CN103405235B - Multi-mode temperature control dynamic test device for blood oxygen differential pressure - Google Patents
Multi-mode temperature control dynamic test device for blood oxygen differential pressure Download PDFInfo
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- CN103405235B CN103405235B CN201310346461.XA CN201310346461A CN103405235B CN 103405235 B CN103405235 B CN 103405235B CN 201310346461 A CN201310346461 A CN 201310346461A CN 103405235 B CN103405235 B CN 103405235B
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- blood oxygen
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Abstract
The open multi-mode temperature control dynamic test device for blood oxygen differential pressure of the present invention, comprise gas cylinder, gas input controller calibration, first Rose Box, second Rose Box, 3rd Rose Box, sample culturing case, blood oxygen dynamic density instrument and blood oxygen analysis instrument, described gas calibration controller connects gas cylinder, described sample culturing case connects blood oxygen dynamic density instrument and blood oxygen analysis instrument, described blood oxygen dynamic density instrument is connected computer controller with blood oxygen analysis instrument, described gas calibration controller connects the first Rose Box successively, second Rose Box, 3rd Rose Box and sample culturing case are assembled into water-bath temperature control module, between described first Rose Box and the second Rose Box, connected by pipeline between second Rose Box and the 3rd Rose Box, described 3rd Rose Box is connected by the valvular pipeline of band with sample culturing case, described sample culturing case connects the first Rose Box and forms residual air blood circulation, described sample culturing case is connected with temperature controller.There is quick heating, the feature that replaces of opening and closing interval.
Description
Technical field
The invention belongs to experimental provision field, be specifically related to a kind of multi-mode temperature control dynamic test device for blood oxygen differential pressure.
Background technology
Body cell, tissue or organ take oxygen and oxygen release dynamic process medium power feature for the various functions of life entity and metabolism most important.Therefore, explore body and take oxygen and oxygen release process medium power basic law, take oxygen and oxygen release function for the generation state of disease under physiology or pathology from cell to Level of organization for furtheing investigate infrastest data are provided.When tradition blood gas analysis only considers resting state, the measurement result of blood sampling point, belongs to the measurement of a single point.Even if the dynamic static alternation two of simulating after improving presses gaseous environment, the dynamic process taken and replace in oxygen and oxygen release process can be investigated to a certain extent, but body body temperature environment or more wide in range variations in temperature can not be simulated completely, just realize the simple opening and closing link controlling gaseous sources.Therefore for thoroughly to realize analog machine internal milieu such as temperature environment, the present invention will make up the deficiency of similar research device in the past, develop there is real-time temperature control, realize sound state dividing potential drop opening and closing interval, alternately and the blood oxygen pressure of the pattern continued detect kinetics charger, with the dynamic blood oxygen pressure kinetic test experiment of the complexity realizing possessing temperature control.
Summary of the invention
The present invention is intended to overcome traditional blood gas analysis can only the deficiency of resting state spot measurement, and one-shot pure simulation sound state binary states air pressure environment and do not consider the defect of body body temperature homeostasis, there is provided a kind of multi-mode temperature control dynamic test device for blood oxygen differential pressure, to realize multifunctional mode and real-time synchronization dynamic to the advantage of data capture.
In order to solve the problems of the technologies described above, the invention provides following technical scheme:
Multi-mode temperature control dynamic test device for blood oxygen differential pressure, comprise gas cylinder, gas input controller calibration, first Rose Box, second Rose Box, 3rd Rose Box, sample culturing case, blood oxygen dynamic density instrument and blood oxygen analysis instrument, described gas calibration controller is connected with three gas cylinders arranged side by side, described sample culturing case is connected with blood oxygen dynamic density instrument and blood oxygen analysis instrument, described blood oxygen dynamic density instrument and blood oxygen analysis instrument are connected to computer controller, described gas calibration controller connects the first Rose Box successively, second Rose Box, 3rd Rose Box and sample culturing case are assembled into water-bath temperature control module, sample culturing case and bag are wrapped in temperature controller, between described first Rose Box and the second Rose Box, connect by installing valvular pipeline between second Rose Box and the 3rd Rose Box, described 3rd Rose Box is connected by the valvular pipeline of band with sample culturing case, described sample culturing case connects the first Rose Box by pipeline and forms residual air blood circulation, the temperature controller that described sample culturing case is bathed by pipeline and circulating distilled water is connected.
Further, described sample culturing case is airtight sample culturing case.
Further, described computer controller and temperature controller are provided with data storage cell.
Further, between the first Rose Box, the second Rose Box, the 3rd Rose Box, connecting pipe is provided with gas pressure sensor control valve.
Further, be provided with horizontal positioned in the first Rose Box, the second Rose Box, the 3rd Rose Box and filter filter paper.
Compared with prior art, the present invention has following beneficial effect:
(1) this sample culturing case utilizes circulating distilled water bath enforcement temperature control simple, and cost is lower, and be easy to dismounting, programming rate is very fast.
(2) 3 step by step Rose Box coordinate detachable 0.22um to filter filter paper, can carry out thoroughly degerming to gas, aseptic to ensure the gas passed in the sample cell of sealing, thus reach take oxygen and oxygen release dynamic process research uninterruptedly or seriality.
(3) the style product that the pump into incubator sealed can realize balanced temperature field, and can realize wide in range temperature gradient field by the temperature controlling water-bath.
The gas pressure sensor control valve of (4) 3 hoses connected between Rose Box step by step can air pressure in management and control sample culturing case, accurately to realize taking sound state dividing potential drop opening and closing interval in oxygen and oxygen release process, alternately and the various pattern continued.
Accompanying drawing explanation
Fig. 1 is the structural representation of multi-mode temperature control dynamic test device for blood oxygen differential pressure of the present invention.
Detailed description of the invention
Below in conjunction with accompanying drawing, the preferred embodiments of the present invention are described, should be appreciated that preferred embodiment described herein is only for instruction and explanation of the present invention, is not intended to limit the present invention.
As shown in Figure 1, multi-mode temperature control dynamic test device for blood oxygen differential pressure, comprise gas cylinder 1, gas input controller calibration 2, first Rose Box 3, second Rose Box 4, the 3rd Rose Box 5, sample culturing case 6, blood oxygen dynamic density instrument 7 and blood oxygen analysis instrument 8, gas calibration controller 2 is connected with three gas cylinders 1 arranged side by side, this gas calibration controller 2 connects the first Rose Box 3, second Rose Box 4, the 3rd Rose Box 5 and sample culturing case 6 successively and is assembled into water-bath temperature control module, and sample culturing case is airtight sample culturing case.Sample culturing case 6 is wrapped in temperature controller 11, between the first Rose Box 1 and the second Rose Box 2, connect by installing valvular pipeline between second Rose Box and the 3rd Rose Box 3, described 3rd Rose Box 5 is connected by the valvular pipeline of band with sample culturing case 6, described sample cell 6 is connected with blood oxygen dynamic density instrument 7 and blood oxygen analysis instrument 8, blood oxygen dynamic density instrument 7 and blood oxygen analysis instrument 8 are connected to computer controller 9, sample cell 6 connects the first Rose Box 3 by pipeline and forms residual air blood circulation, the temperature controller 11 that described sample culturing case 6 is bathed by pipeline and circulating distilled water is connected.Described computer controller 9 and temperature controller 11 are provided with data storage cell, store the data detected in real time.Between first Rose Box, the second Rose Box, the 3rd Rose Box, connecting pipe is provided with gas pressure sensor control valve, be provided with horizontal positioned in first Rose Box, the second Rose Box, the 3rd Rose Box and filter filter paper, filter filter paper and be positioned at Rose Box height 1/2 place.Fixed by 4 corner screws between the upper and lower two parts of Rose Box.
After gas input aligner, after calibration, three kinds of gases are with after certain proportion mixing, be connected into the first Rose Box 3 successively, second Rose Box 4, it is degerming that 3rd Rose Box 5 carries out hybrid filtering, sample cell accepts very even 3 kinds of gases, the described blood oxygen dynamic density instrument that controlled by computer controller and blood oxygen analysis instrument can realize measuring the aerobic of biological sample by Real-Time Monitoring, under the different oxygen proportion by subtraction of anoxia or anaerobism, take the dynamic change of oxygen and oxygen release process, described circulating distilled water bath apparatus 10 carrys out the temperature of accurate Quality control incubator by distillation water-bath circulation, reach temperature control, described residual air cycle cooling plating drum connects output channel by sample culturing case 6 and returns Rose Box 1, carry out gas again to circulate.
The foregoing is only explanation embodiments of the present invention; be not limited to the present invention, for a person skilled in the art, within the spirit and principles in the present invention all; any amendment of doing, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (2)
1. multi-mode temperature control dynamic test device for blood oxygen differential pressure, comprise gas cylinder, gas input controller calibration, first Rose Box, second Rose Box, 3rd Rose Box, sample culturing case, blood oxygen dynamic density instrument and blood oxygen analysis instrument, it is characterized in that, described gas calibration controller is connected with three gas cylinders arranged side by side, described sample culturing case is connected with blood oxygen dynamic density instrument and blood oxygen analysis instrument, described blood oxygen dynamic density instrument and blood oxygen analysis instrument are connected to computer controller, described gas calibration controller connects the first Rose Box successively, second Rose Box, 3rd Rose Box and sample culturing case are assembled into water-bath temperature control module, sample culturing case and bag are wrapped in temperature controller, between described first Rose Box and the second Rose Box, connect by installing valvular pipeline between second Rose Box and the 3rd Rose Box, described 3rd Rose Box is connected by the valvular pipeline of band with sample culturing case, described sample culturing case connects the first Rose Box by pipeline and forms residual air blood circulation, the temperature controller that described sample culturing case is bathed by pipeline and circulating distilled water is connected, first Rose Box, second Rose Box, between 3rd Rose Box, connecting pipe is provided with gas pressure sensor control valve, described sample culturing case is airtight sample culturing case, described computer controller and temperature controller are provided with data storage cell.
2. multi-mode temperature control dynamic test device for blood oxygen differential pressure according to claim 1, its feature is, is provided with horizontal positioned and filters filter paper in the first Rose Box, the second Rose Box, the 3rd Rose Box.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310346461.XA CN103405235B (en) | 2013-08-09 | 2013-08-09 | Multi-mode temperature control dynamic test device for blood oxygen differential pressure |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201310346461.XA CN103405235B (en) | 2013-08-09 | 2013-08-09 | Multi-mode temperature control dynamic test device for blood oxygen differential pressure |
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| Publication Number | Publication Date |
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| CN103405235A CN103405235A (en) | 2013-11-27 |
| CN103405235B true CN103405235B (en) | 2016-03-02 |
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| CN201310346461.XA Expired - Fee Related CN103405235B (en) | 2013-08-09 | 2013-08-09 | Multi-mode temperature control dynamic test device for blood oxygen differential pressure |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104864898B (en) * | 2014-02-20 | 2019-04-23 | 中国科学院广州生物医药与健康研究院 | The critique system and method for measurement value sensor in bio-incubator |
| CN111103158B (en) * | 2019-12-18 | 2021-11-16 | 广电计量检测(深圳)有限公司 | Calibration device and method for percutaneous partial pressure monitor |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1058471A (en) * | 1990-07-26 | 1992-02-05 | 赵伟 | Patient's liquid (gas) liquid (gas)-phase gas monitoring instrument |
| US6390977B1 (en) * | 1995-06-07 | 2002-05-21 | Alliance Pharmaceutical Corp. | System and methods for measuring oxygenation parameters |
| CN2300911Y (en) * | 1997-06-11 | 1998-12-16 | 深圳大学 | Electrolyte analyzer for clinical diagnosis |
| JP4441163B2 (en) * | 2002-09-24 | 2010-03-31 | 株式会社フジキン | Oxygen supply water cooling device, filtration device and water cooling device with filtration function using the same |
| CN2689225Y (en) * | 2004-01-15 | 2005-03-30 | 华中科技大学同济医学院 | Multifunctional tissue and organ perfusing device |
| CN2878398Y (en) * | 2005-11-24 | 2007-03-14 | 上海中医药大学 | Determination device for unorganized tissue function |
| CN101158676B (en) * | 2006-12-31 | 2011-12-14 | 重庆大学 | Analysis method and device for evaluating blood and crucifixes oxygen carrying and oxygen releasing function thereof |
| CN201260941Y (en) * | 2008-09-02 | 2009-06-24 | 深圳市美的连电子科技有限公司 | Gas mixing and proportioning equipment |
| CN101498713B (en) * | 2009-01-16 | 2012-07-18 | 中国医学科学院生物医学工程研究所 | Blood-gas reaction monitoring and control device |
| CN203044041U (en) * | 2013-02-01 | 2013-07-10 | 山东大学 | Constant-temperature water bath experiment device |
| CN203388864U (en) * | 2013-08-09 | 2014-01-15 | 兰州大学 | Multimode temperature control type blood oxygen partial pressure dynamical test device |
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