CN103417433B - Whitening and freckle-removing cream with whitening and freckle-removing functions, production technology of cream, and nitrogen filling machine - Google Patents
Whitening and freckle-removing cream with whitening and freckle-removing functions, production technology of cream, and nitrogen filling machine Download PDFInfo
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- CN103417433B CN103417433B CN201310338208.XA CN201310338208A CN103417433B CN 103417433 B CN103417433 B CN 103417433B CN 201310338208 A CN201310338208 A CN 201310338208A CN 103417433 B CN103417433 B CN 103417433B
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- whitening
- freckle
- cream
- eliminating cream
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 title claims abstract description 86
- 230000002087 whitening effect Effects 0.000 title claims abstract description 79
- 239000006071 cream Substances 0.000 title claims abstract description 50
- 229910052757 nitrogen Inorganic materials 0.000 title claims abstract description 42
- 238000011049 filling Methods 0.000 title claims abstract description 32
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 18
- 238000005516 engineering process Methods 0.000 title claims abstract description 16
- 208000003351 Melanosis Diseases 0.000 title abstract description 8
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 43
- 239000000463 material Substances 0.000 claims abstract description 42
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 claims abstract description 36
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 22
- 229960003471 retinol Drugs 0.000 claims abstract description 21
- 235000020944 retinol Nutrition 0.000 claims abstract description 21
- 239000011607 retinol Substances 0.000 claims abstract description 21
- 239000002502 liposome Substances 0.000 claims abstract description 20
- OEWBEINAQKIQLZ-CMRBMDBWSA-N [(2s)-2-[(2r)-3,4-bis(2-hexyldecanoyloxy)-5-oxo-2h-furan-2-yl]-2-(2-hexyldecanoyloxy)ethyl] 2-hexyldecanoate Chemical compound CCCCCCCCC(CCCCCC)C(=O)OC[C@H](OC(=O)C(CCCCCC)CCCCCCCC)[C@H]1OC(=O)C(OC(=O)C(CCCCCC)CCCCCCCC)=C1OC(=O)C(CCCCCC)CCCCCCCC OEWBEINAQKIQLZ-CMRBMDBWSA-N 0.000 claims abstract description 18
- 229940108325 retinyl palmitate Drugs 0.000 claims abstract description 18
- 239000011769 retinyl palmitate Substances 0.000 claims abstract description 18
- 235000019172 retinyl palmitate Nutrition 0.000 claims abstract description 18
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 36
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 36
- 239000012071 phase Substances 0.000 claims description 27
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 24
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims description 24
- 229940081733 cetearyl alcohol Drugs 0.000 claims description 24
- 239000000203 mixture Substances 0.000 claims description 24
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 24
- 150000001875 compounds Chemical class 0.000 claims description 22
- 241000208681 Hamamelis virginiana Species 0.000 claims description 16
- 239000000047 product Substances 0.000 claims description 16
- 238000007789 sealing Methods 0.000 claims description 16
- 239000011265 semifinished product Substances 0.000 claims description 15
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 12
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims description 12
- 239000004322 Butylated hydroxytoluene Substances 0.000 claims description 12
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 12
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
- OQILCOQZDHPEAZ-UHFFFAOYSA-N Palmitinsaeure-octylester Natural products CCCCCCCCCCCCCCCC(=O)OCCCCCCCC OQILCOQZDHPEAZ-UHFFFAOYSA-N 0.000 claims description 12
- 229960000458 allantoin Drugs 0.000 claims description 12
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 12
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- 235000010354 butylated hydroxytoluene Nutrition 0.000 claims description 12
- 229940086555 cyclomethicone Drugs 0.000 claims description 12
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 12
- PKPOVTYZGGYDIJ-UHFFFAOYSA-N dioctyl carbonate Chemical compound CCCCCCCCOC(=O)OCCCCCCCC PKPOVTYZGGYDIJ-UHFFFAOYSA-N 0.000 claims description 12
- WSDISUOETYTPRL-UHFFFAOYSA-N dmdm hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 claims description 12
- GJQLBGWSDGMZKM-UHFFFAOYSA-N ethylhexyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(CC)CCCCC GJQLBGWSDGMZKM-UHFFFAOYSA-N 0.000 claims description 12
- 229910052740 iodine Inorganic materials 0.000 claims description 12
- 239000011630 iodine Substances 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 12
- KRPAJLYSLFNDOA-UHFFFAOYSA-N mephenesin carbamate Chemical compound CC1=CC=CC=C1OCC(O)COC(N)=O KRPAJLYSLFNDOA-UHFFFAOYSA-N 0.000 claims description 12
- 229950006838 mephenesin carbamate Drugs 0.000 claims description 12
- FBUKVWPVBMHYJY-UHFFFAOYSA-M nonanoate Chemical compound CCCCCCCCC([O-])=O FBUKVWPVBMHYJY-UHFFFAOYSA-M 0.000 claims description 12
- 239000004006 olive oil Substances 0.000 claims description 12
- 235000008390 olive oil Nutrition 0.000 claims description 12
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 claims description 12
- 239000004408 titanium dioxide Substances 0.000 claims description 12
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- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 12
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 11
- 238000013019 agitation Methods 0.000 claims description 11
- 239000000787 lecithin Substances 0.000 claims description 11
- 229940067606 lecithin Drugs 0.000 claims description 11
- 235000010445 lecithin Nutrition 0.000 claims description 11
- 239000008367 deionised water Substances 0.000 claims description 9
- 229910021641 deionized water Inorganic materials 0.000 claims description 9
- 239000003921 oil Substances 0.000 claims description 9
- 235000019198 oils Nutrition 0.000 claims description 9
- 239000008346 aqueous phase Substances 0.000 claims description 6
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- 238000010438 heat treatment Methods 0.000 claims description 6
- -1 stereth-2 Chemical compound 0.000 claims description 6
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 4
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- 241000208680 Hamamelis mollis Species 0.000 abstract 1
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 6
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- 229940082431 hamamelis virginiana leaf extract Drugs 0.000 description 5
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
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- 239000001301 oxygen Substances 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 3
- 229930003268 Vitamin C Natural products 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 3
- 238000003556 assay Methods 0.000 description 3
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- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
- 241001597008 Nomeidae Species 0.000 description 1
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- 102000003425 Tyrosinase Human genes 0.000 description 1
- 108060008724 Tyrosinase Proteins 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
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- Cosmetics (AREA)
Abstract
The invention relates to a whitening and freckle-removing cream with whitening and freckle-removing functions, a production technology of the cream and a nitrogen filling machine, and aims to prepare a cosmetic with better whitening and freckle-removing efficacies and without any irritant and toxic side effects as well as provide equipment which can prolong the quality guarantee period of the cosmetic. The invention adopts the technical scheme as follows: the whitening and freckle-removing cream added with whitening and freckle-removing composite raw materials comprises a witch hazel extract, ascorbyl tetraisopalmitate, retinyl palmitate, liposome-coated retinol and other raw materials. The production technology comprises the following steps: 1) mixing a plurality of raw materials into an oil-phase composite solution; 2) mixing a plurality of raw materials into a water-phase composite solution; 3) mixing and homogenizing the two composite solutions; 4) adding a plurality of raw materials, and homogenizing; 5) filling nitrogen, and performing endcapping to obtain a product. A filling assembly of a nitrogen filling and endcapping machine comprises an injecting barrel, an inner material filling joint, a nitrogen filling joint and an exhausting joint, and is provided with an electromagnetic valve controlled by a PLC controller.
Description
Technical field
What the present invention relates to a kind of whitening and spot eliminating cream, the production technology of whitening and spot eliminating cream and production whitening and spot eliminating cream fills nitrogen conduit loading tail sealing machine.
Background technology
When ultraviolet radiation skin, the chromoplast being arranged in stratum basale can secrete a kind of Mai Laning pigment, and the activity that it can activate tryrosinase makes the tyrosine in tryrosinase and blood react thus generates melanin.Melanin effectively can absorb ultraviolet, and protection human body is from ultraviolet injury.If but after melanin do not excrete by body metabolism, will remain in epidermal area and form pigmented spots (comprising freckle, sunburn, black speck etc.), affect very much the aesthetic feeling of face.
And in the production process of whitening class cosmetics (being generally emulsifiable paste shape with gluey), usually use flexible pipe loading equipment to carry out fill sealing.But owing to being subject to equipment restriction, during fill, cosmetics are very easily mixed into air, the oxygen after depositing a period of time in air can make cosmetics occur jaundice denaturalization phenomenon, greatly have impact on product quality.
Summary of the invention
The object of the invention is to overcome the deficiency in above-mentioned background technology, what provide a kind of whitening and spot eliminating cream, production technology and production whitening and spot eliminating cream of adding whitening and speckle dispelling compound material respectively fills nitrogen conduit loading tail sealing machine; This product and production technology thereof should be able to be produced a kind ofly has better whitening effect and to the cosmetics of skin without any zest and toxic and side effects; This equipment should be able to make cosmetics avoid contacting with air thus extend the quality guarantee period of cosmetics.
Technical scheme provided by the invention is: a kind of whitening and spot eliminating cream of adding whitening and speckle dispelling compound material, it is characterized in that this whitening and spot eliminating cream comprises following component and weight portion: propylene glycol 5.0 ~ 10.0%, ethylhexyl palmitate 5.0 ~ 8.0%, Cyclomethicone 4.0 ~ 6.0%, stereth-23.0 ~ 4.0%, cetearyl alcohol 3.0 ~ 4.0%, Parleam 3.0 ~ 4.0%, stereth-212.0 ~ 2.5%, the different pelargonate 2.0 ~ 2.5% of cetearyl alcohol, olive oil 1.0 ~ 1.5%, dicaprylyl carbonate 1.0 ~ 1.5%, titanium dioxide 1.0 ~ 1.5%, AVC 0.3 ~ 0.6%, Ascorbyl Tetraisopalmitate 0.3 ~ 0.5%, allantoin 0.1 ~ 0.2%, citric acid 0.1 ~ 0.2%, tocopherol acetas 0.1 ~ 0.2%, lecithin 0.1 ~ 0.2%, butylated hydroxytoluene 0.1 ~ 0.2%, retinyl palmitate 0.1 ~ 0.15%, EDETATE SODIUM 0.05 ~ 0.1%, Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract 0.05 ~ 0.10%, DMDM Hydantoin 0.05 ~ 0.10%, iodine propilolic alcohol butyl mephenesin Carbamate 0.01 ~ 0.04%, essence 0.03 ~ 0.05%, the coated retinol 0.02 ~ 0.05% of liposomes, all the other are deionized waters, whitening and speckle dispelling compound material (the coated retinol of Ascorbyl Tetraisopalmitate, retinyl palmitate and liposomes) content is wherein 0.42 ~ 0.7%.
Add a whitening and spot eliminating cream for whitening and speckle dispelling compound material, it is characterized in that this whitening and spot eliminating cream comprises following component and weight portion: propylene glycol 5.0 ~ 10.0%, ethylhexyl palmitate 5.0 ~ 8.0%, Cyclomethicone 4.0 ~ 6.0%, stereth-23.0 ~ 4.0%, cetearyl alcohol 3.0 ~ 4.0%, Parleam 3.0 ~ 4.0%, stereth-212.0 ~ 2.5%, the different pelargonate 2.0 ~ 2.5% of cetearyl alcohol, olive oil 1.0 ~ 1.5%, dicaprylyl carbonate 1.0 ~ 1.5%, titanium dioxide 1.0 ~ 1.5%, AVC 0.3 ~ 0.6%, Ascorbyl Tetraisopalmitate 0.25 ~ 0.45%, allantoin 0.1 ~ 0.2%, citric acid 0.1 ~ 0.2%, tocopherol acetas 0.1 ~ 0.2%, lecithin 0.1 ~ 0.2%, butylated hydroxytoluene 0.1 ~ 0.2%, retinyl palmitate 0.05 ~ 0.10%, EDETATE SODIUM 0.05 ~ 0.1%, Hamamelis virginiana leaf extract 0.05 ~ 0.10%, DMDM Hydantoin 0.05 ~ 0.10%, iodine propilolic alcohol butyl mephenesin Carbamate 0.01 ~ 0.04%, essence 0.03 ~ 0.05%, the coated retinol 0.01 ~ 0.03% of liposomes, all the other are deionized waters, whitening and speckle dispelling compound material (the coated retinol of Ascorbyl Tetraisopalmitate, retinyl palmitate and liposomes) content is wherein 0.31 ~ 0.58%.
A kind of whitening and spot eliminating cream of adding whitening and speckle dispelling compound material, it is characterized in that this whitening and spot eliminating cream comprises following component and weight portion: propylene glycol 6.0%, ethylhexyl palmitate 5.5%, Cyclomethicone 4.0%, stereth-23.0%, cetearyl alcohol 3.0%, Parleam 3.0%, stereth-212.0%, the different pelargonate 2.0% of cetearyl alcohol, olive oil 1.0%, dicaprylyl carbonate 1.0%, titanium dioxide 1.0%, AVC 0.4%, Ascorbyl Tetraisopalmitate 0.4%, allantoin 0.2%, citric acid 0.1%, tocopherol acetas 0.1%, lecithin 0.1%, butylated hydroxytoluene 0.1%, retinyl palmitate 0.10%, EDETATE SODIUM 0.05%, Hamamelis virginiana leaf extract 0.05%, DMDM Hydantoin 0.05%, iodine propilolic alcohol butyl mephenesin Carbamate 0.01%, essence 0.05%, the coated retinol 0.02% of liposomes, all the other are deionized waters, whitening and speckle dispelling compound material (the coated retinol of Ascorbyl Tetraisopalmitate, retinyl palmitate and liposomes) content is wherein 0.52%, is optimal proportion.
Add a production technology for the whitening and spot eliminating cream of whitening and speckle dispelling compound material, comprise the following steps:
1) by ethylhexyl palmitate, Cyclomethicone, stereth-2, cetearyl alcohol, Parleam, stereth-21, the different pelargonate of cetearyl alcohol, olive oil, dicaprylyl carbonate, titanium dioxide, Ascorbyl Tetraisopalmitate, tocopherol acetas, butylated hydroxytoluene, lecithin, retinyl palmitate mix and blend heating for dissolving, temperature control becomes oil phase combination liquid at 70-80 DEG C;
2) by propylene glycol, AVC, allantoin, citric acid, EDETATE SODIUM, deionized water mix and blend heating for dissolving, temperature control becomes aqueous phase combination liquid at 80-90 DEG C;
3) oil phase is combined liquid to pour in aqueous phase combination liquid, after homogenizing, Keep agitation cools;
4) in the semi-finished product that previous step is obtained, Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract, DMDM Hydantoin, iodine propilolic alcohol butyl mephenesin Carbamate, essence, the coated retinol of liposomes is added, evacuation after homogenizing is also cooled to less than 35 DEG C, obtains the semi-finished product of whitening and spot eliminating cream;
5) semi-finished product of whitening and spot eliminating cream are obtained whitening and spot eliminating cream finished product after filling nitrogen fill sealing.
Namely rev/min rotating speed in described step 3) during homogenizing is 2500-3500RPM(Revolutions Per Minute) and the time be 4-6 minute, after cooling, temperature is 42-48 DEG C.
Homogenizing process in described step 4) is: first stir 0.5-1.5 minute when rotating speed is 2500-3500RPM, then rotating speed is reduced to 800-1200RPM and evacuation from 0 to-0.1Mpa, Keep agitation is cooled to less than 35 degrees Celsius.
A kind of produce whitening and spot eliminating cream fill nitrogen conduit loading tail sealing machine, filling components wherein comprises material feeding bucket, be arranged on to be connected below material feeding bucket and with material feeding bottom of the barrel in expect filling adaptor, it is characterized in that: described interior material filling adaptor is also arranged side by side be connected with storage nitrogen equipment fill nitrogen joint and for derive air exhaust joint; Described interior material filling adaptor nitrogen joint is equipped with electromagnetic valve and all electromagnetic valves are all connected with PLC with filling.
The described nitrogen joint that fills is connected with storage nitrogen equipment by flexible pipe.
Described exhaust joint is by trachea and extraneous conducting.
Described nitrogen storage equipment is nitrogen cylinder.
The invention has the beneficial effects as follows:
1, whitening and speckle dispelling compound material (comprising Ascorbyl Tetraisopalmitate, retinyl palmitate, the coated retinol of liposomes) is added with in the whitening and spot eliminating cream in the present invention; Ascorbyl Tetraisopalmitate and retinyl palmitate are fat soluble vitamin C derivant, free vitamin C can be resolved into after being absorbed by the skin, free vitamin C can suppress the activity of Tyrosinase, thus avoids melanic generation and stimulation collagen hypertrophy to desalinate microgroove; And the liposomes carrier in the coated retinol of liposomes can enter in horny layer and discharges retinol, reach and accelerate cutin metabolism and desalination pigmented spots effect;
Therefore, this whitening and spot eliminating cream product has good whitening and speckle dispelling effect, can effectively desalinate skin pigment spot and microgroove, skin health is become clear, and this product without any zest and toxic and side effects to skin, is suitable for any ages and uses (senile plaque especially for older person has better effect).
2, the production technology provided can guarantee the quality of whitening and spot eliminating cream, and production efficiency is higher.
Filling in nitrogen conduit loading tail sealing machine 3, in the present invention has additional nitrogen charging device, by pouring into nitrogen in advance to discharge the air in product when fill, avoids product to occur oxidation deterioration, the activity of QUBAN SHUANG of can effectively staying pale when long-time preservation.
Accompanying drawing explanation
Fig. 1 is the main TV structure schematic diagram filling nitrogen conduit loading tail sealing machine in the present invention.
Fig. 2 is the structure for amplifying schematic diagram in A portion in Fig. 1.
Detailed description of the invention
The coated retinol of liposomes of the present invention (retinol and vitamin A), directly buys (see the said firm's product description) from German ROVI COSMETICS company.
Hamamelis virginiana leaf extract of the present invention, directly buys (see the said firm's product description from Taiwan Wei Heng Industry Co., Ltd; Description name is called " Radix Hamamelidis Mollis extraction ").
Below in conjunction with non-limiting examples, the whitening and spot eliminating cream of adding whitening and speckle dispelling compound material is described further.
Embodiment 1
Get propylene glycol 5.0Kg, ethylhexyl palmitate 5.0Kg, Cyclomethicone 4.0Kg, stereth-23.0Kg, cetearyl alcohol 3.0Kg, Parleam 3.0Kg, stereth-212.0Kg, the different pelargonate 2.0Kg of cetearyl alcohol, olive oil 1.0Kg, dicaprylyl carbonate 1.0Kg, titanium dioxide 1.0Kg, AVC 0.3Kg, Ascorbyl Tetraisopalmitate 0.3Kg, allantoin 0.1Kg, citric acid 0.1Kg, tocopherol acetas 0.1Kg, lecithin 0.1Kg, butylated hydroxytoluene 0.1Kg, retinyl palmitate 0.1Kg, EDETATE SODIUM 0.05Kg, Hamamelis virginiana leaf extract 0.05Kg, DMDM Hydantoin 0.05Kg, iodine propilolic alcohol butyl mephenesin Carbamate 0.01Kg, essence 0.03Kg, the coated retinol 0.02Kg of liposomes, surplus is deionized water 68.59Kg.
1) oil phase component ethylhexyl palmitate, Cyclomethicone, stereth-2, cetearyl alcohol, Parleam, stereth-21, the different pelargonate of cetearyl alcohol, olive oil, dicaprylyl carbonate, titanium dioxide, Ascorbyl Tetraisopalmitate, tocopherol acetas, butylated hydroxytoluene, lecithin, retinyl palmitate mix and blend are heated to all dissolve without after granule by formula ratio, temperature control to 75 is DEG C for subsequent use:
2) water phase components propylene glycol, AVC, allantoin, citric acid, EDETATE SODIUM, deionized water mix and blend are heated to all dissolve without after granule, temperature control to 85 is DEG C for subsequent use:
3) after A with B phase completes, pour A phase into B phase, homogenizing adjustment of rotational speed to 3,000RPM, homogenizing 5 minutes, Keep agitation cooling obtains C phase:
4) when C phase temperature is down to 45 DEG C, active adding ingredient Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract, DMDM Hydantoin, iodine propilolic alcohol butyl mephenesin Carbamate, essence, the coated retinol of liposomes are added, by homogenizing adjustment of rotational speed to 3,000RPM, time 1Mins, after completing this step, adjustment mixing speed to 1,000RPM, evacuation is from 0 to-0.1Mpa, and Keep agitation is cooled to less than 35 DEG C, again by negative pressure transportation discharging, a kind of whitening and spot eliminating cream semi-finished product for standby of adding whitening and speckle dispelling compound material:
5) a kind of whitening and spot eliminating cream semi-finished product physical and chemical index adding whitening and speckle dispelling compound material is treated after the assay was approved, through Full automatic soft pipe conduit loading tail sealing machine, by PLC Controlling solenoid valve, realize every plastic-aluminum flexible pipe and be filled with inert nitrogen gas before filling the container, inflated with nitrogen interface 8MM diameter, interface 2MM diameter of giving vent to anger, inflated with nitrogen pressure is at more than 0.4MP, utilize specific gravity of gas different, discharged by oxygen, namely fill obtains whitening and spot eliminating cream finished product.
Embodiment 2
Get propylene glycol 10.0Kg, ethylhexyl palmitate 8.0Kg, Cyclomethicone 6.0Kg, stereth-24.0Kg, cetearyl alcohol 4.0Kg, Parleam 4.0Kg, stereth-212.5Kg, the different pelargonate 2.5Kg of cetearyl alcohol, olive oil 1.5Kg, dicaprylyl carbonate 1.5Kg, titanium dioxide 1.5Kg, AVC 0.6Kg, Ascorbyl Tetraisopalmitate 0.5Kg, allantoin 0.2Kg, citric acid 0.2Kg, tocopherol acetas 0.2Kg, lecithin 0.2Kg, butylated hydroxytoluene 0.2Kg, retinyl palmitate 0.15Kg, EDETATE SODIUM 0.1Kg, Hamamelis virginiana leaf extract 0.10Kg, DMDM Hydantoin 0.10Kg, iodine propilolic alcohol butyl mephenesin Carbamate 0.04Kg, essence 0.05Kg, the coated retinol 0.05Kg of liposomes, deionized water 51.81Kg.
1) oil phase component ethylhexyl palmitate, Cyclomethicone, stereth-2, cetearyl alcohol, Parleam, stereth-21, the different pelargonate of cetearyl alcohol, olive oil, dicaprylyl carbonate, titanium dioxide, Ascorbyl Tetraisopalmitate, tocopherol acetas, butylated hydroxytoluene, lecithin, retinyl palmitate mix and blend are heated to all dissolve without after granule by formula ratio, temperature control to 75 is DEG C for subsequent use:
2) water phase components propylene glycol, AVC, allantoin, citric acid, EDETATE SODIUM, deionized water mix and blend are heated to all dissolve without after granule, temperature control to 85 is DEG C for subsequent use:
3) after A with B phase completes, pour A phase into B phase, homogenizing adjustment of rotational speed to 3,000RPM, homogenizing 5 minutes, Keep agitation cooling obtains C phase:
4) when C phase temperature is down to 45 DEG C, active adding ingredient Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract, DMDM Hydantoin, iodine propilolic alcohol butyl mephenesin Carbamate, essence, the coated retinol of liposomes are added, by homogenizing adjustment of rotational speed to 3,000RPM, time 1Mins, after completing this step, adjustment mixing speed to 1,000RPM, evacuation is from 0 to-0.1Mpa, and Keep agitation is cooled to less than 35 DEG C, again by negative pressure transportation discharging, a kind of whitening and spot eliminating cream semi-finished product for standby of adding whitening and speckle dispelling compound material:
5) a kind of whitening and spot eliminating cream semi-finished product physical and chemical index adding whitening and speckle dispelling compound material is treated after the assay was approved, through Full automatic soft pipe conduit loading tail sealing machine, by PLC Controlling solenoid valve, realize every plastic-aluminum flexible pipe and be filled with inert nitrogen gas before filling the container, inflated with nitrogen interface 8MM diameter, interface 2MM diameter of giving vent to anger, inflated with nitrogen pressure is at more than 0.4MP, utilize specific gravity of gas different, discharged by oxygen, namely fill obtains whitening and spot eliminating cream finished product.
Embodiment 3
Get propylene glycol 6.0Kg, ethylhexyl palmitate 5.5Kg, Cyclomethicone 4.0Kg, stereth-23.0Kg, cetearyl alcohol 3.0Kg, Parleam 3.0Kg, stereth-212.0Kg, the different pelargonate 2.0Kg of cetearyl alcohol, olive oil 1.0Kg, dicaprylyl carbonate 1.0Kg, titanium dioxide 1.0Kg, AVC 0.4Kg, allantoin 0.2Kg, citric acid 0.1Kg, tocopherol acetas 0.1Kg, lecithin 0.1Kg, butylated hydroxytoluene 0.1Kg, EDETATE SODIUM 0.05Kg, Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract 0.05Kg, DMDM Hydantoin 0.05Kg, iodine propilolic alcohol butyl mephenesin Carbamate 0.03Kg, essence 0.05Kg, Ascorbyl Tetraisopalmitate 0.4Kg, retinyl palmitate 0.10Kg, the coated retinol 0.02Kg of liposomes, deionized water 66.73Kg.
1) oil phase component ethylhexyl palmitate, Cyclomethicone, stereth-2, cetearyl alcohol, Parleam, stereth-21, the different pelargonate of cetearyl alcohol, olive oil, dicaprylyl carbonate, titanium dioxide, Ascorbyl Tetraisopalmitate, tocopherol acetas, butylated hydroxytoluene, lecithin, retinyl palmitate mix and blend are heated to all dissolve without after granule by formula ratio, temperature control to 70 is DEG C for subsequent use:
2) water phase components propylene glycol, AVC, allantoin, citric acid, EDETATE SODIUM, deionized water mix and blend are heated to all dissolve without after granule, temperature control to 80 is DEG C for subsequent use:
3) after A with B phase completes, pour A phase into B phase, homogenizing adjustment of rotational speed to 3,000RPM, homogenizing 5 minutes, Keep agitation cooling obtains C phase:
4) when C phase temperature is down to 45 DEG C, active adding ingredient Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract, DMDM Hydantoin, iodine propilolic alcohol butyl mephenesin Carbamate, essence, the coated retinol of liposomes are added, by homogenizing adjustment of rotational speed to 3,000RPM, time 1Mins, after completing this step, adjustment mixing speed to 1,000RPM, evacuation is from 0 to-0.1Mpa, and Keep agitation is cooled to 33 DEG C, again by negative pressure transportation discharging, a kind of whitening and spot eliminating cream semi-finished product for standby of adding whitening and speckle dispelling compound material:
5) this whitening and spot eliminating cream semi-finished product physical and chemical index is treated after the assay was approved, through Full automatic soft pipe conduit loading tail sealing machine, by PLC Controlling solenoid valve, realize every plastic-aluminum flexible pipe and be filled with inert nitrogen gas before filling the container, inflated with nitrogen interface 8MM diameter, interface 2MM diameter of giving vent to anger, inflated with nitrogen pressure is at more than 0.4MP, utilize specific gravity of gas different, discharged by oxygen, namely fill obtains whitening and spot eliminating cream finished product.
For understanding result of use of the present invention, with the form of questionnaire survey, investigation on probation is widely carried out to this product, men and women trier 250 people in all parts of the country is included in this investigation altogether in, wherein male 110 people, women 140 people, the oldest 58 years old, minimum 30 years old, mean age one's mid-40s, regains effective questionnaire 190 parts altogether.
190 triers use a kind of whitening and spot eliminating cream of adding whitening and speckle dispelling compound material as follows to the result of the indices degree self evaluation that whitening and speckle dispelling is correlated with after 3 months:
Reduce pore fineness: have the trier of 30% and 55% have moderate to improve and obviously improve respectively;
Promote skin lightness: have the trier of 40% and 70% have moderate to improve and obviously improve respectively;
Desalination skin speckle amount: have the trier of 50% and 75% have moderate to improve and obviously improve respectively;
Reduce skin lines amount: have the trier of 45% and 50% have moderate to improve and obviously improve respectively;
As can be seen from the result of the self assessment of trier, this product to reduce pore careful, promote skin and become clear, desalinate skin speckle, reduce skin lines and have improvement in various degree.Show according to survey result: the whitening and spot eliminating cream of this interpolation whitening and speckle dispelling compound material has desalination skin speckle and microgroove effect preferably.
Below in conjunction with non-limiting examples, a kind of production technology of adding the whitening and spot eliminating cream of whitening and speckle dispelling compound material is described further.
Add a production technology for the whitening and spot eliminating cream of whitening and speckle dispelling compound material, comprise the following steps:
1) by ethylhexyl palmitate, Cyclomethicone, stereth-2, cetearyl alcohol, Parleam, stereth-21, the different pelargonate of cetearyl alcohol, olive oil, dicaprylyl carbonate, titanium dioxide, Ascorbyl Tetraisopalmitate, tocopherol acetas, butylated hydroxytoluene, retinyl palmitate mix and blend after heating for dissolving, temperature control becomes oil phase combination liquid at 70-80 DEG C.
2) by after propylene glycol, AVC, allantoin, citric acid, EDETATE SODIUM, deionized water mix and blend heating for dissolving, temperature control becomes aqueous phase combination liquid at 80-90 DEG C.
3) oil phase is combined liquid to pour in aqueous phase combination liquid, cool after homogenizing; Wherein, rotating speed during homogenizing is 2500-3500RPM and the time is 4-6 minute, and after cooling, temperature is 42-48 DEG C;
4) in the semi-finished product that previous step is obtained, add Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract, DMDM Hydantoin, iodine propilolic alcohol butyl mephenesin Carbamate, essence, the coated retinol of liposomes, after homogenizing, obtain the semi-finished product of whitening and spot eliminating cream; Its homogenizing process is,
1. homogenizing rotating speed is 2500-3500RPM, stirs 0.5-1.5 minute;
2. speed of agitator is reduced to 800-1200RPM and evacuation from 0 to-0.1Mpa, Keep agitation is cooled to less than 35 degrees Celsius.
5) semi-finished product of whitening and spot eliminating cream are obtained whitening and spot eliminating cream finished product after filling nitrogen fill sealing.
Below in conjunction with Figure of description, the nitrogen conduit loading tail sealing machine that fills in the present invention is described further, but the present invention is not limited to following examples.
As shown in Figure 1, a kind of produce whitening and spot eliminating cream fill nitrogen conduit loading tail sealing machine, filling components wherein comprises material feeding bucket 1, interior material filling adaptor 2, fills nitrogen joint 3, exhaust joint 4, storage nitrogen equipment 6, electromagnetic valve 5, PLC 7; Folding sealing operation is then completed by folding sealing assembly (conventional equipment).
Wherein: material feeding bucket is the container of housing shape, its top be shaped with for feed openings, for taper bottom it; Interior material filling adaptor, fill in adapter 7 that nitrogen joint, exhaust joint be all arranged on below material feeding bucket and be arranged side by side together; Interior material filling adaptor is communicated with material feeding bottom of the barrel by material receiving tube; Fill nitrogen joint to be communicated with (store up nitrogen equipment and be generally nitrogen cylinder, internal pressure is at more than 0.4MP) with storage nitrogen equipment by flexible pipe 6-1; Exhaust joint is also communicated with air by trachea 4-1; The trachea of the material receiving tube of interior material filling adaptor, the flexible pipe filling nitrogen joint and exhaust joint is all interspersed to be arranged in adapter, and electromagnetic valve installed respectively by material receiving tube and flexible pipe; All electromagnetic valves are all connected with PLC (PLC is for controlling all electromagnetic valves); In addition, the diameter filling nitrogen joint is generally 6-10MM, and the diameter of exhaust joint is general 1-3MM.
Work process of the present invention is as follows:
1, all electromagnetic valves are all in closed condition, and the rotary-tray of filling machine puts into container to be filled;
2, the electromagnetic valve filled on nitrogen joint is opened, and the container being positioned at current station is charged noble gas, and the air in container is discharged from exhaust joint;
3, fill the closed electromagnetic valve on nitrogen joint, the electromagnetic valve on interior material filling adaptor is opened, and interior material filling adaptor pours into whitening and spot eliminating cream in container;
4, close the electromagnetic valve on interior material filling adaptor and rotary-tray startup, carry out the fill of next station.
Claims (3)
1. add a production technology for the whitening and spot eliminating cream of whitening and speckle dispelling compound material, comprise the following steps:
1) by ethylhexyl palmitate, Cyclomethicone, stereth-2, cetearyl alcohol, Parleam, stereth-21, the different pelargonate of cetearyl alcohol, olive oil, dicaprylyl carbonate, titanium dioxide, Ascorbyl Tetraisopalmitate, tocopherol acetas, butylated hydroxytoluene, lecithin, retinyl palmitate mix and blend heating for dissolving, temperature control becomes oil phase combination liquid at 70-80 DEG C;
2) by propylene glycol, AVC, allantoin, citric acid, EDETATE SODIUM, deionized water mix and blend heating for dissolving, temperature control becomes aqueous phase combination liquid at 80-90 DEG C;
3) oil phase is combined liquid to pour in aqueous phase combination liquid, after homogenizing, Keep agitation cools;
4) in the semi-finished product that previous step is obtained, Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract, DMDM Hydantoin, iodine propilolic alcohol butyl mephenesin Carbamate, essence, the coated retinol of liposomes is added, evacuation after homogenizing is also cooled to less than 35 DEG C, obtains the semi-finished product of whitening and spot eliminating cream;
5) semi-finished product of whitening and spot eliminating cream are obtained whitening and spot eliminating cream finished product after filling nitrogen fill sealing.
2. the production technology of the whitening and spot eliminating cream of interpolation whitening and speckle dispelling compound material according to claim 1, it is characterized in that described step 3) in homogenizing time rotating speed be 2500-3500RPM{Revolutions Per Minute (rev/min) and the time be 4-6 minute, cooling after temperature be 42-48 DEG C.
3. the production technology of the whitening and spot eliminating cream of interpolation whitening and speckle dispelling compound material according to claim 2, it is characterized in that described step 4) in homogenizing process be: first stir 0.5-1.5 minute when rotating speed is 2500-3500RPM, then rotating speed is reduced to 800-1200RPM and evacuation from 0 to-0.1Pa, Keep agitation is cooled to less than 35 degrees Celsius.
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| CN105947953B (en) * | 2016-06-30 | 2019-05-03 | 东莞轩朗实业有限公司 | The process units of quantum dot striation |
| CN106265338B (en) * | 2016-09-14 | 2020-02-14 | 广东丸美生物技术股份有限公司 | Skin care oil with whitening, spot-fading and skin-smoothing functions and preparation method thereof |
| CN108210362A (en) * | 2016-12-14 | 2018-06-29 | 天津强微特生物科技有限公司 | A kind of VACE Essences of freckle removing and whitening |
| CN106821794A (en) * | 2017-01-11 | 2017-06-13 | 杭州菲丝凯化妆品有限公司 | Eye bottoming cream and preparation method thereof |
| CN108888522A (en) * | 2018-07-24 | 2018-11-27 | 上海东晟源日化有限公司 | A kind of skin care liposomes inclusion enclave |
| CN109700696A (en) * | 2019-01-29 | 2019-05-03 | 江苏格创生物科技有限公司 | A kind of freckle removing and whitening anti-ageing cream and preparation method thereof |
| CN115364004A (en) * | 2021-10-19 | 2022-11-22 | 广州一一生物技术有限公司 | Vitamin composition for whitening, moisturizing and controlling oil and preparation method thereof |
| CN114709031B (en) * | 2022-04-25 | 2023-05-30 | 重庆科宝电缆股份有限公司 | Magnesia powder feeding hopper and copper pipe sheath magnesia insulated cable filling method |
| CN114709032B (en) * | 2022-04-25 | 2023-06-27 | 重庆科宝电缆股份有限公司 | Filling method for filling magnesia drainage tube and magnesia insulation fireproof cable |
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| DE10233740A1 (en) * | 2002-07-24 | 2004-02-05 | Basf Ag | Preparations containing retinoids |
| EP1575930B1 (en) * | 2002-12-18 | 2008-07-23 | Coreana Cosmetics Co., Ltd. | Novel retinol derivative and cosmetic composition comprising the same |
| CN100496451C (en) * | 2004-10-22 | 2009-06-10 | 卢藏田 | Composite whitening speckle-removing liquor |
| CN102008729A (en) * | 2005-01-07 | 2011-04-13 | 日本乐敦制药株式会社 | Composition for external use |
| CN101181198A (en) * | 2007-12-06 | 2008-05-21 | 曹月秀 | Nourishing type spot-eliminating and beautifying cream |
| CN101317815B (en) * | 2008-05-23 | 2010-09-15 | 海南京润珍珠生物技术股份有限公司 | Spot-removing cream containing pearl hydrolysate liposome |
| CN103479552B (en) * | 2011-08-25 | 2015-10-21 | 唯美度科技（北京）有限公司 | Crease-resistant easypro eye cream alive and preparation method |
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