CN103416825B - Granulating-dedicated coarse feed composite mildew inhibitor and preparation method thereof - Google Patents
Granulating-dedicated coarse feed composite mildew inhibitor and preparation method thereof Download PDFInfo
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- CN103416825B CN103416825B CN201210154286.XA CN201210154286A CN103416825B CN 103416825 B CN103416825 B CN 103416825B CN 201210154286 A CN201210154286 A CN 201210154286A CN 103416825 B CN103416825 B CN 103416825B
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Abstract
The invention discloses a granulating-dedicated coarse feed composite mildew inhibitor and a preparation method thereof, especially relates to a dedicated composite mildew inhibitor for making granulated coarse feed and a preparation method thereof, and aims to solve the problem of no a mildew inhibitor product, which is dedicated for coarse feed in the feed market at present. The formula of the composite mildew inhibitor comprises following components: calcium propionate, potassium sorbate, sodium benzoate, dimethyl fumarate, zeolite powder, aflatoxin degrading enzyme, and carriers. The preparation method comprises following steps: first, weighing 4.5 kg of calcium propionate, 5 kg of potassium sorbate, 4.5 kg of sodium benzoate, 6.0 kg of dimethyl fumarate, and 8.0 kg of aflatoxin degrading enzyme; secondly, pre-mixing the components in a small feed mixing machine for 10 minutes, then adding 27.0 kg of zeolite powder and 45.0 kg of corncob powder, putting the mixture into the small feed mixing machine again, and mixing for another 15 minutes so as to obtain the product. The granulating-dedicated coarse feed composite mildew inhibitor has the advantages of no toxicity, no accumulation in animal bodies, and no affection on nutrition value and palatability of coarse feed.
Description
Technical field:
The present invention relates to a kind of specific complex mould inhibitor of making particle roughage and preparation method thereof.
Background technology:
Mould is the key factor that affects feed nutritive value and feed safety, roughage is the feedstuff of ruminant use amount maximum, yet it is relatively simple that roughage processing is processed, mould is usually caused the significant damage to animal and animal's products to the pollution of roughage because prevention is not enough.The straw feed that ruminant is often widely applied is usually just subject to multiple sickle mycete and infects when not yet gathering in the crops, and has again the mould contaminations such as aspergillus fumigatus, aspergillus parasiticus, Aspergillus ochraceus, aspergillus flavus in stalk storage process.These moulds reduce the nutritive value of roughage, palatability variation, metabolite-mycotoxin that these moulds produce in growth metabolism process simultaneously-animal and the mankind are had to great harm, particularly aflatoxin extensively exists in roughage, often cause growth of animal to be obstructed, immunity reduces, premunition weakens, and histoorgan is impaired, reproductive capability declines, miscarriage, and mycotoxin is residual in livestock products and then threat human health also.
Mould inhibitor kind on feed market is a lot of at present, but due to applicable condition and effect limits, still there is no a mould inhibitor product using for roughage specially.
Summary of the invention:
Technical problem to be solved by this invention is to provide a kind ofly specially to be used with roughage for granulating, mould fungus inhibition effect is good, can extend roughage storage period, non-toxic, nonirritant, do not accumulate in animal body, non-volatile when storing, do not affect the special-purpose roughage composite mildew inhibitor of the nutritive value of roughage and the granulation of palatability and preparation method.
Above-mentioned purpose is achieved in that the formula of described composite mildew inhibitor comprises: calcium propionate, potassium sorbate, Sodium Benzoate, dimethyl fumarate, zeolite powder, aflatoxin digestive enzyme, carrier.
In described formula, each composition accounts for the percentage of gross weight and is:: calcium propionate 4.5%, potassium sorbate 5.0%, Sodium Benzoate 4.5%, dimethyl fumarate 6.0%, zeolite powder 27.0%, aflatoxin digestive enzyme 8.0%, carrier 45.0%.
Described carrier is maize cob meal.
Preparation method:
According to the mass percent of this formula, first take calcium propionate 4.5kg, potassium sorbate 5kg, Sodium Benzoate 4.5kg, dimethyl fumarate 6.0kg, aflatoxin digestive enzyme 8.0kg, in small-sized feed mixing machine, carry out premix 10 minutes, and then add zeolite powder 27.0kg, maize cob meal 45.0kg, again drop in mixer and mix again 15 minutes.
Mixed composite mildew inhibitor divided and installed in the polybag that internal layer is lined with diaphragm seal, and every packed 25kg, is placed in shady and cool dry environment and stores.The effective content of this composite mildew inhibitor is 55%, and in the roughage of granulating, suitable adding proportion is 1.5% ~ 2.0%.
Advantage of the present invention is: this composite mildew inhibitor consists of three levels.The first level is chemical mildew-resistant, applies several chemical anti mildew agents and carries out scientific matching, makes the applicable PH scope of its mildew-resistant reach 2.5 ~ 8, and antifungi spectrum is wide.In its active ingredient, first calcium propionate discharges propionic acid molecule, and the latter can form the high environment that oozes and make mould dehydration outside fungal cell, and loses fertility, also can enter fungal cell, suppresses the activity of desmoenzyme, thus the breeding of mould fungus inhibition.Potassium sorbate first resolves into sorbic acid, and the enzyme system that the latter destroys mould reaches antibacterial.Sodium Benzoate is to pierce into fungal cell by benzoic acid bioactive molecule, suppresses respiratory enzyme and hinders tricarboxylic acid cycle process, and the while is the saturating property of block cell film also, and reaches the effect of mould fungus inhibition breeding.Dimethyl fumarate can penetrate fungal cell film, suppress the activity of key enzyme in cell division, inhibition glycometabolism, thereby the respiration of mould fungus inhibition reaches anti-mold effect.
The second level is to use zeolite powder (main component is aluminosilicate) as adsorbent, make pellet after entering animal alimentary canal, the frame shape structure of alumino-silicate can be brought into play adsorption function, hole and the cation in passage in its molecule also have ion exchanging function, can optionally adsorb and in conjunction with upper mould and mycotoxin, these are not absorbed by animal the harmful material of animal, form special group gastrointestinal motor discharge backward.
Tri-layer is application aspergillus flavus toxin digestive enzyme (ADTZ), and it is a kind of protease that derives from edible mushroom, can play a role by special specific chemical constitution-bifuran for aflatoxin, makes its open loop become innocuous substance.Aspergillus flavus toxin digestive enzyme specificity is high, only for mycotoxin, works and can not destroy the nutrition of feed.In animal alimentary canal, temperature, humidity and PH be suitable aspergillus flavus toxin digestive enzyme performance degradation all, before two unsolved mycotoxins of level in this step, thoroughly eliminated, reach the object that guarantees to greatest extent animal feed safety.
When roughage is granulated, the pyroprocess of 75 ℃ that can experience 20 ~ 30 seconds during through mould when raw material.And there is not the change of physicochemical property in above several mould inhibitor raw material Heat stability is goods at this temperature.Several advantages of nontoxic raw materials in addition, nonirritant, does not accumulate in animal body, non-volatile when storing, and does not affect nutritive value and the palatability of roughage.
The specific embodiment:
The formula of described composite mildew inhibitor comprises: calcium propionate, potassium sorbate, Sodium Benzoate, dimethyl fumarate, zeolite powder, aflatoxin digestive enzyme, carrier.
In described formula, each composition accounts for the percentage of gross weight and is: calcium propionate 4.5%, potassium sorbate 5.0%, Sodium Benzoate 4.5%, dimethyl fumarate 6.0%, zeolite powder 27.0%, aflatoxin digestive enzyme 8.0%, carrier 45.0%.
Described carrier is maize cob meal.
Preparation method:
According to the mass percent of this formula, first take calcium propionate 4.5kg, potassium sorbate 5kg, Sodium Benzoate 4.5kg, dimethyl fumarate 6.0kg, aflatoxin digestive enzyme 8.0kg, in small-sized feed mixing machine, carry out premix 10 minutes, and then add zeolite powder 27.0kg, maize cob meal 45.0kg, again drop in mixer and mix again 15 minutes.
Mixed composite mildew inhibitor divided and installed in the polybag that internal layer is lined with diaphragm seal, and every packed 25kg, is placed in shady and cool dry environment and stores.The effective content of this composite mildew inhibitor is 55%, and in the roughage of granulating, suitable adding proportion is 1.5% ~ 2.0%.
Effect:
1. by mycotic culture and drug sensitive test, find, the different proportion screening by calcium propionate, potassium sorbate, Sodium Benzoate, dimethyl fumarate shows, this composite mildewproof agent prescription mould fungus inhibition effect is the most effective.Compare with similar feed composite mildew inhibitor on market, under identical mould bacteria concentration and condition of culture, the bacteriostatic diameter of this composite mildew inhibitor reaches 29.45mm, and than the large 12.51mm of similar mould inhibitor bacteriostatic diameter, difference is (P < 0.01) extremely significantly.
2. Liaoning Cashmere Goat feeding experiment shows, in particle daily ration, add under the prerequisite of same amount aflatoxin, extra this composite mildew inhibitor 1.5% that adds in test group daily ration, control group adds conventional propionic acid composite mildew inhibitor (adding by products instruction consumption), after 30 days, test group down producing goat feed intake is than the high 0.21kg of control group, significant difference (P < 0.05); Daily gain improves 0.02kg, significant difference (P < 0.05); Liver Superoxide Dismutase Activity specific activity control group rising 7.74(P < 0.05), glutathione peroxidase is than control group rising 14.74(P < 0.01), mda content reduces 11.08%(P < 0.05).This shows that the aflatoxin digestive enzyme in this composite mildew inhibitor is remarkable to the aflatoxin effect of decomposing in animal body, has eliminated the toxicity of aflatoxin to animal, and has improved animal's liver function, has improved production performance.
3. will add the straw pellet of 1.5% composite mildew inhibitor and add the pellet feeds from stalks of conventional propionic acid type composite mildew inhibitor (pressing products instruction consumption adds), under the hot and humid condition that to be placed on temperature and to be 27.0 ℃ ~ 29.0 ℃, humidity be 85% ~ 92%, store, at the 19th day control group storing, start to have mould to produce, wherein the mouldy rate of particle is 21.54%, and now the mouldy rate of test group is 0.Until test group particle just has 12.25% feed granules mouldy while being stored into the 34th day.This shows under hot and humid environment, to extend 15 days feed storage lifves, significant difference (P < 0.05).
To add the straw pellet of 1.5% composite mildew inhibitor and add the pellet feeds from stalks of conventional propionic acid type composite mildew inhibitor (pressing products instruction consumption adds), under the condition that to be placed on 27.0 ℃ ~ 29.5 ℃, humidity be 80% ~ 85%, test group pellet can store 51 days, than control group, can extend 19 days (P < 0.05).
To add the straw pellet of 1.5% composite mildew inhibitor and add the pellet feeds from stalks of conventional propionic acid type composite mildew inhibitor (pressing products instruction consumption adds), under the condition that to be placed on temperature and to be 20 ℃, humidity be 70% ~ 75%, can store 88 days, than control group, extend 28 days (P < 0.05).
Claims (2)
1. the special-purpose roughage composite mildew inhibitor of granulation, is characterized in that: formula is comprised of calcium propionate, potassium sorbate, Sodium Benzoate, dimethyl fumarate, zeolite powder, aflatoxin digestive enzyme, carrier; In described formula, each composition accounts for the percentage of gross weight and is: calcium propionate 4.5%, potassium sorbate 5.0%, Sodium Benzoate 4.5%, dimethyl fumarate 6.0%, zeolite powder 27.0%, aflatoxin digestive enzyme 8.0%, carrier 45.0%.
2. the preparation method of special-purpose roughage composite mildew inhibitor that granulates, it is characterized in that: first take calcium propionate 4.5kg, potassium sorbate 5kg, Sodium Benzoate 4.5kg, dimethyl fumarate 6.0kg, aflatoxin digestive enzyme 8.0kg, in small-sized feed mixing machine, carry out premix 10 minutes, and then add zeolite powder 27.0kg, carrier 45.0kg, again drop in mixer and mix again 15 minutes.
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| CN106721074A (en) * | 2016-12-20 | 2017-05-31 | 大连赛姆生物工程技术有限公司 | The method for being combined production specific yolk antibody preparation with the specific egg pulp that shells using the zeolite powder of ultramicro grinding |
| CN107183484A (en) * | 2017-06-01 | 2017-09-22 | 烟台东和饲料科技有限公司 | It is a kind of for the composition of feedstuff mildew, preparation method and its application method |
| CN108850783A (en) * | 2018-06-13 | 2018-11-23 | 西安默瑞柯生物科技有限公司 | One boar food mycotoxin adsorption degradation agent and preparation method thereof |
| CN110050886A (en) * | 2019-05-15 | 2019-07-26 | 北京波尔莱特饲料有限公司 | A kind of dry and wet mixing complete feed of long shelf-life and preparation method thereof |
| CN110499254B (en) * | 2019-07-22 | 2022-05-06 | 吉林大学 | Saline-alkali-resistant aspergillus ochraceus strain W1, and microbial inoculum and application thereof |
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