CN103239543B - Chinese medicine effective part composition for treating gastroptosis and preparation method of Chinese medicine effective part composition - Google Patents

Chinese medicine effective part composition for treating gastroptosis and preparation method of Chinese medicine effective part composition Download PDF

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Publication number
CN103239543B
CN103239543B CN201310197803.6A CN201310197803A CN103239543B CN 103239543 B CN103239543 B CN 103239543B CN 201310197803 A CN201310197803 A CN 201310197803A CN 103239543 B CN103239543 B CN 103239543B
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China
Prior art keywords
part composition
gastroptosis
chinese medicinal
chinese medicine
effective part
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Expired - Fee Related
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CN201310197803.6A
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Chinese (zh)
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CN103239543A (en
Inventor
张群
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GUANGZHOU YUNQIAO BIOLOGICAL TECHNOLOGY Co Ltd
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GUANGZHOU YUNQIAO BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

The invention discloses a Chinese medicine effective part composition for treating gastroptosis. The Chinese medicine effective part composition is prepared from the following raw materials in parts by weight: radix angelicae pubescentis, fructus evodiae, eucommia ulmoides, golden cypress and smoked plum. The Chinese medicine effective part composition can be prepared into medicines for treating the gastroptosis, has the effects of tonifying spleen, invigorating stomach, tonifying qi-rise and nourishing stomach-yin, can be used for remarkably treating the gastroptosis and has the advantages of no toxic or side effects and high safety.

Description

A kind of Chinese medicinal effective-part composition that is used for the treatment of gastroptosis and preparation method thereof
Technical field
The present invention relates to Chinese medicine composition field, be specifically related to a kind of Chinese medicinal effective-part composition that is used for the treatment of gastroptosis and preparation method thereof.
Background technology
Gastroptosis refers to that with lesser gastric curvature angular incisure, lower than below interiliac line, pyloric cap is offset a kind of disease into main physical signs left.With 30~50 years old common, women is more than male.Modern western medicine, except symptomatic treatment, there is no specific short.
At present, the cause of disease of gastroptosis divides nature and nurture two classes.Congenital factors is natural endowment weakness, body constitution virtual loss; Can be summarized as drinking and eating irregularly the day after tomorrow, and prolonged illness or delivery and feed infant are too much, and seven emotions are indisposed etc.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicinal effective-part composition for the preparation for the treatment of gastroptosis, this Chinese medicinal effective-part composition can be treated gastroptosis fast and effectively, has advantages of that therapeutic effect is remarkable, safe, has no side effect.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The Chinese medicinal effective-part composition for the treatment of gastroptosis of the present invention is by making according to the raw material of mass fraction meter as follows: Radix Angelicae Pubescentis 12, Fructus Evodiae 30, the Cortex Eucommiae 27, Cortex Phellodendri 22 and Fructus Mume 9.
The dosage form that the present invention treats the applicable processing of Chinese medicinal effective-part composition of gastroptosis is tablet, oral liquid or capsule.
The preparation method of the Chinese medicinal effective-part composition for the treatment of gastroptosis of the present invention comprises the steps:
(1) each Chinese medicinal components is pulverized, added 10 times of water gagings, decoct 3 times, decoct 1.5 hours at every turn; Filter merging filtrate after decocting liquid, be evaporated to relative concentration and be 1.18 cream, add ethanol, making it contain alcohol amount is 66%, and hold over night reclaims ethanol, concentrated;
(2) concentrated solution after concentrated is added to applicable adjuvant according to conventional formulation technique, be processed into corresponding dosage form.
Compared with prior art, the present invention has following beneficial effect:
(1) compositions of the present invention has spleen reinforcing stomach invigorating, QI invigorating rises the effect that falls into, moistens nourishing stomach-YIN, through test, and can fast treating gastroptosis.
(2) present composition has no side effect.
(3) preparation method of the present composition is simple, and yield is high, has effectively kept the effective ingredient of medicine.
The specific embodiment
Below in conjunction with embodiment, further explain the present invention, but embodiment does not limit in any form to the present invention.
embodiment 1
Get Radix Angelicae Pubescentis 12g, Fructus Evodiae 30g, Cortex Eucommiae 27g, Cortex Phellodendri 22g and Fructus Mume 9g, be crushed to coarse powder, add 10 times of water gagings, decoct 3 times, decoct 1.5 hours at every turn; Filter merging filtrate after decocting liquid, be evaporated to relative concentration and be 1.18 cream, add ethanol, making it contain alcohol amount is 66%, and hold over night reclaims ethanol, obtain concentrated solution 1000ml, get simple syrup, add above-mentioned concentrated solution, and with citric acid adjust pH to 4, adding distil water is to 5000ml, stir, after fine straining, be distributed in 15ml vial, be packaged to be oral liquid.
This product is brownish black clear liquid, places in half a year and does not produce muddiness, pH approximately 4, total solid 5% left and right.
embodiment 2
Clinical observation patient 300 examples, patient all has obvious gastroptosis clinical symptoms and makes a definite diagnosis through clinicist.
The oral liquid that the oral embodiment 1 of patient makes, every day sooner or later respectively once, each 15ml.
After 15 days, use patient's statistical result of embodiment 1 gained oral liquid in Table 1.Criterion of therapeutical effect: effective is clinical symptom disappearance or obviously alleviate, X-ray check, under stomach, the utmost point gos up to 4 centimetres of normal positions even above; Invalid is that symptom is slightly improved or without improvement, sign is without change.
Table 1
Number of cases Effective Invalid Obvious effective rate (%)
300 281 19 93.67
Known by table 1, the oral liquid that embodiment 1 obtains has specially good effect at treatment gastroptosis.Chinese medicine of the present invention is made after oral liquid, can be in 15 days highly significant healing or alleviate gastroptosis disease.
embodiment 3
The oral liquid administration ICR mice of using embodiment 1 to make, body weight 20 ~ 25g, male and female half and half, successive administration 30d.
Through prerun, the lotion toxicity that embodiment 1 makes is very low, does not measure LD50, therefore mice is carried out to maximum dosage-feeding on the one, measures.Maximum dosage-feeding is 100ml/d, observes none example and be poisoned to death after 60 days, and all healthy survival, proves that the oral liquid that compositions of the present invention is made can not cause toxic and side effects to human body thus.

Claims (4)

1. treat a Chinese medicinal effective-part composition for gastroptosis, it is characterized in that by making according to the raw material of mass fraction meter as follows: Radix Angelicae Pubescentis 12, Fructus Evodiae 30, the Cortex Eucommiae 27, Cortex Phellodendri 22 and Fructus Mume 9.
2. the Chinese medicinal effective-part composition for the treatment of gastroptosis according to claim 1, is characterized in that described Chinese medicine composition makes tablet, oral liquid or capsule.
3. the preparation method for the treatment of the Chinese medicinal effective-part composition of gastroptosis described in claim 1 or 2, is characterized in that comprising the steps:
(1) each Chinese medicinal components is pulverized, added 10 times of water gagings, decoct 3 times, decoct 1.5 hours at every turn; Filter merging filtrate after decocting liquid, be evaporated to relative concentration and be 1.18 cream, add ethanol, making it contain alcohol amount is 66%, and hold over night reclaims ethanol, concentrated;
(2) concentrated solution after concentrated is added to applicable adjuvant according to conventional formulation technique, be processed into corresponding dosage form.
4. the application of Chinese medicinal effective-part composition described in claim 1 or 2, is characterized in that the medicine of described Chinese medicinal effective-part composition for the preparation for the treatment of gastroptosis.
CN201310197803.6A 2013-05-25 2013-05-25 Chinese medicine effective part composition for treating gastroptosis and preparation method of Chinese medicine effective part composition Expired - Fee Related CN103239543B (en)

Priority Applications (1)

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CN201310197803.6A CN103239543B (en) 2013-05-25 2013-05-25 Chinese medicine effective part composition for treating gastroptosis and preparation method of Chinese medicine effective part composition

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CN103239543B true CN103239543B (en) 2014-04-30

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105267873A (en) * 2015-11-17 2016-01-27 孙绪连 Traditional Chinese medicine composition for treating gastroptosis

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
乔玉山.综合治疗胃下垂85例.《湖南中医杂志》.2005,第21卷(第04期),第38-39页.
综合治疗胃下垂85例;乔玉山;《湖南中医杂志》;20051231;第21卷(第04期);第38-39页 *
辨证论治胃下垂32例;陆朝魁;《疑难病杂志》;20031231;第2卷(第03期);第166-167页 *
陆朝魁.辨证论治胃下垂32例.《疑难病杂志》.2003,第2卷(第03期),第166-167页.

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