A kind of for Chinese medicinal effective-part composition removing the dandruff and preparation method thereof
Technical field
The present invention relates to Chinese medicine composition field, be specifically related to a kind of for Chinese medicinal effective-part composition removing the dandruff and preparation method thereof.
Background technology
The dandruff is medically called capitis pityriasis, is a kind of dermatosis caused by chlosma (one in fungus).The amount reproduction of chlosma on scalp causes the cuticular hyperplasia of scalp, thus impels corneocyte extremely to come off with the form of white or Lycoperdon polymorphum Vitt squama, and this squama come off is the dandruff.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicinal effective-part composition for the preparation of removing the dandruff, this Chinese medicinal effective-part composition can remove the dandruff fast and effectively, has the advantage that therapeutic effect is remarkable, safety is high, have no side effect, not easily recur.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The Chinese medicinal effective-part composition of the removal dandruff of the present invention is made up of the following raw material according to mass fraction meter: thin,tough silk hair chrysanthemum 26, Moschus 22, Fructus Amomi Rotundus 19, Rhizoma Acori Calami 15 and Punica granatum L. 18.
The dosage form that the Chinese medicinal effective-part composition that the present invention removes the dandruff is applicable to processing is external-use lotion.
The preparation method of the Chinese medicinal effective-part composition of the removal dandruff of the present invention is that add 15 times of water gagings, decoct 3.5 hours, waste, to obtain final product by each compositions according to proportioning combination drying.
Compared with prior art, the present invention has following beneficial effect:
(1) compositions of the present invention can remove the dandruff fast and effectively, particularly the intractable dandruff, once curing, not easily recurs.
(2) present composition has no side effect.
(3) preparation method of the present composition is simple, and yield is high, effectively maintains the effective ingredient of medicine.
Detailed description of the invention
Explain the present invention further below in conjunction with embodiment, but embodiment does not limit in any form to the present invention.
embodiment 1
Get thin,tough silk hair chrysanthemum 26g, Moschus 22g, Fructus Amomi Rotundus 19g, Rhizoma Acori Calami 15g and Punica granatum L. 18g, be crushed to coarse powder, add 15 times of water gagings, decoct 3.5 hours, obtain external-use lotion.
embodiment 2
Clinical observation patient 300 example, patient all has obvious capitis pityriasis clinical symptoms and makes a definite diagnosis through clinicist.
The external-use lotion that patient uses embodiment 1 obtained, once a day, at every turn with appropriate cleaning head dermatome portion, uses two weeks continuously.
The patient census of embodiment 1 gained external-use lotion is used to the results are shown in Table 1.
Criterion of therapeutical effect: effectively comprise two grades.One-level is silvery white squama disappearance on scalp after treatment, and scalp is not itched, and produces, do not recur in 1 year without dandruff; Also there is minute quantity for treating silvery white squama on scalp in secondary, but scalp is not itched, and do not turn around bits yet, do not recur in 1 year.Invalid refer to treatment after, symptom and sign fail to improve, and even increase the weight of.
Table 1
Number of cases |
Effective |
Invalid |
Obvious effective rate (%) |
300 |
288 |
12 |
96 |
Known by table 1, the external-use lotion that embodiment 1 obtains has specially good effect in treatment capitis pityriasis (dandruff).Following up a case by regular visits to through follow-up, all there is not the symptom recurred in the effective patient of above-mentioned drug administration.
embodiment 3
Use the external-use lotion administration ICR mice that embodiment 1 is obtained, body weight 20 ~ 25g, male and female half and half, successive administration 90d.
Through prerun, the lotion toxicity that embodiment 1 obtains is very low, does not measure LD50, therefore carries out maximum dosage-feeding mensuration on the one to mice.Maximum dosage-feeding is 100ml/d, observes none example and be poisoned to death after 90 days, and all healthy survival, proves that the external-use lotion that compositions of the present invention is made can not cause toxic and side effects to human body thus.