JP5922678B2 - 免疫学的検定試験のためのシステム - Google Patents

免疫学的検定試験のためのシステム Download PDF

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JP5922678B2
JP5922678B2 JP2013548586A JP2013548586A JP5922678B2 JP 5922678 B2 JP5922678 B2 JP 5922678B2 JP 2013548586 A JP2013548586 A JP 2013548586A JP 2013548586 A JP2013548586 A JP 2013548586A JP 5922678 B2 JP5922678 B2 JP 5922678B2
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probe
well
cartridge
reagent
rod
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JP2014501933A (ja
JP2014501933A5 (https=
Inventor
タン ホン
タン ホン
ミン シャ
ミン シャ
ユシャン タン
ユシャン タン
チュン チェン
チュン チェン
エルファ カオ
エルファ カオ
ケンチャン リ
ケンチャン リ
エフ.ズック ロバート
エフ.ズック ロバート
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アクセス メディカル システムズ,リミティド
アクセス メディカル システムズ,リミティド
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent
    • B01L3/527Containers specially adapted for storing or dispensing a reagent for a plurality of reagents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/042Caps; Plugs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/045Connecting closures to device or container whereby the whole cover is slidable
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0429Sample carriers adapted for special purposes
    • G01N2035/0436Sample carriers adapted for special purposes with pre-packaged reagents, i.e. test-packs
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2013548586A 2011-01-08 2012-01-06 免疫学的検定試験のためのシステム Active JP5922678B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161430963P 2011-01-08 2011-01-08
US61/430,963 2011-01-08
PCT/US2012/020532 WO2012094625A2 (en) 2011-01-08 2012-01-06 Systems for immunoassay tests

Related Child Applications (1)

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JP2016081275A Division JP6279649B2 (ja) 2011-01-08 2016-04-14 免疫学的検定試験のためのシステム

Publications (3)

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JP2014501933A JP2014501933A (ja) 2014-01-23
JP2014501933A5 JP2014501933A5 (https=) 2015-02-26
JP5922678B2 true JP5922678B2 (ja) 2016-05-24

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JP2013548586A Active JP5922678B2 (ja) 2011-01-08 2012-01-06 免疫学的検定試験のためのシステム
JP2016081275A Active JP6279649B2 (ja) 2011-01-08 2016-04-14 免疫学的検定試験のためのシステム
JP2018004219A Pending JP2018054637A (ja) 2011-01-08 2018-01-15 免疫学的検定試験のためのシステム

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JP2018004219A Pending JP2018054637A (ja) 2011-01-08 2018-01-15 免疫学的検定試験のためのシステム

Country Status (5)

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US (2) US8753574B2 (https=)
EP (1) EP2661624B1 (https=)
JP (3) JP5922678B2 (https=)
CN (3) CN106018782A (https=)
WO (1) WO2012094625A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018054637A (ja) * 2011-01-08 2018-04-05 アクセス メディカル システムズ,リミティド 免疫学的検定試験のためのシステム

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9804179B2 (en) 2011-01-08 2017-10-31 Access Medical Systems, Ltd. Systems for immunoassay tests
US9052315B2 (en) 2012-05-09 2015-06-09 Advanced Animal Diagnostics, Inc. Rapid detection of analytes in liquid samples
US10359614B2 (en) 2012-07-03 2019-07-23 Advanced Animal Diagnostics, Inc. Diagnostic apparatus
EP2743694A1 (en) 2012-12-14 2014-06-18 Numares GmbH Method for supplementing a sample with specific information and sample tube system
FR3000218A1 (fr) 2012-12-26 2014-06-27 Biomerieux Sa Barrette d'analyse comprenant des moyens pour fixer un cone a ladite barrette
AU2013202778A1 (en) * 2013-03-14 2014-10-02 Gen-Probe Incorporated Systems, methods, and apparatuses for performing automated reagent-based assays
US9797893B2 (en) 2013-05-09 2017-10-24 Advanced Animal Diagnostics, Inc. Rapid detection of analytes in liquid samples
CN105637368B (zh) 2013-10-07 2017-12-05 万迈医疗仪器有限公司 用于免疫分析试验的盒总成匣
US10639626B2 (en) 2013-11-07 2020-05-05 Biotix, Inc. Multiple tube devices and methods of manufacture and use
GB201322081D0 (en) * 2013-12-13 2014-01-29 Ge Healthcare Bio Sciences Ab Circular extractor
KR101588816B1 (ko) * 2014-04-10 2016-01-26 (주)마이크로디지탈 진단용 디텍션 웰 및 이를 갖는 진단용 카트리지
US10646876B2 (en) 2014-12-15 2020-05-12 Randox Laboratories Ltd. Biochip storage wells
WO2016130964A1 (en) 2015-02-13 2016-08-18 Abbott Laboratories Decapping and capping apparatus, systems and methods for use in diagnostic analyzers
CA2983806C (en) * 2015-04-28 2023-06-13 Aterica Inc. Portable organic molecular sensing device and related systems and methods
WO2016183092A1 (en) * 2015-05-11 2016-11-17 Access Medical Systems, Ltd. Method for re-using test probe and reagents in an immunoassay
CN105334318A (zh) * 2015-11-28 2016-02-17 宁波美康生物科技股份有限公司 一种便捷式c反应蛋白检测试剂盒
US10857538B2 (en) 2015-12-04 2020-12-08 Ttp Plc Sample preparation system and cartridge
WO2018071523A1 (en) * 2016-10-11 2018-04-19 Access Medical Systems, Ltd. Optical sensor of bio-molecules using interferometer
WO2018199689A2 (ko) * 2017-04-28 2018-11-01 주식회사 이지다이아텍 거대 자성입자 복합체를 이용한 자동 면역분석장치 및 방법
CN111051873A (zh) * 2017-07-21 2020-04-21 海伦娜实验室公司 在免疫固定电泳中沉积抗血清的系统和方法
CN111050914B (zh) 2017-09-06 2023-04-04 万迈医疗仪器有限公司 用于搅动微孔中的液体的铁磁转子
WO2020254472A1 (en) * 2019-06-21 2020-12-24 Diesse Diagnostica Senese S.P.A. System for single-use immunochemical tests
EP4003175A4 (en) * 2019-07-26 2023-08-30 Access Medical Systems, Ltd. Interferometric sensors for biochemical testing
KR102204918B1 (ko) * 2019-07-30 2021-01-19 피씨엘 주식회사 다중 바이오마커 동시 분석 기기 및 다중 바이오마커 동시 분석 방법
CN110404594B (zh) * 2019-07-31 2024-06-04 深圳麦科田生物医疗技术股份有限公司 样本分析试剂盒
CN110549088B (zh) * 2019-09-01 2024-06-25 浙江联宜电机有限公司 台阶销上料机构
USD925760S1 (en) * 2019-09-17 2021-07-20 Access Medical Systems, Ltd. Interferometric probe for biochemical testing
USD975312S1 (en) 2020-02-14 2023-01-10 Beckman Coulter, Inc. Reagent cartridge
CN112539720A (zh) * 2020-12-23 2021-03-23 北京宝隆特设备检测有限公司 一种高效的超声波测厚仪及其使用方法
JPWO2023090446A1 (https=) * 2021-11-22 2023-05-25
CN121420197A (zh) * 2023-06-21 2026-01-27 深圳迈瑞生物医疗电子股份有限公司 样本分析仪、试剂盒、样本分析仪的控制方法
CN117533661B (zh) * 2023-12-28 2025-11-11 长沙迈迪克智能科技有限公司 用于血液储存管理系统的血框取送装置及血液储存管理系统

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1499989A (en) * 1923-04-20 1924-07-01 Lehmann Franz Vise for use with machine tools
US2754708A (en) * 1953-08-25 1956-07-17 Multiple Die Vise Co Inc Vise for irregularly shaped objects
US2882771A (en) * 1956-06-22 1959-04-21 Ronald R Blazek Work-holding device having plungers actuated by hydraulic fluid composed of a fusible alloy
US4447546A (en) 1982-08-23 1984-05-08 Myron J. Block Fluorescent immunoassay employing optical fiber in capillary tube
JPS59175976A (ja) * 1983-03-23 1984-10-05 三菱電機株式会社 ロボツトのハンド装置
US4752564A (en) * 1983-07-12 1988-06-21 Phillips Petroleum Company Fermentation method and apparatus
US4572564A (en) * 1984-07-12 1986-02-25 General Electric Company Adaptive gripping device
US4631815A (en) * 1985-12-18 1986-12-30 Amp Incorporated Pick-up head
US5268486A (en) 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US5011207A (en) * 1987-08-03 1991-04-30 Stevens S Scott Robotic end effector for grasping objects
US4891321A (en) * 1987-10-21 1990-01-02 Hubscher Thomas T Apparatus for performing determinations of immune reactants in biological fluids
JPH03117587U (https=) * 1990-03-14 1991-12-04
CA2384535C (en) * 1991-03-04 2006-08-15 Bayer Corporation Automated analyzer
US6498037B1 (en) * 1991-03-04 2002-12-24 Bayer Corporation Method of handling reagents in a random access protocol
FI930440A0 (fi) * 1993-02-01 1993-02-01 Labsystems Oy Bestaemningsfoerfarande
US5650334A (en) 1995-08-31 1997-07-22 First Medical, Inc. Fluorescent labelling compositions and methods for their use
US5884906A (en) * 1995-10-16 1999-03-23 Morse; Loren Hydraulically compensating jaw for holding multiple work pieces
CN1256588C (zh) * 2000-04-28 2006-05-17 株式会社三菱化学药得论 自动检测检测盒及利用它进行检测的方法
US6345816B1 (en) * 2000-05-11 2002-02-12 Snap Jaws Manufacturing Co. Hydraulic vise jaws
US6464939B1 (en) * 2000-07-06 2002-10-15 Varian, Inc. Saliva testing and confirmation device
CN2473613Y (zh) * 2001-04-26 2002-01-23 雷刚平 粪便采集盛放器
SK286037B6 (sk) 2001-05-09 2008-01-07 Axis-Shield Asa Testovací prístroj, testovacia náplň, testovacie zariadenie, jeho použitie a spôsob testovania
JP2004205268A (ja) * 2002-12-24 2004-07-22 Canon Inc 蛍光免疫測定方法及び蛍光免疫測定装置
EP1650570B1 (en) * 2003-07-17 2021-05-26 LSI Medience Corporation Apparatus for use in measuring a component contained in a sample comprising a measuring device and a cartridge
TWM246495U (en) * 2003-10-31 2004-10-11 Hon Hai Prec Ind Co Ltd Automatic apparatus for assembling bearig to motor
GB0503836D0 (en) * 2005-02-24 2005-04-06 Axis Shield Asa Method
US8075850B2 (en) * 2006-01-13 2011-12-13 The Bode Technology Group, Inc. Touch evidence collection apparatus and method
CN102224260B (zh) * 2008-09-24 2015-11-25 施特劳斯控股公司 用于检测分析物的试剂盒和装置
EP2404162B1 (en) 2009-03-03 2017-12-27 Access Medical System Co., Ltd. Detection system and method for high sensitivity fluorescent assays
CN106018782A (zh) * 2011-01-08 2016-10-12 万迈医疗仪器有限公司 用于免疫分析检测的系统
CN103608675B (zh) 2011-04-20 2015-07-22 万迈医疗仪器有限公司 发光聚合物循环扩增
CN102358988B (zh) * 2011-11-14 2013-06-12 宁波慈星股份有限公司 沉降三角控制装置
US9568431B2 (en) * 2012-04-16 2017-02-14 Access Medical Systems, Ltd. Luminescent immunoassays for quantitating analytes having a wide concentration range
US8534728B1 (en) * 2012-11-19 2013-09-17 Harris Corporation Adaptive robotic gripper
CN103753242A (zh) * 2013-11-25 2014-04-30 重庆舰帏机械有限公司 曲轴夹具

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018054637A (ja) * 2011-01-08 2018-04-05 アクセス メディカル システムズ,リミティド 免疫学的検定試験のためのシステム

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Publication number Publication date
CN106018782A (zh) 2016-10-12
EP2661624A4 (en) 2014-05-28
JP2016166882A (ja) 2016-09-15
JP6279649B2 (ja) 2018-02-14
CN111505265A (zh) 2020-08-07
JP2014501933A (ja) 2014-01-23
US9468926B2 (en) 2016-10-18
JP2018054637A (ja) 2018-04-05
WO2012094625A3 (en) 2013-01-17
EP2661624A2 (en) 2013-11-13
CN103430024B (zh) 2016-06-29
US20140295578A1 (en) 2014-10-02
US20130295591A1 (en) 2013-11-07
CN103430024A (zh) 2013-12-04
US8753574B2 (en) 2014-06-17
EP2661624B1 (en) 2017-08-02
WO2012094625A2 (en) 2012-07-12

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