CN103416417A - Sterilization composition containing xemium - Google Patents
Sterilization composition containing xemium Download PDFInfo
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- CN103416417A CN103416417A CN2012101663991A CN201210166399A CN103416417A CN 103416417 A CN103416417 A CN 103416417A CN 2012101663991 A CN2012101663991 A CN 2012101663991A CN 201210166399 A CN201210166399 A CN 201210166399A CN 103416417 A CN103416417 A CN 103416417A
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- azoles bacterium
- bacterium acid
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Abstract
The invention discloses a sterilization composition containing xemium. The sterilization composition comprises active component A and active component B at a weight ratio of 1:80-60:1. The active component A is xemium; and the active component B is one component optionally selected from cyazofamid, dimethomorph, propamocarb or a salt of propamocarb, cymoxanil, metalaxyl or a salt of metalaxyl, and iprovalicarb. The sterilization composition possesses relatively high activity on a plurality of diseases of a plurality of kinds of crops, and obvious synergistic effect; and the bacteriocidal spectrum is enlarged. In addition, drugs dose is small, the sterilization composition is capable of resisting rain wash, and the synergistic effect is obvious.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on crop pest of fluorine-containing azoles bacterium acid amides.
Technical background
Fluorine azoles bacterium acid amides (Fluxapyroxad) chemical name: 3-(difluoro)-1-methyl-N-(3', 4', 5'-trifluoro [1,1'-biphenyl]-2-yl)-1-H-pyrazoles-4-acid amides, fluorine azoles bacterium acid amides belongs to pyrazole amide series bactericidal agent, succinate dehydrogenase inhibitors.Superior lasting effect and lasting transmission characteristic are integrated in one.
The chloro-2-cyano group of cyazofamid (Cyazofamid) chemical name: 4--5-p-methylphenyl-imidazoles-1-N, N-dimethyl leech acid amides, molecular formula: C
13H
13ClN
4O
2S.It is the sulphaguanidine azoles fungicide, super protective fungicide.Mechanism of action is the supply that the electronics transmission of mitochondrial cytochrome b c1 complex in blocking-up Oomycete germ body carrys out interfering energy, and its binding site is Mei De Q1 center, with other bactericide without cross tolerance.It may be because the sensitivity difference of target enzyme to medicament causes that its height to pathogen is selected activity.
Dimethomorph (Dimethomorph) chemical name: (E, Z)-4-[3-(4-chlorphenyl) 3-(3,4-Dimethoxyphenyl) acryloyl] morpholine, molecular formula: C
21H
22ClNO
4.Dimethomorph is single-minded ovicidal Gammaproteobacteria fungi bactericide, its effect characteristics are to destroy the formation of cell envelope, stages to oomycetes history of life has effect, and particularly responsive at the formation stages of sporangiophore and egg spore, under extremely low concentration, (<0.25 μ g/ml) is suppressed.With the phenylamide medicament without cross resistance.
Propamocarb (Propamocarb) chemical name: 3-(dimethylamino) propyl carbamic acid propyl ester, molecular formula: C
9H
21N
2O
2Cl.The salt of Propamocarb can be propamocarb (Propamocarb hydrochloride), chemical name: propyl group-3-(dimethylamino) propyl carbamic acid hydrochloride.Propamocarb or its salt all have local systemic action, also can be used as impregnation process and seed protectant.
Frost urea cyanogen (Cymoxanil) chemical name: 2-cyano group-N-[(ethylamino-) carbonyl]-2-(methoxyl group imido grpup) acetamide, molecular formula: C
7H
10N
4O
3, there is contact and local systemic action, can suppress spore germination, effective to downy mildew of garpe, epidemic disease etc., mixed with protective fungicide to extend the lasting period.
Metalaxyl (Metalaxyl) chemical name: D, L-N-(2,6-3,5-dimethylphenyl)-N-(2'-methoxyl group acetyl) methyl lactamine, molecular formula: C
15H
21NO
4.The salt of metalaxyl can be Metalaxyl-M (Metalaxyl-M), chemical name: N-(2,6-xylyl)-N-(methoxyl group acetyl group)-D-alanine methyl esters.Metalaxyl or its salt are for having protection and therapeutic action; have systemic action concurrently; can be absorbed by the root of plant, stem, leaf; and transfer to each organ of plant with moisture content in plant corpus; can make cauline leaf processes; seed treatment and soil treatment are effective to downy mildew, phytophthora, the caused disease of pythium spp.
Iprovalicarb (Iprovalicarb) chemical name: [2-methyl isophthalic acid-[1-(4-aminomethyl phenyl)-ethylamino formoxyl]-propyl group]-carbamyl isopropyl ester, molecular formula: C
18H
28N
2O
3.Iprovalicarb is the amino-acid ester analog derivative, has unique brand-new biomimetic features and makes its mechanism of action be different from the bactericide that other prevent and treat Oomycete.Its mechanism of action is act on fungal cell wall and protein synthetic, can suppress infecting and sprouting of spore, can suppress mycelial growth, causes its distortion, death simultaneously.There is good treatment and eradicant action for Peronosporaceae and the fungus-caused disease of Phytophthora.
In the real process of agricultural production, preventing and treating the problem that disease the most easily produces is the generation of disease drug resistance.The different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor's research, discovery is mutually composite by fluorine azoles bacterium acid amides and cyazofamid, dimethomorph, Propamocarb or its salt, white urea cyanogen, metalaxyl or its salt, iprovalicarb, good synergistic effect is arranged within the specific limits, and relevant composite about fluorine azoles bacterium acid amides and cyazofamid, dimethomorph, Propamocarb or its salt, white urea cyanogen, metalaxyl or its salt, iprovalicarb, there is not yet relevant report at present at home and abroad.
Summary of the invention
The objective of the invention is to propose a kind of bactericidal composition with synergistic function, use cost is low, preventive effect is good fluorine-containing azoles bacterium acid amides.
The present invention is achieved through the following technical solutions:
A kind of bactericidal composition of fluorine-containing azoles bacterium acid amides, it is characterized in that containing active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is selected from fluorine azoles bacterium acid amides, and active component B is selected from a kind of in cyazofamid, dimethomorph, Propamocarb or its salt, white urea cyanogen, metalaxyl or its salt, iprovalicarb.The preferred weight ratio of active components A and active component B is 1 ︰ 50 ~ 40 ︰ 1; More preferably the weight ratio of fluorine azoles bacterium acid amides and cyazofamid is 1 ︰ 20 ~ 20 ︰ 1; The weight ratio of fluorine azoles bacterium acid amides and dimethomorph is 1 ︰ 25 ~ 10 ︰ 1; The weight ratio of fluorine azoles bacterium acid amides and Propamocarb or its salt is 1 ︰ 40 ~ 5 ︰ 1; The weight ratio of fluorine azoles bacterium acid amides and white urea cyanogen is 1 ︰ 30 ~ 15 ︰ 1; The weight ratio of fluorine azoles bacterium acid amides and metalaxyl or its salt is 1 ︰ 30 ~ 5 ︰ 1; The weight ratio of fluorine azoles bacterium acid amides and iprovalicarb is 1 ︰ 30 ~ 20 ︰ 1.
The disease of the bactericidal composition of described fluorine-containing azoles bacterium acid amides for preventing and treating crop, described crop comprises fruit tree, vegetables, cereal crops, ornamental plants.
Described disease comprises moire disease, leaf spot, net blotch, rust, late blight, downy mildew, peronospora tabacina, epidemic disease, balck shank, damping off, white rot, anthracnose, white blister, foot rot.
Amount of application when in the present composition, the content of active component depends on independent use, also depend on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target disease.Usually in composition, the weight percentage of active component is gross weight 1%～90%, is preferably 5%～80%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1%～60% active substance by weight, is preferably 5%～50%; Solid pharmaceutical preparation contains 5%～80% active substance by weight, is preferably 10%～80%.
At least contain a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water while being beneficial to use.Surface-active contents is 2%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, thickener or defoamer.According to different dosage form, in preparation, can also contain stabilizing agent known in those skilled in the art, antifreeze etc.
Bactericidal composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by processing method known in those skilled in the art preparation, is about to active component and after liquid flux or solid carrier mix, then adds surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer etc.
Bactericidal composition of the present invention, can be processed into acceptable formulation on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-suspending agent, also can be made into aqua, soluble liquid, soluble powder.
When making wetting powder, composition comprises following component and content: active components A 1% ~ 60%, active component B1% ~ 80%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, filler surplus.
When making water dispersible granules, composition comprises following component and content: active components A 1% ~ 60%, active component B1% ~ 80%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Comprise following component and content when composition is made suspending agent: active components A 1% ~ 50%, active component B1% ~ 50%, dispersant 1% ~ 10%, wetting agent 1% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Comprise following component and content when composition is made suspension emulsion: active components A 1% ~ 50%, active component B1% ~ 50%, emulsifier 1% ~ 10%, dispersant 1% ~ 10%, solvent 0 ~ 20%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Comprise following component and content when composition is made microemulsion: active components A 1% ~ 50%, active component B1% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Comprise following component and content when composition is made aqueous emulsion: active components A 1% ~ 50%, active component B1% ~ 50%, solvent 1% ~ 20%, emulsifier 1% ~ 12%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
The invention has the advantages that:
(1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single dose; (2) the agricultural chemicals dosage reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) enlarged fungicidal spectrum, multiple diseases has been had to greater activity as moire disease, leaf spot, net blotch, rust, late blight, downy mildew, peronospora tabacina, epidemic disease, balck shank, damping off, white rot, anthracnose, white blister, foot rot.
Embodiment
Below in conjunction with embodiment, to further instruction of the present invention, the percentage in embodiment all is weight percentage, but the present invention is not limited thereto.
Application Example one
Example 1 ~ 20 wetting powder
Fluorine azoles bacterium acid amides, active component B, dispersant, wetting agent, filler are mixed, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, can be made into wetting powder product of the present invention.Specifically in Table 1,2.
Table 1 example 1 ~ 10 each component and content
Table 2 example 11 ~ 20 each component and content
Example 21 ~ 40 water dispersible granules
Fluorine azoles bacterium acid amides, active component B, dispersant, wetting agent, disintegrant, binding agent (can add and can not add), filler are obtained to the particle diameter of needs together through air-flow crushing, obtain the materials of granulating.By item quantitatively send in the fluidized bed granulation dryer through granulation and drying after, make water dispersible granules product of the present invention.Specifically in Table 3,4.
Table 3 example 21 ~ 30 each component and content
Table 4 example 31 ~ 40 each component and content
Example 41 ~ 58 suspending agents
Dispersant, wetting agent, thickener (can add and can not add), defoamer, antifreeze (can add and can not add) are mixed through high speed shear, add fluorine azoles bacterium acid amides, active component B, supply surplus by deionized water, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make suspending agent product of the present invention.Specifically in Table 5,6.
Table 5 example 41 ~ 50 each component and content
Table 6 example 51 ~ 58 each component and content
Table 1 to cyazofamid, dimethomorph, Propamocarb or its salt, white urea cyanogen, metalaxyl, iprovalicarb in table 6 exchanged, can make novel formulation.
Example 59 ~ 71 suspension emulsions
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), deionized water are mixed through high speed shear, add fluorine azoles bacterium acid amides, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make fluorine azoles bacterium acid amides suspending agent, then by active component B, solvent (can add and can not add), emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make suspension emulsion product of the present invention.Specifically in Table 7,8.
Table 7 example 59 ~ 67 each component and content
Table 8 example 65 ~ 71 each component and content
Example 72 ~ 81 aqueous emulsions
Fluorine azoles bacterium acid amides, active component B, solvent, emulsifier are added together, make to be dissolved into even oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, become the homogeneous water.Under high-speed stirred, water is added to oil phase, make aqueous emulsion product of the present invention.Specifically in Table 9.
Table 9 example 72 ~ 81 each component and content
Table 7 to cyazofamid, dimethomorph, Propamocarb or its salt, white urea cyanogen, metalaxyl or its salt, iprovalicarb in table 9 exchanged, can make novel formulation.
Example 82 ~ 84 microemulsions
Fluorine azoles bacterium acid amides, active component B are dissolved in the homogenizer that solvent is housed, emulsifier, antifreeze (can add and can not add), defoamer are joined in the homogenizer that above-mentioned solution is housed, give strong the mixing and homogenize after supplying surplus by deionized water, finally obtain the as clear as crystal microemulsion product of the present invention of outward appearance.Specifically in Table 10.
Table 10 example 82 ~ 84 each component and content
Example 85,86 microcapsule suspending agents
By fluorine azoles bacterium acid amides, active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, under shearing condition, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent, dispersant, defoamer, supply surplus by deionized water, bi-material reacts at oil-water interfaces, forms the macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in Table 11.
Table 11 example 85,86 each component and content
Example 87,88 microcapsule suspensions-suspending agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent under shearing condition, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add fluorine azoles bacterium acid amides, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make suspending agent, then suspending agent is joined in the aqueous phase solution of micro-capsule suspension, deionized water is supplied surplus, makes the finely disseminated microcapsule suspension of the present composition-suspending agent product.Specifically in Table 12.
Table 12 example 87,88 each component and content
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR<0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect, on this basis, then carry out field trial.
Test method: after the effective inhibition concentration scope of each medicament is determined in prerun, medicament is established respectively 5 dosage by active constituent content and is processed, and establishes the clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament to the crop germ.Measure colony diameter by the right-angled intersection method after 72h, calculate and respectively process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into to probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, with method of least squares, tries to achieve virulence regression equation (y=a+bx), and calculates thus the EC of every kind of medicament
50Value.Calculate the different proportioning synergy ratio (SR) of two medicaments according to the Wadley method, SR<0.5 is antagonism simultaneously, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and active component B shared ratio in combination;
A is fluorine azoles bacterium acid amides; B selects a kind of in cyazofamid, dimethomorph, Propamocarb or its salt, white urea cyanogen, metalaxyl or its salt, iprovalicarb.
Application Example two:
For trying disease: tomato late blight; Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd.; Experimental scheme: effective inhibition concentration scope of determining fluorine azoles bacterium acid amides and the former medicine of cyazofamid and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to tomato late blight of table 13 fluorine azoles bacterium acid amides and cyazofamid
As shown in Table 13, the proportioning of fluorine azoles bacterium acid amides and the composite control tomato late blight of cyazofamid is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of fluorine azoles bacterium acid amides and cyazofamid during at 1 ︰ 20 ~ 20 ︰ 1, synergistic effect is more outstanding, and synergy ratio all is greater than 2.20.The optimum ratio of finding fluorine azoles bacterium acid amides and cyazofamid through test is 20:1,15:1,10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20, especially synergy ratio maximum when fluorine azoles bacterium acid amides and cyazofamid weight ratio are 1:1, synergistic effect is the most obvious.
Application Example three:
For trying disease: cucumber downy mildew; Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd.; Experimental scheme: effective inhibition concentration scope of determining fluorine azoles bacterium acid amides and the former medicine of dimethomorph and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to cucumber downy mildew of table 14 fluorine azoles bacterium acid amides and dimethomorph
As shown in Table 14, the proportioning of fluorine azoles bacterium acid amides and the composite control cucumber downy mildew of dimethomorph is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of fluorine azoles bacterium acid amides and dimethomorph during at 1 ︰ 25 ~ 10 ︰ 1, synergistic effect is more outstanding, and synergy ratio all is greater than 2.30.The optimum ratio of finding fluorine azoles bacterium acid amides and dimethomorph through test is 10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,1:1,1:2,2:5,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:25, especially synergy ratio maximum when fluorine azoles bacterium acid amides and dimethomorph weight ratio are 2:5, synergistic effect is the most obvious.
Application Example four:
For trying disease: Cucumber Blight; Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd.; Experimental scheme: effective inhibition concentration scope of determining fluorine azoles bacterium acid amides and Propamocarb or the former medicine of its salt and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to Cucumber Blight of table 15 fluorine azoles bacterium acid amides and Propamocarb or its salt
As shown in Table 15, the proportioning of fluorine azoles bacterium acid amides and Propamocarb or the composite cucumber blight disease of its salt is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of fluorine azoles bacterium acid amides and Propamocarb or its salt during at 1 ︰ 40 ~ 5 ︰ 1, synergistic effect is more outstanding, and synergy ratio all is greater than 2.30.The optimum ratio of finding fluorine azoles bacterium acid amides and Propamocarb or its salt through test is 5:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:11,1:12,1:13,1:14,1:15,1:20,1:25,1:30,1:35,1:40, especially synergy ratio maximum when fluorine azoles bacterium acid amides and Propamocarb or its salt weight ratio are 1:8, synergistic effect is the most obvious.
Application Example five:
For trying disease: downy mildew of crucifers; Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd.; Experimental scheme: effective inhibition concentration scope of determining fluorine azoles bacterium acid amides and the former medicine of white urea cyanogen and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to downy mildew of crucifers of table 16 fluorine azoles bacterium acid amides and white urea cyanogen
As shown in Table 16, the composite proportioning of downy mildew of crucifers of preventing and treating of fluorine azoles bacterium acid amides and white urea cyanogen is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of fluorine azoles bacterium acid amides and white urea cyanogen during at 1 ︰ 30 ~ 15 ︰ 1, synergistic effect is more outstanding, and synergy ratio all is greater than 2.30.The optimum ratio of finding fluorine azoles bacterium acid amides and white urea cyanogen through test is 15:1,10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:25,1:30, especially synergy ratio maximum when fluorine azoles bacterium acid amides and white urea cyanogen weight ratio are 1:2, synergistic effect is the most obvious.
Application Example six:
For trying disease: downy mildew of garpe; Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd.; Experimental scheme: effective inhibition concentration scope of determining fluorine azoles bacterium acid amides and metalaxyl or the former medicine of its salt and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to downy mildew of garpe of table 17 fluorine azoles bacterium acid amides and metalaxyl or its salt
As shown in Table 17, the composite proportioning of downy mildew of garpe of preventing and treating of fluorine azoles bacterium acid amides and metalaxyl or its salt is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of fluorine azoles bacterium acid amides and metalaxyl or its salt during at 1 ︰ 30 ~ 5 ︰ 1, synergistic effect is more outstanding, and synergy ratio all is greater than 2.20.Especially synergy ratio maximum when fluorine azoles bacterium acid amides and metalaxyl or its salt weight ratio are 1:6, synergistic effect is the most obvious.
Application Example seven:
For trying disease: capsicum epidemic disease; Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd.; Experimental scheme: effective inhibition concentration scope of determining fluorine azoles bacterium acid amides and the former medicine of iprovalicarb and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to capsicum epidemic disease of table 18 fluorine azoles bacterium acid amides and iprovalicarb
As shown in Table 18, the proportioning of fluorine azoles bacterium acid amides and the composite control capsicum epidemic disease of iprovalicarb is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of fluorine azoles bacterium acid amides and iprovalicarb during at 1 ︰ 30 ~ 20 ︰ 1, synergistic effect is more outstanding, and synergy ratio all is greater than 2.20.Especially synergy ratio maximum when fluorine azoles bacterium acid amides and iprovalicarb weight ratio are 2:3, synergistic effect is the most obvious.
Through test, find: the control to moire disease, leaf spot, net blotch, rust, late blight, downy mildew, peronospora tabacina, epidemic disease, balck shank, damping off, white rot, anthracnose, white blister, foot rot after fluorine azoles bacterium acid amides and active component B are composite has obvious synergistic effect, and synergy ratio is all more than 1.50.
Test of pesticide effectiveness part
Test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd..Contrast medicament: 10% fluorine azoles bacterium acid amides suspending agent (autogamy), 100g/L cyazofamid suspending agent (commercial), 50% dimethomorph wetting powder (commercial), 35% Propamocarb aqua (commercial), 25% white urea cyanogen wetting powder (autogamy), 25% metalaxyl wetting powder (commercial), 20% iprovalicarb wetting powder (autogamy).
Application Example octafluoro azoles bacterium acid amides and active component B and the composite control tomato late blight test of pesticide effectiveness thereof
This test arrangement, at the Xian District, Shanxi Province suburban area, is investigated the tomato late blight state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 19 fluorine azoles bacterium acid amides and active component B and the composite control tomato late blight test of pesticide effectiveness thereof
As can be seen from Table 19, after fluorine azoles bacterium acid amides and active component B are composite, can effectively prevent and treat tomato late blight, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example nine fluorine azoles bacterium acid amides and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This test arrangement, in the Jingyang County, Shaanxi Province, is investigated the cucumber downy mildew state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 20 fluorine azoles bacterium acid amides and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
As can be seen from Table 20, after fluorine azoles bacterium acid amides and active component B are composite, can effectively prevent and treat cucumber downy mildew, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten fluorine azoles bacterium acid amides and active component B and the composite downy mildew of garpe test of pesticide effectiveness of preventing and treating thereof
This test arrangement, in Weinan City suburb, Shaanxi Province, is investigated the downy mildew of garpe state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 3 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 21 fluorine azoles bacterium acid amides and active component B and the composite downy mildew of garpe test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 21, after fluorine azoles bacterium acid amides and active component B are composite, can effectively prevent and treat downy mildew of garpe, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example 11 fluorine azoles bacterium acid amides and active component B and the composite control watermelon epidemic disease test of pesticide effectiveness thereof
This test arrangement, in Weinan City Dali County, Shaanxi Province, is investigated the watermelon epidemic disease state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 22 fluorine azoles bacterium acid amides and active component B and the composite control watermelon epidemic disease test of pesticide effectiveness thereof
As can be seen from Table 22, after fluorine azoles bacterium acid amides and active component B are composite, can effectively prevent and treat the watermelon epidemic disease, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten difluoro azoles bacterium acid amides and active component B and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
This test arrangement, at Shaanxi Province's Weinan City, is investigated the wheat rust state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 23 fluorine azoles bacterium acid amides and active component B and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 23, after fluorine azoles bacterium acid amides and active component B are composite, can effectively prevent and treat wheat rust, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten trifluoro azoles bacterium acid amides and active component B and the composite downy mildew of crucifers test of pesticide effectiveness of preventing and treating thereof
This test arrangement, at the Xian District, Shanxi Province suburban area, is investigated the downy mildew of crucifers state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 24 fluorine azoles bacterium acid amides and active component B and the composite downy mildew of crucifers test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 24, after fluorine azoles bacterium acid amides and active component B are composite, can effectively prevent and treat downy mildew of crucifers, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten tetrafluoro azoles bacterium acid amides and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
This test arrangement, in the Huilai county, Guangdong Province, is investigated the peronophythora litchi state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 25 fluorine azoles bacterium acid amides and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
As can be seen from Table 25, after fluorine azoles bacterium acid amides and active component B are composite, can effectively prevent and treat peronophythora litchi, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example 15 fluorine azoles bacterium acid amides and active component B and the composite control cucumber damping off test of pesticide effectiveness thereof
This test arrangement, in the Jingyang County, Shaanxi Province, is investigated the cucumber damping off state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 26 fluorine azoles bacterium acid amides and active component B and the composite control cucumber damping off test of pesticide effectiveness thereof
As can be seen from Table 26, after fluorine azoles bacterium acid amides and active component B are composite, can effectively prevent and treat the cucumber damping off, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten hexafluoro azoles bacterium acid amides and active component B and the composite control capsicum epidemic disease test of pesticide effectiveness thereof
This test arrangement, in Qishan County, Baoji, Shaanxi province city, is investigated the capsicum epidemic disease state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 27 fluorine azoles bacterium acid amides and active component B and the composite control capsicum epidemic disease test of pesticide effectiveness thereof
As can be seen from Table 27, after fluorine azoles bacterium acid amides and active component B are composite, can effectively prevent and treat capsicum epidemic disease, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
After through different local throughout the country tests, draw, fluorine azoles bacterium acid amides and cyazofamid, dimethomorph, Propamocarb or its salt, white urea cyanogen, metalaxyl or its salt, the composite rear preventive effect to Common Diseases such as the moire disease on various crop, leaf spot, net blotch, rust, late blight, downy mildew, peronospora tabacina, epidemic disease, balck shank, damping off, white rot, anthracnose, white blister, foot rots of iprovalicarb are all more than 95%, be better than the single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the bactericidal composition of a fluorine-containing azoles bacterium acid amides, it is characterized in that containing active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is selected from fluorine azoles bacterium acid amides, and active component B is selected from a kind of in cyazofamid, dimethomorph, Propamocarb or its salt, white urea cyanogen, metalaxyl or its salt, iprovalicarb.
2. the bactericidal composition of fluorine-containing azoles bacterium acid amides according to claim 1, it is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 50 ~ 40 ︰ 1.
3. the bactericidal composition of fluorine-containing azoles bacterium acid amides according to claim 2 is characterized in that:
The weight ratio of fluorine azoles bacterium acid amides and cyazofamid is 1 ︰ 20 ~ 20 ︰ 1;
The weight ratio of fluorine azoles bacterium acid amides and dimethomorph is 1 ︰ 25 ~ 10 ︰ 1;
The weight ratio of fluorine azoles bacterium acid amides and Propamocarb or its salt is 1 ︰ 40 ~ 5 ︰ 1;
The weight ratio of fluorine azoles bacterium acid amides and white urea cyanogen is 1 ︰ 30 ~ 15 ︰ 1;
The weight ratio of fluorine azoles bacterium acid amides and metalaxyl or its salt is 1 ︰ 30 ~ 5 ︰ 1;
The weight ratio of fluorine azoles bacterium acid amides and iprovalicarb is 1 ︰ 30 ~ 20 ︰ 1.
4. according to the bactericidal composition of the described fluorine-containing azoles bacterium acid amides of any one in claim 1-3, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
5. the bactericidal composition of fluorine-containing azoles bacterium acid amides according to claim 4, for preventing and treating the application of crop pest.
6. application according to claim 5 is characterized in that: described disease comprises moire disease, leaf spot, net blotch, rust, late blight, downy mildew, peronospora tabacina, epidemic disease, balck shank, damping off, white rot, anthracnose, white blister, foot rot.
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