A kind of for removing Chinese medicinal effective-part composition of the dandruff and preparation method thereof
Technical field
The present invention relates to the Chinese medicine composition field, be specifically related to a kind of for removing Chinese medicinal effective-part composition of the dandruff and preparation method thereof.
Background technology
The dandruff medically is being called capitis pityriasis, is a kind of dermatosis caused by chlosma (in fungus a kind of).The amount reproduction of chlosma on scalp causes the cuticular hyperplasia of scalp, thereby impels corneocyte extremely to come off with the form of white or Lycoperdon polymorphum Vitt squama, and this squama come off is the dandruff.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicinal effective-part composition for the preparation of removing the dandruff, this Chinese medicinal effective-part composition can be removed the dandruff fast and effectively, has advantages of that therapeutic effect is remarkable, safe, has no side effect, is difficult for recurrence.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The Chinese medicinal effective-part composition of the removal dandruff of the present invention is by making according to the raw material of mass fraction meter as follows: thin,tough silk hair chrysanthemum 26, Moschus 22, Fructus Amomi Rotundus 19, Rhizoma Acori Calami 15 and Punica granatum L. 18.
The dosage form that the present invention removes the applicable processing of Chinese medicinal effective-part composition of the dandruff is external-use lotion.
The preparation method of the Chinese medicinal effective-part composition of the removal dandruff of the present invention be by each compositions according to the proportioning combination drying, add 15 times of water gagings, decoct 3.5 hours, waste, obtain.
Compared with prior art, the present invention has following beneficial effect:
(1) compositions of the present invention can be removed the dandruff, particularly the intractable dandruff fast and effectively, once curing, is difficult for recurrence.
(2) present composition has no side effect.
(3) preparation method of the present composition is simple, and yield is high, has effectively kept the effective ingredient of medicine.
The specific embodiment
Further explain the present invention below in conjunction with embodiment, but embodiment does not limit in any form to the present invention.
embodiment 1
Get thin,tough silk hair chrysanthemum 26g, Moschus 22g, Fructus Amomi Rotundus 19g, Rhizoma Acori Calami 15g and Punica granatum L. 18g, be crushed to coarse powder, add 15 times of water gagings, decoct 3.5 hours, obtain external-use lotion.
embodiment 2
Clinical observation patient 300 examples, patient all has obvious capitis pityriasis clinical symptoms and makes a definite diagnosis through the clinicist.
The external-use lotion that the patient uses embodiment 1 to make once a day, is used appropriate cleaning head dermatome section at every turn, uses continuously two weeks.
Use patient's statistical result of embodiment 1 gained external-use lotion in Table 1.
Criterion of therapeutical effect: produce effects comprises two grades.One-level disappears for silvery white squama on the rear scalp for the treatment of, and scalp is not itched, and without dandruff, produces, and in 1 year, does not recur; Also there is minute quantity in secondary for silvery white squama on the treatment scalp, but scalp do not itch, and the bits that yet do not turn around, do not recur in 1 year.Invalid refer to treatment after, symptom and sign fail to improve, and even increase the weight of.
Table 1
Number of cases |
Produce effects |
Invalid |
Obvious effective rate (%) |
300 |
288 |
12 |
96 |
Known by table 1, the external-use lotion that embodiment 1 obtains has specially good effect at treatment capitis pityriasis (dandruff).Through follow-up following up a case by regular visits to, the symptom of recurrence does not all appear in the patient of above-mentioned drug administration produce effects.
embodiment 3
The external-use lotion administration ICR mice of using embodiment 1 to make, body weight 20 ~ 25g, male and female half and half, successive administration 90d.
Through prerun, the lotion toxicity that embodiment 1 makes is very low, does not measure LD50, therefore mice is carried out to maximum dosage-feeding on the one, measures.Maximum dosage-feeding is 100ml/d, observes none example after 90 days and is poisoned to death, and all healthy survival, prove that the external-use lotion that compositions of the present invention is made can not cause toxic and side effects to human body thus.