CN103446274B - Traditional Chinese medicine oral liquid for treating infantile scarlet fever and preparation method thereof - Google Patents

Traditional Chinese medicine oral liquid for treating infantile scarlet fever and preparation method thereof Download PDF

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CN103446274B
CN103446274B CN201310405059.4A CN201310405059A CN103446274B CN 103446274 B CN103446274 B CN 103446274B CN 201310405059 A CN201310405059 A CN 201310405059A CN 103446274 B CN103446274 B CN 103446274B
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oral liquid
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李秀玲
宋良芳
董良红
许光锐
王开旭
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Qidong Tianfen Electric Tool Technology Innovation Center
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李秀玲
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Abstract

The invention provides a traditional Chinese medicine oral liquid for treating infantile scarlet fever. The oral liquid is prepared from the following main raw materials in parts by weight: 10 to 30 parts of honeysuckle, 10 to 30 parts of fructus arctii, 10 to 30 parts of puffball mushroom, 20 to 40 parts of mint, 20 to 40 parts of platycodon grandiflorum, 5 to 15 parts of pears and 10 to 30 parts of rock candy. The curative effect of the traditional Chinese medicine oral liquid provided by the invention is remarkable to infantile scarlet fever, by adoption of the oral liquid, not only the fever, headache, pharyngalgia, nausea, vomiting, angina caused by the scarlet fever can be treated more rapidly, but also an excellent curative effect is provided to symptoms such as widespread red tetter; furthermore, with the addition of the pear and the rock candy, the bitter taste in the traditional Chinese medicines can be reduced, therefore the oral liquid is beneficial for children to take, and the traditional Chinese medicine oral liquid is the safe, effective and no-side-effect traditional Chinese medicine oral liquid for treating infantile scarlet fever.

Description

One is treated scarlatinous Chinese medicine oral liquid of children's and preparation method thereof
Technical field
The invention discloses a kind of Chinese medicine oral liquid, especially one is treated scarlatinous Chinese medicine oral liquid of children's and preparation method thereof.The invention belongs to Chinese medicine field.
Background technology
Scarlet fever is that A group β type Hemolytic streptococcus (also referred to as streptococcus pyogenes) infects the Acute respiratory infectious disease causing.Its Clinical symptoms is that heating, angina, whole body diffusivity cerise erythra and rash are stepped back obvious desquamation.After small number of patients is ill, can there is the infringement in the allergy heart, kidney, joint.
Toxin and protease that the pathogenicity of A group β type Hemolytic streptococcus derives from antibacterial itself and produces.The M albumen of antibacterial itself and bacterial capsule can be resisted the cytophagous effect of body, under the effect such as streptokinase, hyaluronidase, inflammation are spread and cause tissue necrosis.The toxin producing comprises pyrogenic exotoxin (being erythrogenic toxin) and hemolysin: the former can cause heating, make skin heart congestion and edema, epithelial cell proliferation, and leukocyte infiltration forms scarlet fever sample erythra; Erythrogenic toxin, except outside the Pass having with various immunoreation and cell effect, can also cause pyrogenicity reaction and skin erythema reaction to the allergy of the various products of streptococcus by enhancing body.Haemolysis have lysed erythrocyte, kills and wounds leukocyte, platelet and damage heart etc.And toxin enters after blood, cause the performance of whole body toxemia, as heating, dizziness, headache etc.The protease producing comprises streptokinase, hyaluronidase, streptodornase, HAД enzyme and serum turbidity factor, causes host tissue and cytoclasis, inflammation to spread and causes tissue necrosis.A family streptococcus has and exceedes 100 kinds of M albumen serotypes, the anti-M protein antibodies producing after organism infection is only to resist the subinfection again of homotype antibacterial, between the each serotype of antibacterial immunity obtaining after organism infection, there is no cross-immunity, may repeatedly there is scarlet fever in child therefore.
Scarlet fever is mainly comprehensively formed by suppurative, toxic and allergy pathological changes, and causes corresponding pathological change.
1. purulent lesion: A group B streptococcus is mainly attached on host cell by the fat Teichaic acid of cell wall after infecting body, because the antiphagocytosis of its M albumen is bred rapidly, and produce hemolysin, extracellular toxin, make host cell death, and by destroying the defence barrier of body tissue, make to infect and spread, cause suppurative change.
2. toxic pathological changes: for toxin enters the whole body toxemia performance causing after blood.Skin: cause skin heart hyperemia, edema, epithelial cell proliferation, leukocyte infiltration, the most obvious around with hair follicle, form typical scarlet fever sample erythra, last epidermis death comes off, and forms " desquamation ".Mucosa: also hemorrhage as seen, form " endanthem ".Liver, spleen, lymph node: visible interstitial blood vessel has monocyte infiltration and hyperemia in various degree, steatosis around.Cardiac muscle: can have cloudy swelling and degeneration, severe one can be downright bad.Kidney is interstitial inflammation.
3. allergy pathological changes: main manifestations is the heart, kidney and synovium of joint capsule serous inflammation, reason may be organized with A the antigen generation cross-immune reaction of some type of Hemolytic streptococcus and sufferer's cardiac muscle, glomerular basement membrane or synovium of joint, may be also to have formed antigen antibody complex to be deposited on above-mentioned position and to cause immunologic injury.
Compare with western medicine and medical practitioners, by Chinese traditional treatment, toxic and side effects is lighter, is more vulnerable to numerous medical personnels
Favor with friend patient.Granted publication CN 102614394 A(application numbers 201210036690.7) Chinese patent literary composition
Offer and provide for the purple Bai Pitang of scarlatinous silver, comprise stock and adjunct, composition of raw materials proportioning is Flos Lonicerae, Radix Arnebiae (Radix Lithospermi), Radix Asteris, Cacumen Platycladi, Cortex Moutan, Folium Mori, Radix Rubiae, the Radix Angelicae Dahuricae, Scorpio, Bombyx Batryticatus, the Radix Paeoniae Alba, Radix Puerariae, Cortex Lycii, Radix Saposhnikoviae, Rhizoma Imperatae, Semen Plantaginis, Radix Glycyrrhizae composition.Granted publication CN 102133348 A(application numbers 201110046684.5) Chinese patent literature relate to one and treat scarlatinous Chinese medicine, this Chinese medicine is with Folium Nelumbinis, Radix Sophorae Tonkinensis, Folium Isatidis, Radix Glycyrrhizae, Folium Mori, Flos Lonicerae, Flos Chrysanthemi, Fructus Forsythiae, Radix Sophorae Flavescentis, Cortex Lycii, Radix et Caulis Opuntiae Dillenii, Caulis Lonicerae, Succus Bambusae, Radix Bupleuri, the Rhizoma Anemarrhenae and Herba Commelinae are activated feedstock, existing is all the scarlatinous Chinese medicine formula for the treatment of adult, cut Chinese medicine figure place used numerous, bitter in the mouth children's is unwilling to take.
Summary of the invention
For the present situation for the treatment of children's scarlet fever deficiency, one of object of the present invention is to provide one to treat the scarlatinous Chinese medicine oral liquid of children's, and the present invention prepares simply, good absorbing effect, evident in efficacy, have no side effect, safe, be conducive to sufferer and alleviate in time condition of illness.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicine oral liquid.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
One is treated the scarlatinous Chinese medicine oral liquid of children's, takes off the primary raw material of stating weight proportion and is prepared from: Flos Lonicerae 10-30 part, Fructus Arctii 10-30 part, Lasiosphaera Seu Calvatia 10-30 part, Herba Menthae 20-40 part, Radix Platycodonis 20-40 part, pear 5-15 part, crystal sugar 10-30 part.
One is treated the scarlatinous Chinese medicine oral liquid of children's, and preferred scheme is: take off the primary raw material of stating weight proportion and be prepared from: Flos Lonicerae 15-25 part, Fructus Arctii 15-25 part, Lasiosphaera Seu Calvatia 15-25 part, Herba Menthae 15-25 part, Radix Platycodonis 25-35 part, pear 8-13 part, crystal sugar 15-25 part.
One is treated the scarlatinous Chinese medicine oral liquid of children's, and the scheme being more preferably is: take off the primary raw material of stating weight proportion and be prepared from: 20 parts of Flos Loniceraes, 20 parts of Fructus Arctiis, 20 parts of Lasiosphaera Seu Calvatia, 20 parts of Herba Menthaes, 30 parts of Radix Platycodoniss, 10 parts of pears, 20 parts, crystal sugar.
The preparation method of above-mentioned Chinese medicine oral liquid, preferred scheme is that step is as follows:
1. mentha leave is put into pressure cooker, connect long leather hose that has certain degree of hardness in gas outlet, then, by cooling in one section of leather hose immersion cold water wherein, another section of leather hose connects a carafe, then separates the oil on upper strata, and the oil of separating is exactly Oleum menthae.
2. Flos Lonicerae, Fructus Arctii, Lasiosphaera Seu Calvatia and Radix Platycodonis are decocted with water 2 times, decoct for the first time 1.5-2.5 hour, filter, obtain filtrate 1, the filtering residue after filtering is added water and decocted for the second time, decoct 1.5 hours, obtain filtrate 2, filtrate 1 is mixed and decocted 1 hour again with filtrate 2, leave standstill 20-30 hour, again filter, obtain filtrate for subsequent use;
3. pear and crystal sugar are put into 2. institute's filtrate of step, slow fire boiling 5-15 minute, leaves standstill cooling 1-2 hour after filtering;
4. by step 1. in gained Oleum menthae drip in step 3. in the cooled filtrate of gained, the 0.1-0.5 that the consumption of Oleum menthae is filtrate doubly, mix homogeneously both Chinese medicine oral liquid of the present invention.
Above-mentioned preparation method, preferred scheme is: the step 1. ratio of mentha leave and water is 1:10, and the half of the pressure cooker that adds water is just passable, can not exceed at most 2/3 height.
Above-mentioned preparation method, preferred scheme is: 2. step decocts 1.8-2.3 hour (preferably 2 hours).
Above-mentioned preparation method, preferred scheme is: 2. step leaves standstill 23-28 hour (preferably 25 hours).
Above-mentioned preparation method, preferred scheme is: step 3. culture decocts 8-13 minute (preferably 10 minutes).
Above-mentioned preparation method, preferred scheme is: 3. step leaves standstill cooling 1.3-1.8 hour (preferably 1.5 hours).
Above-mentioned preparation method, preferred scheme is: the step 0.2-0.4 that 4. consumption of Oleum menthae is filtrate is (preferably 0.3 times) doubly.
Using method: for making the present invention reach optimum therapeuticing effect, when edible, after 1 hour, take after the meal, 3 times on the one, each serving using 2ml-6ml.
Chinese medicine oral liquid of the present invention is remarkable to the scarlatinous effect for the treatment of children's, can not only treat faster heating, headache, pharyngalgia that scarlet fever causes, feel sick, vomiting, angina, also the symptoms such as whole body diffusivity cerise erythra be had to good therapeutic effect, and the bitterness that has added crystal sugar and pear in the present invention and can reduce Chinese medicine, is beneficial to children taking.
One is treated the scarlatinous Chinese medicine oral liquid of children's, and the pharmacological effect of each crude drug is respectively:
Flos Lonicerae: Flos Lonicerae is cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has effect of heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treatment wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.Flos Lonicerae tea has unique weight losing function simultaneously, can also suppress and the pathogen of killing bottleneck throat, and old man and child are had to infection effect.So, often take Flos Lonicerae immersion or decoct and be conducive to wind-fire conjunctival congestion, laryngopharynx swelling and pain, obesity, the hypertensive treatment of liver-heat disease regulating liver-QI pattern of fever and rehabilitation.
Fructus Arctii: acrid in the mouth; Bitter; Cold in nature.Return lung; Stomach warp.Dispelling wind and heat pathogens; Heat-clearing and toxic substances removing rash; Lung qi dispersing sore-throat relieving is loose swollen.Anemopyretic cold, epidemic febrile disease from the beginning of; Wind heat or cough due to lung-heat, cough up phlegm not smooth; Laryngopharynx swelling and pain; Macule is not saturating; At the measles initial stage, rash goes out not smooth and rubella pruritus; Sore swollen toxin and mumps etc.Raw with can loosening bowel to relieve constipation, pyretic toxicity red swelling and pain of throat, has constipation with heat retention concurrently especially suitable.For the not yet routed person of hot carbuncle toxin, normal and Herba Violae, the heat and toxic materials clearing away medicine compatibilities such as Flos Chrysanthemi Indici.
Lasiosphaera Seu Calvatia: mainly as local hemostatic, double throat pain, the aphonia etc. controlled.
Herba Menthae: pungent, cool.Dispelling wind, dispel the heat, ward off dirty, removing toxic substances, affection due to external wind and heat, headache, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria, epidemic febrile disease from the beginning of, rubella pruritus, stagnation of QI due to depression of the liver, hypochondriac pain uncomfortable in chest.
Radix Platycodonis: bitter in the mouth; Pungent; Property is put down.Cough with copious phlegm, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache, aphtha of the mouth and tongue, conjunctival congestion and swelling pain, uroschesis.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Pear: a kind of common fruit, the tender Bai Ruxue of meat, so gain the name.Sweet in the mouth is cold in nature, tool promote the production of body fluid moisturize, effect of removing heat-phlegm, nourishing blood and promoting granulation.
Crystal sugar: crystal sugar sweet in the mouth, property are put down, and enter lung, spleen channel; There is invigorating the spleen and replenishing QI, effect of stomach function regulating lung moistening; Crystal sugar YIN nourishing and the production of body fluid promoting, nourishing the lung to arrest cough, has good auxiliary therapeutic action to xeropulmonary cough, dry cough without phlegm, sputum with blood; For cough with asthma, infantile malaria, fasting dysentery, aphtha, acute toothache due to the dryness of the lung, the deficiency of the lung, wind and cold fatigue.
Chinese medicine oral liquid of the present invention is based on the scarlatinous principle of traditional Chinese medical herbal treatment children's.Adopt the Chinese medicine all with treatment scarlet fever symptom, cheap, life-time service also can not cause patient's financial burden, is the comparatively desirable medicine for the treatment of children's scarlet fever.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1one is treated the scarlatinous Chinese medicine oral liquid of children's, takes off the primary raw material of stating weight proportion and is prepared from: 10 parts of Flos Loniceraes, 10 parts of Fructus Arctiis, 10 parts of Lasiosphaera Seu Calvatia, 20 parts of Herba Menthaes, 20 parts of Radix Platycodoniss, 5 parts of pears, 10 parts, crystal sugar.
The preparation method of above-mentioned Chinese medicine oral liquid, step is:
1. mentha leave is put into pressure cooker, connect long leather hose that has certain degree of hardness in gas outlet, then, by cooling in one section of leather hose immersion cold water wherein, another section of leather hose connects a carafe, then separates the oil on upper strata, and the oil of separating is exactly Oleum menthae.
2. Flos Lonicerae, Fructus Arctii, Lasiosphaera Seu Calvatia and Radix Platycodonis are decocted with water 2 times, decoct for the first time 1.5 hours, filter, obtain filtrate 1, the filtering residue after filtering is added water and decocted for the second time, decoct 1.5 hours, obtain filtrate 2, filtrate 1 is mixed and decocted 1 hour again with filtrate 2, leave standstill 20 hours, again filter, obtain filtrate for subsequent use;
3. pear and crystal sugar are put into 2. institute's filtrate of step, slow fire boiling 5 minutes, leaves standstill cooling 1 hour after filtering;
4. by step 1. in gained Oleum menthae drip in step 3. in the cooled filtrate of gained, the consumption of Oleum menthae is filtrate 0.1 times, mix homogeneously both Chinese medicine oral liquid of the present invention.
model case one, grandson XX, female, 1 years old.People from Shenxian County, Liaocheng of Shandong Province, according to the large head of a family of child, child usually has the phenomenon of persistent fever, and all can continue 3-5 days at every turn, body temperature is all in 39 degree left and right, each hyperpyrexia just starts to have pharyngalgia after decorporating, and dare not having a meal, it is all very difficult to drink water, whole body diffusivity cerise erythra, through with after penicillin, the sheet of bringing down a fever, symptom is improved not obvious, and erythra progressively increases.Go examination in hospital doctor to say: leucocytosis.The head of a family's fearing very, doctor recommends them to take Chinese medicine oral liquid of the present invention to child, while taking 3 days, burns and has taken off, and pharyngalgia has also alleviated, and continues to take 1 course for the treatment of, and symptom disappears completely, recovers normal.
embodiment 2one is treated the scarlatinous Chinese medicine oral liquid of children's, takes off the primary raw material of stating weight proportion and is prepared from: 30 parts of Flos Loniceraes, 30 parts of Fructus Arctiis, 30 parts of Lasiosphaera Seu Calvatia, 40 parts of Herba Menthaes, 40 parts of Radix Platycodoniss, 15 parts of pears, 30 parts, crystal sugar.
The preparation method of above-mentioned Chinese medicine oral liquid, step is:
1. mentha leave is put into pressure cooker, connect long leather hose that has certain degree of hardness in gas outlet, then, by cooling in one section of leather hose immersion cold water wherein, another section of leather hose connects a carafe, then separates the oil on upper strata, and the oil of separating is exactly Oleum menthae.
2. Flos Lonicerae, Fructus Arctii, Lasiosphaera Seu Calvatia and Radix Platycodonis are decocted with water 2 times, decoct for the first time 2.5 hours, filter, obtain filtrate 1, the filtering residue after filtering is added water and decocted for the second time, decoct 1.5 hours, obtain filtrate 2, filtrate 1 is mixed and decocted 1 hour again with filtrate 2, leave standstill 30 hours, again filter, obtain filtrate for subsequent use;
3. pear and crystal sugar are put into 2. institute's filtrate of step, slow fire boiling 15 minutes, leaves standstill cooling 2 hours after filtering;
4. by step 1. in gained Oleum menthae drip in step 3. in the cooled filtrate of gained, the consumption of Oleum menthae is filtrate 0.5 times, mix homogeneously both Chinese medicine oral liquid of the present invention.
embodiment 3one is treated the scarlatinous Chinese medicine oral liquid of children's, takes off the primary raw material of stating weight proportion and is prepared from: 15 parts of Flos Loniceraes, 15 parts of Fructus Arctiis, 15 parts of Lasiosphaera Seu Calvatia, 15 parts of Herba Menthaes, 25 parts of Radix Platycodoniss, 8 parts of pears, 15 parts, crystal sugar.
The preparation method of above-mentioned Chinese medicine oral liquid, step is:
1. mentha leave is put into pressure cooker, connect long leather hose that has certain degree of hardness in gas outlet, then, by cooling in one section of leather hose immersion cold water wherein, another section of leather hose connects a carafe, then separates the oil on upper strata, and the oil of separating is exactly Oleum menthae.
2. Flos Lonicerae, Fructus Arctii, Lasiosphaera Seu Calvatia and Radix Platycodonis are decocted with water 2 times, decoct for the first time 1.8 hours, filter, obtain filtrate 1, the filtering residue after filtering is added water and decocted for the second time, decoct 1.5 hours, obtain filtrate 2, filtrate 1 is mixed and decocted 1 hour again with filtrate 2, leave standstill 23 hours, again filter, obtain filtrate for subsequent use;
3. pear and crystal sugar are put into 2. institute's filtrate of step, slow fire boiling 8 minutes, leaves standstill cooling 1.3 hours after filtering;
4. by step 1. in gained Oleum menthae drip in step 3. in the cooled filtrate of gained, the consumption of Oleum menthae is filtrate 0.2 times, mix homogeneously both Chinese medicine oral liquid of the present invention.
typical case twolee X, female, 6 years old, people from Shangqiu, Henan, went up kindergarten now.Patient's general malaise 2 days, high fever, whole body diffusivity cerise erythra were gone to a doctor in April, 2010, and patient body is fatter, and blood vessel is unclear, refusal injection penicillin.Infant mother very worry, child's grandmother has heard that in rural area Chinese medicine oral liquid of the present invention just privately bought 2 courses for the treatment of and taken to child, does mother of child think while just beginning that earthwork among the people can be effective? child's grandmother has taken Chinese medicine oral liquid of the present invention to child firmly, take 1 o'clock, burn and just backed off, it is very magical that mother of child also feels, just continues to have taken a course for the treatment of to child, clinical symptoms disappears completely, does not recur again.
embodiment 4one is treated the scarlatinous Chinese medicine oral liquid of children's, takes off the primary raw material of stating weight proportion and is prepared from: 25 parts of Flos Loniceraes, 25 parts of Fructus Arctiis, 25 parts of Lasiosphaera Seu Calvatia, 25 parts of Herba Menthaes, 35 parts of Radix Platycodoniss, 13 parts of pears, 25 parts, crystal sugar.
The preparation method of above-mentioned Chinese medicine oral liquid, step is:
1. mentha leave is put into pressure cooker, connect long leather hose that has certain degree of hardness in gas outlet, then, by cooling in one section of leather hose immersion cold water wherein, another section of leather hose connects a carafe, then separates the oil on upper strata, and the oil of separating is exactly Oleum menthae.
2. Flos Lonicerae, Fructus Arctii, Lasiosphaera Seu Calvatia and Radix Platycodonis are decocted with water 2 times, decoct for the first time 2.3 hours, filter, obtain filtrate 1, the filtering residue after filtering is added water and decocted for the second time, decoct 1.5 hours, obtain filtrate 2, filtrate 1 is mixed and decocted 1 hour again with filtrate 2, leave standstill 28 hours, again filter, obtain filtrate for subsequent use;
3. pear and crystal sugar are put into 2. institute's filtrate of step, slow fire boiling 13 minutes, leaves standstill cooling 1.8 hours after filtering;
4. by step 1. in gained Oleum menthae drip in step 3. in the cooled filtrate of gained, the consumption of Oleum menthae is filtrate 0.4 times, mix homogeneously both Chinese medicine oral liquid of the present invention.
embodiment 5one is treated the scarlatinous Chinese medicine oral liquid of children's, takes off the primary raw material of stating weight proportion and is prepared from: 20 parts of Flos Loniceraes, 20 parts of Fructus Arctiis, 20 parts of Lasiosphaera Seu Calvatia, 20 parts of Herba Menthaes, 30 parts of Radix Platycodoniss, 10 parts of pears, 20 parts, crystal sugar.
1. mentha leave is put into pressure cooker, connect long leather hose that has certain degree of hardness in gas outlet, then, by cooling in one section of leather hose immersion cold water wherein, another section of leather hose connects a carafe, then separates the oil on upper strata, and the oil of separating is exactly Oleum menthae.
2. Flos Lonicerae, Fructus Arctii, Lasiosphaera Seu Calvatia and Radix Platycodonis are decocted with water 2 times, decoct for the first time 2 hours, filter, obtain filtrate 1, the filtering residue after filtering is added water and decocted for the second time, decoct 1.5 hours, obtain filtrate 2, filtrate 1 is mixed and decocted 1 hour again with filtrate 2, leave standstill 25 hours, again filter, obtain filtrate for subsequent use;
3. pear and crystal sugar are put into 2. institute's filtrate of step, slow fire boiling 10 minutes, leaves standstill cooling 1.5 hours after filtering;
4. by step 1. in gained Oleum menthae drip in step 3. in the cooled filtrate of gained, the consumption of Oleum menthae is filtrate 0.3 times, mix homogeneously both Chinese medicine oral liquid of the present invention.
experimental exampleobject is to verify whether this Chinese medicine oral liquid has curative effect to treatment children's scarlet fever.
" the new Chinese medicine guideline of clinical investigations " within 1993, formulated according to Ministry of Public Health is diagnosis basis, totally 200 routine children's scarlet fever patients, and the mean age is 2 years old.Random division is administration group and matched group.
Before experiment one day, records patient's health, looks over patient body symptom every day, guarantees that administration group and matched group situation are basically identical.Administration group is taken this product embodiments 5 gained Chinese medicine oral liquid every day, within 7 days, is a course for the treatment of.Check patient body situation every day, make a record.Result is as following table 1:
Table 1:
efficacy analysis:administration group (Chinese medicine oral liquid of the present invention) is used most patient sensory symptoms 7 days time obviously to alleviate, and obviously feels to take a favorable turn in affected part, and patient's emotion takes a turn for the better, and when medication 10 days, patient is almost recovered, and drug withdrawal a period of time has no repeatedly, and the state of an illness is better controlled.Matched group take medicine after curative effect obvious, but after drug withdrawal, 94% patient is recurred again.
Prove through clinical trial, Chinese medicine oral liquid of the present invention is on treatment children's scarlet fever, and effective percentage is 98%, and cure rate is 95%, exceeds 28% than oral western medicine effective percentage, and cure rate exceeds 20%, and can thoroughly remove old complaint, makes the real recovery from illness of patient; And can not cause any burden to patient's health.Chinese medicine oral liquid instant effect of the present invention, can reach the object of rapid alleviation patient misery, and relapse rate is low, is that one is treated the scarlatinous Chinese medicine oral liquid of children's safely and effectively.

Claims (14)

1. a treatment children's scarlatinous Chinese medicine oral liquid, is characterized in that: take off the crude drug of stating weight proportion and be prepared from: Flos Lonicerae 10-30 part, Fructus Arctii 10-30 part, Lasiosphaera Seu Calvatia 10-30 part, Herba Menthae 20-40 part, Radix Platycodonis 20-40 part, pear 5-15 part, crystal sugar 10-30 part.
2. Chinese medicine oral liquid according to claim 1, is characterized in that: take off the crude drug of stating weight proportion and be prepared from: Flos Lonicerae 15-25 part, Fructus Arctii 15-25 part, Lasiosphaera Seu Calvatia 15-25 part, Herba Menthae 15-25 part, Radix Platycodonis 25-35 part, pear 8-13 part, crystal sugar 15-25 part.
3. Chinese medicine oral liquid according to claim 1, is characterized in that: take off the crude drug of stating weight proportion and be prepared from: 20 parts of Flos Loniceraes, 20 parts of Fructus Arctiis, 20 parts of Lasiosphaera Seu Calvatia, 20 parts of Herba Menthaes, 30 parts of Radix Platycodoniss, 10 parts of pears, 20 parts, crystal sugar.
4. according to the preparation method of the arbitrary described Chinese medicine oral liquid of claim 1-3, it is characterized in that, step is as follows:
Mentha leave is put into pressure cooker, connect long leather hose that has certain degree of hardness in gas outlet, then, by cooling in one section of leather hose immersion cold water wherein, another section of leather hose connects a carafe, then separates the oil on upper strata, and the oil of separating is exactly Oleum menthae;
2. Flos Lonicerae, Fructus Arctii, Lasiosphaera Seu Calvatia and Radix Platycodonis are decocted with water 2 times, decoct for the first time 1.5-2.5 hour, filter, obtain filtrate 1, the filtering residue after filtering is added water and decocted for the second time, decoct 1.5 hours, obtain filtrate 2, filtrate 1 is mixed and decocted 1 hour again with filtrate 2, leave standstill 20-30 hour, again filter, obtain filtrate for subsequent use;
3. pear and crystal sugar are put into 2. gained filtrate of step, slow fire boiling 5-15 minute, leaves standstill cooling 1-2 hour after filtering;
4. by step 1. in gained Oleum menthae drip in step 3. in the cooled filtrate of gained, doubly, mix homogeneously obtains Chinese medicine oral liquid to the 0.1-0.5 that the consumption of Oleum menthae is filtrate.
5. preparation method according to claim 4, is characterized in that: 2. step decocts 1.8-2.3 hour.
6. preparation method according to claim 5, is characterized in that: 2. step decocts 2 hours.
7. preparation method according to claim 4, is characterized in that: 2. step leaves standstill 23-28 hour.
8. preparation method according to claim 7, is characterized in that: 2. step leaves standstill 25 hours.
9. preparation method according to claim 4, is characterized in that: step is slow fire boiling 8-13 minute 3..
10. preparation method according to claim 9, is characterized in that: 3. slow fire boiling 10 minutes of step.
11. preparation methoies according to claim 4, is characterized in that: 3. step leaves standstill cooling 1.3-1.8 hour.
12. preparation methoies according to claim 11, is characterized in that: 3. step leaves standstill cooling 1.5 hours.
13. preparation methoies according to claim 4, is characterized in that: the step 0.2-0.4 that 4. consumption of Oleum menthae is filtrate doubly.
14. preparation methoies according to claim 13, is characterized in that: the step 4. consumption of Oleum menthae is filtrate 0.3 times.
CN201310405059.4A 2013-09-09 2013-09-09 Traditional Chinese medicine oral liquid for treating infantile scarlet fever and preparation method thereof Active CN103446274B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102133348A (en) * 2011-02-28 2011-07-27 辛如才 Traditional Chinese medicine for treating scarflet fever
CN102614394A (en) * 2012-02-11 2012-08-01 高迎文 Silver purple cypress skin soup for scarlatina

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102133348A (en) * 2011-02-28 2011-07-27 辛如才 Traditional Chinese medicine for treating scarflet fever
CN102614394A (en) * 2012-02-11 2012-08-01 高迎文 Silver purple cypress skin soup for scarlatina

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