Background technology
The sickness rate of China's diabetes is up to 9.7% at present, and number of patients is 9,700 ten thousand people approximately, at present also in the speed increase with example every days 3,000., according to World Health Organization's statistics, showing, the annual Diabetes Death number in the world is seven million peoples, with regard to a dead example, just have a diabetics every 30 seconds by amputation average every ten seconds.The current ill total number of persons of China has surmounted the U.S., and India becomes the first in the world.Diabetes as worldwide difficult medical problem due to very complicated method, the especially complication that not there is no so far radical cure of its pathogenesis, hard to guard against especially, fatality rate, the height of disability rate ranks front three.According to up-to-date diabetes study, show, the pathogenesis traditional Chinese medical science of diabetes is thought and is caused by the human body deficiency of both QI and YIN from strategic height, should be caused by the deficiency of vital energy more precisely, only have the deficiency of vital energy just to match with " The Yellow Emperor's Canon of Internal Medicine " the five internal organs pathogenesis, according to " Huang di's Canon of Medicine ", " TCM basis theory ", " Chinese materia medica ", " Compendium of Materia Medica ", " diabetology " and other scientific theories are for instructing, in fact the traditional Chinese medical science has superiority in diabetes control, health therapy for diabetes and complication thereof can solve by dietetic therapy, by studying on pure book on Chinese herbal medicine, collection food, health product, medicine is integrated, improve the prevention of Chinese medicine, health care, therapeutic effect.
According to diabetology, studies show that, through zoopery, show to have 54 kinds of Chinese herbal medicine to there is hypoglycemic activity, end the Chinese medicine that in December, 2007 state food drug surveilance office examines the treatment diabetes of promulgation and amount to 35 kinds, relate to pill, capsule, oral liquid, granule, tablet, 6 kinds of dosage forms of injection, wherein only a kind of is the effective ingredient extracted from Chinese medicine.
According to up-to-date diabetology research, show, Chinese medicinal plant composition with hypoglycemic activity mainly contains: terpenoid, insulin, peptide and amino acids, flavonoid, polysaccharide, the thioether class, alkaloids, Coumarins and unsaturated fatty acids etc., they bring into play curative effect by approach and the target spot do not allowed in the treatment of diabetes, but these effective chemicals, under hot conditions, most of destroyed goods is inactivated, in the high quality liquor at 50---53 degree ethanol content, room temperature is molten gets, the activity of these materials and concentration are quite high, its hypoglycemic effect is poor unlike Western medicine, and toxic and side effects is little, and there is the effect effected a permanent cure.
Summary of the invention
According to above-mentioned elaboration, the object of the present invention is to provide and can play and regulate equilibrium between yin and yang and there is a kind for the treatment of of auxiliary hyperglycemic effect and the medicated wine of health-care effect diabetics.
The technical scheme of a kind of healthy medicated wine provided by the invention has following component at the wine of 3000 grams~30000 grams:
Rhizoma Gastrodiae 50 grams~200 grams; Radix Angelicae Sinensis 100 grams~200 grams; Radix Rehmanniae Preparata 30 grams~150 grams; Radix Polygoni Multiflori 30 grams~150 grams; Semen Cassiae 50 grams~200 grams; Radix Ophiopogonis 30 gram~100 grams; The Rhizoma Atractylodis Macrocephalae 30 grams~100 grams; Fructus Lycii 150 grams~300 grams; Radix Salviae Miltiorrhizae 30 grams~100 grams, Radix Polygalae 50 grams~200 grams, Rhizoma Polygonati 100 grams~200 grams.
In the preferred version of such scheme, at the wine of 3000 grams~30000 grams, following component is arranged:
Rhizoma Gastrodiae 80 grams~150 grams; Radix Angelicae Sinensis 120 grams~180 grams; Radix Rehmanniae Preparata 50 grams~120 grams; Radix Polygoni Multiflori 50 grams~100 grams; Semen Cassiae 100 grams~180 grams; Radix Ophiopogonis 40 gram~80 grams; The Rhizoma Atractylodis Macrocephalae 40 grams~70 grams; Fructus Lycii 180 grams~280 grams; Radix Salviae Miltiorrhizae 40 grams~70 grams, Radix Polygalae 80 grams~150 grams, Rhizoma Polygonati 120 grams~180 grams.
In the preferred version of such scheme, at the wine of 3000 grams~30000 grams, following component is arranged:
Rhizoma Gastrodiae 90 grams~120 grams; Radix Angelicae Sinensis 140 grams~150 grams; Radix Rehmanniae Preparata 80 grams~100 grams; Radix Polygoni Multiflori 50 grams~80 grams; Semen Cassiae 130 grams~150 grams; Radix Ophiopogonis 50 gram~60 grams; The Rhizoma Atractylodis Macrocephalae 50 grams~60 grams; Fructus Lycii 240 grams~250 grams; Radix Salviae Miltiorrhizae 50 grams~60 grams, Radix Polygalae 90 grams~120 grams, Rhizoma Polygonati 150 grams~170 grams.
The pure grain wine that described wine is 40~60 degree, as one of in corn wine, Sorghum vulgare Pers. Wine, buckwheat wine, little ale, barley broo.
The preparation method of medicated wine provided by the invention is:
Described component is inserted in the pure grain wine of 40~60 degree, room temperature sealing is placed 30-50 days.
The present invention utilizes soaking in Chinese liquor Chinese medicine processed, reach collection food, health product, the integrated effect of medicine, Chinese medicine is passed through to soaking in Chinese liquor, utilize the superpower permeability of ethanol, the residence medicine is in wine, wine helps the property of medicine, greatly improve the practicality of Chinese medicine, dissolve a herbal nature difficult problem slowly, give full play to the guiding drug function of wine, strengthen targeting, nutrient substance abundant in wild Chinese herbal medicine is separated out, the collection edible wine, health promoting wine, treatment wine is in one, the pharmacy mode of the traditional Chinese medical science is constantly developed, this medicated wine be take oral as main, this medicated wine manufacture method is simple, raw material is easy to get, and cost is low, multiple functional, good effect.
The specific embodiment
Below technical scheme of the present invention is clearly and completely described, obviously, described embodiment is only the present invention's part embodiment, rather than whole embodiment.Embodiment based in the present invention, those of ordinary skills, not making under the creative work prerequisite the every other embodiment obtained, belong to the scope of protection of the invention.
Compatibility of drugs of the present invention is reasonable, and its compatibility principle is:
Rhizoma Gastrodiae: property is flat, sweet in the mouth, returns Liver Channel.There is the endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, the effect of dispelling wind and removing obstruction in the collateral, main component is for containing vanillyl alcohol, vanillin, citric acid, gastrodin, polysaccharide, retinoid material, phlegmatic temperament, and the present invention utilizes gastrodin, Vanillyl alcohol, citric acid, the polysaccharide component in Rhizoma Gastrodiae, can be to diabetics relieving spasm by subduing liver-wind, suppressing the hyperactive liver and subsiding YANG, the meridian dredging, prevent patient's apoplectic hemiplegia, blood stagnancy due to deficiency of QI, numb limbs and tense tendons.
Radix Angelicae Sinensis, sweet in the mouth, suffering, hardship, warm in nature, return liver, spleen, heart channel, have and enrich blood; Invigorate blood circulation, moisturize the effect of laxation.The present invention utilizes performance oil, organic acid, polysaccharide, the aminoacid ingredient in Radix Angelicae Sinensis, weakens the cardiac contractile force of diabetics, diabetics is had to the effect of blood sugar lowering, blood fat reducing, antithrombotic formation and blood vessel dilating.
Radix Rehmanniae Preparata, sweet in the mouth, warm in nature, enter liver, kidney channel, there is the YIN nourishing of enriching blood and the effect of liver-nourishing kidney-boosting.The present invention utilizes rehmannia root oligose, iridoid, the aminoacid ingredient in Radix Rehmanniae Preparata, can blood sugar lowering to diabetics,, blood YIN nourishing, life essence-filling, marrow-benefitting; There is control deaf, quench one's thirst, longue meat, the effect of tonifying five ZANG-organs.
Radix Polygoni Multiflori, bitter in the mouth, sweet; Puckery, slightly warm in nature, return liver, kidney channel, there is clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling, the present invention utilizes anthraquinone analog compound, emodin, the chrysophanol composition in Radix Polygoni Multiflori, can blood sugar lowering for diabetics, blood fat reducing, anti-liver injury, have the effect of enriching blood and replenishing vital essence.
Semen Cassiae, sweet in the mouth, bitter, salty, cold nature, return liver, large intestine channel, and the present invention utilizes Semen Cassiae element, the anthraquinone component in Semen Cassiae, and diabetics is had to liver heat removing and eyesight improving, blood pressure lowering, blood fat reducing, cholesterol reducing effect.
Radix Ophiopogonis, property is flat, and sweet in the mouth, micro-acid, return spleen, lung meridian, has nourishing the blood and yin; The effect of loosening bowel to relieve constipation, for deficiency of the spleen and lung, the cardiopalmus of breathing hard symptom, the present invention utilizes saponin, Radix Ophiopogonis polysaccharide, the performance oil component in Radix Ophiopogonis, to diabetics blood sugar lowering, nourishing YIN and moistening the lung, reinforcing stomach reg fluid, contributes to anti-infarction; And elimination free radical.
The Rhizoma Atractylodis Macrocephalae, the sweet in the mouth suffering, temperature, can rise and can fall, and Yang Zhongyin is also, nontoxic.Enter the heart, spleen, stomach, kidney, tri-jiao channel, there is dehumidifying and help digestion, the QI invigorating reinforcing YIN-essence, the effect of the gas of outstanding sharp waist umbilicus, the present invention utilizes atractylone, the atractylodes lactone composition in the Rhizoma Atractylodis Macrocephalae, to the diabetics invigorating the spleen and benefiting QI, control phlegm retention, diuretic wet, there is blood sugar lowering, anti-liver injury, anticoagulant effect.
Fructus Lycii, sweet in the mouth, flat, there is nourishing the liver, nourishing kidney, the effect of lung moistening, Fructus Lycii is classified as " medicine-food two-purpose " kind by Ministry of Public Health, be used to be processed into various food, beverage, health promoting wine, health product etc. more, and the present invention utilizes betanin, aminoacid, the polysaccharide component in Fructus Lycii, to diabetics can invigorating the liver and kidney, benefiting essence-blood, there is improving eyesight, blood sugar lowering, the raising cell tissue effect to the utilization rate of glucose.
Radix Salviae Miltiorrhizae, sweet in the mouth, warm in nature, nontoxic, enter the heart, spleen, lung three warps, the present invention utilizes TANSHINONES, danshensu, catechol, saivianic acid A (first, second, the third) effective ingredient in Radix Salviae Miltiorrhizae, to diabetics blood circulation promoting and blood stasis dispelling, clearing away heart-fire for tranquillization, can play antithrombotic, blood fat reducing, the microcirculatory effect of improvement.
Radix Polygalae, bitter in the mouth, suffering, slightly warm in nature, GUIXIN, kidney, lung meridian, main component is saponin, Radix Polygalae alkali, resin, Radix Polygalae ketone etc., and the present invention utilizes the compositions such as the saponin, Radix Polygalae alkali, resin, Radix Polygalae ketone of Radix Polygalae, the function that diabetics is coagulated heart and tranquilizing mind, goes expectorant to have one's ideas straightened out.
Rhizoma Polygonati, sweet in the mouth, property is flat, returns spleen, lung, kidney channel, has boosting qi and nourishing yin, spleen invigorating, lung moistening, the kidney tonifying effect, the present invention utilizes the main components such as saponin in Rhizoma Polygonati, polysaccharide, alkanol glycosides, and diabetics is played to YIN nourishing benefit essence, invigorating the spleen and replenishing QI, the effect such as quench one's thirst.
According to the component analysis of above-mentioned component, the open following examples of the present invention.
Embodiment 1:
Get: Rhizoma Gastrodiae 50 grams; Radix Angelicae Sinensis 180 grams; Radix Rehmanniae Preparata 120 grams; Radix Polygoni Multiflori 50 grams; Semen Cassiae 150 grams; Radix Ophiopogonis 50 gram; The Rhizoma Atractylodis Macrocephalae 50 grams; Fructus Lycii 250 grams; Radix Salviae Miltiorrhizae 50 grams, Radix Polygalae 100 grams, Rhizoma Polygonati 150 grams, insert described component in pure grain wine 3000 grams of 52 degree, and room temperature sealing is placed 45 days.
Embodiment 2:
Get: Rhizoma Gastrodiae 80 grams; Radix Angelicae Sinensis 100 grams; Radix Rehmanniae Preparata 30 grams; Radix Polygoni Multiflori 30 grams; Semen Cassiae 200 grams; Radix Ophiopogonis 100 gram; The Rhizoma Atractylodis Macrocephalae 100 grams; Fructus Lycii 150 grams; Radix Salviae Miltiorrhizae 100 grams, Radix Polygalae 50 grams, Rhizoma Polygonati 100 grams, insert described component in pure grain wine 6000 grams of 45 degree, and room temperature sealing is placed 50 days.
Embodiment 3:
Get: Rhizoma Gastrodiae 200 grams; Radix Angelicae Sinensis 250 grams; Radix Rehmanniae Preparata 100 grams; Radix Polygoni Multiflori 150 grams; Semen Cassiae 100 grams; Radix Ophiopogonis 100 gram; The Rhizoma Atractylodis Macrocephalae 50 grams; Fructus Lycii 250 grams; Radix Salviae Miltiorrhizae 50 grams, Radix Polygalae 150 grams, Rhizoma Polygonati 180 grams, insert described component in pure grain wine 5000 grams of 60 degree, and room temperature sealing is placed 30 days.
In embodiment, described room temperature sealing is relevant to the number of degrees of composition weight and wine standing time, and the number of degrees of wine are higher, and composition weight is more, and the time that seals can suitably shorten 5-10 days, but had better not, lower than 30 days, guarantee abundant molten the releasing of drug component.
For showing effect of the present invention, the present invention is through clinical observation, and result is as follows:
One, data and method
1, physical data
More than 300, in diabetics, the male accounts for 68%, and the women accounts for 32%; 60%, 40~59 years old account for that account for of 15~20 years old accounted for 19% more than 21%, 60 years old.
2, take effect and method
The medicated wine of the oral embodiment of the present invention 1: after dinner every day 20-30 milliliters; Within 30 days, be a course for the treatment of, the maximum dose of every meal is no more than 100 milliliters, takes 3 courses for the treatment of.
3, observational technique
Observe once weekly during taking, comprise symptom, sign improvement situation, untoward reaction.
4, result
Diabetics is taken 3 courses for the treatment of, and blood glucose is by the near 6.4mmcl/L of 9.8mmcl/L before the meal, and 2 hours blood glucose values are by the near 8.7mmcl/L of 12.2mmcl/L after the meal.Daytime brightlessness in the daytime; weak; sleepy transference cure, the sleep in night recovers normal, can reach 6 to 8 hours the length of one's sleep; numbness of hands and feet, flank pain, the transference cure of pruritus from head to foot; the effect that adopts as can be seen here the molten Chinese medicine of wine is the several times of other pharmaceutical methods, and toxic and side effects is little, and blood sugar lowering is lasting; can fundamentally strengthen the ability of complex functionality and the opposing glycolipid toxin of cell, the protection islet cells increases the B cell quantity.
Through taking of 3 courses for the treatment of, the symptom of diabetics all makes moderate progress, and effective percentage reaches 100%, and the improvement situation refers to table
Sample (people) |
Produce effects (people) |
Invalid (people) |
Effectively (people) |
Effective percentage |
Man 36 |
1 |
1 |
34 |
94% |
The female 30 |
1 |
1 |
28 |
94% |
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited to this, anyly is familiar with those skilled in the art in the technical scope that the present invention discloses; can expect easily changing or replacing, within all should being encompassed in protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion by the described protection domain with claim.