CN103446089B - Incarviatone A在制备治疗鼻咽癌药物中的应用 - Google Patents
Incarviatone A在制备治疗鼻咽癌药物中的应用 Download PDFInfo
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- CN103446089B CN103446089B CN201310432193.3A CN201310432193A CN103446089B CN 103446089 B CN103446089 B CN 103446089B CN 201310432193 A CN201310432193 A CN 201310432193A CN 103446089 B CN103446089 B CN 103446089B
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- nasopharyngeal
- incarviatone
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- 239000003814 drug Substances 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 150000001875 compounds Chemical class 0.000 claims description 17
- 208000002454 Nasopharyngeal Carcinoma Diseases 0.000 abstract description 13
- 206010061306 Nasopharyngeal cancer Diseases 0.000 abstract description 13
- 201000011216 nasopharynx carcinoma Diseases 0.000 abstract description 13
- 230000012010 growth Effects 0.000 abstract description 7
- 101150080924 CNE1 gene Proteins 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 6
- 230000002401 inhibitory effect Effects 0.000 abstract description 4
- 230000000118 anti-neoplastic effect Effects 0.000 abstract description 2
- 238000011161 development Methods 0.000 abstract description 2
- 238000011156 evaluation Methods 0.000 abstract description 2
- 229940079593 drug Drugs 0.000 description 4
- 239000002246 antineoplastic agent Substances 0.000 description 3
- 229940041181 antineoplastic drug Drugs 0.000 description 3
- 239000001963 growth medium Substances 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 230000031700 light absorption Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229930014626 natural product Natural products 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 241001597008 Nomeidae Species 0.000 description 1
- 229930012538 Paclitaxel Natural products 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 230000001464 adherent effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 239000012531 culture fluid Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 231100000206 health hazard Toxicity 0.000 description 1
- 150000002611 lead compounds Chemical class 0.000 description 1
- 238000011275 oncology therapy Methods 0.000 description 1
- 229960001592 paclitaxel Drugs 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
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Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201310432193.3A CN103446089B (zh) | 2013-09-22 | 2013-09-22 | Incarviatone A在制备治疗鼻咽癌药物中的应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201310432193.3A CN103446089B (zh) | 2013-09-22 | 2013-09-22 | Incarviatone A在制备治疗鼻咽癌药物中的应用 |
Publications (2)
Publication Number | Publication Date |
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CN103446089A CN103446089A (zh) | 2013-12-18 |
CN103446089B true CN103446089B (zh) | 2015-12-02 |
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Application Number | Title | Priority Date | Filing Date |
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CN201310432193.3A Active CN103446089B (zh) | 2013-09-22 | 2013-09-22 | Incarviatone A在制备治疗鼻咽癌药物中的应用 |
Country Status (1)
Country | Link |
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CN (1) | CN103446089B (zh) |
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2013
- 2013-09-22 CN CN201310432193.3A patent/CN103446089B/zh active Active
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CN103446089A (zh) | 2013-12-18 |
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C41 | Transfer of patent application or patent right or utility model | ||
CB03 | Change of inventor or designer information |
Inventor after: Zhang Hongli Inventor before: Jiang Chunping Inventor before: Huang Rong |
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Effective date of registration: 20151103 Address after: 325011, building 1112, building A, 209 Wenchang Road, hi tech Zone, Longwan District, Zhejiang, Wenzhou Applicant after: Wenzhou Chengqiao Technology Co.,Ltd. Address before: Metro Technology Building No. 69 Olympic Avenue in Jianye District of Nanjing city in Jiangsu province 210019 01 5 storey buildings Applicant before: Nanjing guangkangxie Biomedical Technology Co.,Ltd. |
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Effective date of registration: 20181206 Address after: 233010 409 Wu Wan Road, Yuhui District, Bengbu, Anhui Patentee after: BENGBU JINSHI NEW MATERIAL Co.,Ltd. Address before: 230031 B-1014, 10 floor, business office building, Wo Ye garden, Shushan District, Hefei, Anhui. Patentee before: HEFEI WISDOM LOTUT INTELLECTUAL PROPERTY Co.,Ltd. Effective date of registration: 20181206 Address after: 230031 B-1014, 10 floor, business office building, Wo Ye garden, Shushan District, Hefei, Anhui. Patentee after: HEFEI WISDOM LOTUT INTELLECTUAL PROPERTY Co.,Ltd. Address before: 325011 room 1112, building A, 209 Wenchang Road, hi tech Zone, Longwan District, Wenzhou, Zhejiang. Patentee before: Wenzhou Chengqiao Technology Co.,Ltd. |
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Effective date of registration: 20190411 Address after: 510000 Room 520, Five Floors, No. 1 Ruifa Road, Huangpu District, Guangzhou City, Guangdong Province Patentee after: Guangzhou Huizhi Successful Pharmaceutical Research Co.,Ltd. Address before: 233010 409 Wu Wan Road, Yuhui District, Bengbu, Anhui Patentee before: BENGBU JINSHI NEW MATERIAL Co.,Ltd. |