CN103432476A - Composition consisting of effective traditional Chinese medicine parts and used for treating hyperthyroidism - Google Patents
Composition consisting of effective traditional Chinese medicine parts and used for treating hyperthyroidism Download PDFInfo
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- CN103432476A CN103432476A CN2013103582033A CN201310358203A CN103432476A CN 103432476 A CN103432476 A CN 103432476A CN 2013103582033 A CN2013103582033 A CN 2013103582033A CN 201310358203 A CN201310358203 A CN 201310358203A CN 103432476 A CN103432476 A CN 103432476A
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- hyperthyroidism
- chinese medicinal
- part composition
- medicinal effective
- composition
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Links
- 239000000203 mixture Substances 0.000 title claims abstract description 21
- 206010020850 Hyperthyroidism Diseases 0.000 title claims abstract description 19
- 239000003814 drug Substances 0.000 title claims abstract description 7
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims abstract description 4
- 235000006226 Areca catechu Nutrition 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 244000080767 Areca catechu Species 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 239000002699 waste material Substances 0.000 claims description 2
- 229940079593 drug Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 8
- 210000004185 liver Anatomy 0.000 abstract description 2
- 244000235603 Acacia catechu Species 0.000 abstract 1
- 241000512259 Ascophyllum nodosum Species 0.000 abstract 1
- 240000005717 Dioscorea alata Species 0.000 abstract 1
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 abstract 1
- 238000007599 discharging Methods 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 description 4
- 206010018498 Goitre Diseases 0.000 description 3
- 201000003872 goiter Diseases 0.000 description 3
- 210000001685 thyroid gland Anatomy 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 208000032841 Bulimia Diseases 0.000 description 1
- 206010006550 Bulimia nervosa Diseases 0.000 description 1
- 208000008454 Hyperhidrosis Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 208000001871 Tachycardia Diseases 0.000 description 1
- AUYYCJSJGJYCDS-LBPRGKRZSA-N Thyrolar Chemical class IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 AUYYCJSJGJYCDS-LBPRGKRZSA-N 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 208000030172 endocrine system disease Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000037315 hyperhidrosis Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000006794 tachycardia Effects 0.000 description 1
- 239000005495 thyroid hormone Substances 0.000 description 1
- 229940036555 thyroid hormone Drugs 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a composition consisting of effective traditional Chinese medicine parts and used for treating hyperthyroidism. The composition is prepared from the raw materials of dens draconis, airpotato yam rhizome, kelp, catechu, malt, radix achyranthis bidentatae according to certain parts by weight. The composition has the effects of soothing liver, relieving depression, discharging fire, relieving stagnant qi, softening hard lumps, dispelling nodes, nourishing yin and lessening fire. The composition has a remarkable curative effect in treating hyperthyroidism, is free from side effect, and is high in safety.
Description
Technical field
The present invention relates to the Chinese medicine composition field, be specifically related to a kind of Chinese medicinal effective-part composition that is used for the treatment of hyperthyroidism.
Background technology
Hyperthyroidism, be called for short hyperthyroidism, is because a kind of common endocrinopathy of thyroid hormone secretion due to too much.Clinical take thyromegaly, bulimia, lose weight, the symptom such as tachycardia, emotion are easy to excitement, To Be Protected from Heat hyperhidrosis, hands are trembled, expophthalmos is as main.Common with the women, its sickness rate is very high.Growth trend is seemingly arranged in recent years, its definite etiology unknown.Modern western medicine has certain limitation in treatment, and can produce untoward reaction and side effect.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicinal effective-part composition for the preparation of the treatment hyperthyroidism, this active component composition can be treated hyperthyroidism, and is difficult for recurrence.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The traditional Chinese medical science thinks that the primary disease cause of disease is mainly that feelings will internal injury, physical factors, diet and water and soil are inappropriate.And stagnation of QI due to depression of the liver, QI-blood circulation is not normal, the phlegm-damp cohesion, and stopping up the knot throat is the hyperthyroidism basic pathogenesis.How real this onset of disease is, and how empty prolonged illness is.
A kind of Chinese medicinal effective-part composition for the treatment of hyperthyroidism, by making according to the raw material of mass fraction meter as follows: Dens Draconis 28, Rhizoma Dioscoreae Bulbiferae 23, Thallus Laminariae (Thallus Eckloniae) 20, catechu 15, Fructus Hordei Germinatus 8 and Radix Achyranthis Bidentatae 6.
The preparation method of Chinese medicinal effective-part composition of the present invention be by the above-mentioned raw materials compositions according to the proportioning combination drying, add 18 times of water gagings, boil with high heat, change slow fire boiling into 2 hours, waste, obtain.
Compared with prior art, the present invention has following beneficial effect:
Through experiment, find, the Chinese medicinal effective-part composition of making according to proportioning of the present invention has the effect of dispersing the stagnated live-QI to relieve the stagnation of QI, pathogenic fire purging dispelling the stagnated QI, hard masses softening and resolving, nourishing YIN to lower pathogenic fire, can be used for the treatment of hyperthyroidism, after curing, is difficult for recurrence.
The specific embodiment
Further explain the present invention below in conjunction with embodiment, but embodiment does not limit in any form to the present invention.
embodiment 1
Dens Draconis 28g, Rhizoma Dioscoreae Bulbiferae 23g, Thallus Laminariae (Thallus Eckloniae) 20g, catechu 15g, Fructus Hordei Germinatus 8g and Radix Achyranthis Bidentatae 6g, add 18 times of water gagings after drying, after boiling with intense fire, then use slow fire decocting 120min, and the gained decoction is standby.
embodiment 2
500 of clinical observation patients with hyperthyroidisms.The patient all is diagnosed as hyperthyroidism through clinical diagnosis.Take embodiment 1 gained decoction to the patient, 2 times on the 1st, sooner or later bfore meals, continuous 15 days.
Take patient's statistical result of embodiment 1 gained decoction in Table 1.Produce effects in table 1 comprises cures and effectively, wherein, cures and refers to that clinical symptom disappearance, goiter, expophthalmos and relevant sign recover normally substantially, and thyroid function is recovered normally; Effectively refer to that clinical symptoms disappears substantially, goiter, expophthalmos and relevant body weight obviously alleviate, and the thyroid function inspection approaches normal.Invalidly refer to that clinical symptoms and sign are without improvement, T3 and T4 are unchanged, and thyroid function checks without changing.
Table 1
| Number of cases | Produce effects | Invalid | Obvious effective rate (%) |
| 500 | 476 | 24 | 95.2 |
Known by above-mentioned data, after Chinese medicine of the present invention is made decoction, can be in 15 days the treatment hyperthyroidism of highly significant.
embodiment 3
The decoction administration ICR mice of using embodiment 1 to make, body weight 20 ~ 25g, male and female half and half, successive administration 60d.
Through prerun, the decoction toxicity that embodiment 1 makes is very low, does not measure LD50, therefore mice is carried out to maximum dosage-feeding on the one, measures.Maximum dosage-feeding is 400ml/d, observes none example after 60 days and is poisoned to death, and all healthy survival, prove that the decoction that compositions of the present invention is made can toxic side effect to human body thus.
Claims (4)
1. a Chinese medicinal effective-part composition for the treatment of hyperthyroidism, is characterized in that by making according to the raw material of mass fraction meter as follows: Dens Draconis 28, Rhizoma Dioscoreae Bulbiferae 23, Thallus Laminariae (Thallus Eckloniae) 20, catechu 15, Fructus Hordei Germinatus 8 and Radix Achyranthis Bidentatae 6.
2. the Chinese medicinal effective-part composition for the treatment of hyperthyroidism according to claim 1, is characterized in that described Chinese medicinal effective-part composition makes decoction.
3. the preparation method of the Chinese medicinal effective-part composition of the described treatment hyperthyroidism of claim 1 or 2, is characterized in that each crude drug adding 18 times of water gagings according to the proportioning combination drying, boil with high heat, change slow fire boiling into 2 hours, waste, obtain.
4. the application of claim 1 or 2 described Chinese medicinal effective-part composition, is characterized in that the medicine of described Chinese medicinal effective-part composition for the preparation of the treatment hyperthyroidism.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310358203.3A CN103432476B (en) | 2013-08-17 | 2013-08-17 | Composition consisting of effective traditional Chinese medicine parts and used for treating hyperthyroidism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310358203.3A CN103432476B (en) | 2013-08-17 | 2013-08-17 | Composition consisting of effective traditional Chinese medicine parts and used for treating hyperthyroidism |
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| Publication Number | Publication Date |
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| CN103432476A true CN103432476A (en) | 2013-12-11 |
| CN103432476B CN103432476B (en) | 2015-04-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310358203.3A Expired - Fee Related CN103432476B (en) | 2013-08-17 | 2013-08-17 | Composition consisting of effective traditional Chinese medicine parts and used for treating hyperthyroidism |
Country Status (1)
| Country | Link |
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| CN (1) | CN103432476B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213799A (en) * | 2015-11-02 | 2016-01-06 | 李留娟 | A kind of Chinese medicine preparation and preparation method for the treatment of the hyperthyroidism of phlegm stagnation fire type |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1781536A (en) * | 2005-09-22 | 2006-06-07 | 刘文龙 | Chinese medicine compound preparation for treating hyperthyoidism |
| CN101152399A (en) * | 2007-09-15 | 2008-04-02 | 尹克华 | Traditional Chinese medicine for treating goiter |
| CN101152422A (en) * | 2007-09-24 | 2008-04-02 | 王官远 | Paralysis-removing anti-cancer wine for treating thyroid cancer |
| CN101288759A (en) * | 2008-05-15 | 2008-10-22 | 天科仁祥技术（北京）有限责任公司 | Chinese medicinal composition for treating benign thyroid tumor and its preparation method |
| CN101757370A (en) * | 2009-11-16 | 2010-06-30 | 山西省屯留县科技情报服务中心 | Medication for treating thyroiditis and preparation method thereof |
| CN102283981A (en) * | 2011-09-13 | 2011-12-21 | 潞城市振鑫农牧专业合作社 | Drug for curing hyperthyroidism and preparation method thereof |
| CN102698043A (en) * | 2012-05-28 | 2012-10-03 | 孙立平 | Medicinal combination for treating thyroid gland |
-
2013
- 2013-08-17 CN CN201310358203.3A patent/CN103432476B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1781536A (en) * | 2005-09-22 | 2006-06-07 | 刘文龙 | Chinese medicine compound preparation for treating hyperthyoidism |
| CN101152399A (en) * | 2007-09-15 | 2008-04-02 | 尹克华 | Traditional Chinese medicine for treating goiter |
| CN101152422A (en) * | 2007-09-24 | 2008-04-02 | 王官远 | Paralysis-removing anti-cancer wine for treating thyroid cancer |
| CN101288759A (en) * | 2008-05-15 | 2008-10-22 | 天科仁祥技术（北京）有限责任公司 | Chinese medicinal composition for treating benign thyroid tumor and its preparation method |
| CN101757370A (en) * | 2009-11-16 | 2010-06-30 | 山西省屯留县科技情报服务中心 | Medication for treating thyroiditis and preparation method thereof |
| CN102283981A (en) * | 2011-09-13 | 2011-12-21 | 潞城市振鑫农牧专业合作社 | Drug for curing hyperthyroidism and preparation method thereof |
| CN102698043A (en) * | 2012-05-28 | 2012-10-03 | 孙立平 | Medicinal combination for treating thyroid gland |
Non-Patent Citations (4)
| Title |
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| 张笑平: "毒性弥漫性甲状腺肿的中医诊治", 《中国临床医生》 * |
| 李雨泽等: "张瑞林教授治疗甲状腺疾病的经验", 《中医药导报》 * |
| 钱彦方: "甲状腺病中医论治体会", 《中华中医药学刊》 * |
| 黄小敏: "甲状腺机能亢进症的国家级名中医辨治规律初探", 《广州中医药大学》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213799A (en) * | 2015-11-02 | 2016-01-06 | 李留娟 | A kind of Chinese medicine preparation and preparation method for the treatment of the hyperthyroidism of phlegm stagnation fire type |
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| CN103432476B (en) | 2015-04-15 |
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Owner name: ZHANG QUN Free format text: FORMER OWNER: GUANGZHOU YUNQIAO BIOTECHNOLOGY CO., LTD. Effective date: 20150226 |
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Effective date of registration: 20150226 Address after: The Eastern Development Zone of Guangzhou City, Guangdong province 510000 two Building Room 302 Xinyuan Street Chunhui Applicant after: Zhang Qun Address before: 510000, Guangzhou, Guangdong, Luogang District Province, No. 6, No. 601, Lai Lai Road Applicant before: Guangzhou Yunqiao Biological Technology Co., Ltd. |
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