CN105145584A - Sterilization composition containing penthiopyrad - Google Patents
Sterilization composition containing penthiopyrad Download PDFInfo
- Publication number
- CN105145584A CN105145584A CN201510556103.0A CN201510556103A CN105145584A CN 105145584 A CN105145584 A CN 105145584A CN 201510556103 A CN201510556103 A CN 201510556103A CN 105145584 A CN105145584 A CN 105145584A
- Authority
- CN
- China
- Prior art keywords
- pyrrole
- pyrrole metsulfovax
- salt
- active component
- metsulfovax
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a sterilization composition containing penthiopyrad. The sterilization composition contains an active component A and an active component B, wherein the active component A is selected from penthiopyrad; the active component B is selected from any one of the following compounds: cymoxanil, dimethomorph, propamocarb or a salt thereof, iprovalicarb, captan, chlorothalonil, metalaxyl or a salt thereof; the weight ratio of the component A to the component B ranges from (1:80) to (60:1). The composition has a synergistic effect on a plurality of types of diseases which endanger agricultural production; the dosage of pesticides is reduced; the residual amount of the pesticides on crops is reduced and the environmental pollution is alleviated; the composition is safe to human and livestock and has good environment compatibility, and drug resistance of the diseases is not easy to cause.
Description
The application is divisional application, original application is the patent of invention that Shaanxi Meibang Pesticide Co., Ltd. submits to, original application denomination of invention is " a kind of bactericidal composition containing pyrrole metsulfovax ", and application number is " 201210342423.2 ", and the applying date is: 2012.09.14.
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on corps diseases containing pyrrole metsulfovax.
Background technology
Pyrrole metsulfovax (Penthiopyrad) chemical name: (RS)-N-[2-(1,3-dimethylbutyl)-3-thiophene phenyl]-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide, molecular formula: C
16h
20f
3n
3oS, pyrrole metsulfovax is the novel acid amide fungicides of Mitsui chemical company research and development, it has different fungicidal spectrums from existing carboxyl acylamide bactericide, except the same with existing carboxyl acylamide bactericide to basidiomycetes effectively except, it is also effective to sac fungi, imperfect fungus, existing recommended for preventing and treating gray mold to other bactericide tool resistances and powdery mildew.
Frost urea cyanogen, dimethomorph, Propamocarb or its salt, iprovalicarb, captan, tpn, metalaxyl or its salt all belong to conventional bactericidal composition, be widely used in the disease of crops, wherein the salt of Propamocarb is propamocarb, and the salt of metalaxyl is Metalaxyl-M.
But in the real process of agricultural production, the problem that controlling disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of co-toxicity coefficient.Study through inventor, find by pyrrole metsulfovax and white urea cyanogen, dimethomorph, Propamocarb or its salt, iprovalicarb, captan, tpn, metalaxyl or its salt composite after can produce good synergistic effect, and about pyrrole metsulfovax and the composite relevant report of white urea cyanogen, dimethomorph, Propamocarb or its salt, iprovalicarb, captan, tpn, metalaxyl or its salt not yet open.
Summary of the invention
The object of the invention is to propose a kind of to there is the bactericidal composition containing pyrrole metsulfovax that synergistic function, use cost are low, preventive effect is good.
The bactericidal composition containing pyrrole metsulfovax that the present invention proposes contains active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is selected from pyrrole metsulfovax, active component B is selected from the one in white urea cyanogen, dimethomorph, Propamocarb or its salt, iprovalicarb, captan, tpn, metalaxyl or its salt, and active components A and the preferred weight ratio of active component B are 1 ︰ 60 ~ 40 ︰ 1; The weight ratio being more preferably pyrrole metsulfovax and white urea cyanogen is 1 ︰ 30 ~ 20 ︰ 1, the weight ratio of pyrrole metsulfovax and dimethomorph is 1 ︰ 30 ~ 15 ︰ 1, the weight ratio of pyrrole metsulfovax and Propamocarb or its salt is 1 ︰ 30 ~ 20 ︰ 1, the weight ratio of pyrrole metsulfovax and iprovalicarb is 1 ︰ 30 ~ 30 ︰ 1, the weight ratio of pyrrole metsulfovax and captan is 1 ︰ 30 ~ 20 ︰ 1, the weight ratio of pyrrole metsulfovax and tpn is 1 ︰ 30 ~ 10 ︰ 1, and the weight ratio of pyrrole metsulfovax and metalaxyl or its salt is 1 ︰ 30 ~ 20 ︰ 1; The weight ratio most preferably being pyrrole metsulfovax and white urea cyanogen is 1 ︰ 11 ~ 9 ︰ 1, the weight ratio of pyrrole metsulfovax and dimethomorph is 1 ︰ 14 ~ 9 ︰ 1, the weight ratio of pyrrole metsulfovax and Propamocarb or its salt is 1 ︰ 14 ~ 4 ︰ 1, the weight ratio of pyrrole metsulfovax and iprovalicarb is 1 ︰ 11 ~ 11 ︰ 1, the weight ratio of pyrrole metsulfovax and captan is 1 ︰ 14 ~ 4 ︰ 1, the weight ratio of pyrrole metsulfovax and tpn is 1 ︰ 19 ~ 1 ︰ 1, and the weight ratio of pyrrole metsulfovax and metalaxyl or its salt is 1 ︰ 14 ~ 4 ︰ 1.
Bactericidal composition containing pyrrole metsulfovax of the present invention is for preventing and treating the purposes of disease on crops, and described crops comprise cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; Described disease comprises rust, stalk break, gray mold, downy mildew, spot defoliation, powdery mildew, scab, epidemic disease, peronospora tabacina, balck shank, damping off, leaf mold, anthracnose, ring spot, shot hole, leaf spot, anthrachose of grape, rice blast, banded sclerotial blight.
The weight ratio of active components A, active component B is 1 ︰ 80 ~ 60 ︰ 1.In usual composition, the weight percentage of active component is 0.1% ~ 90% of gross weight, is preferably 5% ~ 70%.According to different preparation types, active component content scope is different.Usually, liquid preparation contains the active substance of by weight 1% ~ 70%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 70%, is preferably 10% ~ 70%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Bactericidal composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by common processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active substance, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer, disintegrant, antifreeze etc.
Bactericidal composition of the present invention, acceptable formulation on any agricultural chemicals can be processed on demand, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent, can also make aqua.
Composition comprises following constituent content when making wetting powder: active components A 1% ~ 60%, active component B1% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
Composition comprises following constituent content when making water dispersible granules: active components A 1% ~ 60%, active component B1% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following constituent content when making suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following constituent content when making suspension emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 1% ~ 15%, thickener 0 ~ 2%, emulsifier 2% ~ 12%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following constituent content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, thickener 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water supply surplus.
Composition comprises following component and content when making microemulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following constituent content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, organic solvent 1% ~ 10%, emulsifier 1% ~ 7%, defoamer 0.01% ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Composition comprises following constituent content when making microcapsule suspension-suspendinagent agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
| Technical indicator | Dispersed | Suspensibility | MEBO ribbon gauze | Fineness (by 45 μm of testing sieves) | Water content |
| The all embodiments of the present invention | ≥90% | ≥90% | ≤ 90 seconds | ≥98% | ≤2% |
| Pesticidal products specification requirement | ≥70% | ≥70% | ≤ 120 seconds | ≥95% | ≤3% |
Water dispersible granules the key technical indexes of the present invention:
| Technical indicator | Dispersed | Suspensibility | MEBO ribbon gauze | Fineness (by 55 μm of testing sieves) | Water content |
| The all embodiments of the present invention | ≥90% | ≥90% | ≤ 70 seconds | ≥99% | ≤1.5% |
| Pesticidal products specification requirement | ≥70% | ≥70% | ≤ 120 seconds | ≥95% | ≤3% |
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
| Technical indicator | Suspensibility | Persistent foamability (after 1 minute) | Topple over rear residue | Heat storage (50 DEG C) stability (active ingredient resolution ratio) | Low temperature (0 DEG C) stability (educt volume) |
| The all embodiments of the present invention | ≥95% | ≤20ml | ≤3% | ≤3% | ≤0.1ml |
| Pesticidal products specification requirement | ≥70% | ≤25ml | ≤5% | ≤5% | ≤0.3ml |
Aqueous emulsion the key technical indexes of the present invention:
| Technical indicator | Persistent foamability (after 1 minute) | Stability of emulsion | Topple over rear residue | Heat storage (50 DEG C) stability (active ingredient resolution ratio) | Low temperature (0 DEG C) stability (educt volume) |
| The all embodiments of the present invention | ≤20ml | Well | ≤1% | ≤3% | ≤0.1ml |
| Pesticidal products specification requirement | ≤25ml | Qualified | ≤3% | ≤5% | ≤0.3ml |
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) pyrrole metsulfovax and white urea cyanogen, dimethomorph, Propamocarb or its salt, iprovalicarb, captan, tpn, metalaxyl or its salt composite after, there is obvious synergy and lasting effect; (2) all greater activity is had to disease on cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; (3) decrease pesticide usage amount, reduce the residual quantity of agricultural chemicals on crop, alleviate environmental pollution; (4) to person poultry safety, Environmental compatibility is good; And preparation adhesion strength strengthens, resistance of rainwater washing against.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1 ~ 17 wetting powder
Pyrrole metsulfovax, active component B, dispersant, wetting agent, filler are mixed in mixed cylinder, mixes again after airslide disintegrating mill is pulverized, wetting powder product of the present invention can be obtained, specifically in table 1.
The each component of table 1 embodiment 1 ~ 17 and weight portion
Embodiment 18 ~ 34 water dispersible granules
Pyrrole metsulfovax, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent (can add and can not add), obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, water dispersible granules product of the present invention can being obtained, specifically in table 2.
The each component of table 2 embodiment 18 ~ 34 and weight portion
By urea cyanogen white in table 1 ~ 2, dimethomorph, Propamocarb or its salt, iprovalicarb, captan, tpn, metalaxyl or its salt interchange, novel formulation can be obtained.
Embodiment 35 ~ 51 suspending agent
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), mix through high speed shear, add pyrrole metsulfovax, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can obtain suspending agent product of the present invention, specifically in table 3.
The each component of table 3 embodiment 35 ~ 51 and weight portion
Urea cyanogen white in table 3, dimethomorph, Propamocarb or its salt, iprovalicarb, captan, tpn, metalaxyl are exchanged, can novel formulation be obtained.
Embodiment 52 ~ 61 suspension emulsion
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add pyrrole metsulfovax, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained pyrrole metsulfovax suspending agent, then by active component B, solvent, emulsifier and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, surplus deionized water is supplied, obtained suspension emulsion product of the present invention, specifically in table 4,5.Each group of table 4 embodiment 52 ~ 56 and weight portion
Each group of table 5 embodiment 57 ~ 61 and weight portion
By urea cyanogen white in table 4,5, dimethomorph, iprovalicarb, captan, tpn, metalaxyl or its salt interchange, novel formulation can be obtained.
Embodiment 62 ~ 78 aqueous emulsion
Pyrrole metsulfovax, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, surplus deionized water is supplied; Aqueous emulsion product of the present invention can be obtained, specifically in table 6.
The each component of table 6 embodiment 62 ~ 78 and weight portion
By urea cyanogen white in table 6, dimethomorph, Propamocarb or its salt, iprovalicarb, captan, tpn, metalaxyl or its salt interchange, novel formulation can be obtained.
Embodiment 79 ~ 81 microemulsion
Pyrrole metsulfovax, active component B are dissolved in and are equipped with in the homogenizer of solvent, emulsifier, antifreeze (can add and can not add), defoamer are joined in the homogenizer that above-mentioned solution is housed, surplus deionized water gives strong mixing and homogenize after supplying, finally obtain the microemulsion product of the present invention that clear appearance is transparent.Specifically in table 7.
The each component of table 7 embodiment 79 ~ 81 and content
Embodiment 82,83 microcapsule suspending agent
By pyrrole metsulfovax, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 8.Table 8 embodiment 82,83 each component and weight portion
Embodiment 84,85 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add pyrrole metsulfovax, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, make the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition, specifically in table 9.
Table 9 embodiment 84,85 each component and weight portion
In table 9, active component B is white urea cyanogen, dimethomorph, iprovalicarb, captan, tpn, metalaxyl or its salt.
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First pass through Toxicity Determination, co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are composite by a certain percentage, CTC < 70 is antagonism, 70≤CTC≤120 are summation action, CTC > 120 is synergistic effect, on this basis, then carry out field trial.
Test method: respectively the mother liquor of each mixed agent is diluted to five series concentration during test, is placed in beaker respectively for subsequent use.Adopt the method connecing bacterium after first soaking leaf, take out after the blade of the same size not contacting any medicament is soaked 5s in the liquid configured, naturally dry, put into bacteria box, then connect for the young bacterium of examination, raise under 25 DEG C of conditions, often process and repeat for 3 times, often repeating examination bacterium number used is 50, establishes blank simultaneously, checks dead bacterium number in 72h, calculate lethality and corrected mortality, try to achieve virulence regression equation and calculate LC
50value.If contrast lethality is greater than 10%, be then considered as invalid test.Computing formula is as follows:
Disease corrected mortality is converted into probit value (y), concentration for the treatment of (μ g/ml) converts logarithm value (x) to, virulence regression equation is drawn with method of least squares, and calculate the value of often kind of medicament thus, calculate co-toxicity coefficient CTC according to the abundant equation of Sun Yun.Computing formula following (with pyrrole metsulfovax for standard agent, its toxicity index is 100):
TI × the P of theoretical toxicity index (the TTI)=pyrrole metsulfovax of M
pyrrole metsulfovax+tI × the P of effective active composition B
effective active composition B
In formula: M is the mixture of different ratio
P
effective active composition Bfor the ratio that effective active composition B is shared in the composition
P
pyrrole metsulfovaxfor the ratio that pyrrole metsulfovax is shared in the composition
B is selected from the one in white urea cyanogen, dimethomorph, Propamocarb or its salt, iprovalicarb, captan, tpn, metalaxyl or its salt.
Application Example two:
For examination disease: downy mildew of garpe; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd.; Experimental scheme: through effective lethal concentration scope of preliminary experiment determination pyrrole metsulfovax and the former medicine of white urea cyanogen and the two different ratio mixture.
Toxicity test result
Table 10 pyrrole metsulfovax and the composite toxicity test analysis of results table to downy mildew of garpe of white urea cyanogen
| Reagent agent | Proportioning | EC 50(mg/L) observed value | EC 50(mg/L) theoretical value | Synergy ratio (SR) |
| Pyrrole metsulfovax | — | 2.15 | — | — |
| Frost urea cyanogen | — | 2.86 | — | — |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 60:1 | 1.15 | 2.16 | 1.88 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 40:1 | 1.11 | 2.16 | 1.95 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 30:1 | 1.08 | 2.17 | 2.01 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 20:1 | 0.98 | 2.18 | 2.22 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 15:1 | 0.97 | 2.18 | 2.25 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 9:1 | 0.94 | 2.20 | 2.35 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 4:1 | 0.92 | 2.26 | 2.46 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 2:3 | 1.00 | 2.53 | 2.53 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 1:5 | 1.11 | 2.71 | 2.44 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 1:11 | 1.19 | 2.78 | 2.34 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 1:20 | 1.25 | 2.82 | 2.25 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 1:30 | 1.27 | 2.83 | 2.23 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 1:40 | 1.40 | 2.84 | 2.03 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 1:60 | 1.48 | 2.84 | 1.92 |
| Pyrrole Sai Jun An ︰ frost urea cyanogen | 1:80 | 1.52 | 2.85 | 1.87 |
As shown in Table 10, pyrrole metsulfovax and white urea cyanogen proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of downy mildew of garpe, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of pyrrole metsulfovax and white urea cyanogen is at 1 ︰ 30 ~ 20 ︰ 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing through applicant the optimum ratio finding pyrrole metsulfovax and white urea cyanogen is 20:1,15:1,10:1,8:1,6:1,5:1,4:1,3:1,2:1,1:1,2:3,1:2,1:3,1:4,1:5,1:6,1:8,1:15,1:20,1:30, especially when pyrrole metsulfovax and white urea cyanogen weight ratio are 2:3, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example three:
For examination disease: cucumber downy mildew; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd.; Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination pyrrole metsulfovax and the former medicine of dimethomorph or different ratio mixture both it.
Toxicity test result
Table 11 pyrrole metsulfovax and the composite toxicity test analysis of results table to cucumber downy mildew of dimethomorph
| Reagent agent | Proportioning | EC 50(mg/L) observed value | EC 50(mg/L) theoretical value | Synergy ratio (SR) |
| Pyrrole metsulfovax | — | 1.90 | — | — |
| Dimethomorph | — | 3.55 | — | — |
| Pyrrole Sai Jun An ︰ dimethomorph | 60:1 | 1.10 | 1.91 | 1.74 |
| Pyrrole Sai Jun An ︰ dimethomorph | 40:1 | 1.02 | 1.92 | 1.88 |
| Pyrrole Sai Jun An ︰ dimethomorph | 25:1 | 0.96 | 1.93 | 2.02 |
| Pyrrole Sai Jun An ︰ dimethomorph | 15:1 | 0.87 | 1.96 | 2.25 |
| Pyrrole Sai Jun An ︰ dimethomorph | 9:1 | 0.82 | 1.99 | 2.43 |
| Pyrrole Sai Jun An ︰ dimethomorph | 4:1 | 0.84 | 2.09 | 2.49 |
| Pyrrole Sai Jun An ︰ dimethomorph | 1:1 | 0.96 | 2.48 | 2.58 |
| Pyrrole Sai Jun An ︰ dimethomorph | 1:2 | 1.05 | 2.75 | 2.62 |
| Pyrrole Sai Jun An ︰ dimethomorph | 1:6 | 1.25 | 3.16 | 2.53 |
| Pyrrole Sai Jun An ︰ dimethomorph | 1:14 | 1.36 | 3.36 | 2.47 |
| Pyrrole Sai Jun An ︰ dimethomorph | 1:20 | 1.47 | 3.41 | 2.32 |
| Pyrrole Sai Jun An ︰ dimethomorph | 1:30 | 1.53 | 3.45 | 2.26 |
| Pyrrole Sai Jun An ︰ dimethomorph | 1:40 | 1.70 | 3.48 | 2.04 |
| Pyrrole Sai Jun An ︰ dimethomorph | 1:60 | 1.81 | 3.50 | 1.93 |
| Pyrrole Sai Jun An ︰ dimethomorph | 1:80 | 1.89 | 3.51 | 1.86 |
As shown in Table 11, pyrrole metsulfovax and dimethomorph proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of cucumber downy mildew, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of pyrrole metsulfovax and dimethomorph is at 1 ︰ 30 ~ 15 ︰ 1, synergistic effect is more obviously given prominence to, and synergy ratio is all more than 2.25.Testing through applicant the optimum ratio finding pyrrole metsulfovax and dimethomorph is 15:1,10:1,8:1,6:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:30, especially when pyrrole metsulfovax and dimethomorph weight ratio are 1:2, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example four:
For examination disease: cucumber downy mildew; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd.; Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination pyrrole metsulfovax and Propamocarb or the former medicine of its salt or different ratio mixture both it.
Toxicity test result
Table 12 pyrrole metsulfovax and Propamocarb or the composite toxicity test analysis of results table to cucumber downy mildew of its salt
| Reagent agent | Proportioning | EC 50(mg/L) observed value | EC 50(mg/L) theoretical value | Synergy ratio (SR) |
| Pyrrole metsulfovax | — | 2.00 | — | — |
| Propamocarb or its salt | — | 8.75 | — | — |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 60:1 | 1.11 | 2.03 | 1.82 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 40:1 | 1.05 | 2.04 | 1.94 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 30:1 | 1.01 | 2.05 | 2.03 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 20:1 | 0.92 | 2.08 | 2.26 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 10:1 | 0.92 | 2.15 | 2.34 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 4:1 | 0.96 | 2.36 | 2.46 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 1:2 | 1.65 | 4.12 | 2.50 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 1:6 | 2.23 | 5.90 | 2.65 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 1:9 | 2.59 | 6.54 | 2.53 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 1:14 | 2.95 | 7.14 | 2.42 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 1:20 | 3.16 | 7.54 | 2.39 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 1:30 | 3.50 | 7.89 | 2.25 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 1:40 | 4.00 | 8.08 | 2.02 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 1:60 | 4.23 | 8.29 | 1.96 |
| Pyrrole Sai Jun An ︰ Propamocarb or its salt | 1:80 | 4.41 | 8.40 | 1.90 |
As shown in Table 12, pyrrole metsulfovax and Propamocarb or its salt proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of cucumber downy mildew, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of pyrrole metsulfovax and Propamocarb or its salt is at 1 ︰ 30 ~ 20 ︰ 1, synergistic effect is more obviously given prominence to, and synergy ratio is all more than 2.25.Testing through applicant the optimum ratio finding pyrrole metsulfovax and Propamocarb or its salt is 20:1,15:1,10:1,6:1,5:1,3:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:11,1:12,1:13,1:14,1:15,1:16,1:20,1:30, especially when pyrrole metsulfovax and Propamocarb or its salt weight ratio are 1:6, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example five:
For examination disease: downy mildew of crucifers; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd.; Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination pyrrole metsulfovax and the former medicine of iprovalicarb or different ratio mixture both it.
Toxicity test result
Table 13 pyrrole metsulfovax and the composite toxicity test analysis of results table to downy mildew of crucifers of iprovalicarb
| Reagent agent | Proportioning | EC 50(mg/L) observed value | EC 50(mg/L) theoretical value | Synergy ratio (SR) |
| Pyrrole metsulfovax | — | 2.10 | — | — |
| Iprovalicarb | — | 2.00 | — | — |
| Pyrrole Sai Jun An ︰ iprovalicarb | 60:1 | 1.13 | 2.10 | 1.86 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 50:1 | 1.07 | 2.10 | 1.96 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 40:1 | 1.05 | 2.10 | 2.00 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 30:1 | 0.94 | 2.10 | 2.23 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 20:1 | 0.91 | 2.10 | 2.30 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 11:1 | 0.87 | 2.09 | 2.40 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 5:1 | 0.85 | 2.08 | 2.45 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 1:1 | 0.82 | 2.05 | 2.50 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 1:5 | 0.83 | 2.02 | 2.43 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 1:11 | 0.84 | 2.01 | 2.39 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 1:20 | 0.88 | 2.00 | 2.28 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 1:30 | 0.89 | 2.00 | 2.25 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 1:40 | 0.99 | 2.00 | 2.02 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 1:60 | 1.03 | 2.00 | 1.94 |
| Pyrrole Sai Jun An ︰ iprovalicarb | 1:80 | 1.08 | 2.00 | 1.85 |
As shown in Table 13, pyrrole metsulfovax and iprovalicarb proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of downy mildew of crucifers, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of pyrrole metsulfovax and iprovalicarb is at 1 ︰ 30 ~ 30 ︰ 1, synergistic effect is more obviously given prominence to, synergy ratio is all more than 2.20, and especially when pyrrole metsulfovax and iprovalicarb weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example six:
For examination disease: grey mould fruit rot of strawberry; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination pyrrole metsulfovax and the former medicine of captan or different ratio mixture both it.
Toxicity test result
Table 14 pyrrole metsulfovax and the composite toxicity test analysis of results table to grey mould fruit rot of strawberry of captan
| Reagent agent | Proportioning | EC 50(mg/L) observed value | EC 50(mg/L) theoretical value | Synergy ratio (SR) |
| Pyrrole metsulfovax | — | 2.05 | — | — |
| Captan | — | 9.00 | — | — |
| Pyrrole Sai Jun An ︰ captan | 60:1 | 1.12 | 2.08 | 1.85 |
| Pyrrole Sai Jun An ︰ captan | 40:1 | 1.06 | 2.09 | 1.97 |
| Pyrrole Sai Jun An ︰ captan | 30:1 | 1.05 | 2.10 | 2.00 |
| Pyrrole Sai Jun An ︰ captan | 20:1 | 0.95 | 2.13 | 2.24 |
| Pyrrole Sai Jun An ︰ captan | 10:1 | 0.94 | 2.20 | 2.35 |
| Pyrrole Sai Jun An ︰ captan | 4:1 | 0.99 | 2.42 | 2.45 |
| Pyrrole Sai Jun An ︰ captan | 1:2 | 1.67 | 4.23 | 2.53 |
| Pyrrole Sai Jun An ︰ captan | 1:6 | 2.28 | 6.06 | 2.66 |
| Pyrrole Sai Jun An ︰ captan | 1:9 | 2.65 | 6.72 | 2.54 |
| Pyrrole Sai Jun An ︰ captan | 1:14 | 3.00 | 7.34 | 2.45 |
| Pyrrole Sai Jun An ︰ captan | 1:20 | 3.26 | 7.75 | 2.38 |
| Pyrrole Sai Jun An ︰ captan | 1:30 | 3.67 | 8.11 | 2.21 |
| Pyrrole Sai Jun An ︰ captan | 1:40 | 4.09 | 8.31 | 2.03 |
| Pyrrole Sai Jun An ︰ captan | 1:60 | 4.28 | 8.53 | 1.99 |
| Pyrrole Sai Jun An ︰ captan | 1:80 | 4.57 | 8.64 | 1.89 |
As shown in Table 14, pyrrole metsulfovax and captan proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of grey mould fruit rot of strawberry, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of pyrrole metsulfovax and captan is at 1 ︰ 30 ~ 20 ︰ 1, synergistic effect is more obviously given prominence to, synergy ratio is all more than 2.20, and especially when pyrrole metsulfovax and captan weight ratio are 1:6, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example seven:
For examination disease: powdery mildew of cucumber; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination pyrrole metsulfovax and the former medicine of tpn or different ratio mixture both it.
Table 15 pyrrole metsulfovax and chlorothalonil compound are to the toxicity test analysis of results table of powdery mildew of cucumber
| Reagent agent | Proportioning | EC 50(mg/L) observed value | EC 50(mg/L) theoretical value | Synergy ratio (SR) |
| Pyrrole metsulfovax | — | 1.95 | — | — |
| Tpn | — | 9.88 | — | — |
| Pyrrole Sai Jun An ︰ tpn | 60:1 | 1.10 | 1.98 | 1.80 |
| Pyrrole Sai Jun An ︰ tpn | 40:1 | 1.05 | 1.99 | 1.89 |
| Pyrrole Sai Jun An ︰ tpn | 30:1 | 1.01 | 2.00 | 1.98 |
| Pyrrole Sai Jun An ︰ tpn | 20:1 | 0.99 | 2.03 | 2.05 |
| Pyrrole Sai Jun An ︰ tpn | 10:1 | 0.93 | 2.10 | 2.26 |
| Pyrrole Sai Jun An ︰ tpn | 1:1 | 1.32 | 3.26 | 2.47 |
| Pyrrole Sai Jun An ︰ tpn | 1:5 | 2.32 | 5.89 | 2.54 |
| Pyrrole Sai Jun An ︰ tpn | 1:10 | 2.69 | 7.21 | 2.68 |
| Pyrrole Sai Jun An ︰ tpn | 1:15 | 3.10 | 7.88 | 2.54 |
| Pyrrole Sai Jun An ︰ tpn | 1:19 | 3.38 | 8.21 | 2.43 |
| Pyrrole Sai Jun An ︰ tpn | 1:25 | 3.59 | 8.54 | 2.38 |
| Pyrrole Sai Jun An ︰ tpn | 1:30 | 3.87 | 8.73 | 2.26 |
| Pyrrole Sai Jun An ︰ tpn | 1:40 | 4.41 | 8.99 | 2.04 |
| Pyrrole Sai Jun An ︰ tpn | 1:60 | 4.85 | 9.26 | 1.91 |
| Pyrrole Sai Jun An ︰ tpn | 1:80 | 5.00 | 9.41 | 1.88 |
As shown in Table 15, pyrrole metsulfovax and tpn proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of powdery mildew of cucumber, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of pyrrole metsulfovax and tpn is at 1 ︰ 30 ~ 10 ︰ 1, synergistic effect is more outstanding, synergy ratio is all more than 2.25, and especially when pyrrole metsulfovax and tpn weight ratio are 1:10, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example eight:
For examination disease: cucumber downy mildew; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd.; Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination pyrrole metsulfovax and metalaxyl or the former medicine of its salt or different ratio mixture both it.
Toxicity test result
Table 16 pyrrole metsulfovax and metalaxyl or the composite toxicity test analysis of results table to cucumber downy mildew of its salt
| Reagent agent | Proportioning | EC 50(mg/L) observed value | EC 50(mg/L) theoretical value | Synergy ratio (SR) |
| Pyrrole metsulfovax | — | 2.00 | — | — |
| Metalaxyl or its salt | — | 8.55 | — | — |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 60:1 | 1.11 | 2.03 | 1.82 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 40:1 | 1.05 | 2.04 | 1.94 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 30:1 | 1.01 | 2.05 | 2.03 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 20:1 | 0.94 | 2.08 | 2.21 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 10:1 | 0.93 | 2.15 | 2.31 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 4:1 | 0.95 | 2.36 | 2.49 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 1:1 | 1.29 | 3.24 | 2.51 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 1:5 | 2.10 | 5.53 | 2.63 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 1:9 | 2.56 | 6.44 | 2.52 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 1:14 | 2.90 | 7.02 | 2.42 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 1:20 | 3.19 | 7.40 | 2.32 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 1:30 | 3.50 | 7.73 | 2.21 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 1:40 | 3.95 | 7.92 | 2.00 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 1:60 | 4.10 | 8.11 | 1.98 |
| Pyrrole Sai Jun An ︰ metalaxyl or its salt | 1:80 | 4.38 | 8.22 | 1.88 |
As shown in Table 16, pyrrole metsulfovax and metalaxyl or its salt proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of cucumber downy mildew, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of pyrrole metsulfovax and metalaxyl or its salt is at 1 ︰ 30 ~ 20 ︰ 1, synergistic effect is more obviously given prominence to, synergy ratio is all more than 2.20, and especially when pyrrole metsulfovax and metalaxyl or its salt weight ratio are 1:5, synergy ratio is maximum, and synergistic effect is the most obvious.
Through test find: pyrrole metsulfovax and active component B composite after have obvious synergistic effect to the control of the rust in various crop, stalk break, gray mold, downy mildew, spot defoliation, powdery mildew, scab, epidemic disease, peronospora tabacina, balck shank, damping off, leaf mold, anthracnose, ring spot, shot hole, leaf spot, anthrachose of grape, rice blast, banded sclerotial blight, synergy ratio SR is all greater than 1.5.
Effect experiment part: test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, contrast medicament 20% pyrrole metsulfovax suspending agent (autogamy), 30% white urea cyanogen wetting powder (autogamy), 50% dimethomorph wetting powder (autogamy), 35% Propamocarb aqua (commercial), 5.5% iprovalicarb wetting powder (autogamy), 50% captan wetting powder (commercial), 75% tpn wetting powder (commercial), 35% metalaxyl wetting powder (autogamy).
Application Example nine pyrrole metsulfovax and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation cucumber downy mildew disease index before medicine, in the dispenser of disease initial stage of origination, 3 days, 10 days, 20 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 17 pyrrole metsulfovax and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
As can be seen from Table 17, pyrrole metsulfovax and active component B composite after effectively can prevent and treat cucumber downy mildew, through applicant test find pyrrole metsulfovax and active component B composite after also can effectively prevent and treat gray mold of cucumber, epidemic disease, damping off, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten pyrrole metsulfovax and active component B and the composite control graw mold of tomato test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation graw mold of tomato disease index before medicine, in the dispenser of disease initial stage of origination, 5 days, 15 days, 30 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 18 pyrrole metsulfovax and active component B and the composite control graw mold of tomato test of pesticide effectiveness thereof
As can be seen from Table 18, pyrrole metsulfovax and active component B composite after effectively can prevent and treat graw mold of tomato, through applicant test find pyrrole metsulfovax and active component B composite after also can effectively prevent and treat tomato blight, leaf mold, control efficiency is all higher than 95%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 pyrrole metsulfovax and active component B and the composite control rice blast test of pesticide effectiveness thereof
This test arrangement is in Hanzhong City suburb, Shaanxi Province, and investigation rice blast disease index before medicine, in the dispenser of disease initial stage of origination, 3 days, 10 days, 20 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 19 pyrrole metsulfovax and active component B and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 19, pyrrole metsulfovax and active component B and composite control rice blast thereof, through applicant test find pyrrole metsulfovax and active component B composite after also can the effective water prevention rice sheath blight, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 12 pyrrole metsulfovax and active component B and compositely prevent and treat the wheat rust test of pesticide effectiveness
This test arrangement is in Weinan City Pucheng County, Shaanxi Province, and investigation wheat rust disease index before medicine, in the dispenser of disease initial stage of origination, 1 day, 5 days, 15 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 20 pyrrole metsulfovax and active component B and compositely prevent and treat the wheat rust test of pesticide effectiveness
As can be seen from Table 20, pyrrole metsulfovax and active component B composite after effectively can prevent and treat wheat rust, through applicant test find pyrrole metsulfovax and active component B composite after also can effectively prevent and treat speckled leaf blotch, powdery mildew, control efficiency is all higher than 95%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 13 pyrrole metsulfovax and active component B and the composite control sclerotinia rot of colza test of pesticide effectiveness thereof
This test arrangement is at Xianyang, Shanxi province suburban area, and investigation sclerotinia rot of colza disease index before medicine, in the dispenser of disease initial stage of origination, 3 days, 10 days, 20 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 21 pyrrole metsulfovax and active component B and the composite control sclerotinia rot of colza test of pesticide effectiveness thereof
As can be seen from Table 21, pyrrole metsulfovax and active component B composite after effectively can prevent and treat sclerotinia rot of colza, through applicant test find pyrrole metsulfovax and active component B composite after also can effectively prevent and treat rape balck shank, control efficiency is all higher than 95%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 14 pyrrole metsulfovax and active component B and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Weinan City Baishui County, and investigation alternaria leaf spot of apple disease index before medicine, in the dispenser of disease initial stage of origination, 5 days, 15 days, 30 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 22 pyrrole metsulfovax and active component B and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
As can be seen from Table 22, pyrrole metsulfovax and active component B composite after effectively can prevent and treat alternaria leaf spot of apple, through applicant test find pyrrole metsulfovax and active component B composite after also can effectively prevent and treat apple mildew, scab, anthracnose, ring spot, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 15 pyrrole metsulfovax and active component B and compositely prevent and treat the downy mildew of garpe test of pesticide effectiveness
This test arrangement is in Weinan City Dali County, Shaanxi Province, and investigation downy mildew of garpe disease index before medicine, in the dispenser of disease initial stage of origination, 5 days, 15 days, 30 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 23 pyrrole metsulfovax and active component B and compositely prevent and treat the downy mildew of garpe test of pesticide effectiveness
As can be seen from Table 23, pyrrole metsulfovax and active component B composite after effectively can prevent and treat downy mildew of garpe, through applicant test find pyrrole metsulfovax and active component B composite after also can effectively prevent and treat grape powdery mildew, anthrachose of grape, gray mold, control efficiency is all higher than 95%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, pyrrole metsulfovax and the composite rear preventive effect to Common Diseases such as the rust in various crop, stalk break, gray mold, downy mildew, spot defoliation, powdery mildew, scab, epidemic disease, peronospora tabacina, balck shank, damping off, leaf mold, anthracnose, ring spot, shot hole, leaf spot, anthrachose of grape, rice blast, banded sclerotial blights of active component B are all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the bactericidal composition containing pyrrole metsulfovax, effective active composition is active components A and active component B, it is characterized in that: active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is pyrrole metsulfovax, and active component B is selected from the one in Propamocarb or its salt, iprovalicarb, captan, tpn, metalaxyl or its salt.
2. the bactericidal composition containing pyrrole metsulfovax according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 60 ~ 40 ︰ 1.
3. the bactericidal composition containing pyrrole metsulfovax according to claim 2, is characterized in that:
The weight ratio of pyrrole metsulfovax and Propamocarb or its salt is 1 ︰ 30 ~ 20 ︰ 1;
The weight ratio of pyrrole metsulfovax and iprovalicarb is 1 ︰ 30 ~ 30 ︰ 1;
The weight ratio of pyrrole metsulfovax and captan is 1 ︰ 30 ~ 20 ︰ 1;
The weight ratio of pyrrole metsulfovax and tpn is 1 ︰ 30 ~ 10 ︰ 1;
The weight ratio of pyrrole metsulfovax and metalaxyl or its salt is 1 ︰ 30 ~ 20 ︰ 1.
4. the bactericidal composition containing pyrrole metsulfovax according to any one of claim 1 to 3, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
5. the bactericidal composition containing pyrrole metsulfovax according to claim 4 is for preventing and treating the purposes of disease on crops.
6. purposes according to claim 5, is characterized in that: described disease comprises rust, stalk break, gray mold, downy mildew, spot defoliation, powdery mildew, scab, epidemic disease, peronospora tabacina, balck shank, damping off, leaf mold, anthracnose, ring spot, shot hole, leaf spot, anthrachose of grape, rice blast, banded sclerotial blight.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210342423.2A CN103651472A (en) | 2012-09-14 | 2012-09-14 | Bactericidal composition containing penthiopyrad |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210342423.2A Division CN103651472A (en) | 2012-09-14 | 2012-09-14 | Bactericidal composition containing penthiopyrad |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105145584A true CN105145584A (en) | 2015-12-16 |
Family
ID=50291189
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210342423.2A Pending CN103651472A (en) | 2012-09-14 | 2012-09-14 | Bactericidal composition containing penthiopyrad |
| CN201510556103.0A Pending CN105145584A (en) | 2012-09-14 | 2012-09-14 | Sterilization composition containing penthiopyrad |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210342423.2A Pending CN103651472A (en) | 2012-09-14 | 2012-09-14 | Bactericidal composition containing penthiopyrad |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN103651472A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105475340A (en) * | 2015-12-28 | 2016-04-13 | 南京华洲药业有限公司 | Bactericidal composition containing silthiopham and metalaxyl and application thereof |
| CN107980786A (en) * | 2018-01-18 | 2018-05-04 | 兴农药业（中国）有限公司 | A kind of composition pesticide containing pyrrole metsulfovax and its application |
| CN113317319A (en) * | 2021-06-21 | 2021-08-31 | 青岛瀚生生物科技股份有限公司 | Composite bactericide and application thereof |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105851058A (en) * | 2015-01-21 | 2016-08-17 | 陕西汤普森生物科技有限公司 | Sterilization composition containing captan and copper preparation |
| CN107535255A (en) * | 2017-07-31 | 2018-01-05 | 黔西南州凌飞中草药开发有限公司 | A kind of method for preventing and treating loquat leaf spot disease |
| CN107691460A (en) * | 2017-10-12 | 2018-02-16 | 深圳诺普信农化股份有限公司 | bactericidal composition |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11302109A (en) * | 1998-04-24 | 1999-11-02 | Mitsui Chem Inc | Composition of plant disease injury controlling agent |
| CN101106903A (en) * | 2005-02-04 | 2008-01-16 | 三井化学株式会社 | Plant pathogen control composition and method |
| CN101222847A (en) * | 2005-07-21 | 2008-07-16 | 巴斯福股份公司 | Fungicidally active agent |
-
2012
- 2012-09-14 CN CN201210342423.2A patent/CN103651472A/en active Pending
- 2012-09-14 CN CN201510556103.0A patent/CN105145584A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11302109A (en) * | 1998-04-24 | 1999-11-02 | Mitsui Chem Inc | Composition of plant disease injury controlling agent |
| CN101106903A (en) * | 2005-02-04 | 2008-01-16 | 三井化学株式会社 | Plant pathogen control composition and method |
| CN101222847A (en) * | 2005-07-21 | 2008-07-16 | 巴斯福股份公司 | Fungicidally active agent |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105475340A (en) * | 2015-12-28 | 2016-04-13 | 南京华洲药业有限公司 | Bactericidal composition containing silthiopham and metalaxyl and application thereof |
| CN107980786A (en) * | 2018-01-18 | 2018-05-04 | 兴农药业（中国）有限公司 | A kind of composition pesticide containing pyrrole metsulfovax and its application |
| CN113317319A (en) * | 2021-06-21 | 2021-08-31 | 青岛瀚生生物科技股份有限公司 | Composite bactericide and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103651472A (en) | 2014-03-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103416414A (en) | Bactericidal composition containing Xemium and antibiotics | |
| CN104996431A (en) | Efficient insecticidal composition comprising propylene glycol alginate | |
| CN105145584A (en) | Sterilization composition containing penthiopyrad | |
| CN104336079A (en) | A compound sterilization composition containing oxathiapiprolin | |
| CN104412981A (en) | Antibacterial composition containing fluoride ether bacteria amide and strobilurin | |
| CN103518770B (en) | Bactericidal composition containing fluopyram and triazole | |
| CN103651538B (en) | A kind of bactericidal composition containing zoxamide | |
| CN104336033A (en) | A compound sterilization composition containing oxathiapiprolin and thiocarbamate | |
| CN104886064A (en) | Sterilization composite containing N-(2-trifluoromethyl-4-chlorphenyl)-2-oxocyclohexyl sulfonamide | |
| CN104996432A (en) | Sterilization composition containing penthiopyrad and methoxyl acrylic esters | |
| CN103651451A (en) | Pesticide composition containing penthiopyrad | |
| CN103651363B (en) | Pesticidal composition containing spiromesifen and nereistoxin | |
| CN104222118B (en) | A kind of bactericidal composition | |
| CN104642346A (en) | High-efficient bactericidal composition containing zinc thiazole | |
| CN104285954A (en) | Efficient fungicidal composition | |
| CN104126585A (en) | Compound bactericidal composition containing penflufen | |
| CN104886092A (en) | Pesticide composition containing penthiopyrad | |
| CN103518727B (en) | A kind of bactericidal composition of containing fluopyram | |
| CN104509534A (en) | Insect disinfestation composition containing trifluorobenzene pyrimidine and nereistoxin | |
| CN103931620A (en) | Insecticidal composition containing silvchongxian'an and nereistoxin insecticide | |
| CN104115830A (en) | Insecticidal composition containing flubendiamide and nereistoxin | |
| CN105284806A (en) | Sterilization composition containing zoxamide and strobilurin | |
| CN103416416B (en) | A kind of bactericidal composition containing tiadinil | |
| CN103583541B (en) | A kind of bactericidal composition containing Fenarimol | |
| CN103621527B (en) | Sterilization composition containing cyclohexyl flusulfamide |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20151216 |