Background technology
The sickness rate of current China diabetes up to 9.7%, number of patients about 9,700 ten thousand people, at present also with every day 3,000 example speed increase., according to World Health Organization's statistics display, the annual Diabetes Death number in the world is seven million peoples, and on average every ten seconds are with regard to a dead example, just have a diabetics every 30 seconds by amputation.The current ill total number of persons of China surmounts the U.S., and India becomes the first in the world.The method that diabetes not there is no radical cure as worldwide difficult medical problem so far because its pathogenesis is very complicated, especially complication, hard to guard against especially, fatality rate, the height of disability rate ranks front three.Show according to up-to-date diabetes study, the pathogenesis traditional Chinese medical science of diabetes is thought to be caused by human body deficiency of both QI and YIN from the Elevation Analysis of strategy, should be caused by the deficiency of vital energy more precisely, the deficiency of vital energy is only had just to match with " The Yellow Emperor's Canon of Internal Medicine " the five internal organs pathogenesis, according to " Huang di's Canon of Medicine ", " TCM basis theory ", " Chinese materia medica ", " Compendium of Materia Medica ", " diabetology " and other scientific theories are for instructing, in fact the traditional Chinese medical science has superiority in diabetes control, health therapy for diabetes and complication thereof can be solved by dietetic therapy, namely by studying on pure book on Chinese herbal medicine, collection food, health product, medicine integration, improve the prevention of Chinese medicine, health care, therapeutic effect.
According to diabetology research display, show have 54 kinds of Chinese herbal medicine to have hypoglycemic activity through zoopery, the Chinese medicine ending the treatment diabetes that in December, 2007 state food drug surveilance office examination & approval are promulgated amounts to 35 kinds, relate to pill, capsule, oral liquid, granule, tablet, injection 6 kinds of dosage forms, wherein only a kind of is the effective ingredient extracted from Chinese medicine.
Show according to up-to-date diabetology research, the Chinese medicinal plant composition with hypoglycemic activity mainly contains: terpenoid, insulin, peptide and amino acids, flavonoid, polysaccharide, thioether class, alkaloids, Coumarins and unsaturated fatty acids etc., they play curative effect by the approach do not allowed and target spot in the treatment of diabetes, but these effective chemicals, the destroyed goods of major part is inactivated under the high temperature conditions, get when in the high quality liquor at 50---53 degree ethanol content, room temperature is molten, the activity of these materials and concentration are then quite high, its hypoglycemic effect is poor unlike Western medicine, and toxic and side effects is little, and there is the effect effected a permanent cure.
Summary of the invention
According to above-mentioned elaboration, the object of the present invention is to provide to play diabetics and regulate equilibrium between yin and yang and a kind for the treatment of and the medicated wine of health-care effect with auxiliary hyperglycemic effect.
A kind of technical scheme to the medicative healthy medicated wine of diabetes tool provided by the invention, has following component at the wine of 3000 grams ~ 30000 grams:
50 grams ~ 200 grams, Rhizoma Gastrodiae; Radix Angelicae Sinensis 100 grams ~ 200 grams; Radix Rehmanniae Preparata 30 grams ~ 150 grams; Radix Polygoni Multiflori 30 grams ~ 150 grams; Semen Cassiae 50 grams ~ 200 grams; Radix Ophiopogonis 30 grams ~ 100 grams; The Rhizoma Atractylodis Macrocephalae 30 grams ~ 100 grams; Fructus Lycii 150 grams ~ 300 grams; Radix Salviae Miltiorrhizae 30 grams ~ 100 grams, Radix Polygalae 50 grams ~ 200 grams, Rhizoma Polygonati 100 grams ~ 200 grams.
In the preferred version of such scheme, there is following component at the wine of 3000 grams ~ 30000 grams:
80 grams ~ 150 grams, Rhizoma Gastrodiae; Radix Angelicae Sinensis 120 grams ~ 180 grams; Radix Rehmanniae Preparata 50 grams ~ 120 grams; Radix Polygoni Multiflori 50 grams ~ 100 grams; Semen Cassiae 100 grams ~ 180 grams; Radix Ophiopogonis 40 grams ~ 80 grams; The Rhizoma Atractylodis Macrocephalae 40 grams ~ 70 grams; Fructus Lycii 180 grams ~ 280 grams; Radix Salviae Miltiorrhizae 40 grams ~ 70 grams, Radix Polygalae 80 grams ~ 150 grams, Rhizoma Polygonati 120 grams ~ 180 grams.
In the preferred version of such scheme, there is following component at the wine of 3000 grams ~ 30000 grams:
90 grams ~ 120 grams, Rhizoma Gastrodiae; Radix Angelicae Sinensis 140 grams ~ 150 grams; Radix Rehmanniae Preparata 80 grams ~ 100 grams; Radix Polygoni Multiflori 50 grams ~ 80 grams; Semen Cassiae 130 grams ~ 150 grams; Radix Ophiopogonis 50 grams ~ 60 grams; The Rhizoma Atractylodis Macrocephalae 50 grams ~ 60 grams; Fructus Lycii 240 grams ~ 250 grams; Radix Salviae Miltiorrhizae 50 grams ~ 60 grams, Radix Polygalae 90 grams ~ 120 grams, Rhizoma Polygonati 150 grams ~ 170 grams.
Described wine is the pure grain wine of 40 ~ 60 degree, as one of in corn wine, Sorghum vulgare Pers. Wine, buckwheat wine, little ale, barley broo.
Preparation method to the medicative healthy medicated wine of diabetes tool provided by the invention is:
Described component inserted in the pure grain wine of 40 ~ 60 degree, room temperature sealing is placed 30-50 days.
The present invention utilizes soaking in Chinese liquor Chinese medicine, reach collection food, health product, the effect of medicine integration, Chinese medicine is passed through soaking in Chinese liquor, utilize the permeability that ethanol is superpower, residence medicine is in wine, wine helps the property of medicine, greatly improve the practicality of Chinese medicine, dissolve a herbal nature difficult problem slowly, give full play to the guiding drug function of wine, strengthen targeting, nutrient substance abundant in wild Chinese herbal medicine is separated out, collection edible wine, health promoting wine, treatment wine is in one, the pharmacy mode of the traditional Chinese medical science is constantly developed, this medicated wine is based on oral, this medicated wine manufacture method is simple, raw material is easy to get, and cost is low, multiple functional, good effect.
Detailed description of the invention
Be clearly and completely described technical scheme of the present invention below, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Compatibility of drugs of the present invention is reasonable, and its compatibility principle is:
Rhizoma Gastrodiae: property is flat, sweet in the mouth, returns Liver Channel.There is endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, effect of dispelling wind and removing obstruction in the collateral, main component is for containing vanillyl alcohol, vanillin, citric acid, gastrodin, polysaccharide, retinoid material, phlegmatic temperament, and the present invention utilizes gastrodin, Vanillyl alcohol, citric acid, polysaccharide component in Rhizoma Gastrodiae, can to diabetics relieving spasm by subduing liver-wind, suppressing the hyperactive liver and subsiding YANG, the meridian dredging, prevent patient's apoplectic hemiplegia, blood stagnancy due to deficiency of QI, numb limbs and tense tendons.
Radix Angelicae Sinensis, sweet in the mouth, pungent, bitter, warm in nature, return liver, spleen, heart channel, have and enrich blood; Invigorate blood circulation, moisturize effect of laxation.The present invention utilizes performance oil, organic acid, polysaccharide, aminoacid ingredient in Radix Angelicae Sinensis, weakens the cardiac contractile force of diabetics, diabetics is had to the effect of blood sugar lowering, blood fat reducing, antithrombus formation and blood vessel dilating.
Radix Rehmanniae Preparata, sweet in the mouth, warm in nature, enter liver, kidney channel, there is effect of enrich blood YIN nourishing and liver-nourishing kidney-boosting.The present invention utilizes rehmannia root oligose, iridoid, aminoacid ingredient in Radix Rehmanniae Preparata, can blood sugar lowering to diabetics, blood YIN nourishing, life essence-filling, marrow-benefitting; There is control deaf, quench one's thirst, longue meat, the effect of tonifying five ZANG-organs.
Radix Polygoni Multiflori, bitter in the mouth, sweet; Puckery, slightly warm in nature, returns liver, kidney channel, have clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling, the present invention utilizes anthraquinone analog compound, emodin, chrysophanol composition in Radix Polygoni Multiflori, can blood sugar lowering for diabetics, blood fat reducing, anti-liver injury, has the effect of enriching blood and replenishing vital essence.
Semen Cassiae, sweet in the mouth, bitter, salty, cold nature, returns liver, large intestine channel, and the present invention utilizes Semen Cassiae element, anthraquinone component in Semen Cassiae, has liver heat removing and eyesight improving, blood pressure lowering, blood fat reducing, cholesterol reducing effect to diabetics.
Radix Ophiopogonis, property is put down, and sweet in the mouth, micro-acid, return spleen, lung meridian, have nourishing the blood and yin; Effect of loosening bowel to relieve constipation, for deficiency of the spleen and lung, cardiopalmus of breathing hard symptom, the present invention utilizes saponin, Radix Ophiopogonis polysaccharide, performance oil component in Radix Ophiopogonis, to diabetics blood sugar lowering, nourishing YIN and moistening the lung, reinforcing stomach reg fluid, contributes to anti-infarction; And elimination free radical.
The Rhizoma Atractylodis Macrocephalae, sweet in the mouth is pungent, temperature, can rise and can fall, and Yang Zhongyin is also, nontoxic.Enter the heart, spleen, stomach, kidney, tri-jiao channel, there is dehumidifying and help digestion, QI invigorating reinforcing YIN-essence, effect of the gas of outstanding sharp waist umbilicus, the present invention utilizes atractylone, atractylodes lactone composition in the Rhizoma Atractylodis Macrocephalae, to diabetics invigorating the spleen and benefiting QI, control phlegm retention, diuretic wets, there is blood sugar lowering, anti-liver injury, anticoagulant effect.
Fructus Lycii, sweet in the mouth, flat, there is nourishing the liver, nourishing kidney, effect of lung moistening, Fructus Lycii is classified as " medicine-food two-purpose " kind by Ministry of Public Health, and be used to be processed into various food, beverage, health promoting wine, health product etc., the present invention utilizes betanin, aminoacid, polysaccharide component in Fructus Lycii more, to diabetics can invigorating the liver and kidney, benefiting essence-blood, there is improving eyesight, blood sugar lowering, raising cell tissue to effect of the utilization rate of glucose.
Radix Salviae Miltiorrhizae, sweet in the mouth, warm in nature, nontoxic, enter the heart, spleen, lung three warp, the present invention utilizes TANSHINONES, danshensu, catechol, saivianic acid A (first, second, third) effective ingredient in Radix Salviae Miltiorrhizae, can play antithrombotic, blood fat reducing, the microcirculatory effect of improvement to diabetics blood circulation promoting and blood stasis dispelling, clearing away heart-fire for tranquillization.
Radix Polygalae, bitter in the mouth, pungent, slightly warm in nature, GUIXIN, kidney, lung meridian, main component is saponin, Radix Polygalae alkali, resin, Radix Polygalae ketone etc., and the present invention utilizes the composition such as saponin, Radix Polygalae alkali, resin, Radix Polygalae ketone of Radix Polygalae, the function of carrying out solidifying heart and tranquilizing mind to diabetics, going expectorant to have one's ideas straightened out.
Rhizoma Polygonati, sweet in the mouth, property is put down, and return spleen, lung, kidney channel, have boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying effect, the present invention utilizes the main component such as saponin, polysaccharide, alkanol glycosides in Rhizoma Polygonati, plays YIN nourishing benefit essence, invigorating the spleen and replenishing QI, the effect such as to quench one's thirst to diabetics.
According to the component analysis of above-mentioned component, the open following examples of the present invention.
Embodiment 1:
Get: 50 grams, Rhizoma Gastrodiae; Radix Angelicae Sinensis 180 grams; Radix Rehmanniae Preparata 120 grams; Radix Polygoni Multiflori 50 grams; Semen Cassiae 150 grams; Radix Ophiopogonis 50 grams; The Rhizoma Atractylodis Macrocephalae 50 grams; Fructus Lycii 250 grams; Radix Salviae Miltiorrhizae 50 grams, Radix Polygalae 100 grams, Rhizoma Polygonati 150 grams, inserts in the pure grain wine 3000 grams of 52 degree by described component, room temperature sealing placement 45 days.
Embodiment 2:
Get: 80 grams, Rhizoma Gastrodiae; Radix Angelicae Sinensis 100 grams; Radix Rehmanniae Preparata 30 grams; Radix Polygoni Multiflori 30 grams; Semen Cassiae 200 grams; Radix Ophiopogonis 100 grams; The Rhizoma Atractylodis Macrocephalae 100 grams; Fructus Lycii 150 grams; Radix Salviae Miltiorrhizae 100 grams, Radix Polygalae 50 grams, Rhizoma Polygonati 100 grams, inserts in the pure grain wine 6000 grams of 45 degree by described component, room temperature sealing placement 50 days.
Embodiment 3:
Get: 200 grams, Rhizoma Gastrodiae; Radix Angelicae Sinensis 250 grams; Radix Rehmanniae Preparata 100 grams; Radix Polygoni Multiflori 150 grams; Semen Cassiae 100 grams; Radix Ophiopogonis 100 grams; The Rhizoma Atractylodis Macrocephalae 50 grams; Fructus Lycii 250 grams; Radix Salviae Miltiorrhizae 50 grams, Radix Polygalae 150 grams, Rhizoma Polygonati 180 grams, inserts in the pure grain wine 5000 grams of 60 degree by described component, room temperature sealing placement 30 days.
In embodiment, described room temperature sealing is relevant to the number of degrees of composition weight and wine for standing time, and the number of degrees of wine are higher, and composition weight is more, then Sealing period suitably can shorten 5-10 days, but lower than 30 days, had better not ensure that the fully molten of drug component is released.
For showing effect of the present invention, the present invention is through clinical observation, and result is as follows:
One, data and method
1, physical data
In more than 300 diabeticss, male accounts for 68%, and women accounts for 32%; 15 ~ 20 years old account for 60%, 40 ~ 59 years old account for more than 21%, 60 years old account for 19%.
2, effect and method is taken
The medicated wine of the oral embodiment of the present invention 1: after dinner every day 20-30 milliliters; Within 30 days, be a course for the treatment of, maximum dose of often eating is no more than 100 milliliters, takes 3 courses for the treatment of.
3, observational technique
Take period to observe weekly once, comprise symptom, sign improves situation, untoward reaction.
4, result
Diabetics takes 3 courses for the treatment of, and preprandial glucose is by the near 6.4mmcl/L of 9.8mmcl/L, and 2 hours blood glucose values are by the near 8.7mmcl/L of 12.2mmcl/L after the meal.Daytime brightlessness in the daytime; weak; sleepy transference cure, night sleep recovers normal, and the length of one's sleep can reach 6 to 8 hours; the transference cure of numbness of hands and feet, flank pain, from head to foot pruritus; the effect of the molten Chinese medicine of employing wine is the several times of other pharmaceutical methods as can be seen here, and toxic and side effects is little, and blood sugar lowering is lasting; fundamentally can strengthen the complex functionality of cell and the ability of opposing glycolipid toxin, protection islet cells increases B cell quantity.
Through taking of 3 courses for the treatment of, the symptom of diabetics all makes moderate progress, and effective percentage reaches 100%, and improvement situation refers to table
Sample (people) |
Effective (people) |
Invalid (people) |
Effectively (people) |
Effective percentage |
Man 36 |
1 |
1 |
34 |
94% |
Female 30 |
1 |
1 |
28 |
94% |
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; change can be expected easily or replace, all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should described be as the criterion with the protection domain of claim.