CN103430024B - 用于免疫分析检测的系统 - Google Patents

用于免疫分析检测的系统 Download PDF

Info

Publication number
CN103430024B
CN103430024B CN201280004844.2A CN201280004844A CN103430024B CN 103430024 B CN103430024 B CN 103430024B CN 201280004844 A CN201280004844 A CN 201280004844A CN 103430024 B CN103430024 B CN 103430024B
Authority
CN
China
Prior art keywords
probe
well
wells
hole
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201280004844.2A
Other languages
English (en)
Chinese (zh)
Other versions
CN103430024A (zh
Inventor
谭洪
夏明�
谭玉山
陈骏
曹二华
李根乾
罗伯特·F·祖克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Access Medical Systems Ltd
Original Assignee
Access Medical Systems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Access Medical Systems Ltd filed Critical Access Medical Systems Ltd
Priority to CN202010094963.8A priority Critical patent/CN111505265A/zh
Priority to CN201610350276.1A priority patent/CN106018782A/zh
Publication of CN103430024A publication Critical patent/CN103430024A/zh
Application granted granted Critical
Publication of CN103430024B publication Critical patent/CN103430024B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent
    • B01L3/527Containers specially adapted for storing or dispensing a reagent for a plurality of reagents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/042Caps; Plugs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/045Connecting closures to device or container whereby the whole cover is slidable
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0429Sample carriers adapted for special purposes
    • G01N2035/0436Sample carriers adapted for special purposes with pre-packaged reagents, i.e. test-packs
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN201280004844.2A 2011-01-08 2012-01-06 用于免疫分析检测的系统 Active CN103430024B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202010094963.8A CN111505265A (zh) 2011-01-08 2012-01-06 用于免疫分析检测的系统
CN201610350276.1A CN106018782A (zh) 2011-01-08 2012-01-06 用于免疫分析检测的系统

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161430963P 2011-01-08 2011-01-08
US61/430,963 2011-01-08
PCT/US2012/020532 WO2012094625A2 (en) 2011-01-08 2012-01-06 Systems for immunoassay tests

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN202010094963.8A Division CN111505265A (zh) 2011-01-08 2012-01-06 用于免疫分析检测的系统
CN201610350276.1A Division CN106018782A (zh) 2011-01-08 2012-01-06 用于免疫分析检测的系统

Publications (2)

Publication Number Publication Date
CN103430024A CN103430024A (zh) 2013-12-04
CN103430024B true CN103430024B (zh) 2016-06-29

Family

ID=46457990

Family Applications (3)

Application Number Title Priority Date Filing Date
CN201280004844.2A Active CN103430024B (zh) 2011-01-08 2012-01-06 用于免疫分析检测的系统
CN201610350276.1A Pending CN106018782A (zh) 2011-01-08 2012-01-06 用于免疫分析检测的系统
CN202010094963.8A Pending CN111505265A (zh) 2011-01-08 2012-01-06 用于免疫分析检测的系统

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201610350276.1A Pending CN106018782A (zh) 2011-01-08 2012-01-06 用于免疫分析检测的系统
CN202010094963.8A Pending CN111505265A (zh) 2011-01-08 2012-01-06 用于免疫分析检测的系统

Country Status (5)

Country Link
US (2) US8753574B2 (https=)
EP (1) EP2661624B1 (https=)
JP (3) JP5922678B2 (https=)
CN (3) CN103430024B (https=)
WO (1) WO2012094625A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD975312S1 (en) 2020-02-14 2023-01-10 Beckman Coulter, Inc. Reagent cartridge

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103430024B (zh) * 2011-01-08 2016-06-29 万迈医疗仪器有限公司 用于免疫分析检测的系统
US9804179B2 (en) 2011-01-08 2017-10-31 Access Medical Systems, Ltd. Systems for immunoassay tests
US9052315B2 (en) 2012-05-09 2015-06-09 Advanced Animal Diagnostics, Inc. Rapid detection of analytes in liquid samples
US10359614B2 (en) 2012-07-03 2019-07-23 Advanced Animal Diagnostics, Inc. Diagnostic apparatus
EP2743694A1 (en) * 2012-12-14 2014-06-18 Numares GmbH Method for supplementing a sample with specific information and sample tube system
FR3000218A1 (fr) * 2012-12-26 2014-06-27 Biomerieux Sa Barrette d'analyse comprenant des moyens pour fixer un cone a ladite barrette
AU2013202778A1 (en) * 2013-03-14 2014-10-02 Gen-Probe Incorporated Systems, methods, and apparatuses for performing automated reagent-based assays
US9797893B2 (en) 2013-05-09 2017-10-24 Advanced Animal Diagnostics, Inc. Rapid detection of analytes in liquid samples
CN105637368B (zh) * 2013-10-07 2017-12-05 万迈医疗仪器有限公司 用于免疫分析试验的盒总成匣
WO2015069911A1 (en) 2013-11-07 2015-05-14 Biotix, Inc. Multiple tube devices and methods of manufacture and use
GB201322081D0 (en) * 2013-12-13 2014-01-29 Ge Healthcare Bio Sciences Ab Circular extractor
KR101588816B1 (ko) * 2014-04-10 2016-01-26 (주)마이크로디지탈 진단용 디텍션 웰 및 이를 갖는 진단용 카트리지
WO2016097711A1 (en) * 2014-12-15 2016-06-23 Randox Laboratories Ltd Improvements relating to biochip storage wells
US9835640B2 (en) 2015-02-13 2017-12-05 Abbott Laboratories Automated storage modules for diagnostic analyzer liquids and related systems and methods
WO2016172800A1 (en) 2015-04-28 2016-11-03 Aterica Inc. Portable organic molecular sensing device and related systems and methods
CN107533052B (zh) * 2015-05-11 2023-04-28 万迈医疗仪器有限公司 在免疫测定中重复使用测试探针和试剂的方法
CN105334318A (zh) * 2015-11-28 2016-02-17 宁波美康生物科技股份有限公司 一种便捷式c反应蛋白检测试剂盒
CN108779458B (zh) * 2015-12-04 2022-07-15 技术合伙公司 试样制备系统和筒座
WO2018071523A1 (en) * 2016-10-11 2018-04-19 Access Medical Systems, Ltd. Optical sensor of bio-molecules using interferometer
US11529628B2 (en) * 2017-04-28 2022-12-20 Ezdia Tech Inc. Automated immunoassay device and method using large magnetic particle complex
EP3655768B1 (en) * 2017-07-21 2026-04-29 Helena Laboratories Corporation Method for depositing antisera in immunofixation electrophoresis
EP3678782B1 (en) 2017-09-06 2025-10-29 Access Medical Systems, Ltd. Ferromagnetic rotors for agitating the liquid in a microwell
EP3986613A1 (en) * 2019-06-21 2022-04-27 Diesse Diagnostica Senese S.p.a. System for single-use immunochemical tests
CN114173667B (zh) * 2019-07-26 2026-01-27 万迈医疗仪器有限公司 用于生化测试的干涉型传感器
WO2021020910A1 (ko) * 2019-07-30 2021-02-04 피씨엘 ㈜ 다중 바이오마커 동시 분석 기기 및 다중 바이오마커 동시 분석 방법
CN110404594B (zh) * 2019-07-31 2024-06-04 深圳麦科田生物医疗技术股份有限公司 样本分析试剂盒
CN110549088B (zh) * 2019-09-01 2024-06-25 浙江联宜电机有限公司 台阶销上料机构
USD925760S1 (en) * 2019-09-17 2021-07-20 Access Medical Systems, Ltd. Interferometric probe for biochemical testing
CN112539720A (zh) * 2020-12-23 2021-03-23 北京宝隆特设备检测有限公司 一种高效的超声波测厚仪及其使用方法
WO2023090446A1 (ja) * 2021-11-22 2023-05-25 国立大学法人東京大学 検体分析装置、検体分析方法
WO2024259688A1 (zh) * 2023-06-21 2024-12-26 深圳迈瑞生物医疗电子股份有限公司 样本分析仪、试剂盒、样本分析仪的控制方法
CN117533661B (zh) * 2023-12-28 2025-11-11 长沙迈迪克智能科技有限公司 用于血液储存管理系统的血框取送装置及血液储存管理系统

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1437707A (zh) * 2000-04-28 2003-08-20 三菱化学株式会社 自动检测检测盒及利用它进行检测的方法
CN1526074A (zh) * 2001-05-09 2004-09-01 ������˹-ϣ���¹�˾ 检测系统
WO2010101931A2 (en) * 2009-03-03 2010-09-10 Access Medical System Co., Ltd. Detection system and method for high sensitivity fluorescent assays

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1499989A (en) * 1923-04-20 1924-07-01 Lehmann Franz Vise for use with machine tools
US2754708A (en) * 1953-08-25 1956-07-17 Multiple Die Vise Co Inc Vise for irregularly shaped objects
US2882771A (en) * 1956-06-22 1959-04-21 Ronald R Blazek Work-holding device having plungers actuated by hydraulic fluid composed of a fusible alloy
US4447546A (en) 1982-08-23 1984-05-08 Myron J. Block Fluorescent immunoassay employing optical fiber in capillary tube
JPS59175976A (ja) * 1983-03-23 1984-10-05 三菱電機株式会社 ロボツトのハンド装置
US4752564A (en) * 1983-07-12 1988-06-21 Phillips Petroleum Company Fermentation method and apparatus
US4572564A (en) * 1984-07-12 1986-02-25 General Electric Company Adaptive gripping device
US4631815A (en) * 1985-12-18 1986-12-30 Amp Incorporated Pick-up head
US5268486A (en) 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US5011207A (en) * 1987-08-03 1991-04-30 Stevens S Scott Robotic end effector for grasping objects
US4891321A (en) * 1987-10-21 1990-01-02 Hubscher Thomas T Apparatus for performing determinations of immune reactants in biological fluids
JPH03117587U (https=) * 1990-03-14 1991-12-04
CA2384519C (en) * 1991-03-04 2006-08-15 Bayer Corporation Automated analyzer
US6498037B1 (en) * 1991-03-04 2002-12-24 Bayer Corporation Method of handling reagents in a random access protocol
FI930440A0 (fi) * 1993-02-01 1993-02-01 Labsystems Oy Bestaemningsfoerfarande
US5650334A (en) 1995-08-31 1997-07-22 First Medical, Inc. Fluorescent labelling compositions and methods for their use
US5884906A (en) * 1995-10-16 1999-03-23 Morse; Loren Hydraulically compensating jaw for holding multiple work pieces
US6345816B1 (en) * 2000-05-11 2002-02-12 Snap Jaws Manufacturing Co. Hydraulic vise jaws
US6464939B1 (en) * 2000-07-06 2002-10-15 Varian, Inc. Saliva testing and confirmation device
CN2473613Y (zh) * 2001-04-26 2002-01-23 雷刚平 粪便采集盛放器
JP2004205268A (ja) * 2002-12-24 2004-07-22 Canon Inc 蛍光免疫測定方法及び蛍光免疫測定装置
CN102072961A (zh) * 2003-07-17 2011-05-25 三菱化学美迪恩斯株式会社 用于自动测定的检测盒和使用该检测盒的测定装置
TWM246495U (en) * 2003-10-31 2004-10-11 Hon Hai Prec Ind Co Ltd Automatic apparatus for assembling bearig to motor
GB0503836D0 (en) * 2005-02-24 2005-04-06 Axis Shield Asa Method
US8075850B2 (en) * 2006-01-13 2011-12-13 The Bode Technology Group, Inc. Touch evidence collection apparatus and method
CN102224410B (zh) * 2008-09-24 2017-02-08 施特劳斯控股公司 用于测试分析物的成像分析仪
CN103430024B (zh) * 2011-01-08 2016-06-29 万迈医疗仪器有限公司 用于免疫分析检测的系统
CN105181659A (zh) 2011-04-20 2015-12-23 万迈医疗仪器有限公司 发光聚合物循环扩增
CN102358988B (zh) * 2011-11-14 2013-06-12 宁波慈星股份有限公司 沉降三角控制装置
US9568431B2 (en) * 2012-04-16 2017-02-14 Access Medical Systems, Ltd. Luminescent immunoassays for quantitating analytes having a wide concentration range
US8534728B1 (en) * 2012-11-19 2013-09-17 Harris Corporation Adaptive robotic gripper
CN103753242A (zh) * 2013-11-25 2014-04-30 重庆舰帏机械有限公司 曲轴夹具

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1437707A (zh) * 2000-04-28 2003-08-20 三菱化学株式会社 自动检测检测盒及利用它进行检测的方法
CN1526074A (zh) * 2001-05-09 2004-09-01 ������˹-ϣ���¹�˾ 检测系统
WO2010101931A2 (en) * 2009-03-03 2010-09-10 Access Medical System Co., Ltd. Detection system and method for high sensitivity fluorescent assays

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD975312S1 (en) 2020-02-14 2023-01-10 Beckman Coulter, Inc. Reagent cartridge
USD1012310S1 (en) 2020-02-14 2024-01-23 Beckman Coulter, Inc. Reagent cartridge

Also Published As

Publication number Publication date
WO2012094625A3 (en) 2013-01-17
CN111505265A (zh) 2020-08-07
EP2661624A2 (en) 2013-11-13
CN103430024A (zh) 2013-12-04
JP2016166882A (ja) 2016-09-15
WO2012094625A2 (en) 2012-07-12
US20130295591A1 (en) 2013-11-07
JP5922678B2 (ja) 2016-05-24
US9468926B2 (en) 2016-10-18
JP2018054637A (ja) 2018-04-05
EP2661624B1 (en) 2017-08-02
US8753574B2 (en) 2014-06-17
JP2014501933A (ja) 2014-01-23
JP6279649B2 (ja) 2018-02-14
EP2661624A4 (en) 2014-05-28
CN106018782A (zh) 2016-10-12
US20140295578A1 (en) 2014-10-02

Similar Documents

Publication Publication Date Title
CN103430024B (zh) 用于免疫分析检测的系统
US11879901B2 (en) Cartridges for immunoassay tests and methods of using the same
US12153061B2 (en) Cartridge assembly tray for immunoassay tests
US4874691A (en) Membrane-supported immunoassays
US20160209409A1 (en) Device and Method for Detecting Analyte by Movement of Particles
KR20070116615A (ko) 내부 검량 시스템을 사용하는 진단 시험용 키트
CA2745442C (en) Test element having combined control and calibration zone
KR101916608B1 (ko) 생화학-면역 하이브리드 바이오센서 및 이를 포함하는 센서시스템
US8501496B2 (en) Immunoassay cuvettes
HK1163817B (en) Test element having combined control and calibration zone

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant