplegia and preparation method thereof | |
| CN104435738A (en) | Traditional Chinese medicine composition for treating narcolepsy caused by deficiency of spleen qi syndrome | |
| CN103656589A (en) | Drug for treating viral myocarditis and preparation method thereof | |
| CN103479956A (en) | Preparation method of traditional Chinese medicine with function of reinforcing spleen to promote digestion | |
| CN113855777A (en) | External Chinese herbal medicine fire-free moxibustion preparation for dredging channels and collaterals and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151111 Termination date: 20191015 |