CN102362997A - Medicine used for treating knee osteoarthritis, and preparation method thereof - Google Patents

Medicine used for treating knee osteoarthritis, and preparation method thereof Download PDF

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CN102362997A
CN102362997A CN2011103371298A CN201110337129A CN102362997A CN 102362997 A CN102362997 A CN 102362997A CN 2011103371298 A CN2011103371298 A CN 2011103371298A CN 201110337129 A CN201110337129 A CN 201110337129A CN 102362997 A CN102362997 A CN 102362997A
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medicine
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knee joint
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贾瑞飞
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Abstract

The invention relates to a medicine used for treating knee osteoarthritis, and a preparation method thereof. The medicine used for treating knee osteoarthritis is prepared from raw materials of: 25 to 35g of variegated coralbean bark, 25 to 35g of speranskia tuberculata, 25 to 35g of Japanese clubmoss herb, 20 to 30g of slenderstyle acanthopanax root-bark, 20 to 30g of Chinese clematis root and rhizome, 20 to 30g of doubleteeth angelica root, 18 to 25g of raw common monkshood mother-root, 18 to 25g of raw kusnezoff monkshood mother-root, 15 to 20g of common burreed tuber, 10 to 15 parts of frankincense, 10 to 15g of myrrh, 20 to 25g of ligusticum, 25 to 25g of argy wormwood leaf, and 100 to 150ml of rice vinegar. According to the invention, a conservative therapy with an internal-disease external-treatment theory in Chinese medical science is adopted, and the pure traditional Chinese medicine preparation is adopted, such that surgery pains and costs of western medicine are reduced. The medicine provided by the invention is not absorbed by stomach, intestines, liver or kidney, such that no toxic or side-effect is brought to human bodies, and the occurrence of sequel is avoided. With the medicine, knee osteoarthritis is not easy to reoccur.

Description

A kind of medicine of treating knee joint osteoarthritis and preparation method thereof
Technical field
The present invention relates to a kind of medicine of treating knee joint osteoarthritis and preparation method thereof.
Background technology
Knee joint osteoarthritis is the commonly encountered diseases and the frequently-occurring disease of middle-aged and elderly people, has a strong impact on the daily life and the work of middle-aged and elderly people, has very high sickness rate and disability rate.Constitutional or Secondary cases degenerative change appear in the their early stage articular cartilage, and destroy and hyperosteogeny with subchondral bone, thereby make the joint be destroyed and produce deformity gradually.The whole process of its pathological changes not only has influence on knee cartilage, also relates to muscle around meniscus, subchondral bone, ligament, joint capsule, synovial membrane and the joint.
The main cause that causes knee joint osteoarthritis is kneed damage, chronic strain, and hypoimmunity, cold stimulation, metabolism disorders etc. are the common causes that causes knee joint osteoarthritis.The traditional Chinese medical science is called " rheumatism involving the bone ", " arthralgia aggravated by cold ", with old, and long-term strain, caused by liver and kidney deficiency, muscles and bones mistake is supported, and insufficiency of vital energy and blood is experienced wind, cold, damp etc. and is fallen ill, and kidney governing bones, liver governing tendons, muscle attach bone.Therefore " the Zhang Shi doctor is logical " proposes " knee joint is a house of tendons ... gonalgia does not have to be had not because of the liver person who suffer from deficiency of kidney Yang ".Be clinical common chronic degenerative diseases, be more common in middle-aged and elderly people, the pain when its early symptom is stair activity is one-sided or bilateral alternately occurs, arthroncus, or hydrarthrosis, and the genu varum deformity appears in severe patient.The Therapeutic Method of knee joint osteoarthritis is a lot, and physiotherapy, pharmacotherapy, operative therapy, Chinese traditional treatment etc. are arranged, and naturopathy can only can't be cured disease by alleviating pain for the patient, only be fit to do auxiliary treatment.Common drug treatment stimulating intestine and stomach, very big to actual bodily harm, the patient of knee joint osteoarthritis is middle-aged and elderly people mostly, does not advise using general Drug therapy.Expenses of surgical treatment is high, and post-operative recovery is slow and the treatment risk is bigger, does not advise using.
Summary of the invention
The present invention is exactly to the problems referred to above, and a kind of treatment scheme of tcm methods treatment knee joint osteoarthritis is provided.The present invention can well be alleviated and treatment of arthritis, and can obtain the form of Chinese drug that the patient takes like a shot.
Technical scheme provided by the invention is:
A kind of medicine of treating knee joint osteoarthritis, by following preparation of raw material,
Cortex erythrinae 25-35g, Herba speranskiae tuberculatae 25-35g, Herba Lycopodii 25-35g, Cortex Acanthopancis 20-30g, Radix Clematidis 20-30g, Radix Angelicae Pubescentis 20-30g, Radix Aconiti 18-25g, Radix Aconiti Kusnezoffii 18-25g, triangular 15-20g, Olibanum 10-15g, Myrrha 10-15g, Radix Angelicae Sinensis 20-25g, Folium Artemisiae Argyi 25-35g, rice vinegar 100-150ml.
Concrete, said a kind of medicine of treating knee joint osteoarthritis, by following preparation of raw material,
Cortex erythrinae 28-32g, Herba speranskiae tuberculatae 28-32g, Herba Lycopodii 28-32g, Cortex Acanthopancis 24-26g, Radix Clematidis 24-26g, Radix Angelicae Pubescentis 24-26g, Radix Aconiti 21-23g, Radix Aconiti Kusnezoffii 21-23g, triangular 16-18g, Olibanum 12-13g, Myrrha 12-13g, Radix Angelicae Sinensis 22-23g, Folium Artemisiae Argyi 27-32g, rice vinegar 120-130ml.
Concrete, said a kind of medicine of treating knee joint osteoarthritis, by following preparation of raw material,
Cortex erythrinae 30g, Herba speranskiae tuberculatae 30g, Herba Lycopodii 30g, Cortex Acanthopancis 25g, Radix Clematidis 25g, Radix Angelicae Pubescentis 25g, Radix Aconiti 22g, Radix Aconiti Kusnezoffii 22g, triangular 17g, Olibanum 12g, Myrrha 12g, Radix Angelicae Sinensis 22-23g, Folium Artemisiae Argyi 30g, rice vinegar 120-130ml.
A kind of method for preparing of treating the knee joint osteoarthritis medicine,
1) according to the proportion relation preparation raw material: Cortex erythrinae, Herba speranskiae tuberculatae, Herba Lycopodii, Cortex Acanthopancis, Radix Clematidis, Radix Angelicae Pubescentis, Radix Aconiti, Radix Aconiti Kusnezoffii, triangular, Olibanum, Myrrha, Radix Angelicae Sinensis, Folium Artemisiae Argyi;
2), become 60 purpose powder with the raw material pulverizing for preparing;
3) powder and rice vinegar are mixed into thick paste, can use.
Prepare 1 of 20ml disposable syringe, 95% medical alcohol 100ml, two of textile thick towels, 1 of hot water basin.
Method for using: with the thick paste medicine, stick in the kneecap joint or obvious sore place, medicine thickness is 1cm.Half basin hot water is put into towel, and taking-up is wrung out, and applies to cover on medicine.Press shallow ridges circlewise along 1cm place, medicine edge.Extract ethanol 20ml with syringe, drip along annular groove and inner surface and spread, light ethanol.Treat medicine heating when the affected part is difficult to tolerate, with another wet towel lid fire extinguishing flame.The affected part is warm disappear after, take away the towel of upper cover fire, drip on the surface, affected part once more and spread ethanol and light, so operate 3-4 time, be complete seance.1-2 days once, and 10 days is a course of treatment.
Chinese medicine is having its unique cognitive theory of medicine, abundant treatment means and excellent curative aspect the treatment knee joint osseous arthritis.
Adopt the auxiliary acupuncture cupping therapy of Chinese medicine; Be that to control with organic conception and dialectical opinion be theoretical basis, on the basic medical of needled conventionally cup, use Chinese medicine and act on the pathological changes Ashi point, have complementary advantages through remedying deficiency separately; The combination of inner and outside; Giving consideration to both the incidental and fundamental improves curative effect, has not only brought into play the useful effect of medicine but also has played the effect of acupuncture cupping.The unique analgesic effect that gets instant result is arranged.
Chinese medicine is assisted acupuncture cupping, and external application for curing is got and imitated soon, and effect is consolidated.Through the through sick institute of topical, stimulate local skin neural, vasodilation promotes drug absorption, improves the blood circulation in affected part, regulates the function in local muscle and joint.Make drug absorption more direct; Reach the effect of removing obstruction in the collateral to relieve pain, directly muscle and joint are played a role, the immunity of two-ways regulation body QI and blood; Microcirculation improvement and vascular function; Get rid of the harmful substance in the blood, and the benefit materials of body is in time added in the blood circulation go, impel body to rebulid homeostasis and recover normal physiological function.Excite intravital defense function, enhancing immunity.The untoward reaction of external therapy of Chinese herb knee joint osteoarthritis is few, and toleration is good, helps the absorption of medicine, and the swelling that effectively reduces inflammation improves joint deadlock in morning, alleviating pain and recovery function of joint.
This method adopts the conservative treatment of the reason of traditional Chinese medical science inner disease outer treat, and pure Chinese medicinal preparation has lowered the misery and the medical expense of doctor trained in Western medicine operation greatly, and this method does not absorb through gastrointestinal and Liver and kidney, so health is had no side effect, has stopped the generation of sequela, is difficult for recurrence.Easy to use, operation easily, no pain, cheap.Adopt that the auxiliary acupuncture cupping therapy order of Chinese medicine is local littlely to be had hemorrhagely, cup sucks 1-10ml mud shape or gluey blood coagulation again, and this method is the blood-letting puncture therapy that purifies the blood.This method have let out stop up poison, the meridian dredging, Shujin bone, the arteries and veins of invigorating blood circulation, the silt of reducing phlegm, QI and blood regulating, dispel the wind, the basic adaptive functions in cold expelling, dehumidifying, heat clearing away, adjusting joint, the effect such as go out of getting rid of evils.Can get final product rehabilitation through 3-5 times, the overwhelming majority can not recur in 5-10 years.
The specific embodiment
Said a kind of medicine of treating knee joint osteoarthritis is broken into 60 purpose powder with following raw material powder,
Cortex erythrinae 30g, Herba speranskiae tuberculatae 30g, Herba Lycopodii 30g, Cortex Acanthopancis 25g, Radix Clematidis 25g, Radix Angelicae Pubescentis 25g, Radix Aconiti 22g, Radix Aconiti Kusnezoffii 22g, triangular 17g, Olibanum 12g, Myrrha 12g, Radix Angelicae Sinensis 22g, Folium Artemisiae Argyi 30g.Then powder and 125ml rice vinegar are mixed into thick paste, can use.
Prepare 1 of 20ml disposable syringe, 95% medical alcohol 100ml, two of textile thick towels, 1 of hot water basin.
Method for using: with the thick paste medicine, stick in the kneecap joint or obvious sore place, medicine thickness is 1cm.Half basin hot water is put into towel, and taking-up is wrung out, and applies to cover on medicine.Press shallow ridges circlewise along 1cm place, medicine edge.Extract ethanol 20ml with syringe, drip along annular groove and inner surface and spread, light ethanol.Treat medicine heating when the affected part is difficult to tolerate, with another wet towel lid fire extinguishing flame.The affected part is warm disappear after, take away the towel of upper cover fire, drip on the surface, affected part once more and spread ethanol and light, so operate 3-4 time, be complete seance.1-2 days once, and 10 days is a course of treatment.
In order to verify the therapeutic effect of technical scheme of the present invention, the inventor has carried out clinical trial, and the result is following.
Pushing away the osteoarthritis diagnostic criteria of depositing in 1989 with reference to Americanism damp disease association judges; Following case is totally 100 examples, is divided into two groups.
50 examples are organized in treatment, male 22 examples, women 28 examples; 36 years old-73 years old age, 60 years old mean age; 2 months-11a of the course of disease, average 1.8a; Two knee joint 19 examples, single knee joint 31 examples; Recurrence after operation person 6 examples wherein.
Matched group 50 examples, male 27 examples, women 23 examples; 38 years old-70 years old age, average 58 years old; 2 months-11a of the course of disease, average 1.9 years; Single knee joint 32 examples, two knee joint 18 examples.
Two groups of patient's sexes, age, the course of disease, pathological changes, position have comparability through statistical procedures difference not statistically significant (p>0.05).
Criterion of therapeutical effect with reference to " new Chinese medicine clinical research guideline " traditional Chinese medical science knee joint osteoarthritis is judged.Recovery from illness: the clinical symptom disappearance joint movement function is normal.Produce effects: transference cure, joint movement function is unrestricted, the slight joint movement function mild limitation of symptom.Invalid: symptom and joint movement function do not have obvious improvement.
Two groups of clinical efficacies compare following table:
Group n Recovery from illness Produce effects Effectively Invalid Total effective rate %
The treatment group 50 29 13 7 1 98%
Matched group 50 16 14 11 9 82%
Compare with matched group, through X 2 test, p ﹤ 0.05, treatment group curative effect is superior to matched group.
According to Chinese medical theory and the meticulous prescription of clinical experience: Cortex erythrinae, Herba speranskiae tuberculatae, Herba Lycopodii, Radix Clematidis, Cortex Acanthopancis, Radix Aconiti, Radix Aconiti Kusnezoffii, cold, the dehumidifying detumescence of wind expelling powder of levisticum; Collateral dredging relieves the pain; Can diminish inflammation, regulate the immunologic function and the metabolism in kneecap joint.Radix Clematidis, Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Angelicae Pubescentis, Folium Artemisiae Argyi temperature three-way meridian, the diffusing muscles and bones numbness poison of a surname have the antiinflammatory detumescent, improve the microcirculation in kneecap joint.Cortex Acanthopancis, Radix Angelicae Sinensis temperature compensation Liver and kidney, nourshing blood and promoting blood circulation, strong muscles and bones, muscles and bones are good for, cold-damp is gone, pain is ended certainly.Triangular, Olibanum, Myrrha, rice vinegar removing mass blood, circulation of qi promoting stagnate, blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, softening sclerotin, the blood oxygen supply that the QI and blood circulation is unimpeded, increased the kneecap joint.
Fire is treated and is cooperated the local drug of topical application, can make the knee skin mucosa congested, and the pore expansion is that effective ingredient fully infiltrates into pathological tissues; But fire treatment and drug synergism accelerate blood and lymph fluid circulation, warm promoting blood circulation, blood circulation promoting and blood stasis dispelling, a surname's dispersing wind and cold; Eliminate rheumatism numbness poison, reduce intraosseous pressure, remove the long-pending metabolite of the stasis of blood; Reach the QI and blood that the dredging the meridian stasis of blood stagnates, alleviating pain and swelling improve the purpose of kneecap function of joint.
Example 1, old XX, man, 56 years old, first visit on August 26 in 2007.Patient's fatigue before 4 years double knee joint pain behind the cold water of holding concurrently, to stand up or painful heavy during stair activity, movable unfavorable, making a sound in the joint, can not do the action of turning round, and increases the weight of gradually especially, and arthroncus can not be squatted down, and the warm aversion to cold of happiness meets that cold-damp is overcast and rainy to be increased the weight of.The knee joint X-ray film shows: the joint space narrows down, and articular surface is uneven, densification, and the edge is lip appearance, sudden change point between condyle, the patella inner edge is fine and close, and irregular vegetation is arranged.Examine and be knee joint osseous arthritis, belong to deficiency of the liver and kindey, the resistance of the blood network stasis of blood, cold-damp is detained.Treat 10d with this method, double knee joint swells to ache and disappears basically, and activity has not had obvious obstacle, continues treatment 10d and consolidates curative effect, follows up a case by regular visits to and does not have recurrence so far.
Example 2, Liu XX, the woman, 43 years old, on May 18th, 2006 went to a doctor.Patient's influence work of single gonalgia several years and life, sx over nearly two months and going to a doctor, disease is seen single knee joint swelling, can not squat down, and is movable unfavorable, increases the weight of activity knee joint audible and friction sound gradually.X-ray film shows: knee epiphysis edge has hyperosteogeny to form.Examine and be knee osteoarthritis.Etiology and pathogenesis is a deficiency of the liver and kindey, diseases caused by exogenous pathogenic factor cold-damp, blockage of meridian.The suitable temperature compensation Liver and kidney of method of treatment, expelling wind and cold, promoting blood circulation to remove obstruction in the collateral.Give above-mentioned prescription drug treatment.State all diseases behind the 10d and subtract greatly, not anti-recurrence is abide by the law and is treated 10d, all disease recoveries from illness.In the past few years do not see recurrence.
Lee XX, the woman, the left gonalgia 1 year is surplus, recently sx and going to a doctor.Have a medical check-up: ordinary circumstance is good, and left knee joint swelling is pressed around dark face of patella and the joint and ached, the joint motion mild limitation, and cold, moist pain is heavier.X-ray film shows: lower edge, spinous process of tibia, hyperosteogeny form on the patella, and the joint space narrows down.Be diagnosed as left knee joint osseous arthritis.With the treatment of above-mentioned prescription drug, 5 times, swollen painful basic disappearance of knee joint, movable no much obstacles continue with above prescription 10 days, at the disease releasing, do not have 2 years more recurrence is arranged.

Claims (4)

1. a medicine of treating knee joint osteoarthritis is characterized in that, by following preparation of raw material,
Cortex erythrinae 25-35g, Herba speranskiae tuberculatae 25-35g, Herba Lycopodii 25-35g, Cortex Acanthopancis 20-30g, Radix Clematidis 20-30g, Radix Angelicae Pubescentis 20-30g, Radix Aconiti 18-25g, Radix Aconiti Kusnezoffii 18-25g, triangular 15-20g, Olibanum 10-15g, Myrrha 10-15g, Radix Angelicae Sinensis 20-25g, Folium Artemisiae Argyi 25-35g, rice vinegar 100-150ml.
2. according to the said a kind of medicine of treating knee joint osteoarthritis of claim 1, it is characterized in that, by following preparation of raw material,
Cortex erythrinae 28-32g, Herba speranskiae tuberculatae 28-32g, Herba Lycopodii 28-32g, Cortex Acanthopancis 24-26g, Radix Clematidis 24-26g, Radix Angelicae Pubescentis 24-26g, Radix Aconiti 21-23g, Radix Aconiti Kusnezoffii 21-23g, triangular 16-18g, Olibanum 12-13g, Myrrha 12-13g, Radix Angelicae Sinensis 22-23g, Folium Artemisiae Argyi 27-32g, rice vinegar 120-130ml.
3. according to the said a kind of medicine of treating knee joint osteoarthritis of claim 1, it is characterized in that, by following preparation of raw material,
Cortex erythrinae 30g, Herba speranskiae tuberculatae 30g, Herba Lycopodii 30g, Cortex Acanthopancis 25g, Radix Clematidis 25g, Radix Angelicae Pubescentis 25g, Radix Aconiti 22g, Radix Aconiti Kusnezoffii 22g, triangular 17g, Olibanum 12g, Myrrha 12g, Radix Angelicae Sinensis 22g, Folium Artemisiae Argyi 30g, rice vinegar 125ml.
4. a method for preparing of treating the knee joint osteoarthritis medicine is characterized in that,
1) according to the proportion relation preparation raw material: Cortex erythrinae, Herba speranskiae tuberculatae, Herba Lycopodii, Cortex Acanthopancis, Radix Clematidis, Radix Angelicae Pubescentis, Radix Aconiti, Radix Aconiti Kusnezoffii, triangular, Olibanum, Myrrha, Radix Angelicae Sinensis, Folium Artemisiae Argyi;
2), become 60 purpose powder with the raw material pulverizing for preparing;
3) with powder and rice vinegar mix homogeneously, can use.
CN2011103371298A 2011-10-31 2011-10-31 Medicine used for treating knee osteoarthritis, and preparation method thereof Pending CN102362997A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526172A (en) * 2012-03-21 2012-07-04 河南省洛正制药厂 Chinese medicinal bagged soaking agent for treating joint numbness pain and preparation method thereof
CN103417599A (en) * 2013-08-27 2013-12-04 桂林安和药业有限公司 Soft plaster substrate prepared from traditional Chinese medicine ingredients and preparation method thereof
CN105106339A (en) * 2015-08-05 2015-12-02 李武 Pharmaceutical for treating degenerative knee osteoarthritis and preparation method thereof
CN105596558A (en) * 2016-01-29 2016-05-25 兰州存仁风湿病研究院 Cold expelling and pain easing powder and using method thereof
CN105687716A (en) * 2016-04-02 2016-06-22 吴仕峰 Traditional Chinese medicine preparation for treating knee joint osteoarthritis and preparation method thereof
CN105943719A (en) * 2016-04-28 2016-09-21 谭永胜 Externally-applied Chinese herbal medicine and preparation method thereof
CN108310327A (en) * 2018-05-03 2018-07-24 陕西刘氏臻芝堂健康管理有限公司 A kind of health true strength heat treasured and preparation method thereof

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CN101905007A (en) * 2010-07-09 2010-12-08 徐利华 Plaster for curing rheumatoid pains in neck, shoulders, waist and legs

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526172A (en) * 2012-03-21 2012-07-04 河南省洛正制药厂 Chinese medicinal bagged soaking agent for treating joint numbness pain and preparation method thereof
CN103417599A (en) * 2013-08-27 2013-12-04 桂林安和药业有限公司 Soft plaster substrate prepared from traditional Chinese medicine ingredients and preparation method thereof
CN103417599B (en) * 2013-08-27 2015-04-22 桂林安和药业有限公司 Soft plaster substrate prepared from traditional Chinese medicine ingredients and preparation method thereof
CN105106339A (en) * 2015-08-05 2015-12-02 李武 Pharmaceutical for treating degenerative knee osteoarthritis and preparation method thereof
CN105596558A (en) * 2016-01-29 2016-05-25 兰州存仁风湿病研究院 Cold expelling and pain easing powder and using method thereof
CN105687716A (en) * 2016-04-02 2016-06-22 吴仕峰 Traditional Chinese medicine preparation for treating knee joint osteoarthritis and preparation method thereof
CN105943719A (en) * 2016-04-28 2016-09-21 谭永胜 Externally-applied Chinese herbal medicine and preparation method thereof
CN108310327A (en) * 2018-05-03 2018-07-24 陕西刘氏臻芝堂健康管理有限公司 A kind of health true strength heat treasured and preparation method thereof

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Application publication date: 20120229