CN103476252B - 吡唑基胍f1f0‑atp酶抑制剂及其治疗用途 - Google Patents

吡唑基胍f1f0‑atp酶抑制剂及其治疗用途 Download PDF

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CN103476252B
CN103476252B CN201180065940.3A CN201180065940A CN103476252B CN 103476252 B CN103476252 B CN 103476252B CN 201180065940 A CN201180065940 A CN 201180065940A CN 103476252 B CN103476252 B CN 103476252B
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CN103476252A (zh
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G·D·格利克
A·R·赫德
C·B·泰勒
C·A·范于斯
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Lycera Corp
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CN201180065940.3A 2010-12-08 2011-12-08 吡唑基胍f1f0‑atp酶抑制剂及其治疗用途 Expired - Fee Related CN103476252B (zh)

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US42095010P 2010-12-08 2010-12-08
US61/420,950 2010-12-08
PCT/US2011/063950 WO2012078874A1 (en) 2010-12-08 2011-12-08 Pyrazolyl guanidine f1f0-atpase inhibitors and therapeutic uses thereof

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ES2639439T3 (es) 2010-12-08 2017-10-26 Lycera Corporation Inhibidores de F1F0-ATPasas de tipo pirazolilguanidina y sus usos terapéuticos de éstos
ES2591156T3 (es) 2010-12-08 2016-11-25 Lycera Corporation Inhibidores de F1F0-ATPasas de tipo piridonil guanidina y sus usos terapéuticos
US9169199B2 (en) 2010-12-08 2015-10-27 Lycera Corporation Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof
EP2866893A4 (en) 2012-06-08 2015-12-23 Lycera Corp HETEROCYCLIC GUANIDINE F1FO ATPASE INHIBITORS
US9920012B2 (en) 2012-06-08 2018-03-20 Lycera Corporation Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof
US9580391B2 (en) 2012-06-08 2017-02-28 Lycera Corporation Saturated acyl guanidine for inhibition of F1F0-ATPase
WO2015089149A1 (en) * 2013-12-10 2015-06-18 Lycera Corporation Trifluoromethyl pyrazolyl guanidine f1fo-atpase inhibitors and therapeutic uses thereof
AU2014363907B2 (en) * 2013-12-10 2018-10-04 Lycera Corporation N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof
WO2015089131A1 (en) * 2013-12-10 2015-06-18 Lycera Corporation Alkylpyrazolyl guanidine f1f0-atpase inhibitors and therapeutic uses thereof
WO2017135399A1 (ja) * 2016-02-04 2017-08-10 塩野義製薬株式会社 ＴｒｋＡ阻害活性を有する含窒素複素環および炭素環誘導体

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WO2010030891A2 (en) * 2008-09-11 2010-03-18 The Regents Of The University Of Michigan Aryl guanidine f1f0-atpase inhibitors and related methods
CN101855203A (zh) * 2007-09-14 2010-10-06 密执安州立大学董事会 F1f0-atp合成酶抑制剂以及相关的方法

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