CN103405498B - A kind of compound antihyperglycemic ball - Google Patents
A kind of compound antihyperglycemic ball Download PDFInfo
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- CN103405498B CN103405498B CN201310263895.3A CN201310263895A CN103405498B CN 103405498 B CN103405498 B CN 103405498B CN 201310263895 A CN201310263895 A CN 201310263895A CN 103405498 B CN103405498 B CN 103405498B
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Abstract
A kind of compound antihyperglycemic ball provided by the invention, raw material by Herba Carpesii Cernui 15-25 part, lavandula angustifolia 15-25 part, the real 12-22 part of coriander, Cuscuta 8-15 part, terminalia flesh 25-45 part, the sub-12-25 part of witloof, seed of Herba Apii graveolentis 12-20 part forms; Above-mentioned raw materials is placed in pulverizer pulverize, after 80 orders that sieve, obtained mixed powder; Take honey, it is placed in furnace pot and is heated to boil, filter and abandon foam, obtained refining honey; Honey will be refined mix by 1:1 with medicinal powder while hot, and be placed in stirrer and mix conjunction evenly, patent medicine group, then medicine group will be placed in the obtained finished product pill of the desk-top pellet processing machine of 0.3g, pack with high-density polyethylene bottle. This compound antihyperglycemic ball, warm water is oral after meal, a 7-9 ball, 2 times on the one, treatment hypertension and hyperlipidemia excellent.
Description
Technical field
The present invention relates to Uygur's Chinese herbal pill, formula is classical, has outstanding prevention and curative effect, the dark accreditation by patient.
Background technology
The Herba Carpesii Cernui medicine selected in prescription is adopted, in China Xinjiang, USSR (Union of Soviet Socialist Republics), also there is distribution in Europe etc., pharmacology: heliotrine has antitumor action, neuroganglion is had blocking effect when 10 mg/kg by Retrochalcone, the instant embrane contraction that the sympathetic preganglionic fiber of electricity irritation causes can be blocked completely, the boosting of suprarenin can be strengthened. The cultivation of lavandula angustifolia Xinjiang is more, Jiangsu has introduces a fine variety on a small quantity, pharmacology: stem leaf and oil can make sanitas, treatment is scalded, burn, ulcer, neurodynia, tetter, among the people to bathe agent treatment rheumatism, oil can be made the stimulant that relaxes and carminative and staphylococcus, suis and sarcina are had restraining effect. Yuan is appropriate, and there is cultivation all parts of the country, pharmacology: dry mature fruit, for relaxing perfume compound, has certain antibechic, eliminates the phlegm and antiasthmatic effect. To lung coccus, streptococcus aureus has restraining effect. There is distribution Cuscuta major part provinces and regions, pharmacology: to streptococcus aureus, Corynebacterium diphtheriae has restraining effect. Terminalia flesh, is born in height above sea level 540 1350 meters of hillside area without shade and sparse woods, and Yunnan Province of China has distribution; Pharmacology: anti-microbial effect, first rushes down and restrains afterwards. All there is distribution various places, witloof sub-Xinjiang, pharmacology: have antibacterial, anti-inflammation, converging action. The seed of Herba Apii graveolentis whole nation and all have a cultivation, pharmacology all over the world: antibacterial, step-down, stable effect, and toxicity is lower. Fructus Terminaliae Billericae Yunnan Province of China has distribution, pharmacology: anti-microbial effect, first rushes down and restrains afterwards.
The present invention has drawn from the effective constituent of above-mentioned numerous medicinal material, and enforcement science is prepared and made pill, and its curative effect does not say and language, is the excavation of resource quality and the utilization of ethnic drug, has expanded new thinking. Summary of the invention
It is an object of the invention to: the pill prescription prepared is classical, to brain refreshing and eyesight improving, pain relieving, for poor or weak eyesight nyctalopia, headache, has unique curative effect, by patient is favored.
The object of the present invention is achieved like this: a kind of compound antihyperglycemic ball, and raw material is prepared with weight fraction, implements step by step;
Step 1 feed composition: by Herba Carpesii Cernui 15-25 part, lavandula angustifolia 15-25 part, the real 12-22 part of coriander, Cuscuta 8-15 part, terminalia flesh 25-45 part, the sub-12-25 part of witloof, seed of Herba Apii graveolentis 12-20 part forms; Above-mentioned raw materials is placed in pulverizer pulverize, after 80 orders that sieve, obtained mixed powder;
Step 2 refines honey: take honey, is placed in furnace pot and is heated to boil, and filters and abandons foam, obtained refining honey;
Step 3 closes medicine: mixed by 1:1 with the medicinal powder of step 1 while hot by the refining of step 2 honey, is placed in stirrer and mixes conjunction evenly, and patent medicine group is for subsequent use;
Step 4 obtains pill: the medicine group of step 3 is placed in the obtained finished product of the desk-top pellet processing machine of 0.3g, packs with high-density polyethylene bottle.
Described compound antihyperglycemic ball, warm water is oral after meal, a 7-9 ball, 2 times on the one.
The pharmacological action of present inventive concept: seed of Herba Apii graveolentis, property is xeothermic, cures mainly invigorating brain and relieving mental uneasiness, promoting blood circulation to restore menstrual flow, wind-damp dispelling. Lavandula angustifolia is warm in nature, cures mainly profit wet, and stomach invigorating, clear brain, except chill. Cold two grades of the appropriate one-level of Yuan is done, and Xin Wen, cures mainly: causing resuscitation with aromatic drugs, stomach strengthening and digestion promoting, anticorrosion pain relieving, kobadrin, promoting eruption sweating. Cuscuta is put down, tepor, invigorating the liver and kidney, benefit marrow, and energy heat-clearing, cough-relieving. Terminalia flesh one-level heat three grades is done, and tonifying the spleen and stomach is aid digestion, tranquilizing and allaying excitement, relieving diarrhea with astringents blood, step-down; Witloof, cures mainly: clearing heat and detoxicating, inducing diuresis to remove edema, food digesting stomach fortifying. Root of Common Houndstongue is put down, and cures mainly clearing heat and detoxicating, the clear brain of step-down, and owing to headache is dizzy, hypertension, poor memory, asthma due to excessive phlegm is coughed, the diseases such as neurasthenia. Pill of the present invention is to treatment, preventing hypertension, and hyperlipidemia, neurasthenia, insomnia has unique curative effect, shows technical progress.
Embodiment
Below in conjunction with embodiment, invention is described further.
Embodiment
One, pill preparation:
1) feed composition:
1 group: get Herba Carpesii Cernui 15 parts, lavandula angustifolia 15 parts, real 12 parts of coriander, Cuscuta 8 parts, terminalia flesh 25 parts, witloof 12 parts, seed of Herba Apii graveolentis 12 parts;
2 groups: get Herba Carpesii Cernui 25 parts, lavandula angustifolia 25 parts, real 22 parts of coriander, Cuscuta 15 parts, terminalia flesh 45 parts, witloof 25 parts, seed of Herba Apii graveolentis 20 parts;
3 groups: get Herba Carpesii Cernui 20 parts, lavandula angustifolia 20 parts, real 18 parts of coriander, Cuscuta 12 parts, terminalia flesh 35 parts, witloof 18 parts, seed of Herba Apii graveolentis 16 parts;
By above-mentioned 1,2,3 group of its group of raw material optional, it is placed in pulverizer and pulverizes, after 80 orders that sieve, obtained mixed powder;
2) refining honey: the honey taking requirement is heated to boil (can filter if any impurity) in furnace pot, continues to refine into refining honey degree, drags for floating foam strip glossy.
3) medicine is closed: mixed by 1:1 with medicinal powder by the refining refined honey, can mechanically mixing or manually mix; Refining honey evenly is integrated with medicinal powder, does patent medicine group; When closing medicine, honey generally adds (as added mixing again after refining honey is slightly cold containing colloid, resin or volatile component) while hot, and summer measures few with honey, and winter is many by honey amount, abundant and even so that it is neither too hard, nor too soft, can arbitrarily pinch and mould.
4) bar processed, become ball: the dough sample softwood that get togather is placed certain time, medicine material mix with honey component moist, when ball made by machinery, obtained with desk-top 0.3g pellet processing machine, pack with high-density polyethylene bottle; During manual ball processed, first medicine agglomerate is weighed, calculate by the total amount of the number and every ball of making ball grain needed for each, be first twisted into bar and be divided into segment again, be twisted into spherical; For avoiding the sticky hand of medicine group and sticking device tool, can with appropriate sesame oil or peanut oil during operation, beeswax, heat fused uses.
5) packaging and storage: the honeyed bolus made, adopts paraffin paper, glassine paper, plastics bag, wax shell packaging, and indicate the name of an article, lot number, specification, is stored in shady and cool dry place.
Two, result for the treatment of checking:
Treatment hypertension patient 52 people, medication one month, complete more person 33 people, improvement person 12 people, invalid person 9 people; Treatment hyperlipemic patients 56 people, Quan Yuzhe, 34 people, improvement person 13 people, invalid person 9 people; Treatment neurasthenia is had a sleepless night 51 people, complete more person 27 people, improvement person 14 people, invalid person 10 people.
Patients with hypertension medication effect sees the following form 1.
Table 1
Hyperlipemia medication effect is in table 2.
Table 2
Insomnia, neurasthenia patient medication effect are in table 3.
Table 3
Case definition: adopt 1) blood-fat analyser inspection diagnosis. 2) blood pressure measuring blood pressure inspection diagnosis.
The pill of this product meets that (" Chinese Pharmacopoeia " version in 2010 annex IA specifies.
(2) result for the treatment of is put to the proof:
Hyperlipidemia treatment case:
Bai Keli, 38 years old man. On March 10th, 2008, blood triglyceride: 3.57mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.83mmol, and illness heals entirely, and after six months, check is without recurrence.
Ku Erban, 60 years old, man. On March 18th, 2008, blood triglyceride: 2.48mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.83mmol, and illness heals entirely, without recurrence.
Sub-gloomy, 58 years old, man. On March 21st, 2008, blood triglyceride: 3.21mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.78mmol, and illness heals entirely, and after six months, check is without recurrence.
Ai Li, 28, man. On March 22nd, 2008, blood triglyceride: 3.87mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 40 days is 1.82mmol, and illness heals entirely. Without recurrence.
Heat diligent ten thousand, 60 years old, female. On April 5th, 2008, blood triglyceride: 2.70mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.82mmol, and illness heals entirely, and after six months, check is without recurrence.
Sha Liman, 56 is dead, female. On April 10th, 2008, blood triglyceride: 2.20mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.80mmol, and illness heals entirely, and after six months, check is without recurrence.
A Yixia order, 37 years old, female. On May 12nd, 2008, blood triglyceride: 2.15mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.82mmol, and illness heals entirely, and after six months, check is without recurrence.
Breathe out the beautiful dawn, 38 years old, female. In March, 2009, blood triglyceride: 2.15mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.72mmol, and illness heals entirely, and after six months, check is without recurrence.
Mai Likai, 41 years old, female. In May, 2009, blood triglyceride: 2.37mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.68mmol, and illness heals entirely, and after six months, check is without recurrence.
Ai Erfa, 40 years old, man. In February, 2010, blood triglyceride: 3.15mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.82mmol, and illness heals entirely, and after six months, check is without recurrence.
Wood is husky, 50 years old, man. In March, 2010, blood triglyceride: 2.25mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.78mmol, and illness heals entirely, and after six months, check is without recurrence.
Ai Kebaier, 52 years old, man. In May, 2010, blood triglyceride: 2.40mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.71mmol, and illness heals entirely, and after six months, check is without recurrence.
Jerry power, 48 years old, man, in June, 2010, blood triglyceride: 2.30mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.76mmol, and illness heals entirely, and after six months, check is without recurrence.
Card Deere, 55 years old, man. 20108 months, blood triglyceride: 3.20mmol; This medicine 2 times on the one, 7 balls, warm water is taken after meal, and checking triglyceride after serveing on 30 days is 1.81mmol, and illness heals entirely, and after six months, check is without recurrence.
Vascular hypertension treatment case:
Ali's wood, 65 years old, man. On March 25th, 2009, blood pressure measuring blood pressure: 165/100mmHg; This medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 140/90mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, and 7 balls, serve on, and after six months, check is normal.
Salad wood, 60 years old, man. On March 28th, 2009, blood pressure measuring blood pressure: 160/95mmHg; This medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 135/85mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, and 7 balls, serve on, and after six months, check is normal.
Hot west is carried, 68 years old, man. On April 21st, 2009, blood pressure measuring blood pressure: 180/105mmHg; This medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 140/90mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, and 7 balls, serve on, and after six months, check is normal.
A Liya, 55 years old, female. On May 18th, 2009, blood pressure measuring blood pressure: 160/95mmHg; This medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 130/85mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, and 7 balls, serve on, and after six months, check is normal.
Chinese mugwort is bought jointly and carries, 58 years old, man. On August 15th, 2009, blood pressure measuring blood pressure: 170/100mmHg; This medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 140/85mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, and 7 balls, serve on, and after six months, check is normal.
Ai Lika wood, 50 years old, man. On October 26th, 2009, blood pressure measuring blood pressure: 165/100mmHg, poor sleep; This medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 140/90mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, and 7 balls, serve on, and after six months, check is normal.
Tell your inferior sweat, 55 years old, female. On December 10th, 2009, blood pressure measuring blood pressure: 160/95mmHg, poor sleep, this medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 120/80mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, 7 balls, serve on, and after six months, check is normal.
Nu Sire carries, 58 years old female, on February 28th, 2010, blood pressure measuring blood pressure: 165/100mmHg, poor sleep, this medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 140/90mmHg, illness takes a turn for the better, after 10 days 1 time on the one, 7 balls, serveing on, after six months, check is normal.
Block this wood, 48 years old, man. In March, 2008, blood pressure measuring blood pressure: 155/100mmHg, poor sleep, this medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 140/90mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, 7 balls, serve on, and after six months, check is normal.
I must be hot, 51 years old, man. In April, 2009, blood pressure measuring blood pressure: 160/100mmHg, poor sleep, this medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 135/90mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, 7 balls, serve on, and after six months, check is normal.
Ai Kere wood, 56 years old, man. In May, 2009, blood pressure measuring blood pressure: 160/100mmHg, poor sleep, this medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 135/90mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, 7 balls, serve on, and after six months, check is normal.
Wood under A Yi, 48 years old, female. In February, 2010, blood pressure measuring blood pressure: 160/95mmHg, poor sleep, this medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 125/80mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, and 7 balls, serve on, and after six months, check is normal.
Heat is beautiful according to sweat Gu, 44 years old, female. In March, 2010, blood pressure measuring blood pressure: 170/100mmHg, poor sleep, this medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 140/90mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, 7 balls, serve on, and after six months, check is normal.
My pul, 60 years old, man. In September, 2010, blood pressure measuring blood pressure: 165/95mmHg, poor sleep, this medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 135/85mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, and 7 balls, serve on, and after six months, check is normal.
A Bu draws, 62 years old, man. In December, 20010, blood pressure measuring blood pressure: 165/100mmHg, poor sleep, this medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 135/90mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, 7 balls, serve on, and after six months, check is normal.
Ah 's wood sweat, 45 years old, female. In December, 2010, blood pressure measuring blood pressure: 170/105mmHg, poor sleep, this medicine 2 times on the one, 7 balls, warm water is taken after meal, serve on 10 days, blood pressure: 140/90mmHg, and illness takes a turn for the better, after 10 days 1 time on the one, 7 balls, serve on, and after six months, check is normal.
Above-mentioned 15 patients 2008 to 2010 analyze, and this medicine is after warm water is taken after meal, hyperlipidemia, hypertension, and the illness such as have a sleepless night not good has obvious curative effect.
Case definition:
1) blood-fat analyser inspection diagnosis is adopted; The normal value of adult's total cholesterol: 2.9-6.0mmol/L; The normal value 0.56-1.7mmol/L of triglyceride level; Recommend the male sex in the world: 0.45-1.7m.
Hyperlipidaemia: metabolism of fat or running make one or more lipids of blood plasma higher than being normally called hyperlipidemia extremely. Hyperlipidemia is a kind of systemic disease, refers to total cholesterol in blood (TC) and/or triglyceride level (TG) is too high or high density lipoprotein cholesterol (HDL-C) is too low, and modern medicine is referred to as hyperlipemia. Lipid is insoluble or is slightly soluble in water, it is necessary to exist with lipoprotein form with protein bound, and therefore, hyperlipidemia is usually also referred to as hyperlipoproteinemia.
2) blood pressure measuring blood pressure inspection diagnosis is adopted; Hypertensive it is characterized by systolic pressure >=140mmHg and (or) diastolic pressure >=90mmHg.
Hypertension is the most common chronic disease, is also the main risk factor of cardiovascular and cerebrovascular disease, and as dead in brain soldier, myocardial infarction, heart failure and chronic kidney disease are all considered as its complication.
This pellet product meets that (" Chinese Pharmacopoeia " version in 2010 annex IA specifies.
Claims (1)
1. a compound antihyperglycemic ball, it is characterised in that: raw material, with the preparation of weight part number, is implemented step by step;
Step 1 feed composition: by Herba Carpesii Cernui 15-25 part, lavandula angustifolia 15-25 part, the real 12-22 part of coriander, Cuscuta 8-15 part, terminalia flesh 25-45 part, the sub-12-25 part of witloof, seed of Herba Apii graveolentis 12-20 part forms; Above-mentioned raw materials being placed in pulverizer pulverize, sieve 80 orders, obtained mixed powder;
Step 2 refines honey: take honey, is placed in furnace pot and is heated to boil, and filters and abandons foam, obtained refining honey;
Step 3 closes medicine: mixed by 1:1 with the medicinal powder of step 1 while hot by the refining of step 2 honey, is placed in stirrer and mixes conjunction evenly, and patent medicine group is for subsequent use;
Step 4 obtains pill: the medicine group of step 3 is placed in the obtained finished product pill of the desk-top pellet processing machine of 0.3g, packs with high-density polyethylene bottle.
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| CN201310263895.3A CN103405498B (en) | 2013-06-27 | 2013-06-27 | A kind of compound antihyperglycemic ball |
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| CN103405498B true CN103405498B (en) | 2016-06-01 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101579027A (en) * | 2008-05-14 | 2009-11-18 | 艾尼·乃木吐力 | Health-care tea for reducing and stabilizing blood pressure |
| CN102973726A (en) * | 2012-12-17 | 2013-03-20 | 艾合买提·艾则孜 | Chinese patent drug for treating hypertension |
| CN103040973A (en) * | 2012-12-31 | 2013-04-17 | 艾合买提·艾则孜 | Compound Chinese patent drug for treatment of hyperlipoidemia |
-
2013
- 2013-06-27 CN CN201310263895.3A patent/CN103405498B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101579027A (en) * | 2008-05-14 | 2009-11-18 | 艾尼·乃木吐力 | Health-care tea for reducing and stabilizing blood pressure |
| CN102973726A (en) * | 2012-12-17 | 2013-03-20 | 艾合买提·艾则孜 | Chinese patent drug for treating hypertension |
| CN103040973A (en) * | 2012-12-31 | 2013-04-17 | 艾合买提·艾则孜 | Compound Chinese patent drug for treatment of hyperlipoidemia |
Non-Patent Citations (3)
| Title |
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| 主治心血管疾病维吾尔药中八种金属元素的测定;王汝静等;《新疆师范大学学报(自然科学版)》;19900402(第1期);第41-44页 * |
| 维药艾菲提蒙汤治疗原发性高血压的临床疗效与安全性评价;阿依努尔•斯马义等;《中药药理与临床》;20120615;第28卷(第3期);第166-168页 * |
| 蒙藏维医药治疗心血管疾病的研究近况;徐永和;《中国民族医药杂志》;20021031;第8卷(第4期);第58-59页 * |
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