CN103432253A - Chinese herbal preparation for clearing heat, reducing swelling and relieving pain, and preparation method thereof - Google Patents
Chinese herbal preparation for clearing heat, reducing swelling and relieving pain, and preparation method thereof Download PDFInfo
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Abstract
The invention provides a Chinese herbal preparation for clearing heat, reducing swelling and relieving pain, which is an external preparation. The Chinese herbal preparation comprises the following active components in parts by weight: 5-30 parts of cortex phellodendri, 2-20 parts of coptis chinensis, 5-30 parts of rheum officinale, 12-50 parts of gypsum, 2-20 parts of borneol, 12-50 parts of purslane, 12-50 parts of herba siegesbeckiae, 5-30 parts of pharbitis seeds, 5-30 parts of radix stephaniae tetrandrae, 5-30 parts of semen lagenariae sicerariae, 5-30 parts of poria peel, 5-30 parts of mirabilite, 12-50 parts of clematis roots and 12-50 parts of rhizoma corydalis. The Chinese herbal preparation is locally applied to the outside of joints, can remarkably relieve inflammation of joints, caused by trauma or rheumatism, has favorable curative effects of clearing heat, reducing swelling, smoothing veins and relieving pain, can further improve Chinese medicine symptoms (such as thirst, restlessness sweating and deep-colored urine) of dampness-heat blockage type arthritis patients, has less adverse effects, and is free from allergic eruption and blister, allergic reaction, light sensitization reaction and the like.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, relate in particular to Chinese medicine preparation of the low clearing heat for detumescence pain relieving of a kind of side effect and preparation method thereof.
Background technology
Arthritis is not only a kind of chronic disease, is also a kind of disease comparatively common in middle-aged and elderly people.Its outstanding clinical manifestation is chronic, repeatedly outbreak, that increase the weight of gradually, multiple, with joints such as hands, wrist, foots, the most often get involved, the stiff time in morning is longer, present in early days red, swollen, hot, the pain and dysfunction, late period, joint can occur that in various degree aggressivity changes and carrying out property is strong and lopsided, and bone and bones amyotrophy is arranged, be the disease that a kind of disability rate is higher.
At present the medicine for the treatment of of arthritis is divided into two kinds of for oral administration and externals, and wherein medicine for external use is owing to being directly to be coated in disease sites, and directly osmotic absorption, make its pain relieving texts good, and safer reliably, narrowed by the green grass or young crops of Most patients.But have in the market arthritic medicine for external use.Votalin Ointment (the full name: the diclofenac diethylammonium emulsifiable paste) that for example Novartis Pharma AG produces.
The main active of Votalin Ointment is the diclofenac diethylamine, every gram Votalin Ointment is containing 10 milligrams of diclofenac diethylamine (in diclofenac sodium), wherein, the diclofenac of performance drug effect belongs to NSAID (non-steroidal anti-inflammatory drug), there is antiinflammatory, analgesia and refrigeration function, its analgesia, antiinflammatory and refrigeration function are stronger 2～2.5 times than indomethacin, stronger 26～50 times than aspirin.Main mechanism is to suppress prostaglandin synthetase, and the prostaglandin biosynthesis is obstructed.The pain caused for rheumatic arthritis, ankylosing spondylitis, non-inflammatory arthralgia, arthritis, nonarticular rheumatism, non-joint property inflammation, generate heat due to pain and various inflammation after various neuralgias, cancer pain, wound etc.Votalin Ointment can effectively be alleviated active chronic inflammation, to the inflammation caused because of wound or rheumatism, can make it that inflammatory swelling alleviates, pain relief.But the reducing swelling and alleviating pain effect is not good enough.And use Votalin Ointment allergy or nonallergic dermatitis may occur, as pimple, skin rubefaction, edema, pruritus, phlysis, large vesicle or squama etc., indivedual patients even there will be systemic rash, anaphylactic reaction (as asthma attack, vasodilation), photo sensitive reaction etc.And the adjuvant of Votalin Ointment is isopropyl alcohol, long-term contact skin can cause xerosis cutis, chap.
Summary of the invention
The object of the invention is to overcome above-mentioned deficiency, a kind of Chinese medicine preparation of clearing heat for detumescence pain relieving is provided, obviously alleviate the arthritis caused because of wound or rheumatism, side effect is low, and untoward reaction is little.
First aspect of the present invention is to provide a kind of Chinese medicine preparation of clearing heat for detumescence pain relieving, and according to the parts by weight meter, its active component comprises:
Cortex Phellodendri 5-30 part (be preferably 8-22 part, 10-20 part more preferably, 12-18 part more preferably, such as 14 parts, 15 parts or 17 parts etc.);
Rhizoma Coptidis 2-20 part (be preferably 5-13 part, 6-12 part more preferably, 7.2-10.5 part more preferably, such as 8.2 parts, 9 parts, 9.4 parts etc.);
Radix Et Rhizoma Rhei 5-30 part (be preferably 8-22 part, 10-20 part more preferably, 12-18 part more preferably, such as 14 parts, 15 parts or 17 parts etc.);
Gypsum Fibrosum 12-50 part (be preferably 20-40 part, 24-36 part more preferably, more preferably 26-32 part, such as 28 parts, 30 parts, 31 parts etc.);
Borneolum Syntheticum 2-20 part (be preferably 5-15 part, 6-13 part more preferably, 8-12 part more preferably, such as 9 parts, 10 parts, 11 parts etc.);
Herba Portulacae 12-50 part (be preferably 20-40 part, 24-36 part more preferably, more preferably 26-32 part, such as 28 parts, 30 parts, 31 parts etc.);
Herba Siegesbeckiae 12-50 part (be preferably 20-40 part, 24-36 part more preferably, more preferably 26-32 part, such as 28 parts, 30 parts, 31 parts etc.);
Semen Pharbitidis 5-30 part (be preferably 8-22 part, 10-20 part more preferably, 12-18 part more preferably, such as 14 parts, 15 parts or 17 parts etc.);
Radix Stephaniae Tetrandrae 5-30 part (be preferably 8-22 part, 10-20 part more preferably, 12-18 part more preferably, such as 14 parts, 15 parts or 17 parts etc.);
Calabash shell 5-30 part (be preferably 8-22 part, 10-20 part more preferably, 12-18 part more preferably, such as 14 parts, 15 parts or 17 parts etc.);
Cortex Sclerotii Poriae 5-30 part (be preferably 8-22 part, 10-20 part more preferably, 12-18 part more preferably, such as 14 parts, 15 parts or 17 parts etc.);
Natrii Sulfas 5-30 part (be preferably 8-22 part, 10-20 part more preferably, 12-18 part more preferably, such as 14 parts, 15 parts or 17 parts etc.);
Radix Clematidis 12-50 part (be preferably 20-40 part, 24-36 part more preferably, more preferably 26-32 part, such as 28 parts, 30 parts, 31 parts etc.);
Rhizoma corydalis 12-50 part (be preferably 20-40 part, 24-36 part more preferably, more preferably 26-32 part, such as 28 parts, 30 parts, 31 parts etc.).
Preferably, the active component of described Chinese medicine preparation is Powdered, powder particle >=50 orders.
Preferably, described powder particle >=80 orders, more preferably >=100 orders, more preferably >=200 orders, for example 300-1000 order.
Preferably, described Chinese medicine preparation is external preparation.
Wherein, described external preparation can be ointment, rubber-emplastrum, plaster, patch, gel, membrane, aerosol, cataplasma, tincture or spray etc.。
Preferably, described external preparation, except active component, also comprises substrate.
Preferably, described unguentum comprises substrate 1000-2000 part, 1200-1800 part more preferably, and 1400-1600 part more preferably, such as 1450 parts, 1500 parts, 1520 parts etc.
Substrate commonly used is one or more the mixture in vaseline, liquid Paraffin, lanoline, Cera Flava, animal oil, vegetable oil, single stearic acid glyceride, octadecanol etc.
The substrate that plaster is commonly used is vegetable oil and Plumbum preparatium, vegetable oil and hydrocerussitum, resin (Colophonium) etc.
Rubber plaster be take rubber as main matrix, rubber and resin, fat or quasi-lipid substance (adjuvant) can also be mixed as substrate.
The active component of described Chinese medicine preparation can also be dispersed in water, make suspending agent.
Also comprise auxiliary agent, described auxiliary agent comprises antiseptic, rectify and to smell one or more in agent, thickening agent, wetting agent, penetrating agent, suspending agent etc.
Described Chinese medicine preparation is preferably patch, and described patch, except active component and substrate, also comprises the film material.
The composite of described film material for consisting of high-intensity fabric substrate and polymer coating, coating shields to base material, and forms the sealing property of membrane material.
Described fabric substrate can be fabric or the non-woven of following one or more materials formations, and is preferably fabric: natural fiber, polyolefine fiber, polyester fiber, polyurethane fibre, Fypro, cotton fiber etc.
Described polymer coating consists of following one or more materials: polrvinyl chloride, polyvinyl dichloride, polyolefin (as ethylene-ethyl acetate copolymer, polyethylene and polypropylene etc.), polyurea based polyester (as polyethylene terephthalate).
Second invention of the present invention is to provide a kind of preparation method of above-mentioned Chinese medicine preparation, and described preparation method comprises the following steps:
Step 1, the ratio according to each active component in Chinese medicine preparation, take active component, mixes, and pulverizes, and sieves, and obtains Traditional Chinese drug mixture;
Step 2, make Chinese medicine preparation by described Traditional Chinese drug mixture.
Preferably, described step 2 is: in proportion substrate and Traditional Chinese drug mixture are mixed, make externally used paste.
More preferably, in the active component of described substrate after joining step 1 and processing before, first heating.
The Chinese medicine preparation of clearing heat for detumescence pain relieving provided by the invention, outside local joint, be coated with, can obviously alleviate the arthritis caused because of wound or rheumatism, there is good clearing heat for detumescence, removing obstruction in the collateral to relieve pain curative effect, and can further improve damp-heat arthralgia resistance type arthritic's traditional Chinese medical science disease (as thirsty, vexed sweating, yellow urine etc.), and its untoward reaction is little, do not find allergic rash, vesicle, without anaphylactic reaction, photo sensitive reaction etc. yet.
The specific embodiment
The active component of the Chinese medicine preparation of clearing heat for detumescence pain relieving provided by the invention comprises Cortex Phellodendri, Rhizoma Coptidis, Radix Et Rhizoma Rhei, Gypsum Fibrosum, Borneolum Syntheticum, Herba Portulacae, Herba Siegesbeckiae, Semen Pharbitidis, Radix Stephaniae Tetrandrae, calabash shell, Cortex Sclerotii Poriae, Natrii Sulfas, Radix Clematidis and rhizoma corydalis, wherein, but Herba Siegesbeckiae, Herba Portulacae expelling wind and removing dampness, dredge the meridian passage, heat-clearing and toxic substances removing, Radix Stephaniae Tetrandrae has the merit of wind-damp dispelling pain relieving, inducing diuresis to remove edema, three medicines share energy expelling wind-damp and clearing heat, reducing swelling and alleviating pain, are monarch drug altogether.Cortex Phellodendri, Rhizoma Coptidis, Gypsum Fibrosum, Radix Clematidis, calabash shell, Cortex Sclerotii Poriae, Semen Pharbitidis seven flavor medicine are minister, help monarch with heat-clearing and toxic substances removing, dehumidifying detumescence, make pathogenic heat self-defence gas and separate; Radix Et Rhizoma Rhei, Natrii Sulfas, Rhizoma Corydalis blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain are adjuvant drug altogether; The hot cold nature of Borneolum Syntheticum bitter in the mouth, hot perfume (or spice) reaches thoroughly, and assistant makes all medicines.The merit of the local pyretic toxicity of removing summer-heat, inducing diuresis to remove edema pain relieving is gathered in the combination of each active component altogether.
Below in conjunction with specific embodiment, the present invention is further illustrated, to understand better the present invention.
Embodiment 1
The Chinese medicine preparation of the clearing heat for detumescence pain relieving that the present embodiment provides is externally used paste, is prepared as follows:
Take Cortex Phellodendri 15g, Rhizoma Coptidis 9g, Radix Et Rhizoma Rhei 15g, Gypsum Fibrosum 30g, Borneolum Syntheticum 10g, Herba Portulacae 30g, Herba Siegesbeckiae 30g, Semen Pharbitidis 15g, Radix Stephaniae Tetrandrae 15g, calabash shell 15g, Cortex Sclerotii Poriae 15g, Natrii Sulfas 15g, Radix Clematidis 30g, rhizoma corydalis 30g, mixing is beaten powder and is crossed 100 mesh sieves, add and dissolve Yellow Vaselin and stir to 1500g, after condensation, obtain.
Embodiment 2
The Chinese medicine preparation of the clearing heat for detumescence pain relieving that the present embodiment provides is externally used paste, is prepared as follows:
Take Cortex Phellodendri 14g, Rhizoma Coptidis 9g, Radix Et Rhizoma Rhei 16g, Gypsum Fibrosum 28g, Borneolum Syntheticum 6g, Herba Portulacae 32g, Herba Siegesbeckiae 30g, Semen Pharbitidis 15g, Radix Stephaniae Tetrandrae 14g, calabash shell 15g, Cortex Sclerotii Poriae 16g, Natrii Sulfas 15g, Radix Clematidis 30g, rhizoma corydalis 26g, mixing is beaten powder and is crossed 100 mesh sieves, add and dissolve Yellow Vaselin and stir to 1500g, after condensation, obtain.
Embodiment 3
The Chinese medicine preparation of the clearing heat for detumescence pain relieving that the present embodiment provides is externally used paste, is prepared as follows:
Take Cortex Phellodendri 15g, Rhizoma Coptidis 10g, Radix Et Rhizoma Rhei 16g, Gypsum Fibrosum 32g, Borneolum Syntheticum 6g, Herba Portulacae 32g, Herba Siegesbeckiae 30g, Semen Pharbitidis 15g, Radix Stephaniae Tetrandrae 14g, calabash shell 15g, Cortex Sclerotii Poriae 15g, Natrii Sulfas 15g, Radix Clematidis 25g, rhizoma corydalis 25g, mixing is beaten powder and is crossed 100 mesh sieves, add and dissolve Yellow Vaselin and stir to 1500g, after condensation, obtain.
Embodiment 4
The Chinese medicine preparation of the clearing heat for detumescence pain relieving that the present embodiment provides is externally used paste, is prepared as follows:
Take Cortex Phellodendri 15g, Rhizoma Coptidis 10g, Radix Et Rhizoma Rhei 12g, Gypsum Fibrosum 30g, Borneolum Syntheticum 10g, Herba Portulacae 30g, Herba Siegesbeckiae 28g, Semen Pharbitidis 15g, Radix Stephaniae Tetrandrae 15g, calabash shell 16g, Cortex Sclerotii Poriae 15g, Natrii Sulfas 15g, Radix Clematidis 33g, rhizoma corydalis 26g, mixing is beaten powder and is crossed 100 mesh sieves, add and dissolve Yellow Vaselin and stir to 1500g, after condensation, obtain.
Embodiment 5
The Chinese medicine preparation of the clearing heat for detumescence pain relieving that the present embodiment provides is externally used paste, is prepared as follows:
Take Cortex Phellodendri 15g, Rhizoma Coptidis 10g, Radix Et Rhizoma Rhei 15g, Gypsum Fibrosum 27g, Borneolum Syntheticum 10g, Herba Portulacae 31g, Herba Siegesbeckiae 30g, Semen Pharbitidis 12g, Radix Stephaniae Tetrandrae 13g, calabash shell 15g, Cortex Sclerotii Poriae 14g, Natrii Sulfas 15g, Radix Clematidis 30g, rhizoma corydalis 29g, mixing is beaten powder and is crossed 100 mesh sieves, add and dissolve Yellow Vaselin and stir to 1500g, after condensation, obtain.
(1) pre-stage test: the Chinese medicine preparation of the clearing heat for detumescence pain relieving that adopts embodiment 1 to make carries out pre-stage test
140 routine rheumatoid arthritis (RA) are divided into to treatment group and matched group at random, carried out the comparative study of 12 weeks by a definite date, wherein, treatment group: oral methothexate, leflunomide, the Chinese medicine preparation of the clearing heat for detumescence pain relieving that external application embodiment 1 makes, matched group: matched group: oral methothexate, leflunomide.
Result shows: after treatment the 8th week and the 12nd week, treatment group ACR20(the American College of Rheumatology20, Americanism damp disease association 20% improvement standard) curative effect is better than matched group (P<0.05), and in the time of the 12nd week, the ACR50(Americanism damp disease association 20% improvement standard for the treatment of group) curative effect is better than matched group (P<0.05), shows that the Chinese medicine preparation of clearing heat for detumescence pain relieving provided by the invention truly has curative effect for damp-heat arthralgia resistance type RA.Treatment group and matched group all have significant curative effect totally alleviating and eliminate the aspects such as patient's symptom, sign, inflammatory activity indicators.Especially improving stiff time in patient morning and HAQ quality of life, reducing the swollen joint number, tenderness is closed joint number, improving the tcm syndrome aspect treatment groups such as thirsty, vexed sweating, yellow urine/red be red and all obviously be better than matched group.After treatment 12 weeks, the improvement of VAS integration is better than matched group.Two groups of tcm syndrome curative effects relatively, the total effective rate for the treatment of group is 86.96%, be better than the 76.12%(P of matched group<0.05), the Chinese medicine preparation external application that shows clearing heat for detumescence pain relieving provided by the invention except can improve local joint swollen, stiff, bitterly, the limitation of activity symptom, also have the effect of part whole body medical treatment, can improve the damp-heat arthralgia resistance syndromes such as thirsty, vexed sweating, yellow urine.Aspect drug safety, two groups irritated erythra and the common skin injury of medicine for external use do not occur, show that the Chinese medicine preparation safety of clearing heat for detumescence pain relieving provided by the invention is good.
(2) pre-stage test: the Chinese medicine preparation of the clearing heat for detumescence pain relieving that adopts embodiment 1 to make carries out pre-stage test
1) grandson, man, 67 years old.Rheumatoid arthritis 16 years, function of joint II level, III phase.The both hands proximal interphalangeal joint swell and ache number (the arthralgia number: the quantity in pain joint) 10, it is several 2 that the both hands metacarpophalangeal joints swells and ache, two carpal joint swelling and pain.DAS28: heavy.VAS scoring: 40mm.Erythrocyte sedimentation rate: 12mm/h, CRP:12.8mg/l.Give Qin Shi and disappear the external application of numbness cream after 2 weeks, it is several 0 that the both hands proximal interphalangeal joint swells and ache, and it is several 1 that the both hands metacarpophalangeal joints swells and ache, and two carpal joint swelling and pain disappear.DAS28: light.VAS scoring: 30mm.Erythrocyte sedimentation rate: 2mm/h, CRP:9.01mg/l.After applying January continuously, the discomforts such as erythra, pruritus do not appear.
2) Huang, female, 70 years old.Rheumatoid arthritis 2 years, function of joint III level, II phase.It is several 8 that the both hands proximal interphalangeal joint swells and ache, and it is several 6 that the both hands metacarpophalangeal joints swells and ache, and two carpal joint, left elbow joint swell and ache.DAS28: heavy.VAS scoring: 50mm.Erythrocyte sedimentation rate: 44mm/h, CRP:13.8mg/l.Give Qin Shi and disappear the external application of numbness cream after 2 weeks, it is several 1 that the both hands proximal interphalangeal joint swells and ache, and it is several 0 that the both hands metacarpophalangeal joints swells and ache, and left elbow joint swells and ache and alleviates, and two carpal joint swelling and pain disappear.DAS28: in.VAS scoring: 20mm.Erythrocyte sedimentation rate: 20mm/h, CRP:7.2mg/l.After applying January continuously, the discomforts such as erythra, pruritus do not appear.
3) Zhu, female, 59 years old.Rheumatoid arthritis 4 years, function of joint II level, II phase.It is several 6 that the both hands proximal interphalangeal joint swells and ache, and it is several 6 that the both hands metacarpophalangeal joints swells and ache, and two carpal joint, right elbow joint, double knee joint swell and ache.DAS28: heavy.VAS scoring: 60mm.Erythrocyte sedimentation rate: 38mm/h, CRP:11.47mg/l.Give Qin Shi and disappear the external application of numbness cream after 2 weeks, it is several 0 that the both hands proximal interphalangeal joint swells and ache, and it is several 1 that the both hands metacarpophalangeal joints swells and ache, and two carpal joint, right elbow joint swell and ache and all disappear.Double knee joint swells and ache and alleviates.DAS28: light.VAS scoring: 20mm.Erythrocyte sedimentation rate: 12mm/h, CRP:8mg/l.After applying January continuously, the discomforts such as erythra, pruritus do not appear.
In sum, the Chinese medicine preparation of clearing heat for detumescence pain relieving provided by the invention is ameliorate osteoarthritis disease significantly, have good clearing heat for detumescence, removing obstruction in the collateral to relieve pain curative effect, and untoward reaction is little.
Above specific embodiments of the invention be have been described in detail, but it is just as example, the present invention is not restricted to specific embodiment described above.To those skilled in the art, any equivalent modifications that the present invention is carried out and alternative also all among category of the present invention.Therefore, equalization conversion and the modification done without departing from the spirit and scope of the invention, all should contain within the scope of the invention.
Claims (10)
1. the Chinese medicine preparation of a clearing heat for detumescence pain relieving, it is characterized in that, according to the parts by weight meter, its active component comprises: Cortex Phellodendri 5-30 part, Rhizoma Coptidis 2-20 part, Radix Et Rhizoma Rhei 5-30 part, Gypsum Fibrosum 12-50 part, Borneolum Syntheticum 2-20 part, Herba Portulacae 12-50 Fen, Herba Siegesbeckiae 12-50 part, Semen Pharbitidis 5-30 part, Radix Stephaniae Tetrandrae 5-30 part, calabash shell 5-30 part, Cortex Sclerotii Poriae 5-30 part, Natrii Sulfas 5-30 part, Radix Clematidis 12-50 part, rhizoma corydalis 12-50 part.
2. Chinese medicine preparation according to claim 1, it is characterized in that, the active component of described Chinese medicine preparation comprises: Cortex Phellodendri 8-22 part, Rhizoma Coptidis 5-13 part, Radix Et Rhizoma Rhei 8-22 part, Gypsum Fibrosum 20-40 part, Borneolum Syntheticum 5-15 part, Herba Portulacae 20-40 Fen, Herba Siegesbeckiae 20-40 part, Semen Pharbitidis 8-22 part, Radix Stephaniae Tetrandrae 8-22 part, calabash shell 8-22 part, Cortex Sclerotii Poriae 8-22 part, Natrii Sulfas 8-22 part, Radix Clematidis 20-40 part, rhizoma corydalis 20-40 part.
3. Chinese medicine preparation according to claim 2, it is characterized in that, the active component of described Chinese medicine preparation comprises: Cortex Phellodendri 10-20 part, Rhizoma Coptidis 6-12 part, Radix Et Rhizoma Rhei 10-20 part, Gypsum Fibrosum 24-36 part, Borneolum Syntheticum 6-13 part, Herba Portulacae 24-36 Fen, Herba Siegesbeckiae 24-36 part, Semen Pharbitidis 10-20 part, Radix Stephaniae Tetrandrae 10-20 part, calabash shell 10-20 part, Cortex Sclerotii Poriae 10-20 part, Natrii Sulfas 10-20 part, Radix Clematidis 24-36 part, rhizoma corydalis 24-36 part.
4. Chinese medicine preparation according to claim 1, is characterized in that, the active component of described Chinese medicine preparation is Powdered, powder particle >=50 orders.
5. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is external preparation.
6. Chinese medicine preparation according to claim 5, is characterized in that, described external preparation is ointment, rubber-emplastrum, plaster, patch, gel, membrane, aerosol, cataplasma, tincture or spray.
7. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation, except active component, also comprises substrate.
8. Chinese medicine preparation according to claim 7, is characterized in that, described unguentum comprises substrate 1000-2000 part.
9. the preparation method of the described Chinese medicine preparation of any one in a claim 1-8, is characterized in that, described preparation method comprises the following steps:
Step 1, the ratio according to each active component in Chinese medicine preparation, take active component, mixes, and pulverizes, and sieves, and obtains Traditional Chinese drug mixture;
Step 2, make Chinese medicine preparation by described Traditional Chinese drug mixture.
10. preparation method according to claim 9, is characterized in that, described step 2 is: in proportion substrate and Traditional Chinese drug mixture are mixed, make externally used paste.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109966366A (en) * | 2019-05-17 | 2019-07-05 | 上海市光华中西医结合医院(上海市光华医院) | A kind of gel emplastrum and preparation method thereof of clearing heat for detumescence analgesic |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1433787A (en) * | 2002-01-19 | 2003-08-06 | 马献山 | Oral taken and external use medicine for antirheumatism and stopping numbness pain |
| CN102652810A (en) * | 2012-04-12 | 2012-09-05 | 王伟 | Traditional Chinese medicine composition for treating gout and preparation method of traditional Chinese medicine composition |
-
2013
- 2013-08-16 CN CN201310360885.1A patent/CN103432253B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1433787A (en) * | 2002-01-19 | 2003-08-06 | 马献山 | Oral taken and external use medicine for antirheumatism and stopping numbness pain |
| CN102652810A (en) * | 2012-04-12 | 2012-09-05 | 王伟 | Traditional Chinese medicine composition for treating gout and preparation method of traditional Chinese medicine composition |
Non-Patent Citations (2)
| Title |
|---|
| 王继东等: "消肿止痛膏配合中药透敷治疗风湿性关节炎53例", 《中医外治杂志》, vol. 14, no. 03, 30 June 2005 (2005-06-30) * |
| 赵新等: "中药泡浸对肢体功能锻炼消肿止痛效果临床研究", 《中国矫形外科杂志》, vol. 14, no. 02, 31 January 2006 (2006-01-31) * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109966366A (en) * | 2019-05-17 | 2019-07-05 | 上海市光华中西医结合医院(上海市光华医院) | A kind of gel emplastrum and preparation method thereof of clearing heat for detumescence analgesic |
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