CN103432307A - Traditional Chinese medicine effective part composition for treating rosacea and preparation method thereof - Google Patents
Traditional Chinese medicine effective part composition for treating rosacea and preparation method thereof Download PDFInfo
- Publication number
- CN103432307A CN103432307A CN2013103430986A CN201310343098A CN103432307A CN 103432307 A CN103432307 A CN 103432307A CN 2013103430986 A CN2013103430986 A CN 2013103430986A CN 201310343098 A CN201310343098 A CN 201310343098A CN 103432307 A CN103432307 A CN 103432307A
- Authority
- CN
- China
- Prior art keywords
- part composition
- chinese medicinal
- rosacea
- preparation
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine effective part composition for treating rosacea and a preparation method thereof. The traditional Chinese medicine effective part composition is prepared by the following raw materials in parts by weight: siraitia grosvenorii, narcissus, salvia plebeian and fenugreek. The traditional Chinese medicine effective part composition provided by the invention can be prepared into medicine for treating rosacea, and has effects of clearing lung stomach and purging heat, clearing heat and removing toxicity, and activating blood and dissolving stasis, can be used for treating rosacea obviously, and has the advantages of no toxicity or side effects, and high security.
Description
Technical field
The present invention relates to the Chinese medicine composition field, be specifically related to a kind of Chinese medicinal effective-part composition that is used for the treatment of rosacea and preparation method thereof.
Background technology
Rosacea is a kind of common skin obstinate disease, is more common in the middle age person that has the seborrhea.Although primary disease generally to health without serious harm, subjective symptoms is also slighter, because primary disease has hindered the attractive in appearance of face, brings misery and worry psychologically often to the patient.Modern western medicine still lacks the radical cure method, generally adopts anti-inflammation, calmness, supplements the method treatments such as vitamin B group, and uncertain therapeutic efficacy is cut, easily recurrence.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicinal effective-part composition for the preparation of the treatment rosacea, this Chinese medicinal effective-part composition can be treated rosacea fast and effectively, has advantages of that therapeutic effect is remarkable, safe, has no side effect.
Another purpose of the present invention is to provide the preparation method of above-mentioned Chinese medicinal effective-part composition.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The cause of disease of rosacea is many to be caused because of eating and drinking without temperance and the exterior tightened by pathogenic windcold.Its pathological change can be summarized as retention of heat in the spleen and stomach, lung meridian accumulated heat and three aspects of cold blood stasis.
The Chinese medicinal effective-part composition for the treatment of rosacea of the present invention is by making according to the raw material of mass fraction meter as follows: Fructus Momordicae 30, narcissus 8, Herba Salviae Plebeiae 25, Fluoritum 6 and Semen Trigonellae 31.
The dosage form that the present invention treats the applicable processing of Chinese medicinal effective-part composition of rosacea is oral liquid.
The preparation method of the Chinese medicinal effective-part composition for the treatment of rosacea of the present invention comprises the steps:
(1) each Chinese medicinal components is pulverized, added 12 times of water gagings, decoct 3 times, decoct 1 hour at every turn; Merging filtrate after the filtration decocting liquid, be evaporated to the cream that relative concentration is 1.14, adds ethanol, and making it contain the alcohol amount is 69%, and standing over night, reclaim ethanol, concentrated;
(2) concentrated solution after concentrating is added to applicable adjuvant according to conventional formulation technique, the processing oral liquid.
Compared with prior art, the present invention has following beneficial effect:
(1) compositions of the present invention has the effect of come down in torrents lung stomach accumulated heat, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, through test, and can the fast treating rosacea.
(2) present composition has no side effect.
(3) preparation method of the present composition is simple, and yield is high, has effectively kept the effective ingredient of medicine.
The specific embodiment
Further explain the present invention below in conjunction with embodiment, but embodiment does not limit in any form to the present invention.
embodiment 1
Get Fructus Momordicae 30g, narcissus 8g, Herba Salviae Plebeiae 25g, Fluoritum 6g and Semen Trigonellae 31g, be crushed to coarse powder, add 12 times of water gagings, decoct 3 times, decoct 1 hour at every turn; Merging filtrate after the filtration decocting liquid, be evaporated to the cream that relative concentration is 1.14, adds ethanol, making it contain the alcohol amount is 69%, and standing over night, reclaim ethanol, obtain concentrated solution 1000ml, get simple syrup, add above-mentioned concentrated solution, and adjust pH to 4 with citric acid, adding distil water is to 5000ml, stir, be distributed into after fine straining in the 15ml vial, be packaged to be oral liquid.
This product is the yellowish-brown clear liquid, places in half a year and does not produce muddiness, and pH approximately 4, total solid 9% left and right.
embodiment 2
Clinical observation patient 100 examples, patient all has obvious rosacea clinical symptoms and makes a definite diagnosis through the clinicist.
The oral liquid that oral embodiment 1 makes, every day 2 times, each 15ml.Administration time is 10 days.
After 10 days, use patient's statistical result of embodiment 1 gained oral liquid in Table 1.
Criterion of therapeutical effect: produce effects comprises recovery from illness and takes a turn for the better, wherein, fully recovers and refers to that erythra (as erythema, pimple, pustule etc.) disappears fully, and the subjective symptoms disappearance, it is normal that skin color recovers, without newly rash appearance; Improvement refers to that deflorescence is more than 70%, and new rash occurs less, and flushing goes down.Skin still has slight erythema, or the little pimple of minority.Invalidly refer to that symptom is without improvement, even aggravation, flushing still, still has new rash to occur, sometimes has concurrently and oozes out, pain and swelling.
Table 1
| Number of cases | Produce effects | Invalid | Obvious effective rate (%) |
| 100 | 99 | 1 | 99 |
Known by table 1, the oral liquid that embodiment 1 obtains has specially good effect at the treatment rosacea.After Chinese medicine of the present invention is made oral liquid, can be in 10 days highly significant healing or alleviate the rosacea disease.
embodiment 3
The oral liquid administration ICR mice of using embodiment 1 to make, body weight 20 ~ 25g, male and female half and half, successive administration 90d.
Through prerun, the lotion toxicity that embodiment 1 makes is very low, does not measure LD50, therefore mice is carried out to maximum dosage-feeding on the one, measures.Maximum dosage-feeding is 150ml/d, observes none example after 90 days and is poisoned to death, and all healthy survival, prove that the oral liquid that compositions of the present invention is made can not cause toxic and side effects to human body thus.
Claims (4)
1. a Chinese medicinal effective-part composition for the treatment of rosacea, is characterized in that by making according to the raw material of mass fraction meter as follows: Fructus Momordicae 30, narcissus 8, Herba Salviae Plebeiae 25, Fluoritum 6 and Semen Trigonellae 31.
2. the Chinese medicinal effective-part composition for the treatment of rosacea according to claim 1, is characterized in that described Chinese medicine composition makes oral liquid.
3. the preparation method of the Chinese medicinal effective-part composition of the described treatment rosacea of claim 1 or 2, is characterized in that comprising the steps:
(1) each Chinese medicinal components is pulverized, added 12 times of water gagings, decoct 3 times, decoct 1 hour at every turn; Merging filtrate after the filtration decocting liquid, be evaporated to the cream that relative concentration is 1.14, adds ethanol, and making it contain the alcohol amount is 69%, and standing over night, reclaim ethanol, concentrated;
(2) concentrated solution after concentrating is added to applicable adjuvant according to conventional formulation technique, the processing oral liquid.
4. the application of claim 1 or 2 described Chinese medicinal effective-part composition, is characterized in that the medicine of described Chinese medicinal effective-part composition for the preparation of the treatment rosacea.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013103430986A CN103432307A (en) | 2013-08-08 | 2013-08-08 | Traditional Chinese medicine effective part composition for treating rosacea and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013103430986A CN103432307A (en) | 2013-08-08 | 2013-08-08 | Traditional Chinese medicine effective part composition for treating rosacea and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103432307A true CN103432307A (en) | 2013-12-11 |
Family
ID=49686092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2013103430986A Pending CN103432307A (en) | 2013-08-08 | 2013-08-08 | Traditional Chinese medicine effective part composition for treating rosacea and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103432307A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101491653A (en) * | 2008-01-23 | 2009-07-29 | 郑州大学 | Traditional Chinese medicine composite for treating rosacea and use method thereof |
-
2013
- 2013-08-08 CN CN2013103430986A patent/CN103432307A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101491653A (en) * | 2008-01-23 | 2009-07-29 | 郑州大学 | Traditional Chinese medicine composite for treating rosacea and use method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 张传书；等: "误食水仙苗中毒三例报告", 《山西中医》, no. 1, 31 December 1990 (1990-12-31), pages 40 * |
| 张翠月；等: "中药内外合治酒渣鼻36例", 《中医杂志》, vol. 52, no. 17, 30 September 2011 (2011-09-30), pages 1504 - 1505 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103463539A (en) | Drug for treating eczema, and preparation method and use thereof | |
| CN102319397A (en) | Chinese medicinal decoction for treating chronic pelvic inflammatory disease with clystering method | |
| CN109620879A (en) | A kind of wet repairing paste and preparation method thereof clearly | |
| CN101181383A (en) | Medicine composition for treating apoplexy as well as preparation method | |
| CN103638204B (en) | A kind of Chinese medicine composition for the treatment of eczema | |
| CN103417815A (en) | Traditional Chinese medicine effective part composition for treating hemorrhagic stroke, and preparation method of same | |
| CN103610795A (en) | Method for preparing eucommia ulmoides step-down oral preparation | |
| CN103550744B (en) | A kind of pure Chinese medicinal preparation for oral ulcer | |
| CN102552560B (en) | Compound combination medicament for effectively treating hand-foot-and-mouth disease | |
| CN103239646B (en) | Chinese medicine effective part composition for treating leucoderma and preparation method thereof | |
| CN103239605B (en) | Chinese medicine effective part composition for treating hyperostosis and preparation method of Chinese medicine effective part composition | |
| CN103432307A (en) | Traditional Chinese medicine effective part composition for treating rosacea and preparation method thereof | |
| CN103239543B (en) | Chinese medicine effective part composition for treating gastroptosis and preparation method of Chinese medicine effective part composition | |
| CN103432247B (en) | Traditional Chinese medicine effective part composition for treating ischemic stroke and preparation method thereof | |
| CN103432204B (en) | Traditional Chinese medicine effective part composition for treating schizophrenia and preparation method thereof | |
| CN104055959A (en) | Traditional Chinese medicine lotion and nursing method for treating gastrointestinal dampness-heat type seborrhoeic dermatitis | |
| CN103239564B (en) | Chinese medicine effective part composition for treating chronic nephritis and preparation method of Chinese medicine effective part composition | |
| CN102772762B (en) | Traditional Chinese medicinal active ingredient composition for treating skin diseases and method for preparing traditional Chinese medicinal active ingredient composition | |
| CN103239671B (en) | Chinese medicine effective part composition for treating climacteric syndrome and preparation method of Chinese medicine effective part composition | |
| CN103239571B (en) | Chinese medicine effective part composition for treating alopecia areata and preparation method thereof | |
| CN103463170B (en) | Hyperosteogeny treatment traditional Chinese medicine effective fraction composition and preparation method thereof | |
| CN104225343A (en) | Chinese herbal preparation for treating urinary tract infection and preparation method thereof | |
| CN104435491A (en) | Effective part composition of traditional Chinese medicine for treating parkinson disease and preparation method of effective part composition | |
| CN103565986A (en) | Chinese medicine active part composition for treating Reynolds disease and preparation method thereof | |
| CN103417900B (en) | Composition of effective part of traditional Chinese medicine and preparation method of composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20131211 |