CN103417599A - Soft plaster substrate prepared from traditional Chinese medicine ingredients and preparation method thereof - Google Patents

Soft plaster substrate prepared from traditional Chinese medicine ingredients and preparation method thereof Download PDF

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Publication number
CN103417599A
CN103417599A CN2013103764991A CN201310376499A CN103417599A CN 103417599 A CN103417599 A CN 103417599A CN 2013103764991 A CN2013103764991 A CN 2013103764991A CN 201310376499 A CN201310376499 A CN 201310376499A CN 103417599 A CN103417599 A CN 103417599A
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China
Prior art keywords
plaster substrate
soft
chinese medicine
traditional chinese
preparation
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CN2013103764991A
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Chinese (zh)
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CN103417599B (en
Inventor
韦英才
杨明德
黄锦威
莫祖财
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GUILIN ANHE PHARMACEUTICAL Co Ltd
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GUILIN ANHE PHARMACEUTICAL Co Ltd
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Priority to CN201310376499.1A priority Critical patent/CN103417599B/en
Publication of CN103417599A publication Critical patent/CN103417599A/en
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Publication of CN103417599B publication Critical patent/CN103417599B/en
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a soft plaster substrate prepared from traditional Chinese medicine ingredients. The soft plaster substrate is prepared from gnetum parvifolium, garden balsam stems, olibanum and myrrh. The raw material mass ratio of the gnetum parvifolium, the garden balsam stems, the olibanum and the myrrh is 3-5:3-5:2-3:2-3. The invention further relates to a preparation method of the soft plaster substrate prepared from pure traditional Chinese medicine ingredients. The pure traditional Chinese medicine soft plaster substrate prepared with the method has the functions of menstruation improvement and pain relief, can be pasted adhesively and is easy to paste and tear off. The adhesive plaster substrate will not cause allergy and overcomes the defects that plasters in the current market adopt zinc oxide, rubber and other anaphylactic auxiliary materials. The plaster substrate is directly made into adhesive soft material by the utilization of the characteristics of the medicinal materials, and thus the medicine effect is more obvious. The soft plaster substrate prepared from traditional Chinese medicine ingredients can be organically combined with various medicines to be made into various externally-applied medicine plasters, and the soft plaster substrate prepared from traditional Chinese medicine ingredients can be used for treating injuries, rheumatism, pains and the like, relieving rheumatic pains, dredging meridians, dispelling colds and rheumatism, warming tendons, removing stasis, eliminating swelling, diminishing inflammation and the like.

Description

Soft substrate of plaster that Chinese medicinal ingredients is made and preparation method thereof
Technical field
The present invention relates to plaster, soft substrate of plaster that especially Chinese medicinal ingredients is made and preparation method thereof.
Background technology
On market, all emplastrumes are to use the soft material of the anaphylaxis adjuvants such as zinc oxide and rubber as the plaster stroma soft material now, have the skin hypersensitivity reaction, also affect the curative effect of medicine.
The cataplasma plaster is to take high molecular weight water soluble polymer as the matrix scaffold material, be equipped with the external use plaster of part natural plant, rubber plaster be take the external use plaster that natural rubber and pure matter zinc oxide are raw material, the external use plaster that pressure sensitive adhesive is is raw material by acrylic compounds, rubber-like.Black plaster is exactly traditional lead plaster.
The rubber paste in traditional black plaster, modern times, although determined curative effect, black plaster is used inconvenience, pollution clothes, processing technology affects environment.The zest of rubber paste, anaphylaxis, easy aging etc. have limited its clinical use.The research and development of Chinese medicine patcher and Industry Promotion, enriched the type of dosage form of external Chinese medicament, although it has series of advantages, characteristics, but and do not mean that external use plasters such as can replacing rubber paste fully, they differ from one another, conduct is arranged in people prevent and cure diseases, and Chinese medicine patcher just provides new medication to select for vast, convenient treatment.
Summary of the invention
The purpose of this invention is to provide the soft substrate of plaster that a kind of pure Chinese medicinal ingredients is made.
The soft substrate of the plaster that Chinese medicinal ingredients of the present invention is made, by boon wind, Herba speranskiae tuberculatae, the composition in Olibanum and Myrrha is made.
The above-mentioned raw materials weight proportion is: boon wind: Herba speranskiae tuberculatae: Olibanum: Myrrha=3 ~ 5:3 ~ 5:2 ~ 3:2 ~ 3.
Raw material weight proportioning is: boon wind: Herba speranskiae tuberculatae: Olibanum: Myrrha=3:3:2:2.
Another object of the present invention is to provide the preparation method of the soft substrate of plaster that pure Chinese medicinal ingredients makes.
This preparation method, comprise the steps:
A. boon wind and Herba speranskiae tuberculatae mixing are beaten to powder,
B.The alcohol-water mixed solvent extracts the composition in Olibanum and Myrrha, then
C. extract is concentrated,
D. A gains and C gains are mixed and made into to soft material.
Wherein in steps A, beating powder fineness is 100 ~ 200 orders.
Wherein in step B, the weight ratio of mixed solvent is ethanol/water=3 ~ 6/7 ~ 4, the consumption of mixed solvent is raw material weight 3 ~ 6 times, extracting temperature is 40 ~ 60 ℃, extraction time is 8 ~ 12 hours, extracting mode adopts reflux, extract.
Wherein at step C, being concentrated to Baume degrees is 22 ~ 27 °.
Wherein, at step D, the C gains are joined in the A gains, stir evenly.
The soft substrate of the plaster that Chinese medicinal ingredients of the present invention is made has colloidality, sticks on human body skin and easily glue and easily take off, within 24 hours, do not fall, do not itch, do not have anaphylactoid phenomenon to occur, solved and made with zinc oxide and rubber etc. the disadvantage that the substrate material easily produces the anaphylaxis adjuvant on the market, simultaneously blood circulation promoting and blood stasis dispelling, stimulate the menstrual flow, pain relieving, can strengthen the drug effect efficacy of a drug stronger than single drug application penetration, the patient is reflected well, also environmental protection, have novelty.
In a word, its innovative point is:
1) the full Chinese medicine of making have stimulate the menstrual flow, pain relieving also has colloidality and pastes and easily stickyly easily to remove, do not produce irritated sticky cream base matter and solve on existing market the disadvantage of the anaphylaxis adjuvants such as zinc oxide and rubber for all emplastrumes;
2) utilize character and the characteristics of medical material itself, directly make bonding soft material, make drug effect more obvious.
The soft substrate of the plaster that Chinese medicinal ingredients of the present invention is made, can with various medicine organic composites, make various external used medicine plaster, be used for the treatment of the plaster of wound, wet, pain etc. and dispelling wind and removing obstruction in the collateral, dispelling cold and removing dampness, warm muscle eliminating stagnation, detumescence, antiinflammatory etc.
The accompanying drawing explanation
Fig. 1 is the soft matrix composition flow chart of plaster that Chinese medicinal ingredients is made.
The specific embodiment
Boon wind: Herba speranskiae tuberculatae: Olibanum: Myrrha=3:3:2:2.
A. boon wind and Herba speranskiae tuberculatae mixing are beaten to powder, becoming fineness is 100 orders.
B.The alcohol-water mixed solvent extracts the composition in Olibanum and Myrrha, wherein in step B, the weight ratio of mixed solvent is ethanol/water=5/5, the consumption of mixed solvent is raw material weight 5 times, extracting temperature is 50 ℃, extraction time is 10 hours, and extracting mode adopts reflux, extract.
Then
C. to be concentrated to Baume degrees be 25 ° to extract.
D. the C gains are joined in the A gains, stir evenly.Be mixed and made into soft material.

Claims (8)

1. the soft substrate of plaster that Chinese medicinal ingredients is made is characterized in that: by boon wind, Herba speranskiae tuberculatae, the composition in Olibanum and Myrrha is made.
2. according to the soft substrate of claim 1, it is characterized in that: the raw material weight proportioning is: boon wind: Herba speranskiae tuberculatae: Olibanum: Myrrha=3 ~ 5:3 ~ 5:2 ~ 3:2 ~ 3.
3. according to the soft substrate of claim 1, it is characterized in that: the raw material weight proportioning is: boon wind: Herba speranskiae tuberculatae: Olibanum: Myrrha=3:3:2:2.
4. the preparation method of the soft substrate of claim 1, is characterized in that: comprise the steps:
A. boon wind and Herba speranskiae tuberculatae mixing are beaten to powder,
The alcohol-water mixed solvent extracts the composition in Olibanum and Myrrha, then
C. extract is concentrated,
D. A gains and C gains are mixed and made into to soft material.
5. according to the preparation method of claim 4, it is characterized in that: beating powder fineness in steps A is 100 ~ 200 orders.
6. according to the preparation method of claim 4, it is characterized in that: in step B, the weight ratio of mixed solvent is ethanol/water=3 ~ 6/7 ~ 4, the consumption of mixed solvent is raw material weight 3 ~ 6 times, extracting temperature is 40 ~ 60 ℃, extraction time is 8 ~ 12 hours, and extracting mode adopts reflux, extract.
7. according to the preparation method of claim 4, it is characterized in that: being concentrated to Baume degrees at step C is 22 ~ 27 °.
8. according to the preparation method of claim 4, it is characterized in that: at step D, the C gains are joined in the A gains, stir evenly.
CN201310376499.1A 2013-08-27 2013-08-27 Soft plaster substrate prepared from traditional Chinese medicine ingredients and preparation method thereof Expired - Fee Related CN103417599B (en)

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CN201310376499.1A CN103417599B (en) 2013-08-27 2013-08-27 Soft plaster substrate prepared from traditional Chinese medicine ingredients and preparation method thereof

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CN103417599B CN103417599B (en) 2015-04-22

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103720677A (en) * 2014-01-15 2014-04-16 桂林安和药业有限公司 Plaster capable of repeatedly peeling and repeatedly coating with medicines
CN105816510A (en) * 2016-04-07 2016-08-03 桂林安和药业有限公司 Muscle pain patch for soft matrix

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1698682A (en) * 2004-05-19 2005-11-23 广西玉林制药有限责任公司 Chinese traditional medicine composition with effects of activating blood circulation, dissipating blood stasis, relaxing, activating the tendons, reducing swelling and easing pain and preparation met
CN1813976A (en) * 2005-11-28 2006-08-09 蓝子花 Panicled swallowwort root collateral-flow-activating ointment for treating pain from affection by dampness
CN101637598A (en) * 2008-07-28 2010-02-03 北京中泰天和科技有限公司 Externally applied medicine for treating lumbar muscle degeneration and preparation method
CN102362997A (en) * 2011-10-31 2012-02-29 贾瑞飞 Medicine used for treating knee osteoarthritis, and preparation method thereof
CN102580009A (en) * 2012-03-15 2012-07-18 徐利华 Plaster for treating rheumatism bone aching in neck, shoulders, waist and legs

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1698682A (en) * 2004-05-19 2005-11-23 广西玉林制药有限责任公司 Chinese traditional medicine composition with effects of activating blood circulation, dissipating blood stasis, relaxing, activating the tendons, reducing swelling and easing pain and preparation met
CN1813976A (en) * 2005-11-28 2006-08-09 蓝子花 Panicled swallowwort root collateral-flow-activating ointment for treating pain from affection by dampness
CN101637598A (en) * 2008-07-28 2010-02-03 北京中泰天和科技有限公司 Externally applied medicine for treating lumbar muscle degeneration and preparation method
CN102362997A (en) * 2011-10-31 2012-02-29 贾瑞飞 Medicine used for treating knee osteoarthritis, and preparation method thereof
CN102580009A (en) * 2012-03-15 2012-07-18 徐利华 Plaster for treating rheumatism bone aching in neck, shoulders, waist and legs

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103720677A (en) * 2014-01-15 2014-04-16 桂林安和药业有限公司 Plaster capable of repeatedly peeling and repeatedly coating with medicines
CN105816510A (en) * 2016-04-07 2016-08-03 桂林安和药业有限公司 Muscle pain patch for soft matrix

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