Summary of the invention
The invention provides a kind of Chinese medicine preparation for nursing poliomyelitis sequela and preparation method, selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet the traditional Chinese medical science and modern medicine theory, there is tonifying speen and tonifying kidney, effect of the dissipating blood stasis that dispels the wind, relaxing muscles and tendons and activating QI and blood in the collateral, the many sequela such as muscular paralysis, quadriplegia, cacomelia caused for poliomyelitis have significant curative effect, safe without toxic side effect, treatment for poliomyelitis sequela has great clinical meaning, and should be widely promoted application.
For achieving the above object, technical scheme of the present invention is implemented as follows:
For nursing a Chinese medicine preparation for poliomyelitis sequela, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 35-60 part Lysimachia trientaloides Hemsl. 30-60 part Radix Pittospori Glabrati 30-50 part Rhizoma Corydalis Decumbentis 30-45 part
Herba Urticae Cannabinae 28-43 part Radix Tylophorae Yunnanensis 26-36 part Folium Evodiae trichotomae 23-35 part Folium Craibiodendri Yunnanensis 20-35 part
Radix seu Caulis Parthenocissi tricuspidatae 20-34 part Rhizoma Gastrodiae 18-30 part Radix Campylotropis Macrocarpae 15-25 part Herba Goodyerae Procerae 15-28 part
Herba lagopsis supinae 10-25 part Scorpio 10-23 part Carapax Eretmochelydis 8-18 part Herba Chrysosplenii Macrophylli 8-22 part.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 50 parts of Lysimachia trientaloides Hemsl.s 45 parts of Radix Pittospori Glabratis 42 parts of Rhizoma Corydalis Decumbentiss 39 parts
Herba Urticae Cannabinae 37 parts of Radix Tylophorae Yunnanensis 32 parts of Folium Evodiae trichotomae 29 parts of Folium Craibiodendri Yunnanensiss 29 parts
Radix seu Caulis Parthenocissi tricuspidatae 29 parts of Rhizoma Gastrodiaes 26 parts of Radix Campylotropis Macrocarpae 21 parts of Herba Goodyerae Proceraes 22 parts
Herba lagopsis supinae 18 portions of Scorpios 16 parts of Carapax Eretmochelydiss 14 parts of Herba Chrysosplenii Macrophyllis 17 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 45 parts of Lysimachia trientaloides Hemsl.s 40 parts of Radix Pittospori Glabratis 38 parts of Rhizoma Corydalis Decumbentiss 36 parts
Herba Urticae Cannabinae 34 parts of Radix Tylophorae Yunnanensis 30 parts of Folium Evodiae trichotomae 27 parts of Folium Craibiodendri Yunnanensiss 26 parts
Radix seu Caulis Parthenocissi tricuspidatae 26 parts of Rhizoma Gastrodiaes 24 parts of Radix Campylotropis Macrocarpae 19 parts of Herba Goodyerae Proceraes 19 parts
Herba lagopsis supinae 15 portions of Scorpios 14 parts of Carapax Eretmochelydiss 12 parts of Herba Chrysosplenii Macrophyllis 14 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 40 parts of Lysimachia trientaloides Hemsl.s 35 parts of Radix Pittospori Glabratis 34 parts of Rhizoma Corydalis Decumbentiss 33 parts
Herba Urticae Cannabinae 31 parts of Radix Tylophorae Yunnanensis 28 parts of Folium Evodiae trichotomae 25 parts of Folium Craibiodendri Yunnanensiss 23 parts
Radix seu Caulis Parthenocissi tricuspidatae 23 parts of Rhizoma Gastrodiaes 21 parts of Radix Campylotropis Macrocarpae 17 parts of Herba Goodyerae Proceraes 17 parts
Herba lagopsis supinae 12 portions of Scorpios 12 parts of Carapax Eretmochelydiss 10 parts of Herba Chrysosplenii Macrophyllis 11 parts.
For nursing a preparation method for the Chinese medicine preparation of poliomyelitis sequela, comprise following processing step:
(1) get Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels), Radix Pittospori Glabrati, Radix seu Caulis Parthenocissi tricuspidatae, Herba Urticae Cannabinae, Folium Evodiae trichotomae, Rhizoma Gastrodiae, Herba lagopsis supinae and Herba Chrysosplenii Macrophylli to clean, dry, put into container, add the distilled water of 8-12 times amount, soak after 4-5 hour, boil 3-4 hour, extract; Again add 6-8 times amount distilled water, boil 2-3 hour, extract; Finally, add 4-6 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, reserved filtrate is for subsequent use;
(2) get Lysimachia trientaloides Hemsl., Radix Tylophorae Yunnanensis, Radix Campylotropis Macrocarpae and Herba Goodyerae Procerae to clean, dry, immerse the alcohol solution dipping 2 ~ 3 hours of 75% of 6 times amount, heating extraction 4 hours, reclaim ethanol, filter, at simmer down to 60 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(3) get Rhizoma Corydalis Decumbentis, Scorpio and Folium Craibiodendri Yunnanensis to dry, be placed in mortar, grind into powder, cross 200 order fine powders, for subsequent use;
(4) get Carapax Eretmochelydis to clean, dry, smash to pieces, mill with stone grinder, cross 120 order fine powders, for subsequent use;
(5) get the filtrate obtained by above-mentioned steps (1)-(4), thick paste and fine powder mixing, utilize modern advanced pharmacy science and technology, making tablet, being the described Chinese medicine preparation for nursing poliomyelitis sequela.
The property of medicine of the present invention's Chinese medicine used is as follows:
Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels): bitter in the mouth, pungent, property is put down, and returns liver, kidney channel.Dispelling wind and removing obstruction in the collateral.Main hemiplegia, poliomyelitis sequela." will planted by middle traditional Chinese medicines " carries: " control Pe1lionia tsoongii (Merr.) Merr..”
Lysimachia trientaloides Hemsl.: acrid in the mouth, warm in nature.Dispelling wind and removing obstruction in the collateral, promoting blood circulation and stopping pain.Cure mainly rheumatic arthralgia, hemiplegia, infantile convulsion, traumatic injury, fracture." Guizhou side's medicine among the people collection " carries: " wind dispelling is calm, dispelling the wind and dampness pathogens pain, hemiplegia.”
Radix Pittospori Glabrati: sweet in the mouth, hardship, cool in nature.Tonifying the lung kidney, wind-damp dispelling, promoting blood circulation to remove obstruction in the collateral.Cure mainly asthenia to breath with cough, seminal emission premature ejaculation, insomnia, dizzy, hypertension, rheumatic arthralgia, infantile paralysis.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " promoting blood circulation to remove obstruction in the collateral, relieving spasm to stop pain.Treating rheumatic arthritis, sciatica, injury and bone fracture, poliomyelitis sequela, puerperal paralysis, heart peratodynia, toothache.”
Rhizoma Corydalis Decumbentis: bitter in the mouth, micro-pungent, warm in nature, returns Liver Channel.Blood pressure lowering spasmolytic, promoting blood circulation to remove obstruction in the collateral, promoting the circulation of QI to relieve pain.For hemiplegia, apoplectic hemiplegia, injury from falling down, rheumatic arthritis, sciatica, poliomyelitis sequela." Zhejiang conventional medical herbs among the people " carries: " promoting the circulation of blood, invigorates blood circulation, hemostasis, pain relieving, spasmolytic.”
Herba Urticae Cannabinae: bitter in the mouth, pungent, warm in nature, poisonous.Dispelling wind and removing obstruction in the collateral, suppressing the hyperactive liver is calmed the frightened, removing food stagnancy relieving constipation, removing toxic substances.Cure mainly rheumatic arthralgia, puerperal convulsion, infantile convulsion, poliomyelitis sequela, hypertension, dyspepsia, constipation, urticaria, traumatic injury, worm venom." discriminating of Heilungkiang Main Wild Medicinal plant and Chinese herbal medicine novel formulation " carries: " control poliomyelitis, rheumatism, colic.”
Radix Tylophorae Yunnanensis: bitter in the mouth, pungent, slightly warm in nature, returns liver, spleen channel.Kuai, a state in the Zhou Dynasty dish dredging collateral, promoting blood circulation and stopping pain.Cure mainly rheumatic ostalgia hepatitis, gastric ulcer, poliomyelitis sequela, traumatic injury.
Folium Evodiae trichotomae: acrid in the mouth, hardship, warm in nature, attach to the lung and stomach meridians.Expelling wind and removing dampness, dispersing cold for relieving pain.Cure mainly poliomyelitis sequela, rheumatic arthritis, eczema, urticaria, skin infection, headche due to wind-cold." choosing of Simao, Yunnan Chinese herbal medicine " carries: " control poliomyelitis sequela, rheumatic arthritis, urticaria, eczema, skin sore is itched.”
Folium Craibiodendri Yunnanensis: pungent, puckery, temperature, poisonous.Eliminating stasis to stop pain, expelling wind and removing dampness, stops blooding sensible.For traumatic injury, traumatic stupor, bruise, lumbago and skelalgia, hemiplegia, paralysis, rheumatic arthritis, traumatic hemorrhage, fracture." Yunnan Chinese herbal medicine " carries: " relieving superficies and warmign meridians, activating collaterals to relieve pain.Control traumatic injury, rheumatic numbness, affection of exogenous wind-cold.”
Radix seu Caulis Parthenocissi tricuspidatae: sweet in the mouth, warm in nature, return Liver Channel.Invigorate blood circulation, Qu Feng, limbs.Cure mainly blood stasis in puerperal, in abdomen, have block, leucorrhea with red and white discharge, rheumatism bones and muscles pain, migraine, rheumatic arthralgia, apoplexy and hemiplegia, migraine and general headache, traumatic injury, carbuncle sore tumefacting virus, ulcer being unable to heal.
Rhizoma Gastrodiae: sweet in the mouth, property is put down, and returns Liver Channel.Endogenous wind stopping, arresting convulsion, relieving convulsion.Cure mainly dizzy pupil, wind syndrome of head is had a headache, numb limbs and tense tendons, hemiplegia, aphasia, pediatric epilepsy scared wind symptom.Suppressing the hyperactive liver to relieve the wind syndrome." book on Chinese herbal medicine converges and says " carries: " dizzy void is revolved, the strong convulsion of epilepsy for main wind syndrome of head, headache, and extremity contraction is anxious, and language has some setbacks, all apoplexy, wind-phlegm.”
Radix Campylotropis Macrocarpae: bitter in the mouth, pungent, property is put down, and returns liver, spleen channel.Dispelling wind to relieve the exterior syndrome, relaxing muscles and tendons to promote blood circulation.Cure mainly numb limbs and tense tendons, hemiplegia.
Herba Goodyerae Procerae: bitter in the mouth, pungent, warm in nature.Expelling wind and removing dampness, tonifying the blood and stretching the tendon.Cure mainly anemofrigid-damp arthralgia, hemiplegia, hemiplegia, paralysis, traumatic injury, cough with asthma, stomachache, edema." Zhiwu Mingshi Tukao " carries: " nourish blood, soothing liver-QI, QI invigorating, nourishing kidney.Enter muscle to dispel the wind, dehumidify to the marrow.”
Herba lagopsis supinae: mildly bitter flavor, property is put down, slightly poisonous.Nourishing blood for regulating menstruation.For anemicus dizziness, hemiplegia, menoxenia.
Scorpio: acrid in the mouth, property is put down, poisonous, returns Liver Channel.Endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula." Shandong Chinese herbal medicine handbook " carries: " endogenous wind stopping dredging collateral, spasmolytic.Control thromboangiitis obliterans, tuberculous lymphadenitis, tuberculosis of bone and joint, mumps.”
Carapax Eretmochelydis: sweet in the mouth, salty, cold in nature, GUIXIN, Liver Channel.Heat clearing away, removing toxic substances, relieving convulsion.Cure mainly calentura mania and irritation, apoplexy, delirium, convulsion is fainted, pediatric epilepsy scared, carbuncle sore tumefacting virus." Japan hanako materia medica " carries: " break and levy knot, eliminating carbuncle poison, spasmolytic epilepsy.”
Herba Chrysosplenii Macrophylli: bitter in the mouth, puckery, cold in nature.Heat-clearing and toxic substances removing, promoting tissue regeneration by astringents." light Rhizoma Dioscoreae plants will in Zhejiang " carries: " control infantile convulsion.”
The present invention compared with prior art, has following beneficial effect:
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet the traditional Chinese medical science and modern medicine theory, there is tonifying speen and tonifying kidney, effect of the dissipating blood stasis that dispels the wind, relaxing muscles and tendons and activating QI and blood in the collateral, the many sequela such as muscular paralysis, quadriplegia, cacomelia caused for poliomyelitis have significant curative effect, safe without toxic side effect, treatment for poliomyelitis sequela has great clinical meaning, and should be widely promoted application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 55g Lysimachia trientaloides Hemsl. 50g Radix Pittospori Glabrati 46g Rhizoma Corydalis Decumbentis 42g
Herba Urticae Cannabinae 40g Radix Tylophorae Yunnanensis 34g Folium Evodiae trichotomae 32g Folium Craibiodendri Yunnanensis 32g
Radix seu Caulis Parthenocissi tricuspidatae 32g Rhizoma Gastrodiae 28g Radix Campylotropis Macrocarpae 23g Herba Goodyerae Procerae 25g
Herba lagopsis supinae 22g Scorpio 18g Carapax Eretmochelydis 16g Herba Chrysosplenii Macrophylli 20g.
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) get Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels), Radix Pittospori Glabrati, Radix seu Caulis Parthenocissi tricuspidatae, Herba Urticae Cannabinae, Folium Evodiae trichotomae, Rhizoma Gastrodiae, Herba lagopsis supinae and Herba Chrysosplenii Macrophylli to clean, dry, put into container, add the distilled water of 8-12 times amount, soak after 4-5 hour, boil 3-4 hour, extract; Again add 6-8 times amount distilled water, boil 2-3 hour, extract; Finally, add 4-6 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, reserved filtrate is for subsequent use;
(2) get Lysimachia trientaloides Hemsl., Radix Tylophorae Yunnanensis, Radix Campylotropis Macrocarpae and Herba Goodyerae Procerae to clean, dry, immerse the alcohol solution dipping 2 ~ 3 hours of 75% of 6 times amount, heating extraction 4 hours, reclaim ethanol, filter, at simmer down to 60 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(3) get Rhizoma Corydalis Decumbentis, Scorpio and Folium Craibiodendri Yunnanensis to dry, be placed in mortar, grind into powder, cross 200 order fine powders, for subsequent use;
(4) get Carapax Eretmochelydis to clean, dry, smash to pieces, mill with stone grinder, cross 120 order fine powders, for subsequent use;
(5) get the filtrate obtained by above-mentioned steps (1)-(4), thick paste and fine powder mixing, utilize modern advanced pharmacy science and technology, making tablet, being the described Chinese medicine preparation for nursing poliomyelitis sequela.
Usage and dosage: oral, every day three times, each 3, within ten days, be a course for the treatment of, six to eight courses for the treatment of can cure, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 50g Lysimachia trientaloides Hemsl. 45g Radix Pittospori Glabrati 42g Rhizoma Corydalis Decumbentis 39g
Herba Urticae Cannabinae 37g Radix Tylophorae Yunnanensis 32g Folium Evodiae trichotomae 29g Folium Craibiodendri Yunnanensis 29g
Radix seu Caulis Parthenocissi tricuspidatae 29g Rhizoma Gastrodiae 26g Radix Campylotropis Macrocarpae 21g Herba Goodyerae Procerae 22g
Herba lagopsis supinae 18g Scorpio 16g Carapax Eretmochelydis 14g Herba Chrysosplenii Macrophylli 17g.
The present embodiment Chinese medicine preparation preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 45g Lysimachia trientaloides Hemsl. 40g Radix Pittospori Glabrati 38g Rhizoma Corydalis Decumbentis 36g
Herba Urticae Cannabinae 34g Radix Tylophorae Yunnanensis 30g Folium Evodiae trichotomae 27g Folium Craibiodendri Yunnanensis 26g
Radix seu Caulis Parthenocissi tricuspidatae 26g Rhizoma Gastrodiae 24g Radix Campylotropis Macrocarpae 19g Herba Goodyerae Procerae 19g
Herba lagopsis supinae 15g Scorpio 14g Carapax Eretmochelydis 12g Herba Chrysosplenii Macrophylli 14g.
The present embodiment Chinese medicine preparation preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 40g Lysimachia trientaloides Hemsl. 35g Radix Pittospori Glabrati 34g Rhizoma Corydalis Decumbentis 33g
Herba Urticae Cannabinae 31g Radix Tylophorae Yunnanensis 28g Folium Evodiae trichotomae 25g Folium Craibiodendri Yunnanensis 23g
Radix seu Caulis Parthenocissi tricuspidatae 23g Rhizoma Gastrodiae 21g Radix Campylotropis Macrocarpae 17g Herba Goodyerae Procerae 17g
Herba lagopsis supinae 12g Scorpio 12g Carapax Eretmochelydis 10g Herba Chrysosplenii Macrophylli 11g.
The present embodiment Chinese medicine preparation preparation method processing step and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for nursing poliomyelitis sequela, select the routine clinical observation of poliomyelitis sequela patient 360, patient is divided into two groups at random, treatment group 180 example, wherein man 92 example, women 88 example, age 2-45 year, 21.3 years old mean age, course of disease 1-10, average 5.2 years; Matched group 180 example, wherein male 90 example, women 90 example, age 2-46 year, 21.8 years old mean age, course of disease 1-11, average 5.7 years.Two groups of conditions of patients qualifications and record of service are basically identical, without significant difference, have comparability, keep on a diet all on request for two groups.
2, treatment group patient takes Chinese medicine preparation of the present invention, oral, every day three times, each 3, within ten days, is a course for the treatment of, takes six to eight courses for the treatment of continuously, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding; Matched group uses ecliptic benefit HUOLUO YOU, requires to use in strict accordance with description.
3, Outcome measure:
(1) cure: the symptom such as nerve, muscle, skeleton atrophy takes a turn for the better gradually, finally fully recovers.
(2) take a turn for the better: above-mentioned symptom is alleviated to some extent.
(3) invalid: symptom is unchanged.
4, therapeutic outcome:
Treatment group: cure 101 examples, take a turn for the better 68 examples, and invalid 11 examples, total effective rate is 93.9%.
Matched group: cure 41 examples, take a turn for the better 72 examples, and without turning 67 examples, total effective rate is 62.8%.
Above result display, the total effective rate for the treatment of group is apparently higher than matched group.
Model case is illustrated:
1, Pueraria lobota, man, 18 years old, people from Nanchang.Once infected infantile paralysis when 2 years old disease, and after treatment, right leg muscle atrophy is comparatively serious, has the toe compared in the order of severity, but can stand, walk voluntarily and run, and footslog slightly far understands some pain, and take 6 courses for the treatment of of Chinese medicine preparation of the present invention, recovery from illness, has no recurrence.
2, Chen Huan, female, 24 years old, people from Foochow, Fujian.Once send out rich when 2 years old, burn to step back and find two lower extremity motor function obstacle, that holds up can not stand, and companion L right eye ball esotropia be poliomyelitis sequela after diagnosing, takes 7 courses for the treatment of of Chinese medicine preparation of the present invention, fully recovers, have no recurrence.
3, bent certain, man, 32 years old, people from Xuzhou.Cause hour once suffered from poliomyelitis, and sequela is that left side shank is walked partially outer, and right lower limb is also slightly influenced.Therefore to her personality, work, marriage, is all greatly affected.Introduce through friend, take 7 courses for the treatment of of Chinese medicine preparation of the present invention, additional carefulness is taken exercise, and the state of an illness is fully recovered.