CN103432490A - Traditional Chinese medicine composition for treating cough - Google Patents

Traditional Chinese medicine composition for treating cough Download PDF

Info

Publication number
CN103432490A
CN103432490A CN2013103434686A CN201310343468A CN103432490A CN 103432490 A CN103432490 A CN 103432490A CN 2013103434686 A CN2013103434686 A CN 2013103434686A CN 201310343468 A CN201310343468 A CN 201310343468A CN 103432490 A CN103432490 A CN 103432490A
Authority
CN
China
Prior art keywords
parts
cough
radix
chinese medicine
medicine composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN2013103434686A
Other languages
Chinese (zh)
Other versions
CN103432490B (en
Inventor
张跃
严生虎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhuhai Hengqin Maikairui Pharmaceutical Technology Co ltd
Original Assignee
HAIAN CHANGZHOU UNIVERSITY TECHNOLOGY TRANSFER CENTER Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HAIAN CHANGZHOU UNIVERSITY TECHNOLOGY TRANSFER CENTER Co Ltd filed Critical HAIAN CHANGZHOU UNIVERSITY TECHNOLOGY TRANSFER CENTER Co Ltd
Priority to CN201310343468.6A priority Critical patent/CN103432490B/en
Publication of CN103432490A publication Critical patent/CN103432490A/en
Application granted granted Critical
Publication of CN103432490B publication Critical patent/CN103432490B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a traditional Chinese medicine composition for treating a cough. The traditional Chinese medicine composition comprises the following crude drugs in parts by weight: 17 parts of lilium brownii, 14 parts of cordate houttuynia, 15 parts of peach kernels, 17 parts of liquorice, 16 parts of fructus forsythiae, 12 parts of apricot kernels, 14 parts of indian buead, 9 parts of dwarf lilyturf turber, 13 parts of adenophora stricta, 14 parts of rhizoma anemarrhenae, 11 parts of platycladi seeds, 13 parts of fritillary, 17 parts of platycodon grandiflorum, 10 parts of scutellaria baicalensis, 15 parts of mint, 14 parts of radix stemonae, 16 parts of honeysuckle, 3 parts of angelica, 14 parts of fructus crataegi and 5 parts of semen plantaginis.

Description

The Chinese medicine composition for the treatment of cough
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of cough.
Background technology
Lung is that one of main syndromes of illness is exactly cough.Throughout history, ancient Chinese medicine doctor has different opinion for cough.Huangdi's Internal Classics proposes the demonstration of " vital organs of the human body all make us coughing, and non-only lung also " ".Jing-Yue Complete Works discuss again " card of coughing, surreptitiously be seen in family set forth one's views numerous greatly, neither that it is wanted, cause more the descendant face card Mo Zhisuo from, so control rare effect ".Zhang Jingyue will be coughed card by being divided into diseases caused by exogenous pathogenic factor, internal injury two classes.Mention again " cold and summer-heat dampness wind-fire six gas, all make us coughing " in " the interchannel six scripts ".Cough is disease and syndrome, and any age all can fall ill, and winter-spring season is common.The cause of disease of cough has diseases caused by exogenous pathogenic factor, internal injury not, it is the cough caused that heresy of wind, cold, summer-heat, wet, dry, fiery six climate exopathogens attacked lung, for the exogenous cough, in exopathogen again with wind, cold, heat cough is in the majority, and Chang Yifeng is first number, hold under the arm cold or hold heat under the arm, hold dry criminal's lung under the arm, wind and cold or the coughs such as wind heat, wind-dryness occur; Because lungs virtual loss and other visceral dysfunctions have influence on the cough that lung causes, be the endogenous cough.Normal internal injury, exogenous cough's cross-reference reciprocal causation clinically.Said as " cough of medical science innermost thoughts and feelings ": " the lung body belongs to gold, and such as Zhong Ran, Zhong Fei kowtows and do not ring, and the heresy of wind and cold heat-damp in summer dryness-fire six climate exopathogens is from the ring of hitting outward, and labor is wanted feelings will, and diet is processed the also ring of the fire of Bo from inside fire attack ".
Cough be take differential diagnosis in terms of eight principles as guiding principle, and head distinguishes diseases caused by exogenous pathogenic factor and internal injury, common with the exogenous cough, and it is basic principle that a surname of take sends out lung qi.Wang Shouchuan is divided into wind and cold and the large pattern of syndrome of wind heat two by children's exogenous cough, and Han new people are divided into wind and cold, wind heat and the large pattern of syndrome of wind-dryness three by it, wherein the cough due to wind and cold to take expelling wind and cold, lung qi dispersing cough-relieving be method for the treatment of, with jinfeicao powder, add and subtract; It is method for the treatment of that the cough due to pathogenic wind-heat be take dispelling wind and heat pathogens, lung qi dispersing cough-relieving, with SANGJU YIN, adds and subtracts; It is method for the treatment of that dispelling wind lung heat clearing, nourishing the lung to arrest cough are take in wind-dryness cough, with Decoction for Reliving Dryness of the Lung, adds and subtracts.Zhong Hua etc. distinguish and control the exogenous cough according to children's's body constitution, and it is divided into to four types is normal matter youngster, phlegm-damp matter youngster, deficiency of vital energy matter youngster and deficiency of YIN matter youngster, normal matter youngster take evacuate exopathogen, the lung qi dispersing cough-relieving is method for the treatment of, take Apricot Kernel and Perilla Powder, SANGJU YIN and numb Fructus Pruni Shigao Tang etc. is main formula; It is method for the treatment of that phlegm-damp matter youngster be take the spleen strengthening and damp drying, preventing phlegm from forming and stopping coughing, and the numb Fructus Pruni ERCHEN TANG of take is main formula; Deficiency of vital energy matter youngster be take invigorating the spleen and benefiting QI as method for the treatment of with dispelling wind and ventilating the lung, preventing phlegm from forming and stopping coughing, assistant, in wind and cold or the basic side of wind heat, take the circumstances into consideration to add with resistance and supplementing qi medicines such as the Rhizoma Atractylodis Macrocephalae, the Radixs Astragali, or Liujunzi Tang adds Rhizoma Belamcandae, Herba Houttuyniae, Fructus Forsythiae, Radix Platycodonis etc.
CN102078558A discloses a kind of pharmaceutical composition for the treatment of cough, and wherein the weight proportion of crude drug is as follows: 30 parts of Ramulus Uncariae Cum Uncis, 40 parts of Concretio Silicea Bambusaes, 10 parts of Radix Platycodoniss; 50 parts of Fructus Amomis, 50 parts of Pericarpium Citri Reticulataes, 10 parts, Poria; 50 parts of Herba Menthaes, 20 parts, Radix Glycyrrhizae, 7 parts of Calculus Boviss.
CN101991802A discloses a kind of Chinese medicine preparation for the treatment of cold cough, it contains 30 parts of Flos Loniceraes, 30 parts of Pericarpium Citri Reticulataes, 25 parts of Herba Artemisiae Scopariaes, 35 parts of the Radixs Stemonae, 30 parts, Radix Glycyrrhizae, 25 parts of Semen Armeniacae Amarums, 25 parts of Semen Platycladi, 20 parts of Bulbus Fritillariae Uninbracteataes, 30 parts of Radix Platycodoniss, 20 parts, Fructus Jujubae, 15 parts, dry moxa leaf and appropriate Mel.
Summary of the invention
The invention provides a kind of Chinese medicine composition that is used for the treatment of cough, wherein the weight proportion of crude drug is as follows:
17 parts of Bulbus Liliies, 14 parts of Herba Houttuyniae, 15 parts, Semen Persicae, 17 parts, Radix Glycyrrhizae, 16 parts of Fructus Forsythiaes, 12 parts, Semen Armeniacae Amarum, 14 parts, Poria, 9 parts of Radix Ophiopogonis, 13 parts of Radix Adenophorae (Radix Glehniae), 14 parts of the Rhizoma Anemarrhenaes, 11 parts of Semen Platycladi, 13 parts of Bulbus Fritillariae Uninbracteataes, 17 parts of Radix Platycodoniss, 10 parts of Radix Scutellariaes, 15 parts of Herba Menthaes, 14 parts of the Radixs Stemonae, 16 parts of Flos Loniceraes, 3 parts of Radix Angelicae Sinensis, 14 parts of Fructus Crataegis, 5 parts of Semen Plantaginiss.
Preparation method, for getting above crude drug, is put into container, adds cold water and covers powder, soaks 15~20 minutes, then adds water and do not have approximately 8 centimetres of powder, is decocted.At a simmer, adopt intense fire to decoct, boil rear with slow fire boiling 20~30 minutes; Decoct for the second time the water rear slow fire boiling 15~20 minutes of boiling.Twice decoction extracting juice that removes slag, merge.
The specific embodiment
Embodiment 1
17 parts of Bulbus Liliies, 14 parts of Herba Houttuyniae, 15 parts, Semen Persicae, 17 parts, Radix Glycyrrhizae, 16 parts of Fructus Forsythiaes, 12 parts, Semen Armeniacae Amarum, 14 parts, Poria, 9 parts of Radix Ophiopogonis, 13 parts of Radix Adenophorae (Radix Glehniae), 14 parts of the Rhizoma Anemarrhenaes, 11 parts of Semen Platycladi, 13 parts of Bulbus Fritillariae Uninbracteataes, 17 parts of Radix Platycodoniss, 10 parts of Radix Scutellariaes, 15 parts of Herba Menthaes, 14 parts of the Radixs Stemonae, 16 parts of Flos Loniceraes, 3 parts of Radix Angelicae Sinensis, 14 parts of Fructus Crataegis, 5 parts of Semen Plantaginiss
Preparation method, for getting above crude drug, is put into container, adds cold water and covers powder, soaks 15~20 minutes, then adds water and do not have approximately 8 centimetres of powder, is decocted.At a simmer, adopt intense fire to decoct, boil rear with slow fire boiling 20~30 minutes; Decoct for the second time the water rear slow fire boiling 15~20 minutes of boiling.Twice decoction extracting juice that removes slag, merge.
Reference substance 1
The pharmaceutical composition of the disclosed treatment cough of CN102078558A, wherein the weight proportion of crude drug is as follows: 30 parts of Ramulus Uncariae Cum Uncis, 40 parts of Concretio Silicea Bambusaes, 10 parts of Radix Platycodoniss; 50 parts of Fructus Amomis, 50 parts of Pericarpium Citri Reticulataes, 10 parts, Poria; 50 parts of Herba Menthaes, 20 parts, Radix Glycyrrhizae, 7 parts of Calculus Boviss.
Reference substance 2
The Chinese medicine preparation of the disclosed treatment cold cough of CN101991802A, it contains 30 parts of Flos Loniceraes, 30 parts of Pericarpium Citri Reticulataes, 25 parts of Herba Artemisiae Scopariaes, 35 parts of the Radixs Stemonae, 30 parts, Radix Glycyrrhizae, 25 parts of Semen Armeniacae Amarums, 25 parts of Semen Platycladi, 20 parts of Bulbus Fritillariae Uninbracteataes, 30 parts of Radix Platycodoniss, 20 parts, Fructus Jujubae, 15 parts, dry moxa leaf and appropriate Mel.
Experimental example 2: the antitussive effect that sulfur dioxide smog is caused to mouse cough model
The mice of 18-22 g is divided into to 5 groups at random, model control group gives the gavage normal saline, tested group gives gavage embodiment 1 and each 2.0 g/kg of reference substance 1,2 described drug samples, positive controls gives Fructus Chebulae's soup extract 2.0 g/kg, the gavage volume is about 1 ml/100 g, successive administration 5 days.After the last administration 30 minutes, mice is put in airtight glass box, quantitatively spraying into smog that sulfur burning generates induces to cause and coughs, record in mouse cough incubation period and 3 minutes the number of times of coughing, tested group of embodiment 1 of result and the average cough latent period of positive drug control group all extend more than 30 seconds, the number of times of on average coughing obviously reduces, tested group of average cough latent period of reference substance 1,2 all extends more than 10 seconds, the number of times of on average coughing is more, show that drug sample of the present invention has obvious antitussive effect, be better than Fructus Chebulae's sweet Fructus Citri tangerinae soup extract and reference substance 1,2.Experimental result is as shown in table 1.
Table 1 drug sample of the present invention to sulfur dioxide smog cause mouse cough antitussive effect (
Figure 112068DEST_PATH_IMAGE001
± S, n=15)
Figure 891805DEST_PATH_IMAGE002
Annotate: compare * with model group p<0.05, * * p<0.01
Embodiment 3 clinical therapeutic efficacies:
Criterion of therapeutical effect: curative effect judges whether Main Basis disappears for the cough symptom.Medication 15 days is 1 course for the treatment of.Concrete curative effect is divided following three grades: cure---and the cough symptom all disappears; Taking a turn for the better---the cough symptom obviously alleviates; Invalid---after medication 1 course for the treatment of, the cough symptom has no to disappear.
Effect: by Drug therapy cough patient of the present invention 44 examples, treat 1 course for the treatment of, wherein cure 43 examples, 1 example that takes a turn for the better, cure rate is 97.7%, effective percentage is 100%.
Model case:
Grandson, female, 67 years old, peasant.In November, 2006 is medical.Patient's readme, criminal's cough is existing has a surplus on the 10th.The symptom cough is breathed hard, coughs up phlegm sticky yellow, and pharyngalgia, micro evil wind is cold.White and thin fur, red tip of the tongue, floating and rapid pulse.Adopt medicine of the present invention, first take 10 days, symptom is clearly better, and follow-uply takes 5 days, recovery from illness.Within 2 months, visit, have no recurrence.

Claims (1)

1. a Chinese medicine composition that is used for the treatment of cough, wherein the weight proportion of crude drug is approximately as follows:
17 parts of Bulbus Liliies, 14 parts of Herba Houttuyniae, 15 parts, Semen Persicae, 17 parts, Radix Glycyrrhizae, 16 parts of Fructus Forsythiaes, 12 parts, Semen Armeniacae Amarum, 14 parts, Poria, 9 parts of Radix Ophiopogonis, 13 parts of Radix Adenophorae (Radix Glehniae), 14 parts of the Rhizoma Anemarrhenaes, 11 parts of Semen Platycladi, 13 parts of Bulbus Fritillariae Uninbracteataes, 17 parts of Radix Platycodoniss, 10 parts of Radix Scutellariaes, 15 parts of Herba Menthaes, 14 parts of the Radixs Stemonae, 16 parts of Flos Loniceraes, 3 parts of Radix Angelicae Sinensis, 14 parts of Fructus Crataegis, 5 parts of Semen Plantaginiss.
CN201310343468.6A 2013-08-08 2013-08-08 Traditional Chinese medicine composition for treating cough Active CN103432490B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310343468.6A CN103432490B (en) 2013-08-08 2013-08-08 Traditional Chinese medicine composition for treating cough

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310343468.6A CN103432490B (en) 2013-08-08 2013-08-08 Traditional Chinese medicine composition for treating cough

Publications (2)

Publication Number Publication Date
CN103432490A true CN103432490A (en) 2013-12-11
CN103432490B CN103432490B (en) 2015-02-25

Family

ID=49686274

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310343468.6A Active CN103432490B (en) 2013-08-08 2013-08-08 Traditional Chinese medicine composition for treating cough

Country Status (1)

Country Link
CN (1) CN103432490B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105106899A (en) * 2015-09-21 2015-12-02 董春年 Traditional Chinese medicine preparation for treating cough

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770526A (en) * 2016-03-15 2016-07-20 张向萍 Lung clearing decoction

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101991802A (en) * 2009-08-17 2011-03-30 王琼 Chinese materia medica preparation for treating cold and cough
CN102078558A (en) * 2009-11-27 2011-06-01 龙毅 Pharmaceutical composition for treating cough and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101991802A (en) * 2009-08-17 2011-03-30 王琼 Chinese materia medica preparation for treating cold and cough
CN102078558A (en) * 2009-11-27 2011-06-01 龙毅 Pharmaceutical composition for treating cough and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
李雪琳: "自拟止咳清肺汤加减治疗咳嗽150例", 《云南中医中药杂志》, vol. 33, no. 3, 31 December 2012 (2012-12-31), pages 41 - 42 *
黄爽明等: "浅谈治咳"十法"在咳嗽治疗中的应用", 《甘肃中医》, vol. 21, no. 3, 31 December 2008 (2008-12-31), pages 40 - 42 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105106899A (en) * 2015-09-21 2015-12-02 董春年 Traditional Chinese medicine preparation for treating cough

Also Published As

Publication number Publication date
CN103432490B (en) 2015-02-25

Similar Documents

Publication Publication Date Title
CN102631610B (en) Chinese herb for treating pediatric chronic cough
CN102430072B (en) Traditional Chinese medicine composite for treating cough
CN102872381B (en) Traditional Chinese medicine composition for treating epidemic parotitis
CN104257704A (en) Novel application of eurycoma longifolia extracts
CN104587298A (en) Traditional Chinese medicinal composition for treating pulmonary abscess
CN103394004B (en) Composition used for treating cough
CN103394020B (en) Composition used for treating cough
CN103394007B (en) Traditional Chinese medicine composition used for treating cough
CN103393944B (en) Traditional Chinese medicine used for treating cough
CN103656122B (en) Chinese medicine for the treatment of fever caused by exogenous pathogenic factors and preparation method thereof
CN104771658A (en) Traditional Chinese medicine composition for treating cough
CN103432490B (en) Traditional Chinese medicine composition for treating cough
CN103961614A (en) Traditional Chinese medicine composition for treating respiratory system diseases as well as preparation method and application thereof
CN103446519B (en) Traditional Chinese medicine composition for treating cough
CN103432491B (en) Pharmaceutical composition
CN103394005B (en) Traditional Chinese medicine composition used for treating cough
CN103463535B (en) Cough treatment traditional Chinese medicine composition
CN104435567A (en) Traditional Chinese medicinal composition containing gynostemma pentaphyllum for treating gout
CN104383486A (en) Medicament for treating bronchitis of children
CN103341063A (en) Chinese medicine composition for treating wind-heat cough
CN103550642B (en) A kind of Chinese medicine composition for the treatment of wind-warm lung-heat disease caused by wind-heat invading the lung
CN103394006B (en) Traditional Chinese medicine composition
CN103432489B (en) Pharmaceutical composition containing dextromethorphan hydrobromide
CN103446518B (en) Pharmaceutical composition containing dextromethorphan hydrobromide
CN103877169B (en) A kind of compositions for the treatment of cough

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20230104

Address after: No. 168, Jinshan Road, Luoxi Street, Linyi Hi tech Industrial Development Zone, Shandong 276000

Patentee after: Shandong Runmeng Emergency Rescue Equipment Co.,Ltd.

Address before: No. 8, Yingbin Road, Software Park, Development Zone, Hai'an County, Jiangsu Province 226600

Patentee before: HAIAN CHANGZHOU UNIVERSITY TECHNOLOGY TRANSFER CENTER Co.,Ltd.

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20230823

Address after: Room 4014, No. 258 Fulin Road, Hengqin New District, Zhuhai City, Guangdong Province, 519031

Patentee after: Zhuhai Hengqin Maikairui Pharmaceutical Technology Co.,Ltd.

Address before: No. 168, Jinshan Road, Luoxi Street, Linyi Hi tech Industrial Development Zone, Shandong 276000

Patentee before: Shandong Runmeng Emergency Rescue Equipment Co.,Ltd.